Superior wound closure 1. Chee SP. Clear corneal incision leakage after phacoemulsification–detection using povidone iodine 5%. Case Report. Int. Ophthalmology 2005 Aug-Oct:26:175-179. 2. Mifflin MD, Kinard, K, et al. Comparison of Stromal Hydration Techniques for Clear Corneal Cataract Incisions: Conventional Hydration versus Anterior Stromal Pocket Hydration. Journal of Refractive Surgery. 2012 Jun; 38(6):933-937. 3. Herretes S, Stark WJ, et al. Inflow of ocular surface fluid into the anterior chamber after phacoemulsification through sutureless corneal cataract wounds. American Journal of Ophthalmology. 2005;140;737-740. 4. Masket S, Hovanesian J, et al. Use of a calibrated force gauge in clear corneal cataract surgery to quantify point-pressure manipulation. J Cataract Refract Surg. 2013 Feb 21. 0% 20% 40% 60% 80% 100% Spontaneous leak Spontaneous or with minimal touch (ч0.25 ozf) 50.0% (244/488) 76.0% (371/488) Cumulative leak rates prior to device placement* Clear corneal incisions leak Propensity for leakage has been demonstrated in several additional studies. 1-4 Challenges or forces on the eye, such as touching or sneezing, may promote leaks. More protection should be administered for vulnerable wounds. Superior to sutures for prevention of wound leaks 0% 10% 20% 30% 40% ReSure Sealant Suture Per protocol leak rates following device placement* 4.1% (12/295) 34.1% (60/176) p<0.0001 Significantly fewer adverse events in the ReSure group vs. the suture group (p<0.0001). 94.1% of sealant cases were rated “easy” or “very easy” to use. No safety concerns were reported. Patients were comfortable overall. * ReSure Sealant Pivotal Clinical Trial results. Ocular Therapeutix Inc., data on file. Effectively seals clear corneal incisions Safe and comfortable for the patient