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Unit 12 Mitosis and Meiosis

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    Science Interactive LTD

    Science Interactive LTD. PO BOX 50764 LONDON NW6 9AT email: [email protected] web: www:science-interactive.co.uk

    Science Interactive LTD Copyright 2005

    Science base multimedia CD-ROM forPC is a collection of38 units or tools totalling over1150

    PowerPoint slides. Each unit covers a wide range of different delivery and learning styles, offering an

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    Unit 19: The Transitional Metals

    Unit 18: Metals and their Properties

    Unit 17: The Alkali Metals

    Unit 16: The Periodic Table and its Elements

    Unit 15: Genetic Engineering

    Unit 14: Evolution and Human Impact

    Unit 13: Inheritance and Selection

    Unit 12: Mitosis and Meiosis

    Unit 11: Flow of Energy and Elements through the Environment

    Unit 10: Water Transport in Plants

    Unit 9: Photosynthesis in Green Plants

    Unit 8: Drugs and Bad Body Maintenance

    Unit 7: Hormones and the Endocrine System

    Unit 6: Human Homeostasis

    Unit 5: Nervous System and the Senses

    Unit 4: The Respiratory System

    Unit 3: Healthy Body and Immunity

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    Unit 38: Cells, Tissue, Organs and Organs systems

    Unit 37: Natural Forces

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    Unit 35: The Alkaline Earth Metals

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    Unit 33: Earth and Space

    Unit 32: Newton's Forces and the Effects of Forces

    Unit 31: Radioactivity

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    Unit 29: Electricity

    Unit 28: Generating Electricity and its Domestic Use

    Unit 27: Energy

    Unit 26: Rates of Reaction

    Unit 25: The Noble Gases, their Properties and Uses

    Unit 24: The Halogens, their Uses and Compounds

    Unit 23: Ionic and Covalent Compounds

    Unit 22: Elements, Molecules and Compounds

    Unit 21: Rock Cycle

    Unit 20: Crude Oil and its Products

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    z Unit 12

    z Mitosis and Meiosis

    Mitosis Meiosis

    Parent cell

    & replicates

    2 daughter cells

    4 daughter cells

    DNA mixes

    Parent cell

    2 Daughter cells

    DNA replicates

    Chromosomesseparate

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    Unit 12: Mitosis and MeiosisUnit 12: Mitosis and Meiosis Science Interactive LTD Copyright 2005

    Understand: Keywords:

    1. That lost or damaged cells need to replaced inthe human body by mitosis.

    2. That mitosis is how organisms like humansgrow during pregnancy, through puberty toadult life.

    3. That meiosis in humans leads to the productionof the sperm and egg cells.

    4. That during meiosis, the number ofchromosomes in both the sperm and the eggcells are halved.

    5. That during meiosis, random crossing ofpaternal and maternal DNA takes placeproducing genetically unique sperm and ovum.

    6. That this random crossing during meiosis leadsto variation in both the genotype andphenotype of humans.

    7. How the sex of an individual is determined bythe chromosomes we inherit from our parents.

    Inheritance, Genes, Chromosomes, Alleles,

    Mitosis, Meiosis, Sperm, Ovum, Cells,

    Division, Clones, Reductive, Traits, Gametes,

    Variation, Characteristics, Recessive,

    Dominant, Genetic, Crosses, Diploid &

    Haploid.

    web: www.science-interactive.co.uk email: [email protected] Interactive LTD PO BOX 50764 LONDON NW6 9AT

    Click mouse to begin

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    Numbers of cellsNumbers of cells

    Cells are the building blocks of all life. Unlike simple bacteria and other unicellular organisms,

    living organisms contain from many millions to billions of cells. Cells can have a very wide

    range of f___________ in the human body from skin cells, blood cells, muscle cells to nerve

    cells. Cells can only be viewed using a light microscope. Robert Hook was the first scientist to

    observe plant and animal cells using a simple light m___________ over 300 years ago.List the

    cell types that you have observed under a light microscope ?

    Numbers of cells in living organisms:

    A small mammal, for

    example a rat contains

    many millions of cells

    organised into ninedistinct organ system

    similar to our own. List

    these organ systems ?

    Small mammal

    A human contains many

    billions of cells. Each

    hour of every day of our

    lives, we replace overone billion cells in our

    body. During puberty we

    produce even more cells.

    A typical insect like a fly

    or a bee contains many

    hundreds of thousands of

    cells. Insects have verybasic organ systems that

    support life and allow

    insects to reproduce.

    A bacteria is a simple

    single celled organism.

    All the bacteria found

    on the surface of thisplanet weigh more than

    any other species. They

    are very successful.

    Notes

    Diagram

    Organism Bacteria Insect Human

    Word bank: functions microscope

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    Essential cell organellesEssential cell organellesCell organelles, like mitochondria and chloroplasts carry out important functions in plant and

    animal cells. The n_________ controls the activity of the cell by building new proteins

    including enzymes. It also contains DNA, the material of inheritance and is able to divide andproduce new daughter cells during cell division or mitosis. Mitochondria found in both plant

    and animal cells respire glucose with o__________ releasing cellular e_________, carbon

    dioxide and water. Chloroplasts found only in plant cells produce glucose and oxygen from

    carbon dioxide and water !

    Cell organelles in plants and animals:Word bank: nucleus oxygen energy

    The cells nucleus

    contains the necessary

    genetic information or

    genes to produce newcells, new enzymes and

    new proteins. Humans

    have over 31,000 genes.

    Nucleus

    The cell membrane

    controls the passage of

    substances in and out of

    the cell. Movement ofmolecules happens by

    passive diffusion or

    active uptake.

    Found only in plant cells,

    chloroplast are able to

    combine carbon dioxide

    and water using theenergy from light to

    produce glucose and

    oxygen.

    Mitochondria are found

    in both plant and animal

    cells. They respire

    glucose with oxygen torelease energy for

    cellular activities. They

    release CO2 and water.

    Function

    Diagram

    Organelle Mitochondria Chloroplast Cell membrane

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    Specialised cells in animalsSpecialised cells in animalsCells are designed for the specific function they play in the human body as part of the billions

    of cells that work to together to support life. A nerve cellfor example is long and t_____ and

    conducts e__________ impulses. A red blood cell has a large surface area and no n________so it can transport the maximum amount of oxygen from the lungs to the rest of the body. A

    muscle cells contains many more mitochondrial organelles than normal cells and are able to

    contract producing movement. How is a sperm specialised to perform its function ...List three

    things ?

    Specialised cells in animals: Word bank: thin electrical nucleus

    Sperm cells can propel

    themselves locating the

    female egg cell prior to

    fertilisation as well as

    carrying paternal DNA.

    They also have a

    streamlined head.

    Sperm cell

    Muscle cells contract

    providing movement.

    They are also rich in

    mitochondria. This

    allows them to respire

    glucose with oxygen

    producing energy.

    Nerve cells form

    connections with other

    nerve cells, carry

    impulses along a huge

    neural network that

    connect and coordinate

    our actions and thoughts.

    Red blood cells contain

    haemoglobin, have a

    biconcave shape and no

    nucleus. They carry

    oxygen from the lung

    surface to the rest of the

    body

    Notes

    Diagram

    Cell Red blood cell Nerve cell Muscle cells

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    py g

    Specialised cells in plantsSpecialised cells in plantsAs in animals, plant cells are also designed for the function they play as part of the millions of

    cells that work together to support life and produce food in green plants. A root hair cell, for

    example is long and extremely thin to aid the uptake of w_______ and dissolved minerals likenitrates and phosphates from the s______. The leaf palisade cell contains many chloroplast

    organelles which during photosynthesis produces glucose and o________ from carbon dioxide

    and water. Which other cells have large surface areas to aid absorption ?

    Specialised cells in plants:Word bank: water sun oxygen

    Pollen cells, the male

    gametes in plants are

    normally transferred to

    the female carpel by

    insects. Pollen carries

    the genetic information

    to create a new plant.

    Pollen cell

    Stomata cells found on

    the underside of green

    leaves allows the

    exchange of water,

    carbon dioxide and

    oxygen through the leaf

    during photosynthesis.

    Water moves up the

    stem through the xylem

    vessels. They are long

    tubes reaching from the

    roots to the leaf tissue.

    Water moves in xylem

    cells by capillary action.

    Green leaves contain

    many palisade cells

    which are rich in

    chloroplasts that enable

    photosynthesis to occur.

    Why do root cells not

    have these cell parts ?

    Notes

    Diagram

    Cell Palisade cells Xylem cells Stomata cell

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    Cell size in plants and animalsCell size in plants and animalsCells in plants and animals vary in size. To visualize plant or animal cells we need to use a

    m___________. Animal cells on average, tend to be smallerand less regular in shape, when

    compared to plant cells. Both plant and animal cells grow and divide before becoming toolarge. Cells that are too large will have a reducedsurface area to volume ratio. A small surface

    area to volume ratio reduces the amount of o__________ and nutrients that can be absorbed

    across its surface membrane. Cells must then divide or die. This is called mitosis.

    Cell size and mitosis: Word bank: microscope oxygen

    Mitosis

    Parent cell

    2 Daughter cells

    DNA replicates

    Chromosomesseparate

    Stage one

    Stage four

    Stage two

    Stage three

    2n

    2n

    4n

    2n

    As the cell volume increases, the ratio of surface

    area to volume ratio deceases reducing the cells

    ability to allow sufficient nutrients and oxygen

    across the cell membrane. Cells are able to divideand clone themselves during mitosis. Over a billion

    cells an hour are replaced in your body by cells

    dividing.

    Cell division in plants and animals

    Photograph of plant

    palisade cells. They are

    magnified 100 times.

    Find their size using thesame method. Are they

    smaller or larger than

    human cheek cells ?

    Photograph of human

    cheek cells. They are

    magnified 250 times.

    Use a ruler to measuretheir length. Now divide

    by 250 to find their real

    size.

    Notes

    Diagram

    Cell Typical animal cells Typical plant cells

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    Mitosis for replacing cellsMitosis for replacing cellsNew cells are needed for you to grow and repair. These are made by cell divisions

    called mitosis. During mitosis, a cell d_________ and forms two identical clone cells.

    The human body produces up to one billion cells like this every hour replacing old

    worn out cells. New s______, muscle, blood, and nerve cells are all produced this

    way. Some species reproduce using mitosis. Bacteria, for example multiply using

    mitosis. What are the advantages of reproducing asexually ?

    Replacing cells by mitosis: Word bank: division skin

    Embryo grow by

    cloning cells. A

    single zygote leads

    to the formation of

    an embryos many

    millions of cells

    during pregnancy.

    Embryo growth

    Skins cells are lost

    and replaced due to

    normal wear and

    tear by mitosis.

    Every day we lose

    about 100 million

    skin cells.

    New skin cells

    Bacteria reproduce

    multiply and spread

    by cloning them-

    selves. Each cell is

    identical to the

    original bacterial

    cell.

    Bacteria

    Notes

    Diagram

    A human contains

    many billions of

    cells. Each hour

    of every day, we

    replace over one

    billion cells in our

    body.

    Human

    Blood cells last

    only about 90

    days before they

    need to be

    replaced by the

    marrow of the

    long bones.

    Blood cells

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    MitosisMitosis Normal cell divisionNormal cell division

    Mitosis occurs during growth and repair. Mitosis leads to formation of new identical

    cells. Producing c______ or identical cells has several advantages. They behave just

    like the old ones and they dont require anything but the original cell. What other

    advantages are there to producing identical clone cells ?

    Stages in mitosis: Word bank: clone

    Mitosis

    Parent cell

    2 Daughter cells

    DNA replicates

    Chromosomesseparate

    Stage one

    Stage four

    Stage two

    Stage three

    2n

    2n

    4n

    2n

    Mitosis in plants

    Notes

    Diagram

    Stage one: Chromosomes become visible and double inside the nucleus. The cell now contains 46 pairs of

    chromosomes. Stage two:The chromosomes move to the centre and line up before separation. Stage three:

    Each set of chromosomes separates moving to the cell poles before cell division. Stage four: The celldivides, producing two clone cells each containing 23 pairs of chromosomes. In the shoots and tips of plants

    new cells are formed during mitotic cell divisions. Each daughter cell is identical to the original cell. This

    picture shows several cells in various stages of mitosis.

    Mitosis (normal cell division)

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    MeiosisMeiosis gametes in humansgametes in humansMeiosis leads to the formation of only two types of cells. Meiosis in males forms the

    s______ and in females the o______ or egg cells. Meiosis halves the number of

    chromosomes, so that when the sperm and egg fuse, the fertilised zygote will have thecorrect number of chromosomes (23 chromosomal pairs). Meiosis also produces random

    gene mixingleading to variation of human traits in new individuals.

    Gamete production in the male and female:

    sperm

    egg

    Word bank: sperm ovum

    All of these 31,000 genes

    code for all the traits and

    characteristics that makehuman life unique. Cells

    now divide by mitosis.

    After fertilisation, all

    cells of the developing

    embryo now contain 23pairs of chromosomes

    with over 31,000 genes.

    Sperm and egg cells are

    haploid with only 23

    single chromosomesonly half the normal

    number

    Gametes cells (sperm

    and egg) are produced

    by the testis andovaries in the male

    and female.

    PregnancyEmbryoFertilisationGametes

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    MeiosisMeiosis Reductive cell divisionReductive cell division

    During meiosis, the number of chromosomes are halved so that the s______ and egg

    carries 23 single chromosomes. During meiosis, paternal genes that code for your

    characteristics randomly mix, so that we are all not the same. Name the cells in plantsthat are produces by the process of meiosis ?

    Stages in meiosis: Word bank: sperm

    Sperm production

    Notes

    Diagram

    Stage 1: Chromosomes double and randomly mix inside the nucleus. The cell now contains 46 pairs of

    chromosomes. Stage 2:The chromosomes move to the centre and line up before separation. Stage 3: The

    cell divides, producing two new cells each containing 23 pairs of chromosomes. Stage 4: The two daughtercells divide again halving the number of chromosomes. Each gamete now contains only 23 single

    chromosomes. A sperm cell carries 23 single chromosomes and fuses with an egg cell which also carries 23

    single chromosomes to form a zygote, which now carries the normal diploid number of chromosomes.

    Meiosis (reductive cell division)

    Meiosis

    Stage one

    Stage four

    Stage two

    Stage three

    2n

    n

    4n

    2n

    Parent cell

    & replicates

    2 daughter cells

    4 daughter cells

    DNA mixes

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    M i iMeiosis Determining sex by chromosomesDetermining sex by chromosomes

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    MeiosisMeiosis Determining sex by chromosomesDetermining sex by chromosomes

    Your chromosomes also determine what sex you are at b_______. In humans there are

    23pairs of chromosomes found in every cell. 22pairs are identical, butpair23 do not

    match.Pair23 are called the sex chromosomes. All eggs from the female contain theX chromosome, sperm from the male contain either the X or Y chromosome. At

    f_____________, the egg may join with either an X or Y sperm producing equal

    numbers of males (XY) or females (XX). What are the gametes cells called in plants ?

    Inheritance of the sex chromosomes:

    XX

    Female

    XY

    Male

    Egg

    SpermXX

    Female

    XY

    Male

    Egg

    Sperm

    Word bank: birth fertilisation

    During fertilisation, the number of

    chromosomes are restored to theirnormal diploid number (23 pairs) The

    embryo now grows by normal cell

    division called mitosis.

    The gamete cells

    (sperm and egg) carryonly 23 single

    chromosomes. They

    are haploid cells.

    Your sex is determined at the moment

    of fertilisation by the male sperm. AnX carrying sperm produces a girl, and a

    Y carrying sperm produces a boy.

    There is a 50: 50 chance of either sex.

    Sex inheritanceGamete cellsFemaleMale

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    M i iMeiosis gametes in plantsgametes in plants

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    MeiosisMeiosis gametes in plantsgametes in plants

    Pollination is the transfer of pollen, the male sex cells from the a_________ of the stamen by

    b____ or insects to the surface of the female c_________. Once the pollen sex cells have

    landed on the female carpel, pollination has been achieved. Flowering plants contain bothfemale and male reproductive organs and can either self or cross pollinate. Following

    fertilisation, where the ovule and pollen cell fuse, the seed begins to develop surrounded by the

    swollen ovule which forms the f_______. It is the function of the fruit to disperse the seed.

    What is this organs role in the plant life cycle ?

    Plant reproductive system: Word bank: anther bees carpel fruit

    The stamen is the plant

    male reproductive organ

    which contains manymillions of microscopic

    pollen cells.

    Male anther

    Flowering plants have

    both male and female

    reproductive organs.Plants can self or cross

    pollinate.

    The egg cells or ovules

    contain the maternal

    genes and are held in theovule, part of the female

    carpel.

    Pollen, the male sex

    cells contain the paternal

    genes and are held onthe anther which is part

    of the male stamen.

    Notes

    Diagram

    Pollen cells Female carpel Reproductive system

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    M i iM i i Variation in humansVariation in humans oneone

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    MeiosisMeiosis Variation in humansVariation in humans oneone

    Humans have many of their genes which are common to us all. Over99% of our genes

    in all the races are shared. Only 1% of human g_______ are unique and different.

    These genes code for differences in the colour of skin, eyes, hair and other features

    like the shape of our faces. Unless youre an identical twin, your genes, your traits and

    you are unique amongst the other5.5billion human beings found on this planet. What

    are the advantages of variation in a species like humans ?

    Variation in humans:

    Variation in humans (traits such as skin and eye colour) occur due to the random mixing ofDNA during meiosis ensuring that no egg or sperm carry exactly the same genes or DNA and

    of course during fertilisation, when the genes from your mother and father mix to form you.

    Notes

    Japanese MaoriArab

    Diagram

    Masai warrior Aborigine

    Word bank: genes

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    M i iMeiosis Variation in humansVariation in humans twotwo

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    MeiosisMeiosis Variation in humansVariation in humans twotwo

    Variation in the human race is caused by differences in your genes, caused by the

    random m______ ofDNA during the production of sperm and egg and of course when

    the genes from your father and mother join during fertilisation. Your mother and

    father both share exactly 50% of yourDNA and are your closest biological relatives.

    Brothers and sisters can share up to 50% of theirDNA, but the figure is usually only

    around 25%. Why do brothers and sisters look very similar to one another ?

    Variation in humans:

    Look around you in class, we all have certain similarities, but we are all unique. We belong

    to the same species, can reproduce with one another but are all different. Some people are

    taller or heavier or have different colour hair, skin or eyes. This is called variation. This is

    because we all have different genes in our cells from our parents.

    Notes

    South American Europe (south)Asian

    Diagram

    African Europe (North)

    Word bank: mixing

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    Extension questions and homework

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    Extension questions and homework

    1: Define the following terms: Chromosome, Gene, Allele, Characteristic, Diploid, Haploid, Trait, Genotype,

    Phenotype, Mutation, Recessive and Dominant.

    2: Look at the three pictures below. Complete the table:

    3: Answer the following:

    a) Give 3 examples of human traits or characteristics

    b) Give 3 examples of traits or characteristics in plants.

    c) Name two cells that have a diploid number of chromosomes and two cells that have a haploid number of

    chromosomes. Do any cells in humans have no chromosomes.

    d) From the following, decide whether each cell is the result of mitotic or meiotic cell division.

    Description

    Production of sperm and egg

    Plant cells dividing at shoot tip

    Embryo growing during pregnancy

    Mitosis/MeiosisPicture

    BacteriaSpermMuscle cellPollenPlant ovumSperm cellSkin cellBlood cell

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    4: The diagram below shows how the sex of a child is determined by the chromosomes inherited from both parents

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    4: The diagram below shows how the sex of a child is determined by the chromosomes inherited from both parents.

    (a) All human cells contain 46 chromosomes. How many chromosomes are there in

    human egg or sperm cells.

    (b) Explain why either a daughter or a son will share some of the characteristics

    from both parents.

    (c) Explain why your parents are your closest living relatives.

    (d) What type of cell division leads to the formation of an embryo from a zygote

    during pregnancy.

    5: Chromosomes occur in pairs in all cells except gametes.

    (a) What are alleles

    (b) Why are there two alleles for each characteristic.

    (c) Explain what is meant by dominant and recessive alleles.

    (d) The characteristics of humans are either inherited, or are caused by environmental influences. [Blood group,

    Weight, Eye-colour, Gender and Accidental loss of arm]

    (i) Which features are controlled by environmental influences (ii) Name one that is controlled by inheritance only

    (iii) One that is controlled by both.

    6: A plant can either self or cross pollinate. Answer the following questions:

    (a) Which process (self or cross) leads to the production of (i) Identical offspring (ii) Different offspring.

    (b) List the advantages and disadvantages of asexual and sexual reproduction in plants.

    XX

    Female

    XY

    Male

    Egg

    Sperm XX

    Female

    XY

    Male

    Egg

    Sperm

    Internet:

    Go to google.co.uk and find about how cloning in plants is used by commercial growers to improve the quality andyield of a particular crop. Are there any disadvantages to cloning plants for commercial reasons.