Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 25 A New Beginijihg |or Human Health * Volume 4 of 4 Conference Chair and Co-Chair Jorge E. Monzon Jose C, Pri 17-21 September 2003 Cancun, Mexico Program Chair and Co-Chair Joaquin Azpiroz Leehan loatrieux UNIVERSlTATSBlBUOTr, > HANNOVER TECHN!SCHE tNFORMATIONSSiBUOTHEKj Publications Chair Ron S. Leder _i _! _| >AV EMB Casa abierta al tiempo —Co- coral
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Volume25 Beginijihg |or Volume UNIVERSlTATSBlBUOTr, …4. Optimizationof PulseSequences for LactateDetection UsingMRSpectroscopy 3079 Rao, H B Wu,R H Xiao, Z W Zheng, WB Liu, G R Kong,
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Proceedings of the 25th
Annual International Conference ofthe IEEE
Engineering in Medicine and Biology Society
Volume 25
A New Beginijihg |or Human Health
* Volume 4 of4
Conference Chair and Co-Chair
Jorge E. Monzon
Jose C, Pri
17-21 September 2003
Cancun, Mexico
Program Chair and Co-Chair
Joaquin Azpiroz Leehan
loatrieux
UNIVERSlTATSBlBUOTr, >
HANNOVER
TECHN!SCHE •
tNFORMATIONSSiBUOTHEKj
Publications Chair
Ron S. Leder
_i _! _| >AV EMBCasa abierta al tiempo —Co-
coral
2. A Bayesian Classifier for Baby's Cry in Pain and Non-Pain Contexts 2944Baeck, Heidi L"
, Souza, Marcio N,hcdera] University of Rio de Janeiro/COPPF
3. Prediction of Epileptic Seizures Using Bispectrum Analysis of Electroencephalograms and Artificial Neural Network ...2947Huang, I lyu, Sun.Qixin, Cheng, Jingzhi, Huang, Yuangui, Xi-an Jiaotong University
4. Analysis and Classification of Respiratory Sounds by Signal Coherence Method 2950Baydar, K Serhat, hrtuzun, Aysin, Kahya, Yascmin P
, Bogazici Universty
5. Evaluation of Cosine Radial Basis Function Neural Networks in Detection of Artifacts in Neonatal EEG 2954Mukherjee, Amit Karayiannis, Nicolaos B
, Glover, John R, Hrachovy, Richard A
, Fiost, Jr, James D, Mizrahi, Eli M
, Universityof Houston
6. Dysphonic Voice Classification Using Wavelet Packet Transform and Artificial Neural Network 2958Scluick Jr, Adalberto, GuimarSes, Leticia V
, Wisbeck, John 0,Universidade Tederal do Rio Grande do Sul
7 A Comparison of String Kernels and Discrete Hidden Markov Models on a Spanish Digit Recognition Task 2962Goddard, John C
, Martinez, Alma, Martinez, Pabiola, Rullner, Hugo L, Universidad Autonoma Metropohtana
Track 7.7: Drug Delivery and Pharmacokinetics
John Li, Rutgers University, Semahat Demir, Univ of Memphis & Umv of Tennessee, Isik Univ, Carmelina Ruggiero, University of Genoa
Session 7.7.1: Drug Delivery and PharmacokineticsSemahat Demir, Univ of Memphis & Univ ofTennessee, Isik Univ
Friday Sep-19-2003, 8:00 -10:00 (Coral Garden I, Slide)
1. Network Thermodynamic Model of Drug Transfer through Skin for Transdermal Drug Delivery in Vitro 2966
Wang, Hong, Bao, Jiali, Ge, Jiguang, Wu, Ping, College ofMedicine, Zhejiang University
2. Multi-Pulse Generator for Electroporation 2970Ping, Wu, Jiah, Bao, Hong, Wang, Huiping, Wang , College ofMedicine, Zhejiang University
3. Phenomenological Analysis of Drug Transport through Stratum Corneum 2974
Bao, Jiali, Wang, Hong, Ge, Jiguang, Wu, Ping, Wang, Huiping, College of Medicine, Zhejiang University
4. Patient Illness Classification Using Time-Frequency Features Derived from the Photoplethysmogram 2978Watson, James N
, Addison, Paul S, Leonard, Paul, Beattie, Thorn F , Napier University
5. Transdermal Drug Delivery: a Comparative Analysis of Skin Impedance Models and Parameters 2982
Coston, Anthony F, Li, John K. J
,Ethicon Inc
Theme 8. Instrumentation, Sensors, and Measurements
Toshiyo Tamura, Nils, Yuan-Ting Zhang, The Chinese University of Hong Kong
Track 8.1: Sensors
Toshiyo Tamura, Nils
Session 8.1.1: Biosensors
Masakt Yamaguchi, Toyama University
Thursday Sep-18-2003, 10:30 - 12:30 (Coral Sea II, Slide)
1. Fiber Optic Biosensors Comprising Nanocomposite Multilayercd Polymer and Nanoparticle Ultrathin Films 2987Grant, Patrick S , Kaul, Swati, Chinnayelka, Swetha, McShane, Michael J, I ouisiana Tech University
2. A Microfluidic Bioreporter System for Space Flight Monitoring 2991
Towc, Bruce C, Martineau, Rhett L
, Cooncy, Christopher G , Pictini, Matthew E, Daydif, Patrick, Stout, Valerie, Arizona State
University
3. Survival-Time Analysis of the Postpartum Anovulatory Interval as Measured by Rise in Urinary Pregnanediol-3-Glucuronidc in Lactating Women 2995
Taylor, llany W ,West Virginia University Institute of Technology
4. Acoustic Immunosensor for Real-time Sensing of Neuiotransmittcr GABA 2998
Wang, Imgling, Mulluiswamy, lit, Arizona State Unvicrsity
6. Comparison of Conformal and Nonconformal Meshes in the Electromagnetic Simulation of Atherosclerotic Lesions 3O05
Stiles, David K, Oakley, Barbara A
,Oakland University
7. A No\cl Biosensor for On-line Dialysis Monitoring 3O09
Staneoki Catheime f, McShane. Michael J
, Hannibal, Anna M , Dnggcrs, Keun II, Watts, Alan
,Louisiana lech University
Contents - 43
Session 8.1.2: Wearable Sensors and ComputersRamon Pallas-Areny, Technical University Catalonia (upc)
Thursday Sep-18-2003, 16:00 -18:00 (Coral Sea II, Slide)
1. Wearable Sensor System for Wireless State-of-Hcalth Determination in Cattle 3012
NagI, Luke J, Schmitz, Ryan, Warren, Steve, Hildrelh, Tammi S
, Enckson, Howard, Andrcsen, Daniel, Kansas State Univeisity
2. Measurement Site and Photodctector Size Considerations in Optimizing Power Consumption of a Wearable
Reflectance Pulse Oximeter 3016
Mendelson, Yitzhak, Pujary, Chirag, Worcester Polytechnic Institute
4. A Ring-Shaped EMG Measurement System for Applying to User Interface 3020
1. Pyroelectric Properties of Pb0.88(ln)0.08ti0.98mn0.02o3 (In = La, Sm, Eu) Piezoceramics for Biomedical Use 3032Gonzalez, Ruben, Castillo, Victor, Suaste, Ernesto
,CINVESTAV-IPN
2. Thermal and Electrical Characterization ofthe Intervertebral Disc 3035Sierra, Gilberto, Leung, Mark, Le Guyader, Pierre, Savard, Pierre, Ecole Polytechnique
3. Tunnel Diode Oscillator Applied as Sensor-Modulator for Telemetry of Temperature in Human Beings and Animals ...3037Villamar, Luis A
, Suaste, Ernesto,CINVESTAV-IPN
4. Inductively Powered Implantable Microcoil Temperature Measurements: Safety Implications and OperationalGuidelines 3041Choi, Woohyek, Ziaie, Babak, University ofMinnesota
1. Solenoidal and Planar Microcoils for Nmr Spectroscopy 3045Armenean, Mircea, Beuf, Olivier, Renaud, Louis, Saint-Jalmes, Herve, Laboratoire de RMN, Univ Claude Bernard LYON 1
2. The Use of Surface Enhanced Raman Spectroscopy (sers) in a ComPETltive Affinity Binding Assay for the Detectionof Prions 3049Chowdhury, Mustafa, Anand, Ashish; Henry, James, Moreira, Rosana, Good, Theresa, Cot6, Gerard, University of Maryland Baltimore
County
4. On the Design of a Swept Field Aspiration Condenser Measurement Cell 3052Solis, Andro A , Sacristan, Emilio, UAM-Iztapalapa
5. Practical Method for Photon Fluency Evaluation of Digital X-Ray Image System 3056Albuquerque, Jorge A G, Costa, Eduardo T
, Boscolo, Frab N, Unicamp
6. Towards Fluorescence Anisotropy Detection for Real-Time PCR Assays 3060Crane, B
, Sudo, H , Thilly, W G, Hunter, I W
,MIT
7. In-Vitro and In-Vivo Measurement of Iron Concentration In Human Hepatic Tissue by Magnetic Induction Methods
3064Casaftas, Roberto, Scharfetter, Hermann, Altes, Albert, Rctnacha, Angel, Sarda, P
, Sierra, J, Merwa, Robert, 1 lollaus, Karl, Rosell,Javier, Universitat Politecnica de Catalunya
1. Calibration and Testing in Voltammetric and Amperomctric Sensor Measurements 3068Vrba, Radimir, Pavel, Steffan, Martin, Adamek, Krejci, Jan, Prasek, Jan
,Brno University of technology
2. Simple Characterization of Acetylcholinesterase by Electrochemical Sensor 3071Ondruch, Vit, Krejci, Jan, Krejcova, Dagmar, Vrba, Radimir, Brno University of Technology
3. Salivary Amylase Activity Monitor Used for Stress Evaluation 3075Yamaguchi, Masuki, Kanemaru, Masashi, Kanemon, Takahiro, Mizuno, Yasufumi, Yosluda, lliroshi, loyama University
Contents - 44
4. Optimization of Pulse Sequences for Lactate Detection Using MR Spectroscopy 3079
Rao, H B, Wu, R H
, Xiao, Z W, Zheng, W B
, Liu, G R, Kong, K M
, Lang, Z J, Second hospital of Shantou Univ Medical
1. Application of the Reciprocity Theorem to Volume Conduction Based Data Communication Systems BetweenImplantable Devices and Computers 3352Sun, Mmgui, Liu, Qiang, Liang Wei, Wessel, Bnan L
, Roche, Paul A, Mickle, Marhn, Sclabassi, Robert J
, University of Pittsburgh
2. A Volume Conduction Antenna for Implantable Devices 3356Sun, Mingui, Wessel, Brian L, Liang, Wei, Roche, Paul A
,1 iu, Qiang, Mickle Marhn, Sclabassi, Robert J, University of Pittsburgh
3. Stentenna: A Micromachined Antenna Stent for Wireless Monitoring of Implantable Microsensors 3360Takahata, Kcnicln, DcIIennis, Andrew, Wise, Kensall D
, Gianchandam, Yogcsh B, University of Michigan
4. Benzocyclobutene (BCB) Based Intracortical Neural Implant 3364Singh, Amarjit, Lee, Kee-Keun, He, Jiping, Ehteshann, Gholam, Massia, Stephen, Raupp, Gregory, Arizona State University
5. Inductive Link Modeling and Design Guidelines for Optimum Power Transfer in Implantable WirelessMicrosystems 3368Salim, Amani, Choi, Woohyek, Baldi, Antonio, Ziaie, Babak, University of Minnesota
6. Integrated Multi-Channel Wireless Biotelemetry System 3372DeMichele, Glenn A
, Troyk, Philip R, Sigenics Inc
7. Inductively-Coupled Power and Data Link for Neural Prostheses using a Class-E Oscillator and FSK Modulation 3376Troyk, Philip R , DeMichele, G A
1. A Micro-Fluidic Ultra-Violet Emission Source For Direct Fluorescence of Tryptophan '. 3380Mitra, Bhaskar, Wilson, Chester, Que, Long, Gianchandam, Yogesh, University of Michigan
2. Fabrication and Deployment of Nanoscale Fluorescent Intracellular Probes, 3384
Brown, J. Quincy, Guice, Kyle B., Caldorera, Mary E , McShane, Michael J., Louisiana Tech University
3. Separation of Blood in MicroChannel Bends 3388Blattcrt, Chnstoph, Junschka, Reinhold, Schoth, Andreas, Kerth, Paul, Menz, Wolfgang, University of Freiburg
4. Integrated Ce Chip - Concentration and High-Resolution Cyclic Ce Technology 3392Jeong, Yongwon ,
Seoul National university
5. A Custom Multielectrode Array with Integrated Low-Noise Preamplifiers 3396Blum, Richard A
, Ross, James D, Simon, Crystal M , Brown, Edgar A
, Harrison, Reid R ; DeWeerth, Stephen P , Georgia Institute of
Technology
6. Design and Implementation Considerations for an Advanced Wireless Interface in Miniaturized Integrated Sensor
Microsystems 3400
Aydin, Nizamettin, Astaras, Alexandros, Wang, Lei; Arslan, Tughrul, Murray, Alan F, Cumming, David R S,The University of
Edinburgh
7. A Microfluidic Channel for Cell Separation 3403Li, Youlan, Kaler, Karan VIS, University of Calgary
8. Computer Simulation of Stress Analysis in Benzocyclobutene (BCB) Based Neural Interface 3407Yun, Wenjun, Singh, Amarjit, He, Jiping, Lee, Kce-Keun, Kim, Bruce, Arizona State University
3. Skin Misture Measurements Based on Near-Infrared Spectroscopy and Regression Analysis 3438
Anmoto, Hidenobu,AIST
4. A Rapid, Whole Blood Immunoassay using Metal Nanoshells 3442
Hirsch, Leon R ; West, Jennifer L; Jackson, Joseph B.; Lee, Allen; Halas, Naomi J., Rice University
5. Temperature Sensor for Medical Applications Based on Erbium Doped Optical Fiber 3444
Escudcro-Unbe, Apolo Z., Instituto Nacional de Astrofisica 6ptica y Electr6
6. Analysis of Longer Wavelength Alexafluor Dyes for Use in a Minimally Invasive Glucose Sensor 3446
Ibey, Bennett L, Cote, Gerard L, Yadavalli, Vamsi; Gant V. Alexander; Newmyer, Keith; Pishko, Michael V., Texas A&M University
Theme 9. Professional Activities and Education
Robert Munzner, www.doctordevice.com, Grace Bartoo, Instruments for Science & Medicine, Inc.
Track 9.1: History of Biomedical EngineeringRon Leder, UAM
Session 9.1.1: BME in Latin America and the World
Ron Leder, UAM; Joaquin Azpiroz-Leehan, Universidad Autonoma Metropolitana-Iztapalapa
Saturday Sep-20-2003, 8:00 -10:00 (Coral Island II, Slide)
1. Overview of the Biomedical Engineering History in Mexico 3450Cadena Mindez, Miguel; Azpiroz-Leehan, Joaquin , Universidad Autonoma Metropolitana-Iztapalapa
2. CORAL and Its Role in Latin America Over the Last Decade 3454Monzon, Jorge E., Universidad Nacional del Nordeste
Session 9.1.2: Great Contributors to BME Featuring Otto Schmidt
Robert Patterson, University of Minnesota
Saturday Sep-20-2003, 8:00 -10:00 (Coral Island II, Slide)
1. Otto Herbert Arnold Schmitt (1913-1998): Overview of His Scientific Production 3457Valentinuzzi, Max E., Universidad Nacional de Tucuman
2. Otto Schmitt: a Father of Biomedical Engineering and Master Gadgeteer 3461Patterson, Robert P., University of Minnesota
Track 9.2: Ethics in Biomedicine'
jbrata Saha, Alfred University
Session 9.2.1: Ethical Dilemmas in BME
Subrata Saha, Alfred University
Friday Sep-19-2003, 13:30 - 15:30 (Coral Island II, Slide)
1. University-Industry Relationships: Ethical Challenges 3464Saha, Subrata, Saha, Pamela, Alfred University
2. Teaching Ethics for Biocngineers in the 21st Century 3466Fri/.c, Monique , Carlclon University
3. Service Learning Experience: Design of Devices to Aid Children with Disabilities 3469Saha, Subrata, Alfred University
Contents - 50
4. A Secure Database for Human Specimen Repositories 3471A/evedo, Dano G
, Souza, Antonio C , Glock, Flavio S, Russomano, Thais, Glock, Silvio S
,Pontificia Universidade Catolica do RGS
Track 9.3: BME EducationBarbara Oakley, Oakland Univeisity, Semahat Demir, Univ of Memphis & Univ ofTennessee, Isik Univ
Session 9.3.1: Best Practices in Promoting the BME Profession
Barbara Oakley, Oakland University
Thursday Sep-18-2003, 10:30 -12:30 (Coral Sea I, Slide)
1. A Possible EMB Award Recognizing Excellent Research by Graduate Students 3474Barr, Roger C , Johnson, Chad R
,Duke University
2. Promoting Biomedical Engineering through Recruitment 3475Chan, Adrian D C , Carleton University
3. BME Education Program at the EMBS Student Club of Beijing University of Posts and Telecommunications 3479Wu, Yunfeng, Mitsui, Mic, Beijing University ofPosts and Telecommunications
4. Biomedical Engineering Minor: an Option for EE Students in Argentina 3483Monzon, Jorge E
,del Valle, Eduardo E
, Valdez, Alberto D, Alvarez, Carlos, Universidad Nacional del Nordeste
5. Rethinking the Undergraduate Biomedical Engineering Curriculum After an Analysis of the 20 Previous Years 3486Medal, E G Urbina, Azpiroz-Leehan, Joaquin, Umversidad Autonoma Metropolitana-Iztapalapa
6. Student Leadership: Biomedical Engineering Initiatives at Carleton University 3490
Herry, Chnstophc L, Catley, Chnstina, Ennett, Colleen M,Carleton University
7. A Mentoring Program for Women in the Joint Graduate Biomedical Engineering Program of University of Memphisand University ofTennessee 3494Demir, Semahat S
,Univ ofMemphis & Univ ofTennessee, Isik Univ
Session 9.3.2: Computational and Simulation Resources in BME EducationSemahat Demir, Univ of Memphis & Univ of Tennessee; Isik Univ
Friday Sep-19-2003, 8:00 -10:00 (Coral Island II, Slide)
1. Applications of Computational Models in Education 3497
Stevens, Carey, Diebel, Carol, E, Malpas, Simon C , Hunter, Peter J, University ofAuckland
2. Peer-Reviewed Literature - A Resource for Teaching Mathematical Modeling to Undergraduates in Biomedical
Engineering 3499Blanchard, Susan M , Martin, Penney J
,North Carolina State University
3. ICELL: an Interactive Web Resource for Simulation-Based Teaching and Learning in Electrophysiology Training 3501
Demir, Semahat S,Univ of Memphis & Univ ofTennessee, Isik Univ
4. NLX: Building Web Pages With Interactive Calculations in Minutes 3505
Kootsey, J Mailcn, McAulcy, Grant, Loma Linda University
5. Electrical Interactions Between Cardiac Cells: What Can We Learn from Two-Cell Systems? 3509
Wilders, Ronald, Vcrkcrk, Anc O, Verheijck, E Eticnne, Kumar, Rajiv; Wagner, Mary B , Wang, Yanggan, Joyner, Ronald
W,Academic Medical Center, University of Amsterdam
6. Inquiry-Based Biomedical Signal Processing Laboratory: from Practice to Simulation 3513
Macy, Alan J,BIOPAC Systems, Inc
7. The Implementation of an EMG Controlled Robotic Arm to Motivate Pre-College Students to Pursue Biomedical
Engineering Careers 3517
Mooic, Eugene J,Dc Marco, Robert M
, Foulds, Richard A, Alvaiez, Tara L
,New Jersey Institute of Technology
Session 9.3.3: Education: Best Practices in Promoting the BME Profession 2
Semahat Demir, Univ of Memphis & Univ of Tennessee, Isik Univ; Barbara Oakley, Oakland University
1. A Coding Algorithm for SMS Data Transmission in Tele-Home Care System 3672
Xu, Xiaomin, Liu, Ymg, University ofPortsmouth
2. Safe Control of Ultrasound Probe on Abdomen by Pulling Cables for Robotic Tele-Echography System 3676
Masuda, Kohji, Vilchis, Adriana, Troccaz, Jocelyne, Cinquin, Philippe, Tokyo University A&T
3. Possibilities to Use the Practice of Telemedicine in Actual Technological Conditions to Remote Areas 3680Kmeteuk, Osmir F , Amonm, Mardson F
,PUCPR
Track 11.4: Shared Clinical Engineering Issues in Latin and North America
Session 11.4.1: Shared Clinical Engineering Issues in Latin and North America
Yadin David, Texas Childrens Hospital
Saturday Sep-20-2003, 10:30 - 12:30 (Coral Island I, Slide)
1. Evaluation and Selection of General Purpose Infusion Pumps 3683Tox, Torrest, The Methodist Hospital
2. The Development of Clinical Engineering in Latin America and the Caribbean 3684Hernandez, Antonio
,Pan American Health Organization / World Health Or
3. Biomedical Engineering Equipment Management System (BEEMS) 3685Molina, Claudia P
, David, Yadin, Texas Children's Hospital
Contents - 54
Theme 12. Mini-SymposiaMetin Akay, 8000 Cummings Hall, Frank Eisenhaber, Imp, David Fenstermacher, University ofNorth
Track 12.1: Novel Technologies: Genomics and Neuroengineering
Session 12.1.1: Mini-symposium: Interfacing In-Vitro Neural Networks to ComputersThomas Coates, Jr, University of Kentucky, Greg Gcrhardt, University of Kentucky
Friday Sep-19-2003, 8:00 -10:00 (Coral Sea I, Slide)
1. Studying Mammalian Neurons in Vitro with Multielcctrode Arrays 3686Pine, Jerome
,Caltech
2. Long-Term Bidirectional Neuron Interfaces for Robotic Control, and in Vitro Learning Studies 3690
Potter, Steve M, Georgia Tech
Session 12.1.2: Mini-symposium: Novel Technologies for Brain-Machine InterfacingGreg Gcrhardt, University ofKentucky, Thomas Coates, Jr., University of Kentucky
Friday Sep-19-2003, 13:30 -15:30 (Coral Sea I, Slide)
1. Microfabricated Ceramic Sensor Arrays for Direct Interfacing to Deep Brain Structures in Primates 3694
Coates, Jr, Thomas D, Hampson, Robert, Deadwyler, Sam, Gerhardt, Greg A , University of Kentucky
2. Nanostructured Porous Silicon Scaffolds for Improved Biocompatibility of Thin Film Microelectrodes 3698
Moxon, Karen A,Drexcl University
3. Ceramic-Based Microelectrode Neuronal Recordings in the Rat and Monkey 3700
Hampson, Robert E, Coates, Jr, Thomas D ; Gerhardt, Greg A , Deadwyler, Sam A., Wake Forest University School of Medicine
4. Clinical Considerations for the Rapid Electrochemical Detection of Glutamate in the Intra-operative and Long-termMonitoring 3704van Home, Craig G , Brigham and Women's Hospital - Harvard Med Sen