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Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health and Medical Research Council Senior Research Fellow, Macquarie Centre for Cognitive Science (MACCS), Macquarie University, Sydney, Australia
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Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Apr 01, 2015

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Page 1: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Treatment of Word retrieval impairments:

Do we know which tasks work

for whom and why?

Continued!

Associate Professor Lyndsey Nickels

National Health and Medical Research Council

Senior Research Fellow,

Macquarie Centre for Cognitive Science (MACCS),

Macquarie University, Sydney, Australia

Page 2: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

How do we decide which treatment?

Each different level of breakdown in word production will be best remediated by a different type of treatment

(e.g. Hillis & Caramazza, 1994; Nettleton & Lesser, 1991)

• impaired word meaning (semantics)

→ treatment focusing on meaning

• impaired retrieval of the phonological form from semantics

→ treatment focusing on providing/accessing the phonological form

• impaired phoneme level/phonological encoding→ treatment focusing on phonemes

Remember…. Therapy for word

retrieval DOES NOT have to include word retrieval

Page 3: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

How do we decide which treatment?

Each different level of breakdown in word production will be best remediated by a different type of treatment

(e.g. Hillis & Caramazza, 1994; Nettleton & Lesser, 1991)

• impaired word meaning (semantics)

→ treatment focusing on meaning

• impaired retrieval of the phonological form from semantics

→ treatment focusing on providing/accessing the phonological form

• impaired phoneme level/phonological encoding→ treatment focusing on phonemes

Page 4: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

What treatment is appropriate?

Semantic impairments

The most successful therapy seems to involve exploring the semantic attributes of a stimulus.

e.g. Boyle & Coelho, 1995.

Coelho, McHugh & Boyle, 2000.

Hillis, 1991, 1998.

Nickels & Best, 1996.

Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Page 5: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy for semantic impairments

e.g. Semantic feature analysis (SFA) (Boyle & Coelho, 1995; Coelho, McHugh & Boyle, 2000)

• name a picture• generate features relating to …..

Exploring semantic attributes of a stimulus

GROUP: is an ANIMAL

USE: is used for protection

ACTION: does what? Barks

LOCATION: is found at home

ASSOCIATION: reminds me of a kennel

Can we be sure this is effective?

Not entirely … they use very small numbers of items in

the sets, and examine changes in performance

using visual inspection with no statistics

Page 6: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy for semantic impairments (cont)

e.g. Nickels & Best (1996) AER

“Relatedness judgements” (with feedback)

Statistically significantly improved naming of treated and untreated stimuli

Nickels & Best argue that feedback is

critical to obtaining generalisation to untreated items

Page 7: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy for semantic impairments (cont)

e.g. Hillis (1991, 1998) HG.

Red vs yellowRound vs oval

Thin skin vs thick skinSweet vs sour

Lemon

Page 8: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy for semantic impairments (cont)

e.g. Hillis (1991, 1998) HG. • name a picture, • if and semantic error was produced, • → drawing of error • compare drawing to the target picture • discuss semantic distinctions

• Significant improvement in written naming (treated)• also in spoken naming and word comprehension • Improvement of treated items and untreated items in the

same semantic category(but this may just be that untreated items appeared in therapy)

Page 9: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

How does the treatment for

semantic impairment work?

Doesn’t it improve the

semantic impairment?

If so what would the effects be?

Page 10: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonological Output Lexicon

Speech output

Phonological Output Buffer

Lexical Semantics

Writing

Heard SpeechPrint

Idea, Picture, or seen object

Lexical Semantics

Page 11: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonological Output Lexicon

Speech output

Phonological Output Buffer

Lexical Semantics

Writing

Heard SpeechPrint

Idea, Picture, or seen object

Lexical Semantics

Page 12: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonological Output Lexicon

Speech output

Phonological Output Buffer

Lexical Semantics

Writing

Heard SpeechPrint

Idea, Picture, or seen object

Lexical Semantics

Page 13: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonological Output Lexicon

Speech output

Phonological Output Buffer

Lexical Semantics

Writing

Heard SpeechPrint

Idea, Picture, or seen object

Lexical Semantics

Semantic therapy for semantic

impairments should improve

all modalities

But although this was true for

Hillis’ study with HG, it was not

for AER.Improvement in all

modalities only occurs if treatment improves semantic

processing

Page 14: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

How did the authors think these treatments for semantic impairments were having their effects?

Hillis (1998) “improvement at the semantic level itself – perhaps through increased specificity of semantic representations of trained items”

Coelho et al (2000) - a strategy for word retrieval“by activating the semantic network surrounding the target word, that word may be activated above its threshold, thereby facilitating retrieval”

Nickels and Best (1996)

“the use of a strategy (which may be unconscious) of exploring the semantics of an item … which facilitates retrieval of that item (perhaps by increasing the semantic information addressing the output lexicon…)”

Consistent with improvement

across modalities

Consistent with improvement

restricted to speech production

Page 15: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

• Semantic tasks– Those tasks which involve focusing on word meanings

• Semantic tasks may be used to treat semantic impairments– Those tasks which seem to most often improve semantic

impairments involve reflecting on semantic features

– However even then they may NOT improve semantics itself but may instead provide a strategy for improving word retrieval.

Didn’t we contrast semantic impairments

and post-semantic word retrieval impairments?

Semantic tasks and semantic impairmentsHold on! How can

therapy for semantic impairments improve word retrieval without improving semantics

Yes, but semantic impairments cause word

retrieval impairments …

Page 16: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Post semantic word retrieval impairment

Page 17: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantic impairment

Page 18: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Sem impairment

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Semantic impairment

Page 19: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Semantic impairment also leads to a

reduction in activation at the word form level

Semantic impairment

Although, as we will see, this is usually

only the case in people with less severe semantic

impairments.So tasks can be

effective in improving word

retrieval WITHOUT improving the

semantic impairment

Page 20: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

SUMMARY: What treatment is appropriate?

Semantic impairments

The most successful therapy seems to involve exploring the semantic attributes of a stimulus.

e.g. Boyle & Coelho, 1995.

Coelho, McHugh & Boyle, 2000.

Hillis, 1991, 1998.

Nickels & Best, 1996.

Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Any questions?

Page 21: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy for semantic impairments or semantic tasks as therapy?

• Virtually all tasks involve semantic processing• Some focus on semantic processing to a greater extent

(we tend to refer to these as semantic tasks)

e.g.odd one out

(spoken or written) word to picture matching

These tasks are widely used in the remediation of word-retrieval impairments, however, their use is not restricted to those individuals with semantic impairments.

word-picture verification

Page 22: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantic tasks for improving word retrieval

The use of semantic tasks is not restricted to individuals with semantic impairments…...

semantic tasks can improve word production even for those individuals with good semantic processing and even when the tasks are performed accurately

(e.g. Nickels & Best, 1996).

…. In fact they are probably more likely to improve word production for those with relatively less semantic impairment – those with ‘post-semantic lexical retrieval impairments’.

Page 23: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

What treatment is appropriate?

Word retrieval impairments

Tasks focusing on semantics and phonology

- improve word retrieval

e.g. Howard et al 1985

Nickels & Best 1996 Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Page 24: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

What treatment is appropriate?

Word retrieval impairments

Tasks involve activation of both semantics and phonology

But may focus more on semantics….

Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Page 25: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

What treatment is appropriate?

Word retrieval impairments

All the tasks involve activation of both semantics and phonology

But may focus more on semantics

or phonology

Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Repeat “kangaroo”

It starts with /k/

Page 26: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

What treatment is appropriate?

Word retrieval impairments

All the tasks involve activation of both semantics and phonology

They produce long lasting, item specific effects in the majority of individuals with impaired activation of the correct target in the phonological lexicon

Improves likelihood of the target being sufficiently activated to be retrieved successfully.

Phonological Output Buffer

Speech

Phonological Output Lexicon

Lexical Semantics

Page 27: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Let’s explore these tasks that improve word retrieval in

more detail

Page 28: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

“Semantic” tasks as therapy

Word-picture matching

Word-picture verification

Widely effective (Howard et al, 1985; Marshall et al, 1989)

Long lasting effects (Pring et al., 1990)

Generally, lasting effects are item specific

These tasks typically don’t require word

production but improve naming at a later point

nevertheless

The tasks work best with people that can do them easily (people with

less of a semantic problem)

Page 29: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Howard et al (2006)

Compared the efficacy of word-picture matching with related and unrelated distractors

(related distractors = deeper processing = more effective?)

How important is the emphasis on

semantic processing?

Page 30: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Howard et al (2006)

Compared the efficacy of word-picture matching with related and unrelated distractors

All incorrect before word-picture matching

After word-picture matching

Related distractors: 45% correct

Unrelated distractors: 50% correct

Controls: 30% correct

How important is the emphasis on

semantic processing?

No evidence that deeper semantic processing

improves efficacy of word-picture matching

Not even for those with more severe

semantic impairments?

Page 31: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Howard et al (2006)

Compared the efficacy of word-picture matching with related and unrelated distractors

All incorrect before word-picture matching

After word-picture matching

Less sem imp. More sem imp.

Related distractors: 50% 40%

Unrelated distractors: 60% 40%

Controls: 40% 23%

How important is the emphasis on

semantic processing?

No evidence that deeper semantic processing improves efficacy of

therapy: not even for those with more severe semantic impairments

Page 32: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Martin, Laine et al (2000, 2003, 2004, 2005) ‘Contextual Priming’

Compared the efficacy of naming/repetition in the context of semantically related distractors and unrelated distractors.

How important is the emphasis on

semantic processing?

Page 33: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Martin, Laine et al (2000, 2003, 2004, 2005) ‘Contextual Priming’

How important is the emphasis on

semantic processing?

Page 34: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Martin, Laine et al (2000, 2003, 2004, 2005) ‘contextual priming’

Compared the efficacy of naming/repetition in the context of semantically related distractors and unrelated distractors.

- Naming is worse at the time with semantically related distractors.

- Naming is improved no more (at a later point) with semantically related distractors.

How important is the emphasis on

semantic processing?

No evidence that a semantic context

improves efficacy of therapy

Page 35: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

How important is the emphasis on

semantic processing?

Not as important as we thought!

• Tasks which have traditionally been labelled ‘semantic’, such as word-picture matching are equally effective with unrelated items.

• Adding a semantic context to a (naming/repetition) task does not make it more effective.

Page 36: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Word form is usually provided.

e.g. Le Dorze et al (1994)

“Show me the octopus”

“Show me the mollusc with long legs”

How important is the phonological form in the semantic task?

Most probably critical to its effectiveness

Page 37: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Therapy: The application of a

technique several times, over days, weeks

or months

Immediate Cueing effects: The effect of a technique at the time of

its application

Nickels, McDonald, Makin, Moses & Taylor –Facilitation Experiments

What is a facilitation

experiment?

It looks at the effect of a task performed ONCE on

another task at a later point and contrasts with…

Page 38: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Cueing, Facilitation, Therapy

“k”

kangaroo

Page 39: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Cueing, Facilitation, Therapy

“k”

kangaroo

….later

Page 40: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Cueing, Facilitation, Therapy

“k”“k”

“k”“k”

“k”“k”

“k”“k”

“k”

kangaroo

Page 41: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Nickels, McDonald, Makin, Moses & Taylor –Facilitation Experiments

Phonological

Repetition

“kangaroo”

Semantic without the word form

Feature verification

Does it hop?

Page 42: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Nickels, McDonald, Makin, Moses & Taylor –Facilitation Experiments

Name 300 pictures until 95 failed (10 second limit)

Sort the failed items into 3 (frequency & length)matched sets

Facilitation Task 1 Facilitation Task 2 Control

Facilitation

Name all 3 sets of pictures+ 30 easy fillers

1 week later

10 mins later

Page 43: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing repetition and a semantic task with no word form

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Page 44: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing repetition and a semantic task with no word form

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Page 45: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing repetition and a semantic task with no word form

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semanticphonological

Very little benefit from a semantic task without the word form for most

individuals

Page 46: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantic tasks without the word form

We also looked at the same tasks used as therapy with 4 individuals with aphasia

… once again, semantic tasks without the word form had little benefit

…. for example….

DRS

8 sessions of semantic therapy (feature verification)

over 2-3 weeks

Before each therapy session named all those items that were to be treated, and a set of control pictures (50 items in each set).

Page 47: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

DRS - Semantic Therapy

0

5

10

15

20

25

30

35

40

1 2 3 4 5 6 7 8

daily pretests

nu

mb

er c

orrect

( /5

0)

no. correct THERAPY

no. correct CONTROL

Linear no. correct THERAPY

Linear no. correct CONTROL

McNemar Day 1 vs Day 8

Wilcoxon 1 sample

Sem Treat ns 0.028773653

Sem control p= 0.0117 0.04377147

Sem treat vs sem control Wilcoxon 2 sample NS

No extra benefit from the

semantic task

But the untreated items seem to improve.....

Spontaneous recovery?Generalisation?

Benefits from repeated naming attempts?

Page 48: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

0

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35

40

Pre-test 1 Pre-test 2 Post sem 1 Post sem 2

Treated (sem)

Naming control

Unseen

Page 49: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

0

5

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20

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30

35

40

Pre-test 1 Pre-test 2 Post sem 1 Post sem 2

Treated (sem)

Naming control

Unseen

Treated items and repeatedly named items

improve to the same degree – so there is no specific benefit from the

semantic task

Page 50: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

0

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20

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Pre-test 1 Pre-test 2 Post sem 1 Post sem 2

Treated (sem)

Naming control

Unseen

Treated items and repeatedly named items

improve to the same degree – so there is no specific benefit from the

semantic task

The improvement from naming controls isn’t

generalisation or spontaneous recovery (unseen controls don’t

improve) – but benefit from repeated attempts at

naming

Page 51: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Summary: semantic tasks in word retrieval

• Degree/depth of semantic processing appears not to be critical (Howard et al)

• Presenting tasks in a semantic context can interfere short-term and mostly has no long term advantage over presentation in unrelated contexts (Martin, Laine et al)

• Presence of phonological form appears critical in most cases (Le Dorze et al; Nickels et al: facilitation studies, DRS therapy study)

…… and so to Phonological tasks

Any questions?

Page 52: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

“Phonological” tasks

• Repetition of target• Reading aloud• Phonological & orthographic cueing• Rhyme judgements • Syllable and phoneme counting• Phoneme segmentation• Anagrams

…….but nearly always in the presence of the picture.

Again we need to remember the distinction between the nature of

the task and the nature of the impairment…. Here we are talking about phonological tasks but NOT impairments to the phoneme level.

Page 53: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonological tasks and word retrieval

• Widely argued to be the most appropriate for impairments in retrieval of (or damage to) the phonological form from the phonological output lexicon (e.g. Hillis & Caramazza, 1994; Miceli,et al, 1996; Nettleton & Lesser, 1991)

Miceli et al (1996): as these tasks focus at the level of activation of individual entries in the phonological output lexicon, their effects should be item specific

– a result of ‘priming’ retrieval of the phonological form.

Page 54: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

For many years ‘semantic’ tasks were thought to be

more effective than ‘phonological’ tasks in

improving word retrieval

How true is this?

Page 55: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing repetition and a semantic task with no word form

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phonological

Page 56: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing repetition and a semantic task with no word form

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semanticphonological

Very little benefit from a semantic task without

the word form … repetition is almost

always more beneficial

Page 57: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

DRS - Phonological Therapy

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daily pretests

nu

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orrect (

/50)

No. correctTHERAPY

no. correctCONTROL

Linear no.correctTHERAPY

Linear no.correctCONTROL

McNemar Day 1 vs Day 8

Wilcoxon 1 sample

Phon Treat p= 0.0001 < .0001Phon control p= 0.0042 0.002304428

Phon treat vs phon control

Wilcoxon 2 sample

p(1 tail) =.048

Significant extra benefit from the repetition task

Page 58: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

For many years ‘semantic’ tasks were thought to be

more effective than ‘phonological’ tasks in

improving word retrieval

This seems NOT to be true in general, particularly if

the semantic task does not include the word form

Page 59: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantic & phonological treatments: an overstated distinction?

• BOTH have semantic and phonological components– Semantic tasks without the phonological form are generally

not effective

• Howard (2000)

– tasks having the same effects in the same way

• Strengthening the connections between semantics and phonological form when both are simultaneously active

• equivalent effects for semantic and phonological tasks for most individuals

Page 60: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Page 61: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Page 62: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Semantics

Object, picture or idea

purrs

cat dog rabbit fish

barksfur pet4-legs scales

houserobin

Phonological Lexicon

PhonologicalBuffer/

Phonemesæ td o gk

Page 63: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

‘Semantic’ and ‘phonological’ tasks are working in similar ways

By strengthening the connections between

semantics and word form by activating both

semantics and phonology

Page 64: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.
Page 65: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

The role of effort and error

• Effortful >benefit than automatic? – Greater semantic processing

• Errorless >benefit than errorful?

How does amount of ‘effort’ or accuracy in

a task affect the benefit for naming?

Page 66: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing Phonological Tasks

“kangaroo”

Repetition

Effortless, ‘shallow’ processing,

error reducing

“k”

Phonemic cueing

Effortful, deeper processing,

errorful

Page 67: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Method

Name 300 pictures until 95 failed (10 second limit)

Sort the failed items into 3 (frequency & length)matched sets

Facilitation Task 1 Facilitation Task 2 Control

Facilitation

Name all 3 sets of pictures+ 30 easy fillers

1 week later

10 mins later

Page 68: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

-0.10

0.00

0.10

0.20

0.30

0.40

0.50

FM

E

JNI

KC

C

PS

J

DR

S

JUE

SJS

JMM

DIP

MC

B

WV

K

FA

B

JOW

MF

T

SM

G

Mea

n

Phon Cues

Repetition

*

*

*

*

*

**

*

Facilitation effect compared to control pictures:Errorless/Automatic (Repetition) vs Errorful /Effortful (Phonemic cues)

Page 69: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

-0.10

0.00

0.10

0.20

0.30

0.40

0.50

FM

E

JNI

KC

C

PS

J

DR

S

JUE

SJS

JMM

DIP

MC

B

WV

K

FA

B

JOW

MF

T

SM

G

Mea

n

Phon Cues

Repetition

Facilitation effect compared to control pictures:Errorless/Automatic (Repetition) vs Errorful /Effortful (Phonemic cues)

*

*

*

*

*

**

*

Page 70: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Comparing Phonological Tasks

“kangaroo”

Repetition

Effortless, ‘shallow’ processing,

error reducing

“k”

Phonemic cueing

Effortful, deeper processing,

errorful

> benefit than

No need for it to be effortful to be

helpful – FOR MOST PEOPLE

Well, repetition is better and it does improve more BUT

the proper comparison is within

a task ….

Is errorless (or error reducing) better than errorful?

Page 71: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Fewer errors means greater benefit?

Repetition is more error-free than cueing… but the proper comparison is within a task

Cueing

Do the people who are more accurate with cueing (at the time) have more benefit for naming (later)?

-0.2

-0.1

0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

MFT

DRSFAB

FME

KCCSJS DIP JN

IJM

MM

CBPSJ

JUE

WVK

SMG

JOW

Phon Cue - Facilitationaccuracy

Phon Cue naming benefit

Page 72: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Errorless items benefit more?

Repetition is more error-free than cueing… but the proper comparison is within a task

Cueing• no significant correlation between success of

the cue during facilitation and benefit of cueing for subsequent naming.

• i.e. errorless is not better than errorful for cueing.Why did we think errorless might be better in the first

place?

Page 73: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Errorless learningHypothesis• Remediation is more effective if errors are prevented

- the act of producing an error may strengthen the incorrect association, and make the correct response less likely to occur.

History• Animal learning (Terrace, 1963)

• Children with developmental learning difficulties (e.g. Sidman & Stoddard, 1967).

• Acquired memory impairments (amnesia) (e.g. Baddeley & Wilson, 1994)

Page 74: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Errorless learning and anomia treatment

• Fillingham et al (2003)“error reducing techniques do have positive effects for patients with

word finding difficulties. As yet there is limited information on which to judge whether this technique is significantly advantageous over errorful approaches” (p358).

• Fillingham et al (2005, 2006)– No significant difference between errorless (repetition) and errorful

(cueing) tasks.

• Abel et al (2005)– No significant difference between increasing and vanishing cues

methods (errorful vs error reducing).

BUT nonetheless repetition may be more

beneficial than phonemic cueing for

many people

There appears to be no difference between

errorful and errorless techniques in aphasia

Remember that this will all depend on the processing strengths and weaknesses of

the aphasic individual

Page 75: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Any questions?

•How semantic & phonological tasks

work

•Error & Effort

Page 76: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Generalisation in the treatment of word retrieval.

• the most successful treatment is one which effects improvement not only for the items used in therapy but also for any other item, in any other context.

• many treatments produce clear long lasting effects on the treated items, generalisation to untreated items is

less common, and when obtained, often less robust (e.g. Nickels and Best, 1996b)

Page 77: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

When perceived generalisation is actually an effect of (assessment during) treatment!

DRS

0

5

10

15

20

25

30

35

40

Pre-test 1 Pre-test 2 Post sem 1 Post sem 2

Treated (sem)

Naming control

Page 78: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

When perceived generalisation is actually an effect of (assessment during) treatment!

DRS

0

5

10

15

20

25

30

35

40

Pre-test 1 Pre-test 2 Post sem 1 Post sem 2

Treated (sem)

Naming control

Unseen

Page 79: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

When perceived generalisation is actually an effect of (assessment during) treatment!

Howard et al (1985) “Naming controls”• naming daily but NOT treated• Improved significantly

• Widely interpreted as generalisation of treatment effects– more probably the result of repeated attempts at naming (Howard, 2000)

Nickels (2002) JAW- Repeatedly attempted to name a set of pictures (daily for a

week)- Significantly improved naming

Page 80: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Practice makes (closer to) perfect:trying to name helps naming!

HOW?- some names will be successfully retrieved on one occasion but not on

another.

- When, by chance, an individual produces a picture name successfully, both the semantic representation and the phonological representation for that item are simultaneously active.

- This will then strengthen the mapping for that item, making it more likely that the word will be produced correctly on a subsequent occasion (which will again strengthen the mapping).

- Over time, more items will have strong enough mappings to be produced accurately on every occasion

Or perhaps just partially activating the phonological

representation when trying to name is enough to strengthen

the mappings

More work needs to be done to determine who

this works for, how close together naming

attempts have to be etc etc

But it could have important

implications-Use it or lose it- (Attempts at)

conversation might improve word retrieval- (Trying to) talk about the same topics may be

better

Page 81: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

When generalisation is a reflection of (strategic?) changes in processing

• Semantic tasks (with semantic disorders) Techniques promoting reflection on semantic properties may be better

viewed as teaching a strategy, albeit an unconscious strategy.

• Phonological tasks– Best (2006) examined who showed generalisation using a cueing

treatment – it was those individuals with relatively more of a phonological impairment (and less semantic impairment)

• Self-cueing– E.g. phonologically mediated orthographic cueing

Page 82: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Mostly generalisation is limited…

Therefore the emphasis is on the clinician to ensure that all items used in therapy are functionally relevant and chosen in collaboration with the person with aphasia.

Nickels et al – in progress

‘Home Programme’

• Using the most successful task (repetition)

• 60-100 items chosen by the person with aphasia as being words they wanted to be able to say.

• Therapy presented by computer in powerpoint

• ‘Structured’ conversation used to evaluate carry-over from naming to conversation

Page 83: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.
Page 84: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.
Page 85: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Treatments aimed at remediating word production impairments

Tasks can be • effective (e.g. Hillis & Caramazza, 1994; Howard et al, 1985b),

• produce durable effects (e.g. Pring et al, 1990),

• be administered by clinician &/or computer (e.g. Fink et al, 2002)

• be obtained on verbs & nouns (e.g. Murray & Karcher, 2000; Raymer and Ellsworth, 2002).

• carry-over into connected speech & conversation (e.g. Hickin et al, 2002),

BUT

treatment tasks are not invariably effective

Page 86: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Do impairment-based treatments impact on functional skills and increase activity &

participation?• word retrieval/production underlies every attempt at verbal

communication hence improving word retrieval impairments is of course functionally relevant

Simplistic and/or fundamentally misguided

BUT

the importance of an increased ability to name treated items following therapy should not be underestimated

Hillis (1998) HG

- small change in impairment – significant gains in activity & participation with the use of functionally relevant personal items (Bacardi & Coke!)

Page 87: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Do impairment-based treatments impact on functional skills and increase activity &

participation?• Yes …. (functional gains can be achieved)• but…. (they are by no means guaranteed)

• few studies that have formally evaluated the effects on disability of impairment-based remediation.

• It seems particularly important given the prevalence of item specific effects that remediation should include personally relevant stimuli.

Page 88: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Any questions?

•Generalisation•Effects of repeated naming•Functional relevance

Page 89: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

So far we’ve talked about tasks that aim to improve the underlying

word retrieval impairment – some

tasks may work in other ways too

Lets take another look

at cueing

Page 90: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.
Page 91: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

Page 92: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

/t/

Page 93: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

tomato

/t/

Page 94: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

T

Page 95: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

tomato

TLetter cueing has been found to have the same effects as phonemic cues

– both immediate and longer term benefits for naming for some individuals

(Best et al. 2002)

Page 96: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

Some individuals can generate their own orthographic

cues

Page 97: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

TOMATO

Page 98: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

tomato

TOMATO

How does this work?

Page 99: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

?

T -> /t/

How does this work?

Phonologically-mediated self-cueing (e.g. Bachy-Langedock & DePartz, 1986; Nickels, 1992)

Page 100: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

tomato

T -> /t/

Phonologically-mediated self-cueing (e.g. Bachy-Langedock & DePartz, 1986; Nickels, 1992)

Requires phonological

cueability

Requires access to the written

form when the spoken form is

unavailable Requires an ability to convert

letters into sounds

Page 101: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Phonologically-mediated self-cueing (e.g. Bachy-Langedock & DePartz, 1986; Nickels, 1992)

Requires phonological

cueability

Requires access to the written

form when the spoken form is

unavailable Requires an ability to convert

letters into sounds

Can use a computer

cueing aid to do the conversion

Can be retaught

Page 102: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Generating phonemic cues from the initial letter

1. Spoken naming

2. Written naming

3. Convert letters to sounds

dog

Nickels (1992) TC

Page 103: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Generating phonemic cues from the initial letter

1. Spoken naming

2. Visualise written word

3. Sound out initial letter

& cue word production

Nickels (1992)

retaught letter-sound correspondences

ddog

dog

• This improved TCs spoken naming to almost the same level as his written naming. • He used this spontaneously in conversation.• Could be (and was) used for any word he was trying to retrieve (only fails for words with irregular initial letters e.g. onion, Cinderella)

Page 104: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Using a computer to generate phonemic cues from the initial letter

e.g. Bruce & Howard (1987); Best et al. (1997)

/d/

dog

d

3. Press letter 2. Visualise first letter

4. Computer produces phoneme

5. Cue word production

1. Spoken naming

Page 105: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Generating phonemic cues

When spoken naming

IF individuals can identify initial letter

convert letters to sounds

and are phonemically cueable

Then they can generate their own cues.

If unable to convert letters to sounds

- Can be retaught

- Can use computer generated cues

- may be able to use the letters without converting to sounds – Direct orthographic cueing.

Page 106: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Direct Orthographic Cueing

SD: Howard & Harding (1998)

• impaired access to the phonological output lexicon (good semantics)• Unable to form letters

• Given an alphabet board – naming improved dramatically

• Was not using phonological mediation• unable to convert letters to sounds• unaffected by initial letter regularity (e.g. onion; eye)

Page 107: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Self-generated orthographic cues

When spoken naming

IF individuals can identify initial letter

They may be able to use direct orthographic cueing

• If they are phonemically cueable

They may be able to use a computer to generate the cues

• If they can (or be taught to) convert letters to sounds

They may be able to generate their own phonological cues.

Any questions?

•Self-generated cues

Page 108: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

When things don’t go the way you

planned!

Page 109: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Using a cueing aid as therapy – who benefits?

Best, Howard, Bruce & Gatehouse (1997)• 13 individuals treated with the cueing aid

• predicted benefit only for those who when spoken naming

can identify initial letter & are phonemically cueable

•They should be better at naming with the aid than without it (this is providing the cues).

• Only two individuals had both skills

After treatment:

Only 1 individual had better naming with the aid than without.

BUT 12 showed significant improvement in naming.

WHY???

Page 110: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Why does treatment with a cueing aid help individuals who are not predicted to benefit?

Treatment tasks can work in different ways for different individuals

Multicomponent treatment • orthography • phonology • semantics (presentation of the picture and

attempted naming).Only one individual was

helped by the aid providing the cue - for many others this was a standard word

retrieval therapy

Phonemic cueingRepetition in the presence of the

picture

Page 111: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Cueing aid reorganising the naming system: JOW (Best et al, 1997)

• Substantial and long-lasting effects of treatment• Improvement in treated and untreated items

• treatment drew attention to the relationship between orthography and phonology

• altered automatic (not strategic) processes in his word retrieval

• A direct orthographic cueing mechanism

Page 112: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Why does treatment with a cueing aid help individuals who are not predicted to benefit?

Treatment tasks can work in different ways for different individuals

…. especially when they are multicomponentHow tasks actually work may not be

how you planned them

to!And sometimes they don’t work

even though you would

predict they should!

Page 113: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

RECAP

BEFORE THE BREAK• Assessment of level of breakdown in word production• Methodological issues in evaluating treatment

Page 114: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

RECAP (continued)

AFTER THE BREAK• Improving naming when there are semantic impairments

– Exploring semantic features – It may work by providing a strategy to improve naming rather than

improving semantics itself.

• Word retrieval impairments– Semantic vs phonological tasks– Semantic tasks require the word form, depth of semantic

processing is not important– Phonological tasks are also effective– Tasks are working in the same way

• Effort & error– Tasks do not need to be effortful– There is no additional benefit from errorless performance

Page 115: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

RECAP (continued)• Generalisation

– Treatment for Word retrieval impairments usually result in item specific improvements

– but may generalise to conversation, and can produce effects on participation/quality of life

– Use of functionally relevant items is a priority– Repeated attempts at naming may improve word retrieval for some

individuals– Generalisation can result from strategic/compensatory approaches

• Self-generated Cues– Phonologically mediated/computer generated/direct orthographic

• Tasks may not always work the way you expect

• ALL OF THE ABOVE ARE GENERALISATIONS

– every person with aphasia is different and could be the exception to these general principles

Page 116: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Relationship between task, impairment and efficacy

Therapist’s dream = Prescription guide

“to unambiguously pair a particular functional impairment with a treatment task that has guaranteed success for that impairment”

Page 117: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Clinicians need to know what to do NOW!!!

• choose a therapy that has the best chance of succeeding

• Choose a task that has successfully improved naming for a wide variety of people with spoken word retrieval impairments

- multicomponent approaches (e.g. cueing hierarchies or multimodality/multi-task therapies – see e.g. Best et al, 1997; Hickin et al, 2002)

• Use pilot studies using different tasks for short periods (e.g. 1 week) to establish which tasks seem effective and which do not prior to continuing with the most effective therapies over longer period.

Page 118: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Prove that it works!

• ensure that it is possible to establish whether or not a particular therapy is effective by using a sound methodology.

We have a duty to be able to demonstrate that a therapy is effective to the individuals with aphasia, their families/friends/carers, those funding the treatment and not least to ourselves.

Page 119: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.

Thank you!

Any questions

or comments?

Page 120: Treatment of Word retrieval impairments: Do we know which tasks work for whom and why? Continued! Associate Professor Lyndsey Nickels National Health.