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CCNT2 20,895 8,305 8,016 1,450 2,528 65 <1.0E-300 cFOS 14,404 2,943 2,914 213 2,075 55 <1.0E-300 cFOS 14,404 6,001 5,969 76 1,246 39 <1.0E-300cFOS 14,404 2,966 2,881 521 2,279 58 <1.0E-300 CCNT2 20,895 9,303 9,217 673 2,015 53 <1.0E-300 USF1 21,313 6,413 6,384 82 869 27 <1.0E-300CHD2 6,932 3,109 3,076 556 1,605 41 <1.0E-300 E2F6 20,609 11,024 10,944 799 2,462 65 <1.0E-300 E2F6 20,609 6,674 6,617 85 619 19 <1.0E-300cMYC 13,693 6,506 6,300 1,139 2,248 57 <1.0E-300 POL2 23,586 11,589 11,497 839 2,714 72 <1.0E-300 POL2 23,586 5,775 5,706 73 587 18 <1.0E-300E2F4 9,862 7,163 7,025 1,271 2,615 67 <1.0E-300 ORC2 15,401 4,337 4,258 311 1,123 30 <1.0E-300 TBP 14,496 3,516 3,494 45 471 15 <1.0E-300E2F6 20,609 9,516 9,187 1,662 3,037 78 <1.0E-300 ELF1 17,951 4,718 4,692 342 1,198 32 <1.0E-300 E2F4 9,862 1,589 1,587 20 384 12 <1.0E-300
HMGN3 18,815 8,880 8,612 1,558 2,695 69 <1.0E-300 HMGN3 18,815 9,921 9,854 719 2,167 57 <1.0E-300 USF2 1,623 517 517 7 242 8 <1.0E-300POL2 23,586 10,316 9,954 1,800 3,347 86 <1.0E-300 cMYC 13,693 7,222 7,138 521 1,919 51 <1.0E-300 HMGN3 18,815 4,691 4,655 59 503 16 2.5E-300
ps2-POL2 29,410 9,741 9,466 1,712 3,126 80 <1.0E-300 TBP 14,496 9,305 9,206 672 2,499 66 <1.0E-300 CCNT2 20,895 8,724 8,639 110 649 20 1.9E-297TBP 14,496 8,261 8,053 1,456 2,912 74 <1.0E-300 ps2-POL2 29,410 10,436 10,386 758 2,546 67 <1.0E-300 CHD2 6,932 1,206 1,205 15 302 9 1.9E-290
HEY1 9,229 4,549 4,475 809 1,695 43 2.4E-285 E2F4 9,862 7,287 7,230 528 2,153 57 <1.0E-300 cMYC 13,693 5,047 4,985 64 478 15 2.5E-261ORC2 15,401 3,522 3,404 616 1,286 33 5.3E-199 MAX 6,402 2,667 2,641 193 823 22 <1.0E-300 MAX 6,402 2,011 2,002 26 321 10 4.7E-243
BHLHE40 16,358 4,341 4,268 772 1,455 37 4.4E-179 CHD2 6,932 3,296 3,283 240 1,371 36 <1.0E-300 ELF1 17,951 7,935 7,866 100 539 17 5.4E-225ELF1 17,951 3,936 3,852 697 1,346 34 3.3E-173 HEY1 9,229 5,400 5,352 391 1,547 41 <1.0E-300 ps2-POL2 29,410 4,844 4,819 62 431 13 1.4E-222MAX 6,402 2,534 2,500 452 1,006 26 1.8E-171 GABP 5,025 2,915 2,912 212 835 22 4.2E-289 ORC2 15,401 9,013 8,890 114 562 18 4.0E-218
cJUN 18,480 3,394 3,277 593 1,138 29 1.4E-138 BHLHE40 16,358 5,170 5,149 376 1,132 30 5.3E-286 HEY1 9,229 2,372 2,340 30 296 9 1.9E-193TFIIF 10,662 5,241 5,127 927 1,540 39 5.2E-131 GTF2B 2,475 1,594 1,576 115 588 16 4.6E-266 BHLHE40 16,358 7,309 7,291 93 468 15 2.2E-182
GTF2B 2,475 1,445 1,424 258 620 16 1.3E-118 cJUN 18,480 3,733 3,703 270 914 24 6.9E-264 Cjun 18,480 10,485 10,399 133 526 16 6.6E-161USF1 21,313 2,584 2,535 458 912 23 3.1E-117 USF1 21,313 2,746 2,738 200 754 20 4.1E-246 HDAC8 9,860 5,618 5,473 70 335 10 4.4E-123GABP 5,025 2,765 2,741 496 959 25 2.7E-115 TFIIF 10,662 6,203 6,134 448 1,184 31 2.0E-245 SP1 5,576 2,247 2,228 28 204 6 9.0E-106
HDAC8 9,860 2,793 2,672 483 939 24 5.2E-114 HDAC8 9,860 2,412 2,387 174 663 18 1.6E-216 EGR1 19,094 8,480 8,427 108 386 12 3.4E-103YY1 5,250 2,534 2,510 454 878 22 2.9E-104 YY1 5,250 3,107 3,092 226 749 20 2.1E-206 GATA2 9,025 5,927 5,876 75 314 10 6.2E-100
CEBPB 44,168 2,972 2,824 511 910 23 1.0E-85 NRF1 3,328 2,181 2,174 159 595 16 2.2E-189 TAL1 24,841 15,970 15,864 203 545 17 2.2E-98BRD4 10,746 3,203 3,139 568 982 25 2.7E-85 BRD4 10,746 3,779 3,718 271 791 21 4.4E-181 ZBTB7A 8,031 3,793 3,773 48 235 7 2.5E-87NRF1 3,328 2,170 2,154 390 742 19 1.1E-82 MXI1 3,020 1,592 1,588 116 466 12 1.2E-159 SIX5 3,397 332 330 4 81 3 2.5E-77MXI1 3,020 1,390 1,383 250 542 14 1.6E-81 SIN3A 2,701 1,180 1,171 85 380 10 2.1E-145 GTF2B 2,475 455 452 6 88 3 2.1E-74
TFIIIC 10,004 2,310 2,229 403 732 19 6.7E-71 CEBPB 44,168 3,215 3,161 231 655 17 2.8E-141 GABP 5,025 1,213 1,212 15 128 4 6.3E-74SP1 5,576 324 319 58 191 5 7.4E-63 USF2 1,623 602 602 44 255 7 3.7E-128 TFIIF 10,662 3,330 3,308 42 197 6 5.6E-70
USF2 1,623 547 547 99 268 7 1.1E-62 TFIIIC 10,004 2,765 2,714 198 532 14 4.0E-103 BRD4 10,746 5,081 5,039 64 240 8 1.2E-66SIN3A 2,701 1,137 1,129 204 421 11 1.6E-55 EGR1 19,094 3,194 3,177 232 564 15 1.2E-91 CEBPB 44,168 11,542 11,470 146 387 12 2.0E-66CTCF 46,476 4,790 4,537 821 1,088 28 1.2E-54 GTF2F1 885 415 415 30 156 4 1.3E-69 STAT2_30m 2,514 1,593 1,580 20 128 4 2.0E-60EGR1 19,094 2,549 2,503 453 748 19 1.9E-53 ATF3 939 486 486 35 163 4 2.2E-64 HDAC2 8,831 4,751 4,700 60 219 7 3.4E-59
GTF2F1 885 368 368 67 175 4 6.7E-39 SP1 5,576 494 491 36 159 4 2.0E-60 PU1 25,479 8,488 8,424 108 302 9 7.6E-57TAL1 24,841 1,641 1,596 289 494 13 1.7E-38 ZBTB7A 8,031 2,459 2,443 178 413 11 5.8E-60 NRF1 3,328 478 478 6 74 2 3.1E-55
NELFE 1,136 317 316 57 156 4 3.1E-37 CTCF 46,476 6,027 5,919 432 763 20 4.2E-59 GATA1 3,182 1,672 1,665 21 120 4 2.3E-51THAP1 1,606 427 425 77 176 4 1.4E-29 NELFE 1,136 338 337 25 125 3 3.3E-55 FOSL 11,393 6,788 6,742 86 246 8 1.7E-47
ZBTB7A 8,031 1,864 1,840 333 502 13 2.0E-24 THAP1 1,606 501 500 36 146 4 2.8E-49 ATF3 939 78 78 1 35 1 4.6E-45ATF3 939 496 495 90 181 5 9.2E-23 JUND 945 323 323 24 114 3 6.6E-48 CTCF 46,476 6,067 6,031 77 224 7 1.8E-44
BRG1 11,209 830 797 144 257 7 1.0E-22 SETDB1 8,379 1,032 1,031 75 209 6 3.9E-42 BRG1 11,209 5,408 5,363 68 196 6 5.0E-38SPT5 1,839 249 245 44 108 3 3.6E-21 SIX5 3,397 416 415 30 119 3 1.6E-39 NFE2 3,477 2,223 2,213 28 118 4 1.1E-37JUND 945 308 307 56 124 3 5.3E-20 SPT5 1,839 277 276 20 94 2 2.9E-38 MEF2A 10,209 4,389 4,337 55 170 5 1.1E-36
SETDB1 8,379 997 979 177 287 7 1.5E-18 BRG1 11,209 1,770 1,713 125 270 7 1.2E-33 ETS1 2,607 1,157 1,153 15 82 3 4.1E-35INI1 8,061 592 568 103 180 5 1.9E-15 TAL1 24,841 2,681 2,660 194 363 10 1.0E-31 BCLAF 6,616 2,758 2,712 35 127 4 7.1E-35
SIX5 3,397 431 427 77 142 4 2.7E-14 STAT2_30m 2,514 578 576 42 130 3 2.3E-31 MAFK 17,914 6,545 6,532 83 212 7 1.2E-33STAT2_30m 2,514 482 480 87 150 4 1.8E-12 NFE2 3,477 439 437 32 104 3 2.5E-27 MXI1 3,020 517 517 7 55 2 1.0E-32
NFE2 3,477 380 375 68 122 3 1.1E-11 INI1 8,061 1,369 1,325 97 209 6 4.0E-26 YY1 5,250 791 791 10 66 2 1.4E-32ETS1 2,607 272 268 48 88 2 5.2E-09 ZNF263 8,128 1,444 1,438 105 212 6 7.9E-23 STAT2_6h 2,174 1,153 1,149 15 78 2 4.1E-32
RPC155 2,075 282 278 50 87 2 1.0E-07 TR4 612 237 237 17 65 2 4.3E-21 TFIIIC 10,004 3,175 3,164 40 127 4 1.3E-28TR4 612 241 241 44 78 2 7.6E-08 ETS1 2,607 460 458 33 90 2 5.9E-18 NR4A1 5,514 1,709 1,685 22 85 3 6.6E-26
ZNF263 8,128 1,327 1,298 235 299 8 3.8E-06 NR4A1 5,514 502 500 36 89 2 6.0E-15 P300 2,969 1,040 1,038 13 63 2 1.2E-23ZBTB33 4,530 253 251 45 74 2 1.0E-05 PU1 25,479 1,454 1,439 105 188 5 6.7E-15 TAF7 4,536 1,254 1,237 16 65 2 4.5E-21
TAF1 4,126 297 295 53 82 2 3.5E-05 BCL3 3,924 265 263 19 54 1 3.8E-12 SIN3A 2,701 320 318 4 34 1 6.8E-21STAT2_6h 2,174 341 332 60 88 2 1.3E-04 TAF1 4,126 551 544 40 86 2 1.3E-11 JUND 945 256 256 3 31 1 8.8E-21
TAF7 4,536 170 167 30 50 1 1.7E-04 STAT2_6h 2,174 477 474 35 78 2 1.6E-11 SIRT6 1,794 1,230 1,227 16 64 2 1.3E-20SRF 2,005 198 198 36 57 1 1.9E-04 ZBTB33 4,530 368 368 27 65 2 3.1E-11 GTF2F1 885 90 90 1 20 1 2.7E-19
NR4A1 5,514 636 615 111 145 4 5.3E-04 STAT1_30m 1,057 203 202 15 43 1 1.7E-10 SRF 2,005 666 666 9 39 1 9.9E-15BCL3 3,924 307 297 54 78 2 4.7E-04 GATA2 9,025 1,039 1,036 76 126 3 2.2E-08 TAF1 4,126 580 573 7 36 1 1.3E-14
RAD21 17,401 898 883 160 195 5 2.1E-03 SRF 2,005 222 221 16 41 1 3.0E-08 BCL3 3,924 493 492 6 32 1 1.4E-13PU1 25,479 1,093 1,068 193 230 6 3.3E-03 STAT1_6h 1,245 262 261 19 45 1 6.7E-08 INI1 8,061 3,796 3,762 48 106 3 1.6E-13
SMC3 23,337 1,835 1,796 325 357 9 4.1E-02 MAFK 17,914 890 888 65 109 3 1.1E-07 STAT1_30m 1,057 605 602 8 33 1 6.2E-12GATA1 3,182 225 224 41 55 1 1.4E-02 RPC155 2,075 480 467 34 65 2 6.1E-07 ZNF263 8,128 1,324 1,322 17 48 2 2.8E-10
STAT1_30m 1,057 170 169 31 43 1 1.6E-02 BCLAF 6,616 618 592 43 75 2 3.3E-06 SMC3 23,337 2,531 2,531 32 73 2 3.6E-10BCLAF 6,616 259 247 45 59 2 2.0E-02 CTCFL 8,572 971 970 71 108 3 1.5E-05 THAP1 1,606 206 204 3 17 1 1.7E-09
MAFK 17,914 676 669 121 141 4 4.6E-02 RAD21 17,401 1,424 1,424 104 66 2 4.3E-05 CTCFL 8,572 1,224 1,216 16 43 1 5.0E-09NRSF 5,715 442 440 80 63 2 3.9E-02 GATA1 3,182 328 328 24 42 1 3.9E-04 STAT1_6h 1,245 519 517 7 26 1 6.0E-09
STAT1_6h 1,245 211 208 38 49 1 4.6E-02 TAF7 4,536 335 333 24 41 1 9.8E-04 NELFE 1,136 46 46 1 9 0 6.4E-09GATA2 9,025 633 621 112 173 4 2.5E-01 BRF1 317 173 163 12 22 1 5.8E-03 SETDB1 8,379 669 669 9 29 1 2.2E-08CTCFL 8,572 709 704 127 139 4 2.5E-01 SIRT6 1,794 246 246 18 30 1 6.3E-03 SPT5 1,839 197 197 3 15 0 5.0E-08SIRT6 1,794 141 141 26 33 1 1.0E-01 NRSF 5,715 286 286 21 32 1 1.6E-02 RPC155 2,075 623 622 8 25 1 7.9E-07BRF1 317 46 44 8 13 0 7.4E-02 BDP1 520 251 244 18 28 1 1.8E-02 ZBTB33 4,530 678 674 9 25 1 3.3E-06
MEF2A 10,209 261 255 46 41 1 4.6E-01 SMC3 23,337 2,689 2,677 195 166 4 2.4E-02 RAD21 17,401 1,855 1,854 24 49 2 3.4E-06FOSL 11,393 328 322 58 62 2 5.6E-01 POL3 563 219 196 14 23 1 2.6E-02 NRSF 5,715 691 691 9 25 1 5.0E-06POL3 563 65 61 11 15 0 1.8E-01 BRF2 67 12 12 1 3 0 5.2E-02 TR4 612 44 44 1 3 0 1.9E-02KAP1 12,314 147 146 26 22 1 3.9E-01 HDAC2 8,831 498 493 36 29 1 2.6E-01 BDP1 520 84 84 1 4 0 2.3E-02
HDAC2 8,831 213 206 37 39 1 7.2E-01 FOSL 11,393 571 570 42 37 1 5.2E-01 POL3 563 46 46 1 2 0 1.2E-01BDP1 520 89 88 16 18 0 5.8E-01 P300 2,969 126 126 9 10 0 7.3E-01 ZNF274 794 12 12 0 1 0 1.4E-01P300 2,969 75 75 14 11 0 5.5E-01 MEF2A 10,209 643 639 47 45 1 8.8E-01 BRF1 317 26 26 0 1 0 2.8E-01
BRF2 67 7 7 1 2 0 6.2E-01 KAP1 12,314 48 48 4 3 0 1.0E+00 KAP1 12,314 437 437 6 7 0 5.2E-01XRCC4 201 7 7 1 1 0 1.0E+00 ZNF274 794 3 3 0 0 0 1.0E+00 BRF2 67 4 4 0 0 0 1.0E+00ZNF274 794 9 4 1 0 0 1.0E+00 XRCC4 201 5 5 0 0 0 1.0E+00 XRCC4 201 3 3 0 0 0 1.0E+00
n = 21,641 n= 51,916 n= 249,997n = 3914 n- 3788 n= 3193
Promoters (all) Enhancer (all)
40/50 TFs show correlations,P value E-40