SOCIETY FOR ENDOCRINOLOGY BES 2009

www.endocrinology.org/meetings

FREE REGISTRATION, ACCOMMODATION AND TRAVEL FOR TRAINEES – SEE PAGE 8 FOR FURTHER DETAILS.

SOCIETY FOR ENDOCRINOLOGY BES 2009

PRELIMINARY PROGRAMME

16-19 March 2009 Harrogate International Centre

Abstract deadline: 15 November 2008

1SOCIETY FOR ENDOCRINOLOGY BES 2009

SOCIETY FOR ENDOCRINOLOGY BES 200916-19 March 2009 Harrogate International CentreThe Society for Endocrinology would like to thank their Corporate Members for their generous support.

PLATINUM MEMBERS BioScientifica Ltd Bayer Schering Pharma Ipsen Ltd Pfizer Ltd

GOLD MEMBERS AstraZeneca plc Ferring Pharmaceuticals Ltd Merck Serono Novartis Pharmaceuticals UK Ltd Novo Nordisk Ltd

SILVER MEMBERS Almirall Ltd Eli Lilly & Co Ltd Genzyme Therapeutics Ltd Nycomed UK Ltd ProStrakan Sandoz Ltd

CONFERENCE SECRETARIAT Society for Endocrinology 22 Apex Court Woodlands Bradley Stoke Bristol BS32 4JT, UK Tel: +44 (0)1454 642210 Fax: +44 (0)1454 642222 Email: [email protected] Website: www.endocrinology.org The Society for Endocrinology Company Limited by Guarantee Registered in England No 349408 Registered office as shown above Registered Charity No 266813

We are delighted to provide you with preliminary details of the Society for Endocrinology BES 2009 meeting, taking place once again in the spa town of Harrogate on 16-19 March 2009. We are looking forward to building upon the success of our 2008 meeting and have planned an exciting scientific programme. This annual meeting brings together the best of basic science, translational research, clinical investigation and clinical practice.

The meeting will encompass nine plenary lectures, six of which being Society medal lectures. There will be ten symposia including the Young Endocrinologists’ symposium. Other sessions include Clinical Management Workshops, Meet the Expert sessions, Nurse sessions and a Clinical Debate.

The meeting will feature both oral communications and poster presentations. There will be many prizes available for high scoring presentations by Young Endocrinologists.

Harrogate is a picturesque town located in the heart of the Yorkshire Dales. This pretty market town is filled with boutiques, antique shops and fantastic accommodation and the best Tea Rooms in the UK, Betty’s! The conference facilities are excellent, the Harrogate International Centre being the second largest venue outside of London.

The event will host a varied social programme which will include all the favourites such as the Welcome Reception at the Majestic Hotel and the Young Endocrinologists’ quiz at the HIC. An informal buffet will be held on the Tuesday evening at the Majestic Hotel. Great food and lively entertainment will help to make this an evening to remember.

Abstracts can be submitted online at www.endocrinology.org/meetings/2009/sfebes2009/abstracts.html and the abstract deadline is 15 November 2008. Registrations can also be submitted online. All meeting information is available at www.endocrinology.org/meetings/2009/sfebes2009/.

We look forward to seeing you in Harrogate.

2009 WELCOME


David RayProgramme Secretary, Society for Endocrinology

Steve BallProgramme Co-ordinator, Society for Endocrinology BES 2009

09:00 – 10:45 REGISTRATION

10:45 – 12:15 PCOS SPECIAL INTEREST GROUP SATELLITE Convened by: S Atkin (Hull) & H Randeva (Warwick)

STEROIDS SPECIAL INTEREST GROUP SATELLITE Convened by: M Wallace (Glasgow) & W Arlt (Birmingham)

PITUITARY SPECIAL INTEREST GROUP SATELLITE Convened by: R Murray (Leeds), R Fowkes (London) & J Ham (Cardiff)

12:15 – 13:00 LUNCH

13:00 – 15:00 Symposium 1: FINDING THE RIGHT BALANCE OF DIETARY

AND METABOLIC INFLUENCES IN FETAL AND ADULT LIFE Chairs: M Symonds (Nottingham) & B Kola (London)

Glucocorticoids, chronic stress, and obesity M Dallman (San Francisco, USA) Transgenerational programming of the

glucocorticoid axis and maternal stress A Drake (Edinburgh)

Maternal undernutrition and endocrine development M Hanson (Southampton)

The fetal cost of maternal cafeteria diets N Stickland (London)

13:00 – 15:00 Clinical Management Workshop 1: MEASURING HORMONES: WHAT DOES

YOUR RESULT MEAN? Chairs: S Ball (Newcastle-upon-Tyne) & E Murphy (London)

What service does the laboratory provide? J Barth (Leeds) Is what is normal for me normal for you? G Wieringa (Manchester) What new tests are on the horizon? G Beastall (Glasgow) Interpreting results: a clinician’s perspective S Shalet (Manchester)

13:00 – 15:00 Applied Physiology Workshop: METABOLIC PHENOTYPING IN HUMAN ENDOCRINE DISORDERS Chairs: M Gurnell (Cambridge) & TBC

Assessment of calorie intake and feeding behaviour R Batterham (London) Measurement of energy expenditure and body composition TBC The hyperinsulinaemic euglycaemic clamp and stable isotope methodology for in-vivo physiological studies H Simpson (Cambridge) Magnetic Resonance Spectroscopy – a window in to carbohydrate and lipid metabolism D Savage (Cambridge)

15:00 – 15:30 COFFEE

15:30 – 17:30 Symposium 2: CALCIUM CONUNDRUMS: TOO HIGH,

TOO LOW AND WHAT TO DO Chairs: J Walsh (Sheffield) & R Lindsay (New York, USA)

Management of severe hypercalcaemia D Hosking (Nottingham) Diagnosis and management of

post-operative hypocalcaemia following (para) thyroidectomy N Gittoes (Birmingham)

Familial benign hypocalciuric hypercalcaemia – an update K Brixen (Odense, Denmark)

Mild hyperparathyroidism: to treat or not to treat, that is the question R Mihai (Oxford)

15:30 – 17:30 ORAL COMMUNICATIONS 1


17:30 – 17:45 TEA

17:45 – 18:25 YOUNG ENDOCRINOLOGISTS PRIzE LECTURES Chairs: P Trainer (Manchester) & M Korbonits (London)

18:25 – 18:55 SOCIETY FOR ENDOCRINOLOGY JUBILEE MEDAL LECTURE Chair: D Ray (Manchester)

Per ardua ad pituita - more than just phlegm J Wass (Oxford)

19:00 WELCOME RECEPTION

19:45 YOUNG ENDOCRINOLOGISTS’ QUIz NIGHT

MONDAY 16 MARCH 2009

3SOCIETY FOR ENDOCRINOLOGY BES 2009

SCIENTIFIC PROGRAMME

07:15 – 08:00 Clinical Expert 1: THYROID EYE DISEASE

(CLINICAL EVALUATION AND CLASSIFICATION – EUGOGO) Chair: M Vanderpump (London)

P Perros (Newcastle-upon-Tyne)

07:15 – 08:00 Clinical Expert 2: DELAYED PUBERTY Chair: J Wales (Sheffield) J Kirk (Birmingham) 08:15 – 10:15 Symposium 3: WHAT’S WNT? A NOVEL SIGNALLING

PATHWAY IN ENDOCRINOLOGY Chairs: M Dattani (London) & R Fowkes (London)

Wnt signalling and its role in adrenal cancer G Hammer (Ann Arbor, USA) Targeting mediators of Wnt signalling

by GnRH A Pawson (Edinburgh)

Defects in Wnt signalling in hyperparathyroidism G Westin (Uppsala, Sweden)

Paracrine signalling in the ovary: the role of Wnt D Boerboom (Québec, Canada)


08:15 – 10:15 Clinical Management Workshop 2: IMPROVING MORTALITY AND

MORBIDITY IN PITUITARY DISEASE Chairs: J Ahlquist (Southend) & V Moyes (London)

Mortality in patients with pituitary disease J Newell-Price (Sheffield) Does hormone replacement normalise

life expectancy? W Drake (London)

Why craniopharyngioma remains a condition with a high mortality and morbidity N Karavitaki (Oxford)

Adverse outcomes following pituitary radiotherapy J Ayuk (Birmingham)

10:15 – 10:45 COFFEE

10:45 – 11:25 SOCIETY FOR ENDOCRINOLOGY DALE MEDAL LECTURE Chair: J Wass (Oxford) Healthspan: how far can it be extended into aging? M Thorner (Charlottesville, USA)

11:25 – 11:55 SOCIETY FOR ENDOCRINOLOGY TRANSATLANTIC MEDAL LECTURE Chair: TBC Estrogen action: two decades

of humbling predictions L Jameson (Chicago, USA)

12:00 – 13:30 LUNCH & POSTERS

13:30 – 15:30 Symposium 4: WHAT IS THE TSH SET POINT?

DOES IT MATTER? Chairs: G Williams (London) & M Gurnell (Cambridge)

Physiological determination of HPT axis R Weiss (Chicago, USA)

Genetic determinants of HPT axis set point R Peeters (Rotterdam, Netherlands) Abnormalities of HPT axis – lessons

from paediatric endocrinology T Cheetham (Newcastle-upon-Tyne)

Pathological consequences of altered HPT axis set-point; sub-clinical thyroid disease?... S Pearce (Newcastle-upon-Tyne)


13:30 – 15:30 Young Endocrinologists’ Symposium: THE ‘HOW-TO’ GUIDE ON

SCIENTIFIC COMMUNICATION Chairs: K Jonas (London) & K Forbes (Manchester)

How to write a scientific paper J Davis (Manchester) Conference presentations –

how to engage your audience R Batterham (London)

Poster presentations – from poster layout to data presentation G Lavery (Birmingham)

Scientific networking – how to make the most of networking opportunities S Hillier (Edinburgh)

15:30 – 16:00 TEA

16:00 – 17:00 Clinical Debate: THIS HOUSE BELIEVES THAT RADIOACTIVE

IODINE IS THE FIRST LINE OF TREATMENT FOR GRAVES’ DISEASE Chair: J Franklyn (Birmingham)

For: K Meeran (London) Against: W Wiersinga

(Amsterdam, Netherlands)

16:00 – 17:00 Clinical Expert 1: Repeat THYROID EYE DISEASE

(CLINICAL EVALUATION AND CLASSIFICATION – EUGOGO) Chair: M Vanderpump (London)

P Perros (Newcastle-upon-Tyne)

17:00 – 18:00 Clinical Expert 2: Repeat DELAYED PUBERTY Chair: J Wales (Sheffield) J Kirk (Birmingham)


16:00 – 18:00 Symposium 5: THE ENDOPLASMIC RETICULUM

– AN IMPORTANT LINk BETWEEN INFLAMMATION, STRESS AND DIABETES Chairs: K Chapman (Edinburgh) & G Lavery (Birmingham)

Endoplasmic reticulum: inflammation, obesity and diabetes R Kaufman (Ann Arbor, USA)

Regulation of hepatic lipid metabolism: interplay between insulin and the endoplasmic reticulum P Ferre (Paris, France)

The endoplasmic reticulum as a metabolic compartment G Banhegyi (Budapest, Hungary)

Glucose sensing in the endoplasmic reticulum: maintaining the cellular environment G Lavery (Birmingham)

19:30 CONFERENCE DINNER

SCIENTIFIC PROGRAMMETUESDAY 17 MARCH 2009

4 SOCIETY FOR ENDOCRINOLOGY BES 2009

07:15 – 08:00 Clinical Expert 3: TURNER SYNDROME – HOW TO

SMOOTH THE TRANSITION BETWEEN PAEDIATRIC AND ADULT CLINIC Generously supported by Ipsen Ltd Chair: G Conway (London)

M Davies (London)

07:15 – 08:00 Clinical Expert 4: VITAMIN D DEFICIENCY, DIAGNOSIS

AND MANAGEMENT Chair: P Selby (Manchester)

Z Mughal (Manchester)

08:10 – 08:55 SOCIETY FOR ENDOCRINOLOGY ANNUAL GENERAL MEETING

09:00 – 11:00 Symposium 6: POLYCYSTIC OVARIAN SYNDROME

(PCOS): WHEN DOES IT START, WHY AND WHAT TO DO ABOUT IT? Chairs: C Duncan (Edinburgh) & T Barber (Oxford)

Searching for candidate genes: what are the players? S Franks (London)

Evolution of obesity and insulin resistance: relevance to PCOS T Barrett (Birmingham)

The teenager with polycystic ovarian syndrome C Kelnar (Edinburgh)

Metformin – a storm with few good data R Legro (Hershey, USA)

09:00 – 11:00 Symposium 7: PHOSPHOINOSITIDE 3-kINASE (PI3k)

SIGNALLING IN HEALTH AND DISEASE: AN OLD SYSTEM WITH NEW POTENTIAL Chairs: R Abayasekara (London) & TBC

Signalling from cell surface receptors: molecular mechanisms and physiological significance of the phosphoinositide 3-kinase signalling system P Hawkins (Cambridge)

Disordered phosphoinositide signalling and the basis of tumour formation N Leslie (Dundee)

Insulin: role of PI3 kinase signalling in growth and metabolism – lessons from flies and mice M Birnbaum (Philadelphia, USA)

PI3 kinase inhibitors: fantasy or reality P Workman (London)

09:00 – 11:00 Nurses’ session 1: Chairs: M Carson (Edinburgh) & TBC HRT H Buckler (Manchester) HRT case TBC Recent advances in male hypogonadism F Wu (Manchester) Hypogonadism case D Wright (Bradford)11:00 – 11:25 COFFEE

11:25 – 11:30 EUROPEAN SOCIETY OF ENDOCRINOLOGY TALk E Nieschlag (Münster, Germany)

11:30 – 12:05 SOCIETY FOR ENDOCRINOLOGY EUROPEAN MEDAL LECTURE Chair: J Wass (Oxford)

Early stages of thyroid autoimmunity W Wiersinga (Amsterdam, Netherlands)

12:05 – 12:40 SOCIETY FOR ENDOCRINOLOGY INTERNATIONAL MEDAL LECTURE Chair: J Buckingham (London)

Hormones and behaviour: new insights from GFP molecular imaging and neuroanatomy

M Kawata (Kyoto, Japan)

12:40 – 14:15 LUNCH & POSTERS

14:15 – 16:15 Symposium 8: NOVEL ASPECTS OF BONE PHYSIOLOGY IN

RELATION TO OSTEOPOROSIS TREATMENT Chairs: P Selby (Manchester) & K Javaid (Oxford)

New tools for the study of bone-active drugs R Eastell (Sheffield) Bone signalling pathways – their importance

in the treatment of osteoporosis G Williams (London)

Anabolic treatments in osteoporosis R Lindsay (New York, USA) Bisphosphanates uses and abuses (including

young people and duration of therapy) A McLellan (Glasgow)

14:15 – 16:15 Symposium 9: kISSPEPTIN A NOVEL REGULATOR

OF PUBERTY AND FERTILITY Chairs: L Jameson (Chicago, USA) & K Murphy (London)

Kisspeptin signalling and fertility W Colledge (Cambridge) Role of kisspeptin in the metabolic

regulation of fertility M Tena-Sempere (Cordoba, Spain)

Human kisspeptin receptor mutations and puberty S Seminara (Boston, USA)

What does kisspeptin do in humans? W Dhillo (London)

14:15 – 16:15 Nurses’ session 2: Chair: D Wright (Bradford) & TBC Thyroid replacement C Dayan (Bristol) Thyroid case TBC Pregnancy/paediatric/adolescence TBC Case presentation TBC

16:15 – 16:45 TEA

16:45 – 16:55 AWARDS CEREMONY

16:55 – 17:30 BRITISH THYROID ASSOCIATION PITT-RIVERS LECTURE Chair: J Franklyn (Birmingham)

A 30-year perspective on radioiodine therapy for nontoxic goitre. From non-acceptance to implementation of rhTSH-augmented therapy

L Hegedüs (Odense, Denmark)

17:30 – 18:05 CLINICAL ENDOCRINOLOGY VISITING PROFESSOR LECTURE Chair: A Weetman (Sheffield) What have we learned about the management

of patients with prolactinomas? M Molitch (Chicago, USA)

18:05 – 19:35 ANDROLOGY SPECIAL INTEREST GROUP SATELLITE Convened by: H Jones (Barnsley,Sheffield) & F Wu (Manchester)

18:05 – 19:35 NOVO NORDISk SATELLITE

WEDNESDAY 18 MARCH 2009

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SCIENTIFIC PROGRAMME


07:15 – 08:00 Clinical Expert 5: DIFFERENTIAL DIAGNOSIS OF CUSHING’S Chair: K Meeran (London) A Grossman (London)

07:15 – 08:00 Clinical Expert 6:

THE TIRED PATIENT Chair: S Aylwin (London) J Miell (London)

08:15 – 08:50 SOCIETY FOR ENDOCRINOLOGY MEDAL LECTURE Chair: D Ray (Manchester) New genes, new diabetes and new treatments A Hattersley (Exeter)

08:55 – 09:30 CLINICAL ENDOCRINOLOGY TRUST LECTURE Chair: L Rees (London) The metabolic consequences

of pituitary insufficiency D Johnston (London)

09:30 – 10:00 COFFEE

10:00 – 12:00 Clinical Management Workshop 3: ENDOCRINE CONSEQUENCES

OF CANCER TREATMENT Chairs: R Ross (Sheffield) & H Spoudeas (London)

Survivorship following cancer – an overview M Hawkins (Birmingham)

Gonadal function and fertility potential R Anderson (Edinburgh) Pituitary and thyroid dysfunction,

who gets it, when to test and where? H Gleeson (Manchester)

Survivorship and models of care for the endocrinologist A Toogood (Birmingham)

10:00 – 12:00 Clinical Management Workshop 4: INTERFACES BETWEEN ENDOCRINOLOGY

AND INTERNAL MEDICINE Chairs: J Bevan (Aberdeen) & A Brooke (London)

Amiodarone-associated hyperthyroidism, a practical guide to investigation and therapy A Weetman (Sheffield)

Epilepsy in women – what are the endocrine, metabolic and reproductive health considerations? M Morrell (Stanford, USA)

Iatrogenic adrenal suppression: diagnosis and management P Stewart (Birmingham)

Hyponatraemia: investigation and management C Thompson (Dublin, Ireland)

12:00 – 12:45 Clinical Expert 3: Repeat

TURNER SYNDROME – HOW TO SMOOTH THE TRANSITION BETWEEN PAEDIATRIC AND ADULT CLINIC Generously supported by Ipsen Ltd Chair: G Conway (London)

M Davies (London)

12:00 – 12:45 Clinical Expert 4: Repeat VITAMIN D DEFICIENCY,

DIAGNOSIS AND MANAGEMENT Chair: P Selby (Manchester)

Z Mughal (Manchester)

12:45 – 13:30 Clinical Expert 5: Repeat DIFFERENTIAL DIAGNOSIS OF CUSHING’S

Chair: K Meeran (London) A Grossman (London)

12:45 – 13:30 Clinical Expert 6: Repeat THE TIRED PATIENT

Chair: S Aylwin (London) J Miell (London)

SCIENTIFIC PROGRAMMETHURSDAY 19 MARCH 2009


DEADLINE FOR RECEIPT OF ABSTRACTS:

15 NOVEMBER 2008Please submit your abstract online at: www.endocrinology.org/meetings/2009/sfebes2009/abstracts.html

All abstracts should be sent as soon as possible to arrive no later than 15 November 2008. Any abstracts received after this date will not be considered.

The abstract must be no longer than 300 words (including numbers and symbols). A category must be selected for your abstract. Please select one from the following list and indicate this category clearly on your submission:

Bone Clinical practice/governance and case reports Cytokines and growth factors Diabetes, metabolism and cardiovascular Endocrine tumours and neoplasia Growth and development Neuroendocrinology and behaviour Pituitary Reproduction Steroids Thyroid

Accepted abstracts will be published in Endocrine Abstracts, both in print and on the web, and are accepted on the understanding that the work has not been published or presented elsewhere in substantially the same form. Submission of an abstract assumes approval in advance of the meeting in both the web and print versions of Endocrine Abstracts. Copyright of accepted abstracts will automatically be assigned to BioScientifica Ltd – submission indicates your agreement to this. Abstracts are also accepted on the understanding that they will be presented at the meeting either as a poster or as an oral presentation. Any author failing to present an accepted abstract at this meeting will automatically be excluded from submitting any future abstracts.

The Programme Committee reserves the right of final decision regarding acceptance of abstracts and the form of presentation. Notification of acceptance or rejection will be sent to authors in January 2009. Detailed instructions concerning oral presentations and poster sessions will be mailed to qualifying authors with notification of acceptance.

Please note, abstracts that are accepted as poster presentations will need to be displayed on 2x1 metre LANDSCAPE poster boards.

All abstracts must be submitted online. Full details can be found at the web address below:

www.endocrinology.org/meetings/2009/sfebes2009/abstracts.html

PRIzES FOR YOUNG ENDOCRINOLOGISTS*A number of prizes will be available for Young Endocrinologists* who submit a high-scoring accepted abstract. There will be prizes for the two highest scoring oral communication presentations and the two overall highest scoring poster presentations. Also available will be up to two prizes for poster presentations in each submitted category.*Not yet achieved a PhD/less than 6 years post doc/not yet completed medical training

CLINICAL CASE POSTERSPosters in the ‘Clinical practice/governance and case reports’ category will be reviewed by a panel of established endocrinologists in order to provide constructive feedback to authors. Those of high quality will be endorsed by the panel.

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SUBMISSIONOF ABSTRACTS


THE EXPERT’S VIEWInvitation for Clinical CasesDelegates attending the Society for Endocrinology BES 2009 in Harrogate are invited to submit clinical cases for discussion in the ‘Clinical Expert’ sessions. Three interesting or controversial cases will be selected for each of the topics, which are as follows:

Tuesday 17 March Thyroid eye disease (clinical evaluation and classification – EUGOGO) P Perros (Newcastle-upon-Tyne)

Delayed puberty J Kirk (Birmingham)

Wednesday 18 & Thursday 19 March Turner Syndrome – how to smooth the transition between paediatric and adult clinic M Davies (London)

Vitamin D deficiency, diagnosis and management Z Mughal (Manchester)

Thursday 19 March Differential diagnosis of Cushing’s A Grossman (London)

The tired patient J Miell (London)

The authors of the selected cases will be asked to present their case for 5 minutes, after which the expert will comment and open the discussion. The case should not be rare or exotic but, rather, should focus on practical aspects of research, clinical diagnosis and/or management. Please note cases selected will also be required to be presented in the repeat sessions.

The synopsis of your case should be sent in a Word document, as an attachment to an email to: [email protected]. Your synopsis should be no more than 300 words.

DEADLINE FOR RECEIPT: 23 January 2009

REGISTRATIONPlease register online at: www.endocrinology.org/meetings/2009/sfebes2009/registration.aspx. A confirmation of receipt will be sent via email upon registration and a detailed booking confirmation will be sent by post. Registration for social events must be booked in advance at the time of registration in order to secure a place.

There is no deadline for the receipt of registration forms, but please note that a surcharge will be made for registrations received after Monday 19 January 2009. No refunds will be made after this date – refund requests received before will be subject to an administrative charge of £15.

Registration fees for participants include access to all sessions, tea and coffee, lunches on Monday, Tuesday and Wednesday, access to the commercial exhibition and Welcome Reception, programme and abstract books.

Reduced registration fees are available for members of the Society for Endocrinology. If you are not a member of the Society for Endocrinology and would like to apply please go to: www.endocrinology.org/membership

You may register at the members’ rate if we receive an application to join from you at the same time.

Members of the Society for Endocrinology £270 (£310 after 19 January 2009)

Non-members of the Society for Endocrinology £350 (£390 after 19 January 2009)

Concessionaries* £160 (£200 after 19 January 2009)

*Non-clinically qualified research students, postdoctoral fellows and nurses who have no access to funding.

Please note: day delegate rates are not may sometimes be made. There will be a limited number of these places available, if you wish to be considered please email your request to [email protected]

Online registration is available at: www.endocrinology.org/meetings/2009/sfebes2009/registration.aspx

Early bird deadline: 19 January 2009

FREE REGISTRATIONSSenior and Honorary MembersAll Senior and Honorary Members of the Society for Endocrinology are entitled to free registration at this meeting.

Free Places!

The Society is pleased to announce a limited number of free places for trainee scientists, clinicians and nurses. Successful applicants will receive a complimentary meeting package, which

THE EXPERT’S VIEW &REGISTRATION


includes registration fees, accommodation for the duration of the meeting, and reimbursement of economy-class travel expenses upon submission of receipts after the event. Successful applicants will each receive a prize certificate. A fantastic package worth up to a maximum of £750!

Applications will only be accepted from Full / Ordinary Members of the Society on behalf of promising young trainees who have not yet chosen their specialty. In order to apply, please complete the application form available at: www.endocrinology.org/grants

Please note, there are a limited number of free places available, and will be awarded on a first come first served basis. Current members of the Society are not eligible for this prize, as they are deemed to have already chosen endocrinology as their specialty. However, members may apply for a conference grant, please see details at: www.endocrinology.org/grants.

Applications will be welcome from 3 November 2008, with a strict deadline of 1 December 2008. Applications received before the opening date will not be accepted.

Please submit applications to: [email protected]

CATERINGComplimentary tea and coffee will be available during scheduled breaks throughout the meeting. Lunch is included in the cost of registration for Monday 16, Tuesday 17 and Wednesday 18 March 2009. Delegates are requested to indicate any special dietary requirements in advance using the online registration form.

ACCOMMODATIONThere is a wide variety of accommodation in Harrogate, ranging from comfortable budget-conscious options through to luxury hotels.

The conference headquarters hotel is the Majestic. A full list of accommodation is available online.

Please book your accommodation through Reservation Highway online at: www.endocrinology.org/meetings/2009/sfebes2009/accommodation.html

Book early to ensure the hotel of your choice.

Please contact Reservation Highway direct for any other accommodation queries.

Tel: +44 (0)1423 525577 Fax: +44 (0)1423 525599 Email: [email protected]

PROGRAMME BOOkSProgramme books can be collected upon registration at the meeting.

ABSTRACT BOOkSAbstracts from the meeting will be published in the journal Endocrine Abstracts, which will be in the conference wallets distributed at the meeting.

The journal is available to those not registering for the meeting at a cost of £35 plus postage.

Abstracts will also be displayed electronically before the meeting on the conference website.

CPD APPROVALThis event has been approved by the Royal College of Physicians for 23 external credits, activity code 42366.

TRAVEL GRANTSIn addition to any travel grants offered by other societies, funding for travel is available from the Society for Endocrinology/Clinical Endocrinology Trust for members of the Society for Endocrinology. The deadline for receipt of completed forms is 15 December 2008.

Full details and application forms are available at: www.endocrinology.org/grants or from the Society for Endocrinology, 22 Apex Court, Woodlands, Bradley Stoke, Bristol BS32 4JT, UK (Tel: +44 (0) 1454 642200; Fax: +44 (0) 1454 642205; Email: [email protected]).

COMMERCIAL EXHIBITIONThe exhibition will be open from Monday 16 March through to Thursday 19 March. Delegates will have the opportunity to meet representatives from a number of publishers and pharmaceutical, diagnostic and equipment companies at their stands to discuss new developments and receive up-to-date product information.

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GENERAL INFORMATION


YOUNG ENDOCRINOLOGISTS*PrizesA number of prizes will be available for Young Endocrinologists. Prizes will be awarded to the two top-scoring oral communications and two top-scoring poster presentations, one basic science and the other clinical. Prizes will also be awarded by category of submission. There will be up to two prizes for poster presentations in each category. If you would like to be considered for these prizes please tick the Young Endocrinologist box on the abstract submission form.

Quiz EveningJoin your fellow trainees and established endocrinologists on Monday 16 March for an evening of fun and trivia. A light-hearted evening, where you can enjoy a drink and test your general knowledge. A great way to socialise and wind down from the day’s activities.

AWARDSIf you would like to be considered for the awards listed below, please indicate your interest on the online abstract submission form at: www.endocrinology.org/meetings/2009/bes2009/abstracts.html

British Thyroid Association Award The British Thyroid Association will offer an award to a young researcher who submits a high-scoring abstract in the ‘Thyroid’ category, where the first author is under the age of 35.

Association for Multiple Endocrine Neoplasia Disorders (AMEND) Young Investigators’ Award This award is run in association with the Society for Endocrinology. The first author of the highest scoring abstract in the ‘Endocrine tumours and neoplasia’ category will receive a £300 honorarium, certificate and medal. Criteria for eligibility is as follows:

• Applicants must be 35 years of age or less

• Must be studying for a higher degree, e.g. PhD/MD or within three years of completing a higher degree

• Must be a UK citizen or the research must have primarily taken place in the UK

• Abstracts must be on the subject of the combined or individual conditions associated with MEN1, MEN2a, MEN2b or FMTC

The winning abstract author will be required to present their work at the AMEND AGM. This will be held on Saturday 9 May 2009 in Exeter. Travel expenses will be reimbursed by AMEND in accordance with the AMEND expenses policy.

Clinical Case Posters Posters in the ‘Clinical practice/governance and case reports’ category will be reviewed by a panel of established endocrinologists in order to provide constructive feedback to authors. Those of high quality will be endorsed by the panel.

NURSES’ POSTER SESSIONAll posters displayed at the meeting where one of the authors is a nurse will be displayed in a separate session on Wednesday 18 March at 16:15 – 16:45. Please indicate that it is a Nurse submission when uploading your abstract. Further details will be sent upon acceptance of your abstract.

*Not yet achieved a PhD/less than 6 years post doc/not yet completed medical training

GENERAL INFORMATION & AWARDS


DEADLINESSubmission of abstracts: Saturday 15 November 2008

Free trainee applications: Monday 1 December 2008

Society for Endocrinology/Clinical Endocrinology Trust travel grant applications: Monday 15 December 2008

Registration cancellations: Monday 19 January 2009

The Expert’s view call for clinical cases: Friday 23 January 2009

THE TOWNHarrogate is a pleasant spa town to the south-east of the Yorkshire Dales, famous for its tea shops, flower shows, Turkish baths and antique shops. The town is also famous for its associations with the great English crime novelist Agatha Christie, who disappeared here for a few days in the 1930s!

THE CONFERENCE VENUEWithin walking distance of the town centre, the Harrogate International Centre is a versatile conference and exhibition space and is the second largest venue outside London. The conference auditorium seats 2000 and has many breakout rooms and exhibition areas.

TRANSPORT LINkS TO HARROGATEBy train:

Mainline services are to Leeds and York, then regional railways to Harrogate. The Conference Centre is 10–15 minute walk from the station. A taxi fare is approximately £4.00.

By car:

From London: M1 and then A1 (M), exit at Wetherby. Harrogate is 9 miles from this exit. From the North: A1, exit at Wetherby or Knares-borough. Harrogate is 8 miles from this exit. From the East: M621 and A1 (M), exit at Wetherby.From the West: M56, M62 and A1 (M), exit at Wetherby.

By air:

Leeds Bradford International Airport is a 20 minute drive from Harrogate. Alternatively, Manchester Airport is a 75 minute drive.

SOCIAL PROGRAMMEMonday 16 March Welcome Reception 19:00, Majestic Hotel Join your fellow conference attendees for drinks and canapés in the North/South Lounge at the Majestic Hotel. A great introduction to the meeting and Harrogate town.

Young Endocrinologists’* Quiz Night 19:45, Harrogate International Centre Join your fellow Young Endocrinologists* for an evening of fun and trivia. A light-hearted evening where you can enjoy a drink and test your general knowledge. A great way to socialise and wind down from the day’s activities.

*Not yet achieved a PhD/less than 6 years post doc/not yet completed medical training

Tuesday 17 March Conference dinner 19.30, The Majestic Hotel Tickets £25.00 A great way to socialise and network in relaxed surroundings. Help yourself to an array of hot and cold food followed by a little dancing for those who desire. A bar will be available, a great opportunity to let your hair down and mingle with your friends and peers.

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GENERAL INFORMATION& SOCIAL PROGRAMME


MAP OF HARROGATE


Grove Road

Skipton Road

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Dragon Avenue

Dragon Parade

Westmoreland Street

Regent Parade

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Knaresborough Road

Wetherby Road A661

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York Place

North Park Road

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Albert Street

Raglan Street

Victoria Avenue

Tower Street

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Otley Road B6162

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Jenny Field Drive

Kent Road

Duchy Road

York Road

Cornwall Road

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Cresent Road

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Esplanade

Montpellier

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West P

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Station P

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James Street

Cambridge Street

Oxford Street

Kings Road

Cheltenham

Parade

Cheltenham Mt

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Alexandra Rd

Studley RdFranklin M

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Springfield Avenue

Coppice DriveR

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Disabled Toilets

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OAKDALE GOLF COURSE

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A61 to Ripon& A1(M) North

Harlow CarrBotanical Gardens

A61 to Leeds& M1 South

A59 toKnaresborough& A1(M) South

HarrogateDistrictHospital

A1(M) South

1. The Hydra Swimming/

Leisure Centre

2. Royal Hall

3. Exhibition Centre

4. Conference Centre

5. Tourist Information Centre

6. Post Office

7. Harrogate Theatre

8. Council Offices

9. Victoria Shopping Centre

10. Rail Station

11. Odeon Cinema

12. Police Station

13. Mercer Art Gallery

14. Royal Pump Room Museum

15. Cairn Hotel

16. Crown Hotel

17. Holiday Inn

18. Hotel du Vin

19. Majestic Hotel

20. St. George Swallow Hotel

21. Old Swan Hotel

22. The Yorkshire

23. Kimberley Hotel

24. Cedar Court Hotel

25. Grants Hotel

26. Studley Hotel

27. White Hart Hotel

28. Sun Pavilion

29. Public Library

30. Cenotaph

31. Bus Station

32. Turkish Baths

33. Coach Park

34. Harrogate Registrar Office

TIMETABLE

SOCIETY fOR ENDOCRINOLOGY BES 2009

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LunchRegistration

Symposium 1: Finding the right balance of dietary and metabolic influences in fetal and adult life

Clinical Management Workshop 1: Measuring hormones: what does your result mean?

Applied Physiology WorkshopMetabolic phenotyping in human endocrine disorders

Coffee Tea

Symposium 2: Calcium conundrums: too high, too low and what to do

Oral Communications 1


WelcomeReception

Society for Endocrinology Jubilee Medal Lecture

PCOS Special Interest Group Satellite

Steroids Special Interest Group Satellite

Pituitary Special Interest Group Satellite

Young Endocrinologists Quiz Night

Young Endocrinologists Prize Lectures

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Session Type KeyB = Basic ScienceC = Clinical

Clinical Expert 1: Thyroid eye disease

Clinical Expert 2: Delayed puberty

Symposium 3: What’s WNT – a novel signalling pathway in endocrinology


Clinical Management Workshop 2: Improving mortality and morbidity in pituitary disease

Lunch & postersCoffee

Society for Endocrinology Dale Medal Lecture M Thorner (Charlottesville, USA)

Society for Endocrinology Transatlantic Medal Lecture L Jameson (Chicago, USA)

Symposium 4: What is the TSH set point? Does it matter?


Young Endocrinologists Symposium: The ‘how-to’ guide on scientific communication

Tea

Clinical Debate: This house believes that radioactive iodine is the first line of treatment for Graves’ disease

Clinical Expert 1: Repeat



Symposium 5: The endoplasmic reticulum – an important link between inflammation, stress and diabetes

Conference Dinner

Clinical Expert 3: Turner Syndrome – how to smooth the transition between paediatric and adult clinic

Clinical Expert 4: Vitamin D deficiency, diagnosis and management

Symposium 6: Polycystic Ovarian Syndrome (PCOS): when does it start, why and what to do about it?

Symposium 7: Phosphoinositide 3- kinase (PI3K) signalling in health and disease: an old system with new potential

Nurses session 1

Society for Endocrinology Annual General Meeting

Andrology Special Interest Group Satellite

Novo Nordisk Satellite Coffee

Society for Endocrinology European Medal Lecture W Wiersinga (Amsterdam, Netherlands)

European Society of Endocrinology talk

Society for Endocrinology International Medal Lecture M Kawata (Kyoto, Japan)

Lunch & posters

Symposium 8: Novel aspects of bone physiology in relation to osteoporosis treatment

Symposium 9: Kisspeptin a Novel Regulator of puberty and fertility

Nurses session 2

Tea

British Thyroid Association Pitt-Rivers Lecture L Hegedüs (Odense, Denmark)

Clinical Endocrinology Visiting Professor Lecture M Molitch (Chicago, USA)

Awards ceremony

Clinical Expert 5: Differential diagnosis of Cushing’s

Clinical Expert 6: The tired patient

Society for Endocrinology Medal Lecture A Hattersley (Exeter)

Clinical Endocrinology Trust Lecture D Johnston (London)

Clinical Management Workshop 3: Endocrine consequences of cancer treatment

Clinical Management Workshop 4: Interfaces between endocrinology and internal medicine




Clinical Expert 6: RepeatCoffee

CONFERENCE SECRETARIAT Society for Endocrinology 22 Apex Court Woodlands Bradley Stoke Bristol BS32 4JT, UK

Tel: +44 (0)1454 642210 Fax: +44 (0)1454 642222 Email: [email protected] Website: www.endocrinology.org

The Society for Endocrinology Company Limited by Guarantee Registered in England No 349408 Registered office as shown above Registered Charity No 266813

SOCIETY FOR ENDOCRINOLOGY BES 2009

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