Supersecondary Structure. Sidechain - Sidechain interactions.

Supersecondary Structure

Sidechain - Sidechain interactions

Topology Diagrams

Page 24

Hairpin LoopsPage 21

Alpha – Beta Structures

Page 24

Helix – Loop – Helix Page 25

Calcium Binding MotifPage 25

Calcium Binding MotifPage 26

Coiled – coil structure

Two alpha helices are intertwined and coil around each other

Page 35

Coiled-coil alpha helixPage 36

Stabilization of a coiled-coilPage 37

Domains and Quaternary Structure

Four Helix Bundle

Page 38

Examples of four helix

bundles

Page 38

The globin domain

Page 40

Tyrosyl-tRNA synthetase

domain structure

Page 59

Influenza virus neuraminidase

domainsPage 71

Neuraminidase is a tetramer

Page 72