Journal of Sol-Gel Science and Technology https://doi.org/10.1007/s10971-020-05245-8 REVIEW PAPER: FUNDAMENTALS OF SOL – GEL AND HYBRID MATERIALS PROCESSING Sol–gel synthesis of calcium phosphate-based biomaterials—A review of environmentally benign, simple, and effective synthesis routes Kunio Ishikawa 1 ● Edita Garskaite 2,3 ● Aivaras Kareiva 3 Received: 3 November 2019 / Accepted: 31 January 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020 Abstract In this review article the available results about application of sol–gel synthesis method for the preparation of different calcium phosphates and composite materials are summarized. The attention is paid to calcium phosphate-containing compounds which show the biological properties and could be used as potential phosphate bioceramics in medicine. It was demonstrated that the sol–gel synthesis method is a powerful tool for the synthesis of calcium hydroxyapatite and other phosphates, and different calcium phosphate-based composites at mild synthetic conditions resulted in high reproducibility, high phase purity, and desired morphology. Thus, the sol–gel synthesis method enables the researchers to develop biomaterials with superior features in terms of biomedical applications. Graphical Abstract For the synthesis of calcium phosphate biomaterials an effective sol–gel chemistry approaches have been developed. KI, EG, and AK. “Sol–gel synthesis of calcium phosphate-based biomaterials—A review of environmentally benign, simple, and effective synthesis routes”. Keywords Calcium hydroxyapatite ● Calcium phosphates ● Glasses ● Composites ● Sol–gel synthesis * Aivaras Kareiva [email protected] 1 Department of Biomaterials, Faculty of Dental Science, Kyushu University, Maidashi, Higashi-Ku, Fukuoka, Japan 2 Wood Science and Engineering, Department of Engineering Sciences and Mathematics, Luleå University of Technology, Forskargatan 1, SE-931 87 Skellefteå, Sweden 3 Institute of Chemistry, Vilnius University, Naugarduko 24, LT-03225 Vilnius, Lithuania 1234567890();,: 1234567890();,:
Sol–gel synthesis of calcium phosphate-based biomaterials—A review of environmentally benign, simple, and effective synthesis routes
Jul 18, 2023
In this review article the available results about application of sol–gel synthesis method for the preparation of different
calcium phosphates and composite materials are summarized. The attention is paid to calcium phosphate-containing
compounds which show the biological properties and could be used as potential phosphate bioceramics in medicine. It was
demonstrated that the sol–gel synthesis method is a powerful tool for the synthesis of calcium hydroxyapatite and other
phosphates, and different calcium phosphate-based composites at mild synthetic conditions resulted in high reproducibility,
high phase purity, and desired morphology. Thus, the sol–gel synthesis method enables the researchers to develop
biomaterials with superior features in terms of biomedical applications.
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In this review article the available results about application of sol–gel synthesis method for the preparation of different calcium phosphates and composite materials are summarized.
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