Under the auspices of the Medical Section of the Hungarian Academy of Sciences Scientific Program www.esptcongress.eu ESPT 2015 Third Conference Integration of Pharmacogenomics in clinical decision support October 7-8-9, 2015 Hungarian Academy of Sciences Budapest, Hungary
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Under the auspices of the Medical Section of the Hungarian Academy of Sciences
Scientific Programwww.esptcongress.eu
ESPT 2015Third ConferenceIntegration of Pharmacogenomics in clinical decision supportOctober 7-8-9, 2015Hungarian Academy of SciencesBudapest, Hungary
Committees
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Institute
Congress VenueHungarian Academy of Sciences Budapest 1051 Budapest, Széchenyi István sqr. 9Tel. :[email protected]
Contact Organization
Com&Co Events Benjamin Richier: [email protected] Tel. : 33 (0)4 91 09 70 53
Hungarian Academy of Sciences BudapestGyorgy Németh: [email protected] Molnar: [email protected]
• Ansari Marc, Geneva, CH
• Berecz Roland, Debrecen, HU
• Božina Nada, Zagreb, HR
• Cascorbi Ingolf, Kiel, DE
• Dumic Jerka, Zagreb, HR
• Ferrari Maurizio, Milan, IT
• Hubacek Jaroslav, Prague, CZ
• Jordan Bruce, Rotkreuz, CH
• Kovacs Gabor L., Pecs, HU
• Llerena Adrian, Badajoz, ES
• Manolopoulos Vangelis G., Alexandroupolis, GR
• Marc Janja, Ljubljana, SI
• Meyer Urs A., Basel, CH
• Molnár Mária Judit, Budapest, HU
• Németh György, Budapest, HU • Oellerich Michael, Göttingen, DE
• Pallaud Céline, Basel, CH
• Paulmichl Markus, Salzburg, AT
• Semiz Sabina, Sarajovo, BIH
• Siest Gerard, Nancy, FR
• Simmaco Maurizio, Roma, IT
• Sperlagh Beata, Budapest, HU
• Stankovic Sanja, Belgrade, SRB
• Van Schaik Ron H.N., Rotterdam, NL
• Visvikis-Siest Sophie, Nancy, FR
> Com&Co Events, Marseille, FR:
• Benjamin Richier
> INSERM Team and ESPT Office, Nancy, FR:
• Siest Gérard • Visvikis-Siest Sophie • Hiegel Brigitte • Durlin Anne • Ndiaye Ndeye Coumba • Stathopoulou Maria • Petrelis Alexandros • Aldasoro Arguinano Alex-Ander • Masson Christine • Chatelin Jérôme • Xie Ting • Ulmer Patricia
• Németh György, Budapest, HU
• Molnár Maria Judit, Budapest, HU
• Kovacs Gabor L., Pecs, HU
> Chair: • Maurizio Simmaco, Italy
> Members: • Stankovic Sanja, Serbia • Peiró Ana, Spain
• Ndeye Coumba Ndiaye, France
• Szalai Csaba, Hungary
SCIENTIFIC COMMITTEE ORGANIZATION COMMITTEE LOCAL ORGANIZATION
POSTER COMMITTEE
Tuesday 6 OctoberKEPES TEREM ROOM
13:30-20:00 ESPT Board meetingFollowed by a dinner
Wednesday 7 OctoberFELOLVASÓTEREM ROOM13:15-15:15Committee Pediatric individualised treatment in oncology and hematology> Janja Marc
KEPES TEREM ROOM
14:00-15:00Committee on pharmacogenomics information for generic drugs > Vangelis Manolopoulos
15:30-16:30Division Education and Course > Vangelis Manolopoulos /
Janja Marc
Thursday 8 OctoberFELOLVASÓTEREM ROOM08:00-09:00ESPT Corporate Members
KEPES TEREM ROOM09:30-10:30DMPT Editorial board
14:15-15:15Committee Drug Transporters > Ingolf Cascorbi
Friday 9 OctoberKEPES TEREM ROOM09:00-10:00Division Scientific and Clinical Implementation > Ron van Schaik / Janja Marc
10:00-12:00Joint EFLM / ESPT Working Group Meeting
DISZTEREM13:00-14:00ESPT General Assembly • Ordinary• Extraordinary
KEPES TEREM ROOM17:00-18:30VEGF Consortium Second meeting
Specific meetings planned in Budapest
08:00-09:00 Registration
09:00-10:00 OPENING CEREMONY DÍSZTEREM ROOM Masters of ceremony: > Mária Judit Molnár, Budapest, Hungary and Ron HN Van Schaik, Rotterdam, The Netherlands> György Németh, Budapest, President of HSPM (Hungarian Society of Personalised Medicine) > Csilla Pozsgay, General Director of Hungarian FDA (National Institute of Pharmacy and Nutrition)> Ágoston Szél, Rector of the Semmelweis University, Budapest, Hungary The Presidents of: EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) > Mauro Panteghini, Milano, Italy representated by Eva Ajzner, President of the Hungarian Society of Laboratory Medicine EPHAR (The Federation of European Pharmacological Societies) > Thomas Griesbacher, Vienna, Austria IFCC (International Federation of Clinical Chemistry and Laboratory Medicine) > Maurizio Ferrari, Milano, ItalyIUPHAR (International Union of Basic and Clinical Pharmacology) > Guilherme Suarez-Kurtz, Rio de Janeiro, BrazilESPT (European Society of Pharmacogenomics and Personalised Therapy. A Scientific Society for Individualised Medicine) > Gérard Siest, Nancy, France
10:00-11:00 OPENING LECTURES DÍSZTEREM ROOM Chairs: Urs A. Meyer, Basel, Switzerland / Magnus Ingelman-Sundberg, Stockholm, Sweden10:00-10:30 > Dan Roden, Nashville, USA - Opportunities and challenges in implementing pharmacogenomics and personalized medicine10:30-11:00 > Michael Hayden, Tel Aviv, Israel - Personalized medicine in neurological disorders11:00-11:15 Break
11:15-13:15 USE OF OMICS DATA FOR PERSONALIZED MEDICINE - ORGANIZED IN COLLABORATION WITH EUSPM DÍSZTEREM ROOM Chairs: György Németh, Budapest, Hungary / Guilherme Suarez-Kurtz, Rio de Janeiro, Brazil11:15-11:40 > György Németh, Budapest, Hungary - New challenges of the decade: the value of personalized and translational medicine11:40-12:05 > Maurizio Ferrari, Milano, Italy - Omics: from bench to benside 12:05-12:30 > Markus Paulmichl, Salzburg, Austria - Pharmacogenomics implementation – What are the Pitfalls?12:30-12:55 > Michael Neumaier, Heidelberg, Germany - The OMICS dimension in the age of molecular cancer diagnostics12:55-13:15 > Candan Hizel, Izmir, Turkey - Merging pharmacogenomic and phenomic data for patient drug metabolism efficacy
by help decision making system13:15-14:15 Lunch Break - Posters’ Visit
14:15-15:15 WORKSHOP 1 - THERMO FISHER SCIENTIFIC FELOLVASÓTEREM ROOM New developments for your pharmacogenomics research Chairs: Peter Jacobs, Gent, Belgium / Charity Nofziger, Salzburg, Austria14:15-14:35 > Le Ferrier, San Francisco, USA - Overcoming PCR Inhibitors to achieve rapid, accurate results in a high throughput
pharmacogenomics sample-to-answer solution14:35-14:55 > Dominique Dewolf, Saint-Aubin, France - CYP2D6 allele specific copy number analysis using TaqMan®
SNP genotyping assays and digital PCR14:55-15:15 > Dominique Dewolf, Saint-Aubin, France - Development of a pharmacogenomics research panel for the detection
of 137 known variants using a next generation sequencing assay15:15-15:30 Break
15:30-17:45 INTERINDIVIDUAL DÍSZTEREM ROOM DIFFERENCES OF DRUG TRANSPORTER FUNCTION
Chairs: Ingolf Cascorbi, Kiel, Germany / Christoph Funk, Basel Switzerland
15:30-15:55 > Christoph Funk, Basel, Switzerland - Role of drug transporters in early clinical development
15:55-16:20 > Ingolf Cascorbi, Kiel, Germany - Genetics and epigenetics of efflux transporters
16:20-16:45 > Toshihisa Ishikawa,Yokohama, Japan - Pharmacogenomics and Function of Human ATP-binding Cassette Transporter ABCG2
16:45-17:00 > Hanan Osman-Ponchet, Sophia-Antipolis, France - Characterization and regulation of the expression of drug transporters in human skin
17:00-17:15 > Nada Božina, Zagreb, Croatia - ABCG2 polymorphism as a risk factor for developing adverse drug reactions in patients taking atorvastatin: a case-control study
17:15-17:30 > Sabina Semiz, Sarajevo, Bosnia and Herzegovina - Pharmacogenomic Variations and Metformin Response
17:30-17:45 > Anna Klukovits, Solvo Biotechnology, Budaors, Hungary - Interaction of reference P-glycoprotein inhibitors with organic cation transporter families MATE and OCTN
17:45-18:30 GENERAL DISCUSSION WITH POSTER PRESENTERS ON DRUG TRANSPORTERS
15:30-17:00 WORKSHOP 2 - TEVA FELOLVASÓTEREM ROOM Repositioning old drugs for new indications
by use of personalised and genomics approaches Chairs: Daphna Laifenfeld, Tel Aviv, Israel /
Markus Paulmichl, Salzburg, Austria 15:30-15:45 > Daphna Laifenfeld, Tel Aviv, Israel - Introduction15:45-16:10 > P. Craig Webb, Palo Alto, USA - Drug repositioning
in the era of personalised medicine16:10-16:35 > G. Peolmans, Nijmegen, The Netherlands - Identifying
drug targets and (repurposed) disease-modifying compounds through building molecular landscapes for complex genetic disorders
16:35-17:00 > Markus Paulmichl, Salzburg, Austria - The regulator point of view
17:00-18:30 SELECTED TOPICS Chairs: Janja Marc, Ljubljana, Slovenia /
Filippo Drago, Catania, Italy17:15-17:35 > Janja Marc, Ljubljana, Slovenia - Epigenetics
in bone: microRNA profile in osteoblasts is affected by estrogen treatment
17:35-17:50 > Meliha Koldemir Gunduz, Istanbul, Turkey - The effects of glipizide on adipogenesis related gene expressions by using impedance-cell based label free technology in mature adipocytes
17:50-18:05 > Agnes F. Semsei, Budapest, Hungary - Anthracycline cardiotoxicity in childhood acute lymphoblastic leukemia
18:05-18:30 > Discussion
18:30-20:00 GET TOGETHER - Welcome Cocktail and Posters’ Visit by the Poster Committee
08:30-10:30 PERSONALIZED IMMUNOSUPPRESSION DÍSZTEREM ROOM Chairs: Michael Oellerich, Goettingen, Germany / András Falus, Budapest, Hungary08:30-08:55 > András Falus, Budapest, Hungary - Immunogenomics: toward the future trend of “intelligent” vaccines08:55-09:20 > Pierre Marquet, Limoges, France - Pharmacogenetics of mTOR inhibitors09:20-09:45 > Michael Oellerich, Goettingen, Germany - Biomarkers for personalized immunosuppression09:45-10:10 > Matthew Albert, Paris, France - Immunotest for personalized medicine10:10-10:30 > Samer Khaled, Duarte, USA - The influence of drug absorption, distribution, metabolism and excretion (ADME) genomic variants
on tacrolimus and sirolimus blood levels in the setting of Graft Versus Host Disease (GVHD) prophylaxis10:30-11:00 Break
11:00-13:00 PHARMACOGENOMICS OF CARDIOVASCULAR AND ANTIDIABETIC DRUGS DÍSZTEREM ROOM Chairs: Gábor Kovács, Pécs, Hungary / Jaroslav Hubacek, Prague, Czech Republic11:00-11:25 > Jaroslav Hubacek, Prague, Czech Republic - Pharmacogenetics of statin treatment efficacy and statin adverse effects11:25-11:50 > Ivan Tkac, Bratislavia, Slovakia - Pharmacogenomics of oral antidiabetic drugs11:50-12:15 > György Pfliegler, Debrecen, Hungary - Personalized approach to patients with bleeding or thrombotic disorders12:15-12:40 > Sanja Stankovic, Belgrade, Serbia - Gene polymorphisms, platelet reactivity, and the RISK-PCI Score in predicting MACE
in STEMI patients: cost-effectiveness analysis12:40-13:00 > Georgia Ragia, Alexandroupolis, Greece - Factors that affect acenocoumarol dosing requirements: analysis
of the Greek population recruited in European pharmacogenetics of anticoagulant therapy (EU-PACT) trial13:00-14:00 Lunch Break - Posters’ Visit
14:00-16:00 WORKSHOP 3 FELOLVASÓTEREM ROOM Pharmacogenomics data treatment and software for interpretation Chairs: Houda Hachad, Bellevue, WA, USA / Gérard Siest, Nancy, France14:00-14:10 > Houda Hachad, CSO., Translational Software, WA, USA - Introduction14:10-14:30 > Don Rule, CEO. Translational Software Bellevue WA, USA - Democratizing access to pharmacogenetics14:30-14:45 > Ana Sabater-Sales, Eugonomic, Barcelona, Spain - G-NOMIC: The tool for practical application of pharmacogenetics14:45-15:00 > Oskari Huiskala, Abomics Oy, Finland - The use of advanced information technology in implementing pharmacogenomics
into clinical practice15:00-15:15 > Herna Munoz-Galeano, HMG Systems Engineering GmbH, Fürth, Germany - Therapeutic decision support based on genomic
disposition for patients receiving multiple drugs15:15-15:30 > Ales Smokvina, Marand, Slovenia - OpenEHR as interoperable platform for open health data15:30-15:45 > Discussion15:45-16:00 Break
20:00 AWARD DINNER
16:00-17:30 THE PHARMACOGENOMICS DÍSZTEREM ROOM OF ASTHMA TREATMENT
Chairs: Vangelis Manolopoulos, Alexandroupolis, Greece / Sabina Semiz, Sarajevo, Bosnia and Herzegovina
16:00-16:25 > Anke-Hilse Maitland van der Zee, Utrecht, The Netherlands - Pharmacogenomics of pediatric asthma treatment
16:25-16:50 > Somnath Mukhopadhyay, Brighton, United Kingdom - Pharmacogenetic clinical trials in asthma treatment
16:50-17:15 > Ildikó Horváth, Budapest, Hungary - TBC17:15-17:30 > Vangelis Manolopoulos, Alexandroupolis, Greece -
Endothelial Nitric Oxide synthase G894T gene polymorphism is associated with response to combination of inhaled corticosteroids with long lasting ß2-agonists in Greek asthmatic children
16:00-17:30 GENOMICS OF VEGF KÉPES TEREM ROOM AND DISEASES PREDICTION
Chairs: Sophie Visvikis-Siest, Nancy, France / John Lamont, Co Antrim, United Kingdom
16:00-16:20 > Sophie Visvikis-Siest, Nancy, France - The VEGF clinical implementation pathway
16:20-16:40 > Marc Rancier, Nancy, France - VEGF in clinical endocrinology
16:40-17:00 > Kevin Lagan, Co Antrim, United Kingdom - Specificity of VEGF bio markers
17:00-17:20 > Behrooz Alizadeh, Groningen, The Netherlands VEGF and stroke
17:20-17:30 > Discussion
Wednesday 7 October 2015 Thursday 8 October 2015 Friday 9 October 201508:30-10:00 PHARMACOGENOMICS IN PAIN TREATMENT DÍSZTEREM ROOM Chairs: Adrian Llerena, Badajoz, Spain / Beáta Sperlágh, Budapest, Hungary 08:30-08:35 > Adrian Llerena, Badajoz, Spain - Introduction08:35-08:55 > György Bagdy, Budapest, Hungary - Genomics of pain and comorbid disorders08:55-09:10 > Mariela Guevara, Cuba - Pharmacological basis of treatment of pain with natural product09:10-09:25 > Ana Peiró, Alicante, Spain - Pharmacogenectics and individualizing drug treatment in chronic pain09:25-09:45 > Alain Eschalier, Clermont-Ferrand, France - “Analgesic effect of paracetamol: a new insight”
or “Paracetamol: a centrally-acting analgesic”09:45-10:00 > Jérôme Busserolles, Clermont-Ferrand, France - Epigenetic regulations and neuropathic pains10:00-10:30 Break
10:30-12:30 PERSONALIZING TREATMENT STRATEGIES IN ONCO-HEMATOLOGY DÍSZTEREM ROOM Chairs: Marc Ansari, Geneva, Switzerland / József Tímár, Budapest, Hungary10:30-10:40 > Marc Ansari, Geneva, Switzerland - Introduction10:40-11:05 > József Tímár, Budapest, Hungary - “Precision oncology” based on the genetic information of the primary tumor?11:05-11:30 > Céline Pallaud, Basel, Switzerland - Tyrosine kinase inhibitor in oncology11:30-12:05 > Joseph Ciccolini, Marseille, France - Pharmacogenetics of myelodysplastic syndromes: CDA status as a predictive marker
of clinical outcome in patients undergoing cytarabine and azacytidine therapy12:05-12:30 > Ettore Biagi, Milano, Italy - CAR therapy in hematological malignancies: facts and future challenges12:30-14:00 Lunch Break and ESPT General Assembly
14:00-18:00 CLINICAL IMPLEMENTATION OF PHARMACOGENOMICS DATA DÍSZTEREM ROOM14:00-15:30 Toward practical application of Big Data and Digital Health for personalised medicine: revolution is now Chairs: Patrice Denefle, Paris, France / Thomas Griesbacher, Graz, Austria14:00-14-15 > Patrice Denèfle, Institut Roche, France - Introduction14:15-14-40 > Uwe Diegel, Paris, France - The impact of digital health as a tool for clinical research14:40-15-05 > Scott Kahn, Illumina, USA - The role of Big Data in supporting clinician researchers for precision medicine15:05-15-30 > Andreas Posch, Siemens Healthcare, Erlangen, Germany - Patient-specific disease modeling for therapy decision support15:30-18:00 Specific Workshop and round table Chairs: Adrian Llerena, Badajoz, Spain / Ron van Schaik, Rotterdam, The Netherlands / Mária Judit Molnár, Budapest, Hungary With the participation of general practitioners, young clinicians, the ESPT board members and specialised colleagues,
the speakers of the big data session and specialised software translational companies Introduction15:30-15-45 > Ron van Schaik, Rotterdam, The Netherlands - The EuPIC initiative – Pre-emptive pharmacogenomics Targeted Cancer therapy15:45-16-05 > Paolo Marchetti, Roma, Italy - TBC 16:05-16-25 > Gérard Milano, Nice, France - Pharmacogenomics of DPD and clinical impact in cancer therapy16:25-16:40 > Discussion between clinicians and specialists Neurodegenerative diseases 16:40-17:00 > Mária Judit Molnár, Budapest, Hungary - Mitochondrial genomic variations and personalized treatment strategies17:00-17:20 > Magnus Ingelman-Sundberg, Stockholm, Sweden - Pharmacogenomics of Alzheimer and neurodegenerative diseases17:20-17:35 > Discussion between clinicians and specialists General discussion and Closing remarks17:35-18:00 > Adrian Llerena, Badajoz, Spain - Relevance of European drug regulation for clinical implementation
and all participants
08:00-09:00 Registration
09:00-10:00 OPENING CEREMONY DÍSZTEREM ROOM Masters of ceremony: > Mária Judit Molnár, Budapest, Hungary and Ron HN Van Schaik, Rotterdam, The Netherlands> György Németh, Budapest, President of HSPM (Hungarian Society of Personalised Medicine) > Csilla Pozsgay, General Director of Hungarian FDA (National Institute of Pharmacy and Nutrition)> Ágoston Szél, Rector of the Semmelweis University, Budapest, Hungary The Presidents of: EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) > Mauro Panteghini, Milano, Italy representated by Eva Ajzner, President of the Hungarian Society of Laboratory Medicine EPHAR (The Federation of European Pharmacological Societies) > Thomas Griesbacher, Vienna, Austria IFCC (International Federation of Clinical Chemistry and Laboratory Medicine) > Maurizio Ferrari, Milano, ItalyIUPHAR (International Union of Basic and Clinical Pharmacology) > Guilherme Suarez-Kurtz, Rio de Janeiro, BrazilESPT (European Society of Pharmacogenomics and Personalised Therapy. A Scientific Society for Individualised Medicine) > Gérard Siest, Nancy, France
10:00-11:00 OPENING LECTURES DÍSZTEREM ROOM Chairs: Urs A. Meyer, Basel, Switzerland / Magnus Ingelman-Sundberg, Stockholm, Sweden10:00-10:30 > Dan Roden, Nashville, USA - Opportunities and challenges in implementing pharmacogenomics and personalized medicine10:30-11:00 > Michael Hayden, Tel Aviv, Israel - Personalized medicine in neurological disorders11:00-11:15 Break
11:15-13:15 USE OF OMICS DATA FOR PERSONALIZED MEDICINE - ORGANIZED IN COLLABORATION WITH EUSPM DÍSZTEREM ROOM Chairs: György Németh, Budapest, Hungary / Guilherme Suarez-Kurtz, Rio de Janeiro, Brazil11:15-11:40 > György Németh, Budapest, Hungary - New challenges of the decade: the value of personalized and translational medicine11:40-12:05 > Maurizio Ferrari, Milano, Italy - Omics: from bench to benside 12:05-12:30 > Markus Paulmichl, Salzburg, Austria - Pharmacogenomics implementation – What are the Pitfalls?12:30-12:55 > Michael Neumaier, Heidelberg, Germany - The OMICS dimension in the age of molecular cancer diagnostics12:55-13:15 > Candan Hizel, Izmir, Turkey - Merging pharmacogenomic and phenomic data for patient drug metabolism efficacy
by help decision making system13:15-14:15 Lunch Break - Posters’ Visit
14:15-15:15 WORKSHOP 1 - THERMO FISHER SCIENTIFIC FELOLVASÓTEREM ROOM New developments for your pharmacogenomics research Chairs: Peter Jacobs, Gent, Belgium / Charity Nofziger, Salzburg, Austria14:15-14:35 > Le Ferrier, San Francisco, USA - Overcoming PCR Inhibitors to achieve rapid, accurate results in a high throughput
pharmacogenomics sample-to-answer solution14:35-14:55 > Dominique Dewolf, Saint-Aubin, France - CYP2D6 allele specific copy number analysis using TaqMan®
SNP genotyping assays and digital PCR14:55-15:15 > Dominique Dewolf, Saint-Aubin, France - Development of a pharmacogenomics research panel for the detection
of 137 known variants using a next generation sequencing assay15:15-15:30 Break
15:30-17:45 INTERINDIVIDUAL DÍSZTEREM ROOM DIFFERENCES OF DRUG TRANSPORTER FUNCTION
Chairs: Ingolf Cascorbi, Kiel, Germany / Christoph Funk, Basel Switzerland
15:30-15:55 > Christoph Funk, Basel, Switzerland - Role of drug transporters in early clinical development
15:55-16:20 > Ingolf Cascorbi, Kiel, Germany - Genetics and epigenetics of efflux transporters
16:20-16:45 > Toshihisa Ishikawa,Yokohama, Japan - Pharmacogenomics and Function of Human ATP-binding Cassette Transporter ABCG2
16:45-17:00 > Hanan Osman-Ponchet, Sophia-Antipolis, France - Characterization and regulation of the expression of drug transporters in human skin
17:00-17:15 > Nada Božina, Zagreb, Croatia - ABCG2 polymorphism as a risk factor for developing adverse drug reactions in patients taking atorvastatin: a case-control study
17:15-17:30 > Sabina Semiz, Sarajevo, Bosnia and Herzegovina - Pharmacogenomic Variations and Metformin Response
17:30-17:45 > Anna Klukovits, Solvo Biotechnology, Budaors, Hungary - Interaction of reference P-glycoprotein inhibitors with organic cation transporter families MATE and OCTN
17:45-18:30 GENERAL DISCUSSION WITH POSTER PRESENTERS ON DRUG TRANSPORTERS
15:30-17:00 WORKSHOP 2 - TEVA FELOLVASÓTEREM ROOM Repositioning old drugs for new indications
by use of personalised and genomics approaches Chairs: Daphna Laifenfeld, Tel Aviv, Israel /
Markus Paulmichl, Salzburg, Austria 15:30-15:45 > Daphna Laifenfeld, Tel Aviv, Israel - Introduction15:45-16:10 > P. Craig Webb, Palo Alto, USA - Drug repositioning
in the era of personalised medicine16:10-16:35 > G. Peolmans, Nijmegen, The Netherlands - Identifying
drug targets and (repurposed) disease-modifying compounds through building molecular landscapes for complex genetic disorders
16:35-17:00 > Markus Paulmichl, Salzburg, Austria - The regulator point of view
17:00-18:30 SELECTED TOPICS Chairs: Janja Marc, Ljubljana, Slovenia /
Filippo Drago, Catania, Italy17:15-17:35 > Janja Marc, Ljubljana, Slovenia - Epigenetics
in bone: microRNA profile in osteoblasts is affected by estrogen treatment
17:35-17:50 > Meliha Koldemir Gunduz, Istanbul, Turkey - The effects of glipizide on adipogenesis related gene expressions by using impedance-cell based label free technology in mature adipocytes
17:50-18:05 > Agnes F. Semsei, Budapest, Hungary - Anthracycline cardiotoxicity in childhood acute lymphoblastic leukemia
18:05-18:30 > Discussion
18:30-20:00 GET TOGETHER - Welcome Cocktail and Posters’ Visit by the Poster Committee
08:30-10:30 PERSONALIZED IMMUNOSUPPRESSION DÍSZTEREM ROOM Chairs: Michael Oellerich, Goettingen, Germany / András Falus, Budapest, Hungary08:30-08:55 > András Falus, Budapest, Hungary - Immunogenomics: toward the future trend of “intelligent” vaccines08:55-09:20 > Pierre Marquet, Limoges, France - Pharmacogenetics of mTOR inhibitors09:20-09:45 > Michael Oellerich, Goettingen, Germany - Biomarkers for personalized immunosuppression09:45-10:10 > Matthew Albert, Paris, France - Immunotest for personalized medicine10:10-10:30 > Samer Khaled, Duarte, USA - The influence of drug absorption, distribution, metabolism and excretion (ADME) genomic variants
on tacrolimus and sirolimus blood levels in the setting of Graft Versus Host Disease (GVHD) prophylaxis10:30-11:00 Break
11:00-13:00 PHARMACOGENOMICS OF CARDIOVASCULAR AND ANTIDIABETIC DRUGS DÍSZTEREM ROOM Chairs: Gábor Kovács, Pécs, Hungary / Jaroslav Hubacek, Prague, Czech Republic11:00-11:25 > Jaroslav Hubacek, Prague, Czech Republic - Pharmacogenetics of statin treatment efficacy and statin adverse effects11:25-11:50 > Ivan Tkac, Bratislavia, Slovakia - Pharmacogenomics of oral antidiabetic drugs11:50-12:15 > György Pfliegler, Debrecen, Hungary - Personalized approach to patients with bleeding or thrombotic disorders12:15-12:40 > Sanja Stankovic, Belgrade, Serbia - Gene polymorphisms, platelet reactivity, and the RISK-PCI Score in predicting MACE
in STEMI patients: cost-effectiveness analysis12:40-13:00 > Georgia Ragia, Alexandroupolis, Greece - Factors that affect acenocoumarol dosing requirements: analysis
of the Greek population recruited in European pharmacogenetics of anticoagulant therapy (EU-PACT) trial13:00-14:00 Lunch Break - Posters’ Visit
14:00-16:00 WORKSHOP 3 FELOLVASÓTEREM ROOM Pharmacogenomics data treatment and software for interpretation Chairs: Houda Hachad, Bellevue, WA, USA / Gérard Siest, Nancy, France14:00-14:10 > Houda Hachad, CSO., Translational Software, WA, USA - Introduction14:10-14:30 > Don Rule, CEO. Translational Software Bellevue WA, USA - Democratizing access to pharmacogenetics14:30-14:45 > Ana Sabater-Sales, Eugonomic, Barcelona, Spain - G-NOMIC: The tool for practical application of pharmacogenetics14:45-15:00 > Oskari Huiskala, Abomics Oy, Finland - The use of advanced information technology in implementing pharmacogenomics
into clinical practice15:00-15:15 > Herna Munoz-Galeano, HMG Systems Engineering GmbH, Fürth, Germany - Therapeutic decision support based on genomic
disposition for patients receiving multiple drugs15:15-15:30 > Ales Smokvina, Marand, Slovenia - OpenEHR as interoperable platform for open health data15:30-15:45 > Discussion15:45-16:00 Break
20:00 AWARD DINNER
16:00-17:30 THE PHARMACOGENOMICS DÍSZTEREM ROOM OF ASTHMA TREATMENT
Chairs: Vangelis Manolopoulos, Alexandroupolis, Greece / Sabina Semiz, Sarajevo, Bosnia and Herzegovina
16:00-16:25 > Anke-Hilse Maitland van der Zee, Utrecht, The Netherlands - Pharmacogenomics of pediatric asthma treatment
16:25-16:50 > Somnath Mukhopadhyay, Brighton, United Kingdom - Pharmacogenetic clinical trials in asthma treatment
16:50-17:15 > Ildikó Horváth, Budapest, Hungary - TBC17:15-17:30 > Vangelis Manolopoulos, Alexandroupolis, Greece -
Endothelial Nitric Oxide synthase G894T gene polymorphism is associated with response to combination of inhaled corticosteroids with long lasting ß2-agonists in Greek asthmatic children
16:00-17:30 GENOMICS OF VEGF KÉPES TEREM ROOM AND DISEASES PREDICTION
Chairs: Sophie Visvikis-Siest, Nancy, France / John Lamont, Co Antrim, United Kingdom
16:00-16:20 > Sophie Visvikis-Siest, Nancy, France - The VEGF clinical implementation pathway
16:20-16:40 > Marc Rancier, Nancy, France - VEGF in clinical endocrinology
16:40-17:00 > Kevin Lagan, Co Antrim, United Kingdom - Specificity of VEGF bio markers
17:00-17:20 > Behrooz Alizadeh, Groningen, The Netherlands VEGF and stroke
17:20-17:30 > Discussion
Wednesday 7 October 2015 Thursday 8 October 2015 Friday 9 October 201508:30-10:00 PHARMACOGENOMICS IN PAIN TREATMENT DÍSZTEREM ROOM Chairs: Adrian Llerena, Badajoz, Spain / Beáta Sperlágh, Budapest, Hungary 08:30-08:35 > Adrian Llerena, Badajoz, Spain - Introduction08:35-08:55 > György Bagdy, Budapest, Hungary - Genomics of pain and comorbid disorders08:55-09:10 > Mariela Guevara, Cuba - Pharmacological basis of treatment of pain with natural product09:10-09:25 > Ana Peiró, Alicante, Spain - Pharmacogenectics and individualizing drug treatment in chronic pain09:25-09:45 > Alain Eschalier, Clermont-Ferrand, France - “Analgesic effect of paracetamol: a new insight”
or “Paracetamol: a centrally-acting analgesic”09:45-10:00 > Jérôme Busserolles, Clermont-Ferrand, France - Epigenetic regulations and neuropathic pains10:00-10:30 Break
10:30-12:30 PERSONALIZING TREATMENT STRATEGIES IN ONCO-HEMATOLOGY DÍSZTEREM ROOM Chairs: Marc Ansari, Geneva, Switzerland / József Tímár, Budapest, Hungary10:30-10:40 > Marc Ansari, Geneva, Switzerland - Introduction10:40-11:05 > József Tímár, Budapest, Hungary - “Precision oncology” based on the genetic information of the primary tumor?11:05-11:30 > Céline Pallaud, Basel, Switzerland - Tyrosine kinase inhibitor in oncology11:30-12:05 > Joseph Ciccolini, Marseille, France - Pharmacogenetics of myelodysplastic syndromes: CDA status as a predictive marker
of clinical outcome in patients undergoing cytarabine and azacytidine therapy12:05-12:30 > Ettore Biagi, Milano, Italy - CAR therapy in hematological malignancies: facts and future challenges12:30-14:00 Lunch Break and ESPT General Assembly
14:00-18:00 CLINICAL IMPLEMENTATION OF PHARMACOGENOMICS DATA DÍSZTEREM ROOM14:00-15:30 Toward practical application of Big Data and Digital Health for personalised medicine: revolution is now Chairs: Patrice Denefle, Paris, France / Thomas Griesbacher, Graz, Austria14:00-14-15 > Patrice Denèfle, Institut Roche, France - Introduction14:15-14-40 > Uwe Diegel, Paris, France - The impact of digital health as a tool for clinical research14:40-15-05 > Scott Kahn, Illumina, USA - The role of Big Data in supporting clinician researchers for precision medicine15:05-15-30 > Andreas Posch, Siemens Healthcare, Erlangen, Germany - Patient-specific disease modeling for therapy decision support15:30-18:00 Specific Workshop and round table Chairs: Adrian Llerena, Badajoz, Spain / Ron van Schaik, Rotterdam, The Netherlands / Mária Judit Molnár, Budapest, Hungary With the participation of general practitioners, young clinicians, the ESPT board members and specialised colleagues,
the speakers of the big data session and specialised software translational companies Introduction15:30-15-45 > Ron van Schaik, Rotterdam, The Netherlands - The EuPIC initiative – Pre-emptive pharmacogenomics Targeted Cancer therapy15:45-16-05 > Paolo Marchetti, Roma, Italy - TBC 16:05-16-25 > Gérard Milano, Nice, France - Pharmacogenomics of DPD and clinical impact in cancer therapy16:25-16:40 > Discussion between clinicians and specialists Neurodegenerative diseases 16:40-17:00 > Mária Judit Molnár, Budapest, Hungary - Mitochondrial genomic variations and personalized treatment strategies17:00-17:20 > Magnus Ingelman-Sundberg, Stockholm, Sweden - Pharmacogenomics of Alzheimer and neurodegenerative diseases17:20-17:35 > Discussion between clinicians and specialists General discussion and Closing remarks17:35-18:00 > Adrian Llerena, Badajoz, Spain - Relevance of European drug regulation for clinical implementation
and all participants
08:00-09:00 Registration
09:00-10:00 OPENING CEREMONY DÍSZTEREM ROOM Masters of ceremony: > Mária Judit Molnár, Budapest, Hungary and Ron HN Van Schaik, Rotterdam, The Netherlands> György Németh, Budapest, President of HSPM (Hungarian Society of Personalised Medicine) > Csilla Pozsgay, General Director of Hungarian FDA (National Institute of Pharmacy and Nutrition)> Ágoston Szél, Rector of the Semmelweis University, Budapest, Hungary The Presidents of: EFLM (European Federation of Clinical Chemistry and Laboratory Medicine) > Mauro Panteghini, Milano, Italy representated by Eva Ajzner, President of the Hungarian Society of Laboratory Medicine EPHAR (The Federation of European Pharmacological Societies) > Thomas Griesbacher, Vienna, Austria IFCC (International Federation of Clinical Chemistry and Laboratory Medicine) > Maurizio Ferrari, Milano, ItalyIUPHAR (International Union of Basic and Clinical Pharmacology) > Guilherme Suarez-Kurtz, Rio de Janeiro, BrazilESPT (European Society of Pharmacogenomics and Personalised Therapy. A Scientific Society for Individualised Medicine) > Gérard Siest, Nancy, France
10:00-11:00 OPENING LECTURES DÍSZTEREM ROOM Chairs: Urs A. Meyer, Basel, Switzerland / Magnus Ingelman-Sundberg, Stockholm, Sweden10:00-10:30 > Dan Roden, Nashville, USA - Opportunities and challenges in implementing pharmacogenomics and personalized medicine10:30-11:00 > Michael Hayden, Tel Aviv, Israel - Personalized medicine in neurological disorders11:00-11:15 Break
11:15-13:15 USE OF OMICS DATA FOR PERSONALIZED MEDICINE - ORGANIZED IN COLLABORATION WITH EUSPM DÍSZTEREM ROOM Chairs: György Németh, Budapest, Hungary / Guilherme Suarez-Kurtz, Rio de Janeiro, Brazil11:15-11:40 > György Németh, Budapest, Hungary - New challenges of the decade: the value of personalized and translational medicine11:40-12:05 > Maurizio Ferrari, Milano, Italy - Omics: from bench to benside 12:05-12:30 > Markus Paulmichl, Salzburg, Austria - Pharmacogenomics implementation – What are the Pitfalls?12:30-12:55 > Michael Neumaier, Heidelberg, Germany - The OMICS dimension in the age of molecular cancer diagnostics12:55-13:15 > Candan Hizel, Izmir, Turkey - Merging pharmacogenomic and phenomic data for patient drug metabolism efficacy
by help decision making system13:15-14:15 Lunch Break - Posters’ Visit
14:15-15:15 WORKSHOP 1 - THERMO FISHER SCIENTIFIC FELOLVASÓTEREM ROOM New developments for your pharmacogenomics research Chairs: Peter Jacobs, Gent, Belgium / Charity Nofziger, Salzburg, Austria14:15-14:35 > Le Ferrier, San Francisco, USA - Overcoming PCR Inhibitors to achieve rapid, accurate results in a high throughput
pharmacogenomics sample-to-answer solution14:35-14:55 > Dominique Dewolf, Saint-Aubin, France - CYP2D6 allele specific copy number analysis using TaqMan®
SNP genotyping assays and digital PCR14:55-15:15 > Dominique Dewolf, Saint-Aubin, France - Development of a pharmacogenomics research panel for the detection
of 137 known variants using a next generation sequencing assay15:15-15:30 Break
15:30-17:45 INTERINDIVIDUAL DÍSZTEREM ROOM DIFFERENCES OF DRUG TRANSPORTER FUNCTION
Chairs: Ingolf Cascorbi, Kiel, Germany / Christoph Funk, Basel Switzerland
15:30-15:55 > Christoph Funk, Basel, Switzerland - Role of drug transporters in early clinical development
15:55-16:20 > Ingolf Cascorbi, Kiel, Germany - Genetics and epigenetics of efflux transporters
16:20-16:45 > Toshihisa Ishikawa,Yokohama, Japan - Pharmacogenomics and Function of Human ATP-binding Cassette Transporter ABCG2
16:45-17:00 > Hanan Osman-Ponchet, Sophia-Antipolis, France - Characterization and regulation of the expression of drug transporters in human skin
17:00-17:15 > Nada Božina, Zagreb, Croatia - ABCG2 polymorphism as a risk factor for developing adverse drug reactions in patients taking atorvastatin: a case-control study
17:15-17:30 > Sabina Semiz, Sarajevo, Bosnia and Herzegovina - Pharmacogenomic Variations and Metformin Response
17:30-17:45 > Anna Klukovits, Solvo Biotechnology, Budaors, Hungary - Interaction of reference P-glycoprotein inhibitors with organic cation transporter families MATE and OCTN
17:45-18:30 GENERAL DISCUSSION WITH POSTER PRESENTERS ON DRUG TRANSPORTERS
15:30-17:00 WORKSHOP 2 - TEVA FELOLVASÓTEREM ROOM Repositioning old drugs for new indications
by use of personalised and genomics approaches Chairs: Daphna Laifenfeld, Tel Aviv, Israel /
Markus Paulmichl, Salzburg, Austria 15:30-15:45 > Daphna Laifenfeld, Tel Aviv, Israel - Introduction15:45-16:10 > P. Craig Webb, Palo Alto, USA - Drug repositioning
in the era of personalised medicine16:10-16:35 > G. Peolmans, Nijmegen, The Netherlands - Identifying
drug targets and (repurposed) disease-modifying compounds through building molecular landscapes for complex genetic disorders
16:35-17:00 > Markus Paulmichl, Salzburg, Austria - The regulator point of view
17:00-18:30 SELECTED TOPICS Chairs: Janja Marc, Ljubljana, Slovenia /
Filippo Drago, Catania, Italy17:15-17:35 > Janja Marc, Ljubljana, Slovenia - Epigenetics
in bone: microRNA profile in osteoblasts is affected by estrogen treatment
17:35-17:50 > Meliha Koldemir Gunduz, Istanbul, Turkey - The effects of glipizide on adipogenesis related gene expressions by using impedance-cell based label free technology in mature adipocytes
17:50-18:05 > Agnes F. Semsei, Budapest, Hungary - Anthracycline cardiotoxicity in childhood acute lymphoblastic leukemia
18:05-18:30 > Discussion
18:30-20:00 GET TOGETHER - Welcome Cocktail and Posters’ Visit by the Poster Committee
08:30-10:30 PERSONALIZED IMMUNOSUPPRESSION DÍSZTEREM ROOM Chairs: Michael Oellerich, Goettingen, Germany / András Falus, Budapest, Hungary08:30-08:55 > András Falus, Budapest, Hungary - Immunogenomics: toward the future trend of “intelligent” vaccines08:55-09:20 > Pierre Marquet, Limoges, France - Pharmacogenetics of mTOR inhibitors09:20-09:45 > Michael Oellerich, Goettingen, Germany - Biomarkers for personalized immunosuppression09:45-10:10 > Matthew Albert, Paris, France - Immunotest for personalized medicine10:10-10:30 > Samer Khaled, Duarte, USA - The influence of drug absorption, distribution, metabolism and excretion (ADME) genomic variants
on tacrolimus and sirolimus blood levels in the setting of Graft Versus Host Disease (GVHD) prophylaxis10:30-11:00 Break
11:00-13:00 PHARMACOGENOMICS OF CARDIOVASCULAR AND ANTIDIABETIC DRUGS DÍSZTEREM ROOM Chairs: Gábor Kovács, Pécs, Hungary / Jaroslav Hubacek, Prague, Czech Republic11:00-11:25 > Jaroslav Hubacek, Prague, Czech Republic - Pharmacogenetics of statin treatment efficacy and statin adverse effects11:25-11:50 > Ivan Tkac, Bratislavia, Slovakia - Pharmacogenomics of oral antidiabetic drugs11:50-12:15 > György Pfliegler, Debrecen, Hungary - Personalized approach to patients with bleeding or thrombotic disorders12:15-12:40 > Sanja Stankovic, Belgrade, Serbia - Gene polymorphisms, platelet reactivity, and the RISK-PCI Score in predicting MACE
in STEMI patients: cost-effectiveness analysis12:40-13:00 > Georgia Ragia, Alexandroupolis, Greece - Factors that affect acenocoumarol dosing requirements: analysis
of the Greek population recruited in European pharmacogenetics of anticoagulant therapy (EU-PACT) trial13:00-14:00 Lunch Break - Posters’ Visit
14:00-16:00 WORKSHOP 3 FELOLVASÓTEREM ROOM Pharmacogenomics data treatment and software for interpretation Chairs: Houda Hachad, Bellevue, WA, USA / Gérard Siest, Nancy, France14:00-14:10 > Houda Hachad, CSO., Translational Software, WA, USA - Introduction14:10-14:30 > Don Rule, CEO. Translational Software Bellevue WA, USA - Democratizing access to pharmacogenetics14:30-14:45 > Ana Sabater-Sales, Eugonomic, Barcelona, Spain - G-NOMIC: The tool for practical application of pharmacogenetics14:45-15:00 > Oskari Huiskala, Abomics Oy, Finland - The use of advanced information technology in implementing pharmacogenomics
into clinical practice15:00-15:15 > Herna Munoz-Galeano, HMG Systems Engineering GmbH, Fürth, Germany - Therapeutic decision support based on genomic
disposition for patients receiving multiple drugs15:15-15:30 > Ales Smokvina, Marand, Slovenia - OpenEHR as interoperable platform for open health data15:30-15:45 > Discussion15:45-16:00 Break
20:00 AWARD DINNER
16:00-17:30 THE PHARMACOGENOMICS DÍSZTEREM ROOM OF ASTHMA TREATMENT
Chairs: Vangelis Manolopoulos, Alexandroupolis, Greece / Sabina Semiz, Sarajevo, Bosnia and Herzegovina
16:00-16:25 > Anke-Hilse Maitland van der Zee, Utrecht, The Netherlands - Pharmacogenomics of pediatric asthma treatment
16:25-16:50 > Somnath Mukhopadhyay, Brighton, United Kingdom - Pharmacogenetic clinical trials in asthma treatment
16:50-17:15 > Ildikó Horváth, Budapest, Hungary - TBC17:15-17:30 > Vangelis Manolopoulos, Alexandroupolis, Greece -
Endothelial Nitric Oxide synthase G894T gene polymorphism is associated with response to combination of inhaled corticosteroids with long lasting ß2-agonists in Greek asthmatic children
16:00-17:30 GENOMICS OF VEGF KÉPES TEREM ROOM AND DISEASES PREDICTION
Chairs: Sophie Visvikis-Siest, Nancy, France / John Lamont, Co Antrim, United Kingdom
16:00-16:20 > Sophie Visvikis-Siest, Nancy, France - The VEGF clinical implementation pathway
16:20-16:40 > Marc Rancier, Nancy, France - VEGF in clinical endocrinology
16:40-17:00 > Kevin Lagan, Co Antrim, United Kingdom - Specificity of VEGF bio markers
17:00-17:20 > Behrooz Alizadeh, Groningen, The Netherlands VEGF and stroke
17:20-17:30 > Discussion
Wednesday 7 October 2015 Thursday 8 October 2015 Friday 9 October 201508:30-10:00 PHARMACOGENOMICS IN PAIN TREATMENT DÍSZTEREM ROOM Chairs: Adrian Llerena, Badajoz, Spain / Beáta Sperlágh, Budapest, Hungary 08:30-08:35 > Adrian Llerena, Badajoz, Spain - Introduction08:35-08:55 > György Bagdy, Budapest, Hungary - Genomics of pain and comorbid disorders08:55-09:10 > Mariela Guevara, Cuba - Pharmacological basis of treatment of pain with natural product09:10-09:25 > Ana Peiró, Alicante, Spain - Pharmacogenectics and individualizing drug treatment in chronic pain09:25-09:45 > Alain Eschalier, Clermont-Ferrand, France - “Analgesic effect of paracetamol: a new insight”
or “Paracetamol: a centrally-acting analgesic”09:45-10:00 > Jérôme Busserolles, Clermont-Ferrand, France - Epigenetic regulations and neuropathic pains10:00-10:30 Break
10:30-12:30 PERSONALIZING TREATMENT STRATEGIES IN ONCO-HEMATOLOGY DÍSZTEREM ROOM Chairs: Marc Ansari, Geneva, Switzerland / József Tímár, Budapest, Hungary10:30-10:40 > Marc Ansari, Geneva, Switzerland - Introduction10:40-11:05 > József Tímár, Budapest, Hungary - “Precision oncology” based on the genetic information of the primary tumor?11:05-11:30 > Céline Pallaud, Basel, Switzerland - Tyrosine kinase inhibitor in oncology11:30-12:05 > Joseph Ciccolini, Marseille, France - Pharmacogenetics of myelodysplastic syndromes: CDA status as a predictive marker
of clinical outcome in patients undergoing cytarabine and azacytidine therapy12:05-12:30 > Ettore Biagi, Milano, Italy - CAR therapy in hematological malignancies: facts and future challenges12:30-14:00 Lunch Break and ESPT General Assembly
14:00-18:00 CLINICAL IMPLEMENTATION OF PHARMACOGENOMICS DATA DÍSZTEREM ROOM14:00-15:30 Toward practical application of Big Data and Digital Health for personalised medicine: revolution is now Chairs: Patrice Denefle, Paris, France / Thomas Griesbacher, Graz, Austria14:00-14-15 > Patrice Denèfle, Institut Roche, France - Introduction14:15-14-40 > Uwe Diegel, Paris, France - The impact of digital health as a tool for clinical research14:40-15-05 > Scott Kahn, Illumina, USA - The role of Big Data in supporting clinician researchers for precision medicine15:05-15-30 > Andreas Posch, Siemens Healthcare, Erlangen, Germany - Patient-specific disease modeling for therapy decision support15:30-18:00 Specific Workshop and round table Chairs: Adrian Llerena, Badajoz, Spain / Ron van Schaik, Rotterdam, The Netherlands / Mária Judit Molnár, Budapest, Hungary With the participation of general practitioners, young clinicians, the ESPT board members and specialised colleagues,
the speakers of the big data session and specialised software translational companies Introduction15:30-15-45 > Ron van Schaik, Rotterdam, The Netherlands - The EuPIC initiative – Pre-emptive pharmacogenomics Targeted Cancer therapy15:45-16-05 > Paolo Marchetti, Roma, Italy - TBC 16:05-16-25 > Gérard Milano, Nice, France - Pharmacogenomics of DPD and clinical impact in cancer therapy16:25-16:40 > Discussion between clinicians and specialists Neurodegenerative diseases 16:40-17:00 > Mária Judit Molnár, Budapest, Hungary - Mitochondrial genomic variations and personalized treatment strategies17:00-17:20 > Magnus Ingelman-Sundberg, Stockholm, Sweden - Pharmacogenomics of Alzheimer and neurodegenerative diseases17:20-17:35 > Discussion between clinicians and specialists General discussion and Closing remarks17:35-18:00 > Adrian Llerena, Badajoz, Spain - Relevance of European drug regulation for clinical implementation
and all participants
Under the auspices of the Medical Section of the Hungarian Academy of Sciences
Scientific Programwww.esptcongress.eu
ESPT 2015Third ConferenceIntegration of Pharmacogenomics in clinical decision supportOctober 7-8-9, 2015Hungarian Academy of SciencesBudapest, Hungary
Committees
Thanks to our sponsors
GOLD SPONSORS
SILVER SPONSORS
SPONSORS
BRONZE SPONSORS
Institute
Congress VenueHungarian Academy of Sciences Budapest 1051 Budapest, Széchenyi István sqr. 9Tel. :[email protected]
Contact Organization
Com&Co Events Benjamin Richier: [email protected] Tel. : 33 (0)4 91 09 70 53
Hungarian Academy of Sciences BudapestGyörgy Németh: [email protected]ária Judit Molnár: [email protected]
• Ansari Marc, Geneva, CH
• Berecz Roland, Debrecen, HU
• Božina Nada, Zagreb, HR
• Cascorbi Ingolf, Kiel, DE
• Dumic Jerka, Zagreb, HR
• Ferrari Maurizio, Milan, IT
• Hubacek Jaroslav, Prague, CZ
• Jordan Bruce, Rotkreuz, CH
• Kovács Gábor L., Pécs, HU
• Llerena Adrian, Badajoz, ES
• Manolopoulos Vangelis G., Alexandroupolis, GR
• Marc Janja, Ljubljana, SI
• Meyer Urs A., Basel, CH
• Molnár Mária Judit, Budapest, HU
• Németh György, Budapest, HU • Oellerich Michael, Göttingen, DE
• Pallaud Céline, Basel, CH
• Paulmichl Markus, Salzburg, AT
• Semiz Sabina, Sarajovo, BIH
• Siest Gerard, Nancy, FR
• Simmaco Maurizio, Roma, IT
• Sperlágh Beáta, Budapest, HU
• Stankovic Sanja, Belgrade, SRB
• Van Schaik Ron H.N., Rotterdam, NL
• Visvikis-Siest Sophie, Nancy, FR
> Com&Co Events, Marseille, FR:
• Benjamin Richier
> INSERM Team and ESPT Office, Nancy, FR:
• Siest Gérard • Visvikis-Siest Sophie • Hiegel Brigitte • Durlin Anne • Ndiaye Ndeye Coumba • Stathopoulou Maria • Petrelis Alexandros • Aldasoro Arguinano Alex-Ander • Masson Christine • Chatelin Jérôme • Xie Ting • Ulmer Patricia
• Németh György, Budapest, HU
• Molnár Mária Judit, Budapest, HU
• Kovács Gábor L., Pécs, HU
> Chair: • Maurizio Simmaco, Italy
> Members: • Stankovic Sanja, Serbia • Peiró Ana, Spain
• Ndeye Coumba Ndiaye, France
• Szalai Csaba, Hungary
SCIENTIFIC COMMITTEE ORGANIZATION COMMITTEE LOCAL ORGANIZATION
POSTER COMMITTEE
Tuesday 6 OctoberKÉPES TEREM
13:30-20:00 ESPT Board meetingFollowed by a dinner
Wednesday 7 OctoberFELOLVASÓTEREM13:15-15:15Committee Pediatric individualised treatment in oncology and hematology> Janja Marc
KÉPES TEREM
14:00-15:00Committee on pharmacogenomics information for generic drugs > Vangelis Manolopoulos
15:30-16:30Division Education and Course > Vangelis Manolopoulos /
Janja Marc
Thursday 8 OctoberFELOLVASÓTEREM ROOM08:00-09:00ESPT Corporate Members
KÉPES TEREM09:30-10:30DMPT Editorial board
14:15-15:15Committee Drug Transporters > Ingolf Cascorbi
Friday 9 OctoberKÉPES TEREM09:00-10:00Division Scientific and Clinical Implementation > Ron van Schaik / Janja Marc
10:00-12:00Joint EFLM / ESPT Working Group Meeting
DÍSZTEREM13:00-14:00ESPT General Assembly • Ordinary• Extraordinary
KÉPES TEREM17:00-18:30VEGF Consortium Second meeting
Specific meetings planned in Budapest
Under the auspices of the Medical Section of the Hungarian Academy of Sciences
Scientific Programwww.esptcongress.eu
ESPT 2015Third ConferenceIntegration of Pharmacogenomics in clinical decision supportOctober 7-8-9, 2015Hungarian Academy of SciencesBudapest, Hungary
Committees
Thanks to our sponsors
GOLD SPONSORS
SILVER SPONSORS
SPONSORS
BRONZE SPONSORS
Institute
Congress VenueHungarian Academy of Sciences Budapest 1051 Budapest, Széchenyi István sqr. 9Tel. :[email protected]
Contact Organization
Com&Co Events Benjamin Richier: [email protected] Tel. : 33 (0)4 91 09 70 53
Hungarian Academy of Sciences BudapestGyörgy Németh: [email protected]ária Judit Molnár: [email protected]
• Ansari Marc, Geneva, CH
• Berecz Roland, Debrecen, HU
• Božina Nada, Zagreb, HR
• Cascorbi Ingolf, Kiel, DE
• Dumic Jerka, Zagreb, HR
• Ferrari Maurizio, Milan, IT
• Hubacek Jaroslav, Prague, CZ
• Jordan Bruce, Rotkreuz, CH
• Kovács Gábor L., Pécs, HU
• Llerena Adrian, Badajoz, ES
• Manolopoulos Vangelis G., Alexandroupolis, GR
• Marc Janja, Ljubljana, SI
• Meyer Urs A., Basel, CH
• Molnár Mária Judit, Budapest, HU
• Németh György, Budapest, HU • Oellerich Michael, Göttingen, DE
• Pallaud Céline, Basel, CH
• Paulmichl Markus, Salzburg, AT
• Semiz Sabina, Sarajovo, BIH
• Siest Gerard, Nancy, FR
• Simmaco Maurizio, Roma, IT
• Sperlágh Beáta, Budapest, HU
• Stankovic Sanja, Belgrade, SRB
• Van Schaik Ron H.N., Rotterdam, NL
• Visvikis-Siest Sophie, Nancy, FR
> Com&Co Events, Marseille, FR:
• Benjamin Richier
> INSERM Team and ESPT Office, Nancy, FR:
• Siest Gérard • Visvikis-Siest Sophie • Hiegel Brigitte • Durlin Anne • Ndiaye Ndeye Coumba • Stathopoulou Maria • Petrelis Alexandros • Aldasoro Arguinano Alex-Ander • Masson Christine • Chatelin Jérôme • Xie Ting • Ulmer Patricia
• Németh György, Budapest, HU
• Molnár Mária Judit, Budapest, HU
• Kovács Gábor L., Pécs, HU
> Chair: • Maurizio Simmaco, Italy
> Members: • Stankovic Sanja, Serbia • Peiró Ana, Spain
• Ndeye Coumba Ndiaye, France
• Szalai Csaba, Hungary
SCIENTIFIC COMMITTEE ORGANIZATION COMMITTEE LOCAL ORGANIZATION
POSTER COMMITTEE
Tuesday 6 OctoberKÉPES TEREM
13:30-20:00 ESPT Board meetingFollowed by a dinner
Wednesday 7 OctoberFELOLVASÓTEREM13:15-15:15Committee Pediatric individualised treatment in oncology and hematology> Janja Marc
KÉPES TEREM
14:00-15:00Committee on pharmacogenomics information for generic drugs > Vangelis Manolopoulos
15:30-16:30Division Education and Course > Vangelis Manolopoulos /
Janja Marc
Thursday 8 OctoberFELOLVASÓTEREM ROOM08:00-09:00ESPT Corporate Members
KÉPES TEREM09:30-10:30DMPT Editorial board
14:15-15:15Committee Drug Transporters > Ingolf Cascorbi
Friday 9 OctoberKÉPES TEREM09:00-10:00Division Scientific and Clinical Implementation > Ron van Schaik / Janja Marc
10:00-12:00Joint EFLM / ESPT Working Group Meeting
DÍSZTEREM13:00-14:00ESPT General Assembly • Ordinary• Extraordinary
KÉPES TEREM17:00-18:30VEGF Consortium Second meeting
Specific meetings planned in Budapest
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