Solutions for CRRT Comparisons March 2009 Home: Critical Care : Products : Fluids NxStage prepackaged fluids for acute renal care NxStage provides a full range of easy-to-use, convenient and economical sterile dialysate fluids that simplify the delivery of intensive care dialysis. NxStage PureFlow™ prepackaged solutions offer significant advantages: They are available with bicarbonate or lactate buffers, giving you treatment options. NxStage PureFlow Solutions ensure fluid quality, with potential clinical benefits. They meet or exceed AAMI, USP, and European Pharmacopoeia standards. Products are terminally sterilized and pyrogen-free (< 0.25 EU/mL). They eliminate the need to install large, complex water purification systems. They allow for simple dosing and usage, reducing workload on busy ICU staff. • Convenient 5-liter bags minimize interventions. Your choice of solution buffer: Bicarbonate—The body’s natural buffer; may be suitable for patients with lactic acidosis and/or liver failure. The two-compartment bag with unique peel-seam interface simplifies preparation and mixing. Lactate—Simplest, most economical solution; no mixing required. Effectiveness for most patients is well-supported in clinical literature. NxStage PureFlow Solutions for use in acute hemodialysis with the NxStage System One include: Lactate Buffer Bicarbonate Buffer Constituent (mEq/L) RFP-204 RFP-205 RFP-207 RFP-400 RFP-401 RFP-402 RFP-453 RFP-454 Lactate 40 35 45 0 0 0 0 0 Bicarbonate 0 0 0 35 35 35 25 25 Potassium 1 3 1 2 4 0 2 4 Sodium 140 140 140 140 140 140 130 130 Calcium 3 3 3 3 3 3 0 0 Magnesium 1 1 1 1 1 1 1.5 1.5 Chloride 105 112 100 111 113 109 108.5 110.5 Glucose (mg/dL) 100 100 100 100 100 100 100 100 NxStage PureFlow Solutions are indicated for use with renal replacement systems that utilize sterile premixed dialysate. They are not indicated for direct infusion.
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Solutions for CRRT Comparisons March 2009
Home: Critical Care: Products: Fluids
NxStage prepackaged fluids for acute renal care
NxStage provides a full range of easy-to-use, convenient and economical sterile dialysate fluids that
simplify the delivery of intensive care dialysis. NxStage PureFlow™ prepackaged solutions offer
significant advantages:
They are available with bicarbonate or lactate buffers, giving you treatment options.
NxStage PureFlow Solutions ensure fluid quality, with potential clinical benefits. They meet
or exceed AAMI, USP, and European Pharmacopoeia standards. Products are terminally sterilized
and pyrogen-free (< 0.25 EU/mL).
They eliminate the need to install large, complex water purification systems.
They allow for simple dosing and usage, reducing workload on busy ICU staff.
• Convenient 5-liter bags minimize interventions.
Your choice of solution buffer:
Bicarbonate—The body’s natural buffer; may be suitable for patients
with lactic acidosis and/or liver failure. The two-compartment bag with
unique peel-seam interface simplifies preparation and mixing.
Lactate—Simplest, most economical solution; no mixing required.
Effectiveness for most patients is well-supported in clinical literature.
NxStage PureFlow Solutions for use in acute hemodialysis with the
PrismaSate® DialysateEasy-to-use dialysate formulas specifically designed for critical care.
PrismaSate® dialysate offers six formulas specifically designed forContinuous Renal Replacement Therapy (CRRT). These dialysateformulas save time and expense and provide unmatched prescriptionflexibility. PrismaSate features:
• Each 5-liter, two-compartment bag contains electrolytes andbicarbonate in easy-to-mix solutions that reduce pharmancy laborand the potential for human error
• No additional syringes, lines or sterile water needed
• Enables fast and easy bedside preparation and reduced bagchanges
• Includes bar code label to verify that the right formula isbeing administered to the right patient
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PrismaSol Replacement SolutionWe've done the compounding so you don't have to.
PrismaSol replacement solutions, like PrismaSate® dialysate, is commerciallyproduced. This feature, when compared with manual compounding and othersolutions that require mixing, assists in the reduction of the complexity and the riskof error.
• Sterile bag enables fluid to remain stable for 24 hours after the protectiveover-wrap is removed and has a 12-month shelf life, ensuring cost-effectivenessand easy storage
• Pre-mixed 5-liter bag reduces bag changes and eliminates the need forcompounding
• Fast and easy bedside preparation, read-to-mix within the confines of a 2-compartment, 5-liter bag
• Provides both options of a spike port and luer lock port for connecting thereplacement fluid line
PrismaSolSterile Hemofiltration and Hemodiafiltration solution
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins. This solution is used in Continuous RenalReplacement Therapies (CRRT) as a replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol is packaged in a two-compartment bag. The small compartment A contains electrolytes and the largecompartment B contains buffer. The final reconstituted solution (5000 mL) is obtained after breaking the red frangible pinbetween compartments A and B and mixing both solutions. The compositions of the solution before and after reconstitutionare described in the following tables.
PrismaSol Replacement SolutionWe've done the compounding so you don't have to.
PrismaSol replacement solutions, like PrismaSate® dialysate, is commerciallyproduced. This feature, when compared with manual compounding and othersolutions that require mixing, assists in the reduction of the complexity and the riskof error.
• Sterile bag enables fluid to remain stable for 24 hours after the protectiveover-wrap is removed and has a 12-month shelf life, ensuring cost-effectivenessand easy storage
• Pre-mixed 5-liter bag reduces bag changes and eliminates the need forcompounding
• Fast and easy bedside preparation, read-to-mix within the confines of a 2-compartment, 5-liter bag
• Provides both options of a spike port and luer lock port for connecting thereplacement fluid line
PrismaSolSterile Hemofiltration and Hemodiafiltration solution
PrismaSol solution is a clear, sterile solution free of bacterial endotoxins. This solution is used in Continuous RenalReplacement Therapies (CRRT) as a replacement solution in hemofiltration and hemodiafiltration.
It contains no bacteriostatic or antimicrobial agents.
PrismaSol is packaged in a two-compartment bag. The small compartment A contains electrolytes and the largecompartment B contains buffer. The final reconstituted solution (5000 mL) is obtained after breaking the red frangible pinbetween compartments A and B and mixing both solutions. The compositions of the solution before and after reconstitutionare described in the following tables.