The New Aldrich Sure/Seal ™ System The Ideal Solution for Anhydrous Solvents and Air-Sensitive Reagents
The New Aldrich Sure/Seal™ System
The Ideal Solution for Anhydrous Solvents and Air-Sensitive Reagents
sigma-aldrich.com ORDER: 800-325-3010 TECHNICAL SERVICE: 800-325-5832
As the leader in air-sensitive chemistry, Aldrich offers the largest breadth of anhydrous solvents and air-sensitive reagents to the research market. Our original Aldrich Sure/Seal system effectively maintained the quality of these products and aided in their use. Now, we’re upgrading this system with several notable improvements!
The New Aldrich Sure/Seal™ System
Unpunctured 4 PuncturesUnpunctured 4 Punctures
New Aldrich Sure/Seal System Competitor A System
New Crimp Cap Design• Increased puncture area by 4x to accommodate multiple punctures
•Crimpcaphelpsmaintainproductqualityby providing an air-tight system
New Plug Style •Maximizessurfaceareacontactwiththebottleto preventmoistureandoxygenentry
•Morethan50%thickerthancompetingbrands
New Elastomer Liner • Providesoutstanding resealing properties
• Secondaryresinlayerensuresresistancetochemicals
• Outperformscompetingsealswithrespecttomoistureuptake
Previous Aldrich Sure/SealNew Aldrich Sure/Seal
New Plug Style Elastomer Liner
N,N-Dimethylformamide Dimethyl sulfoxide
Methanol Acetonitrile
Diethyl etherA five-week Karl Fischer (KF) analysis study was conducted to determine the effectiveness of the liner’s seal and closure designs,utilizingacoulometrictitrationmethodtomeasurethe rate of moisture uptake.
Solvents Average Weekly Moisture Gain (5 weeks) Aldrich Sure/Seal Competitor A
Chloroform ~ 1.1 ppm ~11.6 ppmDichloromethane ~ 2.2 ppm ~ 14.5 ppm1,4-Dioxane ~ 4.2 ppm ~ 36.4 ppm
Solvents Average Weekly Moisture Gain (5 weeks) Aldrich Sure/Seal Competitor A
n-Hexane* <1 ppm change <1 ppm changePyridine ~ 5.4 ppm ~45.3 ppmToluene ~ 1.7 ppm ~ 7.3 ppm
Moisture Analysis
*Virtually no change within testing variance.
Theinitialwatercontentwassubtractedfromsuccessivetestingvaluestonormalizetheconcentrationofwaterovertime.
Testing MethodsUsing a dried 18-gauge needle, triplicate sample sets from 100 mL bottles received four new punctures per liner each week (5 weeks total) throughout the test schedule for a total of 20 punctures per liner. At the end of each interval, the overcaps were secured by torqu-ing the cap using a force of 40 in-lbs. Throughout the study, both the new Aldrich Sure/Seal System and Competitor A's System were keptunderthesametypicallaboratorystorageconditions(averagetemperature~18˚C(+/-2.7˚C),relativehumidity~39%(+/-4.6%)).
Additional Test Solvents
Aldrich Sure/Seal Testing Results
0
50
100
150
200
250
300
0 1 2 3 4 5Time (weeks)
Moi
stur
e G
ain
(ppm
)Aldrich Sure/Seal: ~7.9 ppm
Competitor A: ~51.3 ppm
Average Weekly Gain
0
50
100
150
200
250
300
350
400
450
500
0 1 2 3 4 5Time (weeks)
Moi
stur
e G
ain
(ppm
)
Aldrich Sure/Seal: ~8.2 ppmCompetitor A: ~81.9 ppm
Average Weekly Gain
0
50
100
150
200
250
300
350
400
450
500
0 1 2 3 4 5Time (weeks)
Moi
stur
e G
ain
(ppm
) Aldrich Sure/Seal: ~7.0 ppm
Competitor A: ~78.9 ppm
Average Weekly Gain
0
50
100
150
200
250
300
350
400
450
500
0 1 2 3 4 5Time (weeks)
Moi
stur
e G
ain
(ppm
) Aldrich Sure/Seal: ~5.1 ppm
Competitor A: ~52.8 ppm
Average Weekly Gain
0
50
100
150
200
250
300
350
400
450
500
0 1 2 3 4 5Time (weeks)
Moi
stur
e G
ain
(ppm
)
Aldrich Sure/Seal: ~8.3 ppmCompetitor A: ~86.2 ppm
Average Weekly Gain
Comprehensive testing confirms the new Aldrich Sure/Seal outperforms other products on the market by maintaining low water absorption even after multiple punctures.
We're Everywhere There's Science
Oxygen Transmission Rate Analysis OxygenTransmissionRate(OTR)isameasurementoftheamountofO2 allowed to permeate into the bottle over a period of time, and demonstrates the cap and liner’s ability to maintain an airtight seal over time.
OTR evaluation of our new Aldrich Sure/Seal against Competitor A demonstrates that the Aldrich Sure/Seal System facilitates a significantly lower oxygen uptake.
New Sigma-Aldrich Sure/Seal System is the market leader for sustaining product quality.
Oxygen Transmission Rate Comparison
0.0000
0.0500
0.1000
0.1500
0.2000
0.2500
Unpunct Punct
OTR
(cc
O2/p
ack/
day)
Aldrich Sure/Seal
Competitor A
Unpunctured Punctured*
For more information on the new Aldrich Sure/Seal System and related products, visit aldrich.com/sureseal.
OxygenTransmissionRateTestingApparatus
*Linerswerepunctured4timeswithan18-gaugeneedle,andovercapsweretorquedto40inlbs.
Aldrich Sure/Seal System
Aldrich Sure/Seal System Competitor A System
The above photos illustrate the effects of repetitive punctures (4 per week) using a dried 18-gauge needle The Aldrich Sure/Seal System liner was not prone to upward swelling nor did it show evidence of bowing. Competitor A’s liner demonstrated dramaticlinerdamageduringtherepetitivepuncturetestinginboththeTolueneandn-Hexane,howeversignificantwatergainwasnotobservedinthen-Hexanesamples.
The New Aldrich Sure/Seal gives you the assurance of quality and safety!
It is especially important that proper care and dispensing procedures are followed when handling air-sensitive products. Safety is important to Sigma-Aldrich, so to assist in the safe handling and dispensing of our air-sensitive products please consult Technical Bulletin AL-134: Handling Air-sensitive Reagents, on our web site at aldrich.com/technicalbulletins
For more information on how the new Aldrich Sure/Seal can benefit your lab, visit aldrich.com/sureseal. You will also be able to review all testing results and find the products that are now using the new Aldrich Sure/Seal.
Week 4 - 16 punctures Week 6 - 24 puncturesWeek 4 - 16 punctures Week 6 - 24 punctures
Competitor A System
New Sample - 0 punctures Week 2 - 8 puncturesNew Sample - 0 punctures Week 2 - 8 punctures
Liner Integrity AnalysisProduct liners for air-sensitive solvents and reagents should not only seal to retain product quality, but they should consistently maintain form after repeated punctures.
The two studies below show the Aldrich Sure/Seal System and Competitor A’s System for repetitive puncturing when containingTolueneandn-Hexane.
Liner Integrity Testing with Toluene - 5 weeks (20 punctures)
Liner Integrity Testing with n-Hexane
MHT73139-510273
1030
©2010Sigma-AldrichCo.Allrightsreserved.Sure/Seal,SIGMA,SAFC,SIGMA-ALDRICH,ALDRICH,FLUKA,andSUPELCOaretrademarksbelongingtoSigma-AldrichCo.anditsaffiliateSigma-AldrichBiotechnology,L.P.Sigma brand products are sold through Sigma-Aldrich, Inc. Sigma-Aldrich, Inc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publications. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see reverse side of the invoice or packing slip.
Check with your Print Buyer to see if your project is going to be printed on recycled paper or not. If not, please remove the recycle logo and copy.
Order/Customer Service (800) 325-3010 • Fax (800) 325-5052 Technical Service (800) 325-5832 • sigma-aldrich.com/techserviceDevelopment/Custom Manufacturing Inquiries (800) 244-1173Safety-related Information sigma-aldrich.com/safetycenter
Sigma-Aldrich® Worldwide Offices
XXX00000-000000
0000
©2010 Sigma-Aldrich Co. All rights reserved. SIGMA, SAFC, SIGMA-ALDRICH, ALDRICH, FLUKA, and SUPELCO are trademarks belonging to Sigma-Aldrich Co. and its affiliate Sigma-Aldrich Biotechnology, L.P. Sigma brand products are sold through Sigma-Aldrich, Inc. Sigma-Aldrich, Inc. warrants that its products conform to the information contained in this and other Sigma-Aldrich publications. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Please see reverse side of the invoice or packing slip.
World Headquarters3050 Spruce St.
St. Louis, MO 63103(314) 771-5765
sigma-aldrich.com
Accelerating Customers’ Success through Innovation and Leadership in Life Science, High Technology and Service
ArgentinaFree Tel: 0810 888 7446Tel: (+54) 11 4556 1472Fax: (+54) 11 4552 1698
AustraliaFree Tel: 1800 800 097 Free Fax: 1800 800 096Tel: (+61) 2 9841 0555Fax: (+61) 2 9841 0500
AustriaTel: (+43) 1 605 81 10Fax: (+43) 1 605 81 20
BelgiumFree Tel: 0800 14747Free Fax: 0800 14745Tel: (+32) 3 899 13 01Fax: (+32) 3 899 13 11
BrazilFree Tel: 0800 701 7425Tel: (+55) 11 3732 3100Fax: (+55) 11 5522 9895
CanadaFree Tel: 1800 565 1400Free Fax: 1800 265 3858Tel: (+1) 905 829 9500Fax: (+1) 905 829 9292
ChileTel: (+56) 2 495 7395Fax: (+56) 2 495 7396
ChinaFree Tel: 800 819 3336Tel: (+86) 21 6141 5566Fax: (+86) 21 6141 5567
Czech RepublicTel: (+420) 246 003 200Fax: (+420) 246 003 291
DenmarkTel: (+45) 43 56 59 00Fax: (+45) 43 56 59 05
FinlandTel: (+358) 9 350 9250Fax: (+358) 9 350 92555
FranceFree Tel: 0800 211 408Free Fax: 0800 031 052Tel: (+33) 474 82 28 88Fax: (+33) 474 95 68 08
GermanyFree Tel: 0800 51 55 000Free Fax: 0800 64 90 000Tel: (+49) 89 6513 0Fax: (+49) 89 6513 1160
HungaryIngyenes telefonszám: 06 80 355 355Ingyenes fax szám: 06 80 344 344Tel: (+36) 1 235 9063Fax: (+36) 1 269 6470
IndiaTelephoneBangalore: (+91) 80 6621 9400New Delhi: (+91) 11 4358 8000Mumbai: (+91) 22 2570 2364Hyderabad: (+91) 40 4015 5488Kolkata: (+91) 33 4013 8003FaxBangalore: (+91) 80 6621 9550New Delhi: (+91) 11 4358 8001Mumbai: (+91) 22 4087 2364Hyderabad: (+91) 40 4015 5488Kolkata: (+91) 33 4013 8000
IrelandFree Tel: 1800 200 888Free Fax: 1800 600 222Tel: (+353) 402 20370Fax: (+ 353) 402 20375
IsraelFree Tel: 1 800 70 2222Tel: (+972) 8 948 4100Fax: (+972) 8 948 4200
ItalyFree Tel: 800 827 018Tel: (+39) 02 3341 7310Fax: (+39) 02 3801 0737
JapanTel: (+81) 3 5796 7300Fax: (+81) 3 5796 7315
KoreaFree Tel: (+82) 80 023 7111Free Fax: (+82) 80 023 8111Tel: (+82) 31 329 9000Fax: (+82) 31 329 9090
MalaysiaTel: (+60) 3 5635 3321Fax: (+60) 3 5635 4116
MexicoFree Tel: 01 800 007 5300Free Fax: 01 800 712 9920Tel: (+52) 722 276 1600Fax: (+52) 722 276 1601
The NetherlandsFree Tel: 0800 022 9088Free Fax: 0800 022 9089Tel: (+31) 78 620 5411Fax: (+31) 78 620 5421
New ZealandFree Tel: 0800 936 666Free Fax: 0800 937 777Tel: (+61) 2 9841 0555Fax: (+61) 2 9841 0500
NorwayTel: (+47) 23 17 60 00Fax: (+47) 23 17 60 10
PolandTel: (+48) 61 829 01 00Fax: (+48) 61 829 01 20
PortugalFree Tel: 800 202 180Free Fax: 800 202 178Tel: (+351) 21 924 2555Fax: (+351) 21 924 2610
RussiaTel: (+7) 495 621 5828Fax: (+7) 495 621 6037
SingaporeTel: (+65) 6779 1200Fax: (+65) 6779 1822
SlovakiaTel: (+421) 255 571 562Fax: (+421) 255 571 564
South AfricaFree Tel: 0800 1100 75Free Fax: 0800 1100 79Tel: (+27) 11 979 1188Fax: (+27) 11 979 1119
SpainFree Tel: 900 101 376Free Fax: 900 102 028Tel: (+34) 91 661 99 77Fax: (+34) 91 661 96 42
SwedenTel: (+46) 8 742 4200Fax: (+46) 8 742 4243
SwitzerlandFree Tel: 0800 80 00 80Free Fax: 0800 80 00 81Tel: (+41) 81 755 2828Fax: (+41) 81 755 2815
United KingdomFree Tel: 0800 717 181Free Fax: 0800 378 785Tel: (+44) 1747 833 000Fax: (+44) 1747 833 313
United StatesToll-Free: 800 325 3010Toll-Free Fax: 800 325 5052Tel: (+1) 314 771 5765Fax: (+1) 314 771 5757
VietnamTel: (+84) 3516 2810Fax: (+84) 6258 4238
Internetsigma-aldrich.com