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Ch. 2 Molecular development of Drosophila More molecular development of Drosophila Ch. 7 Plant development ay, 10/9, Please bring a copy of the primary research article you h than one if you haven’t decided) plus your notes on the article. no class – October Vacation More plant development Ch. 8 Mechanisms of morphogenesis More morphogenesis Ch. 10 Cell differentiation Happy Halloween Eve! Stem cells Ch. 11 Organogenesis More Organogenesis NO CLASS Veteran’s Day EXAM 2 Chapters 2, 6, 8, 10 Ch. 12 Development of the nervous system More neural development ew paper is due at the beginning of class on Tuesday, 11/18
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Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Dec 16, 2015

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Page 1: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Th 10/2 Ch. 2 Molecular development of DrosophilaT 10/7 More molecular development of DrosophilaTh 10/9 Ch. 7 Plant developmentOn Thursday, 10/9, Please bring a copy of the primary research article you have selected (or more than one if you haven’t decided) plus your notes on the article. T 10/14 no class – October Vacation Th 10/16 More plant developmentT 10/21 Ch. 8 Mechanisms of morphogenesisTh 10/23 More morphogenesisT 10/28 Ch. 10 Cell differentiationTh 10/30 Happy Halloween Eve! Stem cellsT 11/4 Ch. 11 OrganogenesisTh 11/6 More Organogenesis

11/10 NO CLASS Veteran’s Day T 11/11 EXAM 2 Chapters 2, 6, 8, 10 Th 11/13 Ch. 12 Development of the nervous system T 11/18 More neural developmentYour review paper is due at the beginning of class on Tuesday, 11/18

Page 2: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

From our course web site: “Assignments Explained”

two short writing assignments: Each worth 20 points. At any point during the semester, pick any topic in developmental biology from class, text, web, TV, or anywhere and learn more about it. Keep track of all the sources you use (Wikipedia etc.) to learn more and then write a two page paper along with a bibliography of all your sources and hand it. Write two papers like this during the semester. The purpose is to encourage you to track down more knowledge when you find something interesting. A key challenge in your papers is to explain how each topic is actually a topic in the field of developmental biology and not a different area of biology.

Page 3: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.
Page 4: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Chapter #2

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not in text

Page 6: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Genes to focus on during Drosophila embryogenesis

BicoidHunchbackEven-skippedEngrailedAntennapedia

HedgehogWingless

Gurken

TollDorsalDecapentaplegicShort gastrulation

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Page 8: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

not in text: egg chamber

Page 9: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

2.8 fly A/P axisgene hierarchy

Page 10: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Look at the summary paragraphs and associated flow chartsthroughout Chapter 2:

p. 66 Summary: Early Expression of Zygotic Genes

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2.39 Hh/Wg4 nuclei

Page 12: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

2.41 Hh/Wg feedback loop

Page 13: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.
Page 14: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Box 1E Wnt signal transduction

Page 15: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

2.40 Hh signaling pathway

Page 16: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

2.37 clonesin wing

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2.21 D/V slice

Page 18: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Comparing animals and plants:

Invented multicellularity independently

Some differences:

No germ line cells in plants(plants are easy to clone. No maternal factors???)

No morphogenesis in plants(very simple fate maps)

Plant cells contain plasmodesmata(a type of gap junction between cells)

Page 19: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Comparing animals and plants:

Invented multicellularity independently

Some differences:

No germ line cells in plants(plants are easy to clone. No maternal factors???)

No morphogenesis in plants(very simple fate maps)

Plant cells contain plasmodesmata(a type of gap junction between cells)

7.4 fate map

Page 20: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

7.22 root fates

Page 21: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Comparing animals and plants:

Invented multicellularity independently

Some differences:

No germ line cells in plants(plants are easy to clone. No maternal factors???)

No morphogenesis in plants(very simple fate maps)

Plant cells contain plasmodesmata(a type of gap junction between cells)

Fig. 1.23

Page 22: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Fig. 1.23

FT mRNA is transcribed in leaves and then the mRNAgoes through plasmodesmata on the way to cells in the shoot meristem where it is translated into a transcriptionfactor protein that regulates transcription of genes forflowering.

Fig. 6.35

Page 23: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

Comparing animals and plants:

Invented multicellularity independently

Some similarities:

Totipotency(each cell retains the entire genome)

Stem cells (called initials in plants)

Stem cell niches (called meristems in plants)

Homeotic genes(but the genes are different in plants vs animals)

Page 24: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.

7.10 stem/leaf pattern

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Animal terms = totipotent, pluripotent

Plant term = indeterminant

Page 27: Th10/2 Ch. 2Molecular development of Drosophila T10/7More molecular development of Drosophila Th10/9Ch. 7Plant development On Thursday, 10/9, Please bring.