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Novel Technologies to assess Gut Health Claims for Carbohydrates Subthema 1: Synthesis and structural analysis of functional oligosaccharides Name: Prof. Dr. Lubbert Dijkhuizen Affiliation: University of Groningen/ Microbiology Contact: [email protected]
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Synthesis and structural analysis of functional oligosaccharides

Feb 22, 2016

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Novel Technologies to assess Gut Health Claims for Carbohydrates Subthema 1: Synthesis and structural analysis of functional oligosaccharides Name: Prof. Dr. Lubbert Dijkhuizen Affiliation: University of Groningen/ Microbiology Contact: [email protected]. - PowerPoint PPT Presentation
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Page 1: Synthesis and structural analysis of functional oligosaccharides

Novel Technologies to assess Gut Health Claims for Carbohydrates

Subthema 1: Synthesis and structural analysis of functional oligosaccharides

Name: Prof. Dr. Lubbert DijkhuizenAffiliation: University of Groningen/ Microbiology

Contact: [email protected]

Page 2: Synthesis and structural analysis of functional oligosaccharides

Synthesis and structural analysis of functional oligosaccharides

State of the art: Availability CharacterizedFructo-, Galacto-, (Iso)Malto- + +?Xylose-, Pectin-, Mannan-, Chito- (+) (+)??Glucose1,2-1,3-1,4; IMO-MALT (+) -Glucansucrase acceptor products (+) -Plant cell wall oligo’s (+) -Human Milk oligo’s (+) -“CCC new oligo’s” - -

Page 3: Synthesis and structural analysis of functional oligosaccharides

Synthesis and structural analysis of functional oligosaccharides

New technologies:Enzyme discovery and engineering:synthesis of tailor-made oligo’s:

monosaccharides, linkages

Structural analysis:In vitro: newly synthesized oligo’sIn gut: modification, degradation, during passage

Page 4: Synthesis and structural analysis of functional oligosaccharides