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Unit 4 – Lecture 7
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Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Dec 31, 2015

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Page 1: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Unit 4 – Lecture 7

Page 2: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Review Mendellian / Single-Gene Inheritance

two alleles per gene = 1 dominant, 1 recessive

ex: R = red, r = blueRR = redRr = redrr = blue

COLOR THE IMAGES ON YOUR LECTURE NOTES

Page 3: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Discuss

What does it mean to be “incomplete” ?[don’t say – to not be complete…think about

this]

Page 4: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Incomplete DominanceIncomplete Dominance

two dominant alleles present BLEND of alleles is expressed when

combineduses same letter with “prime” or

another letter as exponentcan have a recessive allele still – which is

hidden by BOTH of the dominant alleles if present.

A 1

Page 5: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Incomplete Dominance – cont’dIncomplete Dominance

ex: R = red, R1 = blueRR = redRR1 = PURPLER1R1 = blue

COLOR THE IMAGES ON YOUR LECTURE NOTES

Page 6: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

CodominanceCodominance

two dominant alleles presentBOTH alleles are expressed when combinedoffspring show both phenotypes at same timeuses same letter with “prime” or

another letter as exponentcan have a recessive allele still – which is

hidden by BOTH of the dominant alleles if present.

Page 7: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Codominance – cont’d Codominance

ex: R = red, R1 = blueRR = redRR1 = red AND blue

[striped, spotted, checkered, etc]R1R1 = blue

COLOR THE IMAGES ON YOUR LECTURE NOTES

Page 8: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Multiple AllelesMultiple Alleles

trait is coded for by more than 2 alleles for the SAME gene [same letter!!]

more combinations for the same traitgene can have:

multiple dominant alleles – like codominant or incomplete dominance

multiple recessive alleles – all of which would be hidden by any dominant allele present

Page 9: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

MA Example - DiscussExample: three alleles for the “R” geneR = red R1 = white r = orange

What color phenotypes would result from each of the following genotypes? [assume co-dominance]

RR RR1 R1R1 RrR1r rr

redwhitewhite

red AND whiteredorange

Page 10: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Multiple Alleles – cont’dMultiple Alleles

ex: Blood Type – codominant multiple allele traitalleles = IA, IB & io

A and B are dominant, O is recessive

caps letter “I” lower-case letter “i”

Page 11: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

MA – Discuss So…if A [IA] and B [IB] are dominant,

and O [io]is recessive …which genotypes will give each blood-type

phenotype? [A, B, and O]

A blood: IA IA or IA io

B blood: IB IB or IB io

O blood: only io io

Page 12: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

NOTE

You MAY NOT do blood type as your multiple allele trait.

Your traits must ALL be able to be seen just by looking at your creature.

Page 13: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Polygene InheritancePolygene Inheritance

“poly” = manytraits are influenced by many genes

will have combinations of different lettersex: traits with ranges or many types

hair/eye/skin color, height, build, etc.

Page 14: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Polygene InheritancePolygene Inheritance

ex: A / G / R = red a / g / r = no redmore dominant alleles, more colorAa Gg Rr is darker red than Aa gg rr

Page 15: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceTypes of Chromosomes

Autosome = non-sex determining chromosome [1-22]“autosomal” trait =

trait on a non-sex chromosomeSex-Chromosome = X or Y,

chromosome pair #23“sex-linked” trait =

trait on the X or Y [sex] chromosome

Page 16: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceAutosomal Dominant

dominant trait on a non-sex chromosomeheterozygotes [Aa] and

dominant homozygotes [AA] have the traitchildren with trait have at least

one parent with the traitaffects males and females equally

Page 17: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceAutosomal Recessive

recessive trait on a non-sex chromosomemust be recessive homozygote [aa] to have the

traitchildren with trait have parents who either

show or carry the traitcarrier – heterozygote person for a recessive

trait – does not show it, but has the allele [Aa]if both parents have the trait,

ALL children will have the trait

Page 18: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceAutosomal Recessive

affects males and females equallytraits often skip generations

Page 19: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceSex-linked Dominant [XA]

dominant trait on a sex chromosome typically on the X-chromosome many are fatal [especially in males]if both parents have trait, most children will

have it¾ of children if heterozygous motherall children if homozygous mother

affects males and females equallyif both parents have it, all kids have it.

Page 20: Unit 4 – Lecture 7. Review Mendellian / Single-Gene Inheritance two alleles per gene = 1 dominant, 1 recessive ex: R = red, r = blue RR = red Rr = red.

Naming InheritanceSex-linked Recessive [Xa]

recessive trait on a sex-chromosometypically on the X-chromosome females can be carriers; males cannotaffects more males than females

son with trait can have parents who don’t show trait

no father to son transmission of traittraits often skip generations