Product Portfolio Revolutionary • Regenerative • Therapeutic Tissue Source Products Fetuin-A Interleukin 37 Macrophage Colony Stimulating Factor Serpin A4 Syndecan - 4 Bone Morphogenic Protein - 7 Complement Component 5a Fibroblast Growth Factor Platelet Derived Growth Factor - AA Thrombospondin - 2 Adhesion G Protein Collagen 1, 2, 3 Elastin Fibronectin Hyaluronic Acid Cystatin - B Galectin - 9 Granulysin Lipocalin - 2 Intracellular Adhesion Molecule 1 Placenta Placenta Umbilical Cord Umbilical Cord Cytokines ISCT Standards AmnioCyte Amniotic Fluid Allograft AmnioCyte Plus Amniotic Matrix Allograft TM TM TM TM CoreCyte PolyCyte Wharton’s Jelly Allograft Wharton’s Jelly Allograft Mesenchymal Stem Cells (MSC) Biologically Young Source Viable MSC Cell Count Positive Expression of CD73 Positive Expression of CD90 Positive Expression of CD105 Lack Expression of CD14 Lack Expression of CD34 Lack Expression of CD45 Lack Expression of HLA-DR Lack Expression of CD19 Viable MSC: Plastic Adherent Mesenchymal Stem Cell Attributes Predictive Biotech’s products are processed from donated human tissue from full term deliveries in accordance with FDA guidelines. Predictive Biotech’s products are regulated as a human cell, tissue, or cellular or tissue-based products (HCT/P) under 21 CFR Part 1271 and Section 361 of the Public Health Service Act. All of Predictive Biotech’s human cell and tissue products are intended for homologous use. Number of check marks reflect relative factor amounts as compared to other Predictive Biotech products. All data represented on this grid is informed by either or all available literature, external validation and internal testing. Empty data fields indicate quantities either found in trace amounts, or quantities not specified in literature. Citations and references on file with Predictive Biotech. Scaffolding Cytokines Homeostatic Cytokines Growth Factor Cytokines General Cytokines MKT-0025, 28 May 2019