Translation of genetic information.

TRANSLATION OF GENETIC INFORMATION

By: Ana Isabel Valencia Gómez

Molecular Biology2016

INTRODUCTION

Translation is protein synthesis guided by a mold

mRNA.

Protein synthesis involves the interaction of three types of

RNA molecules: mRNA, tRNA, rRNA and consists of 3 stages:

initiation, elongation and termination.

Repair system discovered in algae, new tools of biotechnology.

Novel 'repair system' discovered in algae may yield new tools for biotechnology.

Boyce Thompson Institute.July 29, 2016.

Repair system discovered in algae, new tools of biotechnology.

Algae C. reinhardtii can break the interrumping sequence from a

protein. It removes the insertions in proteins that alter their

function.

Repair system discovered in algae, new tools of biotechnology. 

Short version has the

ability to cut RNA.

Can be purified

starting from C. reinhardtii chloroplasts.

Repair system discovered in algae, new tools of biotechnology.

The most important finding: A long protein

RB47 without function may become short, by mixing

them with the algae chloroplasts on light.

Repair system discovered in algae, new tools of biotechnology.

STUDENT’S OBSERVATION

This discovery represents a breakthrough for the pharmaceutical industry because by this protein can

develop drugs with ability to activate or inhibit the function of

virus or bacteria with specific proteins , which could be important

for future cancer treatment.  

Stem cells of worms, humans more similar than expected.

Stem cells of worms, humans more similar than expected

Max Delbrück Center for Molecular Medicine in the Helmholtz Association

August 9, 2016

Stem cells of worms, humans more similar than expected.

The transient form of genetic information and RNA are processed in a similar manner in humans and in worms

Stem cells of worms, humans more similar than expected.

In worms are identified numerous alternative exons responsible for

stem cell-specific protein variants.

CELF: protein counteracts

MBNL by stimulating the production of

these variants.

Stem cells of worms, humans more similar than expected.

Was identified splicing processes that operate only in the stem cells of the worms.

Stem cells of worms, humans more similar than expected.

This is so interesting because planarian has a remarkable ability to regenerate any

part of the lost body through its many stem cells, and through this research

achievement demonstrate that they have similarities in the processes of RNA with humans, and maybe so can perform more complex experiments led to the ability of

regeneration applied to humans

STUDENT’S OBSERVATION

Medical utility

The new about the algae C. reinhardtii has a great importance

in the field of pharmacology therefore has significant medical

utility, if they were to develop drugs based on the mechanism of

action of this protein (RB47), it could activate and deactivate

proteins by the addition or removal of additional sequences. 

Medical utility  

The new about the stem cells in worms affect the medical advances for

future generations, because as this research achievement demonstrate

the similarity between stem cells human and worm, it can develop processes by which stem cells

eachother humans have regenerative capabilities.

Medical utility

Both studies have important for the field of modern medicine advances, because of his discoveries are so novel, useful and never mentioned

above.

Medical utility

The research done deal intron sequences, which can

lead to infer that there multiple research in this field to make that may be useful

in the field of the repair proteins and therefore

production of drugs

BIBLIOGRAPHYBoyce Thompson Institute. (2016, July 29). Novel 'repair system' discovered in algae may yield new tools for biotechnology: Chloroplasts can cut an interrupting insertion from a

protein, but only in the light. ScienceDaily. Retrieved September 4, 2016 from www.sciencedaily.com/releases/2016/07/160729092528.htm

Max Delbrück Center for Molecular Medicine in the Helmholtz Association. (2016, August 9). Stem cells of worms, humans more similar than expected: The same regulatory

mechanisms are active in the stem cells of flatworms and humans.ScienceDaily. Retrieved September 4, 2016

Martínez Sánchez , Lina María; Vargas Grisales, Natalia; Cardona Mejía, Laura; Osorio Ospina, Felipe; Ramírez Pulgarin , Sergio. (29 de Julio de 2015). Biología Molecular. En

Biología molecular (octava edición) (pág. 141). Medellín: Editorial Universidad Pontificia