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DR.U.SRINIVASA,M.Pharma, Ph.D DR.U.SRINIVASA,M.Pharma, Ph.D
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Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

May 07, 2015

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Page 1: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

DR.U.SRINIVASA,M.Pharma, Ph.DDR.U.SRINIVASA,M.Pharma, Ph.D

Page 2: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

KANTAKARI

Latin name: Solanum xanthocarpum

Sanskrit name: Kantakari

Vernacular names:

Eng- Kantakari ,

Hindi- Kateli,

Kan- Nelagulla

Page 3: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 4: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 5: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Biological source :

It consists of whole plant of Solanum

xanthocarpum ( solanum surattense )

Family : Solanaceae

It is very spiny herb,1.2 meters height found

all over India. The leaves are ovate or elliptic,

flowers bluish purple, fruits are globular.

Page 6: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Active constituents :

It contains Steroidal alkaloids Like

Solasodine, Solamergine, β- Solamergine,

Solasonine.

It also contains Sterols like Cycloartenol,

Norcarpesterol, Chlolestrol

Page 7: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Category : Expectorant

Uses :

1.Used in the treatment of bronchial asthma,

cough.

2. Used as an antipyretic drug

3. Used as an antidiabetic drug

4. Used as an anticancer drug

5.Solasodine has antispermatogenic activity,

hypochlolesterolaemic activity.

Page 8: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

SHATAVARI

Common Names:

Asparagus, Indian Asparagus,

Asparagus Racemosus.

Sanskrit and Hindi Names:

Shatavari, Satavar, Satmuli.

Page 9: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 10: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 11: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Biological source:

It consists of tuberous root of Asparagus

racemosus.

Family: Liliaceae.

Geographical Source: It is widely distributed

throughout the tropical regions of Africa,

Australia, Asia and India.

Page 12: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents : It contains Saponin glycosides

Two new steroidal saponins, shatavaroside

A and shatavaroside B together with a

known saponin, filiasparoside C, were

isolated from the roots of Asparagus

racemosus.

Page 13: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Five steroidal saponins, shatavarins VI-X,

together with five known saponins, shatavarin I,

shatavarin IV, shatavarin V.

Page 14: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses : Used as antioxytocic agent Used as refrigerant Used as demulcent Used as an aphrodisiac Used as an antiseptic Used in the treatment of leprosy and

Tuberculosis Used in rheumatism and gonorrhoea

Page 15: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

APAMARG

San -   Pratyakpuspa,

Ben - Apamg.

Hin - Chirchita , Latjira

Kan - Uttarani.

Mal - Katalati.

Page 16: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Biological source : It consists of the dried

entire plant of Acharanthes aspera

Family : Amaranthaceae

It is found throught out India and in the

South Andaman Islands

Page 17: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents : It contains alkaloids – Acharanthine and

betaine

It also contains triterpenoids saponins

– Oleanolic acid

Page 18: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses :

Useful in cough, asthama, bronchitis,

leprosy

Skin diseases, cardiac disorder

Page 19: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Guduchi Synonyms – Hindi - Amrita ,

English – Tinospora

Biological source –

Guduchi consists of the dried stems of the plant

Tinospora cordifolia

Family - Menispermaceae

G.S – Widely distributed throughout tropical and

subtropical india

Page 20: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 21: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 22: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents

1.Alkaloids-

Berberine, Palmatine, Jactrorhizine, Tinosporine,

Tembeterine

2. Glycosides-

Tinocardiside,Tinocardifolioside,Syringin,

Furanoid diterpene glucoside

3. Sesquiterpenoid – Tinocordifolin

Page 23: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

4. Diterpenoid lactones –

Furanolactone, Tinosporon, Columbin

5. β – Sitosterol

6. Choline

7.Tinosporic acid

8. Tinosporal

Page 24: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Category – Antipyretic, analgesic

Uses --

1.Used as an anticancer drug

2. Used as an antipyretic drug

3. Used in the treatment of asthama

4. Acts as an anti hypolipidaemic drug

5. Used as an antioxidant

6. Used as an antiulcer drug

7. Used as an antidiabetic drug

8. Used as an antihepatitis drug

Page 25: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Gokhru Ayurvedic name: Gokhru/Gokshura

Botanical source:

It consists of dried ripe seed of Tribulus terrestris

(chota gokhru), Pedalium murex (Bara gokhru).

Family: Zygophylaceae (chota gokhru)

Pedelliaceae ( Bara gokhru)

Page 26: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 27: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 28: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents

1.Saponin glycosides:

Steroid sapogenins -

Protodiosin, Hecogenin, Notiogogenin

2.Flavones glycosides – Kaempferol 3-

rhamnoside and tribuloside

3. Trace alkaloids and Fixed oils

Page 29: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses -

Page 30: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chirata Synonym – Bitter stick , Indian gentian

Hindi – Chirayata

Sanskrit- Kirata-tikta

Kannada – Kirata kaddi

Malayalam- Kiriyattu

Biological source:

It consists of dried entire plant of Swertia chirata.

Family: Gentianaceae

Page 31: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 32: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents

It contains bitter glycosides – Gentiopicrin,

Chiratin, Ophelic acid, Amarogentin, Swerthin.

Xanthone derivatives- Chiratol, Swertianin,

Mangiferin

Triterpenoids – Masilinic acid its trisaccaride

esters

Alkaloids – Gentianine, Gentiocrucine

Page 33: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses -

Bitter tonic

Stomachic

Febrifuge

Laxative

Liver disorders

Anemia

Skin diseases

Page 34: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Karaveera

Synonyms – Indian oleander

Sanskrit – Karavira

Hindi – Kaner

Kannada – Kanagile

Malayalam – Arali

Biological source – It consists of the dried aerial

parts of the plant Nerium indicum

Family – Apocyanaceae

Page 35: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 36: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents -

It contains Toxic principles Neriodorin and

Karabin (These are powerful cardiac poisons

similar to the constituents of digitalis ) .It also

contains Odorin

Uses –

1.Used as a Cardiotonic drug

2.Used in Heart diseases

Page 37: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Tylophora Biological source –

It consists of dried leaves of Tylophora indicia

(Tylophora asthamatica)

Family - Asclepiadaceae

Chemical constituents – It contains

Phenanthroindolizidine alkaloids – Tylophorine,

tylophoranine, tylophoranidine

Page 38: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 39: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

It also contains Cetyl alcohol , phytosterol

Wax, resin, pigments tannins , glucose,

quercetin, kaempferol and tyloindane.

Uses-

1. The dried leaves are emetic , diaphoretic, and

expectorant.

2. It is useful in dysentery, catarrh

Page 40: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

3.The roots possesses stimulant, emetic,

expectorant, stomachic, diaphoretic properties

and used in the treatment of asthama,

bronchitis, diarrhoea.

4. They are recommended in rheumatism and

gout pain.

Page 41: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Rasna Synonyms – Galanga, Chinese ginger,

Rasagadde (Kannada), Sugandha (Hindi)

Biological source –

Rasna consists of the dried rhizome of Alpinia

officinarum

Family - Zingiberaceae

Page 42: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical constituents-

It contains –

1.Volatile oil – 1,8 cineole, alpha and β-

pinene, camphene

2.Flavonoids – Kaempferrol, galangin and

alpinin

3. Tannins – Phobaphenes

4.Resin- Galangol

5.Starch

Page 43: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses-

1. Used in Rheumatism

2. Used as Stomachic

3. Used as Carminative

4.Used as Stimulant

5. Used as an Aphrodisiac

6. Antibacterial and antifungal properties

7. Flavouring agent

8. Tonic and spice

Page 44: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Malkangni Biological source –

It consists of the dried seeds of the plant

Celastrus paniculatus ( Celastrus montana)

Family – Celastraceae

Chemical constituents –

1.Fatty oil – Palmatic acid, oleic acid, linolenic

acid

Page 45: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

2.Sesquiterpene alkaloids – Celapanin,

celapanigin

3. Sesquiterpene polyesters - Malkangunin

Uses –

1.Used as emetic, febrifuge, diaphoretic,

nervine properties

2. Used for the sharpening the memory

Page 46: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

3. Used to cure ulcers, rheumatism, gout

4.Used in the traditional system of medicine

as a sedative.

Page 47: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Bhilva Biological source – It consists of the dried

fruits of the plant Semicarpus anacardium

Family - Anacariaceae

Chemical constituents –

It contains anacardic acid, anacardiol,

semicarpol, volatile oil - cardol

Page 48: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses -

Used as tonic, syphilis, epilepsy, anti-

inflammatory, rheumatism, asthama,

bronchitis, piles, skin diseases, worms

Page 49: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Kalijira Biological source – It consists of the dried whole plant of Veronia

anthelminticum Family – Asteraceae Chemical constituents – 1.Flavonoids – 7-o-β-D- glucopyranosyl- alpha-

D- xylopyranosides 2. It also contains sterols like palmatic acid,lauric

acid, carbohydrates, lipids etc

Page 50: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses- Anthelmintic

Tonic

Stomachic

Diuretic

Antiseptic

Asthama

Page 51: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Shankapushipi Synonyms – Vishnukranti

Biological source – It consists of the dried

plant of Convolvulus pluricaulis (Convolvulus

microphyllus) and Evolvulus asinoides

(Convolvulus asinoides )

Family : Convolvulaceae

Page 52: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore
Page 53: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Chemical Constituents-

It contains glycosides, coumarins, flavonoids

and alkaloids.

o Shankhapushpine (the alkaloid) has been

identified as active principle. Others like

Convolvine, Convolamine etc

o β- sitosterol glycoside

o Hydroxy Cinnamic acid

Page 54: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Uses- Used as a brain tonic, febrifuge.

It is used as a psycho stimulant and

tranquilizer. It is reported to reduce mental

tension(Hyper tension).

Page 55: Traditional drugs by Dr.U.Srinivasa, Professor and Head, Srinivas college of pharmacy, Mangalore

Talk doesn’t cook rice”. - Chinese

Proverb

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