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1 Unit 1: What is Biology? Unit 2: Ecology Unit 3: The Life of a Cell Unit 4: Genetics Unit 5: Change Through Time Unit 6: Viruses, Bacteria, Protists, and Fungi Unit 7: Plants Unit 8: Invertebrates Unit 9: Vertebrates Unit 10: The Human Body Unit 1: What is Biology? Chapter 1: Biology: The Study of Life Unit 2: Ecology Chapter 2: Principles of Ecology Chapter 3: Communities and Biomes Chapter 4: Population Biology Chapter 5: Biological Diversity and Conservation Unit 3: The Life of a Cell Chapter 6: The Chemistry of Life Chapter 7: A View of the Cell Chapter 8: Cellular Transport and the Cell Cycle Chapter 9: Energy in a Cell Unit 4: Genetics Chapter 10: Mendel and Meiosis Chapter 11: DNA and Genes Chapter 12: Patterns of Heredity and Human Genetics Chapter 13: Genetic Technology Unit 5: Change Through Time Chapter 14: The History of Life Chapter 15: The Theory of Evolution Chapter 16: Primate Evolution Chapter 17: Organizing Life’s Diversity Unit 6: Viruses, Bacteria, Protists, and Fungi Chapter 18: Viruses and Bacteria Chapter 19: Protists Chapter 20: Fungi Unit 7: Plants Chapter 21: What Is a Plant? Chapter 22: The Diversity of Plants Chapter 23: Plant Structure and Function Chapter 24: Reproduction in Plants Unit 8: Invertebrates Chapter 25: What Is an Animal? Chapter 26: Sponges, Cnidarians, Flatworms, and Roundworms Chapter 27: Mollusks and Segmented Worms Chapter 28: Arthropods Chapter 29: Echinoderms and Invertebrate Chordates
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Unit 1: What is Biology?

Unit 2: Ecology

Unit 3: The Life of a Cell

Unit 4: Genetics

Unit 5: Change Through Time

Unit 6: Viruses, Bacteria, Protists, and Fungi

Unit 7: Plants

Unit 8: Invertebrates

Unit 9: Vertebrates

Unit 10: The Human Body

Unit 1: What is Biology?

Chapter 1: Biology: The Study of Life

Unit 2: Ecology

Chapter 2: Principles of Ecology

Chapter 3: Communities and Biomes

Chapter 4: Population Biology

Chapter 5: Biological Diversity and Conservation

Unit 3: The Life of a Cell

Chapter 6: The Chemistry of Life

Chapter 7: A View of the Cell

Chapter 8: Cellular Transport and the Cell Cycle

Chapter 9: Energy in a Cell

Unit 4: Genetics

Chapter 10: Mendel and Meiosis

Chapter 11: DNA and Genes

Chapter 12: Patterns of Heredity and Human Genetics

Chapter 13: Genetic Technology

Unit 5: Change Through Time

Chapter 14: The History of Life

Chapter 15: The Theory of Evolution

Chapter 16: Primate Evolution

Chapter 17: Organizing Life’s Diversity

Unit 6: Viruses, Bacteria, Protists, and Fungi

Chapter 18: Viruses and Bacteria

Chapter 19: Protists

Chapter 20: Fungi

Unit 7: Plants

Chapter 21: What Is a Plant?

Chapter 22: The Diversity of Plants

Chapter 23: Plant Structure and Function

Chapter 24: Reproduction in Plants

Unit 8: Invertebrates

Chapter 25: What Is an Animal?

Chapter 26: Sponges, Cnidarians, Flatworms, and

Roundworms

Chapter 27: Mollusks and Segmented Worms

Chapter 28: Arthropods

Chapter 29: Echinoderms and Invertebrate

Chordates

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Unit 9: Vertebrates

Chapter 30: Fishes and Amphibians

Chapter 31: Reptiles and Birds

Chapter 32: Mammals

Chapter 33: Animal Behavior

Unit 10: The Human Body

Chapter 34: Protection, Support, and Locomotion

Chapter 35: The Digestive and Endocrine Systems

Chapter 36: The Nervous System

Chapter 37: Respiration, Circulation, and Excretion

Chapter 38: Reproduction and Development

Chapter 39: Immunity from Disease

Viruses, Bacteria, Protists, and Fungi

Viruses and Bacteria

Protists

Fungi

Chapter 18 Viruses and Bacteria

18.1: Viruses

18.1: Section Check

18.2: Archaebacteria and Eubacteria

18.2: Section Check

Chapter 18 Summary

Chapter 18 Assessment

What You’ll Learn

You will identify the structures and characteristics of viruses and bacteria.

You will explain how viruses and bacteria reproduce.

You will recognize the medical and economic importance of viruses and bacteria.

• Identify the different kinds of viruses and their structures.

Section Objectives:

• Compare and contrast the replication cycles of viruses.

• You’ve probably had the flu—influenza—at some time during your life.

• Viruses are composed of nucleic acids enclosed in a protein coat and are smaller than the smallest bacterium.

What is a virus?What is a virus?

• Nonliving particles called viruses cause influenza.

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• Most biologists consider viruses to be nonliving because they don’t exhibit all the criteria for life.

• They don’t carry out respiration, grow, or develop. All viruses can do is replicate—make copies of themselves—and they can’t even do that without the help of living cells.

What is a virus?What is a virus?

• A cell in which a virus replicates is called the host cell.

• Viruses, such as rabies viruses and polioviruses, were named after the diseases they cause.

• Other viruses were named for the organ or tissue they infect.

What is a virus?What is a virus?

What is a virus?What is a virus?

• Today, most viruses are given a genus name ending in the word “virus” and a species name.

• However, sometimes scientists use code numbers to distinguish among similar viruses that infect the same host.

• A virus that infects a bacterium is called a bacteriophage (bak TIHR ee uh fayj), or phage for short.

Viral StructureViral Structure• A virus has an

inner core of nucleic acid, either RNA or DNA, and an outer protein coat called a capsid.

Capsid

Nucleic

acid

Envelope

Viral StructureViral Structure• Some relatively

large viruses, such as human flu viruses, may have an additional layer, called an envelope, surrounding their capsids.

Capsid

Nucleic

acid

Envelope

Viral StructureViral Structure

• Envelopes are composed primarily of the same materials found in the plasma membranes of all cells.

Capsid

Nucleic

acid

Envelope

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• Viral nucleic acid is either DNA or RNA and contains instructions for making copies of the virus.

• Some viruses have only four genes, while others have hundreds.

Nucleic acid

Capsid

Viral StructureViral Structure

• The tobacco mosaic virus has a long, narrow helical shape.

Nucleic acid

Capsid

Viral StructureViral Structure

Viral StructureViral Structure• The arrangement of

proteins in the capsid of a virus determines the virus’s shape.

Nucleic acidCapsid

• Polyhedral viruses resemble small crystals.

Viral StructureViral Structure

• The protein arrangement also plays a role in determining what cell can be infected and how the virus infects the cell.

Nucleic acidCapsid

Attachment to a host cellAttachment to a host cell

• Before a virus can replicate, it must enter a host cell.

• A virus recognizes and attaches to a host cell when one of its proteins interlocks with a molecular shape that is the receptor site on the host cell’s plasma membrane.

Attachment to a host cellAttachment to a host cell

• A protein in the tail fibers of the bacteriophage T4 recognizes and attaches the T4 to its bacterial host cell.

Capsid

Nucleic acid

Tail

Tail fiber

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Attachment to a host cellAttachment to a host cell

• In other viruses, the attachment protein is in the capsid or in the envelope.

Capsid

Nucleic acid

Tail

Tail fiber

Attachment is a specific processAttachment is a specific process

• Each virus has a specifically shaped attachment protein. Therefore, each virus can usually attach to only a few kinds of cells.

• In general, viruses are species specific, and some also are cell-type specific. For example, polio viruses normally infect only intestinal and nerve cells.

Attachment is a specific processAttachment is a specific process

• The species specific characteristic of viruses is significant for controlling the spread of viral diseases.

Viral Replication CyclesViral Replication Cycles

• Once attached to the plasma membrane of the host cell, the virus enters the cell and takes over its metabolism.

• Only then can the virus replicate.

• Viruses have two ways of getting into host cells.

Viral Replication CyclesViral Replication Cycles

• The virus may inject its nucleic acid into the host cell like a syringe injects a vaccine into your arm.

• The capsid of the virus stays attached to the outside of the host cell.

• An enveloped virus enters a host cell in a different way.

Viral Replication CyclesViral Replication Cycles

• After attachment, the plasma membrane of the host cell surrounds the virus and produces a virus-filled vacuole inside the host cell’s cytoplasm.

• Then, the virus bursts out of the vacuole and releases its nucleic acid into the cell.

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Lytic cycleLytic cycle

• Once inside the host cell, a virus’s genes are expressed and the substances that are produced take over the host cell’s genetic material.

• The viral genes alter the host cell to make new viruses.

Nucleic acid

Bacterial host cell

Bacteriophage Bacterial DNA

B. Entry

The bacteriophage

injects its nucleic acid into the bacterial cell.

A. Attachment

C. ReplicationD. Assembly

E. Lysis and Release

The host’s metabolic

machinery makes viral

nucleic acid and proteins.

New virus particles

are assembled.

The host cell breaks open and

releases new virus particles.

Lytic cycleLytic cycle

Lytic cycleLytic cycle

• The host cell uses its own enzymes, raw materials, and energy to make copies of viral genes that along with viral proteins are assembled into new viruses, which burst from the host cell, killing it.

Lytic cycleLytic cycle

• The new viruses can then infect and kill other host cells. This process is called a lytic (LIH tik) cycle. Click image to play movie

Lysogenic cycleLysogenic cycle

• Not all viruses kill the cells they infect.

• Some viruses go through a lysogenic cycle, a replication cycle in which the virus’s nucleic acid is integrated into the host cell’s chromosome.

Click image to play movie

Lysogenic cycleLysogenic cycle

• A lysongenic cycle begins in the same way as a lytic cycle.

• However, in a lysogenic cycle, instead of immediately taking over the host’s genetic material, the viral DNA is integrated into the host cell’s chromosome.

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Lysogenic cycleLysogenic cycle Disease symptoms of provirusesDisease symptoms of proviruses

• Many disease-causing viruses have lysogenic cycles.

• Three examples of these viruses are herpes simplex I, herpes simplex II that causes genital herpes, and the hepatitis B virus that causes hepatitis B.

Disease symptoms of provirusesDisease symptoms of proviruses

• Another lysogenic virus is the one that causes chicken pox.

Disease symptoms of provirusesDisease symptoms of proviruses

• Having chicken pox, which usually occurs before age ten, gives lifelong protection from another infection by the virus. However, some chicken pox viruses may remain as proviruses in some of your body’s nerve cells.

Disease symptoms of provirusesDisease symptoms of proviruses

• Later in your life, these proviruses may enter a lytic cycle and cause a disease called shingles—a painful infection of some nerve cells.

Release of virusesRelease of viruses

• Either lysis, the bursting of a cell, or exocytosis, the active transport process by which materials are expelled from a cell, release new viruses from the host cell.

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Release of virusesRelease of viruses

• In exocytosis, a newly produced virus approaches the inner surface of the host cell’s plasma membrane.

• The plasma membrane surrounds the virus, enclosing it in a vacuole that then fuses with the host cell’s plasma membrane.

• Then, the viruses are released to the outside.

RetrovirusesRetroviruses

• Many viruses, such as the human immunodeficiency virus (HIV) that causes the disease AIDS, are RNA viruses—RNA being their only nucleic acid.

HIV virus

RetrovirusesRetroviruses

• Once inside a human host, HIV infects white blood cells.

• Newly made viruses are released into the blood stream by exocytosis and infect other white blood cells.

Normal white blood cells

HIV: An infection of white blood cellsHIV: An infection of white blood cells

HIV: An infection of white blood cellsHIV: An infection of white blood cells

• Infected host cells still function normally because the viral genetic material is a provirus that produces only a small number of new viruses at a time.

• Because the infected cells are still able to function normally, an infected person may not appear sick, but they can still transmit the virus in their body fluids.

HIV: An infection of white blood cellsHIV: An infection of white blood cells

• Most people with an HIV infection eventually get AIDS because, over time, more white blood cells are infected and produce new viruses.

• Because white blood cells are part of a body’s disease-fighting system, their destruction interferes with the body’s ability to protect itself from organisms that cause disease, a symptom of AIDS.

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Cancer and VirusesCancer and Viruses

• Some viruses have been linked to certain cancers in humans and animals.

• These viruses disrupt the normal growth and division of cells in a host, causing abnormal growth and creating tumors.

Prions and viroidsPrions and viroids

• Researchers have recently discovered some particles that behave somewhat like viruses and cause infectious diseases.

• Prions are composed of proteins but have no nucleic acid to carry genetic information.

Prions and viroidsPrions and viroids

• Prions are thought to act by causing other proteins to fold themselves incorrectly, resulting in improper functioning.

• Prions are responsible for many animal diseases, such as mad cow disease and its human equivalent, Creutzfeldt-Jakob disease.

Prions and viroidsPrions and viroids

• Viroids are composed of a single circular strand of RNA with no protein coat.

• Viroids have been shown to cause infectious diseases in several plants.

• The amount of viroid RNA is much less than the amount found in viruses.

Plant virusesPlant viruses

• The first virus to be identified was a plant virus, called tobacco mosaic virus, that causes disease in tobacco plants.

Tobacco mosaic virus causes yellow spots on tobacco leaves, making them unmarketable.

Plant virusesPlant viruses

• Viruses cause as many as 1000 plant diseases and are named according to their host plant.

• Viruses can cause stunted growth and yield losses in their host plants.

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Plant virusesPlant viruses

• Plant viruses require wounds or insect bites to enter and infect a host, and do not use surface recognition.

• They do not undergo lytic or lysogenic phases.

Plant virusesPlant viruses

• Not all viral plant diseases are fatal or even harmful.

• Some mosaic viruses cause striking patterns of color in the flowers of plants.

Rembrandt tulips

Origin of VirusesOrigin of Viruses

• For replication, viruses need host cells; therefore, scientists suggest that viruses might have originated from their host cells.

• Some scientists suggest that viruses are nucleic acids that break free from their host cells while maintaining an ability to replicate parasitically within the host cells.

Question 1

Which of the following is NOT a reason that viruses are considered to be nonliving?

D. Viruses don’t develop.

C. Viruses don’t grow.

B. Viruses don’t respire.

A. Viruses don’t replicate.

The answer is A.

Question 2

Which is NOT a component of a virus?

D. phage

C. DNA

B. capsid

A. RNA

The answer is D.

Question 3

Which of the following is NOT determined by the arrangement of proteins in the capsid of a virus?

D. how the virus infects a cell

C. whether or not the virus will have an envelope around it

B. what cell can be infected by the virus

A. shape

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The answer is C.Question 4

What two ways do viruses have of getting into host cells?

Answer

The virus can inject its nucleic acid into the host cell, or attach to the host cell’s membrane and become surrounded by the membrane and placed in a vacuole. The virus then bursts out of the vacuole and releases its nucleic acid into the cell.

Question 5

In the lytic cycle, after the host’s metabolic machinery makes viral nucleic acid and proteins the next phase is _______.

D. attachment

C. assembly

B. replication

A. lysis and release

The answer is C. In the assembly phase, the new virus particles are assembled.

Section Objectives

• Explain the characteristics and adaptations of bacteria.

• Compare the types of prokaryotes.

• Evaluate the economic importance of bacteria.

• Recall that prokaryotes are unicellular organisms that do not have a nucleus or membrane-bound organelles.

Diversity of ProkaryotesDiversity of Prokaryotes

• They are classified in two kingdoms—archaebacteria and eubacteria.

• Many biochemical differences exist between these two types of prokaryotes.

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• Because they are so different, many scientists propose that archaebacteria and eubacteria arose from a common ancestor several billion years ago.

Diversity of ProkaryotesDiversity of Prokaryotes

• There are three types of archaebacteria that live mainly in extreme habitats where there is usually no free oxygen available.

Archaebacteria: The extremistsArchaebacteria: The extremists

• One type of archaebacterium lives in oxygen-free environments and produces methane gas.

• These methane-producing archaebacteria live in marshes, lake sediments, and the digestive tracts of some mammals, such as cows.

Archaebacteria: The extremistsArchaebacteria: The extremists Archaebacteria: The extremistsArchaebacteria: The extremists

• They also are found at sewage disposal plants, where they play a role in the breakdown of sewage.

• A second type of archaebacterium lives only in water with high concentrations of salt.

Archaebacteria: The extremistsArchaebacteria: The extremists

Dead Sea

• A third type lives in the hot, acidic waters of sulfur springs.

Archaebacteria: The extremistsArchaebacteria: The extremists

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• This type of anaerobic archaebacterium also thrives near cracks deep in the ocean floor, where it is the autotrophic producer for a unique animal community’s food chain.

Archaebacteria: The extremistsArchaebacteria: The extremists

• Eubacteria, the other kingdom of prokaryotes, includes those prokaryotes that live in places more hospitable than archaebacteria inhabit and that vary in nutritional needs.

Eubacteria: The heterotrophsEubacteria: The heterotrophs

• The heterotrophic eubacteria live almost everywhere and use organic molecules as their food source.

• Some bacterial heterotrophs are parasites, obtaining their nutrients from living organisms.

Eubacteria: The heterotrophsEubacteria: The heterotrophs

• Others are saprophytes—organisms that feed on dead organisms or organic wastes.

• A second type of eubacterium is the photosynthetic autotroph.

Eubacteria: Photosynthetic autotrophsEubacteria: Photosynthetic autotrophs

• These eubacteria live in places with sunlight because they need light to make the organic molecules that are their food.

• Cyanobacteria are photosynthetic autotrophs.

Eubacteria: Photosynthetic autotrophsEubacteria: Photosynthetic autotrophs

• Most cyanobacteria are blue-green and some are red or yellow in color.

Cyanobacteria

Eubacteria: Photosynthetic autotrophsEubacteria: Photosynthetic autotrophs

• Cyanobacteria commonly live in ponds, streams, and moist areas of land.

• They are composed of chains of independent cells.

Cyanobacteria

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• A third type of eubacterium is the chemosynthetic autotroph.

Eubacteria: Chemosynthetic autotrophsEubacteria: Chemosynthetic autotrophs

• Unlike the photosynthetic bacteria, the chemosynthetic bacteria do not obtain the energy they need to make food from sunlight.

Eubacteria: Chemosynthetic autotrophsEubacteria: Chemosynthetic autotrophs

• Instead, they break down and release the energy of inorganic compounds containing sulfur and nitrogen in the process called chemosynthesis.

What is bacterium?What is bacterium?

• A bacterium consists of a very small cell.

• Although tiny, a bacterial cell has all the structures necessary to carry out its life functions.

The structure of bacteriaThe structure of bacteria

• Prokaryotic cells have ribosomes, but their ribosomes are smaller than those of eukaryotes.

• They also have genes that are located for the most part in a single circular chromosome, rather than in paired chromosomes.

The structure of bacteriaThe structure of bacteriaRibosome

Cytoplasm

Chromosome

Gelatinlike

capsuleCell Wall

Cell Membrane

Flagellum

A Typical Bacterial CellA Typical Bacterial Cell

• A typical bacterium, such as Escherichia coliwould have some or all of the structures shown in this diagram of a bacterial cell.

Capsule Cell Wall

Chromosome

Flagellum

PlasmidPilus

Plasma membrane

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The structure of bacteriaThe structure of bacteria

• A bacterial cell remains intact as long as its cell wall is intact.

• If the cell wall is damaged, water will enter the cell by osmosis, causing the cell to burst.

• Scientists used a bacterium’s need for an intact cell wall to develop a weapon against bacteria that cause disease.

The structure of bacteriaThe structure of bacteria

• In 1928, Sir Alexander Fleming accidentally discovered penicillin, the first antibiotic—a substance that destroys bacteria—used in humans.

The structure of bacteriaThe structure of bacteria

• Later, biologists discovered that penicillin can interfere with the ability of some bacteria to make cell walls.

• When such bacteria grow in penicillin, holes develop in their cell walls, water enters their cells, and they rupture and die.

Identifying bacteriaIdentifying bacteria

• One trait that helps categorize bacteria is how they react to Gram stain.

• Gram staining is a technique that distinguishes two groups of bacteria because the stain reflects a basic difference in the composition of bacterial cell walls.

• After staining, Gram-positive bacteria are purple and Gram-negative bacteria are pink.

Gram-positive bacteria Gram-negative bacteria

Identifying bacteriaIdentifying bacteria

• Gram-positive bacteria are affected by different antibiotics than those that affect Gram-negative bacteria.

Gram-positive bacteria Gram-negative bacteria

Identifying bacteriaIdentifying bacteria

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Identifying bacteriaIdentifying bacteria

• Bacterial cell walls also give bacteria different shapes.

• Shape is another way to categorize bacteria.

Identifying bacteriaIdentifying bacteria

• The three most common shapes are spheres, called coccus; rods, called bacillus; and spirals, called spirillum.

Identifying bacteriaIdentifying bacteria

• In addition to having one of these shapes, bacterial cells often grow in characteristic patterns that provide another way of categorizing them.

Identifying bacteriaIdentifying bacteria

• Diplo–is a prefix that refers to a paired arrangement of cell growth.

• The prefix staphylo–describes an arrangement of cells that resemble grapes.

• Strepto–is a prefix that refers to an arrangement of chains of cells.

Reproduction by binary fissionReproduction by binary fission

• Bacteria reproduce asexually by a process known as binary fission.

• To reproduce in this way, a bacterium first copies its chromosome. Then the original chromosome and the copy become attached to the cell’s plasma membrane for a while.

Reproduction by binary fissionReproduction by binary fission

• The cell grows larger, and eventually the two chromosomes separate and move to opposite ends of the cell.

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Reproduction by binary fissionReproduction by binary fission

• Then, a partition forms between the chromosomes. This partition separates the cell into two similar cells.

Reproduction by binary fissionReproduction by binary fission

• Because each new cell has either the original or the copy of the chromosome, the resulting cells are genetically identical.

Reproduction by binary fissionReproduction by binary fission

• Under ideal conditions, some bacteria can reproduce every 20 minutes, producing enormous numbers of bacteria quickly.

• But bacteria don’t always have ideal growing conditions. They run out of nutrients and water, they poison themselves with their own wastes, and predators eat them.

Sexual reproductionSexual reproduction

• In addition to binary fission, some bacteria have a form of sexual reproduction called conjugation.

• During conjugation (kahn juh GAY shun), one bacterium transfers all or part of its chromosome to another cell through or on a bridgelike structure called a pilus that connects the two cells.

Sexual reproductionSexual reproduction

• Conjugation results in a bacterium with a new genetic composition.

• This bacterium can then undergo binary fission, producing more cells with the same genetic makeup.

Adaptations in BacteriaAdaptations in Bacteria

• Based on fossil evidence, some scientists propose that anaerobic bacteria were probably among the first photosynthetic organisms, producing not only their own food but also oxygen.

• As the concentration of oxygen increased in Earth’s atmosphere, some bacteria probably adapted over time to use oxygen for respiration.

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Diversity of metabolismDiversity of metabolism

• Modern bacteria have diverse types of respiration.

• Many bacteria require oxygen for respiration. These bacteria are called obligate aerobes.

• There are other bacteria, called obligate anaerobes, that are killed by oxygen.

Diversity of metabolismDiversity of metabolism

• There are still other bacteria that can live either with or without oxygen, releasing the energy in food aerobically by cellular respiration or anaerobically by fermentation.

A survival mechanismA survival mechanism

• Some bacteria, when faced with unfavorable environmental conditions, produce endospores.

• An endospore is a tiny structure that contains a bacterium’s DNA and a small amount of its cytoplasm, encased by a tough outer covering that resists drying out, temperature extremes, and harsh chemicals.

A survival mechanismA survival mechanism

• When environmental conditions improve, the endospore germinates, or produces a cell that begins to grow and reproduce.

• Some endospores have germinated after thousands of years in the resting state.

• As an endospore, the bacterium rests and does not reproduce.

A survival mechanismA survival mechanism

• Endospores can survive a temperature of 100˚C, which is the boiling point of water.

A survival mechanismA survival mechanism

• To kill endospores, items must be sterilized—heated under high pressure in either a pressure cooker or an autoclave.

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A survival mechanismA survival mechanism

• This is because the endospores of the bacterium called Clostridium botulinumeasily get into foods being canned.

• Canned food must be sterilized and acidified.

A survival mechanismA survival mechanism

• Bacteria grow in the anaerobic environment of the can and produce a powerful deadly poison, called a toxin, as they grow.

• If the endospores of C. botulinum get into improperly sterilized canned food, they germinate.

• This deadly toxin saturates the food and, if eaten, causes the disease called botulism.

A survival mechanismA survival mechanism

• B. anthracis causes anthrax, a disease that commonly infects cattle and sheep, but can also infect humans.

• A different bacterium, Bacillus anthracis, lives in the soil.

• Most human anthrax infections are fairly harmless and occur on the skin as a result of handling animals.

A survival mechanismA survival mechanism

• This infection is more serious than a skin infection and often fatal.

• The bacterial spores can become airborne, however, and if inhaled in large amounts, can germinate in a person’s lungs, causing an infection.

The Importance of BacteriaThe Importance of Bacteria

• Bacteria help to fertilize fields, to recycle nutrients on Earth, and to produce foods and medicines.

• Disease-causing bacteria are few compared with the number of harmless and beneficial bacteria on Earth.

Nitrogen fixationNitrogen fixation

• Yet few organisms, including most plants, can directly use nitrogen from the air.

• All organisms need nitrogen because the element is a component of their proteins, DNA, RNA, and ATP.

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Nitrogen fixationNitrogen fixation

• Other bacteria then convert the ammonia into nitrite (NO2

–) and nitrate (NO3–),which plants

can use.

• Several species of bacteria have enzymes that convert N2 into ammonia (NH3) in a process known as nitrogen fixation.

• Bacteria are the only organisms that can perform these chemical changes.

Nitrogen fixationNitrogen fixation

• Farmers grow legume crops after the harvesting of crops such as corn, which depletes the soil of nitrogen.

• Some nitrogen-fixing bacteria live symbiotically within the roots of some trees and legumes.

Recycling of nutrientsRecycling of nutrients

• This food is passed from one heterotroph to the next in food chains and webs.

• Autotrophic bacteria and also plants and algae, which are at the bottom of the food chains, use the nutrients in the food they make.

• In the process of making food, many autotrophs replenish the supply of oxygen in the atmosphere.

Food and medicinesFood and medicines

• Some foods that you eat—mellow Swiss cheese, crispy pickles, tangy yogurt—would not exist without bacteria.

Food and medicinesFood and medicines

• Specific bacteria are used to make different foods, such as vinegar, cheeses, and sauerkraut.

• Bacteria also inhabit your intestines and produce vitamins and enzymes that help digest food.

Food and medicinesFood and medicines

• Streptomycin, erythromycin, bacitracin, and neomycin are some of these antibiotics.

• In addition to food, some bacteria produce important antibiotics that destroy other types of bacteria.

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Bacteria cause diseaseBacteria cause disease

• Bacteria also cause many human diseases.

• Bacteria cause diseases in plants and animals, causing crops and livestock losses that impact humans indirectly.

• Disease-causing bacteria can enter human bodies through openings, such as the mouth.

Bacteria cause diseaseBacteria cause disease

• The growth of the bacteria can interfere with the normal function of body tissue, or it can release a toxin that directly attacks the host.

• Bacterial diseases harm people in two ways.

Bacteria cause diseaseBacteria cause disease

Diseases Caused by Bacteria

Disease Transmission Symptoms Treatment

Strep throat

(Streptococcus)

Inhale or

ingest throughmouth

Fever, sore throat,

swollen neck glands

Antibiotic

Tuberculosis Inhale Fatigue, fever, night

sweats, cough, weight loss, chest pain

Antibiotic

Tetanus Puncture

wound

Stiff jaw, muscle

spasms, paralysisOpen and clean wound,

antibiotic; give antitoxin

Lyme disease Bite of

infected tick

Rash at site of bite,

chills, body aches,joint swelling

Antibiotic

Dentalcavities (caries)

Bacteria

in mouth

Destruction of tooth

enamel, toothache

Remove and fill the

destroyed area of tooth

Diptheria Inhale or

close contact

Sore throat, fever,

heart or breathing

failure

Vaccination to

prevent, antibiotics

Bacteria cause diseaseBacteria cause disease

• In the last 100 years, human life expectancy has increased to about 75 years.

• In the past, bacterial illnesses had a greater effect on human populations than they do now.

Bacteria cause diseaseBacteria cause disease

• This increase is due to many factors, including better public health systems, improved water and sewage treatment, better nutrition, and better medical care.

• These improvements, along with antibiotics, have reduced the death rates from bacterial diseases to low levels.

Which of the following best describes archaebacteria?

Question 1

D. parasitic heterotrophs

C. chemosynthetic autotrophs

B. photosynthetic autotrophs

A. anaerobic autotrophs

The answer is A.

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What part of a bacterial cell is most affected by penicillin?

Question 2

D. cell wall

C. flagellum

B. plasmid

A. pilus

The answer is D, cell wall.

Cell Wall

Which of the following is not a way to identify bacteria?

Question 3

D. lack of a plasma membrane

C. characteristic growth patterns

B. shape

A. the way in which their cell walls

reflect Gram stain

The answer is D.

Given their rapid reproductive rates, why aren’t there more bacteria than there actually are?

Question 4

Answer

Bacteria don’t always have ideal growing conditions. They run out of nutrients and water, they poison themselves with their own wastes, and predators eat them.

What is a pilus used for in a bacterium?

Question 5 A pilus helps a bacterium stick to a surface. It is also a bridge through or on which two bacteria can exchange DNA.

Capsule Cell Wall

Chromosome

Flagellum

PlasmidPilus

Plasma membrane

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• Viruses are nonliving particles that have a nucleic acid core and a protein-containing capsid.

Viruses

• To replicate, a virus must first recognize a host cell, then attach to it, and finally enter the host cell and take over its metabolism.

• During a lytic cycle, a virus replicates and kills the host cell. In a lysogenic cycle, a virus’s DNA is integrated into a chromosome of the host cell, but the host cell does not die.

Viruses

• Retroviruses contain RNA. Reverse transcriptase is an enzyme that helps convert viral RNA to DNA, which is then integrated into the host cell’s chromosome.

• Prions and viroids are virus-like particles. Prions are composed of only a protein, while a viroid is a singular strand of RNA.

Viruses

• Viruses probably originated from their host cells.

• There are two kingdoms of prokaryotes: archaebacteria and eubacteria. Archaebacteria inhabit extreme environments. Eubacteria live almost everywhere else. They probably arose separately from a common ancestor billions of years ago.

Archaebacteria and Eubacteria

• Bacteria are varied. Some are heterotrophs, some are photosynthetic autotrophs, and others are chemosynthetic autotrophs. Bacteria can be obligate aerobes, obligate anaerobes, or both aerobic and anaerobic.

Archaebacteria and Eubacteria Archaebacteria and Eubacteria

• Bacteria usually reproduce by binary fission. Some have a type of sexual reproduction called conjugation. Some bacteria form endospores that enable them to survive when conditions are unfavorable.

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Question 1

With lysogenic viruses, what two phases of the lytic cycle are replaced by the lysogenic cycle?

D. attachment and entry

C. assembly and lysis and release

B. replication and assemble

A. entry and replication

The answer is D.

LYSOGENIC CYCLE

LYTIC CYCLE

A. Attachment and Entry

Question 2

Explain why you can be infected with a virus but may have no symptoms of disease for years after the initial infection.

Answer

The virus enters a lysogenic phase remaining inactive but replicating along with the host cell’s chromosomes. Eventually, the virus enters a lytic phase where it destroys its host cells and causes symptoms of disease.

Question 3What is the difference between lysis and exocytosis with respect to host cells that contain viruses?

AnswerLysis, the bursting of the host cell, is caused when viruses break out of it. In exocytosis, the virus is enclosed in a vacuole that then fuses with the host cell’s plasma membrane. The virus is then released to the outside.

Question 4

What is the importance of reverse transcriptase to a retrovirus?

Answer

The enzyme reverse transcriptase allows the retrovirus to make DNA from its RNA so the DNA may attach to the chromosomes of the host cell and divide with the host cell.

Question 5

Particles that are composed of proteins but have no nucleic acid to carry genetic information are _______.

D. retroviruses

C. viroids

B. prions

A. proviruses

The answer is B.

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During ______, a bacterium transfers all or part of its chromosome to another bacterium.

D. chemosynthesis

C. conjugation

B. attachment

A. binary fission

The answer is C.

Question 6

What causes botulism?

Answer

Endospores of C. botulinum bacteria get into an anaerobic environment like improperly canned food, germinate, and produce a toxin as they grow. This toxin is then ingested by humans and causes poisoning called botulism.

Question 7

What causes anthrax?

Question 8 Endospores of B. anthracis bacteria produce endospores that can become airborne, and if inhaled in large amounts, can germinate in a person’s lungs causing a deadly infection that damages lung tissue and the circulatory system.

Question 9

Describe the process in which bacteria make nitrogen in the air accessible for use by plants.

Several species of bacteria have enzymes that convert nitrogen gas into ammonia. Other bacteria then convert the ammonia into nitrite and nitrate that plants can use.

Answer

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Question 10

What are the two ways in which bacterial diseases harm people?

Answer

The growth of the bacteria can interfere with the normal function of body tissue, or the bacteria can release a toxin that directly attacks the host.

Photo CreditsPhoto Credits

• Scott Ransom

• Centers for Disease Control, Atlanta, GA.

• Carolina Biological Supply Company

• USDA

• Lappa/Marquart

Photo CreditsPhoto Credits

• Diamar

• NOAA

• Wards Natural Science Est.

• Platinum

• PhotoDisc

• Alton Biggs

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