The Gut-Brain Matrix, Reprogramming Health for Kids, Moms, and Other Superheroes Zach Bush, MD Internal Medicine, Endocrinology and Metabolism Founder, Director of Clinical Affairs Revolution Health Center Charlottesville, VA Founder, CEO Biomic Sciences
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The Gut-Brain Matrix, Reprogramming Health for Kids, Moms ... · Bacterial Metabolites: Carbon-Based Redox System • Each bacterial species (30,000 species) creates a unique subset
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Biodiversity = fluid communication = strong defense
Functional Gut Barrier
www.restore4life.com
Gliadin (Gluten)
Tight Junction ImagingCONTROL Gliadin in 1 slice of pizza
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Glyphosate
Tight Junction ImagingCONTROL GLYPHOSATE 10 PPM
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Bacterial communication impacts
tight junction functionT
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CONTROL GLIADIN
GLIADIAN and RESTORE RESTORE ww
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CONTROL GLYPHOSATE
GLYPHOSATE and RESTORE RESTORE
GLUTENToxic Peptides
CXCR3
InflammationZONULIN
ENZ
TJ breakdown
Leaky Gut/Brain Leak GutGLYPHOSATE
BACTERIAL/YEAST
OVERGROWTH
Enzymes
Chronic Inflammation
Leaky Gut/Brain
Leaky Gut - Leaky Brain
Inflammation Cascade from birth to death
Colic
Sensory-Processing Defects
Attention Deficit
Anxiety Disorders
Major Depression
Disordered Sleep
Insulin Resistance
Infertility
Diabetes
Vascular Disease
Cancer
Dementia
US Ranks 49th in Health Outcomes
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Gut/Brain Injury
What can we do about it?
• Tight junction firewall up and running
• Direct toxin antidote – glyphosate, gluten, pharmacy
• Promote eco-diversity in the gut and beyond
• Increase enzyme breakdown of toxins
• Increase bio-availability of food nutrients
Maximize the Biome:
Get out in nature – breathe biodiversity
Grow your own food
Eat from the bottom of the food chain
Stop dairy (high glyphosate, highly acidic)
Wild Fermented foods:
miso soup, sauerkraut, etc.
Gut/Brain Communication Supplement:
What’s in Restore?• Raw ingredients include Carbon-based redox
molecules from fossil soil in the USA. This inert raw material is shipped to VA where we put the substrate through a redox process to achieve the safety and biologic efficacy of the finished product
• Trace micronutrients – minerals and amino acids with concentration profiles similar to that of a sweet potato skin.
• Unprecedented results in cellular safety studies– Gold-standard Renal Tubule Toxicity studies – No LD50,
extends life of cell lines at every concentration
– Even at 100% concentrations renal and hepatocyte studies show zero toxicity, instead at every concentration Restore increases longevity/decreases apoptosis rates
Restore Logistics
• For very sensitive individuals:
– 2-5 drops by mouth – plain or
with non-chlorinated water/juice
– Slowly increase to 1 TSP – 1 TBL three times/day
• Reduce or stop probiotics and digestive enzymes to
speed recovery of natural gut biome diversity and
healthy digestive processes
• No drug-drug interactions
Intelligent membranes,
What to expect• Bowel changes – formed stools, more bulk
References1. Centers for Disease Control and Prevention (CDC), Key Findings: Trends in the
Parent-Report of Health Care Provider-Diagnosis and Medication Treatment for ADHD: United States, 2003-2011 the National Survey of Children's Health (NSCH)
2. Ellwood P, Williams H, Aït-Khaled N, Björkstén B, Robertson C, ISAAC Phase III Study Group. Translation of questions: The International Study of Asthma and Allergies in Childhood (ISAAC) experience. Int J Tuberc Lung Dis. September 2009; 13(9): 1174-1182
3. Massey JT, Moore TF, Parsons VL, Tadros W. Design and estimation for the National Health Interview Survey, 1985–1994. National Center for Health Statistics. Vital Health Stat 1989;2(110)
4. Botman SL, Moore TF, Moriarity CL, Parsons VL. Design and estimation for the National Health Interview Survey, 1995–2004. National Center for Health Statistics. Vital Health Stat 2000;2(130)
5. Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014. Atlanta, GA: US Department of Health and Human Services; 2014
References6. Janeway, CA Jr.; et al. (2001). "The mucosal immune system". Immunobiology. New
York: Garland Science. 10-13
7. Salminen S, Bouley C, Boutron-Ruault MC, et al. (1998). "Functional food science and gastrointestinal physiology and function". British Journal of Nutrition 80 (S1): S147–S171
8. Moriame G; et al. Viral Suppression and Immune Restoration in the Gastrointestinal Mucosa of HIV Type 1-Infected Patients Initiating Therapy during Primary or Chronic Infection Journal of Virology, August 2006, p. 8236-8247, Vol. 80, No. 16
9. Abbas A.B.; Lichtman A.H. (2009). "Ch.2 Innate Immunity". In Saunders (Elsevier). Basic Immunology. Functions and disorders of the immune system (3rd ed.)
10. Eming, S. A.; Krieg, T.; Davidson, J. M. (2007). "Inflammation in wound repair: molecular and cellular mechanisms". Journal of Investigative Dermatology 127 (3): 514–525
11. Van Dorpe, S; et al. (2012). "Brainpeps: The blood–brain barrier peptide database". Brain structure & function 217 (3): 687–718
12. Schneider, Stefan W.; et al. (March 2004). "Glioblastoma cells release factors that disrupt blood–brain barrier features". Acta Neuropathologica 107 (3): 272–276
References13. H Chen; EE Konofagou. Journal of Cerebral Blood Flow &
Metabolism (2014) 34, 1197–1204
14. H Matsui ; et al. (2011). The pathophysiology of non-steroidal anti-inflammatory drug (NSAID)-induced mucosal injuries in stomach and small intestine J Clin Biochem Nutr. 2011 Mar; 48(2): 107–111
15. Eadon MT; et al. Endotoxemia alters tight junction gene and protein expression in the kidney (2012). Am J Physiol Renal Physiol. 2012 Sep 15; 303(6): F821–F830