static-content.springer.com10.1007... · Web viewSupporting Information Synthesis and photophysical studies on naphthalimide derived fluorophores as markers in drug delivery Nidhi

Supporting Information

Synthesis and photophysical studies on naphthalimide derived fluorophores as markers in drug delivery

Nidhi Singh, Ritika Srivastava, Anuradha Singh and Ramendra K. Singh*Bioorganic Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad – 211002, India*Corresponding author (Tel.: +91.532.2461005; E mail address: [email protected]

Fluorescent studies on synthesized fluorophores compounds 2-6:

2 3 4

5 6

6-(6-Acetylamino-1, 3-dioxo-1H, 3H-benzo [de]isoquinolin-2-yl)-hexanoic acid (2)

6-(6-Ethoxycarbonylamino-1,3-dioxo-1H,3H-benzo[de] isoquinolin-2-yl)-hexanoic acid (3)

6-(6-tert-Butoxycarbonylamino-1,3-dioxo-1H,3H-benzo[de] isoquinolin-2-yl)-hexanoic acid (4)

6-(6-Methanesulphonylamino-1, 3-dioxo-1H, 3H-benzo [de]isoquinolin-2-yl)-hexanoic acid (5)

6-[1, 3-Dioxo-6-(toluene-4-sulfonylamino)-1H, 3H-benzo [de]isoquinolin-2-yl]-hexanoic acid (6)

Solvatochromic studies on compound 2-6

Fig.1. Solvatochromism of compound 2 (absorption and emission spectra)

Fig.2. Solvatochromism of compound 3 (absorption and emission spectra)

Fig.3. Solvatochromism of compound 4 (absorption and emission spectra)

Fig.4.

Solvatochromism of compound 5 (absorption and emission spectra)

Fig.5. Solvatochromism of compound 6 (absorption and emission spectra)

Time-resolved fluorescent measurement studies on compound 2-6

Fig.6.

Fluorescence Lifetime of compound 2 Fig.7.

Fluorescence Lifetime of compound 3

Fig.8. Fluorescence Lifetime of compound 4 Fig.9. Fluorescence Lifetime of compound 5

Fig.10. Fluorescence Lifetime of compound 6