Speakers - Jordan University of Science and Technology · Dr. Mahmoud Alfaqih ... 1:50-2:05 Advances in the treatment of metastatic lung cancer Dr. Osama Alshari ... Postdoctoral

9th Scientific Conference

“JUST to Adjust Your Health: Time

to Give Back to the Community”Organized by:

Faculty of Medicine – Jordan University of Science & Technology

In Partnership with:

This Conference is organized in collaboration with:

Sponsors

مستودع أدوية الكندي

مستودع أدوية الصباغ

مستودع أدوية أبو شريف

Chair

Dr. Wail Hayajneh

Treasurer

Prof. Firas Alzoubi

Scientific Committee:

Dr. Abdallah Alzoubi (Chair)

Dr. Ashraf Oweis

Dr. Mahmoud Alfaqih

Dr. Adi Khassawneh

Dr. Jehan Hamadneh

Dr. Liqa Rousan

Dr. Samir Al-Bashir

Dr. Rami Alazab

Financial Committee

Dr. Rashid Ibdah (Chair)

Dr. Rami Jahmani

Dr. Ahmad Al Omari

Dr. Rami Saadeh

Social Committee

Dr. Laila Ababneh (Chair)

Dr. Tagleb Mazahreh

Dr. Mohammad Alqudah

Student: Ammar Saadeh

Student: Lamis Al-Hallaq

Communication Committee

Dr. Ahmad Altarifi (Chair)

Student: Ahmad Alqaoud

Student: Majd Shalakhti

Conference Secretary

Ms. Khitam Abu Shosheh

Media Coordinator

Mr. Muhannad Malkawi

Committees

A Message from the Chair of the Conference

Dear Colleagues;

It is our great pleasure at the Faculty of Medicine, Jordan University of Science andTechnology (JUST), to welcome you all as you attend the 9th Scientific Conference of theFaculty of Medicine. We are most honored to organize this conference in partnership withKing Abdullah University Hospital (KAUH) and Princess Haya Biotechnology Center (PHBC), aswe all synchronize in serving our students, staff, community, and beloved Jordan. I feel mosthonored and privileged to take on the role of Chair of the Conference, and I hope to build onthe successes and accomplishments of the past conferences.

This year's conference will focus on certain themes that highlight our role in servingpriorities of our local community. These themes can be summarized as follows: Primaryhealthcare system, obesity, smoking, genetic disorders, and zoonotic diseases in Jordan.Accordingly, our slogan for the conference is: "JUST to Adjust your Health: Time to GiveBack to the Community". We are privileged this year to collaborate with a number ofdistinguished governmental and non-governmental organizations energetically operating inthe public health domain in Jordan; including the Eastern Mediterranean Public HealthNetwork (EMPHNet), Jordanian Public Health Society, the WHO Regional Office for theEastern Mediterranean (EMRO), the World Organization of Family Doctors (WONCA), theJordanian Society of Family Medicine, and Jordan Society for Obesity Treatment. Moreover,our medical students at JUST have had a great contribution to this conference, starting fromthe early phases of planning and preparation throughout the final stages of organization.This is why we are delighted to have a special session for them in the conference entitled:"Students Have Their Say". I am sure you will enjoy their involvement.

Dear Colleagues;

We thank our long-life partners in the Ministry of Health, Royal Medical Services, and otherinstitutions who have been always in support of the cause, mission, and vision of our Faculty.I wish you all a great scientific, academic, and cultural experience in our conference, andwould like to see you again in the upcoming events of our Faculty.

Best wishes

Wail Hayajneh, MD

Dean, Faculty of Medicine 111

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Conference Program

WEDNESDAY 18-October-2017

Opening Ceremony Al-Zahrawi Hall – KAUH

8:15 – 8:55 Registration

9:00

- National Anthem

- Holy Quran: Dr. Obada Al-Ali

Opening Remarks:

- Hosts: Dr. Laila Ababneh

Dr. Ahmad Altarifi

9:10 KAUH Speech: Prof. Ismail Matalka; CEO of KAUH

9:15 Opening Speech: Dr. Wail Hayajneh; Dean FMJUST, Chair of Conference

9:20 Welcome Speech: Prof. Omar Al-Jarrah; President of JUST

9:25keynote Talk:

تطوير نظامنا الصحي من خالل رفع كفاءة الطبيب األردني وخبراته العلمية والعملية

Prof. Nidal Younes, CEO of Jordan Medical Council (JMC)

9:50 - 10:00 Launch of the Posters and Booths Area

10:00 - 12:00 Bariatric Surgery for Obesity: A Community Necessity?

Organizer: Dr. Tagleb MazahrehModerators: Prof. Abdelkarim Alomari (JUST), Prof. Fawaz Ammari (JUST), Prof.

Hussein Heiss (JUST)10:00-10:20 Long-term effects of bariatric procedures on co-

morbidity

Dr. Sami Salem (Private sector)

10:20-10:40 Bariatric surgery in 2017: Experience of an Italian

referral center

Dr. Enrico Facchiano (Azienda

Sanitaria di Firenze – Italy)

10:40-11:00 One Anastomosis Gastric Bypass (OAGBP) as a revision

procedure for weight gain after previous surgery. A

personal experience presentation

Dr. Khalil Zayadin (Private sector)

11:00-11:20 Post-sleeve gastrectomy leak. Our experience at King

Hussein Medical Center

Dr. Wael Al-Naasan (KHMC)

11:20-11:40 Long-term effect of bariatric surgery: Resolution of

diabetes and comorbidities

Dr. Ashraf Haddad (Private

sector)

11:40-11:50 Gastric band complications; case report and review of

the present role of gastric banding in bariatric surgery

Dr. Ghazi Gasaimeh (JUST)

11:50-12:00 Open Discussion

12:00-12:15 Coffee Break

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3:15 - 5:00 Zoonotic Diseases as the Most Emergent Threat to Global Health Security

12:15 - 2:15 Towards a Smoking-Free Community in Jordan

7:00Gala Dinner

Organizer: Eastern Mediterranean Public Health Network (EMPHNet)Moderators: Prof. Hashem Jaddou (JUST), Dr. Wail Hayajneh (JUST), Dr. Ziad

Elnasser (JUST)

3:15-3:30Overview of zoonotic diseases in the context of IHR and

One Health ApproachDr. Ezzeddine Mohsni

3:30-3:45The importance of detection, prevention, and response

to emerging and re-emerging infectious diseasesDr. Ekhlas Hailat

3:45-4:00Proposed solutions for improving zoonotic diseases

management and related best practices Prof. Ahmad Almajali (JUST)

4:00-4:05 Jordan’s experience with brucellosis Dr. Adel Belbaisi


4:50-5:00 Conclusions and Recommendations Dr. Mohannad Al Nsour

Organizer: Dr. Ashraf OweisModerators: Prof. Anwar Batieha (JUST), Dr. Suleiman Momani (JUST), Dr. Shaher

Samrah (JUST)

12:15-12:45

Health effects of tobacco use

(including secondhand smoke (SHS) exposure, 3rd hand

smoke exposure, infections)

Dr. Feras Hawari (KHCC)

12:45-12:55 Waterpipe smoking among youth in Jordan Dr. Khalid Kheirallah (JUST)

12:55-1:15 Addictive nature of tobacco smoke Mr. Eyad Ghonemat (KHCC)

1:15-1:30 Educational models (interactive session) Ms. Rawan Shehab (KHCC)

1:30-1:50 Benefits of quitting and ways to quit Mr. Eyad Ghonemat (KHCC)

1:50-2:05 Advances in the treatment of metastatic lung cancer Dr. Osama Alshari (JUST)


2:15-3:15 Lunch Break

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Running Theme: Poster SessionHospital Reception Area

11:00 - 1:00 Bringing Genetics Back to the Community

THURSDAY 19-October-2017

8:30 - 10:30 Primary Healthcare System in Jordan: An Overview

Organizer: Dr. Adi KhassawnehModerators: Prof. Yousef Khader (JUST), Dr. Mahmoud Abdallat (JPHS), Dr. Mai Hadidi (MoH)

8:30-8:40 Why family medicine? Prof. Mousa Al-Omary (JUST)


8:55-9:05 Primary health care for saving money

Dr. Mohamed Abdel Rasoul Al-

Tarawneh (Secretary General of

High Health Council, President of

Jordanian Society of Family

Medicine)


9:15-9:30Primary health care; Where are we and where are we

going?Prof. Anwar Batieha (JUST)


9:40-10:00Scaling up family practice in EMRO countries to achieve

universal health coverage

Dr. Mohamad Ibraheem

Tarawneh (President of WONCA

EMR)


10:30-11:00 Coffee Break

Organizer: Dr. Mahmoud AlfaqihModerators: Prof. Ismail Matalka (JUST), Prof. Nayef Gharybeh (JUST), Prof. Zeyad Bataineh

(JUST)

11:00-11:15Attitude of Jordanians toward genetic research, genetic

testing, and clinical trials Dr. Mamoun Ahram (JU)

11:15-11:30Knowledge and attitude of Jordanian physicians toward

Biochemistry and GeneticsDr. Mahmoud Alfaqih (JUST)

11:30-11:45Alkaptonuria in Jordan; experience with a rare genetic

disorder

Dr. Mohammad Al-Sbou (Mu'tah

University)

11:45-12:00 Panel Discussion

12:00-12:15The Use of GWAS for the discovery of disease-causing

genetic markers in Arabian populationsDr. Osama Al-Smadi (KHCC)

12:15-12:30Targeted next generation sequencing and its use in

clinical diagnosticsDr. Rowaida Al-Momani (JUST)

12:30-12:45Whole exome sequencing in children with global

developmental delayDr. Amira Al-Masri (JU)

12:45-1:00 Panel Discussion

1:00-2:00 Lunch Break

1:00 - 2:00 Arar Competition

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2:00 - 3:30 Students Have their Say

Moderator: Dr. Mohammad Al-Qudah2:00-2:20 Medical Research Abdallah Akouleh

2:20-2:40 A glimpse into the Future - Personalized Medicine Kenan Rijjal & Omar Rababah

2:40-3:00 Antibiotic Resistance Areen Dhoon & Farah Bani Hani

3:00-3:20 Who said what you are now is who you are? Sajeda Kailani

3:20-3:30 Allowed in the Past, Prohibited in the Present Ahmad Abu Ajeene

3:30-4:00 Closing Ceremony

Running Theme: Poster SessionHospital Reception Area

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KeynoteSpeaker

7

Keynote Speaker: Prof. Nidal Younes (MBBSc, MA, TSRF)

Consultant Endocrine Surgery

Faculty of Medicine/ University of Jordan

Diabetic Foot Specialist

National Center of Diabetes Endocrine

Disease and Genetics

CEO, Jordan Medical Council

Qualifications:

M.B, B.Sc. / Jordan

o Issued in June 1986 by Faculty of Medicine / University of

Jordan after a 6-year course (September 1980- June 1986)

License to Practice Medicine / Jordan

o Issued in May 1987 by Ministry of Health

MA in General Surgery

o Issued in June 1991 by the University of Jordan ( 4-year program

1987-1991)

Certificate of Specialization in general Surgery

o Issued in June 1991 by Jordan Medical Council

Certificate issued by Educational Commission for Foreign Medical

Graduate (ECFMG Certificate) / U.S.A

o Issued in March 1993 after passing the three components of

FMGEMS (Basic, Clinical and English)

Postdoctoral Research Fellow in Endocrine Surgery

o Issued in June 1995 by the University of Chicago - USA

T.S. Reeve fellowship in Endocrine surgery

o Issued in June in 1996 – University of Sydney-Australia

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Sessions

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Session 1: Bariatric Surgery for Obesity: A Community Necessity?

1. Long-term effects of bariatric procedures on co-morbidities.

The talk will highlight the personal experiences of Dr. Salem on the effects and

long-term results of the bariatric operations on diabetes mellitus type 2,

hypertension, hyperlipidemia, and joint pain patients with follow up periods

exceeding 5 years.

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Dr. Sami Salem• 1981: Secondary School Certificate Hamburg/ Germany

• 1982-1988: Medical School Hamburg/ Germany

• 1988-1994: General Surgery Training/ Hamburg, Germany

• 1995-2000: General Surgical Training and Trust Surgeon/

London, UK

• 1997: FRCS, UK

• 2004: Facharzt (Specialist Certificate Hamburg) for Surgery

and Registration in London as Consultant in the specialist

register)

• 2000: Consultant for Gastrointestinal and Obesity Surgery

in Germany and Jordan

• 2015: HAAD-licensed and working as HOD & Consultant for

Gastrointestinal and Bariatric Surgery (Abu Dhabi)

2. Bariatric surgery in 2017: experience of an Italian referral Center.

The objective of this presentation is to give an overview of the activity of bariatric surgery

of the Italian referral Center of Florence. The number of bariatric procedure has risen in the

last years worldwide. This tendency in confirmed in Italy and in our Bariatric Center of

Florence. The Center of Bariatric Surgery of Florence was founded in 1991 and the activity

started with gastric banding procedures; laparoscopy was started in 1995. Other procedures

were progressively performed, including biliopancreatic diversion, Roux-en-Y Gastric

Bypass, Sleeve Gastrectomies and, in the last years, Mini Gastric Bypass. The first

laparoscopic gastric bypass was performed in 2002. The Center of Florence was the first in

Italy to propose a multidisciplinary approach for the selection of the bariatric patients.

Actually, all patients are evaluated preoperatively by a multidisciplinary team of specialists

including a bariatric surgeon, a dietician, a psychiatrist, an anesthesiologist and, if needed,

an endocrinologist, a pneumologist and a cardiologist. Other specialists are available if

needed. The surgical activity of our Center is represented in great part by gastric bypass

procedure (about 80% out of the total number of bariatric procedures), Roux-en-Y or Mini

gastric bypass. The Roux-en-Y gastric bypass is actually performed using the Double Loop

Technique (Video). The MiniGastric Bypass is performed fashioning a long and narrow

gastric pouch and performing a gastro-jejunal side-to-side anastomosis at a variable distance

(150 to 220 cm) from the Treitz ligament (Video). All patients undergo an ERABS

(Enhanced Recovery after Bariatric Surgery) protocol. Our results in terms of complications

and weight loss are presented.

At the Referral Bariatric Center of Florence, different types of procedures are regularly

performed: Roux-en-Y Gastric Bypass, Mini Gastric Bypass, Sleeve Gastrectomy, Gastric

Banding and Biliopancreatic Diversion. Gastric Bypass represents about 80% of the total

number of bariatric procedures performed. This operation appears safe and effective with a

low rate of short and long-term complications and excellent results in terms of weight loss.

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Dr. Enrico Facchiano• M.D. degree from University of Rome in 2001.

• Accredited Trained Specialist in General Surgery at the

University of Perugia in 2007.

• Senior Registrar at the University of Paris VII – Louis

Mourier Hospital (France) in 2007 – 2011 with specific

training in Laparoscopic Surgery, Bariatric and

Metabolic Surgery, Cancer and Peritoneal

Carcinomatosis Surgery.

• General and Bariatric Surgeon at the Careggi University

Hospital of Florence in 2011 – 2014.

• Since 2011 General and Bariatric Surgeon at Santa

Maria Nuova Hospital – Florence.

• Ph.D. degree in Biomedical Science from the University

of Florence in 2017.

• Published several papers in international peer-reviewed

journals.

3. One Anastomosis Gastric Bypass (OAGBP) as a revision procedure for

weight gain after a previous surgery. A personal experience presentation.

Since 2005, OAGBP is mainly performed to reintroduce weight loss after failed

sleeve and band surgery. The technique is explained, 40% were available to follow up

due to the expatriate character of my patient. Parameter like EWL, complications are

presented. Conclusion, the mini gastric bypass is a good revision procedure with

excellent weight loss and a low complication rate if done correctly. As a

malabsorptive procedure although it needs a better follow up than RY bypass,

because of possible protein deficiency, vitamin and mineral poor absorption. Easier to

perform and reversibility is possible.

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Dr. Khalil Zayadin• 1975: M.D: Humboldt University Berlin Germany.

• 1975 - 1980: General surgical training, Charite and

Friedrichshain Hospital Berlin.

• 1980 - 1981: Research with Ph.D. in medicine. Topic:

acute pancreatitis.

• 1981 - 1982: Research fellow at Sidney Farber cancer

institute in Boston and visiting surgeon MGH, John

Hopkins, and Mayo clinic

• 1983 - Present: Private practice in Amman / Jordan,

Admission rights in all major private hospitals.

• Laparoscopic and obesity surgery mainly in Amman

Surgical Hospital

• Performed laparoscopic surgery as early as January

1991.

• All advancements in laparoscopic surgery were

pioneered by Dr. Zayadin in Jordan.

• Instructor for laparoscopic surgery in Middle Eastern

Countries.

4. Post-sleeve gastrectomy leak. Our experience at King Hussein Medical

Center.

Objective: To present our experience at King Hussein Medical Center in the

management of stapler line leak post sleeve gastrectomy.

Methods: This is a retrospective study done at King Hussein Medical Center

between August 2014 and August 2017. Eleven patients who developed staple line

leak post sleeve gastrectomy were managed, conservative or with other procedures

including exploration and redo surgery. Site of the leak, type of procedures, hospital

stay, and mortality were discussed.

Results: Eleven patients with leak were managed at our center, are 3 from our

patients and 8 referred to our center form other hospitals. Two patients were males

and 9 females. Ten patients the leak was at the gastroesophageal junction and one

patient at the body of the stomach. Primary suturing, stenting and drainage of

collection, converting to bypass and using a T-tube to make the fistula controlled

one, and chest tube with naso-jejunal feeding tube, partial TPN with or without stent,

these are the procedures used. Average hospital stay were 24 days between 5-60

days. All patients did will. No mortality.

Conclusion: Management of staple line leak post sleeve gastrectomy needs a

specialized center with experienced multidisciplinary team. Management needs long

time hospitalization, multiple procedures and intensive follow up of the patients. In

experienced hand the results are excellent.

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Dr. Wael Al Nassan• Consultant General, Laparoscopic & Bariatric Surgeon,

King Hussein Medical Center.

• Member of the Editorial Board of the Royal Medical

Services Journal, since March 2007.

• Associate Editor of the Royal Medical Services Journal,

since July 2013.

• Head of Laparoscopic Team and Obesity Unit at King

Hussein Medical Center, since March 2010.

• Board Examiner in Emergency Medicine, Jordan Medical

Council 2014- 2017

• Head of Surgery Department, Royal Medical Services

since 26 Jan 2016.

• Reviewer at the Jordan Medical Journal.

• Board Examiner in General Surgery, Jordan Medical

Council since June 2017.

6. Gastric band complications; case report and review of the

present role of gastric banding in bariatric surgery.

5. Long term effects of bariatric surgery. Resolution of diabetes and co-

morbidities.In this talk, we will explore the different weight loss theories. We will talk the long term

hormonal adaptation to weight loss and discuss the multiple compensatory mechanisms

encouraging weight regain. The factors and drivers of obesity were discussed both from an

environmental and genetic standpoint. The various surgical procedures will be discussed

with a focus on the laparoscopic sleeve gastrectomy and laparoscopic roux en-y gastric

bypass with delineation of their physiologic mechanisms of action. Mile stone studies that

describes the effects of Bariatric surgery on health and various comorbidities including

type II diabetes and cancer were reviewed including the Swedish obesity study and the

Utah Bariatric surgery study. Finally the 10 year outcomes of the gastric bypass will be

reviewed focusing on the remission and improvement rates of diabetes.

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Dr. Ashraf HaddadDr. Ashraf Haddad received his medical degree from the Jordan

University of Science and technology. He then moved to the

United Kingdom where he finished two years of basic surgical

training. Then, in his pursuit for excellence, Dr. Haddad moved

to the United States to complete his general surgery training at

St. Agnes Hospital in Baltimore, Maryland. During his training

Dr. Haddad's interest in the field of Minimally Invasive and

Bariatric surgery grew. He presented his research work in

numerous national and international meetings. Furthermore, Dr.

Haddad had numerous publications in prestigious journals in the

fields of Bariatric, Gastrointestinal and Pancreatic Surgery. After

completing his general surgery training, Dr. Haddad moved to

California to complete his Minimally Invasive, Advanced GI, and

Bariatric surgery fellowship at UCSF - Fresno under the tutelage

of Dr. Kelvin Higa and Dr. Keith Boone. During the time he spent

working with his mentor (Dr. Higa - one of the giants of Bariatric

surgery) Dr. Haddad developed his passion and attained his skills

for complex and revisional bariatric and gastrointestinal cases. In

2015 Dr. Haddad moved back to Amman to join his Colleagues at

GBMC. Dr. Haddad wants to deliver the highest standard of care

to his patients in a state of the art center

Dr. Ghazi Gasaimeh• Associate Professor of Surgery, Faculty of Medicine, Jordan

University of Science and Technology.

• British Fellowship in General Surgery, Urology and anesthesia

from Royal College of Surgeons of Edinburgh. 1993.

• Jordanian Board in General Surgery from Jordan Medical

Council, 1995.

• BSc. In Medicine and Surgery from the University of the

Punjab, 1976.

Session 2: Towards a Smoking-Free Community in

Jordan

This session will describe health effects related to tobacco use depending on

evidence-based research and will highlight the harms of second-hand smoke

exposure, as well as exposure to third-hand smoke, then will go through the benefits

of quitting and ways to quit. Of interest to the Middle Eastern region is the waterpipe

smoking. The pervasiveness of this phenomenon among youth in the Arab world will

be particularly underscored during the session. Discussion of the smoking-related risk

of lung cancers is also scheduled in the session.

Speakers:

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Dr. Feras HawariAs director of the Cancer Control Office at King Hussein

Cancer Center (KHCC), Dr. Feras Hawari plays a key role in

advancing tobacco control as a national priority in Jordan. He

is active in research on a variety of topic related to tobacco

control. Dr. Hawari established and leads the inpatient and

outpatient tobacco dependence treatment (TDT) programs at

KHCC and is a lead trainer on TDT and tobacco control in the

EMR. In addition to his role in the Cancer Control Office, Dr.

Hawari is the chief of the Pulmonary Critical Care Service and

director of the Respiratory Unit at KHCC. Dr, Hawari is board

certificate in internal medicine, clinical pharmacology,

pulmonary disease and critical care medicine and a fellow of

the American College of Chest Physicians, Prior to Joining

KHCC, Dr. Hawari worked with pulmonary and Critical Care

Medicine Branch at the U.S. National Heart, Lung and Blood

Institute at the National Institutes of Health.

Dr. Khalid Kheirallah• Associate Professor of Public Health and Community

Medicine.

• Ph.D. in Public Health from Tulane University, 2009.

• MSc, in Public Health from Tulane University, 2006.

• MSc. in Public Health from Jordan University of Science

and Technology, 2002.

• BSc. In Dentistry from Jordan University of Science and

Technology, 1999.

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Ms. Rawan ShihabHead of the Nutrition and Health Education at the Cancer

Control Office/ King Hussein Cancer Center (KHCC). Ms.

Shihab, Plays a key role in different projects at the cancer

control office as the smoke free-zone certificate program since

2014. And several research projects focusing on different

aspects of tobacco control. Developing programs and training of

counselors related to tobacco control and healthy lifestyle are

parts of her responsibilities. She is also, passionate about

spreading awareness about harms of tobacco use and healthy

lifestyle for cancer prevention for different age groups.

Mr. Iyad Ghonimat• Manager, Respiratory Services & Pulmonary Function Test

Lab and Tobacco Treatment Specialist (TTS) at King

Hussein Cancer Center (KHCC).

• Certified as Tobacco Control Specialist from Johns Hopkins

Bloomberg School of Public Health - USA.

• Mr. Ghonimat plays a key role as a trainer of Tobacco

Dependence Treatment (TDT) for the Expand Availability of

TDT Services in the EMR project plus taking an essential

part in research projects as author and co-author. He is

also, a surveyor for the Health Care Accreditation Council

(HCAC).

Session 3: Zoonotic Diseases as the Most Emergent

Threat to Global Health Security

Background

Protecting people’s health by combatting outbreaks and preventing their

international spread remains a national priority for all countries. Addressing

emerging and re-emerging zoonotic diseases as a health security issue will promote

rapid detection of novel biological threats as well as assist in identifying

contextualized solutions for the management of these diseases, both from a security

and safety perspective as well as from a disease control perspective.

The Eastern Mediterranean Public Health Network (EMPHNET) will hold a

roundtable discussion for the attendees of JUST’s conference as part of

EMPHNET’s efforts in strengthening response to zoonotic diseases. This

roundtable session will encourage discussions related to the impact of zoonotic

diseases on global health security, and explore opportunities for professionals

working on human and animal health to coordinate response activities.

Purpose

The roundtable discussion session will aim at improving zoonotic diseases

management and related best practices among both the human and animal health

sectors.

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Objectives

The session's specific objectives are to:

Present an overview of zoonotic diseases as public health events of

international concern

Provide an example from Jordan’s experience

Explore ways to strengthen the capacity of the public and veterinary health

systems to detect, report, and control emerging and re-emerging infectious diseases

Propose contextualized solutions for improving zoonotic diseases

management and related best practices

Description

The roundtable session will start with brief remarks from the invited panelists

to set the ground for the theme of the session and raise questions for discussion.

Panelists will briefly review major events and outbreaks that the world witnessed

since the beginning of the century such as SARS, MERS-CoV, H5N1, and Ebola.

They will highlight contributing factors related to the culture, behavior, demographic,

trade and traffic. Panelists will also highlight the importance of International Health

Regulations and countries capacity in preparedness and response. Jordan experience

will be presented as an example of an emergent threat from animals to humans, and

how there is a crucial need for inter-sectoral collaboration mechanisms such as an

integrated surveillance system for animal and human cases. The session will start

with a 30 to 45 minutes talk to set the scene, and will be followed by 75 minutes of

directed discussions.

Facilitators

EMPHNET’s subject matter experts and other interested JUST representative

who will initiate discussions with the audience by raising questions pertinent to the

objectives of the session.

Target Audience

This roundtable session will be open for all attendees of JUST’s Conference.

Participants of the discussions are expected to be medical and veterinary physicians

interested in the animal-human interface.

Language

Panelists will present in either English or Arabic and discussions can take

place in both languages.

EMPHNET educational material will also be provided during the roundtable discussion session (i.e. brucellosis brochures, relevant guidelines, etc.).

18

Speakers:

19

Session 4: Primary Healthcare System in Jordan

Primary care is the provision of integrated, accessible health care services by

clinicians who are accountable for addressing a large majority of personal health

care needs, developing a sustained partnership with patients, and practicing in the

context of family and community.”

Better Health Care

Primary care is the backbone of the health care system. Utilizing primary care

physicians puts an emphasis on the physician-patient relationship by shifting the

focus from physician-centered care to patient-centered care. An increase of one

primary care doctor per 10,000 people has been shown to result in:

5% decrease in outpatient visits

5.5% decrease in inpatient admissions

10.9% decrease in ER visits

7.2% decrease in surgeries

Better Access to Health Care

Urban and rural communities that have an adequate supply of primary care

providers experience lower infant mortality, higher birth weights, and

immunization rates at or above national standards, despite social disparities.

Evidence shows that primary care, in contrast to specialty care, is associated with

a more equitable distribution of health in populations--a finding that hold in both

national and international studies.

Lowering the Cost of Health Care

A primary care-based system may cost less because patients experience

fewer hospitalizations, less duplication of treatment, and more appropriate

use of technology.

U.S. adults who have a primary care physician accumulate 33% lower

health care-related costs.

Medicare spending is lower in states with more primary care physicians,

and these states also report more effective, higher-quality care.

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Family Medicine: At the Center of Primary Care

Family medicine aims to reintegrate and personalize health care for patients, who are

increasingly frustrated with the fragmented and complex health care system. It is a

deviation from physician-centered traditional models of care, such as specialist care.

The family medicine model of care seeks to provide patients with a personal medical

home through which they receive a full range of services within the context of a

continuing relationship with their family physician. Family physicians deliver acute,

chronic, and preventive care, either directly or indirectly through established

relationships with clinicians outside their practice.

Scaling up Family Practice in EMRO countries

Objective: To improve the quality of primary health care in the EMRO countries,

through a comprehensive program, assisting the EMRO countries to improve primary

and reproductive health care by strengthening the public and private provision of these

services,

Background: Family practice [FP] is defined as the health-care services provided by

family doctors and often supported by a multidisciplinary team; it is characterized by

comprehensive, continuous, coordinated, collaborative, personal, family-and

community oriented-services and provides comprehensive medical care with a

particular emphasis on the family unit.

The World Health Organization (WHO) in collaboration with WONCA is working on

accelerating the adoption of family practice in the countries of the Region. This means

that the requirements necessary for implementation should be in place: clear policies

and strategies; evidence-based information to ensure technical support; engagement of

the community; and the necessary mechanisms for patient follow-up

Challenges: The major challenges facing family practice approach in EMRO

countries includes diversity of human resources capacity, financing limitations and

weak organization. Policy-makers have limited awareness about the concept of family

practice, and there is an increasing tendency to rely on expensive technology. Poor

logistics management and distribution of health facilities and workforce, lack of

public–private partnerships, and a shortage of resources and incentives are major

challenges to the proper implementation of a family practice program. Among the

biggest challenges are the insufficiency of trained family physicians and the fact that

existing training programs are failing to meet the enormous need for those

practitioners to support primary care.

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Conclusions: Experience from across the world has shown that the family practice approach

can increase households’ access to a defined package of services at an affordable cost,

through trained and motivated family practice teams. Scale up Family Practice in EMRO

countries needs trained and motivated family practice teams that can ensure high-quality,

continuing and comprehensive primary care services for the individual and family across all

ages and both sexes.

22

Dr. Mohammed Abdel Rasoul Al-Tarawneh• Family medicine consultant.

• Secretary General of High Health Council, Jordan.

• President of Jordanian Society of Family Physicians.

• 2005 – 2008 Director of Cancer Prevention Directorate.

• 2003 – 2005 Director of Training & Education Directorate.

• 2002 – 2004 Counter Partner with PHCI Project/ USAIDs.

Prof. Mousa Al-Omary• Professor of Public Health and Community Medicine, Faculty of

Medicine, Jordan University of Science and Technology.

• BSC. In Medicine and Surgery from Mousul University, 1976.

• British Fellowship in Public Health from Royal College of

Physicians & Surgeons, 1999.

Dr. Mohammed TarawnehDr. Tarawneh has 25 years’ experience in PHC field in Royal Medical

Services of Jordan; as tutor, master trainer and examiner of the

family medicine residency program in the Royal Medical Services

(RMS). and 2 terms in Jordan Medical Council, he was a member of

the scientific committee in the faculty of medicine of M’uta'

University for 2 years where he worked as tutor for the medical

students, currently he is a family medicine consultant in the private

sector, published different papers in the field of Primary health care

in International and local medical journals. WHO EMRO temporary

advisor, and he is WONCA - EMR president for 2nd term from 2016 to

2018.

Prof. Anwar Batieha• Professor of Public Health and Community Medicine, Faculty of

Medicine, Jordan University of Science and Technology.

• Ph.D. in Public Health from Johns Hopkins University, 1992.

• MSc. In Public Health from Johns Hopkins University, 1989.

• BSc. In Medicine and Surgery from University of Alexandria,

1973.

Session 5: Bringing Genetics Back to the Community

1. Attitude of Jordanians toward genetic research, genetic testing, and

clinical trials.

Communities that have high rates of consanguineous marriages benefit from genetic

testing as it may reduce the rate and prevent hereditary diseases. Jordan has a high

rate of consanguineous marriages and have recently implemented premarital genetic

testing. Herein, the knowledge, practice, and attitudes of the public in Jordan

regarding genetic testing were investigated. Individuals (N = 3,196) were questioned

about the concepts of genetic testing and genetic counselors, if they underwent any

genetic tests, the type of test, the method of consenting to the test, as well as their

level of satisfaction with the privacy of the genetic testing service. Although almost

70 % of respondents knew the term "genetic testing," only 18 % had undergone

genetic testing, primarily the mandatory premarital test. In addition, there was a lack

of general knowledge about genetic counselors. Many of those who had genetic

testing (45 %) indicated they did not go through a consent process, and a lack of

consent was significantly related to dissatisfaction with the privacy of the service.

Going for routine health checkups was not significantly correlated with either actual

or potential uptake of genetic testing, suggesting health care providers do not play an

influential role in patients' testing decisions. Our results show a gap between the

knowledge and uptake of genetic testing and may help guide the design of effective

strategies to initiate successful genetic counseling and testing services.

23

Dr. Mamoun AhramDr. Mamoun Ahram is currently an Associate Professor at the

School of Medicine, The University of Jordan, and Head of the

Office of Research at Jordan University Hospital. He holds a PhD

degree in Cancer Biology from Wayne State University (USA) and

had received research training at the National Cancer Institute

(NCI) and the Pacific Northwest National Laboratory. Dr. Ahram

was the Director of the Biorepository and Bio-specimens

Research Unit and Head of the Proteomics Laboratory at the King

Hussein Institute for Biotechnology and Cancer (KHIBC). He is

actively engaged in elucidating the role of the androgen receptor

in breast cancer pathogenesis through a combination of cellular

and molecular biology techniques and gene expression profiling.

Dr. Mamoun is also interested in the mechanism(s) by which the

androgen receptor regulates microRNAs expression in breast

cancer cell lines and tissue specimens. Dr. Ahram published over

30 research articles, review articles, and book chapters in

different research areas. He also received several awards such as

the Best abstract at the 10th Middle East Best of San Antonio

Breast Cancer Symposium and a Scholar-in-Training Award by

the American Association for Cancer Research (AACR).

2. Knowledge and attitude of Jordanian physicians toward Biochemistry

and Genetics.

Biochemistry and Genetics are integral courses of the medical curriculum. Despite

the importance of having a solid background in these disciplines, studies found that

clinicians develop a negative attitude toward these courses during medical school.

Clinicians explain this by the lack of correlation between the concepts taught in these

courses with bedside teaching in the following years. This led many medical schools

to adopt an integrated system-based syllabus supplemented with clinical correlations

instead of teaching these courses independently. Medical schools in Jordan switched

to the integrated syllabus however, studies that evaluate the attitude of clinicians

toward Biochemistry and Genetics are lacking. To evaluate the knowledge of

physicians and their attitude toward Biochemistry and Genetics disciplines, a

structured questionnaire consisting of 40 statements was distributed to a random

sample of 616 clinicians practicing in private and governmental hospitals in Jordan.

Participants earned their MD or MBBS degree from Jordan or other countries and

were either interns, residents or specialists at the time of the study. In the

presentation, the result of the survey is discussed in the context of the current content

and teaching methods of the Biochemistry and Genetics curriculum and

recommendations are made based on the above results.

24

Dr. Mahmoud AlfaqihDr. Mahmoud A. Alfaqih is an Assistant Professor of Biochemistry

and Molecular Biology at the Jordan University of Science and

Technology (JUST). He received his PhD in Biochemistry from

Washington State University. Following his PhD, he trained in

nuclear receptor pharmacology and drug discovery as a

postdoctoral fellow at Duke University. His research integrates

epidemiologic methods with cell based experimental model

systems to understand the role of dietary and lifestyle factors in

disease progression and treatment. More recently, he gained

interest in the curriculum development of basic science courses

and the applications of different teaching models to enhance the

learning experience of undergraduate medical students in

Jordan. Dr. Alfaqih has received numerous awards and

scholarships including a scholarship from the Ministry of Higher

Education to fund his PhD studies, a scholarship from King

Hussein Institute for Biotechnology and Cancer (KHIBC) to fund

his postdoctoral degree, and a postdoctoral award from the

Department of Defense (DOD), USA. His research has appeared in

Journals like; Nature Reviews Urology, Cancer Research, BMC

Genetics and the Prostate. Dr. Alfaqih is a member of the

American Association of Cancer Research and The Endocrine

Society.

3. Alkaptonuria in Jordan; experience with a rare genetic disorder.

Alkaptonuria (AKU) is a very rare genetic disorder, characterized by a lack of

homogentisate 1, 2 dioxygenase enzyme, and causing excretion of homogentisic acid

(HGA) in the urine and the accumulation of HGA in connective tissues. Clinical

manifestations include dark urine, dark-black pigmentation of connective tissues

(ochronosis), and arthritis of large joints and the spine. The aims of the project were

to identify AKU patients in Jordan, create AKU patients registry and raise the

awareness about AKU among healthcare providers and the community. We identified

77 cases with AKU in Jordan (age range, 2 months-77 years), two third of the

patients were under the age of 30 years. The clinical, biochemical and genetic

findings will be presented. Achievements, international collaboration, challenges and

our future plans will also be discussed in the presentation. AKU research office and

Jordanian AKU society were established to support patients and their families.

4. The use of GWAS for the discovery of disease-causing genetic markers

in Arabian populations.

Despite a high prevalence of metabolic related disorders in populations of Arabic

descent, there is a lack of credible genetic determinants for these disorders. Arab

populations today are under-represented in global genome-wide association surveys.

The use of Genome Wide Association Studies (GWAS) for the identification of

genetic markers in metabolic disorders was used in many global studies, however it

wasn’t until recently that this powerful approach was used in regional studies which

focus on populations of Arabian ancestry. Both novel and common genomic variants

of genes/enzymes of key metabolic steps have surfaced as a result of these efforts.

Several examples of these findings and their implications will be presented and

discussed. 25

Dr. Mohammed Al-SbouDr. Mohammed Al-Sbou is an Associate Professor of Clinical

Pharmacology at the School of Medicine in Mutah University. He

is currently the chairman of the Department of Pharmacology. Dr

Al-Sbou is also the Chairman of the Health and Hazzard

Evaluation Committee at the Jordan Food and Drug

Administration (JFDA), the head of the Pharmacovigilance Centre

of Southern Jordan at Al-Karak governmental teaching hospital.

Dr Al-Sbou research focuses on the prevalence, and molecular

basis of rare genetic disorders. Dr Al-Sbou published several

articles on the genetic basis of Alkapatonuria and plays an active

role in educating the general public about this disease. His

efforts in this field are well recognized at the national and

international level as he is the chairman of Jordanian

Alkaptonuria Society and the head of “Alkaptonuria research” in

Jordan. Dr. Al-Sbou is also a member of the International

Alkaptonuria clinical trial team, and a co-ordinator of the FP7

project (DevelopAKUre Project) in Jordan established to find a

cure for Alkaptonuria.

5. Targeted next generation sequencing and its use in clinical diagnostics.

Next Generation Sequencing (NGS) has changed the way genomes are sequenced and led to a

decline in the cost of sequencing. However, routine sequencing of large numbers of whole

human genomes remains prohibitively expensive for clinical use. Nevertheless, we expect

that the use of this technology will become a routine practice in the near future. For the time

being, to fully leverage the power of NGS in a large number of samples in a cost-effective

manner, several targeted enrichment approaches are currently available to selectively enrich

genomic regions of interest before sequencing. Exome and targeted NGS approaches

facilitated the diagnosis of many genetic diseases, accelerated the identification of disease-

causing genes, and provided a systematic tool for the classification of previously intractable

genetic disorders. Based on the above, we believe that exome and targeted NGS can be

implemented as a routine diagnostic tool for the screening of many genetic diseases.

26

Dr. Osama AlsmadiDr. Alsmadi is currently the head of the Clinical Genomics and

Precision Medicine core facility at King Hussein Cancer Center

(KHCC). Prior to joining KHCC, Dr. Alsmadi was the Head of the

Dasman Genome Center in Kuwait. Dr. Alsmadi obtained his BS

in Medical Technology from Yarmouk University, and his

master’s and PhD degrees in Molecular Biology from New York

University. Throughout his career, Dr. Alsmadi established

several genomic facilities, assembled coherent research teams,

and developed several clinical research protocols. Dr. Alsmadi’s

research utilizes modern genomic technologies such as Next

Generation Sequencing (NGS) and Genome-Wide Association

Studies (GWAS), combined with computational tools, for the

analysis of human genome and exome data. His research has led

to the discovery of several disease causing genes of simple and

complex hereditary diseases. His research was published in

reputable international journals like the European Journal of

Medical Genetics, BMC Genomics and many others. Dr. Alsmadi

is a member of the American Diabetes Association and the

American Society of Human Genetics..

Dr. Rowaida AlmomaniDr. Almomani is currently an Assistant Professor in the Department of Medical

Laboratory Sciences, Jordan University of Science and Technology. Dr. Almomani

obtained her B.S. in biology from Mu’tah University with honors in 2002, her master’s

degree in applied biology/human Genetics in 2005 from Jordan University of Science

and Technology, and her doctorate in human Genetics from Leiden University in the

Netherlands. She did two post-doctoral fellowships, the first was in the Department of

Human Genetics at the University of Groningen and the second in the Department of

Clinical Genetics and Cell Biology at Maastricht University, the Netherlands. Dr.

Almomani was a member of the Neuromuscular Diseases Center Maastricht

(Spierziekten Centrum Maastricht) from January 2015- May 2017. She also was a Work

Package leader in an international collaborative project, the PROPANE study. Dr.

Almomani is interested in the application of new genomic technologies to understand

the basis of genetic disorders. In her research, she establishes and applies state of the

art technologies, such as targeted and exome next generation sequencing, for the

identification of genes and genetic variants linked with hereditary disorders.

6. Whole exome sequencing in children with global developmental delay.

Genetic diagnosis of children with global developmental delay (GDD) and

intellectual disabilities remains a major challenge in clinical genetics. In only around

40-60% of patients with GDD a specific molecular etiology can be identified through

traditional testing techniques which include neuroimaging, metabolic work up,

chromosomal analysis and single gene testing for known genetic disorders. In

countries with high rates of consanguineous marriages, consanguinity is a major risk

factor contributing to the prevalence of GDD. Accurate diagnosis is not only essential

in determining therapeutic options and prognosis for children with GDD, but is also

important for estimating the risks of recurrence for the family and in establishing the

priorities for future national prevention and care programs. Whole exome sequencing

(WES) is a high-throughput genetic sequencing method that only sequences the

protein-coding regions of the human genome. Its application in clinical genetics

represented a breakthrough that resulted in an increase in the diagnosis rate of

children with GDD. The implications and benefits of using WES in this category of

patients will be discussed in the presentation.

27

Dr. Amira Al-MasriDr. Amira Al-Masri is a Professor of Pediatric Neurology at

the University of Jordan. She completed her residency in

General Pediatrics at the Jordan University Hospital.

Following her residency, she trained in Pediatric Neurology

in Montpellier/France. Dr. Al-Masri also holds a master’s

degree in the management of epileptic patients from Sfax

University in Tunisia. Dr. Al-Masri is an active member of

several committees at the Jordan University Hospital and

the School of Medicine including the residency and

internship-training committees. Dr. Al-Masri was also the

program director of the Pediatric residency program for

several years. Dr. Al-Masri’s research uses state of the art

genomic technologies to identify genes linked with

neurological abnormalities in children including a role for

hereditary factors in explaining global developmental delay

in pediatric patients. Her research has appeared in Science,

The Journal of Biological Chemistry, the American Journal

of Human Genetics and several other prestigious journals.

Dr. Al-Masri is a member of the European Pediatric

Neurology society, the International Child Neurology

Association and several other local and international

associations.

PosterSessions

28

Poster Sessions

29

Title Presenting Author Discipline

Human aldehyde dehydrogenase 7A1 (ALDH7A1)

expression affects cancer cell proliferation, migration and

cell protection against oxidative stress

Dr. Lina Elsalem Pharmacology

Symptoms and Risk of Obstructive Sleep Apnea and the

Risk of Coronary Artery Disease: The Findings of Berlin

Sleep Questionnaire

Dr. Ali Ibnian Medicine

Iatrogenic lung collapse in a neonate after recurrent

intubations and tracheal suctioning Dr. Ahmad Al OmariENT

Primary sino-orbital peripheral T-cell lymphoma presenting

as a unilateral peri-orbital swelling

Effect of insulin on neurotrophins' levels in the muscular

wall of mice intestineDr. Mohammad Alqudah Physiology

Evaluation of swimming exercise with and without Non-

Steroidal Anti-Inflammatory Drugs on inflammatory

nociception in rats

Zain Kalha Pharmacology

The effect of different doses of androgen treatment on the

total body weight of female ratsDr. Nasr Alrabadi Pharmacology

The effect of different doses of androgen treatment on the

total body weight of male rats

An audit of cesarean sections in tertiary university hospital

in north of JordanDr. Hashem Yaseen OB/GYN

The Relationship between Type II Diabetes Mellitus and

Clinical Depression in Primary Care Practice in Northern

Jordan

Renad Abunaser Pharmacology

Paraneoplastic panniculitisKhaleel Abdul kareem

AlqararhaRadiology

Location and Histologic Features of Colonic Polyps: Review

of 6000 polyps colonoscopies and 600 polypsKhalid Rashid Al-Alawi Student

CT-measured Subcutaneous and Visceral Fat in Patients

with Colorectal Cancer

Depression, Anxiety, and Sexual Dysfunction among

Jordanian Women with Type 2 Diabetes MellitusZaina Alazawi Ministry of Health

The impact of previous cesarean section on the outcome in

patients with non-adherent placenta previaAreen Al Na’san OB/GYN

Viral Surveillance of Hospitalized Children with Acute

Respiratory Infection in Northern JordanDr. Samah Awad Pediatrics

ABO Blood Groups and Lung Cancer Anas zaitoun Pathology

Unhealthy eating habits among adolescent waterpipe

smokers

Dr. Nihaya Al-sheyab NursingAssociations of cigarette and waterpipe smoking with

asthma and wheezing among Jordanian adolescents

Abstracts

30

Name: Lina Elsalem

Title: Dr.

Primary Affiliation: Department of Pharmacology

Address: Faculty of Medicine

Email: [email protected]

Other authors: Anaxagoras Fotopoulos, Athanasios Papathanasiou, Simon

Allison, Jan Moreb, Zoe Cournia, Klaus Pors

Abstract title: Human aldehyde dehydrogenase 7A1 (ALDH7A1) expression affects cancer cell proliferation, migration and cell protection against oxidative stress

Keywords: ALDH7A1, proliferation, migration, ROS

31

Introduction ALDH7A1 has important antioxidant role against oxidative stress causedby reactive oxygen species (ROS). Abnormally high expression of ALDH7A1 has beenfound in ovarian cancer, prostate cancer and matched bone metastasis, while itsexpression in NSCLC has been linked with cancer recurrence. Most of these studiesconcern the expression of ALDH7A1 but relatively little is known about its biologicalroles in cancer. Here, we report on the implication of ALDH7A1 expression in cellproliferation, migration and protection against ROS. Materials and Methods H1299, aNSCLC cell line that has low endogenous ALDH expression was stably transducedwith ALDH7A1. The gene and protein expression was evaluated in H1299/7A1 andH1299/RFP cells using qRT-PCR and western blot, respectively. ALDH activity wasmeasured with ALDEFLUOR assay. MTT assay was used to study cell proliferation,while cell migration was measured with scratch assay. ROS generation was detectedusing carboxy-H2DCFDA and dsDNA breaks were measured using the expression ofphosphorylated H2AX protein. The anti-proliferative effect of anticancer drugs wasevaluated using MTT assay. Results and Discussion ALDH7A1 was found to be highlyexpressed in H1299/7A1 at both the gene (85-fold) and protein (9-fold) levelscompared to H1299/RFP cells. ALDH activity was 17-fold higher in H1299/7A1 thanH1299/RFP. ALDH7A1 enhanced H1299 cell proliferation and migration. In addition, itsignificantly reduced the generation of ROS (>90%). H1299/7A1 cells hadsignificantly less phosphorylated H2AX expression (>70%), indicating that ALDH7A1was protecting cells against DNA damage caused by ROS. The effect ofcomputationally designed compounds on ROS generation showed that ICT11501resulted in significant more ROS in H1299/7A1 cells, suggesting inhibition ofALDH7A1 functional activity. No difference in the cell survival of both H1299 cells wasfound upon treatment with cytotoxic and molecularly targeted drugs. Conclusion Ourdata revealed a possible role of ALDH7A1 in mediating cell proliferation andmigration. This the first study describing an antioxidant role of ALDH7A1 in thecontext of cancer.

Abstract:

Abstract:

Introduction: Obstructive sleep apnea (OSA) is the most common sleep -breathingrelated disorder and coronary artery disease (CAD) is a leading cause of morbidityand mortality. The aim of this study is to describe the prevalence of symptoms andrisk of OSA in patients undergoing cardiac catheterization (CATH) and theircontribution to CAD risk. Methods: A cross sectional study of adult patients whounderwent CATH for ischemic heart disease. Patients are considered to have CAD ifthey have ≥ 50% luminal stenosis in ≥ 1 coronary vessel. Patients with minimal orno stenosis were considered normal and served as the control group (CONTROLS).Berlin Questionnaire was used to record symptoms and risk of OSA. Snoring, daytimesleepiness and high-risk of OSA were studied as potential risk factors for CAD.Results: a total of 398 patients completed the study, their mean age was 58.7 years(range, 21-92) and 68.6% were males. Snoring was reported by 61% of patients and36% had daytime fatigue and tiredness. Almost half (44.2%) had high-risk of OSA.CAD was present in 265 (66.6) patients. Prevalence of symptoms and high-risk ofOSA was not different between patients with CAD and CONTROLS. After adjustingfor known risk factors for CAD, snoring [OR 1.2 (CI 0.75-1.88)], daytime sleepinessor fatigue [OR 1.2 (CI 0.7-2.2)] and being at high-risk for OSA [OR 0.96 (CI 0.61-1.48)] were not associated with CAD risk, p > 0.20. Conclusion: symptoms and high-risk of OSA were common among patients undergoing coronary catheterization buthas no association with CAD. These patients should be screened for OSA andappropriately diagnosed.

Name: Ali Ibnian

Title: Dr.

Primary Affiliation:Jordan university of Science and technology/Faculty of

Medicine/Internal Medicine department

Address: Suleiman Al Qanouni street/alrawdah/ Irbid/ Jordan


Other authors: Basheer Khassawneh (Main author), Moammad Jarrah,

Rasheed Ibdah

Abstract title:Symptoms and Risk of Obstructive Sleep Apnea and the

Risk of Coronary Artery Disease: The Findings of Berlin

Sleep Questionnaire

Keywords: coronary artery disease, risk, obstructive sleep apnea,

snoring, sleepiness, Berlin questionnaire

32

Abstract:

Name: Ahmad Issa Al Omari

Title: Dr.

Primary Affiliation: JUST

Address: Amman - Jordan


Other authors: Mohammad Alsalem, Mahmoud Tanash

Abstract title: Iatrogenic lung collapse in a neonate

after recurrent intubations and tracheal

suctioning

Keywords: Case report, Lung collapse, Bronchial

obstruction, Granulation tissue,

endotracheal tube.

Iatrogenic lung collapse due to complete main stem bronchus obstructioncaused by recurrent intubations and repetitive tracheal toileting has beenrarely reported in literatures. The early diagnosis and proper management areimperative to avoid mortality. In this case we will present a case of 1-month-old boy, weighing 3 kg, who developed a complete right main bronchusobstruction by granulation tissue leading to right lung collapse a complete rightlung collapse after multiple intubations and prolonged pediatric ICU admissiondue to respiratory distress syndrome (RDS). Removal of the granulation tissuewas completely successful using a rigid bronchoscope and cold steelinstruments. We concluded that a careful atraumatic intubation should beattempted in all patients with extra care in neonatal age group. AnExperienced doctor or experienced attentive pediatric ICU nurses shouldhandle the bronchial suctioning of neonates to avoid trauma to the trachealstructures. A bronchial obstruction that may result in lung collapse should besuspected after traumatic or prolonged intubation or frequent airwaysuctioning, where the early diagnosis and proper management are imperativeto avoid mortality.

33

Abstract:

Name: Ahmad Issa Al Omari

Title: Dr.


Address: Amman - Jordan


Other authors: Mohammad Alsalem, Mahmoud Tanash,

Mohammad Al amri

Abstract title: Primary sino-orbital peripheral T-cell lymphoma

presenting as a unilateral peri-orbital swelling

Keywords: Sino-orbital lymphoma, Sino-orbital tumor,

Lympho-proliferative, T-cell lymphoma,

Ophthalmoplegia.

Primary sino-orbital lymphomas are part of the lympho-proliferative lesions thataffect the nasal cavity and the para-nasal sinuses and the orbit. Sino-nasal andorbital lymphomas may co-exist, however the vast majority are lymphomas of B-cell lineage which also show more associated with orbital extension. Here wereport a 57-year-old man presented with a progressive unilateral periorbitalswelling with subsequently rapidly progressive ophthalmoplegia due to primarysino-orbital peripheral T-cell lymphoma. To our best knowledge, this is the firstcase of primary sino-orbital peripheral T-cell lymphoma to be reported in themiddle-east.

34

Abstract:

Name: Mohammad Alqudah

Title: PhD

Primary Affiliation: Jordan University of Science and Technology

Address: Jordan University of Science and Technology


Other authors: Ayman Mustafa, Othman Al-shboul, Ahmed

Aldwairi

Abstract title: Effect of insulin on neurotrophins' levels in the

muscular wall of mice intestine

Keywords: neurotrophins, Insulin, Gut

Background: Neurotrophins are implicated in the physiology andpathophysiology of the mature gastrointestinal tract (GIT) such as motility andinflammatory bowel disease. Moreover, GIT disturbances has been attributed tohyperinsuliemia. Insulin-neurotrophins interactions in the (GIT) have not beeninvestigated yet. Aim: To test the effect of Insulin on the expression ofneurotrophins in the muscular wall of mice intestine and colon. Methods: Totalprotein extracts from intestinal and colonic muscular wall treated for 24 hourswith insulin were subjected to ELISA assays specific for different neurotrophinsand data were analyzed using suitable statistical test with graph pad. Results:insulin treatment resulted in significant reduction of neurotrophin-3 (NT-3)protein levels in the muscular wall of both mice intestine and colon. Moreover,neurotrophin-4 (NT-4) levels were significantly reduced in response to insulintreatment in muscular tissue from both intestine and clone as well.Interestingly the effect of insulin was more profound in the colon on NT-3 andNT-4. Conclusion: These results indicate that changes in GIT structure andfunction seen in hyperinsulinemia might be due to the effect of insulin onneurotrophins expression levels. However, functional studies are needed toelucidate the exact interactions between insulin and neurotrophins in the GIT.

35

Abstract:

Name: Zain Ahmad Kalha

Title: MSc.

Primary Affiliation: Department of pharmacology, School of midicine,

Jordan University of science and technology

Address: 6, Al naim street, Al Rawnaq, Amman , Jordan


Other authors: Dr. Saddam Fuad Kana'an, Dr. Karem Hasan Al-

Zoubi, Dr. Mahmoud A. Alfaqih, Dr. Abdallah Adel

Alzoubi, Dr. Ahmad Adnan Altarifi

Abstract title: Evaluation of swimming exercise with and

without Non-Steroidal Anti-Inflammatory Drugs

on inflammatory nociception in rats

Keywords: Pain; Complete Freund’s Adjuvant; Ibuprofen;

Swimming; Exercise

Pain is a growing health problem with increasing prevalence and burden worldwide.Major approaches for pain control include pharmacological and non-pharmacologicalinterventions. Pharmacological treatment is achieved by the use of analgesics suchas non-steroidal anti-inflammatory drugs (NSAIDs) and opioids that are accompaniedwith many side effects upon prolonged use. Physical exercise is an example of non-pharmacological interventions for pain control. We studied the effect of one of themost commonly prescribed NSAIDs, ibuprofen, on nociception threshold in rats withand without the addition of swimming exercise. Nociception was induced by theintraplantar injection of Complete Freund’s Adjuvant (CFA). The goal of this studywas to determine the effect of adding swimming exercise on nociception thresholdand on ibuprofen-induced antinociception in inflammatory pain rat model. Wehypothesize that swimming exercise will enhance the ibuprofen-inducedantinociception in rats. Ibuprofen produced an antinociception effect only at thehighest dose used (32mg/kg) with inflammation lasting for 17 days. Antinociceptionwas significantly higher in swimming treatment and prophylactic swimming groupswhen compared to ibuprofen alone, at the dose of 32 mg/kg in both groups and at10 mg/kg in the prophylactic swimming group alone. The duration of inflammationdid not exceed 7 days in both swimming groups. In conclusion, the combination ofibuprofen and swimming exercise was shown to be effective in controllingnociception in a rat pain model. The combination of exercise and ibuprofen could besuggested as an effective intervention to help control chronic pain problem. Inaddition, prophylactic swimming could be added to ibuprofen to increase its effectwhile lowering its dose used thus lowering the multiple ibuprofen-induced sideeffects. 36

Abstract:

Name: Nasr Alrabadi

Title: Dr (MD, M.Phil, PhD)

Primary Affiliation: Department of Pharmacology, Faculty of Medicine, Jordan

University of Science and Technology

Address: Department of Pharmacology, Faculty of Medicine, Jordan

University of Science and Technology, Irbid, Jordan.


Other authors: Haneen Sarairah, Rasha Maraqah, Mohammad Al-qudah

Abstract title: The effect of different doses of androgen treatment on the

total body weight of female rats.

Keywords: Androgen, Sustanon, body weight, female rats

The data presented is part of the work of a currently enrolled master students Title:The effect of different doses of androgen treatment on the total body weight offemale rats. Authors: Nasr Alrabadi, Haneen Sarairah, Rasha Maraqah, MohammadAlqudah. Background: Androgens are natural and essential hormones in thedevelopment and function of body organs. As well, these hormones can bemanufactured and administered to the body aiming to treat different pathologicalconditions. Anabolic steroids are forms of these manufactured androgens which areexcessively used by body builders aiming to gain excessive muscle weight andstrength. However, the abuse of anabolic steroids is associated with variety ofcatastrophic complications. This dose-dependent effect especially with thedifferences in the prevalence and prognosis of androgen related diseases betweendifferent sexes, can indicate to dose and sex-dependent paradoxical effects of thesehormones. Aim: To determine the effect of different doses of sustanon(manufactured androgen) on the total body weight of female rats. Methods: 36Female Wister rats were randomly housed in 6 separate groups. Each group receiveddifferent doses of sustanon treatment (1, 3.2, 10, 32 and 100 mg/kg/week) orvehicle. Each rat received 6 serial intra-muscular injections of sustanon with oneweek interval between injections. Total body weight was obtained weekly for each ofthese female rats. Results: Our data suggested that some of the sustanontreatments (1 and 100 mg/kg/week) were not able to cause any change in the totalbody weight of the female rats when compared to the control animals over thecourse of the treatment (6 weeks). However, moderate doses (3.2, 10 and 32mg/kg/week) appeared to be able to cause a significant increase in total body weightat the end of the course of the treatment. Of interest, the increase in the bodyweight was also associated with increase in the aggressiveness of the animals.Conclusions: Moderate sustanon doses (3.2, 10 and 32 mg/kg/week) appeared to beable to cause a significant increase in total body weight after one month ofcontinuous treatment. This increase appeared to be associated with increase in theaggressiveness of the animals. 37

Abstract:

Name: Nasr Alrabadi

Title: Dr (MD, M.Phil, PhD)

Primary

Affiliation:

Department of Pharmacology, Faculty of Medicine, Jordan


Address: Department of Pharmacology, Faculty of Medicine, Jordan

University of Science and Technology, Irbid, Jordan.


Other authors: Rasha Maraqah, Haneen Sarairah, Alaa Majd, Mohammad Al-

qudah

Abstract title: The effect of different doses of androgen treatment on the

total body weight of male rats.

Keywords: Androgen, Sustanon, body weight, male rats

The data presented is part of the work of a currently enrolled master students Title:The effect of different doses of androgen treatment on the total body weight of malerats. Authors: Nasr Alrabadi, Rasha Maraqah, Haneen Sarairah, Alaa Majd,Mohammad Alqudah. Background: Androgens are natural and essential hormones inthe development and function of body organs. As well, these hormones can bemanufactured and administered to the body aiming to treat different pathologicalconditions. Anabolic steroids are forms of these manufactured androgens which areexcessively used by body builders aiming to gain excessive muscle weight andstrength. However, the abuse of anabolic steroids is associated with variety ofcatastrophic complications. This dose-dependent effect especially with thedifferences in the prevalence and prognosis of androgen related diseases betweendifferent sexes, can indicate to dose and sex-dependent paradoxical effects of thesehormones. Aim: To determine the effect of different doses of sustanon(manufactured androgen) on the total body weight of male rats. Methods: 36 MaleWister rats were randomly housed in 6 separate groups. Each group receiveddifferent doses of sustanon treatment (1, 3.2, 10, 32 and 100 mg/kg/week) orvehicle. Each rat received 6 serial intra-muscular injections of sustanon with oneweek interval between injections. Total body weight was obtained weekly for each ofthese male rats. Results: Our data suggested that the sustanon treatment was notable to cause any change in the total body weight of the male rats when comparedto the control animals. Neither the physiological, supra-physiological or toxic doseswere able to cause any weight changes. Conclusions and future directions: Sustanontreatment may not be able to alter the total body weight. However, it is possible thatit may increase the muscle but decrease the fat proportion of the body weight whichwill be further investigated in the future.

38

Name: Hashem M Yaseen

Title: MBBS , 5th year of higher speciality in obstetrics and gynecology

Primary

Affiliation:Department of Obstetrics and Gynecology, King Abdullah

University Hospital

Address: King Abdullah University Hospital, Jordan University of Science and

Technology (JUST).


Other

authors:N. Obeidat, H. Alchalabi

Abstract

title:An audit of cesarean sections in tertiary university hospital in north

of Jordan

Keywords: cesarean sections rate, VBAC, Audit

39

Abstract:

Objective: To analyze the rate and frequency of different indications of cesareansections in KAUH, and to determine the range and determinants of CSR.Introduction: In 2004, rate of CSR in Jordan showed increase in the period 1999-2001 (8% to 10.9%), though WHO reported in 2010 that the rate is 18.5%.Methods: This is cross sectional study from October to December 2015. A total of820 pregnant females delivered during that period were enrolled in the study. Clinicalrecord of all patients were analyzed in terms of percentage and frequency. Datapertaining to infants less than 24 weeks of gestation were excluded. Results: Thetotal number of deliveries during the three-month study period is 820 cases. Vaginaldelivery rate was 46.7 %, and CSR was 52.6 % (20% Primary and 33% repeated).The most frequently cited indication for CS is previous CS. The reported percentageof CS for this indication is around 36%. Maternal request is the second mostcommonly cited reason for performing a CS. But 51 cases of maternal request(64.6%) have one previous CS, and they asked for CS directly without trial of labor,which means that 35.4 % of cases were primarily performed for maternal request(28 of cases). The overall CSR among women who had induction of labor was about34%. Among primigravid women, the CSR was 43%, and among multiparous womenwith no previous CS it was 16%. The most influential factor in deciding to performthese CS was presumed fetal compromise (48% cases). Conclusion: The overall rateof cesarean section in our study was 52.6 % and the most common indication wasrepeat cesarean section 36%. The rate of primary cesarean section was 20% (10%from all deliveries) and the most common indication was presumed fetalcompromised 16%.

Name: Renad Abunaser

Title: Master graduate student

Primary Affiliation: Jordan University of Science and Technology

Address: Department of Pharmacology, School of Medicine, Jordan



Other authors: Dr. Abdallah Alzoubi, Dr. Adi Khassawsneh, Dr. Aws Khasawneh

Abstract title: The Relationship between Type II Diabetes Mellitus and Clinical

Depression in Primary Care Practice in Northern Jordan

Keywords: Depression, Type 2 Diabetes mellitus, Bidirectional

Relationship

40

Abstract:

Background: Diabetes is a major health problem that affects 8.5% of adultsworldwide, and 13.1% of adults in Jordan. Conflicting evidence exists on thebidirectional relationship between diabetes and clinical depression. Because little isknown about the bidirectional relationship between diabetes and clinical depressionin Jordan, we aimed to determine the prevalence of depression among Jordaniandiabetic patients, as well as the prevalence of diabetes among Jordanian depressedpatients, and to examine the effect of treating depression on metabolic controlparameters in diabetic patients. Methods: Jordanian patients were enrolled in across-sectional two-armed screening study to determine the link between depressionand type 2 diabetes mellitus (T2DM) in primary care practice. We screened fordepressive symptoms among T2DM patients (n=148) using the patient healthquestionnaire-9 (PHQ-9), while we screened for diabetes among depressedindividuals (n=30) by measuring their glycated hemoglobin (HbA1c). Metaboliccontrol was assessed by measurement of HbA1c, triglycerides, cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels. Clinicallydepressed patients who were deemed eligible for pharmacological treatment wereadministered escitalopram 10 mg orally once daily for three months (interventioncohort). Results: The prevalence of moderate to severe depressive symptoms amongT2DM patients, according to PHQ-9, was 31.76%, while the prevalence of clinicaldepression based on interview was 11.49%. The prevalence of newly diagnosedT2DM among depressed individuals was 6.67%. Baseline PHQ-9 scores correlatedsignificantly with baseline levels of HbA1c, HDL, and triglyceride levels in T2DMpatients. However, we failed to find an association between PHQ-9 scores and HbA1clevels among depressed individuals. Escitalopram treatment resulted in significantimprovement of depressive symptoms among diabetic patients, without significantlyimproving any of the metabolic control measures. Conclusion: Depression is commonamong T2DM. The relationship between clinical depression and T2DM in the contextof metabolic syndrome is plausible.

Abstract:

Name: Khaleel Abdul kareem Alqararha

Title: 4th year resident in radiology


Address: P.O.Box 3030 Irbid 22110 Jordan


Other authors: Dr. Ma'moon Al-Omari, A. Professor - Faculty of

Medicine

Abstract title: Paraneoplastic panniculitis

Keywords: Panniculitis , paraneoplastic, CT scan

Aim: To determine the prevalence of known malignancy in patients with CTfinding of panniculitis. Material and methods: Retrospective analysis of allpatients with evidence of panniculitis on CT scan over a period of two years(8/2015 to 7/2017). Total numbers of 170 patients with evidence of panniculitison CT scan, age (25-85) mean age 53y, 102 male (60%), 68 female (40%).Known malignancy: Lymphoma, breast CA, pancreatic CA, colon CA, BladderCA, CML. Results: On analysis of data lymphoma was appreciated in 15 patientsof our group, with prevalence = 8%. Breast CA was appreciated in 6 patients ofour group, with prevalence = 3.5%. Colon CA was appreciated in 6 patients ofour group, with prevalence = 3.5%. Bladder CA was appreciated in 2 patientsof our group with prevalence = 1.2%. Pancreatic CA was appreciated in 2patients of our group with prevalence = 1.2% CML was appreciated in 1patients of our group with prevalence = 0.5 %. No known malignancy wasappreciated in 86 patients of our group with prevalence = 81.2%. Conclusion:The prevalence of malignant tumors in patients diagnosed with panniculitis inour study was 18.8% with lymphoma being the most common type ofmalignant tumors with prevalence = 8%.

41

Abstract:

AIMS: The true prevalence of colonic polyp is unknown. We aim in this study todetermine the prevalence location and histologic features of colonic polyps.METHODS: This is a retrospective study conducted at King Abdullah UniversityHospital. Database of the histopathology department for the period (2009 – 2015)was searched for colonic polyps. Then, colonoscopy database of the endoscopy unitewas searched for their sizes and locations in the colon. Patients’ demographic dataand indication for colonoscopy were also recorded. RESULTS: 5048 consecutivepatients underwent 6098 colonoscopies between 2009-2015. At least one polyp wasfound in 570 colonoscopies (9.3%) in 439 patients (8.7%). The mean age forpatients who had polyp(s) was 57 (range 16-98) and 62% of them were males.Abdominal pain was the most common (28%) indication for colonoscopies in patientwho had polyps in general, but the least common indication in cancer polyps cases.Altered bowel habits, bleeding per rectum and follow-up were the most commonindications for colonoscopies in cancer cases. Cancer was detected in 26 (4.3%) outof total 603 polyps. The rest of polyps were classical adenomas 260/603 (43.1%),serrated lesions 315/603 (52.2%) and others 2/603 (0.3%). Adenomas weresubdivided into tubular 172/260 (66.15%), tubule-villous 59/260 (22.7%) and villous29/260 (11.15%). Serrated lesions were subdivided into hyperplastic polyps 163/315(51.7%), mixed dysplastic/hyperplastic polyps 137/315 (43.5%), and others 15/315(4.8%). Polyps were predominantly left-sided colorectal (66.6%): descending colon(13.9%), sigmoid colon (17.3%), recto-sigmoid (15.6%) and rectum (19.8%). 12%of the polyps were synchronous. 43/53 (81%) of the high grade dysplasiaadenomatous polyps and 16/26 (65.4%) of the cancer polyps were in the left-sidedcolorectal area. About one third of all polyps, two thirds of the cancer polyps and twothirds of the high grade dysplastic adenomas were 1cm or greater in size. There wasno association between age or gender and the grade of dysplasia or cancer.CONCLUSION: Left sided colorectal polyps have higher risk of ‘cancer’ and ‘highgrade dysplastic adenomas’. Left-sided colorectal polyps must be treated moreseriously, especially the larger ones. 42

Name: Khalid Rashid Al-Alawi

Title: medical student

Primary Affiliation: Jordan University of Science & Technology

Address: Jordan University of Science & Technology P.O.Box

3030, Irbid 22110, Jordan


Other authors: Dr. Alqudha, M. Dr. Qandeel , H. Dr. Al-Manasra,

A.R. Dr. Obiedat, M. Dr. Elayyan, R. Dr. Al-Smadi, S.

Abstract title: Location and Histologic Features of Colonic Polyps:

Review of 6000 polyps colonoscopies and 600

polyps

Keywords: Colon cancer, colon polyps, polyps.

Abstract:

43

Name: Zaina Alazawi

Title: family medicine specialist

Primary Affiliation: Jordan ministry of health

Address: Aljubaiha, Amman tel # 0790858086


Other authors: Dr Ola Alqudah tel # 0797590304

[email protected]

Abstract title: Depression, Anxiety, and Sexual Dysfunction

among Jordanian Women with Type 2

Diabetes Mellitus

Keywords: sexual dysfunction; diabetes mellitus type 2;

depression; anxiety

INTRODUCTION/RATIONALE: Diabetes mellitus (DM) is one of the major chronicdiseases in Jordan and it was rank as a third leading cause of death, killed 1.7thousand persons in 2012. Diabetes mellitus type 2 (DMT2) usually associated withseveral complications and sexual dysfunction is one of these complications.Therefore, the aims of this study are: (1) to determine the prevalence of sexualdysfunction among Jordanian women with T2DM; (2) to examine the relationships offemale sexual dysfunction with demographic data, duration of the diabetes mellitus,type of treatment, HbA1c, BMI, and diabetes complications; and (3) to examine therelationships among depression, anxiety, and sexual dysfunction in Jordanian womenwith T2DM. METHODS: This study employed a cross-sectional, descriptive,correlational design. Inclusion criteria were women who are over the age of 18 yearsand less than 65 years, diagnosed with T2DM, married for at least 1 year, and had astable marital relationship. Women reported the presence of sexual disorders beforedeveloping DM or had a spouse with ongoing sexual disorders were excluded.Psychometrics tools were used to assess female sexual function, anxiety, anddepression. Physiological and biological measures were collected from the patient'smedical records. RESULTS: 107 women with DMT2 were subsequently recruited witha mean of age 52.46 years (± 8.38). The prevalence of female sexual dysfunctionwas 94.4%, and the lowest mean scores were reported for arousal domain (2.44 ±1.28), and orgasm domain (2.48 ± 1.34). This study found significant inverse

relationships between the female sexual function score and age (r = -0.340, p <0.01), DM duration (r = -0.211, p = 0.029), fasting blood sugar (r = -0.234, p =0.015), anxiety (r = -0.375, p < 0.01), and depression (r = -0.480, p < 0.01).CONCLUSION: female sexual dysfunction is widely prevalent in Jordanian womenwith T2DM (94.4%). There were significant correlations between anxiety, depressionand female sexual dysfunction among women with DMT2.

Abstract:

44

Aim: An increasing number of studies have focused on the quantification ofvisceral fat and subcutaneous fat in relation to some diseases. The aim of thisstudy was to check if there is a correlation with colorectal cancer staging (TNM).Methods: 31 patients who had abdominal CT scan as part of their assessment forcolorectal cancer were reviewed. NIH Image-J software of CT images was used toquantify adipose tissue and skeletal muscle cross-sectional areas (cm2). In ourstudy, subcutaneous fat, visceral fat and rectus muscle cross-sectional areas weremeasured at the level of L3 using standard Hounsfield unit ranges (adiposetissue: -190 to -30; skeletal muscle: -29 to +150). Two observers tookmeasurements separately to check reliability. TNM staging was obtained by aradiologist for each patient. Results: Patients’ mean age was 57 (range 38-75).45.2% of patients were females. Mean of Albumin was 41 (range 24-50). TNMranged from T1,N0,M0 to T4,N2,M1. Reliability analysis for CT-measuredparameters showed high ’Interclass Correlation Coefficient (ICC) betweenobservers for subcutaneous fat area (0.968), visceral fat area (0.997) and rectusabdominis muscle area (0.879). No correlation was found between (T, N or M)and (the CTscan measured areas of visceral fat, subcutaneous fat or rectusmuscles). No correlation was found between albumin versus either visceral fatarea (P=0.80), subcutaneous fat area (P=0.63) or rectus muscle area (P=0.56).There was a correlation between age and visceral fat area (P=0.054), but nocorrelation with subcutaneous fat area (P=0.40), rectus muscle area (P=0.30), oralbumin (P=0.11). Conclusions: Image-J software of CT images is reliable methodto quantify adipose and muscle areas. No correlation between colorectal cancerstage and the areas of fat and muscles. However, further studies with largersample size are required to ascertain the above results.

Name: Khalid Rashid Al-Alawi

Title: medical student

Primary Affiliation: Jordan University of Science & Technology

Address: Jordan University of Science & Technology

P.O.Box 3030, Irbid 22110, Jordan phone

number: +962777001410


Other authors: Qandeel , H Al Jaberi , T Al Aleet , w Al

Khateeb , A Gharaibeh , K Al manasra , A Al-

Zoubi , N

Abstract title: CT-MEASURED SUBCUTANEOUS AND

VISCERAL FAT IN PATIENT WITH

COLORECTAL CANCER

Keywords: colorectal cancer, cancer ,

Abstract:

45

Background and aim: to evaluate the impact of lower segment cesarean section(LSCS) on the maternal and fetal outcome of women with non-adherent placentaprevia (PP). Materials and Methods: This is a retrospective study of all womenwho delivered at our hospital by LSCS with or without non-adherent PP over aperiod of 10 years. Data were obtained through hospital registry and medicalrecords search. Results A total of 90 women with non-adherent placenta wereincluded, 54 women with no previous CS and 36 women with previous CS.Women with previous CS were significantly more likely to experience organ injury(p-value <0.005), transfusion of ≥ 4 units of PRBC (p-value = 0.034), transfusionof FFP (p-value = 0.034), and hysterectomy or other procedure ( B Lynch, Uterineartery ligation) use (p-value <0.005 Conclusion: There is a significant increase inthe incidence of maternal morbidities such as hysterectomy, blood transfusionand organ injury in patients with non-adherent PP with previous CS, with nodifference in perinatal outcome in the same group of patients.

Name: Areen Al Na’san

Title: 3rd year resedient

Primary Affiliation: KAUH \ OB\GYn department

Address: Ramthan Jordan


Other authors: Nail Obeidat

Abstract title: The impact of previous cesarean section on

the outcome in patients with non-adherent

placenta previa

Keywords: CS, Previa

Abstract:

46

Background Acute lower respiratory infection (ALRI) is a major cause of morbidityand mortality worldwide. Respiratory syncytial virus (RSV) is the most commonetiology of acute respiratory infection (ARI) in young children globally. Data aboutARI/ALRI and burden of the disease in developing countries are scarce. MethodsThis study is a prospective viral surveillance using real-time RT-PCR of children < 5years old who were admitted with fever and/or respiratory symptoms to two mainhospitals in Northern Jordan during winter period of 2016. We identified virusescausing ARI/ALRI in children, determined their demographic and clinicalcharacteristics and risk factors for increased length of hospital stay (LoS) and severepresentation. Results Patients hospitalized with ARI were 479. Their age mean(standard deviation (SD)) was 10.4(11.6) months. The mean (SD) LoS was 3.56(2.4) days. Of all patients, 15.0% were premature (specifically ≥ 29 to 36 weeks),20.5% had low birth weight, 4.4% had chronic lung disease and a chronic illnesspresented in 15.9%. RSV was the most common detected virus (34%). Compared tothose who were RSV-negative, RSV-positive children were significantly younger (P =0.030) and more likely to have chronic lung disease (7.4% vs. 2.8%; P = 0.022).Prematurity, presence of a chronic illness, SpO2 < 90% and atelectasis andconsolidation findings on chest x-ray were significantly associated with increasedmeans of LoS. Patients with a history of prematurity had higher odds of severepresentation (OR = 2.6; 95% confidence interval: 1.5, 4.7; P = 0.001). Patientsaged 6.1-12 months were significantly less likely to have severe disease compared topatients 6 months old or younger. Conclusions RSV is the most common cause ofARI-associated hospitalizations in Northern Jordan. This would help implementingfuture strategies for the RSV vaccine when it is available.

Name: Samah Awad

Title: assistant Professor


Address: JUST


Other authors:

Samah Awad , Yousef Khader , Moa’th Mansi ,

Dawood Yusef , Salah Alawadin, Walaa Qudah ,

Ruba Khasawneh

Abstract title:Viral Surveillance of Hospitalized Children with

Acute Respiratory Infection in Northern Jordan

Keywords:Acute respiratory infection, Children, Jordan,

Respiratory syncytial virus, Surveillance

Abstract:

47

Background : The ABO blood type system is expressed by antigen on both red bloodcells and normal tissue through the body. Overall, the association between bloodgroup and incidence of various types of cancers have been previously investigated.And because lung cancer became one of the major health issues and one of themost important leading causes of cancer-related deaths worldwide, its relation toABO/RH blood type is being investigated in many centers around the world, ourinstitution being one of them. Aims : The aim of the study was to determine whetherthere is an association of ABO/RH blood type With the development of lung cancer inthe Jordanian population. Methods : The study cohort consisted of 458 patients whowere diagnosed with a primary lung cancer at both King Abdullah University Hospital(KAUH) and Jordan university hospital in Jordan between 2005 and 2015. Twopopulations were designated as unmatched control groups. These comprised 3,847healthy blood donors and 654 accidental trauma patients (admitted to theDepartments of Neurosurgery and Orthopedics) at KAUH between 2014 and 2015.Control characteristics, including ABO blood group and Rh factor, were determinedfor both groups, using hospital records. Results : The adjusted effects of Rh, but notblood group, was a significant predictor of lung cancer diagnosis. Rh positivesubjects were significantly less likely to have lung cancer than Rh negative subjects.Conclusion : Blood group was not a significant predictor of lung cancer. Furtherstudies in this field are mandatory to understand the suggested relationship.

Name: Anas zaitoun

Title: Dr.

Primary Affiliation:jordan university of science and technology -

college of medicine



Other authors:

Nawwaf Alghamdi, Mohammad Alqudah , Mohammed Allouh ,Shadi Hamouri , NajlaDaoud, Tariq N Aladily, Khalid Kheirallah , Ismail Matalka

Abstract title: ABO Blood Groups and Lung Cancer

Keywords: Lung, Blood , Rh.

Abstract:

49

Background: The relationship between waterpipe smoking and eating habitsamong adolescents has not been investigated, thus the aim of the current studywas to compare eating habits among adolescent cigarette-only, waterpipe-only,dual smokers versus non-smokers. We hypothesize that adolescent smokerspractice unhealthy eating habits with worse habits among waterpipe smokers anddual smokers. Methods: Using a descriptive, cross-sectional design, self-reportingpatterns of waterpipe and cigarette smoking and eating habits were collected froma random representative sample of 1720 boys and girls in grades 7-10 in NorthernJordan. Results: A total of 6.9%, 23.2%, and 26.2% reported cigarette-only,waterpipe-only, and dual smoking, respectively. After covariating for gender, familyincome, and education level of the mother and father, subsequent post-hocANCOVA analyses revealed the following: weekly breakfast consumption wasgreater in non-smokers than waterpipe-only smokers (p=0.04) and dual smokers(p<0.0001). Soda consumption frequency was lower in non-smokers versuswaterpipe-only (p=0.004) and dual smokers (p=0.0001). Vegetable consumptionwas less in waterpipe-only (p=0.026) and dual (p=0.013) smokers versus non-smokers. Consumption of energy drinks was the highest among dual smokersversus non-smokers (p<0.0001), cigarette-only (p<=0.01), and waterpipe-only(p<0.0001) smokers. Conclusions: Overall, both waterpipe and dual smoking areassociated with several unhealthy eating habits in adolescents. Given the growingepidemics of tobacco smoking in the Eastern Mediterranean Region, especiallyadolescent waterpipe smoking, and its association with unhealthy eating habits,public health actions are urgently needed.

Name: Nihaya Al-sheyab

Title: Dr

Primary Affiliation: Associate Professor

Address:Jordan University of Science and

Technology


Other authors: Prof/Dr. Mahmoud A Alomari

Abstract title:Unhealthy eating habits among

adolescent waterpipe smokers

Keywords:waterpipe smoking, adolescents,

eating habits

Abstract:

50

The prevalence of asthma in Jordanian adolescents is high (12.3%) indicating asignificant increase in asthma and asthma symptoms in this population over adecade. While cigarette smoking is a major health issue, waterpipe (WP) use is agrowing concern as well as these two tobacco products are instantly related.Adolescents with asthma often have high rates of smoking. The current data werederived from the “Irbid Tobacco Risk in Youth (Irbid-TRY)”; a prospective,longitudinal study designed to assess the health risks of tobacco consumption. Thecurrent investigation used a descriptive, cross-sectional design to examine theassociations of asthma and smoking among the adolescents in the Irbid-TRY study.Overall, our findings show a positive association between different types andfrequency of tobacco smoking and the rate of asthma and wheezing amongadolescents. In specific, current (past month) tobacco smoking more than doubledthe odds of recent (past 12 months) wheezing. This occurred for all sub-groups oftobacco smokers, including those who smoked only cigarettes (i.e, no waterpipe) inthe past month, those who smoked only waterpipe (i.e, no cigarettes) in the pastmonth, those who smoked both cigarettes and waterpipe (dual) in the past month,and those who had ever smoked either cigarettes or waterpipe but did not smokein the past month. The current study also examined the “dose” effects throughcalculating the odds of wheezing as a function of frequency of use of cigarettes,waterpipe, and dual tobacco smoking. Our findings generally showed increasedodds ratios for students who smoked most frequently. Our findings add to agrowing body of research indicating that waterpipe smoking, alone and incombination with cigarette smoking (dual smoking), increases the risk ofpulmonary disease. Several cross-sectional and case-control studies show thatwaterpipe use is associated with increased risk of COPD.

Name:0 Nihaya Al-sheyab

Title: Dr

Primary Affiliation: Associate Professor



Other authors:

Mahmoud A Alomari, PhD1 Weiyu Chen, MPH2

Kenneth D Ward, PhD2 1Jordan University of

Science and Technology 2University of Memphis

Abstract title:

Associations of cigarette and waterpipe smoking

with asthma and wheezing among Jordanian

adolescents

Keywords: waterpipe smoking, cigarettes, asthma, wheezing

Jordan University of Science and TechnologyFaculty of Medicine

جامعة العلوم والتكنولوجيا األردنيةكليــــة الطب

Speakers - Jordan University of Science and Technology · Dr. Mahmoud Alfaqih ... 1:50-2:05 Advances in the treatment of metastatic lung cancer Dr. Osama Alshari ... Postdoctoral

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