“State of the Art Treatment” in Deformity Adolescent Idiopathic Scoliosis Mr Evan Davies University Hospital Southampton.

“State of the Art Treatment” in Deformity

Adolescent Idiopathic Scoliosis

Mr Evan DaviesUniversity Hospital Southampton

Robert Jackson 1971-1995

• 1975 British Scoliosis Group

• Harrington Rod

• Spinal Cord Monitoring

• Boston Brace

Nick Boeree 1958-2012

• Appointed 1995

Screw Design

AIS

• Little High level evidence

• RCTs challenging to perform

• Low numbers of intervention

Genetics

Druk mutant Zebrafish

• Mst1rb overexpressed in pineal gland

Associations • Anterior spinal

overgrowth

• Relative shorter spinal cord length

• Tall Stature

• Low BMI

• Low bone mass

Aetiology Summary

• No single cause

• Multifactorial

• Primary genetic cause but related to fully erect posture

Treatment

Bracing

EBSJ V2(2) 2011

Blood

Excellence in Spine