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Transport of Oxygenin Blood and tissue
uidsDR AMNA TAHIR
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DIFFUSION OF O!"#N FROM TH# A$%#O$ITO TH# &U$MONAR! 'A&I$$AR! B$OOD
• PO2 Of gaseous oxygen in the alveoli =
104 mm Hg
• PO2 Of venous blood entering the
pulmonary capillary at its arterial end =40mm Hg
• Initial pressure dierence= 104!40=
"4mm Hg• PO2 Of the blood rises to that of
alveolar air by the time the blood hasmoved a third of the distance throughthe capillary
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#p ta$e of oxygenby the pulmonary
blood
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&'()*PO'& O+ O,-%.) I) &H.
('&.'I(/ /OO
• 3 O+ the blood that enters theleft atrium 5ith PO
2= 104 mmHg
•
2 O+ the blood has passed thebronchial circulation 6 *H#)&./OO7 5ith PO
2=40 mmHg
•
8enous admixture of blood• PO2 of the blood pumped by
aorta = 9 mmHg
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DIFFUSION OF O!"#N FROMTH# RI&H#RA$ 'A&I$$ARI#S
INTO TH# TISSU# F$UID• PO2 at the arterial end= 9
mmHg
•
PO2 in the interstitial :uid thatsurround the tissue cells= 40mmHg
• &issue PO2 is determined by 2
factors1; 'ate of oxygen transport to
tissues in the blood
2; &he rate at 5hich the oxygen is
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DIFFUSION OF O!"#N FROM TH# RI&H#RA$'A&I$$ARI#S TO TH# TISSU# '#$$S
• Intracellular PO2 ranges 9!40
mmHg
•
(verage 2< mmHg• 1!< mmHg is reuired
• /arger safety factor
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'O/. O+ H.>O%/OI) I) O,-%.)
&'()*PO'&
• ? is carried in chemicalcombination 5ith Hb
•
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