Supporting Information Synthesis, insecticidal sctivities and structure- activity relationship study of dual chiral sulfilimines Sha Zhou*, Xiangde Meng, Ruyi Jin ‡ , Yi Ma, Yongtao Xie, Yu Zhao, Lixia Xiong, Zhengming Li* National Pesticidal Engineering Centre (Tianjin), State Key Laboratory of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), College of Chemistry, Nankai University, Tianjin 300071, China ‡ Shenzhen Neptunus Bioengineering Co.,LTD, Shenzhen, China 518057 Table of Contents General procedure for compound 2·············································S1 General procedure for compound 4·············································S1 General procedure for compound 5·············································S1 General procedure for compound Ia-k··········································S2 General procedure for compound IIa-k·········································S2 CoMFA analysis by SYBYL······················································S3 HMRS·········································································S4
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static-content.springer.com10.1007... · Web view(20 mmol) and triethylamine (20 mmol) in dichloromethane (50 ml) was slowly added to a solution of anhydride 1a-d(20 mmol) in dichloromethane
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Supporting Information
Synthesis, insecticidal sctivities and structure-activity relationship
study of dual chiral sulfiliminesSha Zhou*, Xiangde Meng, Ruyi Jin‡, Yi Ma, Yongtao Xie, Yu Zhao, Lixia Xiong, Zhengming Li*
National Pesticidal Engineering Centre (Tianjin), State Key Laboratory of Elemento-Organic Chemistry,
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin),
College of Chemistry, Nankai University, Tianjin 300071, China
‡Shenzhen Neptunus Bioengineering Co.,LTD, Shenzhen, China 518057
Table of Contents
General procedure for compound 2·································································································S1General procedure for compound 4·································································································S1General procedure for compound 5·································································································S1General procedure for compound Ia-k·····························································································S2General procedure for compound IIa-k····························································································S2CoMFA analysis by SYBYL·········································································································S3HMRS··································································································································S4
The general procedure for compound 2
Synthesis of 1-(methylthio)propan-2-amine 2, pale yellow liquid, yield 57.8%, 1H NMR (400 MHz,