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UTI DURING PREGNANCY_PRESENTED AT HMAI 2010

Apr 09, 2018

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Saurav Arora
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    -DR ARCHANA NARANG, MEDICAL OFFICER (T), MD, ISM & H,

    -DR SAURAV ARORA, SENIOR RESEARCH FELLOW, SHMC & H

    [email protected]

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    UTI:-

    Common afliction to seek medicalattention

    Infancy to old age

    The most common infections during

    pregnancy In pregnancy, the rate of progression of

    lower UTI to pyleonephritis is reported tobe as high as 40 %

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    UTI is defined as the presence of at least100,000 organisms per milliliter of urine

    in an asymptomatic patient or as morethan 100 organisms per milliliter of urine

    with accompanying pyuria (>7 WBCs/ml)in a symptomatic patient

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    Usually Acute

    Majority due to a single pathogen

    Usually an Enterobacteriaceae 90% of all UTI

    Gram negative bacilli

    Common intestinal flora

    Escherichia coli most commonly isolatedpathogen ~80% of all UTI

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    Increased frequency and urgency of urination

    Dysuria

    Retropubic/suprapubic/renal area pain duringor after urination

    Sudden onset of pain in one or both of the loinsradiating to iliac fossae and suprapubic area

    Cloudy urine with unpleasant odor

    Hematuria

    Fever with rigors and vomiting

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    Asymptomatic bacteriuria (ASB) More than 100,000 organisms/ml in 2 consecutive urine

    samples in the absence of symptoms (found in 2-10% ofcases)

    Most common pathogen-E coli. (Isolated in 80-85% ofcultures). Others are: Klebsiella pneumoniae (5%),Enterobacter species (3%), Group B beta-hemolytic

    streptococcus (1%) Upper urinary tract infection (Cystitis)

    Lower urinary tract infection (Acutepyelonephritis)

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    Physiological changes during pregnancy

    Hormonal and mechanical changesincrease the risk of urinary stasis inpregnancy resulting in urinanry tractinfections(UTI)

    Difficulty in maintaining hygiene may alsolead to increase in frequency of urinarytract infections (UTI) in pregnant women

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    Virulence Host factors

    Infection No infection

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    Fetal complications

    Preterm labor, prematurity, low birthweight

    Intrauterine growth retardation,neonatal death

    Maternal complications

    Anemia, hypertension, transient renalfailure

    Acute respiratory distress syndrome,sepsis

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    Untreated upper UTIs have been associatedwith a low birth weight, prematurity,premature labor, hypertension and/orpreeclampsia, anemia

    There is increased tendency in progressionof lower UTIs (cystitis) to pyelonephritis inpregnant patients (40%of cases)

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    A 27 year old pregnant female, dentist byprofession, in 30thweeks of gestation

    presented with following symptoms: Pain in pubic region after urination

    Increased frequency of urination

    Increased urgency of urination

    Cloudy urine with unpleasent smell

    Her routine lab investigations done 15 days back were normal

    On the basis of above symptoms Urinary Tract Infection was

    suspected

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    Urine: routine/microscopic

    Dipstick to detect white blood cells

    Reports revealed:

    Turbid urine with traces of albumin

    Pus cells 35-40/hpf

    Epithelial cells many/hpf

    Bacetria 1+/HPF

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    URINARY TRACT INFECTION

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    Homoeopathic treatment: Patient was puton Equisetum 30 on the basis of symptomsimilarity

    Following symptoms were taken into

    consideration:

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    Severe dull pain in the bladder region as from distension,not better after urinating.

    Frequent and intolerable urging to urinate, with severe pain

    at close of urination; urine flows only drop by drop. Passes large quantity of clear, watery urine, without relief.

    Sharp, burning, cutting pain in urethra while urinating.

    Retention and dysuria during pregnancy and after delivery.

    Albuminuria and involuntary urination.

    Pain deep in region of right kidney, extending to lowerabdomen, with urgent desire to micturate; right lumbarregion painful.

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    Auxillary methods adopted

    Advise to increase fluid intake

    Advise to empty bladder as soon as thereis urge to urinate

    Review after 7 days with urine test -routine and microscopic

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    Therapeutic, preventive and auxillarymeasures are to be continued

    Follow up every week with urine routineinvestigation

    Advise to report immediately if symptoms

    worsen or she develops fever with rigors& vomiting, sudden severe pain in loins orrenal region

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    Improvement in symptoms of dysuria

    No Pain in pubic region

    Urine examination after 2wks:

    Albumin - Absent

    Pus cells Ocassional

    RBCs Absent

    Bacteria - Absent

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    UTIs are common complications ofpregnancy and may lead to significantmorbidity for both mother and fetus

    All pregnant women should be screened forbacteriuria in the first trimester

    Women with a history of recurrent UTI orurinary tract anomalies should have repeat

    bacteriuria screening throughout pregnancy

    All bacteriuria should be treated duringpregnancy

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    Homoeopathic treatment of pregnant women forASB may prevent morbidity associated withsymptomatic UTIs

    Treatment with Homoeopathic medicines is costeffective, safe and nontoxic to the fetus

    If symptoms worsens or there is no improvementin lab parameters even after 10-15days of

    treatment, patient should be referredWomen should be followed closely after

    treatment of bacteriuria because recurrence mayoccur in up to one third of patients

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