Today’s Agenda w Objective 13-16 notes w Practice w Objective 17- 18 notes.

Today’s Agenda

Objective 13-16 notes Practice Objective 17- 18 notes

Immune System Day 6

A single event can awaken within us a stranger totally

unknown to us.Saint-Exupery

Antibody structure

Antibodies

2 heavy chains (450 amino acids)

2 light chains (220 amino acids

Connected by a (S-S) disulfide bridge.

The whole protein has 1340 amino acids.

Objective 14

Active immunity is acquired during an infection or from a vaccination.

Obj.14 continued

Passive immunity is given when a donor’s antibodies are injected into the blood-stream or from mother.

Obj. 15 5 Classes of Antibodies

IgA (immunoglobulin A) IgG (these all differ by IgM structure and function) IgD IgE

Obj. 16 Function of Antibodies

Complement fixation Antigen neutralization Precipitation Agglutination

Neutralization by Antibodies

Agglutination by Antibodies

Precipitation of Dissolved Antigens by Antibodies

Activation of Complement By Antibodies

Practice

Objective 17: Clonal Selection of T cells T cell growth is stimulated by

the protein displayed on the surface of the macrophage.

Some become active killers others become memory T cells.

Obj. 18: Roll of T Cells Cytotoxic T cells attack and

lyse infected cells. Helper T cells release

interleukin. Suppressor T stop immune

response

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36698 Laser Disk 11