Trends in Biotechnology, 34(9), 689-99. [email protected]Assistant Professor School of Mechanical & Aerospace Engineering College of Engineering Wai Yee Yeong - Google Scholar Citations scholar.google.com.sg/citations?user=CgowDcwAAAAJ&hl=en Skin bioprinting: Impending reality or fantasy?
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F. Rengier, A. Mehndiratta, H. von Tengg-Kobligk, C. M. Zechmann, R. Unterhinninghofen, H.-U. Kauczor, et al., "3D printing based on imaging data: review of medical
applications," International journal of computer assisted radiology and surgery, vol. 5, pp. 335-341, 2010.
Rúben F Pereira; Cristina C Barrias; Pedro L Granja; Paulo J Bartolo Advanced Biofabrication Strategies for Skin Regeneration and Repair
Nanomedicine. 2013;8(4):603-621.
Wake Forest School of Medicine
Bioprinting: Process Flow
3D bioprinting of tissues and organs, NATURE BIOTECHNOLOGY(2014), Sean V Murphy & Anthony Atala
Bioprinting Techniques
Print Format
Cell spheroids Cells-laden gelCell suspension
Multi-layered culture of human skin fibroblasts and keratinocytes through 3-D
freeform fabrication
• Materials & cells:• Materials: Collagen type I (rat tail), 2.05 mg/mL• Cells: Primary adult human dermal FB and KC (1mil/mL for both)
W. Lee, J. C. Debasitis, V. K. Lee, J.-H. Lee, K. Fischer, K. Edminster, et al., "Multi-layered culture of human skin
fibroblasts and keratinocytes through three-dimensional freeform fabrication," Biomaterials, vol. 30, pp. 1587-1595, 3//
Applications: Development of bioprinted skin models (May2015)
Concept: Bioprinting of tissue spheroids to fabricatebioprinted tissue (based on Organovo’s exVive3D liver model)
Potential in Digital Pre-Processing
• Developing natural-looking, 3D-printed skin
• 3D camera technology, image processing and and skin modelling techniques that can almost exactly match an individual's skin tone and skin texture under varying light sources