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The Nuts and Bolts of Lyme Disease Prevention Laura Badeski Oral Vaccinations of Sciurus carolinensis to Reduce the Prevalence of Lyme borreliolis
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The Nuts and Bolts of Lyme Disease Prevention

Apr 14, 2017

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Laura Badeski
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Page 1: The Nuts and Bolts of Lyme Disease Prevention

The Nuts and Bolts of Lyme Disease PreventionLaura Badeski

Oral Vaccinations of Sciurus carolinensis to

Reduce the Prevalence of Lyme borreliolis

Page 2: The Nuts and Bolts of Lyme Disease Prevention

Vector-Borne DiseaseSpread by Borrelia burgdoferi

Lyme Disease

Page 3: The Nuts and Bolts of Lyme Disease Prevention

Transmission Cycle

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Lyme Disease Prevention

Protective clothing

Reduce host populations

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Lyme Disease Prevention

Apply acaracides on hosts

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Developed by SmithKline BeechamStimulates antibodies against OspA76% effective

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LYMErix Vaccine

Vaccine available 1998-2002Speculated to cause arthritis

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OspA to be used as an ecologicalprevention method

Theory

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Recycles past researchRelatively low-risk

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Objectives

Determine efficacy of OspA vaccineReduce B. burdorferi in Eastern Grey squirrels & ticksDecrease Lyme disease prevalence

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White-footed mice vs.Eastern grey squirrels

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Decrease B. burgdorferiDecrease Lyme disease

Hypothesis

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Methods

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Methods

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Methods

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Methods

Lyme disease prevalence survey

Drag sampling

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Page 19: The Nuts and Bolts of Lyme Disease Prevention

Significance

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Significance