The Platinum Journal COME SCRIVERE UN LAVORO SCIENTIFICO 85° Congresso SIU - Venezia 2012 Review Article: how to summarize the evidence.

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

PRISMA Checklist

17. Selecting the studies (flow diagram)

18. Characteristics of single studies → number, “PICOS”, follow-up, etc.

(narrative synthesis and/or table)

19. Analysis of “bias” risk in each study → randomized (Jadad score, Cochrane risk of bias

tool), observational (Newcastle-Ottawa scale) (table)

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

PRISMA Checklist

20. Results of single studies: a) essential data on all considered “outcomes” for each treatment group (table)

b)estimates of efficacy and confidence intervals (forest plot)

21. Summary of results:meta-analisis with efficacy estimates,

confidence intervals and measures of consistency (narrative sythesis and/or tables)

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

PRISMA Checklist

22. Analysis of bias risk among various studies: “publication bias”, heterogenity (funnel plot)

23. Secondary analises : of senstivity, for sub-groups, etc.

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

“Review Article: how to summarize the evidence”

The Platinum Journal

“COME SCRIVERE UN LAVORO SCIENTIFICO” 85° Congresso SIU -

Venezia 2012

• Clear, objective and balanced presentation

• qualatative and quantatative descriptions

• Critical analysis of controversial points

• Critical analysis of the weakneses of the included studies

How to summarize the results?

“Review Article: how to summarize the evidence”