TITAX AMI Trial Y. Giraud-Sauveur on behalf of P.Karjalainen, MD, PhD : Principal Investigator BCIS 2009 London, UK A Prospective, Randomized Trial Comparing TITAN-2 ® Stent and TAXUS- Liberte ® Stent in Acute Myocardial Infarction 24-months Clinical Follow-Up
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TITAX AMI Trial Y. Giraud-Sauveur on behalf of P.Karjalainen, MD, PhD : Principal Investigator BCIS 2009 London, UK A Prospective, Randomized Trial Comparing.
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TITAX AMI Trial
Y. Giraud-Sauveur on behalf of
P.Karjalainen, MD, PhD : Principal Investigator
BCIS 2009 London, UK
A Prospective, Randomized Trial Comparing TITAN-2® Stent and TAXUS-Liberte® Stent in
Acute Myocardial Infarction
24-months Clinical Follow-Up
TITAX AMI trial
P Karjalainen, MD, PhDJuhani Airaksinen, Antti Ylitalo, Matti Niemelä,
- Stabilizes microtubules to inhibit smooth muscle cell migration and proliferation
- Stable and durable Translute Polymer * Vascular compatible, biocompatible * Controlled and consistent dose release of paclitaxel
Background: TITAX AMI at 1-YearEurointerv 2008;4:234-241
TCT 2007, Late Breaking Trial
Comparison of titanium-nitride-oxide-coated Comparison of titanium-nitride-oxide-coated TITAN-2TITAN-2®®
Stent to the paclitaxel-eluting Stent to the paclitaxel-eluting TAXUS-LiberteTAXUS-Liberte®® stent stent
resulted in:resulted in:
• Comparable clinical outcome at 1-Year
• Secondly, although the overall risk of stent thrombosis although the overall risk of stent thrombosis was low, it concentrated on the use of TAXUS-Libertewas low, it concentrated on the use of TAXUS-Liberte®® stentstent
• In addition, stent thrombosis occurred in 3 patients after premature discontinuation of clopidogrel.
Participating Centers in Finland
Purpose ofthe TITAX AMI trial
Initiated by the investigators
A Prospective, Multi-center, Randomized Trial that
Compares the Implantation of Titanium-Nitride-Oxide
Coated Stents to Paclitaxel-Eluting Stents for Acute