Turning TypeOne to The Plan for a World without T1D
Dec 23, 2015
Delivery of Continuous Therapeutic Improvements
Side-EffectsComplicationsPatient Burden
Glycemic ControlSafety
Normal PhysiologyRestored
Easier, Safer, Less Worry, Better Life
Therapies Cure
Artificial Pancreas
A series of systems that will automate insulin dosing and additional hormone delivery
Artificial Pancreas Artificial PancreasSmart Insulin
A series of systems that will automate insulin dosing and additional hormone delivery
Single dose of insulin that delivers insulin only where and
when needed
Artificial Pancreas Smart Insulin
Single dose of insulin that delivers insulin only where and
when needed
Smart InsulinEncapsulation
Implantable, beta cell replacement therapies restoring insulin
independence without the need for intensive immune suppression
Artificial Pancreas Smart Insulin EncapsulationEncapsulation
Implantable, beta cell replacement therapies restoring insulin
independence without the need for intensive immune suppression
Prevention
Slow or stop the progression of T1D before insulin dependence and
ultimately eliminate the possibility of ever developing T1D
Artificial Pancreas Smart Insulin Encapsulation
Prevention
Prevention
Slow or stop the progression of T1D before insulin dependence and
ultimately eliminate the possibility of ever developing T1D
Restoration
Beta cell growth protected from immune attack restoring insulin
independence without immune suppression
Restoration
Smart Insulin Encapsulation
Prevention
Artificial Pancreas
Beta cell growth protected from immune attack restoring insulin
independence without immune suppression
Restoration
Continuous Therapeutic Improvements N
ear T
erm
Mid
Ter
mLo
ng T
erm
ComplicationsDiabetic Eye DiseasePredictive Diagnostics
Artificial PancreasLow Glucose SuspendTreat-to-Range
Artificial PancreasTreat-to-TargetMultihormone
EncapsulationImplantable Islets
Smart InsulinControl
PreventionSecondary Prevention
PreventionPrimary: Vaccine
ComplicationsComprehensivePrevention Therapy
RestorationNew Beta Cell GrowthProtected from Immune Attack
Capabilities Across All Stages of the Pipeline
$500 Million Research PortfolioBroad and Diverse PortfolioResearch and Development ExpertiseVolunteer EngagementInternational ReachPartnerships