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January2018
TedW.Simon,Ph.D.,DABT Contact4184JohnstonRoad
email:[email protected] Winston,GAUSA30187
website:http://www.tedsimon-toxicology.com
mobile:+01(770)359-9807
SummaryAwardwinningtoxicologistandscientist.10+years’experienceasatoxicologistemployedbytheEnvironmentalProtectionAgency(EPA).10+yearsconsultingandexpertwitnessexperience.ServedasEPA’sseniortoxicologistinthewastemanagementdivisionworkingonriskandsoilcleanup.Wellpublished,includingauthoroftextbookontoxicologyandenvironmentalriskassessmentandareferenceworkonpesticides.Experiencedexpertwitnessonissuesincludingenvironmentalrisk,Illegaldrugs,pharmaceuticals,alcoholandmarijuana,DUI,accidentalpoisoning,andintellectualproperty.Expertiseintoxicology,riskassessment,mathematicalmodeling,statistics,neuroscience,andenvironmental/ecologicalhealthissues.Interestandexpertiseintheeffectsandtestingofalcohol,marijuanaandpharmaceuticals,perfluorinatedchemicals,arsenic,chromium,benzeneandothersolvents.Extensivenationalandinternationalpublicspeakingexperience.15+yearsteachingexperience.
ProfessionalCertification1994-
DiplomateoftheAmericanBoardofToxicology(DABT)
EmploymentHistory2004-present
Principal,TedSimon,LLC,Winston,GA2006-present
AdjunctProfessor,EnvironmentalHealthScience,CollegeofPublicHealth,Universityof
Georgia,Athens,GA1996-2006
Toxicologist,USEnvironmentalProtectionAgency,Region4,Atlanta,GA2003
Instructor,DepartmentofBiology,GeorgiaStateUniversity,Atlanta,GA2001-present
Instructor,DepartmentofEnvironmentalHealthScience,UniversityofGeorgia,Athens,GA1996
EnvironmentalHealthScientist,AgencyforToxicSubstancesandDiseaseRegistry/Centersfor
DiseaseControl,Atlanta,GA1994-1996
Toxicologist,USEnvironmentalProtectionAgency,Region4,Atlanta,GA1993-1994
ProjectScientist,ManTechEnvironmentalInc.,USEPARegion4,Atlanta,GA1993
AssistantProfessorofBiology,LifeCollege,Marietta,GA1991-1993
GeorgiaStateUniversity,PostdoctoralResearchAssociate,Atlanta,GA1989-1991
EmoryUniversity,PostdoctoralResearchFellow,Atlanta,GA1982-1988
GeorgiaStateUniversity,Research/TeachingAssistant,Atlanta,GA
PublicationsBOOKS •
AndersonSA,SimonTW.(2018)DefendingPesticidesinLitigation2018Edition.ThompsonReuters,ISBN:978-
0-314-84654-9•
SimonT.EnvironmentalRiskAssessment:AToxicologicalApproach.(2014)TextbookforGraduateRisk
AssessmentCourses,CRCPressISBN978-1466598294
PEER-REVIEWED JOURNAL ARTICLES •
BellSM,ChangX,WambaughJF,AllenDG,BartelsM,BrouwerKLR,CaseyWM,ChoksiN,FergusonSS,
FraczkiewiczG,JarabekAM,KeA,LumenA,LynnSG,PainiA,PricePS,RingC,SimonTW,SipesNS,SprankleCS,StricklandJ,TroutmanJ,WetmoreBA,KleinstreuerNC.(2017)Invitrotoinvivoextrapolatinforhighthroughputprioritizationanddecisionmaking.ToxicolInVitro47:213-227.
•
BeckerRA,DreierDA,ManibusanMK,CoxLA,SimonTW,BusJS.(2017)HowWellCanCarcinogenicityBePredictedByHighThroughput“CharacteristicsofCarcinogens”MechanisticData?RegulToxicolPharmacol80:185-196
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TedSimon,Ph.D.,DABT Page2of19
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SimonTW,ZhuY,DoursonML,BeckN.(2016)BayesianMethodsforUncertaintyFactorApplicationforDerivationofReferenceValues.RegulToxicolPharmacol80:9-24.
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BeckNB,BeckerRA,ErraguntlaN,FarlandWH,GrantRL,GrayG,KirmanC,LakindJS,LewisRJ,NanceP,PottengerLH,SantosSL,ShirleyS,SimonT,DoursonML.(2016)Approachesfordescribingandcommunicatingoveralluncertaintyintoxicitycharacterizations:U.S.EnvironmentalProtectionAgency'sIntegratedRiskInformationSystem(IRIS)asacasestudy.EnvironInt89-90:110-128.
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BeckerRT,PatlewiczG,SimonTW,RowlandsJC,BudinskyRA(2015)Theadverseoutcomepathwayforrodentlivertumorpromotionbysustainedactivationofthearylhydrocarbonreceptor.RegulToxicolPharmacol73:172-90.
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SimonTW,BudinskyRA,RowlandsJC.(2015)AModelforArylHydrocarbonReceptor-ActivatedGeneExpressionShowsPotencyandEfficacyChangesandPredictsSquelchingduetoCompetitionforTranscriptionCo-activators.PLOSONE,10(6):e0127952
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BeckerRA,FriedmanKP,SimonTW,MartyMS,PatlewiczG,RowlandsJC.(2014)Anexposure:activityprofilingmethodforinterpretinghigh-throughputscreeningdataforestrogenicactivity-Proofofconcept.RegulToxicolPharmacol71:398-408.
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PatlewiczG,SimonTW,RowlandsJC,BudinskyRA,BeckerRA.(2015)Proposingascientificconfidenceframeworktohelpsupporttheapplicationofadverseoutcomepathwaysforregulatorypurposes.RegulToxicolPharmacol71:463-477.
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SimonTW,SimonsSSJr.,PrestonRJ,BoobisAR,CohenSM,DoerrerNG,Fenner-CrispPA,McMullinT,McQueenCA,RowlandsJC(2014)TheUseofModeofActionInformationinRiskAssessment:QuantitativeKeyEvents/Dose-ResponseFramework(Q-KEDRF)forModelingtheDose-ResponseforKeyEvents.CritRevToxicol44Suppl3:17-43.
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Budinsky,RA,SchrenkD,SimonT,VandenBergM,ReichardJF,SilkworthJB,AylwardLL,BrixA,KaminskiN,PerdewG,StarrTB,WalkerNJ,RowlandsJC(2014)Modeofactionanddose-responseframeworkanalysisforreceptor-mediatedtoxicity:thearylhydrocarbonreceptorasacasestudy.CritRevToxicol44(1):83-119
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PatlewiczG,SimonT,GoyakK,PhillipsRD,RowlandsJC,SeidelSD,BeckerRA.(2013)UseandValidationofHT/HCAssaystosupport21stcenturytoxicityevaluations.RegulToxicolPharmacol65(2):259-68.
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StephensML,AndersenM,BeckerRA,BettsK,BoekleheideK,CarneyE,ChapinR,DevlinD,FitzpatrickS,FowleJR,HarlowP,HartungT,HoffmannS,HolsappleM,JacobsA,JudsonR,NaidenkoO,PastoorT,PatlewiczG,RowanA,SchererR,ShakihR,SimonT,WolfD,ZurloJ.(2013)WorkshopReport:Evidence-basedToxicologyforthe21stCentury:OpportunitiesandChallenges.ALTEX30:74-103.
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PatlewiczG,SimonT,GoyakK,PhillipsRD,Rowlands,JCR,SeidelSandBeckerRA(2013)UseandValidationofHT/HCAssaystoSupport21stCenturyToxicityEvaluations.RegulToxicolPharmacol5:1-7.
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KirmanC,Budinsky,RA,YostL,BakerBF,ZabikJM,RowlandsJC,LongTF,SimonT(2011)DerivationofSoilClean-UpLevelsfor2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD)ToxicityEquivalence(TEQD/F)inSoilThroughDeterministicandProbabilisticRiskAssessmentofExposureandToxicity.HumanandEcologicalRiskAssessment17(1):125-158.
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BudinskyRA,LeClyuseEL,FergusonSS,RowlandsJC,SimonT(2010)HumanandRatPrimaryHepatocyteCYP1A1and1A2Inductionwith2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD),2,3,7,8-Tetrachlorodibenzofuran(TCDF)and2,3,4,7,8-Pentachlorodibenzofuran(4-PeCDF).ToxicolSci118(1):224-235.
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SimonT(2010)JustWhoisatRisk?TheEthicsofEnvironmentalRegulation.HumExpToxicol30(8):795-819.•
SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC(2009)EstimatesofCancerPotencyof2,3,7,8-
Tetrachlorodibenzo(p)dioxinusingLinearandNon-linearDose-ResponseModelingandToxicokinetics.ToxicolSci112(2):490-506.
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SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC,LongT(2008)EstimatesofCancerPotencyFor2,3,4,7,8-PentachlorodibenzofuranUsingBothNonlinearandLinearApproachs.ToxicolSci106(2):519-537.
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TedSimon,Ph.D.,DABT Page3of19
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SimonT,BrittJK,JamesRC(2007)DevelopmentofaNeurotoxicEquivalenceSchemeofRelativePotencyforAssessingtheRiskofPCBMixtures.RegulToxicolPharmacol48:148-170.
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SimonTandManningR(2006)DevelopmentofaReferenceDoseforthePersistentCongenersofWeatheredToxaphenebasedoninvivoandinvitroeffectsRelatedtoTumorPromotion.RegulToxicolPharmacol44:268-281.
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SimonT(2000)InDefenseofRiskAssessment:aReplytotheEnvironmentalJusticeMovement’sCritique.HumanandEcologicalRiskAssessment6(4):556-560.
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EnglehardtJD,SimonT(1999)OrderAmidUncertainty.CivilEngineering,AmericanSocietyofCivilEngineers,69(6):8A-13A.
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SimonT(1999)Two-DimensionalMonteCarloSimulationandBeyond:AComparisonofSeveralProbabilisticRiskAssessmentMethodsappliedtoaSuperfundSite.HumanandEcologicalRiskAssessment5(4):823-843.
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SimonT(1997)CombiningPhysiologicallyBasedPharmacokineticModelingwithMonteCarloSimulationtoDeriveanAcuteInhalationGuidanceValueforTrichloroethylene.RegulToxicolPharmacol26:257-270.
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SimonT,BarnesK(1995)OlfactionandPreySearchinthecarnivorousleech,Haemopismarmorata.JExpBiol199:2041-2051.
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SimonT,DerbyCD(1995)MixtureSuppressionwithinhibitionforbinarymixturesfromwholecellpatchclampstudiesofinsituolfactoryreceptorneuronsofthespinylobster.BrainRes678(1-2):213-224.
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SimonT,Schmidt,J,CalabreseRL(1994)ModulationofHighThresholdTransmissionBetweenHeartInterneuronsoftheMedicinalLeechbyFMRF-NH2.JNeurophysiol71:454-466.
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SimonT,OpdykeCA,CalabreseRL(1992)ModulatoryeffectsofFMRF-NH2ontheoutwardcurrentsandoscillatoryactivityinheartinterneuronsofthemedicinalleech.JNeurosci12(2):525-537.
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SimonT,EdwardsDH(1990)Light-evokedwalkingincrayfish:Behavioralandneuronalresponsestriggeredbythecaudalphotoreceptor.JCompPhysiolA166:745-755
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HersheySJ,SimonT,BasteC(1975)Histochemicallocalizationofcytochromeoxidaseingastricmucosa.JHistochemCytochem4:271-282.
ABSTRACTS •
SimonTW,ZhuY,DoursonML,BeckNB.(2016)BayesianMethodsApplication:ProofofConceptand
Pitfalls.SocietyofToxicologyAnnualMeeting,NewOrleans,LA•
SimonTW,BeckNB(2015)BayesianMethodsforUncertaintyFactor(UF)Application:ProofofConcept.
SocietyofRiskAnalysisAnnualMeeting,T2-A.3,Arlington,VA•
CanadyRA,SimonTW.(2015)DisruptiveArrivalofBigDatatoFoodIntakeAssessment.SocietyofRisk
AnalysisAnnualMeeting,M2-H.1,Arlington,VA•
RuizP,SimonT,MumtazM(2014)InterpretingNHANESBiomonitoringData:Dioxins.Abstract96d,The
Toxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March•
BeckerR,SimonT,Patlewicz,G,KennedyS,FarhatA,BudinskyR.(2014)ImprovingTheDevelopmentOf
AdverseOutcomePathways:LessonsLearnedFromTheAHRRodentLiverTumorandAHRAvianTeratogenicity/EmbryolethalityAOPs.Abstract2253TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March
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SimonT.(2014)EvidentiaryStandardsforNeuroactiveandNeurotoxicDrugTesting(2014)Abstract723,TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March
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BeckerR,PatlewiczG,SimonT,GoyakK,PhillipsR,RowlandsJC,SeidelS.(2013)ValidationofHigh-ThroughputandHigh-Content(HT/HC)AssaystoSupport21stCenturyToxicityEvaluations.Abstract2267.TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume132,Issue1,March
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SimonT,StephensM,YangY,ManningR,RowlandsJC,BudinskyRA(2012)Applyingthe“ScienceandDecisions”ConceptualModels”toDioxin.Abstract133.TheToxicologistCD—AnofficialJournaloftheSocietyofToxicology,Volume126,Issue1,March
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Simon,T,RowlandsJC,BudinskyRA(2011)TheToxicEquivalenceFactorfor2,3,7,8-Tetrachlorodibenzofuran(TCDF):ToxicokineticandToxicodynamicConsiderations.OrganohalogenCompounds73:1003-1006.
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SimonT(2010)UsingHumanInVivoAHRActivationasaFunctionalDoseMetricforRiskAssessmentbasedonChloracne,EffectsinKeratinocytesandBackgroundCYPInduction.OrganohalogenCompounds62:582-585.
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SimonT,BudinskyRA,RowlandsJC,AbelTA(2010)Linearvs.NonlinearExtrapolationforDose-ResponseAssessmentofTCDD.OrganohalogenCompounds72:1418-1421.
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HawsL,TachovskyA,StaskalD,AylwardL,BurkhalterB,UrbanJ,SimonT,HarrisM(2010)AnEvaluationoftheInfluenceofDifferentSoilCleanupLevelsontheConcentrationofDioxin-LikeCompoundsinHumanSerum.OrganohalogenCompounds72:1448-1449.
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HarrisM,TachovskyA,StaskalD,AylwardL,BurkhalterB,SimonT(2010)SerumConcentrationsofDioxin-LikeCompoundsinaPopulationofMidlandMichigan:AnEvaluationoftheImpactofSoilExposures.OrganohalogenCompounds72:1442-1443.
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SimonT,GoodrumPE(2010)AComparisonofThreeDifferentMethodsofChildrens’SoilIngestion.TheToxicologist,#1916
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HawsL,TachovskyA,StaskalD,SimonT,BurkhalterK,HarrisMA(2010)EvaluationoftheImpactofSoilExposurestoDioxin-LikeCompoundsonBodyBurdeninaPopulationinMidland,Michigan.TheToxicologist,#1871
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HarrisMA,TachovskyA,StaskalD,SimonT,BurkhalterK,etal.(2010)AssessmentoftheImpactofVariousSoilCleanupLevelsonSerumConcentrationsofDioxin-LikeCompoundsinHumans.TheToxicologist,#1872
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SimonT(2009)CancerPotencyEstimatesfor2,3,7,8-TCDDdevelopedfromtheNationalToxicologyProgramBioassayResults,TheToxicologist,Program#EA1-2251
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SimonT(2009)WhyHumansareLessSensitivetoPCBsthanRhesusMonkeys,TheToxicologist#EA4-2254•
KirmanC,BudinskyR,YostL,RowlandsC,LongT,SimonT(2008)DevelopmentofaDirectContact
Criterion(DCC)for2,3,7,8-TCDDinSoilUsingDeterministicandProbabilisticMethods.OrganohalogenCompounds70:1204-1207.
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KirmanC.,CrouchE,AylwardL,SimonT,BudinskyR,LandenbergerB,LongT(2007)CancerPotencyEstimateFor2,3,4,7,8-Pentachlorodiobenzo(P)Dioxin(4-PeCDF)TheToxicologist,Program#1561,p323.
BOOK CHAPTERS •
VinasRandSimonTW(2017)RiskAssessmentinthe21stCentury:NewTechnologiesandTechniquesin
HistoryofRiskAssessmentinToxicology,1stEdition,SolBobst,Ed.,AcademicPress,ISBN:9780128095324•
SimonT,EdwardsDH(1990)TheCaudalPhotoreceptor:AMultifunctionalSensoryNeuronmayselectits
OutputsbySpikeFrequency.InFrontiersinCrustaceanNeurobiology,WieseK,KrenzW-D,TautzJ,ReichertH,MulloneyB(eds.)Birkhauser-Verlag,Basel,Boston,Berlin
ISBN:978-3-0348-5691-1
Grants,AwardsandHonors2012-15GrantfromtheDowChemicalCompany.Developmentofamodeloftheeffectsoftheavailabilityof
coregulatorproteinsongenetranscription.2009
HonorableMention,RiskAssessmentSpecialtySectionoftheSocietyofToxicology,bestpaperofthe
year:SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC(2009)EstimatesofCancerPotencyof2,3,7,8-Tetrachlorodibenzo(p)dioxinusingLinearandNon-linearDose-ResponseModelingandToxicokinetics.ToxicologicalSciences112(2),490-506.
2005
RecognitionfromtheSouthWireCompanyforinnovativeapproachestoEnvironmentalCleanup2005
EPABronzeMedalforTestimonyintheNormanMayescaseinKnoxville,TNthatledtoadditionalUST
regulationsbeingpassedbytheStateofTennessee
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TedSimon,Ph.D.,DABT Page5of19
January2018
2005
EPABronzeMedalforDevelopingGuidanceonMonitoringLandUseControls2002
EPAScienceAchievementAwardforProbabilisticRiskAssessmentGuidance1995
EPABronzeMedalforCommendableService;Forleadershipinsettingtheexampleinself-directedwork
teammanagementandinsettingtheexamplein"fast-track"multimediaenvironmentalinvestigationandcleanup
1992
EnvironmentalEducationEnterprisesScholarshipinEnvironmentalScience,"PrinciplesofEnvironmentalDrillingandSampling,"AssociationofEngineeringGeologists,Atlanta,GA
1992
SpecialAwardfromtheVicePresidentforResearch,GeorgiaStateUniversity,"Evolutionofdifferentpreychoiceandfeedingstrategyintworelatedspecies,"$1000
1989
NationalResearchServiceAwardF32NS08394-01A1fromNIH-NINCDS"ModulationofIonicChannelsinanOscillatoryNetwork,EmoryUniversity,$41,000
1989
HonorableMention,DonaldB.LindsleyPrizeinBehavioralNeuroscienceforPh.D.Thesis,HonorableMentionforPh.D.thesis,"TheNeuralBasisofLightEvokedWalkinginCrayfish,"SocietyforNeuroscience
Education1989
Ph.D.Neurobiology&Behavior,GeorgiaStateUniversity,Atlanta,GA1971
B.A.Biology,MiddleburyCollege,Middlebury,VT
ProfessionalMemberships• 2006–
RoundtableofToxicologyConsultants• 1995- SocietyofToxicology• 1997–
SocietyforRiskAnalysis• 1984–1993 SocietyforNeuroscience• 2016-
TheToxicologyForum
InvitedLectures2017
“ScientificIssueswiththe“New”TSCARiskAssessmentProcess,”ACIToxicTortandEnvironmental
LitigationConference,Chicago,IL2016
“BayesianMethodsforApplicationofUncertaintyFactors,”SocietyofToxicologyAnnualMeeting,New
Orleans,LA2016
“QuantitativePredictionofPhenotypicChangefromHighThroughputAssayResults,”EPAWorkshoponIn
VitrotoInVivoExtrapolation,February,ResearchTrianglePark,NC2015
“BayesianMethodsforApplicationofUncertaintyFactors,”SocietyforRiskAnalysisAnnualMeeting,
Arlington,VA2015
“ANewLookatToxicityFactorsforToxaphenerelatedtoFishConsumptionintheGreatLakes,”
PresentationtoTheGreatLakesConsortiumforFishAdvisories2014
“QuantitativeKeyEventRelationshipsintheAdverseOutcomePathway(AOP)forAHR-MediatedRodent
LiverTumorPromotionQuantitativeKeyEventRelationshipsintheAdverseOutcomePathway(AOP)forAHR-MediatedRodentLiverTumorPromotion,”InvitedSpeakeratameetingsponsoredbytheNationalInstituteofEnvironmentalHealthSciencesheldinBethesda,MD
2014
“EvidentiaryStandardsforNeuroactiveandNeurotoxicDrugTesting”InvitedSpeakerinaworkshopatthe2014meetingoftheSocietyofToxicology.
2013
“CurrentOutlookforImprovingUncertaintyandRiskCommunication.”InvitedSpeakeratUnderstandingandCommunicatingUncertaintyinHazardAssessment,aworkshopsponsoredbytheCenterforAdvancingRiskAssessmentScienceandPolicy(ARASP)oftheAmericanChemistryCouncil(ACC).
2013
FourLecturesinGraduateLevelEnvironmentalRiskAssessmentandRiskCommunication,UniversityofGeorgia,Athens,GA,Spring2013
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2012
FourLecturesinGraduateLevelEnvironmentalRiskAssessmentandRiskCommunication,UniversityofGeorgia,Athens,GA,Spring2012
2011
“TheToxicEquivalenceFactorfor2,3,7,8-Tetrachlorodibenzofuran:Chemical-AdjustmentFactorsforAddressingTEFUncertainty.”Dioxin2011,Brussels,Belgium,August23,2011
2010
“Linearvs.NonlinearExtrapolationforDose-ResponseAssessmentofTCDD,”Dioxin2010,SanAntonio,TX,September15
2010
“UsingHumaninvivoAHRActivationasaFunctionalDoseMetricforRiskAssessmentBasedonChloracne,EffectsinKeratinocytesandBackgroundCYPInduction,”Dioxin2010,SanAntonio,TX,September13
2009
“DoseThresholdsinCancerRiskAssessment:Yes,theydoexist.”UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October26
2008
"Toxaphene–HowBadisthisPesticide?"UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October9
2008
"NaggingQuestionsaboutPCBs"UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October7
2008
"ToxicologyofPolychlorinatedBiphenyls(PCBs),"GeorgiaPowerToxicSubstancesControlActTraining,GeorgiaPowerHeadquarters,Atlanta,GA,July24.
2008
“NeurotoxicModesofActionofPolychlorinatedBiphenylsandBrominatedFlameRetardants:ImplicationsforEnvironmentalRegulation”,NationalInstituteofEnvironmentalHealthScience5thPCBWorkshop:NewKnowledgegainedfromoldpollutants,May16-22,IowaCity,IA,invitedbyDr.P.R.S.Kodavanti
2007
“NeurotoxicEquivalenceSchemeofRelativePotencyforAssessingtheRiskofPCBMixtures,”Dioxin2007,Tokyo,Japan,invitedbyDr.P.R.S.KodavantiofEPA,September.
2007
“ProbabilisticRiskAssessmentandExposure,”UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA
2006
“Toxaphene–theWorld’sMostMisunderstoodPesticide,”UniversityofGeorgiaDepartmentofEnvironmentalHealthScienceSeminarSeries,Athens,GA
2005
"RegulatoryPerspectivesonProbabilisticRiskAssessment.”SocietyforRiskAnalysisandInterstateRegulatoryCouncilWorkshop.MichiganStateUniversity,EastLansing,Michigan
2004
“NewDirectionsinEnvironmentalIssues:anEPAPerspective.”PanelDiscussionattheGeorgiaEnvironmentalLawSeminar,SaintSimonsIsland,GA
2003
"ProbabilisticApproachestoDose-ResponseAssessment."LecturetoEPA'sRiskAssessmentForum,Washington,DC
2000
“ProbabilisticRiskAssessment:StepbyStep,”SponsoredbyNIEHS,EPAandtheUniversityofFlorida,SafetyHarbor,FL
1999
“EPA’sNewGuidanceonCitizenInvolvementinSuperfundRiskAssessment–WhatLawyersandRiskProfessionalsNeedtoKnow.”PanelDiscussionattheSocietyofRiskAnalysisAnnualMeeting,Atlanta,GA
1999
“CalculatingCleanupLevelswithMonteCarlo:RegulatoryConcernsandPerspective.”WithinasymposiumorganizedbyScottFerson,SocietyforRiskAnalysisAnnualMeeting,Atlanta,GA
1999
“PracticalIssuesintheUseofProbabilisticRiskAssessmentandItsApplicationtoHazardousWasteSites,”sponsoredbyNIEHS,EPAandtheUniversityofFlorida,Sarasota,FL
1996
"EvaluatingtheRiskofLiverCancerfromOccupationalExposuretoTrichloroethylenewithPBPKModelingandMonteCarloSimulation.”ChemicalIndustryInstituteofToxicology,ResearchTrianglePark,NC
KeyExperienceLITIGATION SUPPORT / WORK FOR LEGAL APPLICATION
2018
ExpertConsultationandDepositionaboutinterpretationofpostmortemdruglevelsinblood
Providedverbalopinionstoattorneys;gavedepositiontestimonytoopposingcounsel.
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2017 ExpertTestimonyonPhosphatidylethanol(PEth)inBlood
Gavetestimony(examinationandcross-examination)inBartowCounty,GAfamilycourttoprovide
contexttoPEthbloodlevelsasamarkerofchronicalcoholconsumption2017
ExpertConsultationaboutalcoholasafactorinamotorvehicledeathinadramshopmatter
Providedconsultationandwroteanexpertreportusingantemortemandpostmortemalcohol
estimationsandtheabilityofserverstorecognizeimpairment/intoxication.2017
ExpertTestimonyabouttheeffectsanddispositionofmarijuanainaWorkman’sCompcase
Underwentexaminationandcross-examinationaboutthesignificanceofmeasurementsofTHCandits
metaboliteTHCCOOHasacausalfactorinatrafficaccident.2017
ExpertTestimonyinaDUIcase
ProvidedtestimonyaboutthevalidityofareadingfromtheAlcometerV-XLandalcohol
pharmacokinetics.2017
ExpertLitigationSupport(ongoing)aboutoccupationalexposuretosolventsataCementPlant
Developedmodelofexposuretosolventvaporsoccurringinatestinglaboratorywithmultiplefume
hoodstoassesstheeffectsofmixedsolventexposureoncognitivedeficitsinaworker.2017
ExpertOpiniononPhosphatidylethanol(PEth)inBlood
Pethconcentrationsprovideameasureoftheamountofchronicalcoholconsumption;providedan
estimateofdailyalcoholusecorrespondingtospecificPethconcentrations.2017
ExpertOpiniononDrugUsebyaTruckDriver
ConsidereddepositionandbloodtestresultstodetermineiftheuseofAdderallwasacontributingfactor
toanaccident.2017 ExpertOpiniononAlcoholBloodTesting
Readmedicalrecordsandbloodtestforalcoholtodetermineifabloodtestabout15hoursafteran
injurywasusefulindeterminingimpairmentatthetimeoftheinjury.2017
ExpertReportonTHCTestResultsinBloodandUrineandCognitive/PsychomotorEffects
Consideredmedicalrecordsanddrugtestresultsfromanemployeeinjuredatworktoconcludewhether
marijuanausemayhavecontributedtotheinjury.2016
ExpertConsultationonChemicalsfoundinFloorCoveringsandPossibleLinkstoMultipleChemical
Sensitivity
Examinedmaterialsafetydatasheets,depositiontranscriptsandthescientificliteraturetodeterminethe
whetheramanufacturedfloorcoveringcouldaccountforeffectsinhumans.Testimonyexpectedinearly2017.
2016
ExpertConsultationontheEffectsofPrescribedAnti-Depressants,OpiatesandEpilepsyMedicationsduringPregnancy
Wroteanopinionabouttheeffectsofthesevariousdrugsduringpregnancy,includingpossibleeffectontheinfantafteritsbirth.
2016
ExpertConsultationonEffectsofAnti-DepressantandOpiateDrugsinHumans
Providedawrittenopinionregardingthecombinedeffectsofaselectiveserotoninreuptakeinhibitor,a
benzodiazepineandanopiateonanindividual’smentalstate.Exposuretothesedrugslikelyoccurredfromapoisoningattempt.
2016
OpinionontheInterpretationofPositiveUrineTestsforMarijuanafollowingWeightLoss
WroteanopinionregardingtheincreasesobservedinthelevelsofTHC-COOH(metaboliteofTHCfrom
marijuana)inurinethatareduetoreleaseofTHCfromfat.TheTHCwaslikelyusedseveralweeksormonthspriortotesting.
2016
ConsultationabouttheAssociationofDisinfectionByproductsinDrinkingWaterwithVariousHealthEffects
Conductedaninvestigatedofthescientificliteratureregardingaclaimthatchlorineandtrihalomethaneswereassociatedwitharangeofdiseases,includingkidneydiseaseandcancer.
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2015-16 ExpertReportontheToxicityofDioxin-likeChemicals
Providedareportanddepositionondifferencesintoxicityofthevariousdioxin-likechemicals.2015
ConsultationwithaWaterUtilityregardingtheHealthEffectsofRadiuminDrinkingWater
Workedwithahealthphysicisttodevelopajointopinionaboutthehealtheffectsofradiumand
potentialtreatmenttechnologiestoenabletheutilityinanacquisition.2015
DepositiontoStateandFederalEnvironmentalRegulatorsandPrivateSectorAttorneysaboutthe
EffectsofSeleniumonHumanHealth
ProvideddepositionregardingthetoxicityofseleniumdischargedintostreamsnearAppalachiancoal
mines.2015
ExpertReportontheLikelihoodofFungalEyeInfectionafterContactwithFertilizer
Investigatedexposureofplaintifftoairbornefertilizerparticlesduringspreadingoperations.Thefertilizer
particlesenteredtheeyeandfungalinfectionofthecorneaensued.Wroteareportthatresultedinimmediatesettlementinfavoroftheplaintiff.
2015
ExpertOpinionontheToxicityandHealthEffectsofSyntheticCannabinoidsInJanuary,providedamemorandumtotheFairfaxCounty,VAPoliceDepartmentdetailingthehealtheffectsofsyntheticcannabinoidsusedintheillegaldrugsknownas“spice”or“K-2.”
2014-15DevelopmentofStatisticalBackgroundScreeningMethodsforUseataPotentialSuperfundSiteInDecember,providedacomparisontobackgroundforconcentrationsofarsenicandpolycyclicaromatichydrocarbonsatasitecurrentlygoingthroughtheHazardRankingSystem.
2008-14ExpertConsultationandDepositiononRegulatoryDecisionsataSuperfundSiteProvidedanexpertreporttoattorneysabouthowthepresenceofdioxin-likechemicalsandPCBsaffectedtheregulatoryactivities/decisionsataSuperfundsiteinNewEngland.In2014,providedadepositioninWash.,DC.
2014
ReportonTSCAComplianceStatusofRecentDataandPublicationsontheHealthEffectsofChromiumPreparedareportonthedeterminationsofwhetherthesedataandpublicationscouldbeconsidered“new”information.Thepurposewastoprovideattorneyswithriskinformationasindicatedinthe1978TSCASection8(e)PolicyStatementonSubstantialRiskNotificationstoEPA.
2010 RebuttalReportonHexavalentChromium
Preparedareportrebuttingareportsubmittedbytheexpertworkingforopposingcounselregardingthe
healthandenvironmentaleffectsofhexavalentchromium.2008-10ExpertTestimonyregardingtheEffectsofInorganicMercury
Providedanexpertreporttoattorneysinachildcustodymatterregardingthelongtermneurologicalandpsychologicaleffectsofinorganicmercury.ProvidedexperttestimonyonthismatterinfamilycourtinFultonCounty,GAregardingthetoxicityofinorganicmercury.
2009
ConsultationandStatisticalModelingregardingtheDose-ResponseofPerfluoroctanoicAcid(PFOA)inHumans
PFOAisusedintheproductionofTeflon.Providedconsultationaboutdose-responsemodelingasasub-contractortoaconsultingfirminTallahassee,FLtobeusedinlitigationsupport.
2009
ExpertConsultationregardingUSEPA'snewArsenicToxicityCriterionProvidedamemorandumtoattorneysandpersonnelfromelectriccompaniesontheramificationsofEPA'sproposedchangeintheoralcancerslopefactorforArsenic.
2008
RiskCommunicationandExpertConsultationregardingAerosolEmissionsRetainedasanexpertintoxicologybyattorneysforGeorgiaPowertoprovidescientificconsultationandriskcommunicationregardingemissionsofseveralinorganicchemicalsfrompowerplants.
2007
ProBonoEvaluationofExposuretopara-dichlorobenzene(PDB)ProvidedanexpertreportonexposureandpotentialliverdamageinanindividualworkinginabotanylaboratoryinwhichPDBwasusedasaninsectfumigantforplantspecimens.
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2006
AssessmentofPossibleDrug/AlcoholImpairmentinforWorkman’sCompensationExaminedquickurinedrugscreenresultsshowingalcoholandmarijuanauseanddevelopedanassessmentofpossibleimpairment.
2006
ExpertConsultationontheRecentHistoryofArsenicRegulationbyEPAProvidedamemorandumdetailingthehistoryofarsenicregulationasasoilcontaminantbyEPAheadquartersandbyRegion4EPA(Southeast)since1988tosupporttheeffortsofattorneysregardingaSuperfundsite.
2006
ConsultingExpertregardingIndoorDampnessandMoldServedasaconsultingexpertregardingadverseeffectsofexposuretoindoordampness,associatedmoldandbacteriaandthedisinfectantchemicalsusedinthecleanup.
2003-4
ModelofChemicalReleasefromaRailroadTankCarDevelopedamathematicalmodelforthereleaseanddispersionofadensegas,ethylacrylate,fromarailroadtankcar.Thegasproducedorganolepticeffects,andathigherexposure,toxiceffects.Sourcecharacteristicswereobtainedusingbasicphysicalchemicalprinciples.Dispersionmodelingwasperformedfordensegasdispersionincomplexterrain.
2003
ExpertTestimonyinEPAvs.NormanC.MayesAsanEPAtoxicologist,providedtestimonytoAdministrativeLawJudgeBarbaraGunningregardingthehealtheffectsofbenzeneandotherfuelcomponentsandenvironmentalsamplingaroundundergroundstoragetanks.
2002-4
AirandExposureModelingandPBPKModelDevelopmentofCreosoteExposureataWoodTreatmentFacilityDevelopedacomprehensivedatabaseofchemicalsinwoodpreservativemadewithcoaltarcreosote,amathematicalmodeloftheairconcentrationsofthesechemicalsatawoodtreatmentfacility,andasecondmodelforhumaninternalexposuretothesechemicalsthatincludedingestion,inhalationanddermalroutes.
2001-2
ExpertTestimonyregardingCalibrationoftheIntoxilyzer5000DevelopedtestimonyregardingthecalibrationproceduresoftheIntoxilyzer5000,the"breathalyzer"usedinGeorgiaforDUItesting.ChargesinDUIcasesweredroppedpriortohistestimonyinthethreecasesinwhichDr.Simonwasinvolved.
2000
ChemicalReleasefromaRailroadTankCarDevelopedamodelofreleaseandtransportofacrylamidefromarailroadtankcarforuseinlitigation.
TEACHING 2014
Instructor,EnvironmentalRiskAssessmentandCommunication,EHSC8110,UniversityofGeorgia
TaughtagraduatelevelcourseIntheSchoolofPublicHealthusinghistextbook,“EnvironmentalRiskAssessment:AToxicologicalApproach.”
2008
LectureontheToxicologyofPCBsDevelopedandpresentedatrainingsegmentaspartoftheToxicSubstanceControlAct(TSCA)trainingforelectricpowercompanypersonnelattheGeorgiaPowerCompany.
2008
IntroductiontoRiskAssessment,atwo-dayclassfortheOntarioMinistryofEnvironmentWithanotherscientist,developedandtaughtaclassonriskassessmentfornewlyhiredMinistrypersonnel.
2005
ProbabilisticRiskAssessmentandStatistics,ashortcoursetoMichiganDepartmentofEnvironmentalQualityWithanotherscientist,presenteda1½dayclassonprobabilisticriskassessmentandstatisticsaspartofaworkshopsponsoredbytheSocietyforRiskAnalysisandInterstateTechnologyRegulatoryCouncil.
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2003
GraduateCourseinSimulationModeling,GeorgiaStateUniversityTaughtagraduatelevelcourseinSimulationModelingincludingstatistics,probabilisticmethodsandtime-dynamicdifferentialequationmodels.
2003
ShortCoursetoOntarioMinistryofEnvironmentonProbabilisticRiskAssessmentWithanotherscientist,developedandtaughtaclassonprobabilisticriskassessment,includingprobabilisticapproachestodose-responsetopersonnelattheOntarioMinistryofEnvironmentinToronto,Canada
2001-06UniversityofGeorgiaGraduateCourseinEnvironmentalRiskAssessmentOnthreeseparateoccasions,taughtagraduate-levelclassonEnvironmentalRiskAssessmentlasting15weeks,3hoursperweek.
2001
ShortCoursetoTexasNaturalResourcesConservationCommissiononProbabilityDistributionsWithanotherscientist,developedandtaughtaclassonstatisticsandprobabilitydistributionstodatatoTNRCCpersonnel.
2000
WorkshopsonProbabilisticRiskAssessmentPerformedasanEPAtoxicologist.In1999and2000,workedwithDr.SteveRobertsoftheUniversityofFloridatoorganizetwoworkshopsonPRAsponsoredbyEPA,NIEHSandtheUniversityofFlorida.
1999
ShortCoursetoTexasNaturalResourcesConservationCommissiononProbabilisticRiskAssessment
Withanotherscientist,developedandtaughtaclassonprobabilisticriskassessmenttoTNRCCpersonnel.1997
ShortCoursetoNavyEnvironmentalHealthCenterpersonnelonProbabilisticRiskAssessment
Withanotherscientist,developedandtaughtaclassinprobabilisticriskassessmentNavypersonnelinNorfolk,VA.
PRODUCT LIABILITY AND SAFETY EVALUATIONS 2013
PresentationtoaFrenchGovernmentAgencyonProductSafety
ProvidedareportwithestimatesofbothtoxicityandexposuretorailworkersontheuseofasyntheticdielectriccompoundmanufacturedbyacompanyintheUK.MetwithFrenchgovernmentpersonneltodiscussthereport.
2012
AssessmentofRiskfromMetalPlatingFlakingfromanAuxiliaryFaucetusedwithaWaterFilter
Developedriskestimatesforwaterconsumersfromdissolvedmetalsandmetalflakesfromthefaucet.This
assessmentwasusedinternationallyandthereforeincorporatedWorldHealthOrganizationmethodology.
REGULATORY TOXICOLOGY 2018
LeadAuthorofaDocumentDevelopingToxicityReferenceValuesforInorganicArsenic
ThereportwasdevelopedforHealthCanada,theCanadianequivalentoftheUSEPA.Datafrommany
largeepidemiologicstudieswereusedforexposure-responsemodelinganddevelopmentofTRVssuchasreferencedosesandcancerslopefactor.CustomsoftwaretoperformthemodelingwasdevelopedintheRsoftwarelanguage.
2017 ReporttoChemicalIndustryTradeGrouponPerfluorinatedCompounds
Thesecompoundshavebeenusedforstainresistanceandwaterproofingformanyyears.Theyare
ubiquitousintheenvironmentandhumanbodyburden.Thereportprovidesadviceaboutwhichcompoundsbeartheleastrisktohumanhealth.
2016-17LeadAuthorofaToxicologicalReviewofInorganicArsenicandOrganicArsenicals
ThereviewwasdevelopedforHealthCanada,theCanadianequivalentoftheUSEPAandthepurposewas
toexaminethefeasibiityoftheintegratinghuman,animalandinvitrolaboratorydatatoprovideanupdatedtoxicityevaluationofarsenic.
2016
Publicationtitled“HowWellDoHTSCarcinogenCharacteristicsPredictCarcinogenicity?”
Providedstatisticalanalysis,graphicsandnarrativedevelopmentforthispaperincollaborationwith
scientistsfromuniversitiesandindustrytradegroups.
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2016
AnalysisofChemicalSimilarityforAbuseLiabilityofCandidateDrugMolecules
Conductedastatisticalanalysisofchemicalsimilaritybetweentwocandidatedrugsandsubstancesonthe
DEAControlledSubstanceListtoaddresstheissueofpotentialabuseliability.2015-16WhitepaperonCausalAssociationsbetweenFlameRetardantExposureandFirefighters’Diseases
DevelopedfortheFlameRetardantsAlliance.2015
AdverseOutcomeSummaryPathwaysforChemicalswithUncertaintyabouttheModeofAction
Adverseoutcomepathways(AOPs)arebeingusedbyEPAandOECDtoformadatawikiforeventual
interpretationofhigh-throughputinvitrodata.DevelopedseparatesummariesofAOPsforfourchemicalscarcinogenicinanimalsusingtheassumptionofmutagenicityasmodeofactionandhyperplasia/cellproliferationasthemodeofaction.
2015
RevisionoftheToxicityFactorforthePesticideToxapheneforuseattheHerculessiteinBrunswick,GA
Developedarevisedestimateofthetoxicitycriterion(ReferenceDose)forthepesticidetoxapheneforuse
inanewriskassessmentfortheHerculessiteinBrunswick,Georgia.2014-15ReportonBayesianStatisticalMethodsusedintheNRC(2014)ReviewofIRIS
Developedareportexamining24toxicityfactorsfromEPA’sIntegratedRiskInformationSystemdatabase,
thesubjectofarecentreviewbytheNationalResearchCouncil.ThereportcomparedEPA’smethodswiththoserecommendedintheNRCreport.
2014
PresentationonarsenicandchromiumatEPA’sIntegratedRiskInformationSystem(IRIS)BimonthlyMeeting
InJune,presentedmodeofactioninformationforarsenicandhexavalentchromiumatEPA’sIRISmeeting.ThepurposeofthesemeetingsistoseekinputfromstakeholdersfordevelopmentofIRISriskassessments.
2013
PresentationonQuantitativeMethodsforModeofActionAnalysistoEPA’sBimonthlyIRISMeeting
InDecember,presentedslidesanddiscussiontoEPAandotherstakeholdersbasedonthepaperwritten
withILSI/HESItitled“TheUseofModeofActionInformationinRiskAssessment:QuantitativeKeyEvents/Dose-ResponseFramework(Q-KEDRF)forModelingtheDose-ResponseforKeyEvents.”
2013-16DevelopmentofWikifilesontheAdverseOutcomePathwayfortheOrganisationforEconomicCooperationandDevelopment(OECD)
WroteandeditedwebpagesforuseinthenewAOPWikisponsoredbyOECD,EPAandothers.ThepurposeofthecollectionofAOPsandtheWikiistocontextualizeinvitrodataforuseinriskassessment.
2013
PreparationofaReportProvidingDerivedLD50ValuesforMetalsinFlyAsh
DosesofflyashrepresentingtheLD50formetalsweredevelopedforflyashproducedbyanincinerator
operatedbyalargecountygovernmentinsouthernCalifornia.2013
DevelopmentofEvidenceTablesforEPA’sIntegratedRiskInformationSystem(IRIS)Assessments
Developedtabularformatforpresentingmodeofactionandtoxicityinformationconsistentwiththe
NationalAcademyofSciences’ReviewoftheEnvironmentalProtectionAgency'sDraftIRISAssessmentofFormaldehyde.PresentedthetablesandaccompanyingrationaletoEPAIRISstaffusinghexavalentchromiumasanexample.
2013
DevelopmentandPresentationofResponsestoChargeQuestionsforEPA’sFederalInsecticide,Fungicide,andRodenticideAct(FIFRA)ScientificAdvisoryPanel
Wroteresponsesonphysico-chemicalscreeningandtherainbowtroutExpertSystemforestrogeniceffects;presentedtheresponsesattheFIFRA/SAPmeetingatEPAHeadquarters.
2012 ReviewofEPA’sToxicologicalReviewofAmmonia
ReviewedtheEPAdraftdocumentforammoniatodetermineconsistencywithrecommendationsfrom
theNationalAcademyofSciences.PresentedresultsatEPA’sIRISlisteningsessiononAmmonia.
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2012
Reviewof2012TexasCommissiononEnvironmentalQuality(TCEQ)“GuidelinestoDevelopToxicityFactors”
TCEQdevelopsitsowntoxicitycriteriaanddoesnotdependonEPA’sIRISdatabase.PreparedcommentsontheguidanceforsubmissiontoTCEQ.
2012
PreparationofaWhitePaperandmanuscriptforpublicationonValidationofEPA’sToxCast™SuiteofHighThroughputInVitroAssays
Wrotenarrativepaperandmanuscriptforachemicalindustrytradegrouponissueswithvalidationoftheseassaysforchemicalscreeningandprioritization.
2011
DevelopmentofPhysiologically-basedPharmacokineticModelsforDioxin,PCBs,DDT,HexachlorobenzeneandOrganophosphatePesticidesforuseasteachingtoolsattheAgencyforToxicSubstancesandDiseaseRegistry(ATSDR)
DevelopedPBPKmodelsinBerkeleyMadonnasoftwareforuseasteachingaidsforpersonnelatATSDR.2011
ReviewofEPA’sPhysiologicallyBasedPharmacokineticModelforAcrylonitrileUsedintheIRISRisk
Assessment
ReviewedtheMATLABcomputercodeandoutputforoptimizationofparametersusedinthismodel.
TOXICOLOGYANDREGULATORYANALYSISOFDIOXIN-LIKECHEMICALSINCLUDINGPOLYCHLORINATEDBIPHENYLS2012-15ModelingofDioxin-inducedGeneExpressioninBreastCancerCells
Developedamodelofgeneexpressionusingstochasticsimulationmethodsthatreproducedseveralphenomenasuchasnon-monotonicdoseresponsecurves.
2012
DevelopmentofaMarginofExposureforEnzymeInductionfromDioxinExposureforComparisonwithRecentEPAToxicityFactorsforaWeight-of-Analysis
Usingdatafrombothhumansandlaboratorytestspecies,determinedthedoseatwhichanincreaseinthyroidhormonemetabolismcouldbeexpectedandcomparedthisdosewiththecurrentEPAreferencedosebasedonthyroideffectsinnewborns.
2011
Inclusionof2009ReferenceDosefor2,3,7,8-Tetrachlorodibenzodioxin(TCDD)intheITERandTOXNETdatabases
Presentedconclusionsfroma2009publicationtoapeerreviewpanelconvenedbyToxicologyExcellenceinRiskAssessment(TERA)forplacementintheInternationalToxicityEstimatesforRiskAssessment(ITER)databaseandlinkedtotheTOXNETdatabaseattheNationalLibraryofMedicine.
2011
DevelopedaRevisedToxicEquivalenceFactor(TEF)for2,3,7,8-Tetrachlorodibenzofuran(TCDF)
TCDFisadioxin-likechemicalthatismetabolizedandeliminatedwithinhoursincontrasttootherdioxin-
likechemicalsthatpersistinthebodyformanyyears;developedanestimateoftheTCDFTEFthatincorporatesthisrapidmetabolismforpresentationataninternationalconferenceinBrussels,Belgium.
2011
AllianceforRiskAssessmentPresentationonDioxinusingScienceandDecisionsConceptualModels
PresentedresultsfromtheapplicationofdoseresponsemethodsdescribedNationalResearchCouncil's2009
Report"ScienceandDecisions:AdvancingRiskAssessment"todioxin.TheaudiencewasanexpertpanelthatincludedseveraloftheauthorsoftheNRCreport.
2010
ReportonBiota-SedimentAccumulationFactor(BSAF)forAroclor1260,aCommercialPCBMixture
ProvidedareviewandcommentaryonthedevelopmentofaBSAFforAroclor1260(PCBmixture)andits
generalapplicabilitytoPCBcontaminatedsites.2010
RapporteurataWorkshoponDose-ResponseApproachesforNuclearReceptor-MediatedModesof
Action
Ledpaneldiscussionandprovidedthepresentationofthereportforthepanelexaminingthemodeof
actionofthearylhydrocarbonreceptorthatmediatesgeneexpressionfromdioxin-likechemicals.2010
RiskAssessmentforDioxinbasedontheOccurrenceofChloracneinHumans
Developedariskassessmentfor2,3,7,8-tetrachlorodibenzo-p-dioxinbasedsolelyondatafromhumans
andpresentedtheworkattheDioxin2010meetinginSanAntonio,TX.
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2010
AnalysisofResponsesofHumanandRodentLiverCellstoDioxin-LikeChemicals
Conductedstatisticalanalysisofgenomicandproteomicdatainresponsetothreedioxin-likechemicals
fromhumanandrodenttissuesinvitro.2010
CancerSlopeFactorsandToxicityEquivalenceFactorsforDioxin-LikeChemicalsbasedonInternalDoses
Developedacomparisonofthetoxicityoffourdioxin-likechemicalsbasedontissueconcentrationsfrom
NationalToxicologyProgrambioassaysusingphysiologically-basedpharmacokineticmodelinganddoseresponsemodels.
2009
EvaluationofToxicityEquivalenceFactorsforDioxin-likeChemicalsbasedonexternaldoses
DevelopedacomparisonofmethodsusedtodevelopvaluesforTEFsusedinriskassessmentsofdioxin-
likechemicals.2009
EPAFederalAdvisoryCommitteeAct(FACA)WorkshoponDIoxin
Attendedworkshopontheriskassessmentof2,3,7,8-tetrachlorodibenzodioxin(TCDD);providedpublic
commentaryonEPA'sproposedmethodsforrevisingthe2003dioxinreassessment.2008
ReviewofPCBEcotoxicologyInformationintheBaselineEcologicalRiskAssessmentfortheLCP
ChemicalSuperfundSite,Brunswick,GA
ReviewedthetoxicityassessmentforPCBsfortheecologicalriskassessmentforthissitetoensure
consistencywiththevaluesandapproachusedinthehumanhealthriskassessment.2007
ComparisonbetweenBloodLevelsofDioxininresidentsofMidland,MIandthoseinratsassociated
withAdverseEffects
Conductedacomparisonbetweenhumanbloodlevelsof2,3,7,8-TCDDand2,3,4,7,8-PeCDFmeasuredin
humansintheUniversityofMichiganDioxinExposureStudyandestimatedbloodlevelsinratsfrombioassayspublishedbytheNationalToxicologyProgramin2006.
2007
DevelopmentofaRiskAssessmentMethodologyBasedonChangesinGeneExpression
Withveryrecentinformationondioxin-relatedgeneexpressionchangesintheliver,developedamethod
forusingthesechangesasabiomarkerfortheprogressiontotype2diabetes.2007
WhitepaperontheNon-cancereffectsonhumansofDioxin-likeChemicals
Collectedscientificinformationrelatedtopotentialandactualhumanhealtheffectsfrompublished
studiesoftheYu-Cheng/Yushopoisoning,theSevesoexposure,theBASFplantexposureandtheVietNamRanchhands(AgentOrangehandlers)andotherstoassessthelikelihoodofvarioushealthoutcomesfromdioxinexposure.
2007
SoilCleanupStandardsforDioxinrelatedtotheGeorgiaHazardousSubstancesResponseActforasecondarycoppersmelter
DevelopadioxincleanuplevelinsoilforconsiderationbytheGeorgiaEPDthatincludedanepidemiologicalstudyofdioxininthebloodofworkersatthesmelter.
2005
DevelopmentofSurrogateValuesforReportedDioxinConcentrationsBelowtheAnalyticalDetectionLimit
PerformedasanEPAtoxicologist;theuseofcontract-specifiedreportinglimitsasnondetectsurrogatesfordioxinanalysisleadstolargeoverestimatesofsoilconcentrations;identifiedamoreaccuratenondetectsurrogatevaluebasedontheactualchemicalanalysis.
2005
ReassessmentfortheNeedforPCBCongenerAnalysisattheAnniston/SolutiaPCBSite
PerformedasanEPAtoxicologist;comparedresultsfromPCBcancerbioassaysofthecancerpotencyof
dioxin-likePCBs.2004-5
GeostatisticalmodelingofdioxinconcentrationsinsoilatSuperfundSitesinFlorida
PerformedasanEPAtoxicologist;theseanalysesdemonstratedthatcleanupatthesesiteshadbeen
successfulandappropriateforthepredictedlanduse;theanalysesalsoshowedthatdioxinoccurringoff-sitewasunrelatedtoon-sitecontamination.
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HUMAN HEALTH AND ECOLOGICAL RISK ASSESSMENT AND RISK
COMMUNICATION 2014
DevelopmentofaProbabilisticRiskAssessmentforNellisDunesRecreationArea,Nevada
WorkedinconjunctionwithacademicscientistsattheUniversityofNevada,MontanaStateUniversityand
theUniversityofSouthCarolinatousenewlydevelopedinformationofthegeologyofNellisDunesandsite-specifictoxicitybioassaysofdusttocompleteariskassessmentforexposuretodustatthisrecreationarea.
2012
ParticipationonaRiskAssessmentTeamdevelopingmethodologytoassessaSuperfundsiteconsistingofalargeareafloodplain
Evaluatedriskassessmentoptionsandlandusetosupportcleanupdecisionsatanimpactedareacomprisingseveralsquaremilesandmanyrivermiles.
2010
ScreeningLevelEcologicalRiskAssessment(SLERA)forasiteinFloweryBranchinHallCounty,Georgia
Atanindustrialparknearaninterstatehighway,theareaofpotentialecologicalconcernconsistedofa
storm-waterretentionpondandastream.InvestigatedthesiteanddevelopedtheSLERAdocumentforsubmissiontotheGeorgiaEnvironmentalProtectionDivision.
2009
StreamlinedHumanHealthandEcologicalRiskAssessmentstosupportRemovalActionattheNabesnaMineSiteinNabesna,Alaska
ThissiteislocatedintheWrangell-St.EliasNationalParkandwasafunctioninggoldmineintheearly20thcenturywithhighconcentrationsofmetalsassociatedwithminetailingsandacidminedrainage;developedbothriskassessmentstosupportanon-time-criticalactionatthesite.
2009
DevelopmentofGeorgiaRiskReductionStandards(RRS)forDrexelChemicalCompanyinCordele,GAandanothersiteinNorthGeorgia
CalculatedGeorgiaRRSvaluesforthissite;negotiatedinpersonandbyteleconferencewithGeorgiaEnvironmentalProtectionDivisionpersonnelregardingtheappropriateuseoftoxicitycriteria.
2009
RiskCommunicationandRegulatoryReviewrelatedtotheTVACoalAshSpillinKingston,TN
ProvidedriskcommunicationatpublicavailabilitysessionforboththeAmericanCoalAshAssociationand
TVA;reviewedsubmissionstoEPAdevelopedbyTVA.2008
QualityAssuranceforFishConsumptionRiskAssessmentonthePassaicRiver
Reviewedandprovidedcommentsonboththeaccuracyandconceptualizationoftheriskassessment.2008
DevelopmentofGeorgiaRiskReductionStandardsforTrivalentandHexavalentChromiumandseveral
VolatileOrganicChemicals
CalculatednumericalstandardsunderGeorgia'sHazardousSiteResponseRule391-3-19asa
subcontractorinsupportofapropertysaleandtransfer2008
EvaluationofSoilConcentrationsofArsenicwithanEmphasisonLocalBackgroundataPowerPlant
DevelopedareportforsubmissiontotheGeorgiaEnvironmentalProtectionDivisionregardingareleaseof
wastematerialcontainingarsenicthatoccurredbystormwaterrunoff;thereportconsideredthegeologyandlocalbackgroundconcentrationandincludedastatisticalanalysis.
2008
StatisticalEvaluationofSolventDatainGroundwaterandCritiqueofATSDRHealthAssessmentofaSuperfundSite
ProvidedareportthatincludedsuggestionsandcommentsontheATSDRReport.PerformedastatisticalanalysistorefinetheconclusionsreachedandcritiquedthemethodologyfortheHealthAssessment.
2008
InvestigationintotheScientificBasisofLandDisposalLimitof50partspermillionforPCBs
Underthe1979ToxicSubstancesandControlAct(TSCA),EPAhasplacedanupperlimitof50ppmforland
disposalofPCBs.Investigatedthescientificbasisofthisvalueforapplicationataformerchlor-alkaliplantsiteinNorthCarolina.
2008
ReviewofCleanupTargetLevelsofFloridaDepartmentofEnvironmentalProtection
ProvidedareviewoftheCleanupTargetLevelsusedforregulationbyFloridaDepartmentof
EnvironmentalProtection.
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2007
EvaluationofCalculationMethodsfortheGeorgiaRiskReductionStandardsoftheGeorgiaHSRAProgram
ExaminedRRSvaluesforsoilandgroundwaterdevelopedforasiteinnorthGeorgiaandprovidedanexplanationoftherationaleunderlyingdiscrepanciesinthecalculatedvalues.
2007-9
RiskAssessmentfortheExposuretoMercuryandPCBsfromcontactwithMarshSedimentandConsumptionofFishandGameBirdsattheLCPChemicalSuperfundSite,Brunswick,GA.
Conductedariskevaluationforsedimentexposureand,fishconsumptionwithdevelopmentofsite-specificfishconsumptionestimatesandasite-specificsedimentexposureestimateforanupdatedRemedialInvestigationReportforsubmissiontotheUSEnvironmentalProtectionAgency.
2007
ProBonoEvaluationofGeorgiaDNRFishAdvisoriesforPCBsandMercury
EvaluatedcurrentfishadvisoriesnearBrunswick,GAforDr.RandyManning,theGeorgiastate
toxicologist.2007
GeorgiaRiskReductionStandardsforPCBs,mercuryandotherchemicalsinSoilandGroundwateratthe
LCPChemicalSuperfundSite
Prepareddetailedcalculationsofsoilandgroundwaterscreeningvaluesbasedbothondirectexposure
andtransferofchemicalsfromsoiltogroundwater.2006-10RiskAssessmentfortheResidentialExposureScenarioforPCBsandmercuryinUplandSoilsattheLCP
ChemicalSuperfundSite,Brunswick,GA.
Conductedariskevaluationforresidentialexposure.TheoriginalriskassessmentfortheLCPsitedidnot
includeanestimateofrisktoon-siteresidentsorotherhumanreceptorswithasmallexposureunit(ca.0.5acres).ThisriskevaluationwillbepartofanupdatedremedialinvestigationtosubmittoUSEPA.
2006-7
RiskAssessmentforConsumptionofEstuarineFishcontainingToxapheneResiduesbyCoastalGeorgiaResidentsrelatedtheHerculesChemicalSuperfundSiteinBrunswick,GA
DevelopedfishconsumptionestimatesforcoastalGeorgiaresidentsbasedontheprevioussurveysintheBrunswickareausedalongwithpublishedworkonthetoxicityoftoxaphenetosupportaprobabilisticriskassessmentforfishconsumptionpreparedforUSEPA.
2006
DevelopmentofaPhysiologically-basedPharmacokineticModelforCopperinMigratoryBirdsforEcologicalRiskAssessmentofMine-AssociatedTailingsPonds
Highcopperconcentrationsinwaterassociatedwithacidminedrainagemaybetoxictobirds;developedofaPBPKmodelofcopperabsorption,distribution,metabolismandexcretion(ADME)injuvenileducksandadultgeese;conductedafeasibilitystudyofincorporatingthephysiologicalchangesassociatedwithmigrationintothemodel.
2006
DevelopmentofaPreliminaryRiskAssessmentforSeleniumaspartofaProposaltoAddressOverallEffectsofSeleniuminaRiverSystem
Developedhumanhealthandecologicalriskestimatesforseleniummigratingfromcoalpilesintoariver.Theseestimatesincludedconsumptionoffishandwaterbyhumans.
2006 EvaluationofGeorgiaDNRFishAdvisoriesnearBrunswick,GA
ConductedanevaluationoffishadvisoriesforToxapheneandPCBspublishedbytheGeorgiaDepartment
ofNaturalResources.2006
DevelopmentofawhitepaperpresentingthehistoryofProbabilisticRiskAssessment(PRA)atEPA
ReviewedEPAguidancedocumentsandscientificliteratureandproducedadocumentthatdetailedthis
completehistoryofPRAatEPAandsuggestedlikelyusesofPRAinthefuture.2005
RiskCommunicationregardingsolventsingroundwateratAugusta,Georgia
AsanEPAtoxicologist,providedinformationtocitizensatapublicmeetingregardingthepossiblehealth
effectsoftetrachloroethyleneandtrichloroethyleneingroundwaterrelatingtoaRCRAsite.2005
ReviewofProposedArsenicToxicityAssessmenttobeplacedonEPA’sIRISDatabase
AsanEPAtoxicologistandconsensusreviewerforEPA’sIRISdatabase,reviewedandprovidedcomment
onproposedchangestothearsenictoxicityassessment.
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2004-5
RiskCommunicationtoCommunityAgainstPollution(CAP),acitizensgroupinAnniston,AL
AsanEPAtoxicologist,developedarelationshipwithCAPandpresentedinformationonthehealtheffects
ofPCBsatseveralpublicandcommunitymeetings.2004
ProvidenceParkEcologicalRiskAssessment
Conductedascreeningecologicalriskassessment(SLERA)forasiteinFultonCounty,GA2004
RiskCommunicationregardingTrichloroethylene
AsanEPAtoxicologist,providedinformationtotheCitizen'sAdvisoryGroup(CAG)atAnnistonArmy
Depotandagroupofconcernedcitizensaboutthehealtheffectsoftrichloroethylene.2003-5
DevelopmentofEPA'sGuidanceonSurfaceSoilCleanupatHazardousWasteSites:Implementing
CleanupLevels
AsanEPAtoxicologist,developedaguidancedocumentthatpresentedmethodsforapplyingrisk-based
cleanuplevelsasareaaveragesratherthannot-to-exceedlevels.2003
SoilCleanupStrategyforaSkeetRangeatNavalAirStationCecilFieldinJacksonville,FL.
AsanEPAtoxicologist,usedbothgeostatisticsandexposureassessmenttorefinethesizeofthearea
needingremediation.2000
DiscussionofFlorida’sSecondaryDrinkingWaterStandardsbasedonOrganolepticEffects
AsanEPAtoxicologist,investigatedthebiologicalbasisofFlorida’ssecondarydrinkingwatercriteriafor
aluminum,iron,manganeseandsilverforwhichsecondarystandardsbasedonesthetics(smellandtaste)werebelowhealth-basedcriteria.
2000
MemorandumpresentingAmendedGuidanceonEcologicalRiskAssessmentatMilitaryBases:ProcessConsiderations,TimingofActivities,andInclusionofStakeholders
AsanEPAtoxicologist,authoredamemothatenabledecologicalriskassessmentsatDODfacilitiestobecompletedinatimelymannerandensuresthatriskassessmentactivitiesoccurattimesconsistentwithDODfundingschedules.
1996-9
DevelopmentofRiskAssessmentGuidanceforSuperfund,Part3.ProcessforConductingProbabilisticRiskAssessment
AsanEPAtoxicologist,madesignificantcontributionstothisguidance,whichreceivedEPA'sScienceAchievementAwardin2001.
1995 Region4Bulletins:RegionalRiskAssessmentGuidance
AsanEPAtoxicologist,authoredRegion4riskbulletinsonToxicityAssessmentandonDevelopmentof
RemedialGoalOptions.
ADDITIONAL WORK IN TOXICOLOGY
2014-16DevelopmentofanAdverseOutcomePathwayDocumentforaMutagenicModeofActionforCancer
Workedwithindividualsfrombothgovernmentandtheprivatesector,collaboratedonamanuscript
detailingthemodeofaction/adverseoutcomepathwayforlivertumorigenesisinanimalsandhumansbyaflatoxinB1,atoxinproducedbyfungiandubiquitousingrainsandgroundnuts.
2009-16OngoingScientificConsultationontheHealthEffectsofHexavalentChromium
Providesongoingsupportfortoxicologicalandriskassessmentinformationfortoxicologicalissuesrelated
tohexavalentchromiumforaFortune100company.2010
StatisticalAnalysisofReproductiveEndpointsinRatsExposedtoFlameRetardantChemical
PerformedstatisticalanalysisofdichotomousdataforreproductiveendpointstoinformaEuropean
consortiumaboutthemostappropriatemethodsfordataanalysis.2009
ResponsestoEPAChargeQuestionsforReviewofthe2009ToxicologicalReviewof1,4-Dioxane
WroteresponsestoEPA's"ChargetoExternalReviewersfortheToxicologicalReviewof1,4-Dioxane”
relatedtouncertaintyanalysis,physiologically-basedpharmacokinetic(PBPK)modelingandBenchmarkDosemodeling.
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2009
Physiologically-basedPharmacokineticModelsforMethylmercury,Arsenic,CadmiumandBisphenol-Aforuseasteachingtools
TranslatedexistingmodelsintotheBerkeleyMadonnacomputersoftwareforuseasteachingaidsforpersonnelattheAgencyforToxicSubstancesandDiseaseRegistry.
2008
WhitepaperontheEthicsofEnvironmentalRegulationandCompoundingConservatisminRiskAssessmentfortheOntarioMinistryoftheEnvironment
Usedhistoricalsources,philosophicalliteratureandmodernscientificpublicationstoprovideanunderstandingoftheextenttowhichenvironmentalregulationsandstandardsarebasedontheprecautionaryprinciple.
2008
AssessmentofConservatismofSoilandGroundwaterStandardsfortheOntarioMinistryoftheEnvironment
Assessedthelevelofconservatismofproposedenvironmentalmediastandardsusingstatisticalmethods.2007
ExpertPanelDevelopingaProtocolforToxicityTestingofaLegacyPesticideMIxture
Servedonapaneltorefineaprotocolfortoxicitytestingofsoilconsideringbothindividualpesticide
isomersandmixtures.2004
ConsultationwithEPARegion4MercuryStudyGroup
AsanEPAtoxicologist,providedinformationtoagroupofRegion4personneltoaddressanewspaper
editorialregardinghumanhealthandmercury.
PeerReviewsandPeerConsultations2018
RegulatoryToxicologyandPharmacology,GioB.Gori,Editor,“BiomonitoringEquivalentsforCyanide”2017
EnvironmentInternational,LesaAylward,Editor,“Ananalysisofcumulativerisksbasedonbiomonitoring
dataforsixphthalatesusingtheMaximumCumulativeRatio”2017
ToxicologicalSciences,WilliamH.Farland,Assoc.Editor,“Identificationofnoveluncertaintyfactorsforhealth
hazardandriskassessment:Applicationtocleaningproductingredients”2097
EnvironmentInternational,LesaAylward,Editor,“ExcretionofDi-2-ethylhexylPhthalate(DEHP)Metabolites
inUrineisRelatedtoBodyMassIndexBecauseofReverseCausality”2017
RiskAnalysis,L.AnthonyCox,Editor,“CumulativeLow-DoseResponseAssessment:AnEmergentModelFor
Carcinogens,Noncarcinogens,AndMixtures”2017
EnvironmentInternational,LesaAylward,Editor,“Ananalysisofcumulativerisksbasedonbiomonitoringdata
forsixphthalatesusingtheMaximumCumulativeRatio”2017
RegulatoryToxicologyandPharmacology,GioBataGori,Editor-in-Chief,“GuidelinesforPerforming
SystematicReviewsintheDevelopmentofToxicityFactors”2017
RiskAnalysis,TonyCox,Editor-in-chief,“CumulativeLow-DoseResponseAssessment:AnAutocorrelatedFirst-
OrderModel”2017
ChemicalResearchinToxicology,F.PeterGuengerich,AssociateEditor,“Identificationofpotentialaryl
hydrocarbonreceptorligandsbyvirtualscreeningofindustrialchemicals"2016
CombinatorialChemistry&HighThroughputScreening,RathnamChaguturu,Editor,“ABigData
ApproachwithArtificialNeuralNetworkandMolecularSimilarityforChemicalDataMiningandIn-SilicoToxicityPrediction”
2016
ScienceoftheTotalEnvironment,Dr.JayGan,Editor,“Occurrence,SourcesandEstimationofAir-SoilExchangeofPolychlorinatedbiphenylsinIndiancities”
2016
ScientificResearchandEssays,Dr.N.J.Tonukari,Editor,“BayesianAnalysistoDetectChange-pointinTwo-PhaseLaplaceModel”
2016
EnvironmentalScienceandTechnology,Dr.BeateEscher,Assoc.Editor,“ToxicogenomicsofDevelopmentalToxicityof6-OH-BDE47inChickenEmbryo"
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2016
EnvironmentalHealthPerspectives,Dr.MartinVandenBerg,Assoc.Editor,“Definingtheneurotoxicpotentialofnondioxin-likepolychlorinatedbiphenylspresentinfishfromUSlakesusingaryanodinereceptor-basedequivalencyscheme”
2016
ScienceoftheTotalEnvironment,Dr.JayGan,Editor,“Occurrence,SourcesandEstimationofAir-SoilExchangeofPolychlorinatedbiphenylsinIndiancities"
2015
Structuredpeerreviewofacomparisonbetweentheeffectsoftobaccosmokeandnicotinevaporfrommodifiedrisktobaccoproductsonthelungsofmice
Answeredaseriesofchargequestionsandalsoprovidedsuggestionforfutureresearch.2015
EnvironmentalHealthPerspectives,Dr.MartinVandenBerg,Assoc.Editor,“Definingtheneurotoxic
potentialofnon-dioxin-likePCBspresentinfishfromUSlakesusingaryanodinereceptor-basedequivalencyscheme.”
2015
IUMBLife,Dr.AngeloAzzi,Editor,“IdentificationofdifferentiallyexpressedthreenoveltranscriptvariantsofmouseArntgene.”
2015
EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Antioxidantactivityasapotentialmechanismexplainingthenegativeinfluenceofleadandcadmiumonworkingmemoryduringaging.”
2015
ToxicologicalandEnvironmentalChemistry,Dr.SamKacew,Editor,“Headspaceandsmallchamberstudiesofairbornediacetylreleasefromselectedfoodflavoringmixtures:Activitycoefficientsandairmodelingimplications”
2015
EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Transcriptomicandvisualgene-networkanalysisofsilvernanoparticlespotentiallyinducedAlzheimer'sdiseaseprogressioninmousebrainneuralcells”
2015
EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“IdentificationofFreePhthalateMetabolitesinHumanCerebrospinalFluid.”
2014
CriticalReviewsinToxicology,Dr.RogerO.McClellan,Editor,“Riskassessmentsforchronicexposureofchildrenandprospectiveparentstoethylbenzene(CASNo.100-41-4)"
2014
EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Impactofearly-lifebisphenolAexposureonprecorticaldopamineandserotoninsystemsinjuvenileandadultmalerats.”
2014
EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“BisphenolAisassociatedwithinsulinresistanceandmodulatesadipokinesgeneexpressioninobesechildren.”
2014
HumanandExperimentalToxicology,Dr.KaiSavolainen,Assoc.Editor,“GlobalMethaemoglobinaemiaResearchOutput(1940–2013):ABibliometricAnalysisBasedonScopusDatabase."
2014
HumanandExperimentalToxicology,Dr.A.WallaceHayes,Assoc.Editor,“PharmacokineticStudyofOmeprazoleanditsMetabolitesinMalesandFemales,FemalesExposedtoHigherLevelsofOmeprazole.”
2013
ConsultationtoaWaterUtilityRegardingtheQualityofWaterProvidedtoaCommunity
Providedinitialconsultationandcoordinatedapeerreviewofariskassessmentofthepesticide
toxapheneoccurringintraceamountsinthewater.2013
HumanandEcologicalRiskAssessment,Dr.BarryJohnson,Editor,“AssessmentofSoilScreeningLevels
duetoAccidentalIngestionofChryseneandBenzo[k]fluorantheneatIran’sTORSite.”2012
HumanandExperimentalToxicology,Dr.A.WallaceHayes,Editor.“Effectofnicotinepre-treatmenton
arsenicinducedoxidativestressinWistarrats."2012
HumanandExperimentalToxicology,Dr.A.WallaceHayes,Editor,“ElementalimpuritiesinNigerian
pediatricsyrups:Mercuryinviolationofstandardguidelines."2011
JournalofToxicologyandEnvironmentalHealth,Dr.SamKacew,Editor,“ScreeningLevelRisk
AssessmentforSANTrimerDetectedinSoilandGroundwater”2011
HumanandEcologicalRiskAssessment,Dr.BarryJohnson,Ed.“MonteCarloSimulation-basedHealth
RiskAssessmentofHeavyMetalPollution-ACaseStudyintheQixiaMiningArea,China”2011
RiskAnalysis,Dr.TonyCox,Editor,“AGradientMarkovChainMonteCarloAlgorithmforComputing
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TedSimon,Ph.D.,DABT Page19of19
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MultivariateMaximumLikelihoodEstimatesandPosteriorDistributions:MixtureDoseResponseAssessment”
2010
EnvironmentalResearch,EllenSilbergeld,Ed.“StructuralNeuroimagingEvaluationofAdultswithChildhoodLeadExposure”
2010
HumanandExperimentalToxicology,Prof.KaiSavolainen,EditorinChief.“TheWorldLibraryofToxicology,ChemicalSafetyandEnvironmentalHealth(WLT)”
2010
JournalofExposureScienceandEnvironmentalEpidemiology,Dr.NatalieFreeman,Assoc.Ed."Comparisonofatoxicokineticandaquestionnaire-basedapproachtoassessmethylmercuryintakeinexposedindividuals”
2010
EnvironmentalResearch,Dr.EllenSilbergeld,Ed.“VaryingcoefficientfunctionmodelstoexploreinteractionsbetweenmaternalnutritionalstatusandprenatalmethylmercurytoxicityintheSeychellesChildDevelopmentNutritionStudy”
2009
RegulatoryToxicologyandPharmacology,GioBattaGori,Ed."DerivedReferenceDoses(RfDs)fortheEnvironmentalDegradatesoftheHerbicidesAlachlorandAcetochlor:ResultsofanIndependentExpertPanelDeliberation"
2009
EnvironmentalResearch,EllenSilbergeld,Ed."EnvironmentalPolicyandChildren'sHealthinMexico"2009
ToxicologicalSciences,Dr.JohnLipscomb,Assoc.Editor,"Age-,Dose-andTime-DependencyofPlasma
andTissueDistributionofDeltamethrininImmatureRats."2009
Chemosphere,HeideloreFiedler,Ed."Quantitativestructure-activityrelationship(QSAR)studiesfor
predictingactivationoftheryanodinereceptortype1channelcomplex(RyR1)bypolychlorinatedbiphenyl(PCB)congeners"
2009
EnvironmentalResearch,EllenSilbergeld,Ed."DeterminationofbromadioloneresiduesinfoxfaecesbyLC/ESI-MSinrelationshipwithtoxicologicaldataandclinicalsignsafterrepeatedexposure.”
2008
Chemosphere,HeideloreFiedler,Ed."TissueDistributionofPolychlorinatedBiphenylsandEffectsonAlaskanNorthernFurSealsAssessedwithFiveCongenerClassificationSchemes"
2008
Chemosphere,HeideloreFiedler,Ed."LevelsofPolychlorinatedDibenzo-p-dioxins,Dibenzofurans,andBiphenylsinSouthernMississippiCatfishandEstimationofPotentialHealthRisks"
2007
CriticalReviewsinToxicology,RogerO.McClellan,Ed.“RiskAssessmentofToxapheneanditsBreakdownProducts:TimeforaChange”
2006
EnvironmentalForensics,IoanaPetrisor,Ed.“IdentifyingMetalsContaminationinGroundwaterUsingGeochemicalCorrelationEvaluation”
2002
EnvironmentalScienceandTechnology,MitchellJ.Small,Ed.“Whyandhowshouldweassessoccupationalhealthimpactsinintegratedproductpolicy?”
2001
OhioEnvironmentalProtectionAgency,“HumanHealthRiskAssessmentConceptPaper”2000
ToxicologyExcellenceinRiskAssessment,“LifetimeEstimateofSkinCancerRiskfromuseofCoalTar
ContainingShampoos”1999
EnvironmentalScienceandTechnology,MitchellJ.Small,Ed.“ChlordaneUptakeanditsTranslocationin
FoodCrops”1997
AgencyforToxicSubstancesandDiseaseRegistry,“PublicHealthInterventionstoPreventorMitigate
PossibleAdverseHealthEffectsRelatedtoMethylParathionPesticideExposure”1995
NationalResearchCouncil,“HumanHealthPreliminaryRiskEvaluationoftheJinkampoIncinerator
ComplexActivitiesintheNavalAirFacility,Atsugi,Japan”