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The Case Formulation Approach to Cognitive-behavior Therapy Jacqueline B. Persons, Ph.D. 4th National Congress of the TACBT Istanbul, November 2015 and University of California at Berkeley
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The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

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Page 1: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The Case Formulation Approach to Cognitive-behavior Therapy

Jacqueline B. Persons, Ph.D.4th National Congress of the TACBT

Istanbul, November 2015

and University of California at Berkeley

Page 2: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

With thanks to . . .

• Mehmet Sungur and the TACBT• Ching Yee Tsoi

Page 3: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The clinician’s problem:Providing evidence-based care

for each unique patient

Page 4: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Very little here is original. I am borrowing from….

• Aaron T. Beck• Joseph Wolpe• Ira Turkat, Stephen Haynes• Kuyken, Padesky, & Dudley• Nick Tarrier• Michael Lambert . . .• and many others

Page 5: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Empirically supported treatment protocols (ESTs) are part of the solution

Page 6: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Characteristics of EST protocols

• Target a single disorder• Fixed duration of treatment• Fixed interventions• Fixed order of interventions

Page 7: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

• 18 to 20 sessions

• Interventions target behaviors, automatic thoughts, and schemas, in that order

• Each session follows a fixed structure: check-in, homework review, agenda-setting, etc.

Cognitive Therapy for Depression

Page 8: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Plan for My Talk

• Why are ESTs only part of the solution?• The rest of the solution: A case

formulation approach to cognitive-behavior therapy

• Empirical support for a case formulation approach to CBT

Page 9: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Plan for My Talk

• Why are ESTs only part of the solution?• The rest of the solution: A case

formulation approach to cognitive-behavior therapy

• Empirical support for a case formulation approach to CBT

Page 10: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Why are ESTs only partof the solution?

Page 11: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Multiple disorders and problems

Page 12: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Unique Needs/Goals: The mother who wanted help using public bathrooms during her child’s

hospital stay

Page 13: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Problem Behaviors Impede Treatment

Page 14: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The EST protocol can’t guide all the decisionsthe clinician must make

Adapted from Kohlenberg, R. J., & Tsai, M. (1991). Functional analytic psychotherapy.

Page 15: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

When patient motivation to change is low, high therapist adherence to CBT for panic is associated with worse outcome

Huppert et al.2006

Page 16: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

No EST is availablefor these disorders and problems

• Most personality disorders• Asperger’s disorder• Many somatization disorders• Dissociative disorders• “I want to get married and have a family.”

Page 17: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

ESTs provide little help with failureWhen the patient does not respond to the

empirically-supported protocol,it is difficult to know what to do next.

Page 18: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Large Proportions of Depressed Patients Who Receive ESTs Do Not Respond

Driessen et al., 2013 CBT 37%Psychodynamic 42%

Luty et al., 2007 Interpersonal Therapy 59%CBT 49%

DeRubeis et al., 2005 42% CBT42% Antidepressant Medication

Page 19: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Most change in CBT for depressionhappens early in treatment

Ilardi & Craighead, 1994, Clin Psychol Sci Prac 1:138-156.

Page 20: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

It may be unwise to complete the protocol treatment when the patient does not show an

early response.

Page 21: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Why are ESTs only partof the solution?

Multiple disorders and problemsUnique needs and goalsProblem behaviors impede treatmentNo ESTs for many disordersESTs provide little help with failure

Page 22: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Plan for My Talk

• Why are ESTs only part of the solution?• The rest of the solution: A case

formulation approach to cognitive-behavior therapy

• Empirical support for a case formulation approach to CBT

Page 23: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

A case formulation approach to cognitive-behavior therapy

Assessment

CaseFormulation(hypothesis)

Intervention

Progress Monitoring

Page 24: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Elements of a case formulation Approach

• Assess to develop a formulation• Use the formulation to guide

intervention and solve problems• Monitor progress at every session

Page 25: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Definition of Formulation

A formulation is a hypothesis about the

psychological mechanisms that cause and

maintain a patient’s problems.

Page 26: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

“I’m a loser.”“If I am not perfect,

I’ll be rejected.”

social anxiety and isolation

“If I say hi she’llthink I’m a nerd.”

procrastinationat work

“I’ll make a mistakeand get fired.”

depressionlack of enjoymentguilt“I’m a loser.”self-criticism

Page 27: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

To develop an individualized case formulation

• Begin with an evidence-based formulation (e.g., Beck’s cognitive theory of depression)

• Individualize• Expand to account for all of the

patient’s symptoms and problems

Page 28: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Beck’s Cognitive Theory of Depression

Behaviors

Automatic Thoughts

Emotions

SchemasEvents

Page 29: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Problem 5

Problem 1 Problem 2 Problem 3

Problem 4

SchemasEvents

BECK’S COGNITIVE MODELOF THE MULTIPLE-PROBLEM CASE

Page 30: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

“I’m a loser.”“If I am not perfect,

I’ll be rejected.”

social isolation“If I say hi she’ll

think I’m a nerd.”

procrastinationat work

“I’ll make a mistakeand get fired.”

depressionlack of enjoymentguilt“I’m a loser.”self-criticism

Page 31: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Treatment Targets identified by Beck’s Cognitive Theory of Depression

Behaviors

Automatic Thoughts

Emotions

SchemasEvents

Page 32: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

“I’m a loser.”If I am not perfect,

I’ll be rejected.”

social isolation“If I say hi she’ll

think I’m a nerd.”

procrastinationat work

“I’ll make a mistakeand get fired.”

depressionlack of enjoymentguilt“I’m a loser.”self-criticism

Page 33: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Select interventions from ESTs and other sources

Page 34: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Monitor progress at every session

0

5

10

15

20

25

30

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Scor

e

Session

Anxiety

Stress

Depression

Page 35: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

A Case Formulation-driven Approach to Cognitive-behavior Therapy

Assessment

CaseFormulation(hypothesis)

Intervention

Progress Monitoring

Page 36: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

How does a case formulation approach address these problems?

Multiple disorders and problemsUnique needs and goalsProblem behaviors impede treatmentNo ESTs for many disordersESTs provide little help with failure

Page 37: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

case formulation-driven CBT can handle all of these problems

Multiple disorders and problems

Page 38: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

“I’m a loser.”“If I am not perfect,

I’ll be rejected.”

social isolation“If I say hi she’ll

think I’m a nerd.”

procrastinationat work

“I’ll make a mistakeand get fired.”

depressionlack of enjoymentguilt“I’m a loser.”self-criticism

Page 39: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Unique Needs/Goals: The mother who wanted help using public bathrooms

during her child’s hospital stay

Page 40: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Problem Behaviors Impede Treatment

Page 41: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Use the case formulation to determine how to respond to this question

Adapted from Kohlenberg, R. J., & Tsai, M. (1991). Functional analytic psychotherapy.

Page 42: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

No ESTs for many disorders

Case Formulation-driven CBT can guide treatment when no

EST exists

• Steve, a young man who had psychogenic vomiting and mental retardation

Page 43: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

I used the OPERANT CONDITIONING model to develop a formulation (functional analysis)

and treatment plan

AAntecedents

BBehavior Consequences

Page 44: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Functional AnalysisAntecedents (A) Behaviors (B)

(actions, thoughts, or emotions)

Consequences (C)

Page 45: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Functional Analysis of Steve’s Vomiting Behavior

Antecedents(A)

Behaviors (B)

Consequences (C)

Boredom

Nothing to do

No meaningful relationships

VomitingFather cleans up vomit, takes patient to hospital and stays there with him for hours.TV, couch, pampering at home.

Page 46: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Treatment of Steve’s Vomiting Behavior Based on the Functional Analysis

Antecedents(A)

Behaviors (B)

Consequences (C)

Day treatment program Vomiting

Clean up own vomit.Father takes to hospital, then leaves.No pampering at home after vomiting.

Page 47: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The case formulation approach offers strategies to

address treatment failure

1. Monitor progress to identify failure early and take action to address it.

2. Consider whether a different formulation might lead to different interventions that might lead to a better outcome

Page 48: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The case formulation approach offers strategies to address

treatment failure

1. Monitor progress to identify failure early and take action to address it.

2. Consider whether a different formulation might lead to different interventions that might lead to a better outcome

Page 49: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Patient with depression and ADHD who does not improve at all during 8 sessions of treatment

Page 50: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Several symptoms of ADHDinterfered with treatment

• Patient was not taking her ADHD medications reliably because she forgot to do it

• Patient was not taking her antidepressant because she forgot to ask her psychiatrist to renew the prescription

• Patient arrived late to therapy sessions because she did not allow sufficient travel time

Page 51: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Aggressive focus on symptoms that interfered with treatment led to some progress

Page 52: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The case formulation approach offers strategies to address

treatment failure

1. Monitor progress to identify failure early and take action to address it.

2. Consider whether a different formulation might lead to different interventions that might lead to a better outcome

Page 53: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

A Case Formulation-driven Approach to Cognitive-behavior Therapy

Assessment

CaseFormulation(hypothesis)

Intervention

Progress Monitoring

Page 54: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Overcoming treatment failure:Mr. “I fear I have cancer”

Persons, J. B., & Mikami, A. Y. (2002). Strategies for handling treatment failure successfully. Psychotherapy: Theory/Research/Practice/Training.

Page 55: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Hypochondriacal episodes during treatment that targeted fear of dying (left of blue line) and fear of humiliation (right)

Page 56: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Thought RecordDate Situation Behavior(s) Emotions Thoughts Coping

Responses

Colleague says, “Oh you’re sick again.”

It could be cancer.

I’ll miss work.

I’ll drop a ball.

I’ll lose my job.

I’ll be humiliated.

Page 57: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

case formulation-driven CBT can handle all of these problems

Multiple disorders and problemsUnique needs and goalsProblem behaviors impede treatmentNo ESTs for many disordersESTs provide little help with failure

Page 58: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

A protocol is like a list of directions, whereas a formulation is like a map (if one route is blocked, the map helps you find others)

Page 59: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Plan for My Talk

• Why are ESTs only part of the solution?• The rest of the solution: A case

formulation approach to cognitive-behavior therapy

• Empirical support for a case formulation approach to CBT

Page 60: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Empirical foundations of a case formulation approach to CBT

• Evidence-based formulations • Outcome of formulation-driven

treatment is generally equal to protocol treatment

• Progress monitoring improves outcomes

See Persons & Hong, in press

Page 61: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Naturalistic case formulation-driven CBT for anxious depressed outpatients produces outcomes

similar to those of RCTs for depression

Persons, Roberts, Zalecki, & Brechwald, 2006, Behaviour Research and Therapy

Page 62: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Pre- and Post-treatment BDI in Formulation-driven and Standardized CBT

for Anxious Depressed Outpatients

Persons et al., BRAT 2006

Page 63: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

Pre- and Post-treatment BDI in Formulation-driven and Standardized CBT

When Initial BDI >20

Persons et al., BRAT, 2006

Page 64: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

The most important data are

progress monitoring data collected from every patient during treatment.

Page 65: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

A Case Formulation-driven Approach to Cognitive-behavior Therapy

Assessment

CaseFormulation(hypothesis)

Intervention

Progress Monitoring

Page 66: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress
Page 67: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

In Conclusion

A case formulation approach to CBT provides the clinician with an evidence-based way to adapt the ESTs to the individual needs of the unique patient.

Page 68: The Case Formulation Approach to Cognitive-behavior Therapy · PDF fileThe Case Formulation Approach to Cognitive-behavior Therapy. Jacqueline B. Persons, Ph.D. 4th National Congress

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