Viruses I. What are they (and what aren’t I. What are they (and what aren’t they)? they)? II. Virus structure and II. Virus structure and classification classification III. Viral infection III. Viral infection Herpesvirus Herpesvirus Foot and Mouth Disease virus Foot and Mouth Disease virus Ebola virus Ebola virus
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Viruses I. What are they (and what aren’t they)? II. Virus structure and classification III. Viral infection Herpesvirus Foot and Mouth Disease virus Ebola.
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VirusesViruses
I. What are they (and what aren’t they)?I. What are they (and what aren’t they)?
II. Virus structure and classificationII. Virus structure and classification
III. Viral infectionIII. Viral infection
HerpesvirusHerpesvirus
Foot and Mouth Disease virusFoot and Mouth Disease virus
Ebola virusEbola virus
Characteristics of VirusesCharacteristics of Viruses
Somewhere between life and non-lifeSomewhere between life and non-life
Can’t reproduce or __________________ independentlyCan’t reproduce or __________________ independently
But But cancan direct living cells to do so for them direct living cells to do so for them
Composed of Composed of only one or two only one or two different proteins different proteins + nucleic acid+ nucleic acid
AdenovirusesAdenoviruses -- non-enveloped icosahedral viruses which are generally -- non-enveloped icosahedral viruses which are generally
mild pathogens in humans, birds, etc. causing ___________________ mild pathogens in humans, birds, etc. causing ___________________
(‘pink eye’) and _________________ illnesses.(‘pink eye’) and _________________ illnesses.
Complex virusesComplex viruses
A number of types with somewhat more ___________ A number of types with somewhat more ___________ structuresstructures
One is typical bacteriophage, with icosahedral head, helical One is typical bacteriophage, with icosahedral head, helical tail, fibers for attachmenttail, fibers for attachment
Bacteriophage Bacteriophage
lambdalambda
Nucleic acid contentNucleic acid content
Viral genomes are very smallViral genomes are very small ___________ base pairs (enough to encode 3 or ___________ base pairs (enough to encode 3 or
4 proteins) to 200,000 bp4 proteins) to 200,000 bp
Small compared to bacteria (~10Small compared to bacteria (~1066 bp) and bp) and
human (~2 X 10human (~2 X 1099 bp). bp).
Characterized by __________________ genesCharacterized by __________________ genes