The “Central Dogma" of Biology

The “Central Dogma" of Biology(DNA Replication and Protein Synthesis)

Concept 1: Analyzing the events of the cell cycle

Campbell: Ch 12Lab Handout

Concept 1: Analyzing the events of the cell cycleYou must know:The purpose of cell division

The structure of the replicated chromosome

The stages of the cell cycle and mitosis

Try These!What IS a cell?Why does a cell need to divide?What IS DNA?Why does DNA have to replicate?

Cell Division

The structure of the replicated chromosome

Can you find the sister chromatids and the centromere?

The structure of the replicated chromosomeExplain the difference between

the following terms:◦sister chromatids◦homologous chromosomes

The stages of the Cell Cycle

Growth

Growth

The stages of the Cell CycleAt the end of the cell cycle, the

daughter cells will have _______ amount of DNA as the parent cell in G1

The stages of the Cell CycleAt the end of the cell cycle, the

daughter cells will have _______ amount of DNA as the parent cell in G1

THE SAME

The stages of the Cell CycleAt the end of the cell cycle, the

daughter cells will have _______ amount of DNA as the parent cell in G1

THE SAME

Diploid Diploid (2n) (2n) or

Haploid Haploid (n) (n)

Control of Cell Cycle... checkpoints!

If the cell does not “pass” the G1 checkpoint, it will not divide = G0 phase

Control of Cell Cycle... checkpoints!Cells that cannot control their

cycles grow/divide uncontrollably...tumors/cancer

Control of Cell Cycle... checkpoints!Vocabulary: G1/G2/M phase

checkpoints, G1/S/G2/M/G0 phase, density-dependent inhibition, anchorage dependency, transformation, tumor, benign tumor, malignant tumor, metastasis

The Stages of Mitosis

animal cells: cleavage furrow

plant cells: cell plate

Bioflix!

The Stages of MitosisHow is the metaphase stage of

mitosis different from the metaphase stage of meiosis 1?

Single-File!

Let’s look at some cells!Can you find the different stages

of mitosis?

Lab Finish all diagrams, questions, and calculations for next class (pg 29-34)

Next Class...Zooming into DNA structure...

What does it look like? (Ch 16)