1 The Chemistry The Chemistry The Chemistry The Chemistry of of of of Portia Portia Portia Portia Mahal Mahal Mahal Mahal Sabido,Ph.D Sabido,Ph.D Sabido,Ph.D Sabido,Ph.D. Institute of Chemistry Institute of Chemistry Institute of Chemistry Institute of Chemistry 2/12/2009 2 Pattern 2/12/2009 3 Pattern 2/12/2009 4 Pattern 2/12/2009 5 www.humanchemistry.net/ 2/12/2009 6 January 2008 January 13, 2009
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1
The Chemistry The Chemistry The Chemistry The Chemistry ofofofof
Neuroscience for Kids:http://faculty.washington.edu/chudler/chnt1.html
•Agonist
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Our First Our First Our First Our First Experience Experience Experience Experience of Loveof Loveof Loveof Love
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After This. . .
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Major Endocrine Organs
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Oxytocin• From pituitary gland
• Cyclic Peptide
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+H3N Cys Tyr Ile
GlnS
S AsnCys
Pro Leu Gly C
O
NH2•Cyclic Peptide
Oxytocin
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Associated With:
•uterine contractions during labor in childbirth
+H3N Cys Tyr Ile
GlnS
S AsnCys
Pro Leu Gly C
O
NH2•Cyclic Peptide
Oxytocin
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Associated With:
•uterine contractions during labor in childbirth
+H3N Cys Tyr Ile
GlnS
S AsnCys
Pro Leu Gly C
O
NH2•Cyclic Peptide
Oxytocin
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Medical Drugs
•To induce labor :
–PitocinPitocinPitocinPitocin and SyntocinonSyntocinonSyntocinonSyntocinon
–Oxytocin
•To Suppress Premature Labor
–TractocileTractocileTractocileTractocile
–Antagonist of Antagonist of Antagonist of Antagonist of OxytocinOxytocinOxytocinOxytocin
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Oxytocin
•mother/infant bonding
•"let down" reflex necessary for breastfeeding
• 16th century Italian painting by Solarioentitled “The Virgin with the Green Cushion.”
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The Hug Drug
• A 20 second hug is said to release the love drug Oxytocinthat bonds humans at a chemical level.
msbehaviour.blogspot.com/2007/03/can-oxytocin...
http://www.rkliedtke.de/oxytocin2_us.html
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Low Oxytocin
•Diane Witt, assistant professor of psychology from New York has showed that if you block the natural release of oxytocinin sheep and rats, they reject their own young.
• Conversely, injecting oxytocininto female rats who’ve never had sex, caused them to fawn over another female’s young, nuzzling the pups and protecting them as if they were their own.
• intranasal administration of intranasal administration of intranasal administration of intranasal administration of oxytocinoxytocinoxytocinoxytocin causes a substantial causes a substantial causes a substantial causes a substantial increase in trust among humans, increase in trust among humans, increase in trust among humans, increase in trust among humans, thereby greatly increasing the thereby greatly increasing the thereby greatly increasing the thereby greatly increasing the benefits from social interactionsbenefits from social interactionsbenefits from social interactionsbenefits from social interactions 2/12/2009 42
Oxytocin
•Could it be the cure for Social Phobia?
http://www.onlineweblibrary.com/blog/?p=599
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Pattern
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Stages of Love
•Lust
•Attraction
•Attachment
“Sometimes it’s smooth sailing and sometimes they sink. That’s why they’re called relationSHIPS!” 2/12/2009 46
Stages of Love
•Lust–Erotic Passion
•Attraction–Romantic / Obsessive Love
•Attachment–Commitment
“Sometimes it’s smooth sailing and sometimes they sink. That’s why they’re called relationSHIPS!”
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Lust
• Sexual Desire
• Lust evolved for the purpose of sexual mating
bonchitz.blogspot.com2/12/2009 48
Lust Chemicals
Role in Sex Drive
Estrogen Testosterone
•Female sex hormone
•Male sex hormone
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Major Endocrine Organs
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Lust Chemicals
Role in Sex Drive
Estrogen Testosterone
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Role in Sex Drive
Estrogen Testosterone
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Airport
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Stages of Love
• Lust– Erotic Passion
• Attraction– Romantic / Obsessive Love
• Attachment– Commitment
“Sometimes it’s smooth sailing and sometimes they sink. That’s why they’re called relationSHIPS!” 2/12/2009 54
Attraction Chemicals
In-Love Feeling• elation, intense energy, sleeplessness, craving, loss of
• Studies by researchers at University College London
• Neural circuits associated with the way we assess others are suppressed
• Lower level of serotonin (same as those found in people with obsessive compulsive disorders) possibly explaining why those in love "obsess" about their partner
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When In-Love
•couples in this stage of love focus intently on the relationship and often on little else.
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Stages of Love
•Lust
–Erotic Passion
•Attraction
–Romantic Love
“Sometimes it’s smooth sailing and sometimes they sink. That’s why they’re called relationSHIPS!” 2/12/2009 70
Power of Love
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•Love’s pleasure lasts but a moment; love’s sorrow lasts all through life
•Celestine, French writer of Fables
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Antidepressant
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Stages of Love
•Lust–Erotic Passion
•Attraction–Romantic Love
•Attachment–Commitment
“Sometimes it’s smooth sailing and sometimes they sink. That’s why they’re called relationSHIPS!” 2/12/2009 76
• In 1975, endorphin receptors were discovered by two independent teams of researchers, John Hughes and Hans Kosterlitz in Scottland and Rabi Samantov and Solomon Snyder in the U.S.
• Mishra reported that Sahaja Yoga meditation resulted in a "significant increase" in beta-endorphins between control and meditating subjects
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• Helen Fisher, anthropologist
• “The human body releases the cocktail of love rapture only when certain conditions are met and ... men more readily produce it than women, because of their more visual nature."
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Outline:Today’sTalk
•What is Love?
•Why We Love?
•Our First Look at Love
•Stages of Love
–Chemistry in Each Stage
•What makes us Fall In Love?
•Summary2/12/2009 94
Courtship Ritual
•Means by which selection takes place
•Related to the amount of trouble invested by females and the number of offspring they can produce
Chemistry of Sex by Fabian Dayrit
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Insects
•Only Marginally inconvenienced by fertilization
•Tend not to be too choosy
•Reproduce without too much hassle
Chemistry of Sex by Fabian Dayrit2/12/2009 96
Theory of Evolution
• Holds that species evolve through the survival of genes which bring about more fit individuals
• Way for those who are choosing to sense and determine which partners are best to attract attention and to advertise desirability
•Reveal to each other intimate details about your lives for half an hour.
•Then, stare deeply into each other’s eyes without talking for four minutes
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Staring
• York psychologist, Professor Arthur Arun, has been studying why people fall in love.
• He asked his subjects to carry out the above 3 steps and found that many of his couples felt deeply attracted after the 34 minute experiment. Two of his subjects later got married.
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•A true geisha can stop a man in his tracks with one look
•preferences for those who remind us of our parents (or others close to us through childhood) because of their personality, sense of humor, likes and dislikes, etc
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Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
flickr.com/photos/15257460@N00/2075833778/
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Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
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Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
2/12/2009 107
Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
2/12/2009 108
Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
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2/12/2009 109
Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
2/12/2009 110
Five Love Languages
•Words of Affirmation
•Receiving Gifts
•Acts of Service
•Physical Touch
•Quality Time
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Needs
Her Needs Her Needs Her Needs Her Needs Tend to BeTend to BeTend to BeTend to Be
• Affection
• Conversation
• Honesty and Openess
• Financial Support
• Family Commitment
His Needs His Needs His Needs His Needs Tend to BeTend to BeTend to BeTend to Be
• Sexual Sexual Sexual Sexual FulfillmentFulfillmentFulfillmentFulfillment