The EUnetHTA Planned and Ongoing Projects Database: Content and Use. Marisa Warmuth.

EUnetHTA | European network for Health Technology Assessment | www.eunethta.eu Joint Action 2010–2012EUnetHTA Joint Action 2010–2012 | www.eunethta.eu

EUnetHTA POP db The EUnetHTA Planned and Ongoing Projects Database: Content and Use

Marisa Warmuth (LBI-HTA) on behalf of Claudia Wild, Gerda Hinterreiter, Judit Erdös (LBI-HTA), Patrice

X. Chalon (KCE) and Peter Krämer (DIMDI)

9th HTAi Annual Meeting Bilbao: 27 June 2012

EUnetHTA | European network for Health Technology Assessment | www.eunethta.eu Joint Action 2010–2012

Agenda

• Content:– What is the POP

database? – POP statistics– Alert topics

• Use:– Collaborations– Challenges

2


What is the POP database?

• online database • hosts descriptions of planned and

ongoing projects of EUnetHTA JA partners

• provides a matching system helping to identify similar projects and therefore support collaboration

3


Current POP db content

1,142 projects

• from 42 EUnetHTA partners • from 24 countries

4


Alert topics: Identical drug AND indication

Agencies Drug Indication

5 Arbiraterone acetate Prostate cancer

5 Eribulin Metastatic breast cancer

4 Apixaban Venous thromboembolism

4 Boceprevir Chronic hepatits C

4 Fingolimod Multiple sclerosis

4 Omalizumab Persistent allergic asthma

4 Rivaroxaban Acute coronary syndrome

4 Rivaroxaban Venous thromboembolism

3 Everolimus Breast cancer

5


Alert topics: Identical new technologies

Agencies Technology/ Intervention/ Medical device

7 Transcatheter aortic valve implantation (TAVI)

6 Colorectal cancer screening programmes

5 HPV tests in cervical cancer screening

5 Renal artery ablation

4 Refractive eye surgery

4 Wound healing

4 HPV vaccine

6


Collaboration thanks to POP?

76%

18%6%

noyes, but no collaboration was startedyes, and a collaboration was started

53%

24%

24%

no

yes, but no collaboration was started

yes, and a collaboration was started

No contact because:• No response from the contacted person• Too vague description in POP different scope• Different timeframe

Has your agency been contacted by partners?

Has your agency contacted other partners?


Collaborations by LBI-HTA

9 joint assessments in 2.5 yrs: •7 onco-drugs:

– Cabazitaxel/Jevtana– Dasatinib/Sprycel– Eribulin/Halaven– Abiraterone acetate/Zytiga

•1 ophthalmologic drug (Anti-VEGF)

•1 high-tech intervention (Selective internal radiation therapy/ SIRT)

8

– Vemurafenib– Axitinib/Inlyta– Lenalidomide (ongoing)


LBI-HTA, AHTAPol &

UVEF (Reg. Veneto):

Eribulin (Halaven®) as third- or late- line monotherapy for advanced/metastatic breast

cancer

July 2011

http://eprints.hta.lbg.ac.at/927


Example: Joint Assessments in Horizon Scanning in Oncology• Process:

– 1. Author (project management)– 2. Author: checks literature selection, inclusion of

trials, data extraction; final internal review of completeness and accuracy of data

• Estimated workload: 2 (max. 3) days for second author

• Working language: English

10


Challenges

• Different scopes• Different timeframes/ time pressure• Confidentiality of information• No HTA-doer• No response of contacted person

11


Future perspectives

The POP database potentially • reduces duplication• increases efficiency• increases output of bi-lingual assessments• increases HTA productivity

12

The EUnetHTA Planned and Ongoing Projects Database: Content and Use. Marisa Warmuth.

Health & Medicine

eunethta joint action

health technology assessment

at927eunethta european

eunethta partners

eunethta pop db

lbihta9 joint assessments

pop database

ongoing projects database