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A review of NPL audit Russell Thomas Radiation Dosimetry Group, National Physical Laboratory
32

Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Jul 11, 2018

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Page 1: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

A review of NPL audit

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

Page 2: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

A review of NPL audit

or

What are we actually trying to

achieve?

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

Page 3: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Monday, 13 January 2014

3

History

• 4th January 1994

• 1994 commenced IPEM/NPL

Photon MV reference dosimetry audits

• Linking the eight regional audit groups

• Later expanded into kV Photons and

Electrons (1996 & 2003)

• Support for development of Alanine based

services for Gamma Knife, Tomotherapy

Cyber knife, Protons and the National IMRT

audit & NRRA

Page 4: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Basic structure for all reference dosimetry audits:

• Beam quality

• Machine output

• Field instrument calibration

+ specific areas such as ion recombination

+ individual areas of concern

Page 5: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

The easy “also checked”

• Temperature

• Pressure

• Laser Alignment

• SSD/Front pointer agreement

• Storage conditions of equipment

• Certification/calibration/ traceability

• Not Paper trails (if it’s written down and you

do it that’s a pass even if it’s not best

practice)

Monday, 13 January 2014

5

Page 6: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Audit is not just about getting two numbers

to agree within a tolerance.

• My Gray = Your Gray, PASSED

on to the next department…..

• My Gray = Your Gray, PASSED

on to the next department…..

• My Gray = Your Gray, PASSED

on to the next department…..

Monday, 13 January 2014

6

Page 7: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

It’s about the touchy feely

stuff too….

7

Page 8: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

It’s about the touchy feely

stuff too….

8

Page 9: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Auditing – a bit like

cracking a safe really!

Monday, 13 January 2014

9

Page 10: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

MV photon audit

set up

Page 11: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Monday, 13 January 2014

11

0.9800

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

0 10 20 30 40 50 60 70

Rati

o N

PL

/Ho

st

Audit number

Beam quality index (TPR)

NPL/Host 0.998 std dev 0.5%

Page 12: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

MV photon field

instrument calibration

0.9800

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

1.0200

0 10 20 30 40 50 60 70

Ra

tio

NP

L/H

os

t

Audit number

Field Instrument calibration

NPL/Host

1.001

std dev 0.7%

Page 13: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Monday, 13 January 2014

13

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

1.0200

1.0250

0 10 20 30 40 50 60 70

Ra

tio

NP

L/H

os

t

Audit number

Machine output (cGy/MU)

NPL/Host 1.003 std dev 0.7%

Nisbet/Host 1.003 std dev 1.0%

Thwaites/Host 1.003 std dev 1.5%

Page 14: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Electron 2003 C of P

Depth dose measurements in water

Page 15: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Electron 2003 C of P

measurements in solid water

Page 16: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Electrons 2003

C of P

0.994

0.996

0.998

1

1.002

1.004

1.006

1.008

1.01

1.012

1.014

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Machine output

NPL/Host 1.003 std dev 0.3%

Nisbet/Host 0.994 std dev 1.8%

NPL/Host 1.003 std dev 0.4%

0.996

0.998

1

1.002

1.004

1.006

1.008

1.01

1.012

1.014

0 1 2 3 4 5 6 7 8

Rati

o N

PL

/Ho

st

Audit number

Field instrument

Page 17: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

kV set up for HVL

measurements

Page 18: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

kV audit results

0.85

0.9

0.95

1

1.05

1.1

1.15

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Beam Quality

NPL/Host

1.018

std dev 4.7%

Page 19: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

kV audit results

0.96

0.97

0.98

0.99

1

1.01

1.02

1.03

1.04

1.05

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Machine output

Machine output

expected

NPL/Host 1.002 std dev 0.8% NPL/Host 1.002 std dev 0.6%

0.96

0.97

0.98

0.99

1

1.01

1.02

1.03

1.04

1.05

0 1 2 3 4 5 6 7 8

Rati

o N

PL

/Ho

st

Audit number

Field Instrument

(1.5%)

Page 20: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

A review of NPL audit

or

What are we actually

trying to achieve?

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

Page 21: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

NPL is usually about uncertainty to 1 part in

so many million

“NPL's atomic clock revealed to

be the world's most accurate”

"Together with other improvements of the caesium

fountain, these models and numerical calculations

have improved the accuracy of the UK's caesium

fountain clock, NPL-CsF2, by reducing the

uncertainty to 2.3 × 10-16 - the lowest value for any

primary national standard so far."

Monday, 13 January 2014

21

Page 22: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

• ICRU 24 - Dose delivery to the primary

target should be within +/- 5% of the

prescribed value (some literature is quoting

that this should be within +/- 2%)

Monday, 13 January 2014

22

Page 23: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

• ICRU 24 - Dose delivery to the primary

target should be within +/- 5% of the

prescribed value (some literature is quoting

that this should be within +/- 2%)

• Uncertainty on the NPL calibration of the

Secondary Standard 2611 chamber is

+/-1.5%

Monday, 13 January 2014

23

Page 24: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

UK Codes of Practice Monday, 13 January 2014

24

Page 25: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

What are WE trying to achieve? Is it :-

• Just not getting caught with our pants down

• Delivering a “legal” dose

• Are we fulfilling a tick box exercise? ie

traceability and audit – done!

Monday, 13 January 2014

25

Page 26: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

What are WE trying to achieve? Is it :-

• Just not getting caught with our pants down

• Delivering a “legal” dose

• Are we fulfilling a tick box exercise? ie

traceability and audit – done!

or

• Are we aiming for best practice and treatment

• As tight a consistency of dose delivered to

individuals across a patient population

Monday, 13 January 2014

26

Page 27: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

A statement made to me by a clinical

oncologist -

“Accurate dosimetry is not that important”

Monday, 13 January 2014

27

Page 28: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

A statement made to me by a clinical

oncologist -

“Accurate dosimetry is not that important”

….but if you can’t get your reference

dosimetry right, no complex treatment you

deliver will be “correct”.

Monday, 13 January 2014

28

Page 29: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

• In my view audit, and indeed reference

dosimetry audit, is a crucial component in

the provision of the complex radiotherapy

that is, and will become, available with

current and future technology.

Monday, 13 January 2014

29

Page 30: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

But there are issues:-

• Hidden costs

Monday, 13 January 2014

30

Page 31: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

But there are issues:-

• Hidden costs

• Pressure on staff time

• People feel over audited

• Value and benefit

• Regulation

• Lack of senior management understanding

Monday, 13 January 2014

31

Page 32: Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

Monday, 13 January 2014

32

Thank you, questions?