University: Alexandria Faculty: Medicine Program Specifications (Academic year: 2015/2016) A. Basic Information: 1. Program title: Doctor degree of Medical Parasitology 2. Type of program: single 3. Department(s) offering the program: Department of Medical Parasitology 4. Program Coordinator: Prof. Dr. Mona El-Temsahy - Prof. Dr. Lobna El Zawawy 5. External Evaluator(s): Prof. Dr. Stéfane Picot; Prof. of Parasitology and Tropical Medicine, Malaria Research Unit, University Lyon 1, France. 6. Date of program specifications approval: 29/3/2016 B. Professional Information 1- Program Aims are to 1.1 Recognize recent advances in the field of Medical Parasitology. 1.2 Provide professionals with a broad training to be able to examine and diagnose parasitological specimens. 1.3 Prepare the candidate to participate in senior management teams that develop, implement, monitor, evaluate and redevelop polices and strategies to improve diagnosis of parasitic diseases. 1.4 Develop research skills applicable to a wide range of problems in parasitic diseases. 1.5 Prepare the candidate to be an efficient staff member to perform teaching tasks, plan and modify curricula, assess and appraise junior staff. 2. Academic Standards: Academic reference standards of Doctor Degree in Medical Parasitology designed and approved by the Medical Parasitology Department, Faculty of Medicine, Alexandria University. Based on: Generic Academic Reference Standards (ARS): Postgraduate Medical Education, Egypt (2009). Published by National
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University: Alexandria
Faculty: Medicine
Program Specifications
(Academic year: 2015/2016)
A. Basic Information:
1. Program title: Doctor degree of Medical Parasitology
2. Type of program: single
3. Department(s) offering the program: Department of Medical
Parasitology
4. Program Coordinator: Prof. Dr. Mona El-Temsahy - Prof. Dr.
Lobna El Zawawy
5. External Evaluator(s): Prof. Dr. Stéfane Picot; Prof. of
Parasitology and Tropical Medicine, Malaria Research Unit,
University Lyon 1, France.
6. Date of program specifications approval: 29/3/2016
B. Professional Information
1- Program Aims are to
1.1 Recognize recent advances in the field of Medical Parasitology.
1.2 Provide professionals with a broad training to be able to
examine and diagnose parasitological specimens.
1.3 Prepare the candidate to participate in senior
management teams that develop, implement, monitor,
evaluate and redevelop polices and strategies to improve
diagnosis of parasitic diseases.
1.4 Develop research skills applicable to a wide range of
problems in parasitic diseases.
1.5 Prepare the candidate to be an efficient staff member to
perform teaching tasks, plan and modify curricula, assess and
appraise junior staff.
2. Academic Standards: Academic reference standards of Doctor Degree in Medical
Parasitology designed and approved by the Medical
Parasitology Department, Faculty of Medicine, Alexandria
Program in which the Course is Given: Doctor of Medical parasitology
Number of Credit Hours: 2 Theoretical Clinical/Practical
Course aims: Integrated parasitology course focusing on how to develop clinical case study, the
clinical presentations of case, writing the objectives, analyzing data, differential parasitic diagnosis,
the most possible parasitic cause and the treatment of case.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
By the end of the course
graduate must :
a1- Revise the diagnostic
morphology, life cycles, clinical
manifestations, diagnosis and
treatment of the studied parasites.
By the end of integrated parasitology
course the student will be able to:
A1- Define the parasitological causes of
different health issues as fever, diarrheas,
pain, neurological symptoms, skin and
subcutaneous tissue manifestations, and
lymphadenopathy.
A2- Describe the different clinical
manifestations of each case.
A3- Define the newly emerging parasites as
causative agents for the different health
issues related to parasitic diseases.
A4- Describe the different clinical picture
for each newly emerging parasite.
A5-Identify the differential diagnosis of
2
a8- Explain the basis for
therapeutic effects of antiparasitic
drugs and their mode of action.
a10- Identify recent methods for
laboratory diagnosis of parasitic
infections with special emphasis
on molecular techniques.
a13- Trace recent advances in the
field of medical Parasitology and
apply this knowledge in the
diagnosis of parasitic infections.
each case.
A6- Determine the most reliable diagnosis
to each studied case.
A7- Select the recent and the drug of
choice used to treat each case.
A8- Recognize the adverse effects and
mechanisms of resistance to drugs used in
treatment.
A9-Recognize the different recent
diagnostic techniques whether direct or
indirect for each case studied.
A10- Recognize what is new in medical
parasitology especially re- emerging
parasites and imported ones.
A11- Know the recent convenient
techniques which can be used in diagnosis
of related parasitic diseases.
A12- Recognize the recent methods in
diagnosis of related parasitic infections.
B. Intellectual
skills
b1- Interpret the results of direct
parasitological techniques.
b2- Interpret the results of
serologic techniques.
b3- Employ personnel
management principles and apply
workload assessment.
B1- Determine the most diagnostic direct
test suitable for each studied case.
B2- Interpret the results of the direct test
chosen in relation to each case.
B3- Select the most diagnostic serological
test suitable for each studied case.
B4- Interpret the results of the serological
test chosen in relation to each case.
B5- Estimate the level of basic knowledge
that helps in solving common
parasitological problems.
B6- Evaluate skills in solving cases of
endemic nature.
B7- Realize the public health implications
of each case, and means for control for each
parasitic cause.
C.Professional
and Practical
Skills
c5-Evaluate and improve methods
and tools used in specialty.
C1-Use parasitological evidence to solve
each case problem.
C2- Manage case problem in an integrated
manner.
C3- Solve cases which have implication to
c7- Develop new skills or
procedures for new situations such
as emerging and re-emerging
parasitic diseases.
c9- Apply computerized
information systems for recording,
analyzing, and reporting data.
the community.
C4- Prepare data show preparation for each
studied case.
C5- Interpret commonly used
immunological techniques such as ELISA
and immunodiffusion.
C6- Interpret some advanced molecular
methods such as nucleic acid extraction,
PCR amplification and transformation.
C7- Use information technologies to access,
analyze record and report data.
C8- Retrieve information from various
available sources, appraise and systematize
this knowledge.
C9- Conduct skills in specialized diagnostic
tests, including culture techniques and
antigen/antibody detection tests related to
each studied case.
D. General
Skills
d1- Conduct individual
presentations at scientific
conferences that are focused, clear,
and concise and appropriately
utilize time.
d8- Communicate information
clearly both in written and oral
D1- Communicate effectively using written
and oral format to show the results of
investigations related to each case studied.
D2- Use appropriate media for their
presentation.
D3- Co-operate in discussion groups to
solve scientific problems.
D4- Communicate effectively as a director
format.
d10- Retrieve information from all
sources (printed, electronic,
communications etc…).
d13- Demonstrate an ability to use
methods of inquiry to collect and
interpret data in order to provide
information that would reform or
benefit practice.
to show the results of investigations related
to each case studied.
D5- Explain parasitological point of view
in certain studied cases.
D6- Able to represent an evidence-based
presentation about the studied case.
D7- Use different sources of knowledge to
solve the case problem.
D8-Use information technology to solve
the case problem.
D9- Demonstrate decision making skills in
solving endemic parasitic case problems.
D10- Demonstrate skills in collecting data
that help in solving problem.
D11- Demonstrate decision making skills in
unpredictable situations.
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures self-
learning
Practical
/
Clinical
Small
group
discussion
Others
1- Fever in parasitic diseases
2- Diarrhea/ dysentry in parasitic
diseases
3- Nervous system affection in
parasitic diseases
4- Skin and subcutaneous tissue
lesions in parasitic diseases
5- Lymphadenopathy in parasitic
diseases
6- Hepatosplenomegaly in parasitic
diseases
7- Occular lesions in parasitic diseases
8- Anaemia in parasitic diseases
9- Eosinophilia in parasitic diseases
10- Parasitic diseases in children
11- Parasitic diseases in immuno-
compromised patients
12- Nosocomial and laboratory
acquired parasitic infections.
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Discussion
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Discussion
Discussion
Presentation
Presentation
Presentation
Presentation
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Presentation
Presentation
Presentation
Presentation
Presentation
Presentation
Presentation
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment
Mid-term %
End of term 100 %
Distribution of Marks
Group discussion 20 %
Steps for creating the case 30 %
Analysis of data 30 %
Data show presentation 20 %
List of Textbooks and References
Lecture Notes
Parasitology notes
Coulored Atlas of Parasitology
Course Text Books
-Beaver & Jung, Clinical Parasitology,
- Garcia, Diagnostic Medical Parasitology
Suggested Extra Reading
Links of Parasitology from the net
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
- American Journal of parasitology
- Lancet
- Parasitology today
- International journal for parasitology
- Experimental parasitology
- PLOS neglected tropical diseases
Course Instructor:
Ass. Prof. Dr. Maha Reda Gaafar Signature
Program Coordinator
Prof. Dr. Mona El-Temsahy Signature
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Name: Prof. Dr. Lobna El Zawawy Signature
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga Signature
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical Parasitology
Course Information
Course Code: 05190911
Course Name: Seminar II(special topics)
Program in which the Course is Given: Doctor degree of Medical Parasitology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aims: The course of Seminar II: Parasite genomes and proteomes aim at understanding the
scientific means of genomes and proteomes. The course also aims at understanding how
proteomics, the large-scale analysis of proteins, will contribute greatly to understand of gene
function in the post-genomic era. The student will understand how this aspect of proteomic studies
of different parasites is perhaps the area of greatest promise. The aim of the course is also to show
how the integration of the genomic, transcriptomic, and proteomic information, together with
genetic manipulation on individual genes, will provide a global insight into the molecular
architecture of the biology, pathogenesis, and host-parasite interactions of the human and different
parasites. Another aim is to explain how these functional genomics analysis laid a foundation on
which new vaccines develop as well as drug targets and diagnostic markers for treatment and
control of different parasites.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
By the end of the program the
PG students will be able to:
a7- Explain at the cellular and
molecular levels the concept of
pathogenesis and the host-parasite
interactions.
a9- Identify pitfalls and resistance
of current therapy regimens and
the role of recently discovered
antiparasitic drugs.
By the end of the Seminar I the student will
be able to:
A1. Recognize how the host can interact
with the parasite.
A2. Determine the proteins generated from
this reaction and enzymes used and their
effect on the pathogenesis of the disease.
A3. Identify the mode of action of
antiparasitic drugs at the molecular level.
A4. Explain how the resistance against
drugs occurs at the molecular level.
- 2
a10- Identify recent methods for
laboratory diagnosis of parasitic
infections with special emphasis
on molecular techniques.
a11- Discuss the prevention
strategies for control of vectors
and intermediate hosts
transmitting human parasites
especially newly emerging and re-
emerging parasites.
A5. Recognize the use of proteomic
analysis in diagnosis of parasitic diseases.
A6. Determine the role of genomic analysis
of parasites in diagnosis of parasitic
infections and select the appropriate method
of diagnosis for each parasite.
A7. Discuss how the proteomics can be
used in the control strategy against
parasites.
A8.Choose the appropriate strategy for
special cases.
C.
Professional
and Practical
Skills
c2- Analyze the statistical
methods needed to evaluate
diagnostic tests; including
sensitivity, specificity, positive
and negative predictive values.
.
c9- Apply computerized
information systems for recording,
analyzing, and reporting data.
c13- Prepare scientific articles
related to specialty and use
appropriate media for their
presentation.
C1. Determine the statistical tests needed
for evaluation of different tests.
c2. Interpret the results of statistics.
C3. Use information technology to access,
evaluate, report and interpret scientific data.
c4. Prepare scientific articles related to
genomes and proteomes.
c5. Use appropriate media for their
presentation (data show,video,etc……)
D. General &
Transferable
Skills
d3- Employ skills to be an efficient
staff member to perform teaching
tasks, plan and modify curricula,
assess and appraise junior staff.
d7- Demonstrate skills in
educating colleagues, students or
other health care professionals.
D1.Acquire skills to be an efficient staff
member.
d2. Acquire skills to perform teaching tasks.
D3.Plan and modify curricula.
D4. Assess and appraise junior staff.
D5. Practice educating colleagues, students
or other health care professionals while
presenting the seminar.
D6.Recognize and respect the views and
opinions of others.
d8- Communicate information
clearly both in written and oral
format.
d10- Retrieve information from all
sources ( printed, electronic,
communications etc…).
d13- Demonstrate an ability to use
methods of inquiry to collect and
interpret data in order to provide
information that would reform or
benefit practice.
d7.Co-operate in discussion groups to solve
scientific problems d8.Employ an evidence-based presentation
D8. Use different sources of information to
obtain data.
D9. Show competence in communicating
scientific findings.
D10. Acquire updated knowledge from various
sources.
d11. Appraise and systematize aquired
knowledge and present it to peers in a
professional manner.
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures self
learning
Practical/
Clinical
Small
group
discussion
Others
1. General Introduction to genomics.
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2. Contributions of proteomics in
parasitology.
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3. The role of functional genomics
analysis in development of vaccines.
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4- Impact of genomic analysis in
diagnosis of parasitic infections.
√
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Midterm
End of term 100 %
Distribution of Marks
Group discussion 20 %
Analysis of data 20 %
√
Presentation
Data show presentation 30 %
Continuous assessment 30 %
List of Textbooks and References
Lecture Notes
Course Text Books
-Genome Transcriptome and Proteome
Analysis by Alain Bernot
1. –Microbial Proteomics:Functionl
Biology of Whole Organisms by Ian
Humphery-Smith and Michael Hecker
Suggested Extra Reading
Links of Parasitology from the net
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
- BMC Genomics
- Molecular and Biochemical
Parasitology.
Course Instructor
Name: Prof. Dr. Shereen Farouk Mosalam
Signature:
Program Coordinator
Name: Prof. Dr. Mona El Temsahy
Signature:
Name: Prof. Dr. Lobna Abdel Aziz El Zawawy
Signature:
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga
Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical Parasitology
Course Information
Course Code: 05190910
Course Name: Seminar I( special topics)
Program in which the Course is Given: Doctor degree of Medical Parasitology
Number of Credit Hours 2 Theoretical Clinical/Practical
Course Aims: Seminar I includes a special topic: Electron microscopic studies of important
parasites such as Schistosoma spp., Leishmania spp., Toxoplasma gondii, Trichomanas vaginalis
and Giardia lamblia. It is carried by the students under supervision, to help them enforce their
power of information collection and presentation.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
By the end of the course
graduate must:
a1- Revise the diagnostic
morphology, life cycles, clinical
manifestations, diagnosis and
treatment of the studied parasites.
a8- Explain the basis for
therapeutic effects of antiparasitic
drugs and their mode of action.
By the end of course: electron
microscopic studies of different parasites,
the student will be able to:
A1- Describe the ultrastructural features of
different important parasites such as,
Schistosoma spp., and leishmania
spp.,…etc.
A2- Define the internal and external
morphological details of such parasites
through transmission and scanning electron
microscopic studies.
A3- Recognize the value of electron
microscopic studies of parasites to explain
the basic role of anti-parasitic drugs on their
- 2
morphology.
A4- Identify the mode of action of anti-
parasitic drugs on the external cuticle and
the internal structure of the studied
parasites.
B. Intellectual
skills
b4- Plan, undertake and evaluate
medical research in the field of
medical parasitology.
B1- Recognize the efficacy of chemicals,
drugs, vaccine, and different environmental
factors in disfiguring the parasitic structure
and loosing their function.
B2- Select the recent drug used to treat
different parasitic infections.
C. Professional
and Practical
Skills
c12- Design and employ research
relevant to medical and public
health problems in parasitic
diseases.
c13-Prepare scientific articles
related to specialty and use
appropriate media for their
presentation.
c14- Employ research studies that
add to the existing specialty
knowledge.
C1- Plan and prepare research studies about
the effect of recent advanced therapeutic
agents on ultrastructure of resistant
parasites to the ordinary effective drugs.
C2- Prepare scientific articles related to the
chosen topic (electron microscopic study of
different species of Leishmania, Schistosoma,
……etc).
C3- Select an appropriate media to facilitate
articles presentations.
C4- Plan and prepare research studies about
recent updates in ultra-structure morphology of
chosen parasites.
C5- Design and conduct a research project
and apply relevant research skills to
estimate the ultrastructure changes of
different parasites under the effect of drugs
or vaccines.
General &
transferable
skills
d1- Conduct individual
presentations at scientific
D1- Able to represent an evidence-based
presentation about the chosen topics.
conferences that are focused,
clear, and concise and
appropriately utilize time.
d10- Retrieve information from all
sources (printed, electronic,
communications etc…).
d13- Demonstrate an ability to use
methods of inquiry to collect and
interpret data in order to provide
information that would reform or
benefit practice.
d14- Use effectively and
efficiently information and
communication technology to
improve his/her professional
research ability and to collect
data.
D2- Able to get use of different methods of
presentations e.g data show, videos.
D3- Mange time effectively.
D4- Acquire updated knowledge from various
sources, appraise and systematize this
knowledge and present it to peers in a
professional manner.
D5- Use sufficient and efficient methods in
collection and interpretation of data.
D6- Use information and communication
technology to collect evaluate and interpret
scientific data.
D7- Demonstrate competence in
transferable skills (information and
communication technologies and
communication skills).
D. Ethics &
Attitudes
e3- Deal effectively with students,
colleagues whether juniors or
seniors and subordinates.
e4- Demonstrate positive work
habits, including punctuality,
dependability, and professional
appearance.
E1- Adopt to ethical principles in dealing
with colleagues and subordinates.
E2- Point to certain important positive work
habits including punctuality of the selected
and presenting items.
E3- Recognize the value of dependability in
data collection, and article presentation.
Teaching/Learning Methods
Course Content (Units/Topics)
Lectures self
learning
Practical/
Clinical
Small
group
discussion
Others
Electron microscopic studies of
Schistosoma spp.
✓
Electron microscopic studies of
Leishmania spp.
✓
Electron microscopic studies of
Toxoplasma gondii
✓
Electron microscopic studies of Giardia
lamblia
✓
Electron microscopic studies of
Trichomonas vaginalis
✓
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment
Mid-term
End of term 100 %
Distribution of Marks
Group discussion 20 %
Analysis of data 20 %
Data show presentation 30 %
Continuous assessment 30 %
List of Textbooks and References
Lecture Notes
Course Text Books
Roberts & Janovy, Foundations of Parasitology
Mullers & Baker, Medical Parasitology
Markell & Voge's, Medical Parasitology
Suggested Extra Reading
Links of Parasitology :
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
International journals for parasitology.
Journal of Parasitology.
√ Presentation
Course Instructor
Name: Prof. Dr. Iman Helmy
Signature:
Program Coordinator
Name: Prof. Dr. Mona Mohamed El-Temsahy
Signature:
Name: Prof. Dr. Lobna abdel Aziz El zawawy
Signature:
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga
Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical Parasitology
Course Information
Course Code: 05190909 Course Name: Vaccine trials in parasitic diseases
Program in which the Course is Given: Doctor Degree of Medical Parasitology
Number of Credit Hours Theoretical Clinical/Practical
Course Aims This course focusing on vaccine trials in parasitic diseases of global health importance such as schistosomiasis, leishmaniasis, trypanosomiasis, toxoplasmosis and malaria. It aims at studying the specific pathogenic characters and pathogenesis of parasites, immunological host response to parasites, different types and recent approaches of vaccines tried against parasites in addition to their applicability, advantage and disadvantages.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
Graduate must have sufficient
knowledge & understanding of:
a6- Recognize the pathogenic
characters of parasites and how they
produce tissue damage.
a7- Explain at the cellular and
molecular levels the concept of
pathogenesis and the host-parasite
interactions.
By the end of course: vaccination trials in
parasitic disease, the student will be able
to: A1- Recognize the pathogenic characters of
parasites of global heath importance such as,
Schistosoma, Leishmania, Trypanosoma,
Toxoplasma gondii and Plasmodium species
and how they produce tissue damage.
A2- Describe the immunological host response
to parasites of global heath importance such as,
Schistosoma, Leishmania, Trypanosoma,
Toxoplasma gondii and Plasmodium species.
A3- Defines the main immunological
mechanism responsible for host protection
against parasites of global heath importance
such as, Schistosoma, Leishmania,
Trypanosoma, Toxoplasma gondii and
2
a16- Identify the recent approaches
in vaccine development.
Plasmodium species.
A4- Identify the different types and recent
approaches of vaccines tried against parasites
of global heath importance such as,
Schistosoma, Leishmania, Trypanosoma,
Toxoplasma gondii and Plasmodium species.
A5-Recognize the advantage and disadvantages
of different vaccines tried against parasites of
global heath importance such as, Schistosoma,
Leishmania, Trypanosoma, Toxoplasma gondii
and Plasmodium species.
A6- Describe the state of the art for vaccination
trials for parasites of global heath importance
such as, Schistosoma, Leishmania,
Trypanosoma, Toxoplasma gondii and
Plasmodium species.
C.Professional
and Practical
Skills
c1- Use a systematic approach for
data collection and recording.
C13-Prepare scientific articles
related to specialty and use
appropriate media for their
presentation.
C1-Collect data from different sources about
vaccination trials for parasites of global health
importance such as, Schistosoma, Leishmania,
Trypanosoma, Toxoplasma gondii and
Plasmodium species.
C 2- Plan and prepare for a review article about
vaccination trials for schistosomiasis.
C3- Plan and prepare for a review article about
vaccination trials for leishmaniasis.
C4- Plan and prepare for a review article about
vaccination trials for trypanosomiasis.
C5- Plan and prepare for a review article about
vaccination trials for Toxoplasmosis.
C6- Plan and prepare for a review article about
vaccination trials for Malaria.
D. General &
Transferable
Skills
d1- Conduct individual presentations
at scientific conferences that are
focused, clear, and concise and a
appropriately utilize time.
d8- Communicate information
clearly both in written and oral
format.
D1- Conduct indindividual presentation at
scientific conferences about the state of art of
vaccination in schistosomiasis which should be
clear, concise and appropriately use time.
D2- Conduct indindividual presentation at
scientific conferences about the state of art of
vaccination in leishmaniasis which should be
clear, concise and appropriately use time.
D3- Conduct indindividual presentation at
scientific conferences about the state of art of
vaccination in trypanosomiasis which should be
clear, concise and appropriately use time.
D4- Conduct indindividual presentation at
scientific conferences about the state of art of
vaccination in toxoplasmosis which should be
clear, concise and appropriately use time.
D5- Conduct indindividual presentation at
scientific conferences about the state of art of
vaccination in malaria which should be clear,
concise and appropriately use time.
D6- Apply effectively & efficiently different
methods of presentations e.g. data show,
videos
D7- shows skills in preparing data show
presentation for the previous topics.
D8- Communicate effectively using written and
oral format to show the various data collected
for the previous topics.
D9- Communicate effectively as a lecturer to
present the state of the art of vaccination trials
for parasites of global heath importance such
as, Schistosoma, Leishmania, Trypanosoma and
Plasmodium.
D10- Demonstrate skills in collecting data about
vaccination trials of vaccination trials for
_____________
E-Ethics &
Attitudes:
d10- Retrieve information from all
sources ( printed, electronic,
communications etc…).
d11- Verify the accuracy of scientific
material on basis of best evidence in
medicine and in practice.
d13- Demonstrate an ability to use
methods of inquiry to collect and
interpret data in order to provide
information that would reform or
benefit practice.
e4- Demonstrate positive work
habits, including, punctuality,
dependability & professional
appearance.
parasites of global health importance such as
Schistosoma, Leishmania, Trypanosoma and
Plasmodium from all sources.
D11-Retrieve relevant parasitological updates
from reliable scientific resources.
D12- Show accuracy in collecting scientific data,
and focusing on the most recent data for the
previous topics
D13- Use sufficient and effective methods in
collection and interpretation of data.
D14-Use information technology to access,
evaluate and interpret scientific data.
E1- Respect timing required for data collection.
E2- be punctuate in presenting article reviews
and data show presentation
E3-respect the views and opinions of others.
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures Self
learning
Practical/
Clinical
Small
group
discussion
Others
Vaccination trials in schistosomiasis √
Vaccination trials in leishmaniasis
√
Vaccination trials in trypanosomiasis √
Vaccination trials in toxoplasmosis √
Vaccination trials in malaria √
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment
Mid-term
End of term 100 %
Distribution of Marks
Written Exam 100 %
Practical/Clinical Exam
Others
List of Textbooks and References
Lecture Notes
Course Text Books
- Beaver & Jung, Clinical Parasitology
- Garcia, Diagnostic Medical Parasitology
- Bell, Tropical medicine
Suggested Extra Reading
Links of Parasitology :
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
▪ Vaccine
▪ Journal infectious diseases
▪ Journal immunology
▪ Infection and immunity
√
Course Instructor
Name: Prof. Dr. Maha Eissa
Signature:
Program Coordinator
Name: Prof. Dr. Mona el -Temsahy
Signature:
Name: Prof. Dr. Lobna El Zawawy
Signature:
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga
Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical parasitology
Course Information
Course Code: 05190901
Course Name: Advanced medical helminthology
Program in which the Course is Given; Doctor degree of Medical Parasitology.
Number of Credit Hours: 3 Theoretical Clinical/Practical
Course Aims; The course of advanced medical helminthology is discussing Phylum Platyhelminthes and Phylum Nematoda, regarding all advanced subjects and parasites.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
By the end of the program the
PG students will be able to:
a2- Recognize updates in morphology, biology and life cycles of parasites and their relevance for human health. a7- Explain at the cellular and molecular levels the concept of pathogenesis and the host-parasite
By the end of the advanced medical helminthology course the student will be able to: A1- Outline the new scientific taxonomy for helminthes (Platyhelminthes & Nematodes) if any. A2- Recognize morphological characters of important helminthes and re-emerging parasites. A3- Recognize different reservoirs, intermediate hosts and vectors of helminthes. A4-Describe the biology and interrelationships between worms and their hosts. A5- Describe ultra-structure and morphological identification of different stages of the worms. A6- Recognize the main pathological lesions caused by worms by the usual pathological examination and by application of electron
1 2
interaction. a9- Identify pitfalls and resistance of current therapy regimens and the role of recently discovered antiparasitic drugs. a10- Identify recent methods for laboratory diagnosis of parasitic infections with special emphasis on molecular techniques. a11- Discuss the prevention strategies for control of vectors and intermediate hosts transmitting human parasites especially newly emerging and re-emerging parasites. a13- Trace recent advances in the field of medical parasitology and apply this knowledge in the diagnosis of parasitic infections. a16- Identify the recent approaches in vaccine development.
microscopic studies. A7- Associate the pathogenesis caused by the studied worms with the host immune response. A8- Relate the pathogenesis with the clinical manifestations of the studied helminths. A9- Explain the therapeutic effects of antihelminthic drugs and their mode of action. A10- Define the side effects, contraindications of antihelminthic drugs. A11- Recognize the parasites which develop resistance to common antihelminthic therapy like praziquantel A12- Select laboratory techniques for assessment of humoral and cellular immunity. A13- Recognize new advanced techniques regarding molecular ones in diagnosis of endemic and common infectious helminthic infections. A14- Define the intermediate host and vectors of helminthes and their impact in their transmission. A15- Recognize the hazards of people's habits which contribute to spread of infections caused by helminths. A16- Identify the preventive strategies already applied in the field of control of helminthic infections. A17- Recognize the new strategies for prevention and control of helminthic infections. A18- Identify recent molluscicides and methods of their application. A19- Recognize what is new in medical heminthology specially re- emerging parasite and imported ones. A20- Recognize methods of diagnosis and treatment of re-emerging and imported parasites. A21- Recognize the classical lines in treatment & new drugs developed to overcome resistance strains in schistosoma.
A22- Recognize the development of vaccines to schistosoma and filarial infection. A23- Trace the findings in genome projects of Schistosoma spp. and filarial worms.
B. Intellectual
skills
b4- Plan, undertake and evaluate medical research in the field of medical parasitology.
B1- Recognize the concepts behind research in medical helminthology and the need for continuous development of diagnostic and preventive methods.
B2-Practice planning, undertaking and evaluating medical and clinical research in the field of medical helminthology.
B3- Evaluate new diagnostic techniques and compare them with old ones before introducing them into the lab.
C.Professional
and Practical
Skills
c7- Develop new skills or procedures for new situations such as emerging and re-emerging parasitic diseases. c9- Apply computerized information systems for recording, analyzing, and reporting data. c12- Design and employ research relevant to medical and public health problems in parasitic diseases.
C1- Employ recent staining techniques for different stages of helminthic parasites .
C2- Identify staining patterns, morphologies and arrangements under the microscope. C3- Apply the safety precautions in the lab. C4- Perform and interpret commonly used immunological techniques such as ELISA and immunodiffusion. C5- Employ some advanced molecular methods such as nucleic acid extraction, PCR amplification and transformation.
C6- Use information technologies to access, analyze record and report data. C7- Retrieve information from various available sources, appraise and systematize this knowledge. C8- Employ research studies that add to the existing specialty knowledge. C9- Design research that solve common community problems related to helmintic infections.
D. General
Skills
d1- Conduct individual presentations at scientific conferences that are focused, clear, and concise and appropriately utilize time. d3- Employ skills to be an efficient
D1- Prepare scientific articles related to specialty with clear and concise knowledge. D2- Use appropriate media for their presentation. D3- Develop appropriate means of estimating and monitoring recourses and the use of time. D4- Demonstrate skills in educating colleagues,
staff member to perform teaching tasks, plan and modify curricula, assess and appraise junior staff.
students or other health care professionals. D5- Verify the accuracy of scientific material on basis of best evidence in medicine and in practice. D6- Perform self appraisal and seek continuous learning.
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures self
learning
Practical/
Clinical
Small
group
discussion
Others
1- Advances in classification,
ultrastructural and diagnosis of
Platyhelminthes.
✓ ✓ √
2- Advances in classification,
ultrastructural and diagnosis of
Nematodes.
✓ ✓ ✓
3- Case reports of rarely infectious
and re-emerging helminthic
infections.
✓ ✓ ✓
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment
Mid-term
End of term 100 %
Distribution of Marks
Written Exam 70 %
Practical/Clinical Exam 20 %
Others 10 %
✓ ✓
✓
✓ ✓
List of Textbooks and References
Lecture Notes
Peters & Pasval, Atlas of Tropical Medicine
and Parasitology
Course Text Books
• Beaver & Jung, Clinical parasitology.
• Garcia, Diagnostic parasitology.
• Bell, Tropical Medicine
• Paniker, Text book of Medical
parasitology.
Suggested Extra Reading
Links of Parasitology from the internet
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
- American Journal of Parasitology
- Lancet
- Parasitology Today
- Journal of newly emerging infectious diseases.
Course Instructor
Name: Prof. Dr. Eman Dorry Hussein
Signature:
Program Coordinator
Name: Prof. Dr. Mona El-Temsahy
Signature:
Name: Prof. Dr. Lobna El Zawawy
Signature:
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga
Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical Parasitology
Course Information
Course Code: 05190905
Course Name: Medical entomology II
Program in which the Course is Given :Doctorate of Medical Parasitology
Number of Credit Hours: 3 Theoretical Clinical/Practical
Course Aims Medical Entomology II course focuses on the knowledge about different types of Crustaceans, Arachnids
(Scorpionida, Acarina), Insecta (Bugs, Lice, and Fleas, Mosquitoes, Flies), their behavior, diseases,
transmitted or caused by them, their importance in relation to human health and control.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program
matrix) Course ILOs
A. Knowledge
and
Understanding
By the end of the course graduate
must have sufficient knowledge &
understanding of:
a1- Revise the diagnostic morphology,
life cycles, clinical manifestations,
diagnosis and treatment of the studied
parasites.
By the end of Entomology II course 1;
the student will be able to:
A1- Describe the diagnostic morphology
of different life cycle stages of the
Crustaceans, Arachnids, Insecta of
medical importance and to differentiate
between each order.
A2- Identify the habitat of different stages
of the studied arthropods of medical
importance belonging to these classes.
A3- Understand the biology and life
cycle of the studied arthropods.
A4- Know the different diagnostic
techniques which could allow proper
diagnosis of the diseases caused by the
studied arthropods.
1 2
a2- Recognize updates in morphology,
biology and life cycles of parasites and
their relevance for human health.
a3- Describe the mode of infection of
different organisms transmitted by
parasites among humans.
a4- Identify the role played by
intermediate hosts and vectors in
disease transmission.
a5- Define terms used in describing
aspects of parasitic pathogenesis.
A5- Select the proper therapeutic
regimen for treating diseases caused by
these arthropods.
A6- Identify the updates in the diagnostic
morphology of different Crustaceans,
Arachnids, Insecta of medical
importance.
A7- Recognize the updates in the biology
of different life cycle stages of these
arthropods.
A8- Recognize the updates in the life
cycles of these arthropods.
A9- Correlate between updated
knowledge about these arthropods and
their relevance to human health.
A10- Identify the diseases transmitted
by the medically importance
Crustaceans, Arachnids, Insecta.
A11- Recognize how people get
infection by such diseases.
A12- Comprehend the role played by
Crustaceans, Arachnids, Insecta of
medical importance as vectors in disease
transmission whether parasitic,
bacterial, viral or rickettsial diseases.
A13- Identify and classify the diseases
caused by Crustaceans, Arachnids,
Insecta of medical importance: specific
diseases (scabies, tungiasis, pediculosis,
myiasis), allergic reactions or due to
toxin produced by these arthropods.
A14- Recognize the terms used in
describing the main pathological lesions
caused by the various life cycle stages
of Arachnids and Insecta of medical
importance.
a11- Discuss the prevention strategies
for control of vectors and intermediate
hosts transmitting human infectious
agents especially newly emerging and
re-emerging parasites.
a12- Recognize the hazards of various
customs and habits applied by people
which contribute to the spread of
parasites.
a13- Trace recent advances in the field
of medical Parasitology and apply this
knowledge in the diagnosis of parasitic
infections.
a14- Describe the nature of parasitic
infections in the immunocompromized
host (opportunistic parasites).
A15- Discuss the requited preventive
methods against various Crustaceans,
Arachnids, Insecta responsible for
transmitting human infectious agents.
A16- Understand the control measures
that could be used against these
arthropods responsible for transmitting
human infectious agents especially
newly emerging and re-emerging
parasites.
A17- Comprehend the consequences of
different customs and habits applied by
people which contribute to the spread of
diseases caused by or transmitted by
Crustaceans, Arachnids, Insecta of
medical importance.
A18- State the recent advances in the
field of medical entomology especially
that related to Crustaceans, Arachnids,
Insecta.
A19- Recognize the recent methods in
diagnosis of various infections
transmitted by these arthropods.
A20- Know the recent convenient
techniques can be used in diagnosis of
various diseases caused by these
arthropods.
A21- Understand the course, hazards
and outcome of infections caused by
Arachnids and Insecta in
immunocompromized host.
B. Intellectual
skills
b1- Interpret the results of diagnostic
techniques.
b4- Plan, undertake and evaluate
medical research in the field of medical
Parasitology.
B1- Infer the interpretations of
diagnostic Sarcoptes scabieii from skin
scrapping and skin sections.
B2- Interpret the results of examination
of different collected samples containing
insects of medical importance.
B3- Recognize the need for continuous
development of effective preventive
measures against Crustaceans,
Arachnids, Insecta of medical
importance and accomplishes research
about this topic.
B4- Practice planning, undertaking and
evaluating medical research in the field
of medically important Crustaceans,
Arachnids, Insecta.
B5- Evaluate data collected from
research in the field of these arthropods.
C. Professional
and Practical
Skills
c12- Design and employ research
relevant to medical and public health
problems.
c14- Employ research studies that add
to the existing specialty knowledge.
C1- Conduct research studies on the
importance of diseases caused and
transmitted by Crustaceans, Arachnids
and Insecta and clarify their impact on
the community health.
C2- Propose research regarding the
hazard posed by different Crustaceans,
Arachnids and Insecta of medical
importance in transmission and
production of diseases.
C3- Plan further research studies to add
to the knowledge of various preventive
and control measures to Crustaceans,
Arachnids, Insecta of medical
importance.
D. General
Skills
d1- Conduct individual presentations at
scientific conferences that are focused,
clear, and concise and appropriately
utilize time.
D1- Accomplish individual
presentations about hazards of
Crustaceans, Arachnids and Insecta of
medical importance on the community
with clear and simple knowledge.
D2- Present the prepared topics at
scientific conferences with a clear
concise statement and appropriately
utilize time.
d2- Communicate effectively with
colleagues giving advice, instructions
and professional opinions.
d3- Employ skills to be an efficient
staff member to perform teaching tasks,
plan and modify curricula, assess and
appraise junior staff.
d7- Demonstrate skills in educating
colleagues, students or other health care
professionals.
d10- Retrieve information from all
sources ( printed, electronic,
communications etc…).
D3- Communicate effectively with
colleagues from various departments
who could face medical problems posed
by or conveyed by Crustaceans,
Arachnids and Insecta of medical
importance, through giving advice
professional opinions about their
diagnosis, prevention and control.
D4- Update recent skills required to be
an efficient staff member to perform
teaching tasks in the field of
Crustaceans, Arachnids and Insecta of
medical importance.
D5- Display recent skills required to be
an efficient staff member to plan and
modify curricula in the field of these
arthropods.
D6- Apply recent skills required to be an
efficient staff member to assess and
appraise junior staff.
D7- Display skills in educating
colleagues in the field of Crustaceans,
Arachnids, and Insecta of medical
importance.
D8- Exhibit skills in educating students
in the field of these arthropods.
D9- Show skills in educating health care
professionals about hazards of these
arthropods.
D10- Gain updated information about
Crustaceans, Arachnids and Insecta of
medical importance from all sources
(printed, electronic, communications
etc…).
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures self
learning
Practical/
Clinical
Small
group
discussion
Others
1- Introduction to Entomology 1 ✓ ✓
2- Crustacea (Cyclops) ✓ ✓ ✓
3- Arachnida:
Order: Scorpionida
Order: Acarina
✓ ✓ ✓
4-Insecta: Class Anoplura ✓ ✓ ✓
5- Insecta: Class Hemiptera ✓ ✓ ✓
6- Insecta: Class siphonaptera ✓ ✓ ✓
Please check (✓) the appropriate method.
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Schedule of Assessment
Mid-term
End of term 100 %
Distribution of Marks
Written Exam 70 %
Practical/Clinical Exam 30 %
Others
List of Textbooks and References
Lecture Notes - Wallace Peters, A colored Atlas of Arthropods in Clinical Medicine
Course Text Books
- Service, Medical Entomology for Students, 2nd ed.2000
- Goddard, Arthropods of Medical Importance2nd ed. 1996
-Beaver & Jung, Clinical Parasitology,9th ed.1984
-Garcia, Diagnostic Medical Parasitology5th ed.2007
Course Code: 05190907 Course Name: Molecular Parasitology II
Program in which the Course is Given: Doctor degree of Medical Parasitology
Number of Credit Hours: 2 Theoretical Clinical/Practical
Course Aims: The course of Molecular Parasitology II aims at informing students to the
importance of molecular and cellular interactions between different parasites and their hosts. The
course aims to encourage the students to access information from different sources and to
communicate the principles in a well-organized way.
Intended Learning Outcomes (ILOs)
Program ILO (refer to program matrix) Course ILOs
A. Knowledge and Understanding
By the end of the course the graduate must be able to: a7- Explain at the cellular and molecular levels the concept of pathogenesis and the host-parasite interactions.
a10- Identify recent methods for laboratory
diagnosis of parasitic infections with special
emphasis on molecular techniques._
By the end of Molecular Parasitology course the student will be able to: A1- Recognize how the host can interact with the parasite. A2- Understand in details the molecular and cell biology of certain protozoan parasites. A3- Understand in details the metabolic novelties in parasites and their potential as novel drug targets. A4- Recognize the molecular tests used in the diagnosis of parasitic diseases. A5- Identify the recent immunological tests used specially at the molecular and genetic levels.
2
B. Intellectual skills
b1- Interpret the results of direct parasitological techniques.
B1- Determine the most suitable diagnostic test for a certain clinical presentation. B2- Correlate the results of molecular techniques with the clinical picture. B3- Correlate the results of molecular techniques with the line of treatment.
C. Professional and Practical Skills
c2- Analyze the statistical methods needed
to evaluate diagnostic tests; including
sensitivity, specificity, positive and
negative predictive values.
c3- Perform competently sample handling including: specimen collection and transport, sample handling and storage in the laboratory and disposal of high risk samples and containment. c6- Perform indirect tests for detection of:
•Nucleic acid using molecular amplification
methods.
c7- Develop new skills or procedures for new situations such as emerging and re-emerging parasitic diseases.
C1- Determine the statistical tests needed for evaluation of different molecular tests. C2- Interpret the results of statistics. C3- Recognize the risk factors that may occur during collection of different specimens. C4- Choose the appropriate method for transport. C5- Decide the safe method in disposal of the samples not needed. C6- Evaluate the risks imposed during professional laboratory work C7- Predict indirect tests for detection of nucleic acid of the parasites as DNA probe and polymerase chain reaction techniques (PCR). C8- Utilize properly different laboratory equipments used in serological and molecular diagnosis of parasitic infections. C9- Develop and evaluate new methods or procedures for diagnosis of parasitic infections and comparing them with the gold standard methods used for diagnosis. C10- Carry out specialized skills in: advanced diagnostic molecular and immunological aspects of parasitic infections. C11- Use information technology to collect, analyze, record and report
c.9- Apply computerized information systems for recording, analyzing, and reporting data.
data C12- Utilize appropriate computer software in recording, analyzing, and reporting scientific data in a parasitology lab.
D. General Skills
d1- Conduct individual presentations at scientific conferences that are focused, clear, and concise and appropriately utilize time. d13- Demonstrate an ability to use methods of inquiry to collect and interpret data in order to provide information that would reform or benefit practice.
D1- Participate in seminars, conferences and workshops for further development of specialty. D2- Employ skills to be concise in his presentation and appropriately utilize time. D3- Able to get use of different methods of presentations e.g data show ,videos D4- Retrieve information from all sources (printed, electronic, communications etc…) to know recent methods in diagnosis. D5- Acquire updated knowledge from various sources, appraise and systematize this knowledge and present it to peers in a professional manner. D6- Use self-learning methods in practice information gathering and information technology.
e5- Appraise principles of confidentiality with all information transmitted both during and outside a patient encounter.
E1- Collect data confidentiality and apply all medical research ethics.
Course Content (Units/Topics)
Teaching/Learning Methods
Lectures self
learning
Practical/
Clinical
Small
group
discussion
Others
Parasite molecular biology:
- Parasite genomics
- RNA processing in parasites
Transcription
- Post-transcriptional regulation
- Antigenic variation
(Trypanosomes)
- Influence of host genetics on
host resistance
- Genetic and genomic
approaches to study virulence
✓
✓
Biochemistry and Cell biology:
Protozoa: -Energy metabolism:
Anaerobic protozoa
Aerobic protists
Apicomplexa
-Amino acid and protein metabolism
-Purine and pyrimidine transport and
metabolism
-Parasite Glycobiology
GPI anchors (Trypanosomes)
Protein glycosylation: Glycans and
virulence
Intracellular signaling I& II
-Cell invasion and intracellular survival
Plasmodium
Toxoplasma gondii
Intestinal coccidians
Leishmania
-Plastids, hydrogenosomes and
mitochondria
✓
✓
Advanced topics in molecular
Parasitology:
-Transposable elements in parasites
✓ ✓
-Remodelling of host erythrocyte by
Plasmodium proteins -Host-paarsite interactions at the site of
the insect vector bite in protozoan
diseases
-Cell division of apicomlexan parasites
-Vesicular traffic in Toxoplasma
infection
Medical applications: -Parasite detection and diagnosis
-Recent molecular diagnostic
techniques for protozoa
-Epidemiology and clinical
manifestations
-Treatment and vaccines
-Drug resistance
✓
✓
✓
Please check (✓) the appropriate method
Student Assessment
Methods of Assessment
Essay Objective questions
Case OSCE/OSPE
Assignment Logbook fulfillment
Others
Mid term
End of term 100 %
Distribution of Marks
Written Exam 70 %
Practical/Clinical Exam - %
Others: 30 %
Assignment 15 %
Oral exam 15 %
✓ ✓
✓ ✓
Oral exam
List of Textbooks and References
Lecture Notes
Parasitology notes
Course Text Books Marr JJ, Nilson TW and Komuniecki RW,
Molecular Medical Parasitology
Suggested Extra Reading
Links of Parasitology from the net
www. Dpd.cdc.gov/dpdx. Parasites and health
Journals and Periodicals, others
International Journal of Parasitology
Molecular Microbiology
Molecular cell Biology
Course Instructor
Name: Prof. Dr. Eman Rafaat
Signature:
Program Coordinator
Name: Prof. Dr. Mona El-Temsahy
Signature:
Name: Prof. Dr. Lobna abdel Aziz El Zawawy
Signature:
Program Director (Head of Department)
Name: Prof. Dr. Iman Abo El Naga
Signature:
Course Specifications
University: Alexandria
Faculty: Medicine
Department: Medical Parasitology
Course Information
Course Code: 05190903
Course Name: Blood and tissue protozoa
Program in which the Course is Given: Doctor degree of Medical Parasitology
Number of Credit Hours 3 Theoretical Clinical/Practical
Course Aims: A course in blood and tissue protozoa discusses the different protozoa affection the tissue and the blood including mastigophora, coccidian, sporozoa as regards their geographical distribution, morphology, life cycle, clinical picture, complications, impact on human health and means of control. All newly emerging protozoa are in this subject.