Armaturenfabrik · Apparatebau · Steriltechnik Valves and fittings for food and pharmaceutical industries GmbH + Co. KG 201 mpilation Stainless steel components for pharmaceutical industry and high purity applications Tubes,fittings,couplings,valves, vessels and heat exchangers NEUMO-Ehrenberg-Group 2 Co
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Stainless steel components for pharmaceuticalindustry … · BioConnect® blind part form V for BioConnect® screwed version Page 13 ... 76,1 76,1 2 112 105 ... Dimensions für DIN
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Armaturenfabrik · Apparatebau · Steriltechnik
Valves and fittings for food and pharmaceutical industries
GmbH + Co.KG
201
mpilation
Stainless steel components
for pharmaceutical industry
and high purity applications
Tubes,fittings,couplings,valves,
vessels and heat exchangers
NEUMO-Ehrenberg-Group
2Co
Armaturenfabrik · Apparatebau · Ster i l technik
Valves and fittings for food and pharmaceutical industries
NEUMO GmbH + Co.KG
2 01/10
Within 50 years this early start led to the well-known NEUMO-Group ,which is currently represented with its production facilities
and trading companies in four continents with 1400 employees.
Looking for the nearest contact? Please visit our group's members under "LINKS".
Nowadays NEUMO is producing and supplying tubes,fittings and valves,vessels and heat exchangersmade from stainless steel as well as highly corrosion resistant alloys (like e.g. Hastelloy materials) for the
pharmaceutical, biotechnological, chemical and food processing industries.
NEUMO Germany has specialized in construction,development and production of components for aseptic technology and high purity systems.
The product range contains special tubes, couplings, all types of fittings and accessories,vessels etc. as well as special constructions.
NEUMO is offering sophisticated and well-engineered solutions for Your individual question and demand together in combination with quality products of highest reputation.
Our highly experienced,skilled and motivated team is committed to Your success.
Thinking "STAINLESS" at NEUMO means experience, expertise and the right program.
That's why you should go for NEUMO products.We are here for You.
Get in contact with us!
Who is NEUMO
Content
NEUMO GmbH + Co. KG Page 2Content Page 2BioConnect® Screwed Version Page 3BioConnect® Threaded connection end for screwing Page 4BioConnect® Liner for screwing Page 5BioConnect® Flanged Version Page 6BioConnect® Flange form R Page 7BioConnect® Flange form V Page 8BioConnect® Clamp Version Page 9BioConnect® Clamp formule form R Page 10BioConnect® Clamp formule form V Page 11BioConnect® Blind Parts Page 12BioConnect® blind part form V for BioConnect® screwed version Page 13BioConnect® blind part form V for BioConnect® flanged version Page 14BioConnect® blind part form V for BioConnect® clamp version Page 15BioConnect® Non return Valve Page 16BioConnect® Sampling Valve Page 17BioControl® Articles I Page 18BioControl® Articles II Page 19BioControl® Blind Flange Page 20BioControl® Block Flange Page 21BioControl® Inline Housing Page 22-23BioControl® Angle Housing Page 24-25BioControl® Sight Glass Set Page 26BioControl® Partner Products (Example) Page 27Connect S® Flanged Version Page 28Connect S® Clamp version Page 29NEUMO-Pharmatube - High purity tube and fittings Page 30NEUMO-Fittings DIN 11865 Page 31
NEUMO was founded in 1947 in order to produce valves and fittingsfrom stainless steel for food technology.
DN d s H M6 8 1 36 M 16 x 1,58 10 1 36 M 18 x 1,510 13 1,5 37 M 22 x 1,515 19 1,5 37 M 30 x 1,520 23 1,5 39 M 36 x 225 29 1,5 44 M 42 x 232 35 1,5 45 M 52 x 240 41 1,5 46 M 56 x 250 53 1,5 47 M 68 x 265 70 2 64 M 90 x 380 85 2 64 M 100 x 3100 104 2 66 M 130 x 4
DN d s H M
13,5 13,5 1,6 37 M 22 x 1,517,2 17,2 1,6 37 M 26 x 1,521,3 21,3 1,6 37 M 30 x 1,526,9 26,9 1,6 39 M 36 x 1,533,7 33,7 2 44 M 42 x 242,4 42,4 2 45 M 52 x 248,3 48,3 2 46 M 56 x 260,3 60,3 2 47 M 68 x 276,1 76,1 2 64 M 90 x 388,9 88,9 2,3 64 M 100 x 3
114,3 114,3 2,3 66 M 130 x 4
Dimensions for DIN 11866 line A, DIN 11850
DN d s H M
1/2’’ 12,7 1,65 37 M 22 x 1,53/4’’ 19,05 1,65 37 M 30 x 1,51’’ 25,4 1,65 39 M 36 x 2
1 1/2’’ 38,1 1,65 45 M 52 x 22’’ 50,8 1,65 47 M 68 x 2
2 1/2’’ 63,5 1,65 64 M 90 x 33’’ 76,2 1,65 64 M 90 x 34’’ 101,6 2,11 66 M 130 x 4
NEUMO keeps one of Europe's biggest stock for High Purity Stainless Steel Tube and Fittings.
Whatever dimensional standard is required in pharmaceutical industries - NEUMO has got it!
NEUMO Pharmatube High Purity Stainless Steel Tube is produced according technical specifications as follows:
welded acc. DIN 11866/ISO 1127/DIN 17457, PK2Tolerances: D4/T4mat.grade: 1.4435/BN2 (316L)orseamless acc. DIN 11866/ISO 1127/DIN 17458, PK2Tolerances: D4/T4mat.grade: 1.4435/BN2 (316L)
internal surface roughness: Ra < 0,8µmoptional Ra < 0,6µmoptional Ra < 0,4µm and better
In addition NEUMO offers to the US-orientated pharmaceutical industries original High Purity tubingfulfilling all specification details of ASME-BPE including fittings and clamp ferrules.
AVAILABLE DIMENSIONS
DN ISO 1127 DIN 11866/11850 ASME-BPE
4 6,0 x 1,0 6,35 x 0,896 8,0 x 1,08 13,5 x 1,6 10,0 x 1,0 9,53 x 0,89
10 17,2 x 1,6 13,0 x 1,515 21,3 x 1,6 19,0 x 1,5 12,7 x 1,6520 26,9 x 1,6 23,0 x 1,5 19,05 x 1,6525 33,7 x 2,0 29,0 x 1,5 25,4 x 1,6532 42,4 x 2,0 35,0 x 1,540 48,3 x 2,0 41,0 x 1,5 38,1 x 1,6550 60,3 x 2,0 53,0 x 1,5 50,8 x 1,6565 76,1 x 2,0/2,3 70,0 x 2,0 63,5 x 1,6580 88,9 x 2,3 85,0 x 2,0 76,2 x 1,65
100 114,3 x 2,3/2,6 104,0 x 2,0 101,6 x 2,11
310 /
NEUMO-FITTINGS DIN 11865
Fittings made of stainless steel for aseptic, chemical and pharmaceutical techniques:
The DIN standard 11865, which was issued beginning of 2003 defines the design of fittings (T-pieces, bends, reducing parts for welding) made of stainless steel for the aseptic, chemical and pharmaceutical areas:
The DIN standard committee for mountings 4.1 has developed the DIN 11865 with its explicit specifications, based on previous experiences from applications, practical usage and works standards. These are in particular:
• basic dimensions with tolerance indications• hygienic classes• surface consistency of the inner and outer surfaces acc. to the applied hygienic class• tolerances of the wall thickness and sphericity• permissible wall thickness reduction within the area of forming• materials and their qualities / purity (e.g. ferrite content)• labeling• product description and order designations• inspections and documentation• packaging and transport
With this new DIN standard a further building block is made available for both, the planner and user of the plant, to achieve an optimal design of a piping for the aseptic area.
For the objective of applying a continuous aseptic concept for the construction of the plant, further issues and standards besides the DIN 11865 have to be taken into consideration:
• DIN 11866 "Pipes made of stainless steel for the aseptic, chemical and pharmaceutical area"• optimal connection technology, e.g. NEUMO BioConnect, ConnectS or DIN 11864• best possible selection of the valve technology: e.g. diaphragm valve, aseptic globe valves• e.g. connection system NEUMO BioControl for applications such as pressure
or temperature measurement techniques• As far as technically feasible: Application of orbital welding technology
...and of course: Sufficient experience of the planner, the future operator and the supplier!
We will gladly provide advise on the complex task: STERILE TECHNOLOGY.Approach our specialized staff. Call for us!
T-pieces, form T (long)
T-pieces , form TK (short)
T-pieces , form TR (long, reduced)
T-pieces , form TKR (short, reduced)
Elbow 90°, form BL.-90
Elbow 45°, form BL.-45
Reducer concentric , form RK
Reducer eccentric , form RE
1 10
NEUMO Pharmatube
Sta in less s tee ltub ing for
pharmaceut ica l andBiotech industr ies -
Specia l A l loys 1.4435
DIN 11866
ASME-BPE
TP 316L
1.4404
2.4602/ AlloyC22
1.4539/904L
AL6-XN
Sta in less s tee ltub ing for
pharmaceut ica l andBiotech industr ies -
Specia l A l loys
NEUMO GmbH + Co.KGArmaturenfabrik · Apparatebau · Ster i l technik
Bioprocessing equipment
Table of contents
Table of contents page 2
NEUMO Pharmatube ECO , mater ia l grade 1.4404 page 3
NEUMO Pharmatube S , mater ia l grade 1.4435 page 3
NEUMO Pharmatube XS , mater ia l grade 1.4435 page 4
NEUMO Pharmatube BPE , mater ia l grade TP 316L page 4
NEUMO Pharmal loy , mater ia l grade 1.4539 page 5
NEUMO Al loy C22 , mater ia l grade 2.4602 / A l loy C22 page 5
NEUMO f i t t ings,coupl ings and addi t iona l tub ing qual i t ies page 6
NEUMO brochures page 7
2
NEUMO is offering from stock the following tube qualities and executions:
Stainless steel tubes for pharmaceutical,biotechnological and other high purity applications have always been one of NEUMO’s core businesses.Today NEUMO holds one of Europe’s biggest and most comprehensive stocks for highpurity tubing in her home town Knittlingen in South Germany.Other members of NEUMO-Group in UnitedStates,Switzerland and Israel contribute with additional substantial stocks in pharma tubes of all dimensional and material grades used in high purity industries. Our highest quality is based on long term contracts with Europe’s and America’s best tube mills.NEUMO is relying on only a few specialized ,accredited and certified mills to produce our special pharma brands NEUMO PharmatubeECO , NEUMO Pharmatube S, NEUMO Pharmatube XS and Neumo Pharmalloy .This guarantees highest qualitylevels for our tubes.Since many years our engineers have been supporting European and American standardization committees for bioprocessing equipment like DIN and ASME.BPE.They have substantially influenced the development of standardslike DIN 11866,DIN 11865 and others as well as the comprehensive American standard ASME-BPE 2002 .Based on this experience and know-how we are offering to our customers all necessary support and advise forissue or revision of their companies’ own piping classes and standards.
On request we are offering training and seminars regarding international standardization of stainless steel tubing and other bioprocessing equipment in Your company (or ours).Please ask us for a proposal!
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3
NEUMO Pharmatube ECO
NEUMO Pharmatube S
(DIN 11850,ser. 2) (ISO 1127)
DN AD x WD DN AD x WDdimension (mm) dimension (mm)
15 19,0 x 1,5 15 21,3 x 1,620 26,9 x 1,6
25 29,0 x 1,5 25 33,7 x 2,032 42,4 x 2,0
40 41,0 x 1,5 40 48,3 x 2,050 53,0 x 1,5 50 60,3 x 2,065 70,0 x 2,0 65 76,1 x 2,080 85,0 x 2,0 80 88,9 x 2,3
100 104,0 x 2,0 100 114,3 x 2,3125 129,0 x 2,0 125 139,7 x 2,6150 154,0 x 2,0 150 168,3 x 2,6200 204,0 x 2,0
DIN 11866, part A DIN 11866, part B
Available dimensions:
Seamless and welded stainless steel tubes , mat. grade 1.4404/316L acc. DIN 11866,Hygienic class H2 with optimized tolerances for orbital welding
Internal surface : Ra. Max. 0,8µm / 1,6µm in longitudinal weld area (radial measurement!) Outside surface: pickled or bright annealed ; on request outside polished Additional requirement: AD 2000 W2 (important for European Pressure Directive PED!)
As an option: Electropolishing of internal surface for improoved roughness profile, improoved cleanability,prevention of particle sediments and other substantial advantages according Hygienic Class HE2
(DIN 11850,ser. 2) (ISO 1127) (ASME-BPE)
DN AD x WD DN AD x WD OD AD x WDdimension (mm) dimension (mm) dimension (mm)
4 6,0 x 1,0 4 1/4" 6,35 x 0,896 8,0 x 1,0 68 10,0 x 1,0 8 13,5 x 1,6 3/8" 9,53 x 0,89
10 13,0 x 1,5 10 17,2 x 1,6 1/2" 12,7 x 1,6515 19,0 x 1,5 15 21,3 x 1,6 3/4" 19,05 x 1,6520 23,0 x 1,5 20 26,9 x 1,625 29,0 x 1,5 25 33,7 x 2,0 1" 25,4 x 1,6532 35,0 x 1,5 32 42,4 x 2,040 41,0 x 1,5 40 48,3 x 2,0 1 1/2" 38,1 x 1,6550 53,0 x 1,5 50 60,3 x 2,0 2" 50,8 x 1,6565 70,0 x 2,0 65 76,1 x 2,0 2 1/2" 63,5 x 1,6580 85,0 x 2,0 80 88,9 x 2,3 3" 76,2 x 1,65
100 104,0 x 2,0 100 114,3 x 2,3 4" 101,6 x 2,11125 129,0 x 2,0 125 139,7 x 2,6150 154,0 x 2,0 150 168,3 x 2,6 6" 152,4x2,77200 204,0 x 2,0 200 219,1 x 2,6
DIN 11866, part A DIN 11866, part B DIN 11866, part C
Available dimensions:
Seamless and welded stainless steel tubes , mat. grade 1.4435/316L acc. DIN 11866,Hygienic class H3 with optimized tolerances for orbital welding
Internal surface: Ra. Max. 0,8µm including weld areaOutside surface: polished or bright annealedDelta-Ferrit-content: max. 0,5% (dimensions DN 125 – DN 200 max. 3,0%)Additional requirement: AD 2000 W2 (important for European Pressure Directive PED!)
As an option: Electropolishing of internal surface for improoved roughness profile, improoved cleanability,prevention of particle sediments and other substantial advantages according Hygienic Class HE3
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4
NEUMO Pharmatube BPE
OD AD x WDdimension (mm)
1/4" 6,35 x 0,893/8" 9,53 x 0,891/2" 12,7 x 1,653/4" 19,05 x 1,65
1" 25,4 x 1,651 1/2" 38,1 x 1,65
2" 50,8 x 1,652 1/2" 63,5 x 1,65
3" 76,2 x 1,654" 101,6 x 2,116" 152,4 x 2,77
(ASME-BPE)
Available dimensions:Seamless and welded stainless steel tubes , mat. grade 316L acc.ASME-BPE, Hygienic class ASME-BPE SFT1 with optimized tolerances for orbital welding
Internal surface: Ra. max. 0,5µm / average 0,38µm Outside surface: polished or bright annealedAdditional requirement: ASTM A 249/269/270/S2
As an option: Electropolishing of internal surface forimprooved roughness profile,improoved cleanability, prevention ofparticle sediments and other substantial advantages accordingSurface Class ASME-BPE SFT4 or ASME-BPE SFT5
ASME-BPE is a standard for„BioProcessing Equipment“ (=BPE) like tubing, fittings,valvesetc. that was originally developed in the United States by equipment manufacturers and engineers from thepharmaceutical industry.
NEUMO and her sister companies VNE (USA) and EGMO (Israel)have contributed to the development of this standard with theircontinous and ongoing work in the American and European com-mittees of ASME-BPE.
NEUMO Pharmatube XS
(DIN 11850,ser. 2) (ISO 1127) (ASME-BPE)
DN AD x WD DN AD x WD OD AD x WDdimension (mm) dimension (mm) dimension (mm)
4 6,0 x 1,0 4 1/4" 6,35 x 0,896 8,0 x 1,0 68 10,0 x 1,0 8 13,5 x 1,6 3/8" 9,53 x 0,89
10 13,0 x 1,5 10 17,2 x 1,6 1/2" 12,7 x 1,6515 19,0 x 1,5 15 21,3 x 1,6 3/4" 19,05 x 1,6520 23,0 x 1,5 20 26,9 x 1,625 29,0 x 1,5 25 33,7 x 2,0 1" 25,4 x 1,6532 35,0 x 1,5 32 42,4 x 2,040 41,0 x 1,5 40 48,3 x 2,0 1 1/2" 38,1 x 1,6550 53,0 x 1,5 50 60,3 x 2,0 2" 50,8 x 1,6565 70,0 x 2,0 65 76,1 x 2,0 2 1/2" 63,5 x 1,6580 85,0 x 2,0 80 88,9 x 2,3 3" 76,2 x 1,65
100 104,0 x 2,0 100 114,3 x 2,3 4" 101,6 x 2,11
DIN 11866, part A DIN 11866, part B DIN 11866, part C
Available dimensions:
Seamless and welded stainless steel tubes , mat. grade 1.4435/316L acc. DIN 11866,Hygienic class H4 with optimized tolerances for orbital welding
Internal surface: Ra. max. 0,4µm including weld area Outside surface: polished or bright annealedDelta-Ferrit-content: max. 0,5%Additional requirement: AD 2000 W2 (important for European Pressure Directive PED!)
As an option: Electropolishing of internal surface for improoved roughness profile, improoved cleanability,prevention of particle sediments and other substantial advantages according Hygienic Class HE4
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NEUMO Pharmalloy for highly corrosive liquids
NEUMO Alloy C22 für highest corrosive liquids
DN AD x WDdimension (mm)
8 13,5 x 1,610 17,2 x 1,615 21,3 x 1,620 26,9 x 1,625 33,7 x 2,032 42,4 x 2,040 48,3 x 2,050 60,3 x 2,065 76,1 x 2,380 88,9 x 2,3
100 114,3 x 2,6
ISO 1127
Dimensions acc. ISO 1127Seamless and welded stainless steel tubes, mat. grade1.4539/904L acc. DIN 11866, Hygienic class H3 with optimized tolerances for orbital welding
Internal surface: Ra. Max. 0,8µm including weld areaOutside surface: polished or bright annealedDelta-Ferrit-content: max. 0,5%
Additional requirement: AD 2000 W2 (important for European Pressure Directive PED!)
As an option: Electropolishing of internal surface forimprooved roughness profile,improoved cleanability, prevention of particle sediments and other substantial advantages accordingHygienic Class HE3
DN AD x WDdimension (mm)
1/4" SCH10 13,75 x 1,653/8" SCH10 17,15 x 1,651/2" SCH10 21,34 x 2,113/4" SCH10 26,67 x 2,11
1" SCH10 33,4 x 2,771 1/4" SCH10 42,16 x 2,771 1/2" SCH10 48,26 x 2,77
2" SCH10 60,32 x 2,772 1/2" SCH10 73,02 x 3,05
3" SCH10 88,9 x 3,054" SCH10 114,3 x 3,05
Dimensions acc. ANSI B36.19
Available dimensions:Seamless and welded Nickel Alloy tubes ;mat. grade 2.4602/Alloy C22
Internal surface: mechanical polished with Ra. Approx.. 0,8µm, especially in the weld area roughness could partially exceed due to technical reasons. As a result of hardnessof the material and technical difficultiesof the polishing process we do partially supply these tubes with shortened lengths of 2000 mm only. This effects especially the smaller dimensions.
Outside surface: pickled or bright annealed;on request outside polished!
As an option: Electropolishing of internal surface for improoved roughness profile, improovedcleanability,prevention of particle sedimentsand other substantial advantages
Neumo Alloy C22-pipes are also available without inside polish from our stock in Germany and the United States!
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NEUMO is also supplying:
6
For all above mentioned tube dimensions and material grades NEUMO is offering fittings for automatic machine welding like bends,tees and
reducers from own production as well as flanged,screwed or clamped couplings for high purity applications as f.e.NEUMO BioConnect,
TC-ferrules and DIN 11864. Not to forget our unique , worldwide patented high purity coupling NEUMO ConnectS that works without any
elastomere sealing as well as our special sight glass BioControl, BioCheck sampling valves and other additional equipment.
Please ask for our literature!
FITTINGS FOR PHARMACEUTICAL INDUSTRIES
NEUMO is part of the worldwide acting NEUMO-Group which includes manufacturing facilities and stainless steel warehouses all over
Europe and the United States.This allows us to offer from our group’s stocks nearly all known dimensions and grades for stainless steel tubes
according all international standards.
Please ask us also for
- Dairy tube acc. DIN 11850 in material grades 1.4301 / 304 and 1.4404 / 316L
- Dairy tube acc. SMS 3008 in material grades 1.4301 / 304 and 1.4404 / 316L
- Dairy tube acc. ASTM A 270 in material grades 304L and 316L
- Welded and seamless tubes acc. ISO 1127 in material grades 1.4301, 1.4541,1.4571,1.4404 and 1.4435
- Welded and seamless tubes acc. ASTM A 312 in material grades 304L und 316L
- Tubes in special alloys 1.4539 , 1.4462 , Alloy C22 , C276 and AL6-XN
Other stainless steel tubes from NEUMO
- according European Pressure Directive PED 97
- according ASME Pressure Vessel Code
- according Chinese and Russian Pressure Vessel Regulations
STAINLESS STEEL VESSELS AND TUBE SYSTEMS FOR ASEPTIC PROCESSES
Valves and fittings for food and pharmaceutical industries
NEUMO GmbH + Co.KG
2
Fittings made of stainless steel for aseptic, chemical and pharmaceutical techniques:
The DIN standard 11865, which was issued beginning of 2003 defines the design of fittings (T-pieces, bends, reducing parts for welding) made of stainless steel for the aseptic, chemical and pharmaceutical areas:
The DIN standard committee for mountings 4.1 has developed the DIN 11865 with its explicit specifications, based on previous experiences from applications, practical usage and works standards. These are in particular:
• basic dimensions with tolerance indications• hygienic classes• surface consistency of the inner and outer surfaces acc. to the applied hygienic class• tolerances of the wall thickness and sphericity• permissible wall thickness reduction within the area of forming• materials and their qualities / purity (e.g. ferrite content)• labeling• product description and order designations• inspections and documentation• packaging and transport
With this new DIN standard a further building block is made available for both, the planner and user of the plant, to achieve an optimal design of a piping for the aseptic area.
For the objective of applying a continuous aseptic concept for the construction of the plant, further issues and standards besides the DIN 11865 have to be taken into consideration:
• DIN 11866 "Pipes made of stainless steel for the aseptic, chemical and pharmaceutical area"• optimal connection technology, e.g. NEUMO BioConnect, Connect S or DIN 11864• best possible selection of the valve technology: e.g. diaphragm valve, aseptic globe valves• e.g. connection system NEUMO BioControl for applications such as pressure
or temperature measurement techniques• As far as technically feasible: Application of orbital welding technology
...and of course: Sufficient experience of the planner, the future operator and the supplier!
We will gladly provide advise on the complex task: STERILE TECHNOLOGY.