日独修好 150 周年記念シンポジウム Symposium to Commemorate 150 Years of German-Japanese Friendship 人類の未来を拓く研究者の グランドチャレンジを支える日独の取り組み Supporting Tomorrow’s Leading Researchers: Innovations and Challenges – Approaches by Japan and Germany – ■開催日時 平成23年7月15日(金) 10:30 – 18:10 レセプション 18:15 – 20:15 ■主 催 ドイツ研究振興協会(DFG)、 ベルリン日独センター(JDZB)、 独立行政法人 科学技術振興機構(JST) ■後 援 文部科学省 ■会 場 日本科学未来館 みらいCANホール(東京都江東区) ■Date / Time Friday, July 15th 2011 10:30 – 18:10 Reception 18:15 – 20:15 ■Organiser German Research Foundation (DFG), Japanese-German Center Berlin (JDZB), Japan Science and Technology Agency (JST) ■Support Ministry of Education, Culture, Sports, Science & Technology (MEXT) ■Venue Mirai CAN Hall, Miraikan (Koto-ku, Tokyo)
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Symposium to Commemorate 150 Years of German · PDF fileSupporting Tomorrow’s Leading Researchers 5 Keynote Speeches Prof. Dr. Tasuku HONJO Executive Member of the Council for Science
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日独修好 150 周年記念シンポジウム
Symposium to Commemorate 150 Years of German-Japanese Friendship
人類の未来を拓く研究者のグランドチャレンジを支える日独の取り組み
Supporting Tomorrow’s Leading Researchers:Innovations and Challenges
10:30-10:50 Opening RemarksProf.Dr.KoichiroAGATA ▶ Member of the Foundation Council of JDZB,
Professor, Waseda Okuma School of Public Management, Waseda University
Prof.Dr.-Ing.MatthiasKLEINER ▶ President of the DFG
Prof.D.Sc.KoichiKITAZAWA ▶ President of the JST
10:50-11:10 Greetings from Guests
Prof.Dr.TasukuHONJO ▶ Executive Member of the Council for Science and Technology Policy (CSTP)
MEXTRepresentative
Mr.PeterRONDORF ▶ Minister and Head of the Economic and Science Department, Embassy of the Federal Republic of Germany
11:10-12:00 Keynote Speeches
Prof.Dr.h.c.mult.JörgHACKER ▶President of the German National Academy of Sciences Leopoldina
Prof.Dr.YoshihiroKAWAOKA ▶ Professor, International Research Center for Infectious Diseases and Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Japan
12:00-13:30 Lunch
13:30-15:00 Successful Innovative Research and High-Risk Research Funding
Prof.Dr.-Ing.MatthiasKLEINER ▶ President of the DFG
Prof.D.Sc.KoichiKITAZAWA ▶ President of the JST
Prof.Dr.HiroshiTAKAHASHI ▶ Director, JST Program Officer Academy, Principal Fellow, Department of Personnel
15:00-15:30 CoffeeBreak
15:30-18:00 Examples of Innovative Research Activities. How Early Career Researchers Can Address the Challenges of Shaping the Science and Society of Tomorrow
15:30-16:10 Session I: Solar Energy Conversion and UseProf.Dr.HaruoINOUE ▶ Professor, Center for Priority Area, Tokyo Metropolitan University,
Research Supervisor of PRESTO ("Sakigake") Project "Chemical Conversion of Light Energy"
Dr.RyuABE ▶ Associate Professor, Catalysis Chemistry Research Centre, Hokkaido University, Group Leader for Research Cluster of Functionalized Crystals
Prof.Dr.Hans-WernerSCHOCK ▶ Director of Institute Technology, Helmholtz Center Berlin for Materials and Energy, Speaker of Division Solar Energy
16:10-16:40 Session II: Innovations in Medical TreatmentDr.KenjiOSAFUNE ▶ Associate Professor, Center for iPS cell Research and Application (CiRA), Kyoto University,
JST PRESTO ("Sakigake") Researcher (Project "Understanding Life by iPS Cells Technology")
Prof.Dr.IleanaHANGANU-OPATZ ▶ Professor, Dev. Neurophysiology, Center for Molecular Neurobiology, University Medical Center Hamburg-Eppendorf, Emmy Noether Independent Research Group Leader
16:40-17:10 Session III: The Development of Nanobiology CapabilityProf.Dr.TakeharuNAGAI ▶ Professor, Research Institute for Electronic Science, Hokkaido University,
JST PRESTO ("Sakigake") Researcher (Project "Innovative Use of Light and Materials / Life")
Prof.Dr.ChristianHACKENBERGER ▶ Professor of Bioorganic Chemistry, Institute for Chemistry and Biochemistry, Free University of Berlin, Emmy Noether Independent Research Group Leader
Prof. Dr. Koichiro AGATAMemberoftheFoundationCouncilofJDZB,Professor,WasedaOkumaSchoolofPublicManagement,WasedaUniversity
Prof.Dr.KoichiroAgataisamemberoftheFoundationCounciloftheJapanese-GermanCenterBerlin (JDZB).Hestudiedpoliticalscienceat Waseda University (M.A. 1982) and received his Ph.D. from theHochschule für Verwaltungswissenschaften in Speyer in PublicAdministration. He joined Waseda University as research associatein1982andbecameprofessor forpublicadministration in1997. In
2003hebecameprofessor for public administration at theWasedaOkuma School of Public Management, where he served as dean2008-2010.Since2008heistheAlexandervonHumboldtFoundationAcademicAmbassador inJapan. In2008healsowasappointedasMEXTScienceCounsellor,and2011hebecameaCommissionerforLegal System of Intelligence Services. Prof. Agata received variousscholarships,amongstothers from theGermanAcademicExchangeService and the Alexander von Humboldt Foundation. He also wasawardedwiththeVerdienstkreuzamBandedesVerdienstordensderBundesrepublikDeutschland (OrderofMeritof theFederalRepublicofGermany).
Prof. Dr.-Ing. Matthias KLEINERPresidentoftheDFG
Prof. Dr.-Ing. Matthias Kleiner is the President of the DeutscheForschungsgemeinschaft (DFG, German Research Foundation), thecentralself-governingresearchorganization thatpromotesresearchat universities and other publicly funded research institutions inGermany.He isanengineeringscientist,andwaselectedPresidentfor a three-year term by the DFG's General Assembly on 31 May2006. Professor Kleiner has taken office on 1 January 2007. On 1July2009hewaselectedforasecondterm.Asaproductionscientist,Matthias Kleiner combined novel manufacturing technologies with
theintegrativecross-topicoflightweightconstruction.Hehasplayedan instrumental role in a number of international, and above allinterdisciplinary,researchprojectsandresearchnetworks.ProfessorKleiner is a member of numerous professional committees andacademies, including the Berlin-BrandenburgAcademy of Sciencesand Humanities; acatech – the German Academy of Science andEngineering; theGermanAcademyofNaturalScientistsLeopoldina;andAcademiaEuropaea.From2007until2010hewasVice-PresidentoftheEuropeanScienceFoundation(ESF).InrecognitionofhismeritsforGermanScience,hewasawardedtheOfficer’sCrossoftheOrderofMeritoftheFederalRepublicofGermanyin2010.
Prof. D.Sc. Koichi KITAZAWAPresidentoftheJST
1966 BSfromUniversityofTokyo,DepartmentofChemistry1972 D.Sc. from Department of Materials Science and Metallurgy,
MIT1972 DSRstaff,CeramicsDivision,MIT1973 Research Associate, Dept. of Synthetic Chemistry, Univ. of
The symposium is jointly organised by the German Research Foundation(DFG),theJapanese-GermanCenterBerlin(JDZB)andtheJapanScienceandTechnology Agency (JST) to celebrate the 150th anniversary of the Japan-GermanTreatyofAmity.Thesymposiumwilladdresshowcollaborationsandinnovations in science can be better promoted and their impact on societybetter communicated to a broader public, includingpoliticians, the scientificcommunityandthemedia.Therewillbeopendiscussionson• practical approaches to support the next generation of outstanding
researchers;• essentialfunctionsofresearchfundingsystems;• challengesforkeyplayers;• collaborative opportunities in science and society between Germany and
Japan.
Introduction
Supporting Tomorrow’s Leading Researchers 5
Keynote Speeches
Prof. Dr. Tasuku HONJOExecutive Member of the Council for Science andTechnologyPolicy(CSTP)
Since2005ProfessorattheDepartmentofImmunologyandGenomicMedicineattheKyotoUniversityGraduateSchoolofMedicine;since2006ExecutiveMember of theCouncil forScienceandTechnologyPolicy,CabinetOffice,Japan.He was a fellow of Carnegie Institution of Washington (Baltimore,Maryland) and a visiting fellow and associate at the Laboratoryof Molecular Genetics at the National Institute of Child Health andHumanDevelopment,NIH(Bethesda,Maryland).From1999to2003heworkedasScienceAdvisorfortheMinistryofEducation,Culture,
Sports, Science and Technology (MEXT); from 2002-2004 he wasDeanoftheFacultyofMedicineatKyotoUniversity;from2004to2006heworkedasDirectoroftheResearchCenterforScienceSystemsattheJapanSocietyforthePromotionofScience(JSPS).He received the following awards: Noguchi Hideyo-MemorialAwardfor Medicine,Asahi Prize, Osaka Science Prize, Kihara Prize of theJapanese Genetics Society, Erwin von Baelz Prize, Takeda MedicalPrize,Behring-KitasatoPrize,UeharaPrize,TheImperialPrize,JapanAcademy Prize, and the Award “Persons of Cultural Merit” by theJapaneseGovernment.HeisaForeignAssociateoftheU.S.NationalAcademyofSciences,and a member of Leopoldina (The German Academy of NaturalScientists)andofJapanAcademy.
Mr. Peter RONDORFMinisterandHeadoftheEconomicandScienceDepartment,EmbassyoftheFederalRepublicofGermany
1985 FirstSecretary(politicalsection),GermanEmbassyTokyo,Japan1988 DeskOfficer,divisionforexportpromotionintheForeignOffice1990 Head of economic services, German Embassy Islamabad,
Pakistan1992 DeputyHeadofMission,GermanEmbassyRiga,Latvia1996 Deputy Head of division in the European Department of
the Foreign Office, concerned with issues of economic andmonetaryunion
1999 Deputy Head of Mission, German Embassy Kuala Lumpur,Malaysia
Japan-German Cooperation in Science – Microbiology as an example
TherelationshipandcollaborationbetweenscientistsofJapanandGermanyinthefieldoflifescienceshasalongtradition.FriedrichFranzvonSiebold,forinstance,wasoneofthefirstEuropeantoteachclinicalmedicineinJapaninthemiddleofthe19thcenturyandamongEuropeanacademicsisregardedasthe“ScientificDiscoverer”ofJapan.AnexampleforastillexistingtightrelationshipbetweenJapaneseandGermanmicrobiologiststracesbacktoShibasaburoKitasatoandRobertKoch.Kitasato,whowasastudentofRobertKoch,workedinBerlininthe80´sand90´softhe19thcenturyand,afterhisstayinBerlin,establishedaschoolforinfectiousdiseasesinJapan,andlatertheKitasotoInstitute.Todaytherestill isaverylivelyandfruitfulscientificexchangebetweenbothcountriesandmanyongoingexcellentand innovativecollaborativeresearchactivities in thefieldsofmicrobiology,infectionbiologyandclinicalmedicinewillcontinuetodrivetheprogressinthedevelopmentofnoveltechniquesforfutureresearchandtherapeuticapplications.
Prof. Dr. h.c. mult. Jörg HACKERPresident of the German National Academy ofSciencesLeopoldina
JörgHackerobtainedhisPhDinBiologyfromtheUniversityofHalle(Saale) in 1979. He went on to becomeAssociated Professor forMicrobiologyattheUniversityofWürzburgin1988,wherehewasFullProfessorandDirectorof the Institute forMolecular InfectionBiologyfrom1993to2008.Hisresearchfocusesonthemolecularanalysis of infectious bacteria and of host-pathogen interactions.Hackerwasavisiting researcherat the InstitutePasteur in2000
and2005,andwasaguestprofessoratTelAvivUniversityin2006.In2003-2009HackerwasVicePresidentoftheGermanResearchFoundation(DFG),andin2008-2010PresidentoftheRobertKochInstitute in Berlin. Since March 2010 he is the President of theGerman NationalAcademy of Sciences Leopoldina. In 2011 JörgHacker was appointed foreign scientific member of the Max-Planck-Society
Representative from the MEXT
Greetings from Guests
Supporting Tomorrow’s Leading Researchers6
Successful Innovative Research and High-Risk Research Funding – Speakers
Dr.YoshihiroKawaokaobtainedhiseducation inJapan, receivinghisDVMin1978andhisPh.D. in1983fromHokkaidoUniversity.Early in his career, he identified the critical determinant for highpathogenicity of avian influenza viruses; this information is nowusedbytheUSDAandOrganisationMondialedelaSantéAnimale(WorldOrganisationforAnimalHealth,OIE)asacriterionforrapidly
identifying lethal and non-lethal bird flu viruses. Dr. Kawaokaalso established reverse genetics, which allows the generationof ‘designer’ influenza viruses. This technology – coupled withknowledge he established regarding the attenuation of deadlyinfluenzaviruses–wasexploitedinthedevelopmentofcandidateH5N1 influenza virus vaccines, which were proven efficacious inclinical trials. Dr.Kawaokahasalsoundertaken thestudyof the1918 Spanish flu virus, which killed over 40 million people. Hedetermined that infectionby the1918virus causedanabnormalimmuneresponse.InformationuncoveredbyDr.Kawaokaisusedgloballybypublichealthagenciesastheyundertaketheenormoustaskofinfluenzapandemicplanning.
Funding isessential to research.As fundsbecome increasing limited,how fundingorganizationsallocate this scarce resourcehasanenormousimpactonfutureresearch.Bothfundingorganizationsandawardeesneedtobeawareofeachother'sgoalsandtorecognizetheirsharedpurpose–toproduceknowledgethatbenefitsthehumanrace.
Prof. Dr.-Ing. Matthias KLEINERPresidentoftheDFG
Prof. Dr.-Ing. Matthias Kleiner is the President of the DeutscheForschungsgemeinschaft (DFG, German Research Foundation),the central self-governing research organization that promotesresearch at universities and other publicly funded researchinstitutions in Germany. He is an engineering scientist, and waselected President for a three-year term by the DFG's GeneralAssembly on 31 May 2006. Professor Kleiner has taken officeon1January2007.On1July2009hewaselectedforasecondterm.As a production scientist, Matthias Kleiner combined novel
manufacturing technologies with the integrative cross-topic oflightweight construction.Hehasplayedan instrumental role in anumber of international, and above all interdisciplinary, researchprojectsandresearchnetworks.ProfessorKleinerisamemberofnumerous professional committees and academies, including theBerlin-BrandenburgAcademyofSciencesandHumanities;acatech– theGermanAcademyofScienceandEngineering; theGermanAcademyofNaturalScientistsLeopoldina;andAcademiaEuropaea.From 2007 until 2010 he was Vice-President of the EuropeanScienceFoundation(ESF). InrecognitionofhismeritsforGermanScience,hewasawardedtheOfficer’sCrossoftheOrderofMeritoftheFederalRepublicofGermanyin2010.
Present: GuestProfessorofKougakuinUniversityinTokyoandKunming University of Science and Technology inChina.
3.PublicationsSix books, sixty-five reviewed academic articles, forty-one non-reviewedacademicarticleswerepublished in the research fieldsof radiochemistry, space science, optical telecommunication,environmentandenergy.
Management of High-Risk and High-Impact Research Funding at JST
Prof. Dr. Haruo INOUEProfessor,CenterforPriorityArea,TokyoMetropolitanUniversity,ResearchSupervisorofPRESTO("Sakigake")Project"ChemicalConversionofLightEnergy"
Dr. Haruo Inoue was born in 1947 in Japan. He graduated fromtheUniversityofTokyoin1969.Afterfinishingthegraduatecourseof theUniversityofTokyo,he joined the facultyofDepartmentofApplied Chemistry at Tokyo Metropolitan University in 1972. HereceivedtheJapanesePhotochemistryAssociationAwardin1997andMukaiAwardin2011.CurrentlyheisaprofessoroftheCenterofPriorityAreaatTokyoMetropolitanUniversity.HehasalsoservedastheVicePresidentoftheChemicalSocietyofJapan(2004-2006),thePresidentof theJapanesePhotochemistryAssociation (2006-
2007),andthePresidentoftheAsianandOceaniaPhotochemistryAssociation (2008-2010). He has been an editor-in-chief ofJournal of Photochemistry and Photobiology, C, PhotochemistryReviews and on the advisory board of Langmuir, in addition tothree other international journals. His major research interestsare photochemistry, energy coupling among chemical reactions,selective energy flow in solution, anisotropic control of chemicalreactions in the excited state, nano-layered compounds, metalcomplexes, artificial photosynthesis, etc. He has been a projectleader of Core Research on Evolutional Science and Technology(CREST and SORST) under auspices by Japan Science andTechnologyAgency(JST)ontheresearchsubjectof“ConstructionofArtificialPhotosynthesiswithWaterasanElectronSource.”HehasalsoservedastheresearchsupervisorofPRESTOproject(JST)on“Chemicalconversionoflightenergy.”E-mail:[email protected]
Dr. Iris WIECZOREKDirectoroftheDFGOfficeJapan
SinceFebruary2009directoroftheDFGOfficeJapan.ShestudiedJapaneseandChineseStudies,andComputerScienceattheUniversityofHamburg.Shegraduatedin1996andreceivedherPhDofphilosophyin2000fromtheUniversityofHamburg.Duringhergraduate and doctoral studies, she lived in Japan for several yearsanddidfieldresearch.From2000to2008sheworkedasaResearchFellow at the GIGA Institute ofAsian Studies in Hamburg and as aResearchManagementOfficeratGIGAsince2005.Hermajorresearchinterestswereinnovationprocessesandnetworks
in the Japanese economy and society, social movements, therelationship between politics and religion in Japan in internationalcomparison. She published numerous papers on the Japaneseinnovation system in international comparison. She is co-editor oftheYearbookJapan–Wirtschaft,PolitikundGesellschaft [economy,politicsandsociety]. Shegaveregularcoursesat theAsian-Africa-InstituteoftheUniversityofHamburg.
Session I: Solar Energy Conversion and Use – Speakers
Successful Innovative Research and High-Risk Research Funding – Moderator
Supporting Tomorrow’s Leading Researchers 9
Dr. Ryu ABEAssociateProfessor,CatalysisChemistryResearchCentre,HokkaidoUniversity,GroupLeaderforResearchClusterofFunctionalizedCrystals
Ryu Abe received his BS (1996), MS (1998) and PhD (2001)degrees fromTokyo Institute ofTechnology. He then worked asa postdoctoral fellow (2001-2002) and as a researcher (2002-2005) at the National Institute of Advanced Industrial Science
andTechnology (AIST), Japan. In 2005, his academic career asan Associate Professor began at the Catalysis Research Center,Hokkaido University. After studying as a research fellow of thePRESTO/JSTprogram,(ChemicalConversionofLightEnergy)from2009to2011,hestartedaresearchprogramwiththesupportofFundingProgramforNextGenerationWorld-LeadingResearchers(NEXT Program) from 2011. His research is mainly focused onthe development of new photocatalysts for water splitting andenvironmentalpurification.
Development of a New Photocatalytic Water Splitting System toward Solar Hydrogen Production
Prof. Dr. Hans-Werner SCHOCKDirectorof InstituteTechnology,HelmholtzCenterBerlinforMaterialsandEnergy,SpeakerofDivisionSolarEnergy
Prof. Dr. Hans-Werner Schock received his diploma in electricalengineeringin1974andobtainedhisPh.D.inelectricalengineeringfrom Stuttgart University, Germany, in 1986. From 1982 to 2004he was head of the compound semiconductor thin film group ofthe Institute of Physical Electronics at the University of Stuttgartwhere he guided the research on thin film photovoltaics andelectroluminescence. Starting in the early 70s, he has taken the
developmentofchalcogenidesolarcellsfrombasicinvestigationsto the transfer to pilot fabrication. From 1986 to 2003 hecoordinated the researchonchalcopyritebasedsolarcells in theframeworkoftheEuropeanphotovoltaicprogram.Hebecameheadof the InstituteofTechnologyat theHelmholtzZentrumBerlin fürMaterialien und Energie (former Hahn-Meitner Institute) in thedivision"SolarEnergyResearch"inlate2004.Heisauthororco-authorofmorethan300contributionsinbooks,scientificjournalsand published conference proceedings. For his achievements inthedevelopmentofchalcopyritebasedsolarcellshereceivedtheprestigious"BecquerelPrize"oftheEuropeanCommissionin2010.
Potential and Challenges for Research on Photovoltaics as a Future Energy Source
Session II: Innovations in Medical Treatment – Speakers
Melody of the Neonatal Brain: Maturation of Neuronal Networks and Behavioral Abilities as Result of Early Oscillatory Activity
Co-activationofneuronalassembliesbysynchronizingtheiractivitypatternsinoscillatoryrhythmsenablessensoryperception,attentionandmemory.Theabilitytogenerateoscillatoryrhythmsisnotahallmarkoftheadultbrain,butispresentalreadyduringearlydevelopment.Synchronizedpatternsofoscillatoryactivityarepresentinthesensory(visual,somatosensory)corticalareasofbothprematureinfantsandneonatalrodentsandaretriggeredbyendogenousactivationofsensoryperipheryandintracorticalactivation.Ourexperimentaldatasuggestthattheseearlyoscillationsactastemplatefacilitatingtheestablishmentofcorticalmaps,whicharerequestedforsensoryprocessing.Ontheotherhand,thedevelopmentofprefrontal-hippocampalnetworks,whichenablecognitiveprocessing,seemstobeequallycontrolledbytheearlyoscillatoryactivity.Combininginvivoelectrophysiologyandpharmacologywithimmunohistochemistryandbehavioraltesting,werecentlydemonstrated thatnetworkactivity in thehippocampusdrives theactivationof thedevelopingprefrontalcortex.Theearlyprefrontal-hippocampal network is subject of intense cholinergic modulation in relationship with the emergence of cognitive abilities.Miswiringwithinthedevelopingprefrontal-hippocampal-subcorticalnetworkduetoabnormalpatternsofearlyactivityandsynchronizationmayaccountforspecificmnemonicandexecutiveimpairmentthathasbeenreportedforseveralneurodevelopmentaldisorders.
Prof. Dr. Ileana HANGANU-OPATZProfessor,Dev.Neurophysiology,CenterforMolecularNeurobiology,UniversityMedicalCenterHamburg-Eppendorf,EmmyNoetherIndependentResearchGroupLeader
Educationandprofessionalexperience1994-1998 Studies of Biology and Biochemistry, University of
Bucharest,Romania1997-1998 Diploma thesis at University Medical Center
Dr. Kenji OSAFUNEAssociateProfessor,Center for iPScellResearchandApplication(CiRA),KyotoUniversity,JST PRESTO ("Sakigake") Researcher (Project"UnderstandingLifebyiPSCellsTechnology")
Kenji Osafune is a Principal Investigator of Center for iPS CellResearchandApplication(CiRA),KyotoUniversity,Kyoto,Japan.HereceivedhisM.D.degreefromFacultyofMedicine,KyotoUniversityin1996,completedhis residency inNephrologyandobtainedhisPh.D. degree in Developmental biology from University of Tokyo,
(Tokyo), Japan in 2003. Dr. Osafune subsequently completed apostdoctoral fellowship with Professor Doug Melton at HarvardUniversityin2008.Currently,hisresearchgroupisworkingonthetargeteddifferentiationofhumanembryonicstemcells(ESCs)andinduced pluripotent stem cells (iPSCs) into kidney, pancreas andliverlineagesthatmayallowtheexploitationofhumanstemcellsforregenerativemedicinestrategyagainstchronickidneydisease,diabetes mellitus and chronic liver disease. His interest alsoincludesthedevelopmentof iPSCsasmodelsofhumandiseasesand chemical biology that regulates the differentiation of humanstem cells and prevents the progression of pathology of humandiseases.
Supporting Tomorrow’s Leading Researchers 11
Session III: The Development of Nanobiology Capability – Speakers
Prof. Dr. Takeharu NAGAIProfessor,ResearchInstituteforElectronicScience,HokkaidoUniversity,JST PRESTO ("Sakigake") Researcher (Project"InnovativeUseofLightandMaterials/Life")
In 1998, I received Ph.D. from Medical Science Department inthe University of Tokyo, and moved to Brain Science Institute,RIKEN to work on the GFP technology in Miyawaki’s laboratoryas a postdoctoral researcher. My first work in the laboratorywas the invention of “pericam”, a Ca2+ indicator based on acircularly permuted green fluorescent protein (PNAS 2001). In2001, I becameaPRESTO researcher by granting fromJST, and
then published representative papers concerning invention oftwo fluorescent proteins, Venus, the brightest version of yellowfluorescentprotein(NatureBiotechnol.2002),andcameleon3.60,agenetically-encodedCa2+indicatorbasedonFRETwiththebiggestdynamicrange(PNAS2004).InJanuary2005,ImovedtoResearchInstituteforElectronicScience,HokkaidoUniversityasaProfessor.Currently,mylaboratoryisworkingoninventingnovelbio-imagingtechnologies.Recentinventionsareaphotoconvertiblefluorescentprotein,Phamret(NatureMethods2008),aultramarinefluorescentprotein,Sirius (NatureMethods2009),achemiluminescentCa2+indicator, BRAC (PLoS One 2010), and a ultrasensitive Ca2+indicator,yellowcameleonNano(NatureMethods2010). In2008,I became a PRESTO researcher again and am struggling towardinventionofhighluminescentnanolightsourcesforlifescience.
Toward Invention of High Performance Genetically-Encoded luminescent Indicators for Functional Imaging in Living Organisms
[1] a) J. A. Prescher, C. R. Bertozzi, Nat. Chem. Biol. 2005, 1, 13. b) C. P. R. Hackenberger, D. Schwarzer, Angew. Chem. Int. Ed. 2008, 47, 10030.
[2] R. Serwa, I. Wilkening, G. del Signore, M. Mühlberg, I. Claußnitzer, C. Weise, M. Gerrits, C. P. R. Hackenberger, Angew. Chem. Int. Ed. 2009, 48, 8234.
Prof. Dr. Christian HACKENBERGERProfessorofBioorganicChemistry,InstituteforChemistryandBiochemistry,FreeUniversityofBerlin,EmmyNoetherIndependentResearchGroupLeader
Prof.Dr.ChristianP.R.Hackenberger,born in1976 inOsnabrück(Germany), studiedchemistry inFreiburgandat theUniversityofWisconsin/Madison(MScin1999withSamuelH.Gellman).In2003he completed his PhD with Carsten Bolm at the RWTH Aachen.AfterpostdoctoralresearchwithBarbaraImperiali(2003–2005)attheMassachusetts Institute ofTechnologyhemoved to the FreieUniversitätBerlin,wherehefirstledanEmmy-Noetherjuniorgroupfrom 2006-2010. In 2011 he was then appointed professor of
bioorganicchemistry.Since2008hehasbeenspokesmanof thegraduate college “Mulitvalency in chemistry and biochemistry”withinSFB765andsince2011thespokesmanoftheCoordinatedPriority Program “Chemoselective Reactions for the Synthesisand Application of Functional Proteins”. Recently, ChristianHackenbergerhasbeen the recipient of several researchawardsincludingin2011theHeinzMaier-LeibnitzPrizeoftheDFGaswellastheADUCpriceoftheGDCh. Intotal,Hackenbergerhasraisedmorethanthreemillioneurosinexternalfundingsince2005.The scientific research interests of Prof. Hackenberger focus onvarious areas in chemical biology, including the developmentof chemoselective reactions, protein semi-synthesis, design ofmultivalentscaffolds,cyclicproteins,biosynthesisofsialicacidsaswellasthestructuralandfunctionalanalysisofproteinmodificationsincludingsignaltransductionandproteinaggregation.
Withthebudgetofabout$1.4billion(FY2011,1USD=82JPY),JSTimplementstheScienceandTechnologyBasicPlanofthegovernmentofJapan,comprehensivelysupportingtheentire innovationprocessfromthecreationofknowledge to the practical application of research achievements in society. In addition, JST promotesdisseminationofscientificandtechnological information,sciencecommunication,andsupportof internationalresearchcooperation.
TheDFGistheself-governingorganisationforscienceandresearchinGermany.Itservesallbranchesofscienceandthehumanities.TheDFGisanassociationunderprivate law. ItsmembershipconsistsofGermanresearchuniversities,non-university research institutions,scientificassociationsandtheAcademiesofScienceandtheHumanities.TheDFGreceivesthelargemajorityof itsfundsfromthestatesandtheFederalGovernment,whichare represented inallGrantsCommittees.At thesame time, thevotingsystemandprocedural regulationsguaranteescience-drivendecisions.ThechieftaskoftheDFGistoselectthebestresearchprojectsbyscientistsandacademicsatuniversitiesandresearch institutionsonacompetitivebasisand to finance theseprojects.Projectsarepresentedbyscientistsandacademicsorbyuniversities inaproposal,which is thenevaluatedbyvoluntaryreviewersexclusivelyaccordingtoscientificcriteria.DFGfundingguaranteesquality-baseddifferentiationintheGermanresearchsystem.
TheFoundationwasestablishedonJanuary15,1985,byaproposalputforwardbythethenheadsofgovernmentof theFederalRepublicofGermanyandJapan,HelmutKohlandNakasoneYasuhiro. Its task issetout in theFoundationCharter:“…topromoteanddeepenJapanese-Germanand internationalcooperation inthefieldsofscienceandcultureanditsconnectiontoeconomiclife.”