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The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman School of Medicine at the University of Pennsylvania Control #: 1751, Poster #: EE-12
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The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Dec 19, 2015

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Page 1: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

The “Guitar Pick” Sign: An expanding repertoire of

orbital pathology

Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD

Department of RadiologyPerelman School of Medicine at the University of Pennsylvania

Control #: 1751, Poster #: EE-12

Page 2: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Disclosures

• Vincent Dam, MD: No disclosures• Joel Stein, MD, PhD: No disclosures• Suyash Mohan, MD: No disclosures

Page 3: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Purpose

• Posterior globe tenting, the “guitar pick” sign, has been associated with acute and often permanent visual impairment.

• The finding is usually seen in the context of orbital trauma and other acute inflammatory pathologies.

Page 4: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Guitar pick

Axial image of an orbital CT in a patient with ocular trauma and left retrobulbar hemorrhage (not shown) with posterior tenting of the left globe.

Page 5: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

• Few cases to date have been reported in association with progressive infiltrating neoplasm.

• Our case serves to expand the clinical context in which the “guitar pick” sign can be seen.

Purpose

Page 6: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Case Report

• A 61-year-old man with locally advanced sinonasal adenoid cystic carcinoma and resultant left eye blindness presented to outpatient clinic with acute right eye blindness of 12 hours duration.

• The patient was transferred to the emergency department where an unenhanced maxillofacial CT was obtained followed by an MRI.

Page 7: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

11/2014

9/2014

Axial (a) & coronal (b) maxillofacial CT demonstrate extensive infiltrating neoplasm involving the sinonasal cavity with bilateral intraorbital extension (yellow arrows) and resultant bilateral "guitar pick" signs (red arrows).

Comparison to prior sinus CT from 9/2014, axial and coronal planes (c & d), demonstrates 11/2014 findings are new and likely correspond to acute symptomatology.

a b

c d

Page 8: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

MRI orbits: Axial & coronal post contrast T1 weighted images corroborate CT findings with extensive infiltrating neoplasm involving the sinonasal cavity with bilateral intraorbital extension (yellow arrows).

Notice, “guitar pick” signs are manifested in the bilateral globes, more conspicuous on the left (red arrows).

11/2014

Page 9: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Treatment & Follow-up

• Based on the imaging findings, the patient was admitted and given a course of high dose corticosteroids as well as targeted radiation. Right eye vision returned after treatment.

• MRI of the orbits 1 month later demonstrated improved left and resolution of right posterior orbital tenting.

Page 10: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

11/2014

12/2014

Follow up axial (a) & coronal (b) post contrast T1 weighted MRI shows marked decrease in tumor extent with corresponding resolution of bilateral posterior globe tenting.

This is compared to the MRI obtained at the time of the patient’s acute presentation (c & d).

a b

c d

Page 11: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

Summary

In addition to prior reports, the guitar pick sign can be seen with infiltrative neoplasms on both CT and MR imaging modalities and corresponds to acute visual impairment.

Prompt medical intervention is essential and can prevent permanent visual damage.

Page 12: The “Guitar Pick” Sign: An expanding repertoire of orbital pathology Vincent Dam MD, Joel Stein MD, PhD, Suyash Mohan MD Department of Radiology Perelman.

References

• Dalley RW, Robertson WD, Rootman J. Globe tenting: a sign of increased orbital tension. AJNR Am J Neuroradiol 1989:10(1):181-6.

• Hrach CJ, Quint DJ. Globe tenting as a result of head trauma. AJNR Am J Neuroradiol 1997:18(5):980-2.

• Theoret J, Sanz GE, Matero D, et al. The “guitar pick” sign: a novel sign of retrobulbar hemorrhage. CJEM Can J Emerg Med Care 2011:13(3):162-4.