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Dr. D. Y. Patil Unitech Society's, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune – 411018 RECOMMENDATIONS/ SUGGESTIONS COMMUNICATED TO AFFILIATING UNIVERSITY (SPPU) AND ACTION TAKEN FOR B. PHARM & M. PHARM 2018 – 2019
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Page 1: suggestions communicated to affiliating university (sppu) and ...

Dr. D. Y. Patil Unitech Society's,

Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research,

Pimpri, Pune – 411018

RECOMMENDATIONS/ SUGGESTIONS

COMMUNICATED TO AFFILIATING

UNIVERSITY (SPPU) AND ACTION TAKEN

FOR B. PHARM & M. PHARM

2018 – 2019

Page 2: suggestions communicated to affiliating university (sppu) and ...

Sr. No. Particulars of document

1. Communication of subject teacher with HODs and

recommendations/suggestions for subject redesigning (Department of

Pharmaceutical Chemistry) 2018 - 2019

Communication of subject teacher with HODs

(Subject – Pharmaceutical Inorganic Chemistry, B. Pharm)

Recommendations - (Subject – Pharmaceutical Inorganic Chemistry, B. Pharm)

Communication of subject teacher with HODs

(Subject – Pharmaceutical Organic Chemistry, B. Pharm)

Recommendations (Subject – Pharmaceutical Organic Chemistry, B. Pharm)

Communication of subject teacher with HODs

(Subject – Pharmaceutical Analysis I & Biochemistry, B. Pharm)

Recommendations (Subject – Pharmaceutical Analysis I, B. Pharm)

Recommendations (Subject –Biochemistry, B. Pharm)

Recommendations (Subject – Pharmaceutical Organic Chemistry - II, B. Pharm)

Recommendations (Subject – Pharmaceutical Organic Chemistry III, B. Pharm)

2. Communication of HOD with BOS Chairman (Department of Pharmaceutical

Chemistry) 2018 - 2019

Communication (B. Pharm & M. Pharm)

3. Communication of BOS chairman with Academic board, SPPU (Department of

Pharmaceutical Chemistry) 2018 – 2019

FY B. Pharm

SY B. Pharm

M. Pharm

4. Action taken by University (Department of Pharmaceutical Chemistry) 2018 –

2019

Revised syllabus copy (Subject – Pharmaceutical Inorganic Chemistry, B. Pharm)

Revised syllabus copy (Subject – Pharmaceutical Organic Chemistry, B. Pharm)

Revised syllabus copy (Subject – Pharmaceutical Analysis I, B. Pharm)

Revised syllabus copy (Subject –Biochemistry, B. Pharm)

Revised syllabus copy (Subject – Pharmaceutical Organic Chemistry - II, B. Pharm)

Revised syllabus copy (Subject – Pharmaceutical Organic Chemistry - III, B. Pharm)

5. Recommendations/suggestions from HODs for subject redesigning (Department

Page 3: suggestions communicated to affiliating university (sppu) and ...

of Pharmaceutics) 2018 - 2019

M. Pharm (Subject – Modern Pharmaceutics)

M. Pharm (Subject – Pharmaceutics Practical Sem II)

6. Communication of HOD with BOS Chairman (Department of Pharmaceutics)

2018 - 2019

M. Pharm

7. Action taken by University (Department of Pharmaceutics) 2018 – 2019

Revised syllabus copy (Subject – Modern Pharmaceutics)

Revised syllabus copy (Subject – Pharmaceutics Practical Sem II)

8. Recommendations in Pharm D syllabus 2018- 2019

Page 4: suggestions communicated to affiliating university (sppu) and ...

2310512022,13:39 Dr. D.Y. Patil Unitech Society Mail - Syllabus modification points

Syllabus modification points1 message

Sneha R. Chandani Pharmaiy <[email protected]>To: "Mrs. Asha Thomas Pharmacy', <[email protected]>

Respected mam

PFA. Please suggest if any changes are required.

ffi i;il" for syllabus modification.docx

Dr. D, v. *tirprr.,il,,Iutii;,FJffilf 1".9,*

Pimpri, pune+rf df'e.

30 March 2019 at 10:51

hftps://maif.google.com/mail/u/0t?ik=a}1d5402a4&view=pt&search=all&permthid=thread-a%34r-614.1110733470500411&simol=mso_aol^3 Af_75,11 ,tr.l

Page 5: suggestions communicated to affiliating university (sppu) and ...

BP104T PHARMACEUTIcAL I NoRGAN tC CH EM tsTRy(Theory)

Suggestions:

o waters in Pharmacy may be included the syllabus. (They will read-preparation of purified waterand water for injection BP by distillation in Pharm Engineering Theory and perform

Bacteriological analysis of water in Microbiology practicar)

r (Unit lll) Antimicrobials is a separate chapter so may be bulleted separatelyo (Unit lll) Cathartics- Kaolin and Bentonite are not used as cathartics but protectives, separate

tab may be created for these two.o (Unit lV)Typographical error- Remove 333 after sodium nitrite

BP110P. PHARMACEUTTcAL I NORGAN rc cH EMrsrRy (practica t)

Suggestions:

Determination of potassium iodate and iodine in potassium lodide

BP202T . PHARMACE UTt cAL O RGAN I c CH E M tSTRy _t (Th eory)

No suggestions

BP2O8P. PHARMACEUT]CAL ORGANIc cHEMISTRY -I (Practical)

concept of binary mixture.separation may be introduced ( t or 2 exercises)

Construction of stereomodel may be shifted to second year as stereochemistry in a part of 2no yearsyllabus. ( The excercises related to D/L, R/S, conformational isomers is not possible if kept in first year)

Lrr,rs.s (C!^u^dad)

Page 6: suggestions communicated to affiliating university (sppu) and ...

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Page 7: suggestions communicated to affiliating university (sppu) and ...

5114122, 12 50 PM Dr U Y Patrl Unitech Socrety Marl - Fw Fwd tlegardrnq PCI Syllabrrs 2018 Pattern Sublect POCI

FKOM IUE] X,I IACAEry.rs. Asha Thomas Pharmacy <asha'thomas@dypvp'edu'in>

MtrMBtrR] LD\S-L0nE.... E..,-r. Etaaarr{inn pct -Srrltahus 2|lSPattern Subiect: POCI g'Pl++kMFw: Fwd: Regarding PCI Sylf abus 2018 Patterrt Subject:

sneha R. Chandani Pharmacy <[email protected]>

To: "Mrs. Asha Thomas PharmaCy" <asha'thomas@dypvp'edu in>

1)UNIT-l; Structural isomerisms in organic compounds

Stereosimerism can also be included:

Diastereoisomers are asKed

They wili reading ail this in great cjetarl in 4iir serrr Poc-lll Hovrever <;air l>e covere<j irl vety lrrief

2) Basic considerations Like: Inductive effect, Electromeric effects, Mesomeric,effect' Resonance, writting resonance

structures, Hyperconjugations, reaction types and tntermediates are to be included in any of the units'

lf the students are not aware about them, they will not be able to understand the points covered in syllabus'

They can be taught this when explaining indivrdual concept as rs mentioned in the syllabus

onThu, Apr4,201gat4:55pMMrs,AshaThomasPharmaCy<irsitillirlrrrr;,is(;Dcjyltvlir:dtlrir>wrote:

Fdrwarded message

From: sohan chitIange <sctr:.-lttclllt|;li-lt1c,;Qrr:11i1.{t1.';ll|. r.:,(':r1..>

Date Thu, Apr 4,2019 at 3 39 PM

Subject Fw Fwd, Regardirrg PCI Syllabus 2018 Patterrr Subject POCI

To: Mrs Asha <asira'thrlrrras(ldyl)v() (ldi; 111>

PFA

Thanks & Regards

Dr.Sohan Chitlange

(M) 09922904305

..A diamond is just a piece of coa|, which did we|| under pressure!!! ',

From: Kiran Un,ru .Ur,no cpharn't@sttzamc:ltnpus orq>

Sent:Thu, 04 APr 2019 14:16:56

To: sohanchilange <soharr<;lrililrrgel(@re<lif;ltrail {lor;1>, i;illlaiicfrillar"<lttilt;rttt"rfrti;il r:l::tt

Subject. Fwd: RLgarding PCI Syllabus 2018 Pattern Sublect: POCI

Fri, Apr 5,2019 at 11:14 AM

lnstitute ofSciences & Research

Foruvarded message

To. Ki ra n B hi se <pr ri rr-a cpfia rm {tliaz a ffi cil lll ir l lsj or q>

Resoected Madam

Pls find here the chapter wise suggestion for PCI 201 8 pattern subject: Pharnraceutical Organic chemistry-l

1l

Plmpri, Pune-411 018.

https.//mail googte com/marl/u/0/?ik=9Baebg.1c65&view=pt&search-all&permmsgid=msg-f",,"3A1629951676170864033&dsqt=1&simpl-msg-f%3A1629

Page 8: suggestions communicated to affiliating university (sppu) and ...

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Page 10: suggestions communicated to affiliating university (sppu) and ...

MMU

To

Syllabus correction/ suggestion

!eja! P. Gandh i Pharmacy <[email protected]>To: "Mrs. Asha Thomas Pharmacy,, <[email protected]>

Hello mam

PFA

Tue, Apr 2,2019 at 4:18 PM

&.t1\

Thanks and RegardsSejalGandhi

m iJU"Ous suggestions.docx

Prin{ipdf-Dr. D. Y. Patll Institu

Pharmaceutical, Sciences &Plmpri, Pune-411 019.

hftps://mail.google'com/mail/u/0/?ik=1a0ffd87cc&view=pt&search=all&permmsgid=msg-a%3Ar-31 130g735gg850665,t 9&simnt=mcd_aol^qar_?.r.r ? 1t4

Page 11: suggestions communicated to affiliating university (sppu) and ...

7LDMMflls4Tj0l.lg

Subject: Pharmaceutical analysis - I

Semester - Sem I

Suggestions:

1. Pharmacopoeia, sources of impurities in medicinal agent and limit test should beremoved from syllabus as it is covered in pIC in detail.

2. Preparation and standardizationof compound should be clearly stated.3. Assay of compound should be same in theory and practical. Ex. Assay of ephedrine HCL

and magnesium sulphate is not covered in practicals

4. In unit IV, redox titration permanganometry is not mentioned and that is covered inpracticals. .

5. Very less allotted hours for unit V, electrochemical methods of analysis. In 2015 pattemSPPU syllabus same chapters were allotted total 18hrs. Difficult to complete topic instipulated time.

Subject: Biochemistry

Semester - Sem II

Suggpstions:

1. In unit I, biomolecules details should be mentioned as how much needs to be covered inintroduction of carbohydrate, lipid, nucleic acids, amino acid and protein.

2. Strucfures in pathways should not be mandatory.

3. Disorders related to pathways are mentioned in syllabus which is different as comparedto SPPU 2015 pattem. Questions in university question paper should be pathway withdisorders, as only disorders is part ofpathophysiology.

4. In unit III, amino acid metabolism, syllabus says catabolism of tyrosine and its metabolicdisorders. Alongwith degradation of tyrosine, catabolism of tyrosine also results information of melanin and thyroid hormones. Clarification is required.

[gEJAt P 04^JL

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6t3t2021i1312021 Dr. D.Y. Patil Unitech Society Mail - Final Syllabus FY SY and M Pharm _MQASyllabus FY SY and M Pharm MQA

Final Syllabus FY SY and M Pharm -MQA

1 message

Mrs. Asha Thomas Pharmacy <[email protected]>

To : [email protected]

Respected Sir,

PFA the syllabus of FY SY and M Pharm MQA.

Regards

Dr. Asha Thomas,

Professor and Head-Department of Pharm Chemistry,

Dr D Y Patil Institute of Pharmaceutical Sciences and Research, Pune.

Mon, May 20,2019 at 4:3'l PM

I '1 Final Syllabus BOS-PC.raru 2o8K

Dr. D, Y. ot'ltramaceullcal, & Re*arch

Plmpri. Pune-4l1 018.

a

https://mail.google.com/mail/u/0?ik=98aeb91 cU5gu;sw=pt&search=all&permthid=thread-a%3Ar-8253990961617838251 &simpl=msg-a%3 Ar-3186972

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5114122,12 47 PMDr D Y Patil Unitech Sociely Mail - Revised draft

c01.4|4uUI(ATLO N t-Ro F{ H 0-b T

rs' Asha Thomas Pharmacy <asha'thomas@dypvp'edu'in>

Revised draft lg- 2-Ol72 messaqes

Mrs. Asha Thomas Pharmacy <asha.thomas@dypvp edu'tn>

To: [email protected]

Resoected Sir,

PFA the revised draft of following subjects-,l.Biochemistry(FYSemIl)-|nputsforDrBadheandMrsBabita

2. Medicinal Chemistry -l ( S Y Sem -lV) - lnputs for Dr Lata

3. MpAT( Common .yil.ort for all specializations)-lnputs form Dr Damle and Dr Asha

4'QATPractica|s-|nputsformDrDamIeDrRupaIiandDr.Asha.M Pharm Pharm Chem

-Dr Jadhav will send me'

Regards 'Dr. Asha Thomas,

Professor and Head-Department of Pharm Chemistry,

Dr D Y Patil Institute of Pharmaceutical sciences and Research, Pune.

4 attachments

o11 Medicinalchemistry B Pharm Sem lV'docx

- 25K

.0u11 Pharm Biochem S Y B Pharm Sem ll'doc

-'1 sgK

g1 MPAT.docx

'20K r

,r11 QATII Practicals Sem ll'docx-J 12K

Tue. Aor 30, 2019 at 5:15 PM

sohan chitlange < ail'com> Tue' Apr 30' 2019 at 5:18 PM

To: sawantrl <sawa nt99 <sawant99@ S J hoo co'in>'

svamrutkar2OOO <s co in>' "mrunal'da mle

<[email protected]>' "Chandrakant'Bonde" < nmi

<[email protected]>, toshniwal-ss <toshniwal-ss@ aga gstalele

- gstalele@rediffmail com>

please find ....syllabus for Biochemistry and M.Pharm as an attachment ...please review give inputs as required

Pharmaceutical, Science! & ResearchPimpri, Pune-411 018.

1

4 attachments

g 1 Medici nal-ch e m istry-B-Ph a rm-Se m-lV.docx

'25K

g1 Pharm-Biochem-S-Y-B-Pharm-Sem-ll.doc.-58K

;g"1 MPAT.docx

- 20K' a_-

;1,i"1 QATI|_practicals-Sem-ll.docx' -.-: 12K

7

https://mail.googlecom/mail/u/O/?ik=9Baeb91.UU*u1"*=pt&search=all&r8OO378 1 93639628 1 4 1 9&simpl=msg-a%3Ar80087393

Page 21: suggestions communicated to affiliating university (sppu) and ...

5t14t22. 12 54 PM Dr D Y Patil Unitech Socrcty Mail - M Pharm Pharm chem

Thu, May 2,2019 aI11:22 AM

Since CADD needs to be studied

frp

{

M Pharm Pharm chem1 message

Mrs. Asha Thomas Pharmacy <[email protected]>

To: [email protected]

Respected Sir,

PFA the revised syllabus of M Pharm Pharm Chem.

Changes made are highlighted.

In CADD (MPC 203T), the older of teaching the topics are revised.

sequentiallyRegards and thanksDr. Asha Thomas,

Professor and Head-Department of Pharm Chemistry,

Dr D Y Patil lnstitute of Pharmaceutical Sciences and Research, Pune.

91 Revised M Pharm Syllabus MPC 1st May 2019 SBJ'docx

- 83K

Prir#ipilDr. D. y. patil instit{r6 of

Pharmaceuticat, Scien cJs ir"neJa rcr,Pimpri, pune-+tt

Otg.

1Ihttps://mail.google com/mail/u/O/?ik=98aeb9'1"U56uis\ry=pt&search=all&permthid=thread-a%3Ar1641621097680485265&simpl=msg-a%3Ar55322666

Page 22: suggestions communicated to affiliating university (sppu) and ...

5123122,6:09 PM Dr. D.Y Patil Unitech society Mail - Rules & Syllabus F. y. B. pharmacv 20t9 pattern

B ?HA-LIvl zDW- L{ Lq

Rufes & Syllabus F. Y. B. Pharmacy 2019 Pattern2 messages

Principal Pharmacy <[email protected]> Wed, Jun 19,2019 at 2:58 pMTo: [email protected]

PFA

Dr. S.S.ChitlangePrincipal,

Dr. D.Y.Patil Institute of Pharmaceutical Sciences and Research, pimpri, pune, India(M) 09922904305

o.5 Rules & Syllabus F. Y. B. Pharmacy 2019 pattern.pdf

- 552K

- Principal Pharmacy <[email protected],in>

To: [email protected]. in

[Quoted text hiddenj

*1 Rules & Syllabus F. Y. B. Pharmacy 2019 pattern.pdf

- 552K

Wed, Jun 26,2019 at 12:07 PM

0,P^

Pfinfl'pDr. D. Y. Patil Ins

Pharmaceutical, Scie nceJ& Research

Pimpri, Pune411 018.

.a

https://mail.google com/mail/u/0/?ik=6a81 51 5f98&view=pt&search=all&permthid=thread-a% 3A1243461257 512637397 4&simpl=msg-a%3 Ar42854

Page 23: suggestions communicated to affiliating university (sppu) and ...

principal pharmacy <[email protected]>

B. P t1*RM- 2_Dl<-Lo I qRufes & Syllabus S.y.B.pharma cy 2O1g pattern2 messages

Principal Pharmacy <[email protected]>To: boards@pun. unipune.ac. in

PFA

Dr. S.S.Chitlange

Principal,

Dr. D'Y.Patil Institute of Pharmaceutical Sciences and Research, pimpri pune, India(M) 09922904305

fl T^r19." & Syilabus S.y.B.pharmacy 2018 pattern.pdf

" 491K

v-Principal Pharmacy <[email protected]>To: [email protected]. in

[Quoted text hidden]

f) Tlfg_" & Syilabus S.y.B.pharmacy 2018 pattern.pdf'' 491K

Wed, Jun 19,2019 at 2:59 pM

Wed, Jun 26,2019 at 12:07 pM

Pharmaceutical, SciencUs & Research

Pimpri,.Pune411 018-

https;//mail google com/mail/u/0/?ik=6a81 51 5f98&view=pt&search=all&permthid=thread-a% 3Ar-547 492601g89994563g&simpl=msg-a%3Arg07.1 1t1

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5123122,6:10 PM Dr. D.Y Patil Unitech Society Mail - Rules and Syllabus for M pharm 20.19 pattern

Rules and Syllabus for M. Pharm 2019 Pattern2 messages

Principal Pharmacy <princi'[email protected]>

To: [email protected]

PFA

Dr S.S,Chitlange

Prirrcipal,

Dr. D.Y.Patil Instltute of Pharmaceutical Sciences and Research, Prmpri, Pune, India(M) 0ee22904305

ar1 Rules and Syllabus for M. Pharm 2019 Pattern.pdf

- 1636K

"--' Princi pal Pharmacy <principal. pharmacy@dypvp. edu. in>To: [email protected]. in

louoted lexl hrdderrj

-v1 Rules and Syllabus for M. Pharm 2019 Pattern.pdf

- 1636K

Wed, Jun 19,2019 at 2:59 PM

Wed, Jun 26,2019 at 12:07 PM

A-

Pdincrp4uDr. D. Y. batil in#ty1e of

pr,ailiaclutiLi, sti.nttt & Researdt' "-'

Pimpri' Pune411 010'

https://mail google.com/maillul0l?ik=6a8151 sfg8&view=pl&search=all&permthid=thread-a"/03Ar7989148164542691800&simot=msq-a%3Ar-1289

I

Page 25: suggestions communicated to affiliating university (sppu) and ...

kvvlsel svu,48 u(

BP104T. PHARMACEUTICAL INORGANIC CHEMISTRY (Theory) 45 Hours

Scope: This subject deals with the concepts and monographs of inorganic drugs and

pharmaceuticals.

Objectives : Upon completion of course student shall be able to

o know the sources of impurities and methods to determine the impurities in drugs and

pharmaceuticals

o understand the medicinal and pharmaceutical importance of inorganic compounds

TJIIIT IImpurities in pharmaceutical substances: History of pharmacopoeia, sources

and types of impurities, principle, reaction and procedure involved in the limit

test for chloride, sulphate, iron, arsenic, lead and heavy metals, modified limit test

for chloride and sulihate in general.

Water: Different official waters and official control test for water.

10'hours

General methods of preparation, assay for the compounds superscripted with asterisk (*)

Properties and Medicinal uses of Inorganic Compounds belonging to the following classes

UI\'IT IIAcids, Bases and Buffers: Buffer equations and buffer capacity in general,

buffers in pharmaceutical systems, preparation, stability, buffered isotonic

solutions, measurements of tonicity, calculations and methods of adjusting

isotonicity.

Major extra and intracellular electrolytes: Functions of major physiological

ioris, Electrolytes used in the replacement therapy: Sodium chloride*, Potassium

chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological

acid base balance.

Dental products: Dentifrices, role of fluoride in the.treatment of dental caries,

Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol

cement.

10 hours

TJNIT IIIGastrointestinal agents

Acidifiers: Ammonium chloride* and Dil. HCI

Antacid: Ideal properties of antacids, combinations of antacids, Sodium

Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture

Cathartics : Magnesium sulphate, Sodium orthophosphate,

Protectives and Adsorbents: Kaolin and Bentonite

A,ntimicrobials: Mechanism, classification, Potassium permanganate, Boric acid,

Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations

L0 hours

UNIT IVMiscellaneous Compounds

Expectorants: lotassigm iodide, Ammonium chloride

Emetics: Copper sulphate*', Sodium potassium tartarate

Haematinics: Ferrous sulphate*, Ferrous gluconate

Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite

Astringentsz Zinc Sulphate, Potash Alum

08 hours

atil

UNIT VRadiopharmaceuticals: Radio activity, measurement of radioactivity, properties

}\4

tg3

:Jartl,[a- .o

S"gu1

Page 26: suggestions communicated to affiliating university (sppu) and ...

pes and study of radio isotopes - Sodium

Chromium tt, Erbiuml6e, Gallium6s,

autions & pharmaceutical applications ofradioactive substances.

Note: The weight age of topics while setting SPPU university Question paper should be

proportionate to the teaching hours allotted.

Recommended Books (Latest Editions)

1.. Beckett, A.H. and Stenlake, J. B. 1970, Practical Pharmaceutical Chemistry,Yoll & lI,4th edn, Stahlone Press of University of London.

2. Jeffery, G. H., Bassett, J., Mendham, J. and Cdenney, R., Vogel's Textbook of QuantitativeChemical Analysis,5th edn, Thames Polyechnic, Longman Grgup, uK Ltd, London.3. Gundu Rao, P. 2008, Pharmaceutical and Medicinal Inorganic Chemistry, VallabhPrakashan.

4. Bentley, A.O., Driver, J.E. and Atherden, L.M. 1969, Bentley and Driver's Textbook ofP har m a c e ut i c al C he mi s try, Oxford University Press, London.

6. Anand, S.K. and Chatwal, G.R. 2017, Inorganic Pharmaceutical Chemistry, HimalayaPublishing House Pvt Ltd.7. Block, J.H., Roche, E.B., Soine, T.o and wilson, C.o. 1974, Inorganic Medicinal andP harmaceuti c al C he mis try, Philadelphia, PA.

8. Indian Pharmacopoeia, Ministry of Health and Family Welfare, Controller of PublicationsEdition. New Delhi.

Page 27: suggestions communicated to affiliating university (sppu) and ...

BPI 10P. PHARMACEUTICAL INORGANIC CHEMISTRY (Practical)4 Hours

/ Week

Limit Test of the following:(l) Chloride (2) Sulphate (3) Iron (4) Arsenic (5) Lead (6) Heavy metals

6 turns

Identification test

(l) Magnesium hydroxide (2) Ferrous sulphate (3) Sodium bicarbonate (4)

Calcium gluconate (5) Copper sulphate

3 turns

Test for purity(1) Swelling power of Bentonite .

(2) Neutralizingcapacity of Aluminum hydroxide gel

(3) Determination of Potassium iodate and iodine in Potassium Iodide

3 turns

Preparation of Inorganic Pharmaceuticals(1) Boric acid (2) Potash alum (3) Ferrous sulphate

3 turns

Recommended Books (Latest Editions)

t.

1. Beckett, A.H. and Stenlake, J. B. 1970, Practical Pharmaceutical Chemistry,Yol I & il,4th edn, Stahlone Press of University of London.

2. Jeffery, G. H., Bassett, J., Mendham, J. and Cdenney, R, Vogel's Textbook of Quantitative

Chemical Analysis,5th edn, Thames Polytechnic, Longman Group, UK Ltd, London.

3. Gundu Rao, P. 2008, Pharmaceutical and Medicinal Inorganic Chemistry, Vallabh

Prakashan.

4. Bentley, A.O., Driver, J.E. and Atherden, L.M. 1969, Bentley and Driver's Textbook ofP harmaceutic al Chemistry, Oxford University Press, London.

6. Anand, S.K. and Chatwal, G.R. 2017, Inorganic Pharmaceutical Chemistry,Himalaya

Publishing House Pvt Ltd.

7. Block, J.H., Roche, E.B., Soine, T.O and Wilson, C.O. 1974, Inorganic Medicinal and

Pharmaceutical Chemi stry, Philadelphia, PA.

8. Indian Pharmacopoeia, Ministry of Health and Family Welfare, Controller of Publications

Edition, New Delhi.

NubD;A B'1vawo"Y

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Dr. D. Y.Fal

Pharmaceuticaf , bciences & ResJarch

Pimpri, pune411 01g.

Page 28: suggestions communicated to affiliating university (sppu) and ...

R"pvrsrl Syuu+Btls Fy

BP202T. Pharmaceutical Organic Chemistry - I (Theory) 45 hours

Scope: This subject deals with classification and nomenclature of simple organiccompounds, isomerism, intermediates formed in reactions, important physical properties,reactions and methods of preparation of these compounds. The syllabus also emphasizeson mechanisms and orientation of reactions.

objectives: upon completion of the course the student shall be able too Write the structure, name and the type of isomerism of the organic compoundo Write the reaction, natne the reaction and orientation of reactionso Account for reactivity/stability of compoundso IdentiVconfirm the identification of organic compounds

Course Content:1. General methods of preparation (any 05) and reactibns of class of compounds

superscripted with asterisk (*) to be explained.

2. To emphasize on definition, types, classification, principles/mechanisms,applications, examples and differences.

TINIT 1

Basic principles of organic chemistry:Hybridization of atomic orbitals of carbon, nitrogen and oxygen to formmolecular orbitals. Types of bonds, bond fission, intermolecular forces,inductive effect, steric effect, electromeric, mesomeric effect and resonance.

hyperconjugation, concept of tautomerism.

04 hours

UNIT IIClassification, nomenclature and isomerism

Al Classification of organic compounds1. Compounds containing carbon and hydrogen atoms only : hydrocarbons

(alkanes, alkenes alkynes, aromatic hydrocarbons, polynuclear aromatichydrocarbons, aryl-alkyl hydrocarbons, alicyclic hydrocarbons)

2. Compounds containing carbon, hydrogen and oxygen atoms only(alcohols, phenols, ethers and epoxides, carbonyl compounds, carboxylicacids, esters, anhydrides)

Compounds containing carbon, hydrogen and nitrogen atoms only (amines and imine, nitriles, hydrazines, nitro compounds)

Compounds qontaining carbon, hydrogen, and halogens with oxygen(alkyl halidOs, aryl halides, acyl halides)

5. Compounds containing carbon, hydrogen, oxygen and nitrogen atoms

only (amides, imides, aldoxime and ketoxime)6. compounds containing carbon, hydrogen and sulphur with/without

nitrogen, oxygen and halogen. Sulphonic acids, sulphonylhalides.(At least five mono-functional examples of each class includingaromatic and aliphatic compounds should be covered with their commonnames.) , .,_ -

Bl Common and IUPAC systGhs of nomenclature of organic compoundsIUPAC nomenclature of all classes of compounds: nomenclature of mono-substituted and poly-substituted compounds should be covered.

Cl Structural isomerism in organic compounds, Introduction tostereochemistry, concepts

meso compounds.

of enantiomerism and diastereomerism, I

aJ.

4.

10 hours

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08

Hours

UNIT-IIAlkanes*, Alkenes* and Conjugated dienes*

Halogenation of alkanes, uses of paraffins'

Stabilities of alkengs, it *a E2 reactions - kinetics, order of reactivity

alkyl halides, realrangement of carb

orientation and evidences. El versus

reactions. Chemical Reactions: Ozonol

alkenes, Markownikoff s orientation, free radical addition reactions of alkenes,

Anti Markownikoff s orientation

Stability of conjugated dienes, Diel's-Alder, 1,2 and I,4- electrophilic

addition, free raaicat addition reactions of conjugated dienes, allylic

08

Hours

UNIT-IIIAllryt halides*

SNl and Slr2 reactions - kinetics, order of reactivity of alkyl halides'

,i.rror6.-istry and reaffangement of carbocations. SNl versus Sv2 reactions'

factors affecting SNl and S52 reactions'

Structure and uses of ethylchloride, Chloroform, trichloroethylene,

tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform'

tests, structure and uses of ethyl alcohol,

alcohol, benzyl alcohol, glycerol, and propyleneAlcohols*- Qualitative

chlorobutanol, cetosteryl

glycol.

10 Hours

UNIT.IVldehYdes and ketones)

tromlric effect, Aldol condensation, Crossed Aldol

reaction, Crossed QasfizVaro reaction, Benzoin

condensation, and Perkin condensation'

Qualitative tests, structure and uses of formaldehyde, paraldehyde, acetone'

c]iloral hydrate, hexamine, benzaldehyde, vanillin, and cinnamaldehyde'

0THours

UNIT VCarboxylic acids*

n.iOty "f

carboxylic acids, effect of substituent/s on acidity, qualitative tests

io, .*Uo"yti. u"idr, u-id" and ester. Reactions of interconversion of

carboxylic acidl amides and esters'

Structure and uses of acetic acid, lactic acid, tartaric acidls' citric acid'

succinic acid, oxalic acid, salicylic acid, benzoic acid, benzyl benzoate,

dimethyl phthalate, methyl salicylate and acetyl salicylic acid.

Aliphatic amines* - Basicity, effect of substituent on basicity, qualitative test'

structure and uses of ethanolamine, ethylenediamine

ity Question Paper should

proportionate to the teaching ttours allotted'

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BP208P. Pharmaceutical organic chemistry - I (Practical)

organic chemistry laboratory.

Of,jectives: Upon studying the course, the students shall be able to safely use

serr"eral chemicals, identify them from their physical and chemical properties'

and perform simple laboratory procedures, and prepare a scientific report on the

Scope: This subject deals with physical and chemical properties of organic

comlounds. Thd teaches a student to work judiciously and carefully in an

I. Safety measures in an organic laboratory'

II. Introduction to laboratory techniques: calibration of thermometer,

melting point, boiling point, distillation, and crystallization..

8 turns

III. Systematic qualitative analysis of unknown organic compounds like

l. Preliminary test: color, odour, aliphaticlatomatic compounds, saturation

and unsaturation, etc.

2. Detection of elements like nitrogen, sulphur and halogen by Lassaigne's

test.

Solubility test

Functional group test like phenols, amides, carbohydrates, amines,

carboxylic u"iOr, aldehydes attd ketones, alcohols, esters, aromatic and

halogenated hydrocarbons, nitro compounds and anilides.

Melting point/Boiling point of organic compounds'

Identification of the,tnktto*tt compound from the literature using melting

poinV boiling Point.

rtttini*,r- S-u'nk"o*n organic compounds to be analyzed systematically)

IV. Preparation of suitable solid derivatives from organic compounds

v.Building of molecular models of structures containing various

Recommended Books

1. Furniss, B. S., Hannaford, A. J. Smith, P. W. G.' and Tatchel, A. R', "Vogel's Textbook

of Practical organic Chemistry',, V (ed.), Pearson, L-ondon, 1994

Z. Finar, I. L.,.Or!anic Chemistry Vol. I, V 1"a.;, ELBS, Pearson Education, New Delhi'

2003

3. Eliel, E. L., "stereochemistry of carbon compounds", wiley-Interscience ' 1994

4. Mann, F. G. and Saunders, Ii. C., Practical Organic Chemistry, IV(ed.), Pearson' UK,

2009

.a

Page 31: suggestions communicated to affiliating university (sppu) and ...

Recommended Books

o Morrison, R. T. & Boyd, R. D., Textbook of Organic Chemistry, VI (ed.) ELBS,

London,1996

o Pine, S. H, Organic Chemistry,Y,TataMcGraw Hill, New Delhi, 2007

o Finar, I. L., Organic Chemistry Vol. I, V (ed.), ELBS, Pearson Education, New Delhi,

2003

o Finar, I. L., Organic Chemistry Vol. II, V (ed.), ELBS, Pearson Education, New

Delhi,2003

o Eliel, E. L., "stereochemistry of Carbon Compounds", Wiley-Interscience,1994.

a

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Pimpri, Pune411 018.

@EA

Instittl

Page 32: suggestions communicated to affiliating university (sppu) and ...

BP102T. PHARMACEUTICAL ANALYSIS (Theory) 45 hours

SCOPE : This course deals with the fundamentals of analyical chemistry and principles

of electrochemical analysis of drugs.

oB JE c rIV"'

I {:Hjf5,lif"l'ffi ill1kili.t:l*li*ifi"-'

UNIT-1(a) Pharmaceutical analysis - Definition and scope

l) Different techniques of analysis

2) Methods of expressing concentration

3) Primary and Secondary standards.

(b) Errors : Sources of errors, types of errors, methods of minimizing errors,

accuracy, precision and significant figures

05 hours

UNIT.IIa) Acid base titration: Theories of acid base indicators, classification of acid

base titrations and theory involved in titrations of strong, weak, and very

rveak acids and bases, neutralization curves. Preparation and standardization

of sodium hydroxide, hydrochloric acid, sulphuric acid, Estimation of'ammonium chloride

b) Non aqueous titration : Solvents, acidimetry and alkalimetry titrations, and

estimation of sodium benzoate.

10 hours

UNIT-IIIa) Precipitation titrations: Mohr's method, Volhard's method, Modified

Volhard's method, Fajans method, and estimation of Sodium Chloride I.P.

b) Complexometric titration: Classification, metal ion indicators, masking and

demasking reagents, and estimation of Calcium gluconate I'P'

c) Gravimetry: Principle and steps involved in gravimetric analysis. Purity ofthe precipitate: co-precipitation and post precipitation, and estimation of

Barium sulphate I. P.

12 hours

UNIT-IV t

Redox titrationsa) Concepts of oxidation and reduction

b) Preparation and standardization of Potassium Permanganate I. P., Ceric

Ammonium Sulphate I. P.iB. P. and Sodium Thiosulphate I. P.iB. P.

c) Types of redox titrations (Principles and applications) : Permaganometry,

Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry, Titrations

with Potassium Iodate I. P.

08 Hours

UNIT-V ''- - '

Electrochemical methods of analysis

o Conductometry - Introduction, Conductivi Conductometric titrations,

10 hours

*up

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)boS -V LvnV"( C t S*bp^f

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applications.potentiometry - Electrochemical cell, construction and working of reference

(Standard Hydrogen Electrode, Silver Chloride Electrode and Calomel

Electrode) and Indicator Eectrodes (Metal electrodes and Glass Electrode),

methods to determine end point of potentiometric titration and applications.

Refractometry - Introduction, refractive index, specific and molar refraction,

measurement of RI, Abbe's refractometer and applications.

Polarogaphy - Principle and llkovik Equation.

Note: The weight age of topics while setting SPPU university Question paper should be

proportionate to the teaching hours allotted-

Recommended Books (Latest Editions)

L lndian Pharmacopoeia, Ministry of Health and

Publications Edition, New Delhi'

2. British Pharmacopoeia, British Pharmacopoeia Commission, London' 2015

3. Beckett, A.H. and Stenlake J. B., Practical Pharmaceutical Chemistry, Vol I, Stahlome

Press, University of London.

4. Vogel, A. I., A Textbook of Quantitative Chemical Analysis, Thames Polytechnic,

London, Longman GrouP, UK Ltd'

5. Connors K. A., A Textbook of Pharmaceutical Anal.v'.sis, Third Edition, John Wiley and

. Sons.

6. Christian G.D., Analytical Chemistry, 6/Ed, John Wiley & Sons'

7. Mahadik K.R., Wadodkar S.G., More H.N, Pharmaceutical Analysis, Vol. I and II.

Nirali Prakashan.

8. Kar Ashutosh, Pharmaceutical Drug Analysis, Minerva Press, Nerv Delhi'

9. Day R. A. & Underwood A. L. Quantitative Analysis. slEd., Prentice Hall of India Pvl.Ltd.

New Delhi.

10. skoog, A. D. West, D. M. et al. Fundamentals of Analytical chemistry' 8/ Ed' Thomson

Brookslcole.

11. Willard Merit. Dean Settle, Instrumental Methods of Analysis, 7/Ed, cBS Publisher &

Distributor

12. Sharma, B. K. Instrumental Methods of Chemical Analysis, Goel Publishing House.

Family Welfare, Controller of

Page 34: suggestions communicated to affiliating university (sppu) and ...

BP108P. PHARMACEUTICAL ANALYSIS (Practical)

Preparation and standardization of(1) Aq. Sodium HYdroxide I. P.

(2) Aq. Sulphuric Acid I. P'/ Aq. Hydrochloric Acid I' P'

(3) Aq. Sodium Thiosulfate I. P.

(4) Aq.Potassium Permanganate I. P'

(5) Aq.Ceric Ammonium Sulphate I. P.

4 h/week

3 turns

Assay of the following compounds along with Standardization of Titrant

(l) Ammonium chloride by acid-base titration

(2) Sodium benzoate I. P. by non-aqueous titration

(3) Sodium chloride I. P. by precipitation titration

(4) Calcium gluconate I' P. by complexometry

(5) Hydrogen peroxide I. P./B. P. by Permanganometry

(6) Fenous sulphate I. P. by cerimetry

(7) Copper sulphate I. P. by iodometr

Determination of Normal ity by electro-analytical methods

(l) Conductometric titrations of strong acid against strong base

iZj Conauctometric titration of strong acid and weak acid against strong bul"- _

ififottntiometric titration of strong acid against strong base (Using Sigmoidal

Measurement of refractive index of so

Rectified Spirit, Castor Oil I. P.)

8 turns

3 turns

I turn

Recommended Books (Latest Editions)

L Indian Pharmacopoeia, Ministry of Health and Family Welfare, Controller of

Publications Edition, New Delhi.

British Pharmacopoeia, British Pharmacopoeia commission,. London, 20 I 5

Beckett, R.U. and Stenlake J. B., Practical Pharmaceutical Chemistry Vol 1,1962,

Stahlome Press, University of London'

4. Vogel, A. I., A Textbook of Quantitative chemical Analysis, Thames Polytechnic'

London, Longman GrouP, UK Ltd.

Connors K. 4., A Textbook of Pharmaceutical Analysis. John Wiley and Sons'

Christian G. D., Analyical Chemistry, John Wiley & Sons'

Mahadik K. R., Wadodkar S.G., Moie H. N, Pharmaceutical Analysis Vol' I and II, Nirali

Prakashan.g. Kar Ashutosh, Pharmaceutical Drug Analysis, Minerva Ptess, New Delhi.

2.a

5.

6.

7.

Dr. D. Y.'Patil lAetitute of

Pimpri, Pune-411 018.

Page 35: suggestions communicated to affiliating university (sppu) and ...

EV'SEDSv *ngus v

8P203 T. BIOCHEMISTRY (Theory) 45 hours

Scope: Biochemistry deals with complete understanding of the molecular levels of the chemical

process associated with living cells. The scope of the subject is to provide biochemical facts and

the principles to understand metabolism of nutrient molecules in physiological and pathological

conditions. It is also emphasizing on genetic organization of mammalian genome, hetero &autocatalytic functions of DNA.Objectives: Upon completion of course the students shall able to

I . Understand the catalyic role of enzymes and importance of enzyme in biochemicalprocess.

2. Understand the metabolism of nutrient molecules in physiological and pathological ,.

conditions.

3. Understand the genetic organization of mammalian genome and functions of DNA in the

synthesis of RNAs and proteins.

UNIT -Ia. Biomolecules

o Introduction, classification, chemical nature and biological role ofcarbohydrates, lipids, nucleic acids, amino acids and proteins.

b. Carbohydrate metabolism. Glycolysis - Pathway, energetics and significance.

o Citric acid cycle- Pathway, energetics and significance.

o HMP shunt and its significance; Glucose-6-Phosphate dehydrogenase. (G6PD) deficiency.

o Glycogen metabolism Pathways and glycogen storage diseases (GSD).

o Gluconeogenesis- Pathway and its significance.

o Hormonal resulation of blood slucose level and Diabetes mellitus.

10 hrs

UNIT-1I

^. Biologicaloxidationo Electron transport chain (ETC) and its mechanism.

o Oxidative phosphorylation & its mechanism and substrate level.

o phosphorylation

o Inhibitors ETC and oxidative phosphorylation / uncouplers.

b. Bioenergetics

o Concept gffree energy, endergonic and exergonic reaction,

relationship between free energy, enthalpy and entropy.

. Energy rich compounds; classification; biological significances of ATP

and cyclic AMP.

08 hours

UNIT-III

^. Lipid metabolism

o B-Oxidation of saturated fatty acid (Palmitic acid).

o Formation and utilization of ketone bodies; ketoacidosis.

o De novo synth.ri;,if faty acids (Palmitic acid).

. Biological significance of cholesterol and conversion of cholesterol

into bile acids. steroid hormone and vitamin D.

10 hours

re rsgl

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a)

re-18. iI{{ \Y

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BDS- McY^^txYqar.dt t

Page 36: suggestions communicated to affiliating university (sppu) and ...

. Disorders oflipidmetabolism: hypercholesterolemia, atherosclerosis,

fatty liver and obesity.

b. Amino acid metabolismo General reactions of amino acid metabolism: Transamination,

deamination & decarboxylation, urea cycle and its disorders.

o Catabolism of phenylalanine and tyrosine and their metabolic disorders

(Phenyketonuria, alkaptonuria, tyrosinemia)

. Synthesis and significance of biological substances; 5-HT, melatonin,

dopamine, noradrenaline, adrenaline

o Catabolism of heme; hyperbilirubinemia

UNIT.IV .

Nucleic acid metabolism and genetic information transfero Biosynthesis of purine and pyrimidine nucleotides.

o Catabolism of purine nucleotides and hyperuricemia and gout disease.

o Organization of mammalian genome.

o Structure of DNA and RNA and their functions.

o DNA replication (semi conservative model)

o Transcription or RNA synthesis.

o Genetic code. Translation or Protein synthesis and inhibitors.

10 hours

UNIT-VEnzyr.nes

o lntroduction, properties, nomenclature and IUB classification ofenzymes.

o Enzyme kinetics (Michaelis plot, Line Weaver Burke plot).

o Enzyme inhibitors with examples.

o Regulation of enzymes: enzyme induction and repression, allosteric

enzyme-regulation.

o Therapeutic and diagnostic applications of enzymes and isoenzymes.

. Coenzymes-Structureandbiochemical functions; Co-factors.

07 hours

Note: The weight age of topics while setting SPPU university Question paper should be

proportionate to the teaching hours allotted.

Recommended Books (Latest Editions)

l. David Nelson and Cox M. M., Lehninger's Principles of Biochemistry, 4/Ed., Palgrave

Macmillon.

2. Robert K. Murry, Daryl K., Granner and Victor W. Rodwell, Harper's Biochemistry,2T/Ed,

McGraw Hill.3. Lubert Stryer, W.H., Freeman & Company, Biochemistry, New York

4. U. Satyanarayana & U. Chakrapani, Biochemistry,3/8d., Books & Allied (P) Ltd.

5. Rao, A. V. S. S. Rama Rao, Textbook of Biochemistry, first edition, UBS Publishers'

Distributors Pvt. Ltd. ''- -.6. Deb, A. C. Viva & Practical Biochemistry,3lBd,New Central Book Agency (P) Ltd.

7. Conn Eric. E. and Stumpf, Paul K. et al., Outlines of Biochemistry, Wiley student edition.

8. Gupta R. C. and Bhargavan, S. Practical Biochemistry, 5/Ed, CBS publishers and distributors.

Page 37: suggestions communicated to affiliating university (sppu) and ...

9. David T. Plummer, Introduction of Practical Biochemistry. 3lEd, Tata McGraw-HillEducation P\rt. Ltd.

10. Rajagopal and Ramakrishna, Practical Biochemistry for Medical students, Orient BlackSwan(1e83)

11. Harold Varley, Varley's Practical Clinical Biochemistry, 6lEd., CBS Publishers, NewDelhi.

12.David T. Plummer, Introduction to Practical Biochemistry, III (ed.), McGraw-Hill PublishingCo., New York, 1987.

13. Alan H. Gowenlock, Varley's Practical Clinical Biochemistry, VI (ed.), Butterworth-

Heinemann Ltd., UK & CBS Publication, New Delhi, 2002.

Pharmaceutical, Sciences & Researdt

Pimpri, Pune.411 018.

Page 38: suggestions communicated to affiliating university (sppu) and ...

BP 209 P. BIOCHEMISTRY (Practical) 4hlweek

1. Qualitative analysis of carbohydrates (Glucose, Fructose, Lactose, Maltose,

Sucrose and Starch)3 turn

2. Iden fication tests for amino acids (any one aromatic and one aliphatic) I turn

3. Iden fication tests for proteins (albumin and casein) I turn4. Qualitative analysis of urine for abnormal constituents ( at least four

abnormal constituents)2 turn

5. Determination of blood creatinine 1 turn

6. Determ nat on of blood sugar by Folin-Wu method/Glucose-oxidase method I turn

7. Determ nat on of serum total cholesterol. I turn

8. Preparation of buffer solution and measurement of pH (any two). I turn

9. Quantitative analysis of reducing sugars (DNSA method) and Proteins

(Biuret method).I turn

10. Determination of salivary amylase activity. I turn

I 1. Study the effect of temperature on salivary amylase activity, I turn

12. Study the effect of substrate concentration on salivary amylase activity. 1 turn

Recommended Books (Latest Editions)l. David Nelson and Cox M. M., Lehninger's Principles of Biochemistry, 4/Ed., Palgrave

Macmillon.

2. Robert K. Murry, Daryl K., Granner and Victor W. Rodwell, Harper's Biochemistry,2TlEd,

McGraw Hill.3. Lubert Stryer, W.H., Freeman & Company, Biochemistry, New York

4. U. Satyanarayana & U. Chakrapani, Biochemistry,3lEd., Books & Allied (P) Ltd.

5. Rao, A. V. S. S. Rama Rao, Textbook of Biochemistry, first edition, UBS Publishers'

Distributors Pvt. Ltd.

6. Deb, A. C. Viva & Practical Biochemistry,3lEd., New Central Book Agency (P) Ltd.

7. Rajagopal and Ramakrishna, Practical Biochemistry for Medical students, Orient BlackSwan

(1e83)

8. Harold Varley, V'arley's Practical Clinical Biochemistry,6lEd., CBS Publishers, New

Delhi.

9. David T. Plummer, Introduction to Practical Biochemistry, III (ed.), McGraw-Hill Publishing

Co., New York, 1987.

10. Alan H. Gowenlock, Varley's Practical Clinical Biochemistry, VI (ed.), Butterworth-

Heinemann Ltd., UK & CBS Publication, New Delhi, 2002.

Page 39: suggestions communicated to affiliating university (sppu) and ...

tVPseD SV Cop V

BP30lT. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Theory) 45 Hours

Scope: This subject deals with general methods of preparation and reactions of some organic

compounds. Reactivity of organic compounds is also studied here. The syllabus emphasizes on

mechanisms & orientation of reactions. Chemistry of fats and oils are also included in the syllabus.

Objectives: Upon completion of the course the student shall be able to

l. write the structure. name and the type of isornerisrrr of the organic compound

2. write the reaction. name the reaction and orientation of reactions

3. account for reactivity/stabitity of compounds

4. prepare small organic compounds

Note:General methods of preparation and reactions of compounds superscripted with asterisk (,*) to be

explairred .

UNIT-IBenzene and its derivativesA. Introduction to benzene, orbital picture, resonance in benzene, Huckel's rule

B. Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedel-

Craft' s alky I ation- reactivity, I im itation s, Friede | -Craft' s acyl ation.

C. Substituents, efl'ect of substituents on reactivity and orientation of mono substituted

benzene compounds towards electrophilic substitution reaction

UNIT-IIPhenols* - Acidity of phenols, ef'fect of substituents on acidity, qualitative tests for

phenols, structure and uses of phenol, cresols, resorcinol. naphthols

Aroiratic Amines* - Basicity of amines, effbct of substituents on basicity, Nitrosation

reaction, coupling and Sandmayer's reaction, Hinsberg Test, synthetic uses of aryl

diazonium salts.

UNIT-IIIStereo Isomerism:

a. Optical isomerism

i. Elements of symnretry'. chiral and achiral molecules

ii. Optical activity. enantiomerism. d iastereoisomerism, meso compounds

iii. D & L system of nomenclature of optical isomers, sequence rules, R & S system

of nomenclature of optical isomers

b. Geometrical isomerism

i. Nomenclature of geometrical isomers ((,'is & Truns, E & Z, Syn &.4i?/i systems)

ii. Metlrocls of Seterrnination of confisuration of seometrical isomers.

UNIT-IVPolyn uclear hyd roca rbons:

Synthesis, reactions and structure and medicinal

anthracene, d i phen y I methane, triphen ylmethane and

UNIT-VCycloalkanes*

Stabilities - Baeyer's strain thboilr: limitation of Baeyer's

Moffltt's modiflcation. Sachse Mohr's theorv (Theory ofcyclopropane and cyclobutane only.

uses of naphthalene, phenanthrene,

their derivatives.

strain theory. CoLrlson and

strainless rines)- reactions of

l0 Hours

l0 Hours

l0 Hours

05 H<lurs

Page 40: suggestions communicated to affiliating university (sppu) and ...

UNIT-VIFats and Oils - Hydrolysis, Hydrogenation, Saponiflcation and Rancidity of oils.

02

Hou rs

Note: The weight age of topics while setting SPPU university Question paper should be

proportionate to the teaching hours allotted.

Recommended Books

L Morrison, R. T. & Boyd, R. D., Textbook of Organic Chemistry, VI (ed,) ELBS, London,

1996

2. Pine, S. H, Organic Chemistry, V, Tata McGraw Hill, New Delhi, 2003

3. Finar, I. L., Organic Chemistry Vot. [, V (ed.), ELBS, Pearson Education, New Delhi, 2003

4. Joule and Mills, Heterocyclic Chemistry, IV (ed.), Blackwel Publishing House, Oxford, UK,

5. 2004

6. Li, J. J., Name Reactions, III (ed.), Springer, Berlin, 2006

7. Stereochemistry of Organic Compound Principles and Applications by' Nasipuri. Revised

Edition. New Age International Publishers.

8. Stereochemistrl, 6or'1-ormation and Mechanism by P.S. Kalsi, 718d2008, New Age International

Publishers, Neiv Delhi.

9. Furniss, B. S., Hannaford, A. J. Smith, P. W. G., and Tatchel, A. R., "Vogel's Textbook ofPractical Organic Chemistry", V (ed,), Pearson, London, 1994

10. Finar, L L., Organic Chemistry Vol. I, V (ed.), ELBS, Pearson Education, New Delhi, 2003

11. Mann, F. C. and Saunders, B. C., Practical Organic Chemistry, IV(ed.), Pearson, UK,2009

Page 41: suggestions communicated to affiliating university (sppu) and ...

BP301P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical) 4 Hrs/week

I Experiments involvingL Recrystallisation

2. Steam distillation

laboratory techniques

I turns

II Experiments involving Separation of Binary mixtures 2 turns

III Determination of saponification value of oil samples (Any two) I turns

IV Synthesis of following compounds

I. Benzanilide /phenyl benzoate /acetanilide from aniline/ phenol/ aniline by

benzoy lation/acy lation reaction

2. 2, 4, 6-Tribromoaniline/para-bromo acetanilide from aniline

3. p-bromo Acetanilide by halogenation (Bromination) reaction.

4. 5-Nitrosalicylic /meta-dinitrobenzene fiom salicylic acid/'nitrobenzene by

nitration reaction

5. Benzoic acid/ Salicylic acid from alkyl benzoatelalkyl salicylate by

hydrolysis reaction.

6. l-Phenylazo-2-naphthol from aniline by diazotization and coupling

reactions/ p-lodobenzoic acid fiom P-aminobenzoic acid by replacement

reaction.

7. Benzil from benzoin by oxidation reaction

8. Dibenzal acetone fiom benzaldehvde bv Claisen-Schmidt reaction

I 1 turns

Dr. D. Y. Patil Institu'fe of

Pharmaceutical, Sciences & Research

Pimpri, Pune-411 018.

Page 42: suggestions communicated to affiliating university (sppu) and ...

?npv

BP40lT. PHARMACEUTICAL ORGANIC CHEMISTRY -III (Theory)45

Hours

Scope: The subject imparls knowledge on stereo chemical aspects of organic compounds and

organic reactions, imporlant name reactions, chemistry of important heterocyclic compounds. It

also emphasizes on rnedicinal and other uses of organic compounds.

Objectives: At the end of the course. the student shall be able to,

l. understand the methods of preparation and properties of'organic compounds

2. explain the stereochenrical aspects of organic compounds and stereo clrernical reactions

3. know the medicinal uses and other applications of organic compounds

-tUNIT-IStereo isomerism

i. Reactions of Chiral molecules

ii. Racemic modiflcation and resolution of racemic mixture.

iii. Introduction to Asvmmetric synthesis with suitable exam

UNIT-IIGeometrical isomerism

i. Confbrmational isomerism in n-Butane, decalin, and cyclohexane.

ii. Stereoisomerism in biphenyl compounds (Atropisomerism) and conditions fbr optical

activity.

iii. Stereosoecif-rc and stereoselective reactions

UNIT-IIIHeterocyclic com pou nds

a.Nomenclature and classiflcation of heterocyclic compounds in to classes: Oxvgen

cohtaining flve & six membered rings, Nitrogen containing flve & six membered

rings, sulphur containing five & six member rings; Oxygen & nitrogen containing five

& six membered rings, oxygen & sulphur containing flve & six membered rings, and

sulphur and nitrogen containing five & six membered r;ings; benzo-fused heterocyclic

compounds as benzimidazole, benzthiazole, benzopyran, and their derivatives ofmedicinal imporlance ( Arr1,one fl'om each class),

b. Chemistry (reactivity, stability, acidiQ and basicity), Synthesis ( any one),

reactions and medicinal uses of following compounds

le. Furan. and Thioohene

UNIT-IVChemistry(reactivity, stabilify, acidity and basicity), Synthesis ( any two), reactions

and medicinal uses of following compoundsiderivatives

a. Pyrazole, Irnidazole. Oxazole and Thiazole.

b. Pyridine. Pvrirnidine. Purine. Quinoline, lsoquinoline. Acridine. Azepines.

lndole and their derivatives ( any one fiom each class)

- ]

IUNIT-VName Reactions of synthetic importance

Pinacol-Pinacolone, Hofmann, Baeyer-Villiger oxidation , Benzilic acid rearrangement

reaction, Beckmann's rearrangement and Schmidt rearrangement, Claisen-Schmidt

condensation. Clemmensen reduction, Wolff rearrangement. Oppenauer-oxidation and

Daki n reaction. and B irch'reduction.

07

Hou rs

06

Hours

08

Hou rs

t2Hou rs

t2

Hou rs

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Recommended Books

l. Morrison, R. T. & Boyd, R. D., Textbook of Organic Chemistry, VI (ed.) ELBS, London,

1996

2. Advanced General Organic Chemistry-A Modern Approach by Sachin KumarChosh,3/Ed.

2009, New Central Book Agency (P) Ltd.

3. Pine, S. H, Organic Chemistry, V, Tata McGraw Hill, New Delhi, 2003

4. Finar, I. L., Organic Chemistry Vol. I, V (ed.), ELBS, Pearson Education, New Delhi, 2003

5. Joule and Mills, Heterocyclic Chemistry, IV (ed.), Blackwell Publishing House, Oxford,

uK, 2004

6. Li. J. J., Name Reactions. lll (ed.), Springer, Berlin, 2006

7. Stereochemistry of Organic Compound Principles and Applications by Nasipuri, Revised

Edition, New Age International Publishers.

8. Stereochemistry Confonnation and Mechanism by P.S. Kalsi, 7lEd2008, New Age lnternational

Publishers, New Delhi. '9. Stereochemistry of Organic Compound Principles and Applications by Nasipuri, Revised

Edition, New Age International Publishers.

F'--(o' 7-a^l>'d D{ AB Thulrwcu\

6i-=l(ol

as

sld

le

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co ^lM

El\l b4T$0ilJ

MODERN PHARMACEUTICS(MPH 103T)

Unit No Topics deleted Topics added02 Validation and calibration master

plan, Government regulationsand manufacfuring process

model

02 validation of specific dosage

formProcess validation of any one

dosago form02 Validation of cone blender,

mixer granulator and tabletcompression machine

02 Technology transfer from R & Dto pilot plant to plant scale

05 Linearity Concept ofsignificance, Standard deviation ,

Chi square test, students T-test,ANOVA test

'05 Study of consolidationparameters and Heckel Plotshifted to Unit 4

05 Disolution models includingHiguchi, Peppas plot, zerc order,first order and Hixson Crowell.

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tauN,tM tt$l\ATlolus

PHARMACEUTICS PRACTICALS - II(MPH 20sP)

Experiment

No(As per

previous

syllabus

Modification/Remark

Formulation and evaluation ofspherule s/mi croparticle s

Microparticles can bethe option for spherule

9, 70,11, 15,

16,17, lgCase studies for the following:

r Bioavailability studies ofParacetamol in animals.

. Pharmacokinetic andryIVC data analysis

r In vitro cell studies forpermeability and

metabolismr Computer Simulations in

Pharmacokinetics andPharmacodynamics

. ComputationalModelingof Drug Disposition .

. Developing ClinicalDataCollection manual

. Sensitivity Analysis, andPopulation Modeling

The experiments are

modified as case

studies

Design of Experiment for anyformulation using DesignExpert'Software

Only formulation DOEis expected

Formulation data analysis UsingDesign Expert@ Software ( Nochange)

Dataanalysis andinterpretation oftheprevious experiment is

T0 incoryorate herbal andchemical actives to developproducts to address Dry skin,acne, blemish, Wrinkles,bleeding gums and dandruff

Experiment2l, and22are merged

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A'?|,L4

td Ft

From: Sanjeevani Deshkar ([email protected])

To: [email protected]; pdchaudhari-21 @yahoo.co.in

Date: Sunday, April21,2019,02:42 PM GMT+5:30

Respected sir,

I am forwarding you the minutes of meeting of BOS held on 8th April.

lam also forwardino vou draft of revised M.Pharm Svllabus (modern Pharmaceutics, andPractical for term ll)'for your kind perusal. I have highlighted ihe changes in yellow. Please shareyour opinion.

lhave mailed Dr. Shilpa chaudhari mam, the examination reforms (Bloom's taxonomy)suggested

byA|CTE and adopted by our institute.

In case of any corrections in the syllabus, please share your opinion.

Thanks and Regards,

Dr. Sanjeevani Deshkar

Asso. Professor

D epartment of Pharmaceutics

Dr. D.Y Patil Institute of Pharmaceutical Sciences & Research,

Pimpri, Pune

Minutes of Meeting BOS Pharmaceutics.docx

17.9k8

MODERN PHARMACEUTICS revised syllabus.docx

1 7.1 kB

PHARMACEUTICS PRACTICALS Sem ll revised syllabus.docx

15.2kB

Dr D .,iglh'[:l+ra'mffi

i;F#HJY[?,.J,"nPfmpri, pune+tid'tb*.a

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R.eVrsFL SI/LAR

MODERN PHARMACEUTICS(MPH 103T)

Scope

Course designed to impart advanced knowledge and skills required to learnvarious aspects and concepts at pharmaceutical industries

Objectives

Upon completion of the course, student shall be able to understando The elements ofpreformulation studies.o The Active Pharmaceutical Ingredients and Generic drug Product

development

. Industrial Management and GMp considdrations.

. optimization Techniques & pilot plant Scale Up Techniques

. Stability Testing, steilization process & packaging of dosageforms.

THEORY 60 HRS

1. a. Preformation Concepts - Drug Excipient interactions - different methods,kinetics of stability, Stability testing. Theories of dispersion and pharmaceuticalDispersion (Emulsion and Suspension, SMEDDS| preparation and stability.Latge and small volume parental -physiological and formulation consideration,Manufacturing and evaluation. 12 Hrs

b. Optimization techniques in Pharmaceutical Formulation: Concept andparameters of optimization, Optimization techniques in pharmaceuticalformulation and processing. Statistical design, Response surface method,Contour designs, Factorial designs and application in formulation . l0 Hrs

3 cGMP & Industrial Management: Objectives and policies of current goodmanufacturing practices, layout of buildings, services, equipments and theirmaintenance Prbductitn' management: Production orgini)ation, materialsmanagement, handling and transportation, inventory management and control,production and planning control, Sales forecasting, budget and cost control,industrial and personal relationship. Concept of Total Quality Management.

Hrs

10 Hrs

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4 Compression and compaction: Physics of tablet compression, compression,

consolidati_gn,__-effect of friction, distribution of forces, compaction profiles,

s o&W-iA 1o Hrs

5 Diffusion parameters, Dissolution parameters and Pharmacokinetic

parameters, , Similarity factors - fZ and fL, Disol.^

Higuchi, Peppas plot, zero order, first order and Hixson

06 HrsREFERENCES

1. Theory and Practice of Industrial Pharmacy By Lachmann and Libermann2.Pharmaceutical dosage forms: Tablets Vol. 1-3 by Leon Lachmann

3. Pharmaceutical Dosage forms: Disperse systems, Yol,l-2; By LeonLachmann.

4.Pharmaceutical Dosage forms: Parenteral medications Vol. l-2;By LeonLachmann.

5. Modern Pharmaceutics; By Gillbert and S. Banker.

6. Remington's Pharmaceutical Sciences.

7. Advances in Pharmaceutical Sciences Vol. l-5; By H.S. Bean & A.H.Beckett.

8. Physical Pharmacy; By Alfred martin

9. Qentley's Textbook of Pharmaceutics - by Rawlins.

10. Good manufacturing practices for Pharmaceuticals: A plan for total quality

control, Second edition; By Sidney H. Willig.11. Quality Assurance Guide; By Organizationof Pharmaceutical producers ofIndia.

l2.Drug formulation manual; By D.P.S. Kohli and D.H.Shah. Eastern

publishers, New Delhi.

13. How to practice GMPs; By P.P.Shanna. Vandhana Publications, Agra.14. Pharmaceutical Process Validation; By Fra. R. Berry and Robert A. Nash.

15. Pharmaceutical Preformulations; By J.J. Wells.

16. Applied production and operations management; By Evans, Anderson,

Sweeney and Williams.17 . Encyclopaedia of Pharmaceutical technology, Vol I - m.

(bq. E ,_s ,luua,D.a_

Dr. D. Y. PatilPharmaoeutical, Sciences & Researc

Plmpri, Pune411 018.

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1.

2..tJ.

4.

5.

6.

(svlsltrb V ul€ o<

PHARMACEUTICS PRACTICALS . II(MPH 20sP)

To study the effect of temperature change, non solvent addition,incompatible polymer addition in microcapsules preparation

Preparation and evaluation of Alginate beads

Formulation and evaluation of gelatin /albumin microspheresFormulation and evaluation of liposomes/niosomes

Formulation and evaluation of g,lgS

Improvement of dissolution characteristics of slightly soluble drug bySolid dispersion technique.

7. Comparison of dissolution of two different marketed products /brands8. Protein binding studies of a highly protein bound d-g & poorly protein

bound d-g9, ease studies for th llowing:

a. Bioavailability studies of paracetamol in animals.

b. Pharmacokinetic and IVIVC data analysis

c. In vitro cell studies for permeability and metabolism' d. Computer Simulations in Pharmacokinetics and

Pharmacodynamics

e. Computational Modeling of Drug Disposition

f. Developing Clinic alData Collection manual

g. Sensitivity Analysis, and population ModelinglO.Deiffiiif;S;p€'iimeneimr

4ll,..,on using Design Experr@

Software

l l.Formulation data anarysis using Design Expert@ Software1 2.Quality-by-Design in Pharmaceutical Development

l3.Developmbnt and evaluation of Creams

l4.Development and evaluation of Shampoo and Toothpaste base

;deve ipsitpr$4utts

tireedin6lefii$.,pn4itrarditf ff

Dut"xg)Dr. D. Y. Patil tnstitute of

"harmaceutical, Sciences & ResearchFimpri, Pune-411 018.

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RvcoH\4w>+1:-oNs

IVII}IUT'ES OIq AD-I.XOC D(OIiRJD OF ST{J

rxELD ON 23/01 12fi1g AT n230 F"F/I, [N Tx{tr t\CADE'l\4nC EJA]I,L'

S lr\ryTR[B Ax P]i{UI,E' P{J}]tr UN_[ j.RS [TY, PU }{8, - /t -I

1 CI s7

the follov'ring mernberi vrere present for the said meeting:

Dr. P.D- Chaudhari - Chairman

Dr- S- S' C hitlange

Dr- Anagha Joshi

Dr" Atul Pathak

Dr. Atmaram Pawar

Dr- Suvarnalngale

The following items were discussed in the meeting'

Item No.l: To decide staff requiremenu positions for conduct of Pharm' D' course'

Based on departrment wise workload and faculty oadre ratio of AICTE and pcl for conduct of

pharrn. D course, it was uranimously decide'd that staffrequirement ftlr conduct of pharm' D

coruse shall be 1:2:7(Total 10)'

Fourth FifrhTotal

WorkloadSr. No. Departnoent First Second Third

t4 0 0 3420 0

1

Pharmaceutical

ChemistrY

Phqrmaeeutics 6 7 8 7 0 28

2 J 0 28

PharmacologY7 ll 7

aJ

l0 7 27 1l f,f,

4 Pharmacv Practice 0

0 0 0 70 7

11 152lrasvvlts- -/

33 35 36 37Total

Year

(t-'Ao

STAFF REQTJIREMENT

Number of students

YQtp'

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3

Fractice or Pharrrr. D

l3 Pharmaceutical Dosage

FomsM.Phann in Pharmaceutics or IndustrialPirarmacy or Phann. D

11. Fharmacotherapeutics -1,II and III

M.Fharm Pharmacy pracitce olPharrnacology ci' Pham. D

15. Community Pharmacy M.Phanrr in Phannacy practice orPharmacology or Pharmaceutics or phann. D

t6. Hospital Fharmacy M.Pharm in Fharmacy practice orPharmacology or Pharmaceutics or pharm. D

t7. Clinical Pharmacy M.Pharm in Pharmacy practice or pharm. D18. Computer Science or

Compuier Application inpharrnacy _

MCA

19. ivlathematics

ltem No.3: Clarification on Fharmacology-I practical for Second Year Pharm. D. as per

circuXarissuedbyFCl(Ref no: l4-D6n0l6-pci/32181-34447 Dated 2310S12016).

Phanrracy Council of India (PCD had issued a policy circular (Ref no: 14-12612016-

pctl32l8l-34447 Dated 23/08/2016) regarding Clarification on Pharin. D. Regulations, 200g

relating to Pharmacology-I praiticd which states as follows-

c6[t was noted that practicals related to PHdRMACOLOGY-I are placed at Page No. 57 instead

. of Page No. 44. Since Page No. 44 has already been given to'25 COMMUMTY PHARMACY

CIHEORI)', Page No. 57 be read as Page No. 43 A

Thus it was u^nnimously decided to accept this change and to conduct practical for

Pharmacology- I subject. Accordingly, changes were done in tables of course of studv and

examinations as follows on page no 5 and 8: -

Second Year:

S.Il{O Name of Subject lVo. ofhours ofTheory

No. ofhours ofPractical

hlo. ofhonrs ofTutorid

(1) a) (3) (4) (s)

2.1 Pathophysiology 3 I

2.2 Pharmaceufi cal Microbio logy JaJ I

2.3 Pharmacognosy & Phytopharrnaceuticals aJ

aJ I

2.4 Phamracology-I 3 J I

2.5 Community Pha4Eacy 2 I

2.6 Pharmacotherapeutics-I aJ J I

Total tr{ours t7 12 6 :35

)E.

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.stLrciyof-',aricusmethcdsforcollectionoiblocc,bodyfluidsanciurinefrcn

Experimental animals'

. compu,rer simulaiions oi" iollowing expeiments through cornputerized simuiated

Software programme using softvgare su-ch as Ex-Pharm' X-cology etc'

a.TorecordConcentra.rionResponseCurves(CRC)ofAcetylcholineusingsuitable

isolated tissue PreParations

b.Studyofthemiotica4dmydriaticeffectofrirugsusingrabbiteyes.

l0.TorecordConcentrationResponseCurves(CRC)ofAcetylcholineusingsuitable

' Isolated tissue PreParations

ii. To record concentration Response curves (cRc) of Histamine using suitable Isolate<i

tissue PreParatlons

To Study of analgesic activity of drugs using Eddy's hot plate analgesiometer/ tail flick

anaigesiometer in mice

13. To Study of locomotor activity of drug using actophotometer in mice

14. To Study of muscle relaxant properry of drug using rotarod in mice'

15. Study of agonistic and antagonistic effects of drugs gsing Guinea -pig ileum preparation'

16. To study the effects of drugs on intestinal motility using frog's esophagus model

17. Tostudy the effects of drugs using rat uterus preparation.

18. To 'study the anticonvulsant property of drugs (any one model)'

1g. To study antihistaminic property of drug using histamine induced anaphylactic reaction in

guinea Pigs.

20. To study the dpomorphine-induced compulsive behaviour (stereotypy) in mice'

2l.TosfudytheantiinflanmatorypropertyofindomethacinagainstcalTageenan-induced

paw oedema

22.Tostudytheanxiolyticeffectofdiazepaminmiceusingmirrored-chamberapparatus.

23. To demonstrate the effect of various diugs on the blood pressue and respiration of

anaesthetized dog'

24. T ostudy the effect of anthelmintics on earthworms'

25- To study the taming effect of chlorpromazine'

26. To study the effects of drugs on vas deferense of the male rat'

27 -Tostudy the effect of5!rugs onpesticide toxicity using rats as model'

28. To study the effect of drugs otin"uuy metal toxicity'

Note: conduct nrinimum 15 practicals to ensure the exPected outcome'

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12. Tostudy the rouies cf administraticn of drugs iil animals (Rats' Mice' R'abbits)'

13. study of theory, principle, procedure involved aird inie-rpretaiion of given resulis for the

following exPeri menis:

Analgesic property of drug using analgesiometer'

Antiinflammatory effect of drugs using rat-pa'w edema method-

Anticon ulsant activity of drugs using ma,ximal electroshock and pen*'ylene tetrazole

methods.

17. Antidepressant activity of drugs using pole climbing apparatus and pentobarbitone

induced sleePing time methods'

1g. Locomotor activity evaluation of <irugs using actophotometer and rotorod

19. Cardiotonic activity of drugs using isolated frog heart and mammalian heart preparations'

20. To study the anxiolyic effect of diazepam in mice using mirrored-chamber apparatus'

21. To Study effect of different drugs on isolated frog's heart'

22. ToStudy of analgesic activity of drugs using Eddy's hot plate analgesiometer / tail flick

analgesiorneter in mice

23. iostudy the effects of drugs on intestinal motility using frog's esophagus model'

24. Todemonstrate the effect of various drugs on the blood pressure and respiration of

anaesthetized dog'

Note: conduct minimum 15 practicals to ensure the expected outcome"

Scheme tical Examination:Sessionals Annual

02 10

04 10

08 30Maj or ExPeriment (BtoassaY';

04 10Minor Experiment (lnterpreauon or

giveri Graph or simulated experiment)/

Viva

Max Marks

I)uration

02 t0

20 70

3hns 4hrs

for regularity,

Accordingly, changes are done in syllabus on page no 43' 43-A and 52'

14.

15.

16.

ctical sessional Plus 10 marks

' promptrl€ss,liva-voce and record maintenance)'

730

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Ilrena t\do.5:To l-ulci-u,rct lPharr,n. D- (Fos'c Baccaiaurea'ce) ;orogramr.

'ihe course structure adapted by u.niversity for conduct of Fharm. D course mentions only

pharm. D course, though the regulations ior Pharrcr. D and Phann- D- (Post Baccalaureate)

are ayeady included in it. Hence, ii was decided to re.rise the iitle page and to induct Phann-

D. (post Baccalaureate) (lateral entry oi B. Pharm graduates to Fourth Year Pharm. D)

program in course structue adapted by university'

IFACULTV OF PHARMACEUTTCAT SCIENCES}

{JruEVHRSETV #F PUHH

COUR.SE STRIICTUR,E & SYttAE[

DOCTOR. OF' PHAR.MACY IPHAR M.D] COUR.SE

&

D O CTOR. OF' PF{ARMACY -F OST BACCALA{IR.EATE

.. {Hq4'niv[.D -PE] C0URSE

@,FFECTI\.E FR'OM acapnnnrc YEAR 2819-2020)

78)

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33

It vias aiso ciecided to include combined syllabus foL Pharrnacotherapeutics I ct, II in cou-rse

structure as follor'.rs on page no 78-A, 18-B and 78-C.

4"7 PX-XArR-ivtrACOTI-iERAi.Dtr{JTnCS n & nI (T'FXtrORY)

Theorry: 3 X{ns. /Ween<

1. Scope and Objectives: This course is designed to impart knowledge and sltills necessary

for coniribution to quality use of medicines. Chapters dealt cover briefly pathophysiology and

mostly therapeutics of various diseases. This will enable the studeni to understand the

pathophysiology of common diseases and their management-

At completion of this course it is expected that students will be able to understand:

a. The pathophysiology of selected disease states and the rationale for drug therapy.

b. The therapeutic approach tc managernent cf these diseases.

c. The controversies in drug therapy.

d. The importance of preparation of individualized therapeutic plans based on diagnosis.

e. Needs to identiff the patient-specific parameters relevant in initiating drug therapy, and

f. monitoring therapy (including alternatives, time-course of clinical and laboratory

indices of therapeutig response and adverse effects).

g. Describe the pathophysiology of selected disease states and explain the rationale for

drug therapy.

h. Summarize the therapeutic approach tb management of these diseases including

reference to the latest available evidence.

i. Discuss the controversies in drug therapy.

j. Discuss the preparation of individualized therapeutic plans based on diagnosis.

k. Identiff the patient-specific parameters relevant in initiating drug tlerapy, and

monitoring therapy (including altematives, tine-course of clinical and laboratory

indices oftherapeutic response and adverse effects).

2. Course materials

TEXT BOOKSa. Clinical Pharmacy and Therapeutics -Walker and Whittlese4 Churchill Livingstone

publication. i

b. Pharmacotherapy: A Pathophysiologic approach - Joseph T- Dipiro et al. Appleton &Lange.

REF'ERENCE BOOKS

a. Pathologic basis of disease - Robins SL, W.B.Saunders publication.

b- Pathology and therapeutics for Pharmacists: A Basis for Clinical Pharmacy Practice -

Green and Harris, Chapman and Hall publication.

c. Clinical Pharmacy and Therapeutics - Eric T. Herfrndal, Williams and Wilkins

Publication.

.d. Applied Therapeutics: The clinical Use of Drugs. Lloyd Young and Koda-I(mble MA.

e. Avery's Drug Treatment, 4th Edn, 1997, Adis Intemational Limited.

f. Relevant review;articles from recent medical and pharmaceutical literature.

)92-

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zi " 7 r flA.,Rir;dA C O T IT E P"A\P E nj'lf ri C S ri & [iL (]P P*A CT ll C An')

iPnaerilean : 3 IJirs"AVee[<

Fnac'cleans :

ments ciesigned to comPiemeni

n; attending ward rounds; follow uP

Ilotted patients; case presentation

record of cases Presented and the

submittedattheendofthecourseforevaluation.Aminimumof20p."t"*.a and recorded covering most common diseases'

the leciures by

the progress and

upon discharge.

same should be

cases should be

10 marks for regularitY,

Assignments : nts on the topics given to them' Topics

drug theraPY of various diseases' A

000 words] should be submitted for

evaluation-

Format of the assignment:

t'

;3. on at the end of the academic year'

4. It shall be comPuter draft coPY'

5. Name and signature of the student'

6. ' Time allocaGd for presentation may be 8+2 Min'

Schenne of Practical Examination:

Sessionals Annual

a 05 l5

l0 25Maior Experiment

Minor ExPerimenl 03 15

Viva 02 15

70

04hrsMax Marks z0

Duration O3hrs

Note:Totalsessionalmarksis30(20forpracticalsessionalpiuspromptJless, viva-voce and record maintenance)'

ltern I{o.8: To add Declanation of class in course structure at the end of I' II' III' fV and

VyearofFharm.Dandattheendofthefinalyearexarnilration.

The course structure adapted by university for conduct of Pharm' D course mentioned only

hrst class and distinction class of passing in "Minimum marks for passing examination"

Henceitwasdecidedtotdd-the-Declarationofclassincoursestructureaitheendofl'II'III'

IV and V year of Pharm. D and at the end of the final year examination as follows on page no

10:

%3

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iq-4

Theory and pr'actic al of aparticular subject shall be considereci as individual subjects ior the

purpose of pass criteria- Those candidates who fail in one or n-rore subjects shall ha-ve to

appearonly in the subject so failed, in the subsequent examinations.

l"LgS* C Vurs Y rrLq {)

P ltV,l*^'D l\t..j'Lrec

Dr. D. Y.

?harmaeutical, Sciences & ResearchPimpri, Fune-411 018.

tl

w{

j