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Unit 4 the Respiratory System

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    Science Interactive LTD

    Science Interactive LTD. PO BOX 50764 LONDON NW6 9AT email: [email protected] web: www:science-interactive.co.uk

    Science Interactive LTD Copyright 2005

    Science base multimedia CD-ROM forPC is a collection of38 units or tools totalling over1150

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    Unit 38: Cells, Tissue, Organs and Organs systems

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    Unit 4: The Respiratory System

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    z Unit 4

    z The Respiratory System

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    Unit 4: The Respiratory SystemUnit 4: The Respiratory System Science Interactive LTD Copyright 2005

    Understand: Keywords:

    1. The role of the respiratory system and its keyorgans.

    2. The breathing cycle and the role of the eachtissue during breathing and gaseous exchange.

    3. The exchange of oxygen and carbon dioxidebetween blood and the alveoli tissue.

    4. The similarities and differences betweenexpired and inspired air.

    5. How haemoglobin in the red blood celltransports oxygen from the alveoli tissue torespiring cells in the body.

    6. How smoking affects lung function, whilstincreasing the risk of developing lung cancer oremphysema.

    7. How asthma affects normal lung function.

    8. The role of oxygen in cellular respiration.

    9. The differences between anaerobic and aerobicrespiration.

    10. How the body recovers from oxygen debt.

    11. How to maintain bodily fitness for life and therole of the circulatory, respiratory, nervous anddigestive system during exercise.

    Lungs, Diaphragm, Ribs, Alveoli, Intercostalmuscles, Oxygen, Carbon dioxide, Red bloodcells, Haemoglobin, Heart, Inhalation,Exhalation, Respiration, Anaerobic, Aerobic,Fitness, Bronchitis, Emphysema, Cancer &Exercise.

    web: www.science-interactive.co.uk email: [email protected] Interactive LTD PO BOX 50764 LONDON NW6 9AT

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    The respiratory systemThe respiratory system oneone

    The respiratory system, a collection of cells, t________ and organs works constantly to

    provide the many billions of cells in the human body with oxygen. The lungs allow

    gaseous e__________ taking oxygen from the atmosphere into the blood and excretingcarbon dioxide from the blood to the atmosphere. A healthy lung consists of many

    millions of alveoli giving it a huge surface area to help the exchange of these gases. These

    are highly specialised tissues for exchanging gases. How do villi in the small intestine

    make use of a large surface area for absorbing nutrients ?

    The respiratory system: Word bank: tissues exchange

    The lung tissue is

    supplied with air by a

    vast network of tubescalled bronchioles. Your

    windpipe is kept open by

    rings of cartilage.

    Airways

    Your lungs are in constant

    contact with the outside.

    They are also verysensitive to pollutants.

    Over 100,000 deaths a year

    are because of lung cancer.

    Smoking

    Your lungs are

    constantly inhaling and

    exhaling air. Left X rayin this picture shows

    the lungs fully

    expanded.

    Your chest is home to

    your lungs. They are

    both surrounded andprotected by your rib

    cage, a collection of

    bones and muscles.

    Notes

    Diagram

    Thorax Lung volume

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    The respiratory systemThe respiratory system twotwo

    Diaphragm

    Intercostal

    muscles

    Ribs

    Lungs

    Bronchiole

    Bronchus

    Windpipe

    Tissue

    Moves the ribs.

    Changes the volume of the

    thorax.

    Protects and moves the thorax.

    Allow gas exchange.

    Transports air to alveoli tissue.

    Transports air to bronchioles.

    Transports air to alveoli tissue.

    Function

    Alveoli

    Capillaries

    Bronchioles

    Alveolus

    Alveoli

    The lungs are the key organs in the r__________ system. They are located inside your chest or

    thorax. The lungs delicate tissues are protected by your ribs. Below your lungs is the

    diaphragm, which aids breathing and separates your lungs from your a__________. Theaverage lung capacity of an adult male is around 5.5 litres. Lance Armstrong, the cyclist, who

    recently won seven Tour de Frances has a lung capacity in excess of 7 litres. Females have a

    smaller lung capacity because of their smaller body mass.

    The respiratory system:Word bank: respiratory abdomen

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    Breathing cycleBreathing cycle oneone

    Your lungs are constantly working to exchange oxygen for carbon dioxide between the alveoli

    tissue and the pulmonary capillary network. At rest, your lungs e_______ and c_______ about

    fifteen times every minute. The breathing rate can increase depending on the oxygen demandfor your entire body. Your intercostal muscles, ribcage and diaphragm work together to help

    your lungs inhale and exhale during gaseous exchange. What happens to you breathing rate

    during periods of exercise and sleep ?

    Breathing cycle: Word bank: expand contract

    Notes

    Diagram

    Breathing in:

    1: Your intercostal muscles contract raising your

    ribs upwards and outward.

    2: Your diaphragm moves downwards.

    3: The volume of the thorax increases and thepressure decreases.

    4: Air rich in oxygen rushes into the lungs.

    Breathing in (Inhalation)

    Breathing out:

    1:Your intercostal muscles relax, lowering your

    ribs downwards and inwards.

    2: Your diaphragm moves upwards.

    3: The volume of the thorax decreases and thepressure increases.

    4:Air rich in carbon dioxide rushes out of the lungs.

    Breathing out (Exhalation)

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    Breathing cycleBreathing cycle twotwoAs you complete a full breathing cycle (inhalation & exhalation) you are not only taking in

    oxygen from the atmosphere, you are also getting rid of waste carbon dioxide. Oxygen moves

    from an area of high concentration (in the atmosphere) to an area of low concentration (in theblood) by diffusion. In your a_______, you exchange what you need for what you dont need.

    The air you breathe out is rich in carbon dioxide, moving from an area of high concentration (in

    the blood) to an area of low concentration (in the atmosphere), also by diffusion.

    Breathing cycle:

    py g

    Word bank: alveoli

    HighLowHumidity

    37oC20oCTemperature

    79%79%Nitrogen

    4%0.04%Carbon dioxide16%20%

    Oxygen

    Exhaled airInhaled air

    Notes

    Diagram

    In this model of a lung, the rubber diaphragm

    moves downwards increasing the volume of the

    bell jar and decreasing the pressure. Air from

    outside rushes in. During exhalation, the

    diaphragm moves upwards, reducing the volume

    and increasing the pressure. Air rushes out.

    Model of the human lung

    The table above shows the composition of

    gases, humidity and temperature of

    inhaled and exhaled air. Look at the

    information and explain the changes in

    composition of gases, humidity and

    temperature of inhaled and exhaled air ?

    Composition of inhaled and exhaled air

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    Lung volumeLung volumeDuring normal breathing, our l_______ take in about half a litre of air during inhalation and

    exhalation. During heavy exercise, we can take in about 3 litres of air per cycle. The maximum

    volume of air that we can take in is about 5 litres. We can measure our total lung volume orvital capacity andpeak flow of airwhilst breathing out.If you compare your vital capacity and

    peak flow with professional athletes, how might they differ ?

    Lung volume: Word bank: lungs

    Lung volumes:

    (a) Tidal volume (breathing at rest)

    (b) Inspiratory reserve volume

    (c) Expiratory reserve volume

    (d) Vital lung capacity (Inhalation + Exhalation)(e) Residual volume (always present in lung)

    (f) Total lung capacity

    Lung volumes

    Notes

    Diagram

    Your peak flow rate can be measured

    using a device as pictured above. It

    tells us the rate at which air is forced

    out of your lungs through your wind

    pipe. Smokers, the elderly and

    asthmatics can all have a reduced

    peak flow rate. Why does smoking

    affect peak air flow ?

    Measuring peak volume

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    The alveoliThe alveoliWhen inhaled air, rich in o__________ reaches the alveoli tissue, oxygen has to transfer to

    the blood, so it can be transported through the vascular system to the entire body. Oxygen

    diffuses across the thin alveoli tissue into the b______ where it binds to the red bloodcells. The alveoli tissue is highly specialised to help diffusion. They are extremely thin

    (one cell thick), are kept moist and have a large surface area. If you were able to spread

    out the lung it would cover a whole tennis court !

    The alveoli tissue:

    O2

    O2

    O2

    O2

    O2

    O2

    Word bank: oxygen blood

    Oxygen in the air dissolves in the fluid

    that coats the alveoli tissue. It then

    diffuses across to the blood so it can be

    transported to respiring cells in thehuman body. Carbon dioxide diffuses in

    the opposite direction and is excreted in

    expired air.

    Alveoli tissue

    The alveolus has a very thin

    wall and large surface area

    which is kept moist. These three

    features help the diffusion ofoxygen and carbon dioxide

    across its wall. The alveolus

    also has a rich blood supply.

    Single alveoli

    The lung tissue is supplied

    with air by a vast network

    of tubes called bronchioles.

    At the end of eachbronchiole are many

    thousands of alveoli which

    allow gaseous exchange.

    Notes

    Diagram

    Bronchiole

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    Oxygen transport by blood haemoglobinOxygen transport by blood haemoglobinRed blood cells contain the protein haemoglobin, which is responsible for binding oxygen

    at the l______ tissue (alveoli) and delivering it to every r____________ tissue or cell via a

    huge capillary network. This network can be up to 50,000 km in the human body.Haemoglobin also contains the mineral i_____, to help oxygen transport. Why is iron

    important in the diet and why do females require greater quantities of this mineral ?

    Oxygen transport:

    CO2

    O2

    O2

    CO2

    O2

    O2O2

    CO2

    O2

    O2

    Haemoglobin

    Oxyhaemoglobin

    Haemoglobin is a protein found

    in the red blood cell. It contains

    Iron (Fe2+) and is able to bind

    oxygen at several sites. Namethree foods rich in the mineral

    iron ?

    Haemoglobin

    Oxygen diffuses across the thin

    capillaries walls to the respiring

    cells. It travels from an area of

    high concentration inside thecapillary to an area of low

    concentration inside the cells.

    In the tissues

    Air contains 21% oxygen which

    is taken to the alveoli tissue by

    the bronchioles. Oxygen

    dissolves across the thin alveolisurface and binds to red blood

    cells.

    Notes

    Diagram

    At the alveoli

    Word bank: lung respiring iron

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    G h i th llG h i th ll

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    Gaseous exchange in the cellsGaseous exchange in the cellsBlood capillaries have a very small diameter allowing only one red blood cell through at a

    time. Blood flows very slowly through your c__________. The capillaries are extremely

    thin walled which allows oxygen and plasma containing nutrients to diffuse to the cells.Also waste products like u_____ and carbon dioxide can pass from the cells back to the

    capillary. Why do red blood cells not pass through the capillary walls ?

    Understanding your capillaries:

    Oxygen Glucose Amino acids Water

    CarbonUrea Wastesdioxide

    Netpressure

    Cells

    Word bank: capillaries urea

    Oxygen and nutrients including glucose diffuse from blood across

    the capillary wall to the cells. These are used during cellularrespiration. Waste products including carbon dioxide and urea are

    transported back in the plasma to the lungs and the kidneys.

    An electron micrograph of

    a single capillary. Noticethe narrow diameter

    allowing only one blood

    cell through.

    Notes

    Diagram

    Capillaries Capillary exchange

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    Blood circulationBlood circulationThe circulation of blood through the heart, lungs and other major organs keeps the human

    body supplied with the o______ and nutrients that it requires for cellular respiration,

    growth and repair. This transport system also carries the white blood cells, platelets andantibodies around the body defending us against microbial infection. What lifestyle

    factors can prematurely age your cardiovascular system ?

    Circulation in the body: Word bank: oxygen

    O2 O2O2O2

    CO2CO2

    Tissue

    Red Blood Cell Red Blood Cell

    Oxygen is exchanged for carbon dioxide at the tissue

    surface. Oxygen diffuses across the capillary wall

    into the cells or tissue. Oxygen is combined with

    glucose during cellular respiration. Waste productsincluding carbon dioxide and urea are transported in

    the plasma to the lungs and the kidneys.

    Capillary exchange in detail

    G h i illG h i illScience Interactive LTD Copyright 2005

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    Oxygen rich

    water

    Gills

    Gas exchange using gillsGas exchange using gillsFish do not have lungs. They are equipped with gills to obtain oxygen for cellular respiration

    from water. Like lungs, fish gills are highly specialised to allow the d_________ of oxygen

    from water into the blood. They have a large s________ area, are very thin and have numerouscapillaries to transport oxygen away from the gill to the rest of the body. Describe how the

    shape of gills and alveoli in lungs have common features to help gaseous exchange ?

    Gas exchange in fish: Word bank: diffusion surface

    Water rich in oxygen flows over the delicate

    membranes. The oxygen diffuses into the blood

    supply and travels around the body. Carbondioxide, the waste product of respiration diffuses

    from the body, into the water.

    Gas exchange in fish gills

    Notes

    Diagram

    Fish have evolved gills to exchange

    oxygen and carbon dioxide between water

    and the blood supply. The gills have a richblood supply and have a very large surface

    area.

    Gas exchange in fish

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    P t ti th lProtecting the lungs

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    Protecting the lungsProtecting the lungs

    Hair cells and mucus

    Bacteria

    Hair

    cells

    The ciliated hair cells

    trap dust, dirt and

    bacteria preventing them

    entering the delicate lung

    tissue. Smoking damages

    these specialised cells.

    Ciliated epithelia cells

    Thousands of hair like protrusions trap dust and

    bacteria. This is then covered in a sticky mucus

    which is secreted by the goblet cells. The hairs

    beat the mucus and bacteria to the back of the

    throat where it is swallowed. Bacteria are then

    destroyed by the acid in the stomach.

    Trapping dirt and microbes in the trachea

    Inhaled air is warmed and

    made moist by the nasal

    cavity which is richly

    supplied by warm blood

    through thousands of

    capillaries.

    Notes

    Diagram

    Warm and moist air

    The lungs are vulnerable to cold air or infection, caused by bacteria or viruses. Cold, dry

    air is warmed and moistened by the lining found in your n______ and trachea. Bacteria

    and viruses are trapped by ciliated epithelial cells that line the trachea. Furthermore, thesecells also produce m_______ which trap any airborne microbes, which are then moved by

    the cilia (hairs) to the back of your throat. Here they are swallowed and destroyed by

    stomach acid.How does smoking damage these cilia hairs ?

    Protecting the lungs: Word bank: nose mucus

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    D i lDamaging o r l ngs

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    Damaging your lungsDamaging your lungsIn addition to smoking, your lungs can be damaged by your life style, your place of work

    or even a traffic jam. Our lungs take in overfifty litres of air every minute of the day. The

    quality of the a____ we breathe at work, where we live and play affects how our lungsperform over our lives. Remember, our lungs are the most sensitive organs we have and

    can be quickly damaged by our lifestyles and our own e____________. How might the

    pollutants from cars and lorries affect our lungs ?

    Damaging your lungs:Word bank: air environment

    Traffic pollution can

    affect the quality of the

    air we breathe. In our

    cities, traffic pollutioncan increase the number

    of deaths from

    respiratory failure.

    Air pollution

    Many work places can

    expose our lungs to dust

    and other airborne

    pollutants. We canprotect ourselves by

    wearing a face mask,

    which filters out dust.

    Work

    Notes

    Diagram

    Risk

    Smoking in the U.K

    kills over 100,000

    adults per year. Despite

    these figures, thegovernment has yet to

    ban smoking from

    public places.

    Smoking

    Our lifestyles can also

    damage our lungs.

    Smoking and living near

    busy car jammed roadscan damage our delicate

    lungs for the rest of our

    lives.

    Lifestyle

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    Smoking and its effects on the human bodySmoking and its effects on the human bodyNicotine, the active c__________ in cigarette smoke is highly a__________. Nicotine

    itself, has an effect on the heart and blood pressure like other stimulants but, it is the t____

    and carcinogenic chemicals in cigarette smoke that leads to an increased risk of developinglung, throat and mouth cancer. Smoking over two decades can also lead to the

    development of emphysema. This disease causes the breakdown of the alveoli tissue.

    Make a list of the reasons why people start to smoke when they are young ?

    Smoking and its effects:

    Lung cancer kills about 100,000

    people in the UK every year with the

    majority of incidents caused by

    smoking or passive smoking at workand home. The number of deaths in

    females is rising...why ?

    Effect on major organs

    Notes

    Diagram

    The average UK smoker

    consumes 20 cigarettes per

    day until death from heart

    failure or lung cancer. Whatis the addictive agent in

    cigarette smoke ?

    Cigarettes (smoke & tar)

    Increased heart rate and

    blood pressure may lead to

    heart disease. This is a major

    cause of death in smokers.Pictured is a heart valve

    replacement in a smoker.

    Other effects

    Word bank: chemical addictive tar

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    .

    Smoking as a cause of lung cancerSmoking as a cause of lung cancerSmoking was first linked as a direct cause of lung cancer by the scientist John Doull. He

    studied the main causes of death in many thousands of smokers and non smokers. His research

    linked s_________ with an increased risk of dying from lung cancer. Smoke irritates the lungcausing new cells to grow. Dividing lung cells expose their genes orDNA to the cancer-causing

    chemicals in cigarette smoke and t_____. A change in the lung cell DNA results in lung

    c________ in the future.

    Lung cancer and smoking: Word bank: smoking tar cancer

    Drugs, chewing gum

    and inhalers all supply

    the addictive drug

    nicotine to help

    smokers give up their

    habit. Why is will

    power also important

    when quitting ?

    Giving up

    Key (Death rates in the US)70/100,000

    50/100,000

    35/100,000

    20/100,000From the graph more people smoke in

    coastal areas or in large cities.

    Smoking is still seen as a social habit.

    Cancer Deaths in America

    Notes

    Diagram

    An X-ray of a cancerous lung tissue (right)

    Six tumours are growing and increasing in

    size in both the right and left lung. Untreated

    this patient will die form the presence of all

    these tumours. The right picture shows the

    lung of a dead 56 year old male smoker.

    Notice how the tissue has changed because of

    the build up of tar deposits.

    Cancer x-ray Lung cancer

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    Other effects of smoking on the human bodyOther effects of smoking on the human bodyIn addition to lung cancer, smoking over a long period can increase the risk of developing

    emphysema and chronic bronchitis. Again, many of the 300 chemicals that cigarette tar contains

    causes these respiratory diseases, particularly in the heavy smoker. Emphysema is a fatal lungcondition involving the breakdown of the a________ tissue, causing many years of suffering.

    Coal miners and others whose occupations have exposed them to dust and pollutants can also

    suffer from these diseases.

    Emphysema and bronchitis: Word bank: alveoli

    See how the lung alveoli

    have been destroyed by

    the inner walls breaking

    down. Less oxygen is

    able to diffuse across the

    lung into the blood

    stream.

    Emphysema

    The alveolus has a very

    thin wall, a large surface

    area which is kept moist

    and a good blood supply.

    These four features help

    the diffusion of O2 and

    CO2 across its wall.

    Normal alveoli

    Notes

    Diagram

    Normal bronchioles

    have a large diameter

    which transports

    inhaled and exhaled air

    to and from the alveoli

    tissue out through the

    windpipe.

    Normal bronchioles

    Bronchitis can be fatal

    in the very old and in

    smokers. Excessive

    mucus can damage the

    delicate lung tissue

    causing scaring and lead

    to infection.

    Bronchitis

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    Aerobic cellular respirationAerobic cellular respiration

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    Aerobic cellular respirationAerobic cellular respirationAerobic cellular respiration is the release of energy from the breakdown of glucose to water

    and carbon dioxide. Oxygen from the atmosphere is required to b___________ glucose

    forming carbon dioxide, water and energy. Respiration occurs in every cell, inside themitochondria. In animals, 90% of the energy available from ingested food is used for every day

    activities like muscle contraction, transporting chemicals, absorbing food, building new cells

    and maintaining a constant body temperature. Why do vegetarians have less impact on the

    environment ?

    Energy use of ingested food: Word bank: breakdown

    1

    1

    2

    2

    33

    Faeces

    Growth

    Respiration

    Faeces:Energy contained in

    the faeces and undigested

    food of the animal.

    Growth: Energy containedin the tissues of the animal

    (available for the next level.)

    Respiration: Energy used in

    cellular respiration and for

    body heat.

    25,000 kJ

    20,000 kJ

    5,000 kJ

    Nutrients

    50,000kJ

    Nutrients

    50,000kJ

    Half the energy (25,00 kJ) in

    ingested food passes

    undigested through the

    horse's body as waste or

    faeces.

    The daily nutrient requirement for a horse is around 50,000

    kJ with only 5,000 kJ of nutrients ending up as part of the

    horses body. 20,000 kJ is used for muscle activity, transport,

    absorbing and digesting food and maintaining a constant

    body temperature.

    Notes

    Diagram

    Energy use in animals Process

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    Aerobic respiration in the cellsAerobic respiration in the cells

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    Aerobic respiration in the cellsAerobic respiration in the cellsIf you view animals cells under a microscope, you can see tiny dots in the cytoplasm. These are

    mitochondria. Cellular respiration occurs in the mitochondria releasing energy from the

    breakdown of g________ using oxygen. All living things give out carbon dioxide, a wasteproduct of cellular respiration. Muscle cells contain many mitochondria because they require lots

    of energy. Even plants and simple bacteria contain mitochondria for respiration.

    Respiration and mitochondria: Word bank: glucose

    C6H

    12O

    6

    6O2

    6CO2

    6H2O

    Cells

    Mitochondria Energy

    Diagram

    Mitochondria

    To respire glucose with oxygen providing cell

    energy. All living cells have these mitochondria.

    Cellular respiration equation:

    C6H12O6 + 6O2 6H2O + 6CO2Glucose Oxygen Water Carbon dioxide

    Notes

    Body temp (o

    C)Nerve messages Building cellsDigestion

    Diagram

    Use Muscles Transport

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    Respiration and combustionRespiration and combustionRespiration inside human cells using glucose and oxygen is like the combustion of fossil

    fuels like p______, which is rich in alkanes like octane. When we combust these fuels with

    oxygen, energy in the form of h____ and motion is released. New substances are alsoproduced including carbon dioxide and water.

    Equation:

    2C8H18 + 25O2 CO2 + 18H2O

    Octane Oxygen Carbon dioxide Water

    Combustion: Word bank: petrol heat

    The waste products are

    carbon dioxide and water.

    However, carbon and

    carbon monoxide are alsoreleased. Compare

    cellular respiration to

    combustion in an engine ?

    Products

    The engine is designed to

    convert the chemical

    engine contained in

    octane to kinetic energy.It is highly inefficient

    releasing only 13% of

    octanes energy.

    Engine

    Notes

    Diagram

    In a modern car,

    combustion of fuels

    like petrol provides the

    energy to moveforward. Like cellular

    respiration waste gases

    are produced.

    Car engine

    In the engine, huge

    amounts of oxygen are

    combined with octane.

    This releases lots ofuseful forms of energy

    contained in carbon

    rich petrol.

    Octane & Oxygen

    Anaerobic respirationAnaerobic respiration

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    Anaerobic respirationAnaerobic respirationDuring exercise your muscles use oxygen and glucose during cellular respiration. This provides

    the energy all m_______ cells need to be able to contract and move your body. During

    vigorous exercise your cardiovascular system cannot supply enough o________ to yourmuscles. When the demand for oxygen outstrips the supply, your muscle respire glucose

    without oxygen, producing lactic acid. This is known as anaerobic respiration. When lactic acid

    builds up in the muscles what does it cause ?

    Anaerobic respiration:

    C6H

    12O

    6

    6O2 Carbon

    Lactic acid

    dioxide

    Sugar

    Word bank: muscle oxygen

    The build up of lactic acid can cause

    exhaustion in trained athletes. When

    you sprint over 100 metres the burning

    sensation you can feel in the legs isbecause of lactic acid build up in your

    muscles.

    Lactic acid and exhaustion

    Notes

    Diagram

    The skeletal muscles in your legs and arms are able to respire

    glucose without oxygen forming lactic acid. Although less

    energy is produced during anaerobic respiration, your muscle

    can continue to respire without oxygen for several minutes.Athletes train so they can endure the pain associated with lactic

    acid build up.

    Anaerobic respiration in muscle cells

    Oxygen debt during anaerobic respirationOxygen debt during anaerobic respirationScience Interactive LTD Copyright 2005

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    Oxygen debt during anaerobic respirationyg g pWhen muscles are working hard, they begin to respire glucose without oxygen. This is called

    anaerobic respiration. Lactic acid produced during anaerobic respiration builds up and slowly

    poisons your muscles. Your body cant supply sufficient oxygen to your muscles. This is called

    oxygen debt. When you stop vigorous exercise, your heart and lungs continue to supply extra oxygen

    to allow the muscle to breakdown l____ acid. This repays the oxygen debt.

    Oxygen debt:

    A

    B C

    Word bank: lactic

    Time (Minutes)

    Oxygens

    upply(litres) O

    xygendem

    and(litres)

    0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

    Oxygen supply

    Oxygen demand

    Oxygen debt

    0

    0.25

    0.5

    0.75

    1.0

    1.25

    1.5

    1.75

    2.0

    2.25

    2.5

    0.25

    0.5

    0.75

    1.0

    1.25

    1.5

    1.75

    2.0

    2.25

    2.5

    0

    a

    b

    c

    C6H12O6

    Carbondioxide

    Sugaracid

    6O2

    Lactic

    During anaerobic respiration, less

    energy is produced respiring glucose

    without oxygen. Lactic acid builds upand begins to damage your muscles,

    giving you the sensation of the

    burn.

    Lactic acid production in muscle

    Notes

    Diagram

    During rest (a) the supply of oxygen to the muscles meets demand.

    During hard vigorous exercise (b), demand increases above supply

    and the muscle have to continue respiring glucose without oxygen.Anaerobic respiration leads to the oxygen debt and formation of

    lactic acid. This oxygen debt is repaid when exercise stops (c) by

    the lungs continuing to oversupply the muscles with the lungs.

    Oxygen debt in muscles

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    Complete fitnessComplete fitness

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    ppAthletes require their key organ systems to work together so that they can exercise and

    play their sport. Fitness is a measure of how well you body w_____ and exercises.

    Athletes require total fitness so that they can win and excel at their s______. Thecardiovascular, respiratory and skeletal-muscle system all work together to supply the

    oxygen and nutrients to your muscles. How would you devise a training programme to

    increase your overall fitness ?

    Essential organ systems: Word bank: works sport

    The skeletal-muscle

    system works to move

    the body during sport.

    A sprinter requires the

    fastest contractingmuscles during a 100 m

    race.

    Muscle

    Your respiratory system

    is constantly working to

    exchange oxygen for

    carbon dioxide between

    the alveoli and thepulmonary capillaries in

    the lung.

    Respiratory

    Notes

    Diagram

    Professional athletes

    like runners and

    footballers work hard

    to be fit for their sport,

    but ideas of fitnessvary according to their

    sport.

    Athlete

    The cardiovascular system

    is the human bodys

    transport system. It moves

    oxygen, carbon dioxide,

    nutrients, hormones, andimmune cells around a

    network of tubes.

    Cardiovascular

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    Maintaining fitnessMaintaining fitness

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    Maintaining fitnessMaintaining fitnessAthletes work hard to achieve total fitness, but what does being fit mean ? If you are fit,

    you will have a low resting heart rate which recovers quickly after e_________. Your

    lungs efficiently exchange oxygen and carbon dioxide at the alveoli tissue and yourskeletal m________ system moves you quickly, without tiring during a race or a game.

    Exercising (running, weights & gym work) helps us to achieve fitness and improve our

    ability to compete and win.

    Fitness and the five S Word bank: exercise muscle

    Suppleness SpeedSkill

    Diagram

    Strength Stamina

    Notes The five s strength, stamina, skill, suppleness and speed are all improved by

    repetitive training and exercise. Regular exercise also helps prevent people becoming

    overweight and developing heart disease and diabetes. Nearly 25% of all adults are

    now considered obese with almost 50% of all pupils of secondary school age not

    taking enough exercise.

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    Fermenting grape and grainFermenting grape and grain

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    Fermenting grape and grainFermenting grape and grainMany microbes including yeast can respire successfully without oxygen. Yeast can respire

    glucose successfully with or without oxygen. When yeast respires glucose without oxygen, it is

    called fermentation. Fermentation of s_______ from grape or other crops produces alcohol.Wine has been made from grapes using yeast for many centuries. The Romans developed

    vineyards to supply Rome with w______ from about 400 B.C. onwards. Using the Internet,

    research into how they make beer from barley, yeast and hops ?

    Anaerobic respiration producing alcohol: Word bank: sugar wine

    The finished product is

    taxed by the government

    raising huge tax

    revenues. Duty on

    alcohol raises more than

    8 billion per year.

    Final product

    Alcohol is produced in

    huge quantities to supply

    all drinkers. Weekly,

    females are allowed 14

    units, compared with 21

    units for males.

    Fermentation

    Notes

    Diagram

    The sugar in grapes,

    rice, potato, oats and

    barley are used to

    manufacture many

    different types of

    alcohol including wine.

    Sugar in grapes

    Yeast is a naturally

    occurring bacteria that

    during fermentation

    produces alcohol and

    carbon dioxide as waste

    products.

    Yeast microbes

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    Industrial fermentation using yeastIndustrial fermentation using yeast

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    g yg yYeast is a very important microbe that supports alcohol manufacture, a multibillion pound

    industry. Sugar from wheat or grapes is converted to alcohol (beer or wine) in the absence of

    oxygen by yeast microbes. During f___________, alcohol is produced as a waste product byyeast. Brewing wine or beer are good examples of using biotechnology. Many other useful

    chemicals can now be made using all types of m________ using fermentation technology.

    Research into how synthetic insulin for diabetics is manufactured using biotechnology ?

    Alcohol fermentation: Word bank: fermentation microbes

    C6H12O6

    Carbon

    Alcohol

    dioxide

    Sugar

    Yeast

    6O2

    After fermentation, the alcohol is

    separated from the dead yeast

    cells and allowed to mature over

    time. Distilling alcohol increases

    its content in spirits like vodka.

    Yeast is used in the manufacture of wine, beer and

    spirits. Sugar contained in grapes or grain is fermented

    by yeast producing alcohol. The yeast cells multiply

    rapidly in the sugar until they run out of the food source

    or high concentrations of alcohol kill them.

    Notes

    Diagram

    Fermentation using yeast Final products

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    Extension questions and homework

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    q

    Amino acids

    Fatty acids

    Glucose

    glycerol

    O2

    O2

    O2

    O2

    O2

    O2

    O2 richwater

    Gills

    1: Define the following terms: Inhalation, Exhalation, Respiration, Anaerobic, Aerobic, Gas exchange & Fitness.

    2: Look at the diagram of the three types of surfaces which exchange substances like oxygen or nutrients by

    diffusion. Complete the table.

    3: Answer the following questions:a) How does oxygen in the atmosphere move into your bloodstream.

    b) How is carbon dioxide removed from your respiring cells as a waste product by the lungs.

    c) The common features of surfaces that allow gas exchange. Name three of them.

    d) The key elements of the breathing cycle (inhalation and exhalation)

    e) How are gills in fish similar to lungs found in all mammals.

    f) Describe the journey of an oxygen molecule from the air sac to muscle tissue in your lower leg.

    Yes

    Large surface area (Y/N)

    Gills

    YesSmall intestine (villi)

    YesAlveoli

    Moist (Y/N)Rich blood supply (Y/N)Tissue

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    4: Look at the information in the table below. It shows the results of an investigation designed to investigate how

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    breathing changes during exercise:

    a) How many breaths did the volunteer take during (i) Rest (ii) When doing 25 press ups per minute.

    b) Calculate the amount of oxygen (cm3) breathed in at (i) Rest (ii) When doing 50 press ups per minute.

    c) What would the persons breathing be like shortly after exercise was finished.

    5: Answer the following questions:

    a) Describe the differences between aerobic and anaerobic respiration.

    b) Describe the role of the mitochondria in cells. Which types of tissue contain the most mitochondria and why

    c) Explain why the build up of lactic acid in your leg muscle begins to slow your speed during a sprint race.

    d) Explain why the heart can never respire anaerobically.

    e) Explain how red blood cells are adapted to carry oxygen. How does haemoglobin transport oxygen.

    6: Complete the following:

    During a 200 metre race, the lungs supply ___________ to the respiring muscles. Waste carbon dioxide is taken via

    the blood stream and excreted by the ________. All athletes begin to become tired, because of the build up of

    _______________ in the muscles. This is called _______________ respiration.

    351250Press ups (40 min-1)

    26800Press ups (25 min-1)

    19

    Number of inhalations per minute taken

    600Resting

    Volume of each inhalation (cm3)Activity

    Internet:Go to google.co.uk and find about how athletes use the illegal drug EPO which stimulates the production of red

    blood cells. How might this give them an advantage over other athletes. Whys is this dangerous for the athlete.