Subtrees Comparison of Phyloge netic Trees with Applications to Two Component Systems Seque nce Classifications in Bacteri al Genome Yaw-Ling Lin 1 Ming-Tat Ko 2 1 Dept Computer Sci. & Info. Management, Providence University, Taichung, Taiwan. 2 Institute of Information Science Academia Sinica, Taipei, Taiwan
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Subtrees Comparison of Phylogenetic Trees with Applications to Two Component Systems Sequence Classifications in Bacterial Genome Yaw-Ling Lin 1 Ming-Tat.
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Subtrees Comparison of Phylogenetic Trees with Applications to Two Component Systems Sequence Classifications in Bacteri
2 Institute of Information ScienceAcademia Sinica, Taipei, Taiwan
Yaw-Ling Lin, Providence, Taiwan 2
Motivation – Where the problems
come from?
Yaw-Ling Lin, Providence, Taiwan 3
Two-Component System
• Two-component systems (2CS):– Sensor histidine kinase– response regulator
• The major controlling machinery in order for bacteria to encounter a diverse and often hostile environment
Yaw-Ling Lin, Providence, Taiwan 4
2CS in Pseudomonas aeruginosa PAO1
http://www.pseudomonas.com/
“Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.” Nature. 2000 Aug 31;406(6799):947-8. by Stover CK, Pham XQ, Erwin AL, et al.