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VERITY (Venous Thromboembolism Registry) Third Annual Report 2005 The VERITY Steering Committee Third Venous Thromboembolism Registry Report 2005
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The VERITY Steering Committee

Jan 03, 2016

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The VERITY Steering Committee. Third Venous Thromboembolism Registry Report 2005. Schematic of the report production process. List of contributors. List of contributors. List of contributors. Example table. Number of risk factors for patients with VTE (n=4,603). Overview. - PowerPoint PPT Presentation
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Page 1: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

The VERITY Steering Committee

Third Venous ThromboembolismRegistry Report

2005

Page 2: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Schematic of the report production process

Page 3: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

List of contributors

Page 4: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

List of contributors

Page 5: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

List of contributors

Page 6: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Example table

Page 7: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of risk factors for patients with VTE (n=4,603)

Page 8: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Overview

Page 9: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Database overview

Page 10: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

The growth of the database (n=27,179)

Page 11: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Data submitted by each centre

Page 12: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of risk factors and diagnosis

Page 13: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of risk factors for patients with VTE (n=4,603)

Page 14: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and the number of risk factors (n=17,175)

Page 15: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age distribution for all patients with VTE (n=27,123)

Page 16: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis over time (n=21,486)

Page 17: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age and gender for patients with VTE

Page 18: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age and gender for patients with VTE (n=6,045)

Page 19: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age and gender for patients with VTE and Cancer (n=799)

Page 20: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Rates of different risk factors in patients who have VTE

Page 21: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Presence of various risk factors and final diagnosis

Page 22: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Task Force of the British Committee for Standards in Haematology13

Page 23: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

D-dimer result and final diagnosis

Page 24: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and D-dimer test (n=16,005)

Page 25: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

D-dimer result, DVT pre-test probability and final diagnosis

Page 26: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis, D-dimer result, D-dimer test and DVT pre-test probability (n=11,585)

Page 27: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Suitability for home treatment1 amongst patients with confirmed DVT (n=5,371)

Page 28: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Reason patients with DVT were deemed unsuitable for home treatment; (patients unsuitable for home treatment with recorded reason n=466)

Page 29: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Duration of LMWH therapy and time to therapeutic INR in patients with DVT; patients receiving both treatments only (n=3,248)

Page 30: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Kaplan-Meier survival curves for patients with confirmed diagnosis of DVT and PE (n=2,224)

Page 31: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Pulmonary embolism

Page 32: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Primary and final diagnosis

Page 33: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Numbers of risk factors

Page 34: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of risk factors according to final diagnosis (n=4,603)

Page 35: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Different risk factors

Page 36: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Presence of selected risk factors for PE and non-PE patients

Page 37: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age and disease

Page 38: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Age distributions according to final diagnosis (n=6,115)

Page 39: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

A. Management of suspected non-massive pulmonary embolism with isotope lung scanning off site only

Page 40: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

B. Management of suspected non-massive pulmonary embolism with isotope lung scanning available on site

Page 41: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

PTP score and final diagnosis

Page 42: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

PTP score distributions for patients with confirmed PE and non-PE patients (n=279 and n=342 respectively)

Page 43: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

PTP score distributions for patients with confirmed PE and non-PE patients (n=279 and n=342 respectively)

Page 44: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

PTP score D-dimer and final diagnosis

Page 45: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis, D-dimer results and PE PTP score for patients with a suspected PE (n=438)

Using <4 and ≥4 to classify the PE PTP score

Page 46: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis, D-dimer results and PE PTP score for patients with a suspected PE (n=438)

Using <2,2-6 and >6 to classify the PE PTP score

Page 47: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Other investigations performed

Page 48: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Investigations performed and diagnosis

Page 49: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Chest x-ray

Page 50: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

The Royal Perth Hospital algorithm

Page 51: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Treatment of patients with PE – location of treatment

Page 52: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Suitability of PE patients for home treatment1 (n=457)

Page 53: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Doses of LMWH

Page 54: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Average number of doses of LMWH for non-PE and PE patients; bars denote standard error

Page 55: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Prediction of the risk of adverse events in PE patients

Page 56: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis

Page 57: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Source of referral for medical inpatients with VTE

Page 58: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Source of referral for surgical inpatients with VTE

Page 59: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Source of referral for patients with a history of surgical inpatient stay and VTE (n=685)

Page 60: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and inpatient history - Overview

Page 61: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and inpatient history

Page 62: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Focus on medical inpatient history

Page 63: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Medical inpatient history for each final diagnosis (n=21,080)

Page 64: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Focus on surgical inpatient history

Page 65: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Surgical inpatient history for each final diagnosis (n=20,996)

Page 66: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Speciality for VTE patients who have recently had surgery (n=685)

Page 67: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis provision for VTE patients (n=3,189)

Page 68: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Source of referral and the use of thromboptophylaxis for VTE patients (n=3,580)

Page 69: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Trends in the use of LMWH as thromboprophylasis for VTE patients (n=730)

Page 70: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis and surgical speciality for VTE patients

Page 71: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis provision and surgical speciality for VTE patients (n=603)

Page 72: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis and inpatient stay

Page 73: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Type of thromboprophylaxis, final diagnosis and inpatient history

Page 74: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis and risk factors in medical inpatients with VTE

Page 75: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and new risk score

Page 76: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis of VTE and weighted risk score (n=5,692)

Page 77: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis and the weighted score

Page 78: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Thromboprophylaxis and weighted risk score (n=4,794)

Page 79: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Kaplan-Meier survival curves for patients with confirmed diagnoses of DVT according to recent medical inpatient history (n=242 and n=1,883 respectively)

Page 80: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Kaplan-Meier survival curves for patients with confirmed diagnoses of DVT according to recent surgical inpatient history (n=266 and n=1,839 respectively)

Page 81: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of referrals over time according to patients’ history and Percentage of patients with confirmed VTE over time according to patients’ history

Page 82: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Number of referrals over time according to patients’ history and Percentage of patients with confirmed VTE over time according to patients’ history

Page 83: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

VTE and Cancer

Page 84: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Cancer rates amongst VTE patients at each hospital

Page 85: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and cancer

Page 86: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Presence of a final diagnosis of VTE in cancer and non-cancer patients

Page 87: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Cancer, age and gender in patients with VTE

Page 88: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Cancer rates broken down by age and gender for patients with VTE (n=5,655)

Page 89: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Specific type of cancer and age for patients with VTE

Page 90: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Specific type of cancer and age for patients with VTE

Page 91: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Cancer rates broken down by age for the most frequently occuring cancers in VERITY amongst patients with VTE (n=5,582)

Page 92: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Specific type of cancer and final diagnosis

Page 93: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Type of cancer and final diagnosis (n=1,205)

Page 94: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

D-dimer and cancer

Page 95: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

D-dimer results in the context of cancer (n=15,240)

Page 96: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Location of treatment

Page 97: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Location of treatment and cancer for VTE patients (n=5,480)

Page 98: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Doses of LMWH

Page 99: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Duration of LMWH therapy and time to therapeutic INR in patients with DVT in the context of cancer; patients receiving both therapies only (n=3,444)

Page 100: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Duration of LMWH therapy in patients with VTE in the context of cancer (n=4,138)

Page 101: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Kaplan-Meier survival curves for patients with confirmed diagnoses of VTE according to the presence of absence of cancer (n=2,224)

Page 102: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Walsgrave hospital: Cancer and medium-term mortality in VTE patients

Page 103: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

VTE and Pregnancy

Page 104: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and pregnancy

Page 105: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and pregnancy (n=12,336)

Page 106: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Risk factors and pregnancy

Page 107: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and pregnancy (n=3,389)

Page 108: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Final diagnosis and selected risk factors amongst pregnant patients

Page 109: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Investigations and pregnancy

Page 110: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Investigations in pregnant patients

Page 111: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Treatment and pregnancy – use of LMWH

Page 112: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

LMWH use and final diagnosis for pregnant patients (n=378)

Page 113: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Doses of LMWH

Page 114: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

LMWH doses and final diagnosis for pregnant patients;bars denote standard errors (n=89 and 50 respectively)

Page 115: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Warfarin therapy and post partum

Page 116: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Warfarin use and final diagnosis for post partum patients (n=425)

Page 117: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Summary of protocol for thromboprophylaxis in women with previous VTE and / or thrombophiliai

Page 118: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

A clinical model for predicting pre-test probability for deep vein thrombosisi

Page 119: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

Variables used to determine a pre-test probability score in patients with suspected pulmonary embolismii

Page 120: The VERITY Steering Committee

VERITY (Venous Thromboembolism Registry) Third Annual Report 2005

A new weighted score to determine the risk of VTEiii