Sircol Citations 2015 Murine Aneuploid Fibrosarcoma Cell ...

Sircol Citations

2015

Murine Aneuploid Fibrosarcoma Cell Line (L929)

Aramwit, P., & Jaichawa, N. (2015). A comparative study of type A and type B gelatin nanoparticles as the controlled release carriers for different model compounds. Materials Express 5, 241 – 248. Retrieved from http://www.ingentaconnect.com/content/asp/me/2015/00000005/00000003/art00009

Human Carotid Plaques

Asciutto, G., Dias, N., Edsfeldt, A., & Nitulescu, M. (2015). Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke. PloS One doi: 10.1371/journal.pone.0121086. Retrieved from http://dx.plos.org/10.1371/journal.pone.0121086

Bone Marrow-Derived Mesenchymal Stem Cells

Ba, R., Wei, J., Li, M., & Cheng, X. (2015). Cell-bricks based injectable niche guided persistent ectopic chondrogenesis of bone marrow-derived mesenchymal stem cells and enabled nasal augmentation. Stem Cell Research & Therapy 6, 16. Retrieved from http://www.biomedcentral.com/content/pdf/s13287-015-0006-4.pdf

Human Airways

Balenga, N., Klichinsky, M., & Xie, Z. (2015). A fungal protease allergen provokes airway hyper-responsiveness in asthma. Nature Communications 6, Article Number 6763. Retrieved from http://www.nature.com/ncomms/2015/150413/ncomms7763/full/ncomms7763.html

Human Mesenchymal Stem Cells

Barati, D., & Walters, J. (2015). Effect of Organic Acids on Calcium Phosphate Nucleation and Osteogenic Differentiation of Human Mesenchymal Stem Cells on Peptide Functionalized Nanofibers. Langmuir doi: 10.1021/acs.langmuir.5b00615. Retrieved from http://pubs.acs.org/doi/abs/10.1021/acs.langmuir.5b00615

Human Mesenchymal Stem Cells

Boda, S., Thrivikraman, G., & Basu, B. (2015). Magnetic field assisted stem cell differentiation–role of substrate magnetization in osteogenesis. Journal of Materials Chemistry B 3, 3150 – 3168. Retrieved from http://pubs.rsc.org/en/content/articlehtml/2015/tb/c5tb00118h

Human Orbital Fibroblasts

Bo-ding, T., Man-Yi, X., Jie-Xi, Z., & Wei, X. (2015). MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy. Molecular Vision 21, 324 – 334. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384173/

Mouse Lung

Bronova, I., & Smith, B. (2015). Peripheral Targeting of CB1 Cannabinoid Receptors Protects from Radiation-Induced Pulmonary Fibrosis. American Journal of Resp Cell Mol Biol. doi: 10.1165/rcmb.2014.03310c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0331OC

Human and Mouse Lung Samples

Calhoun, C. (2015). Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs. The Journals of Gerontology A Biol Sci Med Sci doi: 10.1093/Gerona/glu241/. Retrieved from http://biomedgerontology.oxfordjournals.org/content/early/2015/01/07/gerona.glu241.short

Human Bone Marrow-Derived Mesenchymal Stem Cells

Castro, N., Patel, R., & Zhang, L. (2015). Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration. Cellular and Molecular Bioengineering doi: 10.1007/s12195-015-0389-4. Retrieved from http://link.springer.com/article/10.1007/s12195-015-0389-4

Mouse Fibroblasts

Chang, B., Choi, Y., & Kim, J. (2015). Collagen complexes increase the efficiency of iPS cells generated using fibroblasts from adult mice. Journal of Reproduction and Development 2, 145 – 153. Retrieved from http://doi.org/10.1262/jrd.2014-081.

Human Annulus Fibrosus Cells

Chen, M., Sun, J., & Liao, S. (2015). Low-intensity pulsed ultrasound stimulates matrix metabolism of human annulus fibrosus cells mediated by transforming growth factor β 1 and extracellular signal-regulated kinase pathway. Connective Tissue Research doi: 10.3109/03008207.2015.1016609. Retrieved from http://informahealthcare.com/doi/abs/10.3109/03008207.2015.1016609

Human Skin Fibroblasts

Chiang, H., & Chan, S. (2015). Fisetin ameliorated photodamage by suppressing the MAP kinase/MMP pathway and NF-κB pathways. Journal of Agricultural and Food Chemistry doi: 10.1021/jf502500t. Retrieved from http://pubs.acs.org/doi/abs/10.1021/jf502500t

Primary Cardiac Fibroblasts

Chichger, H., & Vang, A. (2015). PKC δ and βII regulate angiotensin II-mediated fibrosis through p38: a mechanism of RV fibrosis in pulmonary hypertension. American Journal of Physiology Lung Cellular and Molecular Physiology 308, L827 – L836. Retrieved from http://ajplung.physiology.org/content/308/8/L827.abstract

Human Nasal Polyp-Derived Fibroblasts

Cho, J., Kang, J., & Shin, J. (2015). Inhibitory Effect of Delphinidin on Extracellular Matrix Production via the MAPK/NF-κB Pathway in Nasal Polyp-Derived Fibroblasts. Allergy, Asthma & Immunol. Res. 7, 276 – 282. Retrieved from http://synapse.koreamed.org/search.php?where=aview&id=10.4168/aair.2015.7.3.276&code=0166AAIR&vmode=FULL

Dog Hind Leg Wound

Das, J., Nath, I., & Routray, P. (2015). Cell-based therapy and rehabilitation with prosthetic limbs in a dog. Turkish Journal of Veterinary and Animal Sciences 39, 115 – 119. Retrieved from http://mistug.tubitak.gov.tr/bdyim/abs.php?dergi=vet&rak=1404-95

Chondrocytes

Díaz-Rodríguez, P., & Landin, M. (2015). Controlled release of indomethacin from alginate–poloxamer–silicon carbide composites decrease in-vitro inflammation. International Journal of Pharmaceutics 480, 92 – 100. Retrieved from http://www.sciencedirect.com/science/article/pii/S0378517315000344

Cardiac Fibroblasts

Dong, X., Liu, S., Zhang, L., & Yu, S. (2015). Downregulation of miR‐21 is Involved in Direct Actions of Ursolic Acid on the Heart: Implications for Cardiac Fibrosis and Hypertrophy. Cardiovascular Therapeutics doi: 10.1111/1755-5922.12125. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/1755-5922.12125/abstract

Rat Liver

Douhara, A., & Moriya, K. (2015). Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic. Molecular Medicine Reports 11, 1693 – 1700. Retrieved from http://www.spandidos-publications.com/mmr/11/3/1693

Neonatal Rat Lung

Drummond, S., Ramachandran, S., & Torres, E. (2015). CXCR4 Blockade Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats. Neonatology 107, 304 – 311. Retrieved from http://www.karger.com/Article/Abstract/371835

Guinea Pig Dermal Wound

Farahani, F., & Fattahian, H. (2015) Experimental Study on Ostrich Acellular Dermal Matrix in Repair of Full-Thickness Wounds of Guinea Pig. Kafkas Univ Vet Fak Derg doi: 10.9775/kvfd.2015.13212. Retrieved from http://vetdergi.kafkas.edu.tr/inpress/13212.pdf

Mouse Lung

Fattah, E., & Bhattacharya, A. (2015). Critical Role for IL-18 in Spontaneous Lung Inflammation Caused by Autophagy Deficiency. The Journal of Immunology doi: 10.4049/jimmunol.1402277. Retrieved from http://www.jimmunol.org/content/early/2015/04/17/jimmunol.1402277.short

Human Colonic Subepithelial Myofibroblasts

Fotiadis, K., Filidou, E., & Arvanitidis, K. (2015). Intraperitoneal application of phospholipids for the prevention of post-operative adhesions: a possible role of myofibroblasts. Journal of Surgical Research doi: http://dx.doi.org/10.1016/j.jss.2015.04.036. Retrieved from http://www.sciencedirect.com/science/article/pii/S002248041500431X

Human Lung Fibroblasts

Fu, C., Odegaard, J., & Hsieh, M. (2015). Macrophages are required for host survival in experimental urogenital schistosomiasis. The FASEB Journal 29, 193 – 207. Retrieved from http://www.fasebj.org/content/29/1/193.short

Rat Submandibular Glands

Gao, Z., Wu, T., Xu, J., Liu, G., Xie, Y., & Zhang, C. (2015). Generation of Bioartificial Salivary Gland Using Whole-Organ Decellularized Bioscaffold. Cells Tissues Organs doi: 10.1159/000371873. Retrieved from http://www.karger.com/Article/Abstract/371873

Porcine Dermis

Greco, K., & Francis, L. (2015). Characterisation of porcine dermis scaffolds decellularised using a novel non-enzymatic method for biomedical applications. Journal of Biomaterials Applications doi: 10.1177/0885328215578638. Retrieved from http://jba.sagepub.com/content/early/2015/04/08/0885328215578638.abstract

Human Mesenchymal Stem Cells

Green, D., Kwon, H., & Jung, H. (2015). Osteogenic Potency of Nacre on Human Mesenchymal Stem Cells. Molecules and Cells 38, 267 – 272. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363727/

Human Periodontal Ligament Cells

Hasegawa, D., & Wada, N. (2015). Wnt5a Induces Collagen Production by Human Periodontal Ligament Cells through TGFβ1‐mediated Upregulation of Periostin Expression. Journal of Cellular Physiology doi: 10.1002/jcp.24950. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jcp.24950/abstract

Mouse Skin

Herro, R., & Antunes, R. (2015). The Tumor Necrosis Factor Superfamily Molecule LIGHT Promotes Keratinocyte Activity and Skin Fibrosis. Journal of Investigative Dermatology doi: 10.1038/jid.2015.110. Retrieved from http://www.nature.com/jid/journal/vaop/ncurrent/full/jid2015110a.html

Human Lung Fibroblasts

Horie, M., Saito, A., & Yamaguchi, Y. (2015). Three-dimensional Co-culture Model for Tumor-stromal Interaction. JoVE (Journal of Vis. Exp.) 96, e52469. Retrieved from http://www.jove.com/video/52469/three-dimensional-co-culture-model-for-tumor-stromal-interaction

Mouse Lung

House, J., Li, H., DeGraff, L., & Flake, G. (2015). Genetic variation in HTR4 and lung function: GWAS follow-up in mouse. The FASEB Journal 29, 323 – 335. Retrieved from http://www.fasebj.org/content/29/1/323.short

Human Dermal Fibroblasts and Mouse Skin

Huang, J., Beyer, C., & Palumbo-Zerr, K. (2015). Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2014-207109. Retrieved from http://ard.bmj.com/content/early/2015/04/09/annrheumdis-2014-207109.short

Human Liver Cell Line (HepG2)

Hussein, K., & Park, K. (2015). Three dimensional culture of HepG2 liver cells on a rat decellularized liver matrix for pharmacological studies. Journal of Biomedical Marterials Research doi: 10.1002/jbm.b.33384. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33384/full

Mouse MMP19-/- Lung Fibroblasts

Jara, P., Calyeca, J., & Romero, Y. (2015). Matrix metalloproteinase (MMP)-19 deficient fibroblasts display a profibrotic phenotype. American Journal of Physiology Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00043.2014. Retrieved from http://ajplung.physiology.org/content/early/2015/01/09/ajplung.00043.2014.abstract

Rat Tail Collagen

Kadziński, L. (2015). Effect of Silicone on the Collagen Fibrillogenesis and Stability. Journal of Pharmaceutical Sciences doi: 10.1002/jps.24351. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jps.24351/full

Mouse Renal Tissue

Kamata, M., Hosono, K., & Fujita, T. (2015). Role of cyclooxygenase-2 in the development of interstitial fibrosis in kidneys following unilateral ureteral obstruction in mice. Biomedicine & Pharmacotherapy doi: 10.1016/j.biopha.2015.01.010. Retrieved from http://www.sciencedirect.com/science/article/pii/S0753332215000256

Human Mesenchymal Stem Cells

Karimi, T., Barati, D., & Karaman, O. (2015). A developmentally inspired combined mechanical and biochemical signaling approach on zonal lineage commitment of mesenchymal stem cells in articular cartilage. Integrative Biology 7, 112 – 127. Retrieved from http://pubs.rsc.org/en/content/articlehtml/2014/ib/c4ib00197d

Mouse Lung

Karmouty-Quintana, H., Philip, K., & Acero, L. (2015). Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. The FASEB Journal 29, 50 – 60. Retrieved from http://www.fasebj.org/content/29/1/50.short

Mouse Skin

Kavian, N., Marut, W., & Servettaz, A. (2015). Pantethine prevents murine systemic sclerosis in the mouse through the inhibition of microparticle shedding. Arthritis & Rheumatology doi: 10.1002/art.39121. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/art.39121/abstract

Human Adipose-Derived Stem Cells

Kim, S., & Jung, Y. (2015). TGF-β 3 encapsulated PLCL scaffold by a supercritical CO 2–HFIP co-solvent system for cartilage tissue engineering. Journal of Controlled Release 206, 101 – 107. Retrieved from http://www.sciencedirect.com/science/article/pii/S0168365915002047

Human Dermal Fibroblast Cells

Kim, Y., Huh, J., Lim, Y., & Cho, M. (2015). Soy Isoflavone Glycitin (4’‐Hydroxy‐6‐Methoxyisoflavone‐7‐D‐Glucoside) Promotes Human Dermal Fibroblast Cell Proliferation and Migration via TGF‐β Signaling. Phytotherapy Research doi: 10.1002/ptr.5313. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/ptr.5313/full

Human Allogeneic Vein Valves From Cadavers

Kuna, V., Rosales, A., & Hisdal, J. (2015). Successful tissue engineering of competent allogeneic venous valves. Journal of Vascular Surgery: Venous and Lymphatic Disorders doi: 10.1016/j.jvsv.2014.12.002. Retrieved from http://www.sciencedirect.com/science/article/pii/S2213333X15000049

Porcine Tracheal Scaffolds and Human Tracheae

Lange, P., & Greco, K. (2015). Pilot study of a novel vacuum‐assisted method for decellularization of tracheae for clinical tissue engineering applications. Journal of Tissue Engineering and Regenerative Medicine doi: 10.1002/term.1979. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/term.1979/full

Mouse Lung

Lee, D., Walker, S., Byrne, A., & Gregory, L. (2015). Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life. Thorax doi: 10.1136/thoraxjnl-2014-205280. Retrieved from http://thorax.bmj.com/content/early/2015/04/03/thoraxjnl-2014-205280.full?g=w_thorax_open_tab

Bovine Joint Articular Chondrocytes

Lee, J., Gegg, C., & Hu, J. (2015). Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage. Arthritis Research & Therapy 17, 28. Retrieved from http://www.biomedcentral.com/content/pdf/s13075-015-0541-5.pdf

Human Ileal Strictures

Li, C., Iness, A., & Yoon, J. (2015). Noncanonical STAT3 Activation Regulates Excess TGF-β1 and Collagen I Expression in Muscle of Stricturing Crohn’s Disease. The Journal of Immunology 194, 3422 – 3431. Retrieved from http://www.jimmunol.org/content/194/7/3422.short

Human Asthma Surrogate

Li, Y., Wang, W., Huang, P., Zhang, Q., & Yao, X. (2015). Distinct sustained structural and functional effects of IL‐33 and IL‐25 on the airways in a murine asthma surrogate. Immunology doi: 10.1111/imm.12465. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/imm.12465/abstract

Human Osteoblast-Like Saos-2 Cells

Liskova, J., & Babchenko, O. (2015). Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films. International Journal of Nanomedicine 10, 869 – 884. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315565/

Fibroblasts and Epithelial Cells

Lumsden, R., & Worrell, J. (2015). Modulation of pulmonary fibrosis by IL-13Rα2. American Journal of Physiology Lung Cellular and Molecular Physiology 308, L710 – L718. Retrieved from http://ajplung.physiology.org/content/308/7/L710.abstract

Mouse Fibroblasts

Mallano, T., & Palumbo-Zerr, K. (2015). Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2014-206214. Retrieved from http://ard.bmj.com/content/early/2015/01/14/annrheumdis-2014-206214.short

Harbour Porpoise Temporomandibular Joint

McDonald, M., & Vapniarsky-Arzi, N. (2015). Characterization of the temporomandibular joint of the harbor porpoise (Phocoena phocoena) and Risso’s dolphin (Grampus griseus). Archives of Oral Biology 60, 582 – 592. Retrieved from http://www.sciencedirect.com/science/article/pii/S0003996915000126

Mice Carrying Human Pancreatic Tumour

Meng, H., Wang, M., Liu, H., Liu, X., Situ, A., & Wu, B. (2015). Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice. ACS Nano 9, 3540 – 3557. Retrieved from http://pubs.acs.org/doi/abs/10.1021/acsnano.5b00510

Human Tenocytes

Millar, N., Gilchrist, D., & Akbar, M. (2015). MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nature Communications 6, Article No. 6774. Retrieved from http://www.nature.com/ncomms/2015/150410/ncomms7774/full/ncomms7774.html

Human Fibroblasts and Mouse Lung

Mukherjee, S., Ayaub, E., & Murphy, J. (2015). Nifedipine Disrupts Signaling in Fibroblasts and Attenuates Bleomycin-Induced Fibrosis. American Journal of Cell Mol Biol doi: 10.1165/rcmb.2015-00090c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2015-0009OC

Temporomandibular Joint Disc

Murphy, M., & Arzi, B. (2015). Neocartilage integration in temporomandibular joint discs: physical and enzymatic methods. Journal of The R Soc Interface 12, pii 20141075. Retrieved from http://rsif.royalsocietypublishing.org/content/12/103/20141075.abstract

Human Lung Adenocarcinoma Cells (A549)

Nakajima, F., & Aratani, S. (2015). Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia. International Journal of Molecular Medicine 35, 110 – 116. Retrieved from http://www.spandidos-publications.com/ijmm/35/1/110?text=fulltext

Mouse Heart Tissue

O’Connor, D., Naresh, N., & Piras, B. (2015). A novel cardiac muscle‐derived biomaterial reduces dyskinesia and postinfarct left ventricular remodeling in a mouse model of myocardial infarction. Physiological Reports 3, e12351. Retrieved from http://physreports.physiology.org/content/3/3/e12351.abstract

Mouse Lung

Ohnuma, K., Hatano, R., & Aune, T. (2015). Regulation of Pulmonary Graft-versus-Host Disease by IL-26+ CD26+ CD4 T Lymphocytes. The Journal of Immunology 194, 3697 – 3712. Retrieved from http://www.jimmunol.org/content/194/8/3697.short

Human Lung Tissue and Lung Fibroblasts

Oruqaj, G., & Karnati, S. (2015). Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling. Proceedings of the National Academy of Sciences 112, E2048 – E2057. Retrieved from http://www.pnas.org/content/112/16/E2048.short

Mouse Skin

Palumbo-Zerr, K., Zerr, P., & Distler, A. (2015). Orphan nuclear receptor NR4A1 regulates transforming growth factor- signaling and fibrosis. Nature Medicine 21, 150 – 158. Retrieved from http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.3777.html

Mouse Lung

Santos, G. Dos, Rogel, M., & Baker, M. (2015). Vimentin regulates activation of the NLRP3 inflammasome. Nature Communications Article 6574, doi: 10.1038/ncomms7574. Retrieved from http://www.nature.com/ncomms/2015/150312/ncomms7574/full/ncomms7574.html

Rat Mesenchymal Stem Cells

Singh, R., Jin, G., & Mahapatra, C. (2015). Mesoporous Silica-Layered Biopolymer Hybrid Nanofibrous Scaffold: A Novel Nanobiomatrix Platform for Therapeutics Delivery and Bone Regeneration. ACS Applied Materials & Interfaces 7, 8088 – 8098. Retrieved from http://pubs.acs.org/doi/abs/10.1021/acsami.5b00692

Mouse Cardiac Tissue and Cardiac Fibroblasts

Sklepkiewicz, P., Shiomi, T., & Kaur, R. (2015). Loss of Secreted Frizzled-Related Protein-1 Leads to Deterioration of Cardiac Function in Mice and Plays a Role in Human Cardiomyopathy. Circulation: Heart Failure 8, 362 – 372. Retrieved from http://circheartfailure.ahajournals.org/content/8/2/362.short

Mouse Lung

Sun, B., Wang, X., Ji, Z., Wang, M., Liao, Y., & Chang, C. (2015). NADPH Oxidase‐Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. Small doi: 10.1002/smll.201402859. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/smll.201402859/full

Neonatal Mouse Cardiac Fibroblasts

Sun, F., Duan, W., & Zhang, Y. (2015). Simvastatin alleviates cardiac fibrosis induced by infarction via up‐regulation of transforming growth factor, beta receptor III expression. British Journal of Pharmacology doi: 10.1111/bph.13166. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/bph.13166/abstract

Human Denuded Amniotic Membrane

Taghiabadi, E., Nasri, S., & Shafieyan, S. (2015). Fabrication and characterization of spongy denuded amniotic membrane based scaffold for tissue engineering. Cell J 16, 476 – 487. Retrieved from http://oaji.net/articles/2015/109-1421148832.pdf

Mouse Lung

Tan, J., Chan, S., & Lo, C. (2015). Amnion cell mediated immune modulation following bleomycin challenge: controlling the regulatory T cell response. Stem Cell Research & Therapy 6, 8. Retrieved from http://stemcellres.com/content/6/1/8/abstract

Rat Colon

Tao, Q., Wang, B., & Zheng, Y. (2015). Triptolide ameliorates colonic fibrosis in an experimental rat model. Molecular Medicine Reports 0, 0-0. http://dx.doi.org/10.3892/mmr.2015.3582. Retrieved from http://www.spandidos-publications.com/10.3892/mmr.2015.3582

Murine Macrophage Cell Line (RAW264.7 Cells)

Tewtrakul, S., & Tungcharoen, P. (2015). Antiinflammatory and Wound Healing Effects of Caesalpinia sappan L. Phytotherapy Research doi: 10.1002/ptr.5321. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/ptr.5321/full

Mouse Lung

Thompson, E. (2015). STAT1 Attenuates Murine Allergen-Induced Airway Remodeling and Exacerbation by Carbon Nanotubes. American Journal of Resp. Cell Mol Biol doi: 10.1165/rcmb.2014-02210c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0221OC

Human Fibroblasts

Tomcik, M., Palumbo-Zerr, K., & Zerr, P. (2015). Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2014-206234. Retrieved from http://ard.bmj.com/content/early/2015/01/20/annrheumdis-2014-206234.abstract

Mouse Lung Fibroblasts

Trentin, P., & Ferreira, T. (2015). Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice. British Journal of Pharmacology doi: 10.1111/bph.13109. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/bph.13109/full

Soft-Shelled Turtle Carapace

Wang, C., & Huang, C. (2015). Effects of dietary vitamin C on growth, lipid oxidation, and carapace strength of soft-shelled turtle, Pelodiscus sinensis. Aquaculture 445, 1 – 4. Retrieved from http://www.sciencedirect.com/science/article/pii/S0044848615002136

Mouse Lung

Wang, X., Duch, M., Mansukhani, N., & Ji, Z. (2015). Use of a Pro-Fibrogenic Mechanisms-Based Predictive Toxicological Approach for Tiered Testing and Decision Analysis of Carbonaceous Nanomaterials. ACS Nano doi: 10.1021/nn507243w. Retrieved from http://pubs.acs.org/doi/abs/10.1021/nn507243w

White Rabbit Knee Trochlear Groove/Bone Marrow Cells

Wei, B., Yao, Q., Guo, Y., Mao, F., & Liu, S. (2015). Three-dimensional polycaprolactone–hydroxyapatite scaffolds combined with bone marrow cells for cartilage tissue engineering. Journal of Biomaterials Appl doi: 10.1177/0885328215575762. Retrieved from http://jba.sagepub.com/content/early/2015/03/11/0885328215575762.abstract

Pig Medial Femoral Condyle

Wei, B., Zong, M., Yan, C., & Mao, F. (2015). Use of quantitative MRI for the detection of progressive cartilage degeneration in a mini‐pig model of osteoarthritis caused by anterior cruciate ligament transection. Journal of Magnetic Resonance Imaging doi: 10.1002/jmri.24862. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jmri.24862/full

Human and Mouse Fibroblasts

Wei, J., Ghosh, A., & Chu, H. (2015). Histone deacetylase SIRT1 is reduced in systemic sclerosis and abrogates fibrotic responses by targeting TGF‐ß signaling. Arthritis & Rheumatology 67, 1323 – 1334. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/art.39061/abstract

Mouse Colon

Weiss, C., Guan, Q., Ma, Y., & Qing, G. (2015). The Potential Protective Role of Caveolin-1 in Intestinal Inflammation in TNBS-Induced Murine Colitis. PloS One 10, e0119004.. Retrieved from http://dx.plos.org/10.1371/journal.pone.0119004

Human Lung Fibroblasts

Wu, C. (2015). Preparation, Characterisation, and Controlled-Release of Biodegradable Polyester and Marine-Algae Composite. Journal of Polymers and the Environment doi: 10.1007/s10924-015-0712-0. Retrieved from http://link.springer.com/article/10.1007/s10924-015-0712-0

Human Foreskin Fibroblasts

Wu, C. (2015). Preparation and characterisation of poly (hydroxyalkanoate)/Ganoderma lucidum fibre composites: mechanical and biological properties. Polymer Bulletin doi: 10.1007/s00289-015-1307-6. Retrieved from http://link.springer.com/article/10.1007/s00289-015-1307-6

Human Foreskin Fibroblasts

Wu, T., Yang, M., & Hsu, Y. (2015). Improvement of cytocompatibility of polylactide by filling with marine algae powder. Materials Science and Engineering: C 50, 309 – 316. Retrieved from http://www.sciencedirect.com/science/article/pii/S092849311500140X

Scar Tissue from Laminectomized Rats

Xu, H., Liu, C., & Sun, Z. (2015). CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis. International Journal of Molecular Medicine 0, 0 – 0. http://dx.doi.org/10.3892/ijmm.2015.2190. Retrieved from http://www.spandidos-publications.com/10.3892/ijmm.2015.2190

Human Pulmonary Epithelial Cells

Yamada, A., Aki, T., Unuma, K., Funakoshi, T., & Uemura, K. (2015). Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells. PloS One 10, e0120192. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370722/

Rat Skin Wound

Yao, C., Yeh, J., & Chen, Y. (2015). Wound‐healing effect of electrospun gelatin nanofibres containing Centella asiatica extract in a rat model. Journal of Tissue Engineering and Regenerative Medicine doi: 10.1002/term.1992.med. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/term.1992/full

Equine Decellularised Tendon Scaffolds/Bone Marrow-Derived Mesenchymal Stem Cells

Youngstrom, D., & Rajpar, I. (2015). A bioreactor system for in vitro tendon differentiation and tendon tissue engineering. Journal of Orthopaedic Research 33, 911 – 918. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jor.22848/abstract

Rat Periodontal Ligament (PDL) Tissue and Human PDL Stem Cells

Yuda, A., Maeda, H., & Fujii, S. (2015). Effect of CTGF/CCN2 on osteo/cementoblastic and fibroblastic differentiation of a human periodontal ligament stem/progenitor cell line. Journal of Cellular Physiology 230, 150 – 159. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jcp.24693/full

Human Muscle-Derived Fibroblasts and Myoblasts

Zanotti, S., Gibertini, S., & Curcio, M. (2015). Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy. Biochimica et Biophysica Acta (BBA), Molecular Basis of Disease 1852, 1451 – 1464. Retrieved from http://www.sciencedirect.com/science/article/pii/S0925443915001192

Mouse Liver

Zhang, X., Tan, Z., Wang, Y., & Tang, J. (2015). PTPRO-Associated Hepatic Stellate Cell Activation Plays a Critical Role in Liver Fibrosis. Cellular Physiology and Biochemistry 35, 885 – 898. Retrieved from http://www.karger.com/Article/FullText/369746

Mouse Lung

Zhou, B., Flodby, P., Wang, H., Liu, Y., & Minoo, P. (2015). Effects of Endoplasmic Reticulum (ER) Stress on Epithelial Injury and Fibrosis in Alveolar Epithelial Type II Cell (AT2)-Specific Grp78 Knockout Mice. The FASEB Journal 29, no. 1 supplement 1015.4. Retrieved from http://www.fasebj.org/content/29/1_Supplement/1015.4.short

2014

Murine Model of Pancreatic Ductal Adenocarcinoma

Aguilera, K., Rivera, L., Hur, H., & Carbon, J. (2014). Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma. Cancer Research 74, 1032. Retrieved from http://cancerres.aacrjournals.org/content/74/4/1032.short

Mesenchymal Stem Cells / Mouse Lung

Akaike, Y., Kurosawa, H., Kikuchi, T., & Ichinose, M. (2014). Mesenchymal Stem Cells Correct Inappropriate Epithelial Mesenchyme Relation in pulmonary fibrosis using Stanniocalcin-1. Mol Ther doi: 10.1038/mt.2014.217. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/25373521

Fibroblast Cultures

Amara, S., Lopez, K., Banan, B., & Brown, S. (2014). Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis. Molecular Immunology 64, 26 – 35. Retrieved from http://www.sciencedirect.com/science/article/pii/S0161589014002867

Porcine Cholecyst (Gall Bladder)

Anilkumar, T. V, Vineetha, V. P., Revi, D., & ... (2014). Biomaterial properties of cholecyst‐derived scaffold recovered by a non‐detergent/enzymatic method. Journal of biomedical Materials Research Part B: Applied Biomaterials 102, 1506 – 1516. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33131/full

Mouse Lung

Arizmendi, N., & Puttagunta, L. (2014). Rac2 is involved in bleomycin-induced lung inflammation leading to pulmonary fibrosis. Respiratory Research 15, 71. Retrieved from http://www.biomedcentral.com/content/pdf/1465-9921-15-71.pdf

Mouse Embryonic and Lung Fibroblasts

Aschner, Y., Khalifah, A. P., Briones, N., Yamashita, C., & ... (2014). Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness. The American Journal of Pathology 184, 1489 – 1502. Retrieved from http://www.sciencedirect.com/science/article/pii/S000294401400090X

Rat Kidney Model

Banon-Maneus, E., Rovira, J., Ramirez-Bajo, M. J., & ... (2014). Wnt Pathway Activation in Long Term Remnant Rat Model. BioMed Research International, Article ID 324713, 10 pages. Retrieved from http://www.hindawi.com/journals/bmri/2014/324713/abs/

Marrow Stromal Cells and Endothelial Progenitor Cells

Barati, D., Moeinzadeh, S., Karaman, O., & Jabbari, E. (2014). Time Dependence of Material Properties of Polyethylene Glycol Hydrogels Chain Extended with Short Hydroxy Acid Segments. Polymer 55, 3894 – 3904. Retrieved from http://www.sciencedirect.com/science/article/pii/S0032386114004339

Mouse Pulmonary Fibroblasts

Barnes, J., & Lumsden, R. (2014). CXCR3 is Required for the IL-13 Mediated Upregulation of IL-13Rα2 in Pulmonary Fibroblasts. American Journal of Respiratory Cell and Molecular Biology doi: 10.1165/rcmb.2013-0433OC. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0433OC

Human and Rodent Lung Parenchyma

Bellaye, P. S., Burgy, O., Colas, J., Fabre, A., & ... (2014). Anti-fibrotic Role of αB-crystallin Inhibition in Pleural and Subpleural Fibrosis. American Journal of Respiratory Cell and Molecular Biol. doi: 10.1165/rcmb-2014-00110c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0011OC

Human and Rodent Lung

Bellaye, P. S., Wettstein, G., Burgy, O., & ... (2014). The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis. The Journal of Pathology 232, 458 – 472. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/path.4314/full

Aged Human Dermal Fibroblasts

Bentov, I., Damodarasamy, M., Plymate, S., & Reed, M. (2014). Decreased proliferative capacity of aged dermal fibroblasts in a three dimensional matrix is associated with reduced IGF1R expression and activation. Biogerontology 15, 329 – 337. Retrieved from http://link.springer.com/article/10.1007/s10522-014-9501-8

Human Fibroblasts and Murine sGC Knockout Fibroblasts

Beyer, C., & Zenzmaier, C. (2014). Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2013-204508. Retrieved from http://ard.bmj.com/content/early/2014/02/23/annrheumdis-2013-204508.short

Human Gut Explants

Biancheri, P., Sabatino, A. Di, & ... (2014). Absence of a role for interleukin‐13 in inflammatory bowel disease. European Journal of Immunology 44, 370 – 385. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/eji.201343524/full

Rat Activated Hepatic Stellate Cells

Birukawa, N. K., Murase, K., Sato, Y., Kosaka, A., & ... (2014). Activated hepatic stellate cells are dependent on self collagen, cleaved by membrane type 1-matrix metalloproteinase for their growth. Journal of Biological Chemistry 289, 20209 – 21. Retrieved from http://www.jbc.org/content/early/2014/05/27/jbc.M113.544494.short

Mouse Lung

Bitencourt, C., & Gelfuso, G. (2014). Hyaluronidase-loaded PLGA microparticles as a new strategy for the treatment of pulmonary fibrosis. Tissue Eng. Part A, doi: 10.1089/ten.TEA.2013.0403. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.TEA.2013.0403

Mouse Lung

Bode, C., Kinjo, T., Alvord, W. G., & Klinman, D. M. (2014). Suppressive oligodeoxynucleotides reduce lung cancer susceptibility in mice with silicosis. Carcinogenesis 35, 1078 – 1083. Retrieved from http://carcin.oxfordjournals.org/content/early/2014/02/07/carcin.bgu005.short

Human Osteoblasts

Brie, I., Soritau, O., & Dirzu, N. (2014). Comparative in vitro study regarding the biocompatibility of titanium-base composites infiltrated with hydroxyapatite or silicatitanate. Journal of Biological Engineering 8, 14. Retrieved from http://www.biomedcentral.com/content/pdf/1754-1611-8-14.pdf

Mouse Lung

Cargnoni, A., Piccinelli, E. C., Ressel, L., Rossi, D., Magatti, M., & ... (2014). Conditioned medium from amniotic membrane-derived cells prevents lung fibrosis and preserves blood gas exchanges in bleomycin-injured mice—specificity of the effects and insights into possible mechanisms. Cytotherapy 16, 17 – 32. Retrieved from http://www.sciencedirect.com/science/article/pii/S1465324913006063

Rat Skin

Chaichalotornkul, S. (2014). Secondhand smoke exposure-induced nucleocytoplasmic shuttling of HMGB1 in a rat premature skin aging model. Biochemical and Biophysical Research Communications 456, 92 – 97. Retrieved from http://www.sciencedirect.com/science/article/pii/S0006291X1402052X

Rat Kidney Tissue

Chen, C., Chou, H., & Huang, L. (2014). Maternal nicotine exposure during gestation and lactation induces kidney injury and fibrosis in rat offspring. Pediatric Research doi: 10.1038/pr.2014.148. Retrieved from http://www.nature.com/pr/journal/vaop/ncurrent/full/pr2014148a.html

Human Ligamentum Flavum Cells

Chen, M. H., Hu, C. K., Chen, P. R., Chen, Y. S., & ... (2014). Dose-dependent regulation of cell proliferation and collagen degradation by estradiol on ligamentum flavum. BMC Musculosketal Disorders 15, 238. Retrieved from http://www.biomedcentral.com/1471-2474/15/238/

Rat Achilles Tenocytes

Chen, M., Huang, Y., & Sun, J. (2014). Second messengers mediating the proliferation and collagen synthesis of tenocytes induced by low-level laser irradiation. Lasers in Medical Science doi: 10.1007/s10103.014.1658.5. Retrieved from http://link.springer.com/article/10.1007/s10103-014-1658-5

Mouse Lung

Chen, T., Nie, H., Gao, X., Yang, J., Pu, J., Chen, Z., … (2014). Epithelial–mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway. Toxicology Letters 226, 150 – 162. Retrieved from http://www.sciencedirect.com/science/article/pii/S0378427414000733

Human Skin Fibroblasts (CCD966SK)

Chen, Y., & Hwang, D. (2014). Evaluation of anti oxidant properties and biofunctions of polar, nonpolar, and water-soluble fractions extracted from gonad and body wall of the sea urchin Tripneustes. Fisheries Science doi: 10.1007/s12562-014-0808-9. Retrieved from http://link.springer.com/article/10.1007/s12562-014-0808-9

Normal Human Skin Fibroblast Cells (Detroit 551)

Chen, Y., Lee, S., Lin, Y., Chiang, S., & Lin, C. (2014). Effects of Danshensu and Salvianolic Acid B from Salvia miltiorrhiza Bunge (Lamiaceae) on Cell Proliferation and Collagen and Melanin Production. Molecules 19, 2029 – 2041. Retrieved from http://www.mdpi.com/1420-3049/19/2/2029/htm

Synovial Fluid Mesenchymal Stem Cells in a Rabbit Model

Chen, Y. P., Chen, W. C., Wang, K. C., & Chen, C. H. (2014). Effectiveness of synovial fluid mesenchymal stem cells embedded in alginate beads for treatment of steroid-induced avascular necrosis of the femoral head. Journal of Orthopaedic Sci. 19, 657 – 666. Retrieved from http://link.springer.com/article/10.1007/s00776-014-0568-5

Wound Tissue

Chereddy, K., Her, C., & Comune, M. (2014). PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing. Journal of Controlled Release 194, 138 – 147. Retrieved from http://www.sciencedirect.com/science/article/pii/S0168365914005987

Mouse Lung

Cheresh, P., & Morales-Nebreda, L. (2014). Asbestos-Induced Pulmonary Fibrosis is Augmented in 8-Oxoguanine DNA Glycosylase (OGG1) Knockout mice. American Journal of Respir Cell Mol Biol. doi: 10.1165/rcmb.2014-00380c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0038OC

Human Skin Fibroblasts

Chiang, H., Chen, C., Lin, T., & Kuo, Y. (2014). N-phenethyl caffeamide and photodamage: Protecting skin by inhibiting type I procollagen degradation and stimulating collagen synthesis. Food and Chemical Toxicology 72, 154 – 161. Retrieved from http://www.sciencedirect.com/science/article/pii/S0278691514003317

Mouse Osteoblastic Cell Line (MC3T3-E1)

Choi, E. M. (2014). Sunflower seed extract enhances the differentiation of osteoblastic MC3T3-E1 cells. Food and Agricultural Immunology 25, 9 – 19. Retrieved from http://www.tandfonline.com/doi/abs/10.1080/09540105.2012.716399

Lung Fibroblasts

Chrysanthopoulou, A. (2014). Neutrophil extracellular traps promote differentiation and function of fibroblasts. The Journal of Pathology 233, 294 – 307. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/path.4359/full

Mesenchymal Stem Cells

Chuah, Y., Kuddannaya, S., & Lee, M. (2015). The effects of poly (dimethylsiloxane) surface silanization on the mesenchymal stem cell fate. Biomaterials Science doi: 10.1039/C4BM00268G. Retrieved from http://pubs.rsc.org/en/content/articlehtml/2014/bm/c4bm00268g

Adult Male Rat Cardiac Fibroblasts

Chung, C. C., Hsu, R. C., Kao, Y. H., Liou, J. P., Lu, Y. Y., & ... (2014). Androgen Attenuates Cardiac Fibroblasts Activations through Modulations of Transforming growth factor-β and Angiotensin II Signaling. International Journal of Cardiology 176, 386 – 393. Retrieved from http://www.sciencedirect.com/science/article/pii/S016752731401287X

Mouse Lung

Chung, E., Hudak, K., & Horton, J. (2014). Transforming Growth Factor Alpha is a Critical Mediator of Radiation Lung Injury. Radiation Research 182, 350 – 362. Retrieved from http://www.rrjournal.org/doi/abs/10.1667/RR13625.1

Human Nasal Polyp-Derived Fibroblasts

Chung, S., Park, I., & Hong, S. (2014). Role of Caffeic Acid on Collagen Production in Nasal Polyp-Derived Fibroblasts. Clinical Exp Otorhinolaryngol 7, 295 – 301. Retrieved from http://synapse.koreamed.org/DOIx.php?id=10.3342/ceo.2014.7.4.295

Mouse Lung

Conte, E., Lemmolo, M., Fagone, E., Gili, E., Fruciano, M., & ... (2014). Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice. Immunobiology 219, 425 – 431. Retrieved from http://www.sciencedirect.com/science/article/pii/S0171298514000254

Human Lung Fibroblasts

Cui, Y., Osorio, J., Risquez, C., & Wang, H. (2014). Transforming Growth Factor-β1 Downregulates Vascular Endothelial Growth Factor-D Expression in Human Lung Fibroblasts via the Jun NH2-Terminal Kinase Signaling Pathway. Molecular Medicine 20, 120 – 134. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960396/

Horse Tendon

Dakin, S. G., Smith, R. K. W., Heinegård, D., & ... (2014). Proteomic Analysis of Tendon Extracellular Matrix Reveals Disease Stage-specific Fragmentation and Differential Cleavage of COMP (Cartilage Oligomeric Matrix Protein). Journal of Biological Chemistry 289, 4919 – 4927. Retrieved from http://www.jbc.org/content/289/8/4919.short

Human Prostatic Epithelial Cells

Damodarasamy, M., & Vernon, R. (2014). Hyaluronan in aged collagen matrix increases prostate epithelial cell proliferation. In Vitro Cellular & Dev. Biol. – Animal doi: 10.1007/s11626-014-9800-z. Retrieved from http://link.springer.com/article/10.1007/s11626-014-9800-z

Rat Left Ventricle

Daryadel, A., & Bogdanova, A. (2014). Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway. Journal of Cardiothoracic Surgery 9, 81. Retrieved from http://www.biomedcentral.com/content/pdf/1749-8090-9-81.pdf

Human Lung Extracts

Das, S., Kumar, M., & Negi, V. (2014). MicroRNA-326 Regulates Profibrotic Functions of Transforming Growth Factor-β in Pulmonary Fibrosis. American Journal of Respiratory, Cell and Molecular Biology 50, 882 – 892. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0195OC

Human Hepatic Stellate Cell Line (LX-2)

den Hartog, G. J. M., Qi, S., van Tilburg, J. H. O., & ... (2014). Superoxide anion radicals activate hepatic stellate cells after entry through chloride channels: A new target in liver fibrosis. European Journal of Pharmacology 724, 140 – 144. Retrieved from http://www.sciencedirect.com/science/article/pii/S0014299913009618

Rat Cardiac Fibroblasts

Driesen, R. B., Nagaraju, C. K., & ... (2014). Reversible and irreversible differentiation of cardiac fibroblasts. Cardiovascular Research 101, 411 – 422. Retrieved from http://cardiovascres.oxfordjournals.org/content/101/3/411.short

Mouse Lung and Dendritic Cells

Dunand-Sauthier, I., Irla, M., Carnesecchi, S., & ... (2014). Repression of Arginase-2 Expression in Dendritic Cells by MicroRNA-155 Is Critical for Promoting T Cell Proliferation. The Journal of Immunology 193, 1690 – 1700. Retrieved from http://www.jimmunol.org/content/193/4/1690.short

Mouse Skeletal and Cardiac Muscle

Ermolova, N., Martinez, L., & Vetrone, S. (2014). Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function. Neuromuscular Disorders 24, 583 – 595. Retrieved from http://www.sciencedirect.com/science/article/pii/S0960896614001084

Mouse Liver

Espíndola, M., & Frantz, F. (2014). Combined immunization using DNA-Sm14 and DNA-Hsp65 increases CD8+ memory T cells, reduces chronic pathology and decreases egg viability during Schistosoma mansoni infection. BMC Infectious Diseases 14, 263. Retrieved from http://www.biomedcentral.com/1471-2334/14/263

Basement Membrane Complex of Porcine Urinary Bladder

Faulk, D. M., Carruthers, C. A., Warner, H. J., Kramer, C. R., & ... (2014). The effect of detergents on the basement membrane complex of a biologic scaffold material. Acta Biomaterialia 10, 183 – 193. Retrieved from http://www.sciencedirect.com/science/article/pii/S1742706113004595

Mouse Colon

Fichtner-Feigl, S., Kesselring, R., Martin, M., & ... (2014). IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β. The Journal of Immunology 192, 3969 – 3980. Retrieved from http://www.jimmunol.org/content/192/8/3969.short

Murine Lung

François, A., Gombault, A., & Villeret, B. (2014). B cell activating factor is central to bleomycin-and IL-17-mediated experimental pulmonary fibrosis. Journal of Autoimmunity doi: 10.1016/j.jaut.2014.08.003. Retrieved from http://www.sciencedirect.com/science/article/pii/S0896841114001280

Mouse Model of Urogenital Schistosomiasis

Fu, C., Odegaard, J., & Hsieh, M. (2014). Macrophages are required for host survival in experimental urogenital schistosomiasis. The FASEB Journal doi: 10.1096/fj.14-259572. Retrieved from http://www.fasebj.org/content/early/2014/10/27/fj.14-259572.abstract

Rat, Skin and Lung

Gao, F., Fish, B. L., Szabo, A., Schock, A., & ... (2014). Enhanced survival from radiation pneumonitis by combined irradiation to the skin. International Journal of Radiation Biology 90, 753 – 761. Retrieved from http://informahealthcare.com/doi/abs/10.3109/09553002.2014.922722

Rat Lung

Gazdhar, A., Grad, I., & Tamò, L. (2014). The secretome of induced pluripotent stem cells reduces lung fibrosis in part by hepatocyte growth factor. Stem Cell Research & Therapy 5, 123. Retrieved from http://stemcellres.com/content/5/6/123/abstract

Osteoblasts and Osteoclasts

Ghag, A. K., Gough, J. E., & Downes, S. (2014). The osteoblast and osteoclast responses to phosphonic acid containing poly (ε-caprolactone) electrospun scaffolds. Biomaterials Science 2, 233 – 241. Retrieved from http://pubs.rsc.org/EN/content/articlehtml/2014/bm/c3bm60188a

Mouse Lung

Gharib, S. A., Johnston, L. K., Huizar, I., & ... (2014). MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis. Journal of Leukocyte Biology 95, 9 – 18. Retrieved from http://www.jleukbio.org/content/95/1/9.short

Human and Porcine Lungs

Gilpin, S. E., Guyette, J. P., Gonzalez, G., Ren, X., & ... (2014). Perfusion decellularization of human and porcine lungs: Bringing the matrix to clinical scale. The Journal of Heart and Lung Transplantation 33, 298 – 308. Retrieved from http://www.sciencedirect.com/science/article/pii/S1053249813015118

Mouse Lung

Glista-Baker, E. E., Taylor, A. J., & ... (2014). Nickel Nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet). Particle and Fibre Toxicology 11, 7. Retrieved from http://www.particleandfibretoxicology.com/content/11/1/7/abstract

Rat Aorta

Gu, Q., Wang, B., Zhang, X. F., Ma, Y. P., Liu, J. D., & ... (2014). Chronic aerobic exercise training attenuates aortic stiffening and endothelial dysfunction through preserving aortic mitochondrial function in aged rats. Experimental Gerontology 56, 37 – 44. Retrieved from http://www.sciencedirect.com/science/article/pii/S0531556514000710

Rat Lung

Gustafsson, Å., Svensson‐Elfsmark, L., & ... (2014). Strain differences influence timing and magnitude of both acute and late inflammatory reactions after intratracheal instillation of an alkylating agent in rats. Journal of Applied Toxicology 34, 272 – 280. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jat.2878/full

Porcine Aortic Valve Leaflets

Hammer, P. E., Pacak, C. A., Howe, R. D., & del Nido, P. J. (2014). Straightening of curved pattern of collagen fibers under load controls aortic valve shape. Journal of Biomechanics 47, 341 – 346. Retrieved from http://www.sciencedirect.com/science/article/pii/S002192901300585X

Mouse Lung

Hams, E., Armstrong, M. E., Barlow, J. L., & ... (2014). IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proceedings of the Natl Acad Sci. 111, 367 – 372. Retrieved from http://www.pnas.org/content/111/1/367.short

Primary Human Osteoblasts

Henstock, J. R., Ruktanonchai, U. R., Canham, L. T., & ... (2014). Porous silicon confers bioactivity to polycaprolactone composites in vitro. Journal of Materials Science 25, 1087 – 1097. Retrieved from http://link.springer.com/article/10.1007/s10856-014-5140-5

Human Dermal Fibroblasts and Melanocytes

Ho, M., Koh, D., & Cho, M. (2014). The mixture of glycitin and TDB (3-(2, 4, 6-trimethoxyphenyl)-2, 3-dihydro-1H-benzo[f]chromen-1-one) could ameliorate skin ageing by anti-wrinkle and anti-melanogenesis effects in dermal fibroblasts and melanocytes. Journal of the Korean Society for Applied Biological Chemistry 57, 835 – 842. Retrieved from http://link.springer.com/article/10.1007/s13765-014-4304-9

Human Hepatic Stellate Cells

Hodge, A., Lourensz, D., Vaghjiani, V., Nguyen, H., & ... (2014). Soluble factors derived from human amniotic epithelial cells suppress collagen production in human hepatic stellate cells. Cytotherapy 16, 1132 – 1144. Retrieved from http://www.sciencedirect.com/science/article/pii/S1465324914000255

Parietal Epithelial Cells/Bowman’s Capsule

Holderied, A., Romoli, S., & Eberhard, J. (2014). Glomerular parietal epithelial cell activation induces collagen secretion and thickening of Bowman’s capsule in diabetes. Laboratory Investigation doi: 10.1038/labinvest.2014.160. Retrieved from http://www.nature.com/articles/labinvest2014160

Mouse Intestine

Holzscheiter, M., Layland, L. E., & ... (2014). Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis. Clinical & Experimental Immunology 175, 246 – 257. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/cei.12230/full

Mouse Lung

Hong, G., Kim, N., Kim, T., & Ro, J. (2014). CD1d expressed in mast cell surface enhances IgE production in B cells by up-regulating CD40L expression and mediator release in allergic asthma in mice. Cellular Signalling 26, 1105 – 1117. Retrieved from http://www.sciencedirect.com/science/article/pii/S0898656814000564

Mouse Lung

Hong, G. U., Kim, N. G., & Ro, J. Y. (2014). Expression of Airway Remodeling Proteins in Mast Cell Activated by TGF-β Released in OVA-Induced Allergic Responses and Their Inhibition by Low-Dose Irradiation or 8-oxo-dG. Radiation Research 181, 425 – 438. Retrieved from http://www.rrjournal.org/doi/abs/10.1667/RR13547.1

Human Intestinal Subepithelial Myofibroblasts (ISEMFs)

Honzawa, Y., Nakase, H., Shiokawa, M., Yoshino, T., & ... (2014). Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn’s disease. Gut doi: 10.1136/gutjnl-2013-305632. Retrieved from http://gut.bmj.com/content/early/2014/02/17/gutjnl-2013-305632.full?g=widget_default

Primary Human Lung Myofibroblasts

Hostettler, K. (2014). Nintedanib (BIBF 1120) prevents TGF-β-induced pro-fibrotic effects in primary human lung myofibroblasts derived from patients with idiopathic pulmonary fibrosis. European Respiratory Journal 44, Suppl 58 p746. Retrieved from http://erj.ersjournals.com/content/44/Suppl_58/P746.short

Human Lung Fibroblasts

Hostettler, K., & Zhong, J. (2014). Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis. Respiratory Research 15, 157. Retrieved from http://www.biomedcentral.com/content/pdf/s12931-014-0157-3.pdf

Mouse Lung

House, J., Li, H., DeGraff, L., & Flake, G. (2014). Genetic variation in HTR4 and lung function: GWAS follow-up in mouse. The FASEB Journal doi:10.1096/fj.14-253898. Retrieved from http://www.fasebj.org/content/early/2014/10/23/fj.14-253898.abstract

Rat Lung

Huang, L., Chou, H., Lin, C., Yeh, T., & Chen, C. (2014). Maternal Nicotine Exposure Exacerbates Neonatal Hyperoxia-Induced Lung Fibrosis in Rats. Neonatology 106, 94 – 101.

Polydimethylsiloxane-Modified Chitosan (PMSc) Amphiphilic Hydrogel

Huang, W. C., Liu, K. H., Liu, T. C., Liu, D. M., & Chen, S. Y. (2014). Synergistic hierarchical silicone-modified polysaccharide hybrid as a soft scaffold to control cell adhesion and proliferation. Acta Biomaterialia 10, 3546 – 3556. Retrieved from http://www.sciencedirect.com/science/article/pii/S1742706114001949

Rabbit Ear and Fibroblasts

Huang, Y., Huang, C., Hu, C., & Wong, T. (2014). Portable ultraviolet light A1 light source to treat hypertrophic scar. Dermatologica Sinica doi: 10.1016/j.dsi.2014.10.001. Retrieved from http://www.sciencedirect.com/science/article/pii/S1027811714000573

Rabbit Subchondral Bone Mesenchymal Stem Cells

Huh, J., Koh, P., Seo, B., & Park, Y. (2014). Mangiferin Reduces the Inhibition of Chondrogenic Differentiation by IL-1β in Mesenchymal Stem Cells from Subchondral Bone and Targets Multiple Aspects. International Journal of Mol Sci 15, 16025 – 16042. Retrieved from http://www.mdpi.com/1422-0067/15/9/16025/htm

Mouse Lung

Inomata, M., Kamio, K., & Azuma, A. (2014). Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis. Respiratory Research 15, 16. Retrieved from http://www.biomedcentral.com/content/pdf/1465-9921-15-16.pdf

Rat Arteries and Veins

Jelinic, M., Leo, C. H., Uiterweer, E. D. P., Sandow, S. L., & ... (2014). Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment. The FASEB Journal 28, 275 – 287. Retrieved from http://www.fasebj.org/content/28/1/275.short

Rat Kidney

Jiang, G. T., Chen, X., Li, D., An, H. X., & ... (2014). Ulinastatin attenuates renal interstitial inflammation and inhibits fibrosis progression in rats under unilateral ureteral obstruction. Molecular Medicine Reports 10, 1501 – 1508. Retrieved from http://www.spandidos-publications.com/mmr/10/3/1501

Goat Dermis Isolated Adult Stem Cells (DIAs)

Kalpakci, K., Brown, W., Hu, J., & Athanasiou, K. (2014). Cartilage Tissue Engineering Using Dermis Isolated Adult Stem Cells: The Use of Hypoxia during Expansion versus Chondrogenic Differentiation. PloS One 9, e98570. Retrieved from http://dx.plos.org/10.1371/journal.pone.0098570

Human Nasal Polyp-Derived Fibroblasts

Kang, J. S., Park, I. H., Cho, J. S., Hong, S. M., & ... (2014). Epigallocatechin‐3‐Gallate Inhibits Collagen Production of Nasal Polyp‐Derived Fibroblasts. Phytotherapy Research 28, 98 – 103. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/ptr.4971/full

Myofibroblast Cells

Kang, Y. M., Choi, Y. R., Yun, C. O., Park, J. O., & ... (2014). Down‐regulation of collagen synthesis and matrix metalloproteinase expression in myofibroblasts from dupuytren nodule using adenovirus‐mediated relaxin gene therapy. Journal of Orthopaedic Research 32, 515 – 523. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jor.22535/full

Mouse Lung

Kang, Y. Y., Kim, D. Y., Lee, S. H., & Choi, E. Y. (2014). Deficiency of developmental endothelial locus-1 (Del-1) aggravates bleomycin-induced pulmonary fibrosis in mice. Biochemical and Biophysical Research Communications 445, 369 – 374. Retrieved from http://www.sciencedirect.com/science/article/pii/S0006291X14002526

Primary Human Dermal Fibroblasts

Kanji, S., Das, M., & Aggarwal, R. (2014). Nanofiber‐expanded human umbilical cord blood–derived CD34+ cell therapy accelerates cutaneous wound closure in NOD/SCID mice. Journal of Cellular and Molecular Medicine 18, 685 – 697. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/jcmm.12217/full

Mouse Renal Tissue

Kanno, Y., Kawashita, E., & Kokado, A. (2014). 2AP mediated myofibroblast formation and the development of renal fibrosis in unilateral ureteral obstruction. Scientific Reports 4, Article Number: 5967.Retrieved from http://www.nature.com/srep/2014/140806/srep05967/full/srep05967.html

Mouse Lung

Karmouty-Quintana, H., Philip, K., & Acero, L. (2014). Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension. The FASEB Journal doi: 10.1096/fj.14-260182. Retrieved from http://www.fasebj.org/content/early/2014/10/09/fj.14-260182.abstract

Human Lung Fibroblasts

Kasabova, M., Joulin-Giet, A., Lecaille, F., & ... (2014). Regulation of TGF-β1-driven Differentiation of Human Lung Fibroblasts EMERGING ROLES OF CATHEPSIN B AND CYSTATIN C. Journal of Biological Chemistry 289, 16329 – 16251. Retrieved from http://www.jbc.org/content/289/23/16239.short

Human Fibroblasts

Kawalec, M., & Sitkowska, A. (2014). Human procollagen type I surface-modified PHB-based non-woven textile scaffolds for cell growth: preparation and short-term biological tests. Biomedical Materials 9, 065005. Retrieved from http://iopscience.iop.org/1748-605X/9/6/065005

Human Mesenchymal Stromal Cells

Khan, M., Donos, N., Salih, V., & Brett, P. (2014). Receptor Kinase AXL is Modulated in the Osteogenic Differentiation of Human Mesenchymal Stromal Cells on Modified Titanium Implant Surfaces. J Stem Cell Res Ther. 4, 9. Retrieved from http://omicsonline.org/open-access/receptor-kinase-axl-is-modulated-in-the-osteogenic-differentiation-of-human-mesenchymal-stromal-cells-on-modified-titanium-implant-surfaces-2157-7633.1000233.pdf

Human Collagen Based Multilayer Scaffolds

Kim, B. S., Kim, E. J., Choi, J. S., & ... (2014). Human collagen‐based multilayer scaffolds for tendon‐to‐bone interface tissue engineering. Journal of Biomedical Materials Research Part A 102, 4044 – 4054. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.35057/full

Human Hepatic Stellate Cells (LX-2) and Rat Primary Hepatic Stellate Cells

Kim, J. H., Jeong, Y. J., Hong, J. M., Kim, H. R., Kang, J. S., & ... (2014). Chronic vitamin C insufficiency aggravated thioacetamide-induced liver fibrosis in gulo-knockout mice. Free Radical Biology Medicine 67, 81 – 90. Retrieved from http://www.sciencedirect.com/science/article/pii/S0891584913014809

Rat Liver Extract

Kim, M., Kim, S., & Cha, H. (2014). Therapeutic effect of hepatocyte growth factor-secreting mesenchymal stem cells in a rat model of liver fibrosis. Experimental & Molecular Medicine 46, e110. Retrieved from http://www.nature.com/emm/journal/v46/n8/abs/emm201449a.html

Mouse Osteoblast Cells (MC3T3-E1_

Kim, S., Shin, M., Son, K., & Sohn, H. (2014). Yam (Dioscorea batatas) Root and Bark Extracts Stimulate Osteoblast Mineralization by Increasing Ca and P Accumulation and Alkaline Phosphatase Activity. Preventive Nutrition and Food Science 19, 194 – 203. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195625/

Preosteoblasts and Human Mesenchymal Stem Cells

Kwon, B. J., Lee, M. H., Koo, M. A., Han, J. J., & ... (2014). Ethyl-3, 4-dihydroxybenzoate with a dual function of induction of osteogenic differentiation and inhibition of osteoclast differentiation for bone tissue engineering. Tissue Engineering Part A, doi:10.1089/ten.tea.2013.0567. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.TEA.2013.0567

Mouse Lung

Lam, A., & Herazo-Maya, J. (2014). Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 190, 185 – 195. Retrieved from http://www.atsjournals.org/doi/abs/10.1164/rccm.201401-0079OC

Mouse Lung

Le, T., & Karmouty-Quintana, H. (2014). Blockade of IL-6 Trans Signaling Attenuates Pulmonary Fibrosis. The Journal of Immunology 193, 3755 – 3768. Retrieved from http://www.jimmunol.org/content/193/7/3755.short

Mouse Lung

Lee, M. R., Lee, G. H., Lee, H. Y., Kim, D. S., Chung, M. J., & ... (2014). BAX inhibitor-1-associated V-ATPase glycosylation enhances collagen degradation in pulmonary fibrosis. Cell Death & Disease 5, e1113. Retrieved from http://www.nature.com/cddis/journal/v5/n3/abs/cddis201486a.html

Mouse Lung

Lee, R., Reese, C., Bonner, M., Tourkina, E., & ... (2014). Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease. American Journal of Physiology – Lung Cellular and Molecular Physiology 306, L736 – L748. Retrieved from http://ajplung.physiology.org/content/306/8/L736.abstract

Primary Chondrocytes

Lee, S. Y., & Kamarul, T. (2014). NO, carboxymethyl chitosan enhanced scaffold porosity and biocompatibility under e-beam irradiation at 50kGy. International Journal of Biological Macromolecules 64, 115 – 122. Retrieved from http://www.sciencedirect.com/science/article/pii/S0141813013006491

Mouse Lung

Li, D., Guabiraba, R., & Besnard, A. (2014). IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice. Journal of Allergy and Clinical Immunology doi: 10.1016/j.jaci.2014.05-011. Retrieved from http://www.sciencedirect.com/science/article/pii/S0091674914006708

Osteoblasts

Li, H., Zhu, R., Sun, L., Xue, Y., Hao, Z., Xie, Z., & ... (2014). Effect of Thickness of HA-Coating on Microporous Silk Scaffolds Using Alternate Soaking Technology. BioMed Research International Article ID 637821, 8 pages. Retrieved from http://www.hindawi.com/journals/bmri/2014/637821/abs/

Mouse Lung

Li, L. F., Liu, Y. Y., Kao, K. C., Wu, C. T., Chang, C. H., & ... (2014). Mechanical ventilation augments bleomycin-induced epithelial–mesenchymal transition through the Src pathway. Laboratory Investigation 94, 1017 – 1029. Retrieved from http://www.nature.com/labinvest/journal/vaop/ncurrent/full/labinvest201475a.html

Rat Renal Fibroblasts (NRK-49F)

Li, L., Shen, Y., Ding, Y., Liu, Y., Su, D., & Liang, X. (2014). Hrd1 participates in the regulation of collagen I synthesis in renal fibrosis. Molecular and Cellular Biochem 386, 35 – 44. Retrieved from http://link.springer.com/article/10.1007/s11010-013-1843-z

Animal Lung

Li, R., Ji, Z., Chang, C., Dunphy, D., & Cai, X. (2014). Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design. ACS Nano 8, 1771 – 1783. Retrieved from http://pubs.acs.org/doi/abs/10.1021/nn406166n

Mouse Lung

Liang, H., Xu, C., Pan, Z., Zhang, Y., Xu, Z., Chen, Y., … (2014). The Antifibrotic Effects and Mechanisms of MicroRNA-26a Action in Idiopathic Pulmonary Fibrosis. Molecular Therapy doi: 10.1038/mt.2014.42. Retrieved from http://www.nature.com/mt/journal/vaop/ncurrent/full/mt201442a.html

Human Dermal Fibroblasts and Mouse Model of Systemic Sclerosis (SSc)

Liang, M., Lv, J., Chu, H., Wang, J., & Chen, X. (2014). Vertical Inhibition of PI3K/Akt/mTOR Signaling Demonstrates In vitro and In vivo Anti-fibrotic Activity. Journal of Dermatological Science 76, 104 – 111. Retrieved from http://www.sciencedirect.com/science/article/pii/S0923181114001868

Mouse Skin and Lung

Liang, M., Lv, J., Zou, L., Yang, W., & Xiong, Y. (2014). A modified murine model of systemic sclerosis: bleomycin given by pump infusion induced skin and pulmonary inflammation and fibrosis. Laboratory Investigation doi: 10.1038/labinvest.2014.145. Retrieved from http://www.nature.com/labinvest/journal/vaop/ncurrent/full/labinvest2014145a.html

Mouse Lung

Lin, C. C., Lin, L. J., Wang, S. D., Chiang, C. J., & ... (2014). The Effect of Serine Protease Inhibitors on Airway Inflammation in a Chronic Allergen-Induced Asthma Mouse Model. Mediators of Inflammation Article ID 879326, 10 pages. Retrieved from http://www.hindawi.com/journals/mi/2014/879326/abs/

Murine Fibrosarcoma Cell Line (L929)

Lin, H. Y., Peng, C. W., & Wu, W. W. (2014). Fibrous hydrogel scaffolds with cells embedded in the fibers as a potential tissue scaffold for skin repair. Journal of Materials Science: Materials in Medicine 25, 259 – 269. Retrieved from http://link.springer.com/article/10.1007/s10856-013-5065-4

Mouse Lung and Zebrafish Gastrointestinal Tract

Lin, S., Wang, X., Ji, Z., Chang, C. H., Dong, Y., Meng, H., & ... (2014). Aspect Ratio Plays a Role in the Hazard Potential of CeO2 Nanoparticles in Mice Lung and Zebrafish Gastrointestinal Tract. ACS Nano 8, 4450 – 4464. Retrieved from http://pubs.acs.org/doi/abs/10.1021/nn5012754

Murine Lung

Liu, F., Lagares, D., & Choi, K. (2014). Mechanosignaling through YAP and TAZ drive fibroblast activation and fibrosis. American Journal of Physiology Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00300.2014. Retrieved from http://ajplung.physiology.org/content/early/2014/12/09/ajplung.00300.2014.abstract

Rabbit Bone Marrow and Synovium-Derived MSCs

Liu, H., Wei, X., Ding, X., Li, X., Zhou, G., & ... (2014). Comparison of cellular responses of mesenchymal stem cells derived from bone marrow and synovium on combined silk scaffolds. Journal of Biomedical Materials Research Part A doi: 10.1002/jbm.a.35154. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.35154/full

Rat Lung

Liu, M., Su, M., Wei, Z., & Yan-qiong, W. (2014). Protective effect of Xuebijing injection on paraquat-induced pulmonary injury via down-regulating the expression of p38 MAPK in rats. BMC Complementary & Alternative Medicine 14, 498. Retrieved from http://www.biomedcentral.com/1472-6882/14/498/

Mouse Left Ventricular Myocardium

Lodder, E., & Scicluna, B. (2014). An Integrative Genomic Approach Identifies Multiple Genes Involved in Cardiac Collagen Deposition. Circulation: Cardiovascular Genetics doi: 10.1161/CIRCGENETICS.114-000537. Retrieved from http://circgenetics.ahajournals.org/content/early/2014/09/12/CIRCGENETICS.114.000537.short

Decellularised Adipose Tissue

Lu, Q., Li, M., Zou, Y., & Cao, T. (2014). Delivery of basic fibroblast growth factors from heparinized decellularized adipose tissue stimulates potent de novo adipogenesis. Journal of Controlled Release 174, 43 – 50. Retrieved from http://www.sciencedirect.com/science/article/pii/S0168365913008961

Primary Human Lung Fibroblasts

Luanpitpong, S., Wang, L., & Manke, A. (2014). Induction of Stem-Like Cells with Fibrogenic Properties by Carbon Nanotubes and Its Role in Fibrogenesis. Nano Letters 14, 3110 – 3116. Retrieved from http://pubs.acs.org/doi/abs/10.1021/nl5002026

Fibrocartilaginous Neotissues

MacBarb, R. F., Paschos, N. K., Abeug, R., & ... (2014). Passive strain-induced matrix synthesis and organization in shape-specific, cartilaginous neotissues. Tissue Engineering Part A doi: 10.1089/ten.tea.2013.0694. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.TEA.2013.0694

Mouse Lung

Madala, S. K., Korfhagen, T. R., Schmidt, S., & ... (2014). Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis. American Journal of Physiology – Lung Cellular and Molecular Physiology 306, L726 – L735. Retrieved from http://ajplung.physiology.org/content/306/8/L726.abstract

Mouse Lung

Maduekwe, E. T., Buczynski, B. W., Yee, M., & ... (2014). Cumulative neonatal oxygen exposure predicts response of adult mice infected with influenza A virus. Pediatric Pulmonary doi: 10.1002/ppul.23063. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/ppul.23063/full

Human Gingival Fibroblasts

Mah, W., Jiang, G., Olver, D., Cheung, G., Kim, B., Larjava, H., & ... (2014). Human Gingival Fibroblasts Display a Non-Fibrotic Phenotype Distinct from Skin Fibroblasts in Three-Dimensional Cultures. PloS One 9, e90715.

Neo Fibrocartilage Implant

Makris, E. A., MacBarb, R. F., Paschos, N. K., Hu, J. C., & ... (2014). Combined use of chondroitinase-ABC, TGF-β1, and collagen crosslinking agent lysyl oxidase to engineer functional neotissues for fibrocartilage repair. Biomaterials 35, 6787 – 6796. Retrieved from http://www.sciencedirect.com/science/article/pii/S0142961214004815

Human Lung Fibroblasts

Manke, A., Luanpitpong, S., & Dong, C. (2014). Effect of Fiber Length on Carbon Nanotube-Induced Fibrogenesis. International Journal of Mol. Sci. 15, 7444 – 7461. Retrieved from http://www.mdpi.com/1422-0067/15/5/7444/pdf

Valvular Interstitial Cells and MSCs on Tissue Engineered Heart Valves

Masoumi, N., Annabi, N., Assmann, A., Larson, B. L., & ... (2014). Tri-layered elastomeric scaffolds for engineering heart valve leaflets. Biomaterials 35, 7774 – 7785. Retrieved from http://www.sciencedirect.com/science/article/pii/S0142961214004372

Human Limbal Fibroblasts

Massie, I., Dale, S., & Daniels, J. (2014). Limbal fibroblasts maintain normal phenotype in 3D RAFT tissue equivalents suggesting potential for safe clinical use in treatment of ocular surface failure. Tissue Engineering Part C: Methods doi: 10.1089/ten.tec.2014.0458. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.TEC.2014.0458

Porcine Heart

Methe, K., & Bäckdahl, H. (2014). An Alternative Approach to Decellularize Whole Porcine Heart. BioResearch Open Access doi: 10.1089/biores.2014.0046. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/biores.2014.0046

Mouse Lung

Miller, M., Rosenthal, P., Beppu, A., & ... (2014). ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma. The Journal of Immunology 192, 3475 – 3487. Retrieved from http://www.jimmunol.org/content/192/8/3475.short

Bronchoalveolar Lavage Fluid and Lung Tissue

Mi, S., Li, Z., Yang, H., & Liu, H. (2014). Correction: Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF-β1–Dependent and–Independent Mechanisms. The Journal of Immunology 193, 5345 – 5346. Retrieved from http://www.jimmunol.org/content/193/10/5345.short

Human Dermal Fibroblast Cells

Mohamed, M. A. A., Jung, M., Lee, S. M., Lee, T. H., & ... (2014). Protective effect of Disporum sessile D. Don extract against UVB-induced photoaging via suppressing MMP-1 expression and collagen degradation in human skin cells. Journal of Photochemistry and Photobiology B. Biology 135, 73 – 79. Retrieved from http://www.sciencedirect.com/science/article/pii/S1011134414000669

Mouse Lung

Monnier, J., & Zabel, B. (2014a). Anti-Asialo GM1 NK Cell Depleting Antibody Does Not Alter the Development of Bleomycin Induced Pulmonary Fibrosis. PloS One 9, e99350. Retrieved from http://dx.plos.org/10.1371/journal.pone.0099350

Mouse Lung

Moshai, E. F., Wémeau-Stervinou, L., & ... (2014). Targeting the Hedgehog-Gli Pathway Inhibits Bleomycin-Induced Lung Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology 51, 11 – 25. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0154OC

Mouse Lung

Murdoch, J. (2014). γδT cells regulate chronic airway inflammation and development of airway remodelling. Clinical & Experimental Allergy 44, 1386 – 1398. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/cea.12395/full

Porcine Aortic Valve Leaflets

Myles, V., Liao, J., & Warnock, J. (2014). Cyclic Pressure and Angiotensin II Influence the Biomechanical Properties of Aortic Valves. Journal of Biomechanical Engineering 136, 011011. Retrieved from http://mechanicaldesign.asmedigitalcollection.asme.org/article.aspx?articleid=1779389

Human Lung Adenocarcinoma Cells (A549)

Nakajima, F., & Aratani, S. (2014). Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia. International Journal of Molecular Medicine doi: 10.3892/ijmm.2014.1984. Retrieved from http://www.spandidos-publications.com/10.3892/ijmm.2014.1984

Human Bone Marrow-Derived Mesenchymal Stromal Cells

Nam, H., & Pingguan-Murphy, B. (2014). The proliferation and tenogenic differentiation potential of bone marrow-derived mesenchymal stromal cell are influenced by specific uniaxial cyclic tensile loading conditions. Biomech. Model Mechanobiol doi: 10.1007/s10237-014-0628-y. Retrieved from http://link.springer.com/article/10.1007/s10237-014-0628-y

Normal Human Dermal Fibroblasts

Nazaruk, J., & Galicka, A. (2014). The Influence of Selected Flavonoids from the Leaves of Cirsium palustre (L.) Scop. on Collagen Expression in Human Skin Fibroblasts. Phytotherapy Research 28, 1399 – 1405. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/ptr.5143/full

Mouse Lung

Noguchi, S., Yatera, K., & Wang, K. (2014). Nitric oxide exerts protective effects against bleomycin-induced pulmonary fibrosis in mice. Respiratory Research 15, 92. Retrieved from http://www.biomedcentral.com/content/pdf/s12931-014-0092-3.pdf

Mouse Lung

Ogawa, H., Ledford, J., & Mukherjee, S. (2014). Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β. Respiratory Research 15, 143. Retrieved from http://www.biomedcentral.com/content/pdf/s12931-014-0143-9.pdf

Lung Tissue

Ono, M., Ohkouchi, S., & Kanehira, M. (2014). Mesenchymal Stem Cells Correct Inappropriate Epithelial–mesenchyme Relation in Pulmonary Fibrosis Using Stanniocalcin-1. Molecular Therapy doi: 10.1038/mt.2014.217. Retrieved from http://www.nature.com/mt/journal/vaop/ncurrent/full/mt2014217a.html

Human Vertebral Bone Marrow Cells

Park, D., Park, J., & Lee, J. (2014). Effect of FGF-2 on collagen tissue regeneration by human vertebral bone marrow stem cells. Stem Cells and Development doi: 10.1089/scd.2014.0148. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/scd.2014.0148

Mouse Liver

Park, S. L., Lee, S. Y., Nam, Y. D., Yi, S. H., Seo, M. J., & ... (2014). Hepatoprotective effect of fermented rice bran against carbon tetrachloride-induced toxicity in mice. Food Science and Biotechnol. 23, 165 – 171. Retrieved from http://link.springer.com/article/10.1007/s10068-014-0022-7

Human Bone Marrow Stem Cells and Human Periodontal Ligament Stem Cells

Park, S., Park, J., & Kim, M. (2014). Differential Effect of Water-Soluble Chitin on Collagen Synthesis of Human Bone Marrow Stem Cells and Human Periodontal Ligament Stem Cells. Tissue Engineering Part A doi: 10.1089/ten.tea.2014.0156. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.tea.2014.0156

Bovine Ankles and Bovine Ankle Chondrocytes

Paschos, N. K., Makris, E. A., Hu, J. C., & ... (2014). Topographic Variations in Biomechanical and Biochemical Properties in the Ankle Joint: An In Vitro Bovine Study Evaluating Native and Engineered Cartilage. Arthroscopy: The Journal of Arthroscopic and Related Surgery 30, 1317 – 1326. Retrieved from http://www.sciencedirect.com/science/article/pii/S0749806314004836

Human Trabecular Meshwork Cells

Pattabiraman, P. (2014). Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling. Journal of Cellular Physiology 229, 927 – 942. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jcp.24524/full

Rat Lung

Pauluhn, J. (2014). Repeated inhalation exposure of rats to an anionic high molecular weight polymer aerosol: Application of prediction models to better understand pulmonary effects and modes of action. Experimental and Toxicologic Pathology 66, 243 – 256. Retrieved from http://www.sciencedirect.com/science/article/pii/S0940299314000451

Murine Lung

Peng, X., Moore, M., Peng, H., & Sun, H. (2014). CD4+ CD25+ FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung. Frontiers in Pharmacology 5, 80. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032896/

Mouse Skin and Internal Organs

Pérez‐Frías, A. (2014). Development of an Autoimmune Syndrome Affecting the Skin and Internal Organs in P‐Selectin Glycoprotein Ligand 1 Leukocyte Receptor–Deficient Mice. Arthritis & Rheumatology 66, 3178 – 3189. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/art.38808/full

Mouse Skin and Internal Organs

Pérez‐Frías, A., González‐Tajuelo, R., & ... (2014). P‐selectin glycoprotein ligand‐1 leukocyte receptor deficiency in mice induces an autoimmune syndrome affecting the skin and internal organs. Arthritis & Rheumatology doi: 10.1002/art.38808. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/art.38808/abstract

Normal Human Dermal Fibroblasts (NHDF)

Phetpornpaisan, P., Tippayawat, P., Jay, M., & ... (2014). A local Thai cultivar glutinous black rice bran: A source of functional compounds in immunomodulation, cell viability and collagen synthesis, and matrix metalloproteinase-2 and -9 inhibition. Journal of Functional Foods 7, 650 – 661. Retrieved from http://www.sciencedirect.com/science/article/pii/S1756464613003149

Bovine Anterior Mitral Valve Leaflets

Pierlot, C. M., Lee, J. M., Amini, R., Sacks, M. S., & ... (2014). Pregnancy-Induced Remodeling of Collagen Architecture and Content in the Mitral Valve. Annals of Biomedical Engineering 40, 2058 – 2071. Retrieved from http://link.springer.com/article/10.1007/s10439-014-1077-6

Mouse Lung

Pilling, D., & Gomer, R. (2014). Persistent Lung Inflammation and Fibrosis in Serum Amyloid P Component (Apcs-/-) Knockout Mice. PloS One 9, e93730. Retrieved from http://dx.plos.org/10.1371/journal.pone.0093730.g011

Mouse Cardiac tissue and Cardiac Fibroblasts

Qin, W., Du, N., Zhang, L., Wu, X., & Hu, Y. (2014). Genistein alleviates pressure overload‐induced cardiac dysfunction and interstitial fibrosis in mice. British Journal of Pharmacology doi: 10.1111/bph.13002. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/bph.13002/abstract

Human Cardiac Progenitor Cells

Rajabi-Zeleti, S., Jalili-Firoozinezhad, S., Azarnia, M., & ... (2014). The behavior of cardiac progenitor cells on macroporous pericardium-derived scaffolds. Biomaterials 35, 970 – 982. Retrieved from http://www.sciencedirect.com/science/article/pii/S0142961213012751

Mouse Lung

Ramani, M., & Bradley, W. (2014). Early Exposure to Hyperoxia or Hypoxia Adversely Impacts Cardio-Pulmonary Development. American Journal of Resp. Cell Mol. Biol. doi: 10.1165/rcmb.2013-04910c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0491OC

Bone Marrow Derived Stem Cells BMSCs)

Ramaswamy, S., Boronyak, S., & Le, T. (2014). A Novel Bioreactor for Mechanobiological Studies of Engineered Heart Valve Bioreactor for Mechanobiological Studies of Engineered Heart Valve Tissue Formation Under Pulmonary Arterial Physiological Flow Conditions. J Biomech Eng 136 (12), 121009 (14 pages). Retrieved from http://www.biomechanical.asmedigitalcollection.asme.org/article.aspx?articleid=1918227

Mouse Lung

Reber, L. L., Daubeuf, F., Pejler, G., Abrink, M., & ... (2014). Mast Cells Contribute to Bleomycin-Induced Lung Inflammation and Injury in Mice through a Chymase/Mast Cell Protease 4–Dependent Mechanism. The Journal of Immunology 192, 1847 – 1854. Retrieved from http://www.jimmunol.org/content/192/4/1847.short

Human and Mouse Alveolar Macrophages

Reddy, A., Lakshmi, S., Zhang, Y., & Reddy, R. (2014). Nitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages. The FASEB Journal 28, 5299 – 5310. Retrieved from http://www.fasebj.org/content/28/12/5299.short

Mouse Lung

Romero, F., Shah, D., & Duong, M. (2014). A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis. American Journal of Respiratory Cell and Molecular Biology doi: 10.1165/rcmb.2014-03430c. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2014-0343OC

Mouse Lung

Ronzani, C., Casset, A., & Pons, F. (2014). Exposure to multi-walled carbon nanotubes results in aggravation of airway inflammation and remodeling and in increased production of epithelium-derived innate cytokines in a mouse model of asthma. Archives of Toxicology 88, 489 – 499. Retrieved from http://link.springer.com/article/10.1007/s00204-013-1116-3

Murine Colon

Shih, D. Q., Zheng, L., Zhang, X., Zhang, H., & ... (2014). Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal Immunology 7, 1492 – 1503. Retrieved from http://www.nature.com/mi/journal/vaop/ncurrent/full/mi201437a.html

Mouse Lung, Heart and Liver

Shvedova, A., & Kisin, E. (2014). ESR evidence for in vivo formation of free radicals in tissue of mice exposed to single-walled carbon nanotubes. Free Radical Biology and Medicine 73, 154 – 165. Retrieved from http://www.sciencedirect.com/science/article/pii/S0891584914002263

Mouse Lung

Shvedova, A., & Yanamala, N. (2014). Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. American Journal of Physiology – Lung Cellular and Molecular Physiology 306, L170 – L182. Retrieved from http://ajplung.physiology.org/content/306/2/L170.short

Mouse Lung

Skurikhin, E., & Pershina, O. (2014). Modulation of Stem and Progenitor Cells and Bleomycin-Induced Pulmonary Fibrosis by Spiperone in Mice. J. Stem Cell Res. Ther. 4, 6. Retrieved from http://omicsonline.org/open-access/modulation-of-stem-and-progenitor-cells-and-bleomycininduced-pulmonary-fibrosis-by-spiperone-in-mice-2157-7633.1000210.pdf

Human Chondrocyte Cell Line (C28/12 Cells)

Steinecker-Frohnwieser, B., Weigl, L., Kullich, W., & ... (2014). The disease modifying osteoarthritis drug diacerein is able to antagonize pro inflammatory state of chondrocytes under mild mechanical stimuli. Osteoarthritis and Cartilage 22, 1044 – 1052. Retrieved from http://www.sciencedirect.com/science/article/pii/S1063458414010875

Hepatic Stellate Cells (HSC-T6)

Su, K., Hsieh, C., & Chen, Y. (2014). Taiwanese Green Propolis and Propolin G Protect the Liver from the Pathogenesis of Fibrosis via Eliminating TGF-β-Induced Smad2/3 Phosphorylation. Journal of Agricultural and Food Chemistry 62, 3192 – 3201. Retrieved from http://pubs.acs.org/doi/abs/10.1021/jf500096c

Human Mesenchymal Stem Cells

Subramony, S., Su, A., Yeager, K., & Lu, H. (2014). Combined effects of chemical priming and mechanical stimulation on mesenchymal stem cell differentiation on nanofiber scaffolds. Journal of Biomechanics 47, 2189 – 2196. Retrieved from http://www.sciencedirect.com/science/article/pii/S0021929013004703

Human Periodontal Ligament Cells

Sugii, H., Maeda, H., Tomokiyo, A., Yamamoto, N., Wada, N., & ... (2014). Effects of Activin A on the phenotypic properties of human periodontal ligament cells. Bone 66, 62 – 71. Retrieved from http://www.sciencedirect.com/science/article/pii/S8756328214001999

Human Lung Fibroblast Cell Line (HFL-1) and Human Small Airways

Sun, C., Zhu, M., Yang, Z., Pan, X., Zhang, Y., Wang, Q., & ... (2014). LL-37 secreted by epithelium promotes fibroblast collagen production: a potential mechanism of small airway remodeling in chronic obstructive pulmonary disease. Laboratory Investigation 94, 991 – 1002. Retrieved from http://www.nature.com/labinvest/journal/vaop/ncurrent/full/labinvest201486a.html

Rabbit Bone Marrow-Derived Mesenchymal Stem Cells

Sun, L., Li, H., Qu, L., Zhu, R., Fan, X., Xue, Y., … (2014). Immobilized Lentivirus Vector on Chondroitin Sulfate-Hyaluronate Acid-Silk Fibroin Hybrid Scaffold for Tissue-Engineered Ligament-Bone Junction. BioMed Research International, Article ID 816979. Retrieved from http://www.hindawi.com/journals/bmri/2014/816979/abs/

Mouse Lung

Swain, S. D., Siemsen, D. W., Pullen, R. R., & Han, S. (2014). CD4+ T Cells and IFN-γ Are Required for the Development of Pneumocystis-Associated Pulmonary Hypertension. The American Journal of Pathology 184, 483 – 493. Retrieved from http://www.sciencedirect.com/science/article/pii/S0002944013007839

Human Wharton’s Jelly Stem Cells

Tam, K., Cheyyatraviendran, S., & ... (2014). A nanoscaffold impregnated with human Wharton’s Jelly stem cells or its secretions improves healing of wounds. Journal of Cellular Biochemistry 115, 794 – 803. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jcb.24723/full

Rat Hepatic Stellate Cells

Tanaka, Y., Minomi, K., Nakashima, Y., & Ota, S. (2014). Activated hepatic stellate cells are dependent on self collagen, cleaved by membrane type 1-matrix metalloproteinase for their growth. J. Biol. Chem. 289, 20209 – 20221. Retrieved from http://glyco.jbc.org/content/jbc/early/2014/05/27/jbc.M113.544494.full.pdf

Mouse Lung

Tang, N., Zhao, Y., Feng, R., & Liu, Y. (2014). Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts. Journal of Cellular and Molecular Medicine 18, 156 – 169. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/jcmm.12178/full

Mouse Lung

Tao, B., Jin, W., Xu, J., & Liang, Z. (2014). Myeloid-specific disruption of tyrosine phosphatase shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis. The Journal of Immunology 193, 2801 – 2811. Retrieved from http://www.jimmunol.org/content/193/6/2801.short

Rodent and Human Osteoblasts

Taylor, S., Shah, M., & Orriss, I. (2014). Generation of rodent and human osteoblasts. BoneKEy Reports 3, Article No. 585, doi: 10.1038/bonekey.2014.80. Retrieved from http://www.nature.com/bonekeyreports/2014/141112/bonekey201480/full/bonekey201480.html

Mouse Skin

Tomcik, M., Palumbo-Zerr, K., & Zerr, P. (2014). S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2013-204516. Retrieved from http://ard.bmj.com/content/early/2014/04/07/annrheumdis-2013-204516.short

Mouse Lung

Tsubouchi, H., Yanagi, S., & Miura, A. (2014). Rikkunshito ameliorates cachexia associated with bleomycin-induced lung fibrosis in mice by stimulating ghrelin secretion. Nutrition Research 34, 876 – 885. Retrieved from http://www.sciencedirect.com/science/article/pii/S0271531714001651

Mouse Lung

Tsubouchi, H., Yanagi, S., Miura, A., & ... (2014). Rikkunshito ameliorates bleomycin-induced acute lung injury in a ghrelin-independent manner. American Journal of Physiology – Lung and Cellular Molecular Physiology 306, L233 – L245. Retrieved from http://ajplung.physiology.org/content/306/3/L233.short

Human Tenocytes

Tucker, R. P., Henningsson, P., & ... (2014). See-saw rocking: an in vitro model for mechanotransduction research. Journal of The Royal Society Interface 11, 20140330. Retrieved from http://rsif.royalsocietypublishing.org/content/11/97/20140330.short

Human Exfoliated Deciduous Teeth Stem Cells

Turrioni, A. P. S., Basso, F. G., Montoro, L. A., Almeida, L. F. D., & ... (2014). Phototherapy Up-regulates Dentin Matrix Proteins Expression and Synthesis by Stem Cells from Human-Exfoliated Deciduous Teeth. Journal of Dentistry 42, 1292 – 1299. Retrieved from http://www.sciencedirect.com/science/article/pii/S030057121400219X

Byssus of Chilean Mussels

Vallejos, N., González, G., Troncoso, E., & Zúñiga, R. N. (2014). Acid and Enzyme-Aided Collagen Extraction from the Byssus of Chilean Mussels (Mytilus Chilensis): Effect of Process Parameters on Extraction Performance. Food Biophysics doi: 10.1007/s11483-014-9339-2. Retrieved from http://link.springer.com/article/10.1007/s11483-014-9339-2

Mouse Lung Tissue

van der Velden, J. L. J., Hoffman, S. M., & ... (2014). Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation. American Journal of Physiology – Lung Cellular and Molecular Physiology 306, L866 – L875. Retrieved from http://ajplung.physiology.org/content/306/9/L866.abstract

Mouse Lung

Vasiliou, J. E., Lui, S., Walker, S. A., Chohan, V., Xystrakis, E., & ... (2014). Vitamin D deficiency induces Th2 skewing and eosinophilia in neonatal allergic airways disease. Allergy 69, 1380 – 1389. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/all.12465/full

Vascular Smooth Muscle Cells

Vatankhah, E., Prabhakaran, M. P., & ... (2014). Phenotypic Modulation of Smooth Muscle Cells by Chemical and Mechanical Cues of Electrospun Tecophilic/Gelatin Nanofibers. ACS Applied Materials & Interfaces 6, 4089 – 4101. Retrieved from http://pubs.acs.org/doi/abs/10.1021/am405673h

Rat Adipose-Derived Mesenchymal Stem Cells

Veronesi, F., Pagani, S., Bella, E. Della, Giavaresi, G., & ... (2014). Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells. AGE 36, 1225 – 1238. Retrieved from http://link.springer.com/article/10.1007/s11357-014-9647-y

Mouse Lung

Walters, D. M., White, K. M., Patel, U., Davis, M. J., & ... (2014). Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5). The FASEB Journal 28, 1098 – 1112. Retrieved from http://www.fasebj.org/content/28/3/1098.short

Chondrocytes

Wang, L. S., Du, C., Toh, W. S., Wan, A. C. A., Gao, S. J., & ... (2014). Modulation of chondrocyte functions and stiffness-dependent cartilage repair using an injectable enzymatically crosslinked hydrogel with tunable mechanical properties. Biomaterials 35, 2207 – 2217. Retrieved from http://www.sciencedirect.com/science/article/pii/S0142961213014361

Non-Human Primate (Rhesus macaques) Femoral and Carotid Arteries

Wang, R., Raykin, J., Li, H., Jr, R. L. G., & ... (2014). Differential mechanical response and microstructural organization between non-human primate femoral and carotid arteries. Biomechanics and Modeling in Mechanobiology 13, 1041 – 1051. Retrieved from http://link.springer.com/article/10.1007/s10237-014-0553-0

Lung Tissue

Wang, X., Ji, Z., Chang, C. H., Zhang, H., Wang, M., Liao, Y. P., & ... (2014). Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small 10, 385 – 398. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/smll.201301597/full

Bone Marrow-Derived Mesenchymal Stem Cells-Derived ECM

Wei, B., Jin, C., Xu, Y., Du, X. T., Yan, C., Tang, C., & ... (2014). Chondrogenic differentiation of marrow clots after microfracture with BMSC-derived ECM scaffold in vitro. Tissue Engineering Part A 20, 2646 – 2655. Retrieved from http://online.liebertpub.com/doi/abs/10.1089/ten.TEA.2013.0662

Mouse Lung

Weng, T., & Poth, J. (2014). Hypoxia-induced Deoxycytidine Kinase Contributes to Epithelial Proliferation in Pulmonary Fibrosis. American Journal of Resp. Crit. Care Med. doi: 10.1164/rccm.201404-07440c. Retrieved from http://www.atsjournals.org/doi/abs/10.1164/rccm.201404-0744OC

Porcine Aortic Valvular Interstitial Cells

Witt, W., Büttner, P., Jannasch, A., Matschke, K., & ... (2014). Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling. Journal of Molecular and Cell Cardiol. 74, 127 – 138. Retrieved from http://www.sciencedirect.com/science/article/pii/S0022282814001618

Human Lung Fibroblasts and Mouse Models of Lung Fibrosis

Wollin, L., Maillet, I., & Quesniaux, V. (2014). Antifibrotic and Anti-inflammatory Activity of the Tyrosine Kinase Inhibitor Nintedanib in Experimental Models of Lung Fibrosis. Journal of Pharmacology 349, 209 – 220. Retrieved from http://jpet.aspetjournals.org/content/349/2/209.short

Human Lung Fibroblasts

Wu, C. (2014a). Mechanical properties, biocompatibility, and biodegradation of cross-linked cellulose acetate-reinforced polyester composites. Carbohydrate Polymers 105, 41 – 48. Retrieved from http://www.sciencedirect.com/science/article/pii/S014486171400071X

Human Foreskin Fibroblasts

Wu, C. (2014b). Preparation, characterisation, and biocompatibility of Ganoderma lucidum fibre-based composites with polylactic acid. Composites Science and Technology 102, 1 – 9. Retrieved from http://www.sciencedirect.com/science/article/pii/S0266353814002541

Collagen-Based Biocomposites

Wu, C. (2014). Influence of modified polyester on the material properties of collagen-based biocomposites and in vitro evaluation of cytocompatibility. Materials Science and Engineering: C 48, 310 – 319. Retrieved from http://www.sciencedirect.com/science/article/pii/S092849311400811X

Human Foreskin Fibroblasts

Wu, C., Hsu, Y., & Liao, H. (2014). Characterization and biocompatibility of chestnut shell fiber–based composites with polyester. Journal of Applied Polymer Science 131, 40730. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/app.40730/full

Human Foreskin Fibroblasts

Wu, C., & Liao, H. (2014). The mechanical properties, biocompatibility and biodegradability of chestnut shell fibre and polyhydroxyalkanoate composites. Polymer Degradation and Stability 99, 274 – 282. Retrieved from http://www.sciencedirect.com/science/article/pii/S0141391013003558

Mouse Dermal Fibrosis Model

Wu, M., Pedroza, M., Lafyatis, R., George, A. T., & ... (2014). Identification of Cadherin 11 as a Mediator of Dermal Fibrosis and Possible Role in Systemic Sclerosis. Arthritis & Rheumatology 66, 1010 – 1021. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/art.38275/full

Alveolar Epithelial Cells

Xi, Y., Tan, K., Brumwell, A. N., Chen, S. C., & ... (2014). Inhibition of Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis by Methacycline. American Journal of Respiratory Cell and Molecular Biology 50, 51 – 60. Retrieved from http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-0099OC

Mouse Lung

Xu, L., Xiong, S., Guo, R., Yang, Z., Wang, Q., Xiao, F., & ... (2014). Transforming growth factor β3 attenuates the development of radiation-induced pulmonary fibrosis in mice by decreasing fibrocyte recruitment and regulating IFN-γ/IL- 4 Balance. Immunology Letters 162, 27 – 33. Retrieved from http://www.sciencedirect.com/science/article/pii/S0165247814001230

Mouse Lung

Yamaoka, T., Oki, Y., Murata, Y., & Kusumoto, S. (2014). TNF transactivation of EGFR protects EGFR-TKI, gefitinib induced pulmonary epithelial cell apoptosis and injury in TNF transgenic mice. Cancer Research 74, 2277. Retrieved from http://cancerres.aacrjournals.org/content/74/19_Supplement/2277.short

Mouse Dermal Fibroblasts

Yang, L., Murota, H., Serada, S., Fujimoto, M., & ... (2014). Histamine Contributes to Tissue Remodeling via Periostin Expression. Journal of Investigative Dermatology doi: 10.1038/jid.2014.120. Retrieved from http://www.nature.com/jid/journal/vaop/ncurrent/full/jid2014120a.html

Mouse Lung

Yao, X. J., Huang, K. W., Li, Y., Zhang, Q., & ... (2014). Direct comparison of the dynamics of IL‐25‐and “allergen”‐induced airways inflammation, remodelling and hypersensitivity in a murine asthma model. Clinical & Experimental Allergy 44, 765 – 777. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/cea.12298/full

Cheek Tissue and HeLa Cells

Yasmin, H., Kabashima, T., & Rahman, M. (2014). Amplified and selective assay of collagens by enzymatic and fluorescent reactions. Scientific Reports 4, Article No. 4950. Retrieved from http://www.nature.com/srep/2014/140513/srep04950/full/srep04950.html?message-global=remove

Adipose-Derived Stem Cells

Yu, J., Tu, Y. K., Tang, Y. B., & Cheng, N. C. (2014). Stemness and transdifferentiation of adipose-derived stem cells using l-ascorbic acid 2-phosphate-induced cell sheet formation. Biomaterials 35, 3516 – 3526. Retrieved from http://www.sciencedirect.com/science/article/pii/S0142961214000179

Human Periodontal Ligament Stem/Progenitor Cell Line

Yuda, A., Maeda, H., Fujii, S., Monnouchi, S., & ... (2014). Effect of CTGF/CCN2 on osteo/cementoblastic and fibroblastic differentiation of a human periodontal ligament stem/progenitor cell line. Journal of Cellular Physiology 230, 150 – 159. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/jcp.24693/abstract

Mouse Fibroblasts

Zerr, P., Palumbo-Zerr, K., & Huang, J. (2014). Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2014-205740. Retrieved from http://ard.bmj.com/content/early/2014/09/01/annrheumdis-2014-205740.short

Human Fibroblasts and Mouse SSc Skin

Zerr, P., Vollath, S., Palumbo-Zerr, K., Tomcik, M., & ... (2014). Vitamin D receptor regulates TGF-β signalling in systemic sclerosis. Annals of the Rheumatic Diseases doi: 10.1136/annrheudis-2013-204378. Retrieved from http://ard.bmj.com/content/early/2014/01/21/annrheumdis-2013-204378.short

Rat Heart

Zhang, H., Zhong, H., IV, T. E., & Wilson, E. (2014). Blockade of A 2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model. Heart Rhythm 11, 101 – 109. Retrieved from http://www.sciencedirect.com/science/article/pii/S1547527113011600

Rabbit Trochlea

Zhang, W., Lian, Q., Li, D., Wang, K., Hao, D., & ... (2014). Cartilage Repair and Subchondral Bone Migration Using 3D Printing Osteochondral Composites: A One-Year-Period Study in Rabbit Trochlea. BioMed Research International Articl ID 746138, 16 pages. Retrieved from http://www.hindawi.com/journals/bmri/2014/746138/abs/

Adipose-Derived Stem Cells

Zhicheng, Z., Fang, L., Haiquan, T., & Kai, G. (2014). Differentiation of adipose-derived stem cells toward nucleus pulposus-like cells induced by hypoxia and a three-dimensional chitosan-alginate gel scaffold in. Chinese Medical Journal 127, 314 – 321. Retrieved from http://www.cmj.org/ch/reader/create_pdf.aspx?file_no=20130584&flag=1&year_id=2014&quarter_id=2

Mouse Lung Tissue

Zhou, Q., Chen, T., Bozkanat, M., & Ibe, J. (2014). Intratracheal Instillation of High Dose Adenoviral Vectors Is Sufficient to Induce Lung Injury and Fibrosis in Mice. PloS One doi: 10.1371/journal.pone.0116142. Retrieved from http://dx.plos.org/10.1371/journal.pone.0116142.g009

Mouse Lung

Zhou, Y., Peng, H., Sun, H., Peng, X., Tang, C., & ... (2014). Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis. Science Translational Med. 6, 240ra76. Retrieved from http://stm.sciencemag.org/content/scitransmed/6/240/240ra76.full.html

Sircol Assay Citations in Scientific Literature

2013

Murine Kidney Cortex

Abboud,H.E., Ford,B.M., Eid,A.A., Göoz,M., Barnes,J.L. and Gorin,Y.C. (2013) ADAM17 mediates Nox4 expression and NADPH. Am J Physiol Renal Physiol, 305, F323-F332.

Composite Scaffold of Bioglass and Poly (D,L-Lactide)

Abdollahi,S., Ma,A.C.C. and Cerruti,M. (2013) Surface Transformations of Bioglass 45S5 during Scaffold Synthesis for Bone Tissue Engineering. Langmuir, 29, 1466-1474.

Human Periodontal Ligament Cells

Alfonso,A.R., Rath,S., Rafiee,P., Hernandez-Espino,M., Din,M., George,F. and Ramaswamy,S. (2013) Glycosaminoglycan entrapment by fibrin in engineered heart valve tissues. Acta Biomaterialia 9, 8149 – 8157.

Primary Marrow-derived Mesenchymal Stromal Cells

Alford,A.I., Golicz,A.Z., Cathey,A.L. and Reddy,A.B. (2013) Thrombospondin-2 facilitates assembly of a type I collagen-rich matrix in marrow stromal cells undergoing osteoblastic differentiation. Connective tissue research, doi: 10.3109/03008207.2013.811236.

Rat Calvarial Osteoblasts

Allo,B.A., Lin,S., Mequanint,K. and Rizkalla,A.S. (2013) Role of Bioactive 3D Hybrid Fibrous Scaffolds on Mechanical Behavior and Spatiotemporal Osteoblast Gene Expression. ACS applied materials & interfaces, 5, 7574-7583.

Murine Lung

Alnajar,A., Nordhoff,C., Schied,T., Chiquet-Ehrismann,R., Loser,K., Vogl,T., Ludwig,S. and Wixler,V. (2013) The LIM-Only Protein FHL2 Attenuates Lung Inflammation during Bleomycin-Induced Fibrosis. PloS one, 8, e81356.

Rat Liver

Altomonte,J., Marozin,S., De Toni,E.N., Rizzani,A., Esposito,I., Steiger,K., Feuchtinger,A., Hellerbrand,C., Schmid,R.M. and Ebert,O. (2013) Antifibrotic Properties of Transarterial Oncolytic VSV Therapy for Hepatocellular Carcinoma in Rats With Thioacetamide-Induced Liver Fibrosis. Molecular Therapy, 21, 2032-2042.

Murine Lung Tissue

Avasarala,S., Zhang,F., Liu,G., Wang,R., London,S.D. and London,L. (2013) Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Mouse Model of Viral-induced Acute Respiratory Distress Syndrome. PloS one, 8, e57285.

Undetermined Model

Azad,N., Iyer,A.K., Wang,L., Liu,Y., Lu,Y. and Rojanasakul,Y. (2013) Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses. Nanotoxicology, 7, 157-168.

Human Lung Adenocarcinomas and Murine Lung Adenocarcinoma Cell Lines

Baird,B.N., Schliekelman,M.J., Ahn,Y.H., Chen,Y., Roybal,J.D., Gill,B.J., Mishra,D.K., Erez,B., OReilly,M. and Yang,Y. (2013) Fibulin-2 Is a Driver of Malignant Progression in Lung Adenocarcinoma. PloS one, 8, e67054.

Mouse Fibroblast Cell Line L929

Balekar,N., Nakpheng,T., Srichana,T., Jain,D.K., Upadhyay,R.K., Bekele,A., Hymete,A., Bekhit,A.A., Buathet,K. and Chinvarun,Y. (2013) In vitro stimulatory effect of grandiflorenic acid isolated from Wedelia trilobata (L.) leaves on L929 fibroblast cells. Thai Journal of Pharmaceutical Sciences, 37, 117-151.

BJ Human Skin Fibroblast Cells

Balekar,N., Nakpheng,T. and Srichana,T. (2013) Wound-healing potential of grandiflorenic acid isolated from Wedelia trilobata (L.) leaves. Songklanakarin Journal of Science and Technology 35, 537 – 546.

Alveolar Epithelial Cells

Balli,D., Ustiyan,V., Zhang,Y., Wang,I.C., Masino,A.J., Ren,X., Whitsett,J.A., Kalinichenko,V.V. and Kalin,T.V. (2013) Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. The EMBO journal, 32, 231-244.

Murine Lung

Bando,J.K., Nussbaum,J.C., Liang,H.E. and Locksley,R.M. (2013) Type 2 innate lymphoid cells constitutively express arginase-I in the naive and inflamed lung. Journal of leukocyte biology, 94, 877-884.

Microfibrous Scaffold Seeded with Porcine Annulus Fibrosis Cells

Bao,J., Lv,W., Sun,Y. and Deng,Y. (2013) Electrospun antimicrobial microfibrous scaffold for annulus fibrosus tissue engineering. Journal of Materials Science, 48, 4223 - 4232.

Murine Lung

Barreno,R.X., Richards,J.B., Schneider,D.J., Cromar,K.R., Nadas,A.J., Hernandez,C.B., Hallberg,L.M., Price,R.E., Hashmi,S.S. and Blackburn,M.R. (2013) Endogenous osteopontin promotes ozone-induced neutrophil recruitment to the lungs and airway hyperresponsiveness to methacholine. American Journal of Physiology-Lung Cellular and Molecular Physiology 305, L118 – 129.

Murine Lung

Bei,Y., Hua-Huy,T., Duong-Quy,S., Nguyen,V.H., Chen,W., Nicco,C., Batteux,F.d.r. and nh-Xuan,A.T. (2013) Long-term treatment with fasudil improves bleomycin-induced pulmonary fibrosis and pulmonary hypertension via inhibition of Smad2/3 phosphorylation. Pulmonary pharmacology & therapeutics, 26, 635-643.

Murine Lung

Bellaye,P., Wettstein,G., Burgy,O., Besnard,V., Joannes,A., Colas,J., Causse,S., MarchalSomme,J., Fabre,A. and

Crestani,B. (2013) The small heat shock protein αBcrystallin is essential for the nuclear localisation of Smad4: impact on pulmonary fibrosis. The Journal of Pathology, doi: 10.1002/path.4314.

Murine B16/F10 Tumors in Aged 3D Collagen Matrices

Bentov,I., Damodarasamy,M., Plymate,S. and Reed,M.J. (2013) B16/F10 tumors in aged 3D collagen in vitro simulate tumor growth and gene expression in aged mice in vivo. In Vitro Cellular & Developmental Biology-Animal, 49, 395 – 399.

Lung Adencarcinomas (A549) and Lung Squamous Carcinoma (H520)

Bermudez,O., Hennen,E., Koch,I., Lindner,M. and Eickelberg,O. (2013) Gli1 Mediates Lung Cancer Cell Proliferation and Sonic Hedgehog-Dependent Mesenchymal Cell Activation. PloS one, 8, e63226.

Murine Lung

Besnard,A.G.l., Struyf,S., Guabiraba,R., Fauconnier,L., Rouxel,N., Proost,P., Uyttenhove,C., Van Snick,J., Couillin,I. and Ryffel,B. (2013) CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model. Journal of leukocyte biology, 94, 1317-1323.

Crohn’s Disease Myofibroblasts

Biancheri,P., Pender,S.L., Ammoscato,F., Giuffrida,P., Sampietro,G., Ardizzone,S., Ghanbari,A., Curciarello,R., Pasini,A. and Monteleone,G. (2013) The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis. Fibrogenesis & tissue repair, 6, 13.

Dog Mitral Valve

Bigg,P.W., Baldo,G., Sleeper,M.M., O'Donnell,P.A., Bai,H., Rokkam,V.R., Liu,Y., Wu,S., Giugliani,R. and Casal,M.L. (2013) Pathogenesis of mitral valve disease in mucopolysaccharidosis VII dogs. Molecular genetics and metabolism, 110, 319-328.

Murine Left Ventricle

Blömer,N., Pachel,C., Hofmann,U., Nordbeck,P., Bauer,W., Mathes,D., Frey,A., Bayer,B., Vogel,B. and Ertl,G. (2013) 5-Lipoxygenase facilitates healing after myocardial infarction. Basic research in cardiology, 108, 367.

Murine Lung Tissue

Boveda-Ruiz,D., D'Alessandro-Gabazza,C.N., Toda,M., Takagi,T., Naito,M., Matsushima,Y., Matsumoto,T., Kobayashi,T., Gil-Bernabe,P. and Chelakkot-Govindalayathil,A.L. (2013) Differential role of regulatory T cells in early and late stages of pulmonary fibrosis. Immunobiology, 218, 245-254.

Murine Cardiac Tissue

Brunner,S.M., Schiechl,G., Kesselring,R., Martin,M., Balam,S., Schlitt,H.J., Geissler,E.K. and Fichtner-Feigl,S. (2013) IL-13 signaling via IL-13Ralpha2 triggers TGF-β1-dependent allograft fibrosis. Transplantation research, 2, 16.

Equine Tenocytes

Caliari,S.R. and Harley,B.A. (2013) Composite Growth Factor Supplementation Strategies to Enhance Tenocyte Bioactivity in Aligned Collagen-GAG Scaffolds. Tissue Engineering Part A 19, 1100 – 1112.

Murine Lung

Cargnoni,A., Piccinelli,E.C., Ressel,L., Rossi,D., Magatti,M., Toschi,I., Cesari,V., Albertini,M., Mazzola,S. and Parolini,O. (2013) Conditioned medium from amniotic membran-derived cells prevents lung fibrosis and

preserves blood gas exchanges in bleomycin-injured micespecificity of the effects and insights into possible mechanisms. Cytotherapy, http://dx.doi.org/10.1016/j.jcyt.2013.07.002.

Human Adipose Stem Cells

Cerqueira,M.T., Pirraco,R.r.P., Santos,T.C., Rodrigues,D.B., Frias,A.M., Martins,A.R., Reis,R.L. and Marques,A.P. (2013) Human Adipose Stem Cells Cell Sheet Constructs impact epidermal morphogenesis in full-thickness excisional wounds. Biomacromolecules, 14, 3997-4008.

Fibroblasts

Chak,K.F., Hsiao,C.Y. and Chen,T.Y. (2013) A Study of the Effect of Shiunko, a Traditional Chinese Herbal Medicine, on Fibroblasts and Its Implication on Wound Healing Processes. Advances in Wound Care 2, 448 – 455.

Human Dental Pulp Cells

Chang,M.C., Lin,L.D., Tseng,H.C., Chang,B.E., Chan,C.P., Lee,S.Y., Chang,H.H., Lin,P.S., Tseng,S.K. and Jeng,J.H. (2013) Growth and Differentiation Factor-5 Regulates the Growth and Differentiation of Human Dental Pulp Cells. Journal of endodontics, 39, 1272-1277.

Murine Aortic Endothelial Cells

Cheng,S.L., Shao,J.S., Behrmann,A., Krchma,K. and Towler,D.A. (2013) Dkk1 and Msx2Wnt7b Signaling

Reciprocally Regulate the EndothelialMesenchymal Transition in Aortic Endothelial Cells. Arteriosclerosis, thrombosis, and vascular biology, 33, 1679-1689.

Murine Bladder

Chen,J., Drzewiecki,B.A., Merryman,W.D. and Pope IV,J.C. (2013) Murine bladder wall biomechanics following partial bladder obstruction. Journal of Biomechanics, 46, 2752-2755.

Intervertebral disc Tissue

Chen,J., Lee,E.J., Jing,L., Christoforou,N., Leong,K.W. and Setton,L.A. (2013) Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro. PloS one, 8, e75548.

Rabbit Bone Marrow Stromal Cells

Chen,K., Ng,K.S., Ravi,S., Goh,J.C. and Toh,S.L. (2013) In vitro generation of whole osteochondral constructs using

rabbit bone marrow stromal cells, employing a twochambered coculture well design. Journal of tissue engineering and regenerative medicine, doi: 10.1002/term.1716.

Aortic Tissue

Cheng,S.L., Shao,J.S., Behrmann,A., Krchma,K. and Towler,D.A. (2013) Dkk1 and Msx2Wnt7b Signaling

Reciprocally Regulate the EndothelialMesenchymal Transition in Aortic Endothelial Cells. Arteriosclerosis, thrombosis, and vascular biology, 33, 1679-1689.

Murine Dermal Wound

Chereddy,K.K., Coco,R., Memvanga,P.B., Ucakar,B., des Rieux,A., Vandermeulen,G. and Préat,V.+. (2013) Combined effect of PLGA and curcumin on wound healing activity. Journal of Controlled Release, 171, 208-215.

Human Skin Fibroblast Cell Cultures (Hs68)

Chiang,H.M., Chen,H.C., Chiu,H.H., Chen,C.W., Wang,S.M. and Wen,K.C. (2013) Neonauclea reticulata (Havil.) Merr stimulates skin regeneration after UVB exposure via ROS scavenging and modulation of the MAPK/MMPs/collagen pathway. Evidence-Based Complementary and Alternative Medicine Volume 2013, Article ID 324864, 9 pages,2013, http://dx.doi.org/10.1155/2013.324864.

Rat Liver

Choi,J.H., Jin,S.W., Kim,H.G., Khanal,T., Hwang,Y.P., Lee,K.J., Choi,C.Y., Chung,Y.C., Lee,Y.C. and Jeong,H.G. (2013) Platycodi Radix attenuates dimethylnitrosamine-induced liver fibrosis in rats by inducing Nrf2-mediated antioxidant enzymes. Food and Chemical Toxicology 56, 231 – 239.

Human Dermal Fibroblasts

Cho,S.Y., Seo,D.B., Kim,W.G. and Lee,S.J. (2013) Mild Mitochondrial Uncoupling Prevents Premature Senescence in Human Dermal Fibroblasts. Journal of Investigative Dermatology, doi: 10.1038/jid.2013.352.

Rat Lung

Cho,Y.J., Yi,C.O., Jeon,B.T., Jeong,Y.Y., Kang,G.M., Lee,J.E., Roh,G.S. and Lee,J.D. (2013) Curcumin Attenuates Radiation-Induced Inflammation and Fibrosis in Rat Lungs. The Korean Journal of Physiology & Pharmacology, 17, 267-274.

Human Umbilical Cord Mesenchymal Stromal cells

Chon,B.H., Lee,E.J., Jing,L., Setton,L.A. and Chen,J. (2013) Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-3D culture system. Stem Cell Res Ther, 4, 120.

Porcine Thoracic Aorta

Chow,M.J., Mondonedo,J.R., Johnson,V.M. and Zhang,Y. (2013) Progressive structural and biomechanical changes in elastin degraded aorta. Biomechanics and Modeling in Mechanobiology, 12, 361 - 372.

Mouse Renal Tissue

Chung,H., Hollenberg,M.D. and Muruve,D.A. (2013) Proteinase-activated receptor-2 transactivation of EGF-and TGFβ-receptor signaling pathways contributes to renal fibrosis. Journal of Biological Chemistry, doi: 10.1074/jbc.M113.492793.

Murine Lung

Citrin,D.E., Shankavaram,U., Horton,J.A., Shield,W., Zhao,S., Asano,H., White,A., Sowers,A., Thetford,A. and Chung,E.J. (2013) Role of type II pneumocyte senescence in radiation-induced lung fibrosis. Journal of the National Cancer Institute, 105, 1474-1484.

Human Lung Tissue and Fibroblast Cell Lines

Conte,E., Gili,E., Fruciano,M., Korfei,M., Fagone,E., Iemmolo,M., Furno,D.L., Giuffrida,R., Crimi,N. and Guenther,A. (2013) PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition. Laboratory Investigation, 93, 566-576.

Murine Lung

Conte,E., Genovese,T., Gili,E., Esposito,E., Iemmolo,M., Fruciano,M., Fagone,E., Pistorio,M.P., Crimi,N. and

Cuzzocrea,S. (2013) Thymosin +¦4 protects C57BL/6 mice from bleomycininduced damage in the lung. European journal of clinical investigation 43, 309 – 315.

Pulmonary Tissue

Cox,T.R., Bird,D., Baker,A.M., Barker,H.E., Ho,M.W., Lang,G. and Erler,J.T. (2013) LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis. Cancer research, 73, 1721-1732.

Autogenic Osteoblast- or Chondrocyte Induced Bone Marrow Stromal Cells

Da,H., Jia,S.J., Meng,G.L., Cheng,J.H., Zhou,W., Xiong,Z., Mu,Y.J. and Liu,J. (2013) The Impact of Compact Layer in Biphasic Scaffold on Osteochondral Tissue Engineering. PloS one, 8, e54838.

Male Calf Wound

Das,J., Nath,L., Routray,P., Das,R.K., Behera,S.S. and Purohit,G.K. Targeting chronic Ulcerative wound at thigh region in a bull calf by autologous stem cell therapy. E-planet 10, 12 – 16.

Bone Marrow-Derived Mesenchymal Stem Cells

Das,J., Nath,I., Routray,P., Behera,S.S. and Purohit,G.K. (2013) Stem cell therapy for chronic ulcerative wound in a dog. Indian Journal of Veterinary Surgery, 34, 67.

Bone Marrow-Derived Mesenchymal Stem Cells

Das,J., Nath,I., Routray,P. and Das,R.K. (2013) Autologous Bone Marrow derived Mesenchymal Stem Cells (BM-MSCs) therapy for treatment of Chronic Limb Wound in a Bull. Intas Polivet, 14, 61-66.

Murine Lung

Das,S., Kumar,M., Negi,V., Pattnaik,B., Prakash,Y.S., Agrawal,A. and Ghosh,B. (2013) MicroRNA-326 Regulates Pro-Fibrotic Functions of Transforming Growth Factor-β in Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology, doi: 10.1165/rcmb.2013-01950c.

Murine Lung

Dhanda,D.S., Tyagi,P., Mirvish,S.S. and Kompella,U.B. (2013) Supercritical Fluid Technology Based Large Porous Celecoxib-PLGA Microparticles Do Not Induce Pulmonary Fibrosis and Sustain Drug Delivery and Efficacy for Several Weeks Following A Single Dose. Journal of Controlled Release 168, 239 – 250.

Human Colonic Epithelial Cells and Subepithelial Myofibroblasts

Drygiannakis,I., Valatas,V., Sfakianaki,O., Bourikas,L., Manousou,P., Kambas,K., Ritis,K., Kolios,G. and Kouroumalis,E. (2013) Proinflammatory cytokines induce crosstalk between colonic epithelial cells and subepithelial myofibroblasts: Implication in intestinal fibrosis. Journal of Crohn's and Colitis, 7, 286-300.

Human Wharton’s-Jelly Derived Mesenchymal Stromal Cells (WJ-MSCs)

Du,T., Zou,X., Cheng,J., Wu,S., Zhong,L., Ju,G., Zhu,J., Liu,G., Zhu,Y. and Xia,S. (2013) Human Wharton's jelly-derived mesenchymal stromal cells reduce renal fibrosis through induction of native and foreign hepatocyte growth factor synthesis in injured tubular epithelial cells. Stem cell research & therapy, 4, 59.

Rat Lung

Ermis,H., Parlakpinar,H., Gulbas,G., Vardi,N., Polat,A., Cetin,A., Kilic,T. and Aytemur,Z.A. (2013) Protective effect of dexpanthenol on bleomycin-induced pulmonary fibrosis in rats. Naunyn-Schmiedeberg's archives of pharmacology, 386, 1103-1110.

Basement Membrane Complex of Porcine Urinary Bladder

Faulk,D.M., Carruthers,C.A., Warner,H.J., Kramer,C.R., Reing,J.E., Zhang,L., D’Amore,A. and Badylak,S.F. (2014) The effect of detergents on the basement membrane complex of a biologic scaffold material. Acta biomaterialia, 10, 183-193.

Porcine Papillary Dermis and Epidermis

Fernandes,J.R., Samayoa,J.C., Broelsch,G.F., McCormack,M.C., Nicholls,A.M., Randolph,M.A., Mihm,M.C. and usten Jr,W.G. (2013) Micro-Mechanical Fractional Skin Rejuvenation. Plastic and reconstructive surgery, 131, 216-223.

Murine Lung

Ferreira,T.P., de Arantes,A.C., do Nascimento,C.V.M., Olsen,P.C., Trentin,P.c.G., Rocco,P.R., Hogaboam,C.M., Puri,R.K., Martins,M.A.l. and Silva,P.c.M.R. (2013) IL-13 Immunotoxin Accelerates Resolution of Lung Pathological Changes Triggered by Silica Particles in Mice. The Journal of Immunology, 191, 5220-5229.

Human Umbilical Cord Warton’s Jelly stem Cells

Fong,C., Tam,K., Cheyyatraivendran,S., Gan,S., Gauthaman,K., Armugam,A., Jeyaseelan,K., Choolani,M., Biswas,A. and Bongso,A. (2013) Human umbilical cord Wharton's jelly stem cells and its conditioned medium enhance healing of excisional and diabetic wounds. Journal of cellular biochemistry, doi: 10.1002/jcb.24661.

Murine Kidney Cortex

Ford,B.M., Eid,A.A., Gooz,M., Barnes,J.L., Gorin,Y.C. and Abboud,H.E. (2013) ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice. American Journal of Physiology-Renal Physiology 305, F323 – 32.

Co-Culture of Human Blood B Cells and Dermal Fibroblasts

François,A., Chatelus,E., Wachsmann,D., Sibilia,J., Bahram,S., Alsaleh,G. and Gottenberg,J.E. (2013) B lymphocytes and B cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis. Arthritis research & therapy, 15, R168.

Human Lung Fibroblasts

Gabasa,M., Royo,D., Molina-Molina,M., Roca-Ferrer,J., Pujols,L., Picado,C., Xaubet,A. and Pereda,J. (2013) Lung Myofibroblasts Are Characterized by Down-Regulated Cyclooxygenase-2 and Its Main Metabolite, Prostaglandin E2. PloS one, 8, e65445.

Rat Lung

Gao,F., Fish,B.L., Moulder,J.E., Jacobs,E.R. and Medhora,M. (2013) Enalapril Mitigates Radiation-Induced Pneumonitis and Pulmonary Fibrosis if Started 35 Days after Whole-Thorax Irradiation. Radiation research 180, 546 – 552.

Rat Lung

Gao,F., Narayanan,J., Joneikis,C., Fish,B.L., Szabo,A., Moulder,J.E., Molthen,R.C., Jacobs,E.R., Rao,R.N. and Medhora,M. (2013) Enalapril Mitigates Focal Alveolar Lesions, A Histological Marker of Late Pulmonary Injury by Radiation to the Lung. Radiation research, 179, 465-474.

Murine Lung

Garcia,O., Carraro,G., Turcatel,G., Hall,M., Sedrakyan,S., Roche,T., Buckley,S., Driscoll,B., Perin,L. and Warburton,D. (2013) Amniotic Fluid Stem Cells Inhibit the Progression of Bleomycin-Induced Pulmonary Fibrosis via CCL2 Modulation in Bronchoalveolar Lavage. PloS one, 8, e71679.

Murine Lung

Garibaldi,B.T., D'Alessio,F.R., Mock,J.R., Files,D.C., Chau,E., Eto,Y., Drummond,M.B., Aggarwal,N.R., Sidhaye,V. and King,L.S. (2013) Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment. American Journal of Respiratory Cell and Molecular Biology, 48, 35-43.

Osteoblasts and Osteoclasts

Ghag,A.K., Gough,J.E. and Downes,S. (2014) The osteoblast and osteoclast responses to phosphonic acid containing poly (+Á-caprolactone) electrospun scaffolds. Biomaterials Science doi: 10.1039/C3BM60188A.

Murine Lung

Gharib,S.A., Johnston,L.K., Huizar,I., Birkland,T.P., Hanson,J., Wang,Y., Parks,W.C. and Manicone,A.M. (2013) MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis. Journal of leukocyte biology, doi: 10.1189/ jlb-1112587.

Human and Porcine Lung

Gilpin,S.E., Guyette,J.P., Gonzalez,G., Ren,X., Asara,J.M., Mathisen,D.J., Vacanti,J.P. and Ott,H.C. (2013) Perfusion Decellularization of Human and Porcine Lungs: Bringing the Matrix to Clinical Scale. The Journal of Heart and Lung Transplantation, http://dx.doi.org/10.1016/j.healun.2013.10.030.

Murine Embryonic Stem Cells (CRL-1934)

Goh,S.K., Olsen,P. and Banerjee,I. (2013) Extracellular Matrix Aggregates from Differentiating Embryoid Bodies as a Scaffold to Support ESC Proliferation and Differentiation. PloS one, 8, e61856.

Rat Dermal Wound

Gong,C., Wu,Q., Wang,Y., Zhang,D., Luo,F., Zhao,X., Wei,Y. and Qian,Z. (2013) A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing. Biomaterials 34, 6377 – 6387.

Murine Lung

Gregory,L.G., Jones,C.P., Mathie,S.A., Pegorier,S. and Lloyd,C.M. (2013) Endothelin1 directs airway remodeling

and hyperreactivity in a murine asthma model. Allergy 68, 1579 – 1588.

Murine Lung Tissue

Gregory,L.G., Jones,C.P., Walker,S.A., Sawant,D., Gowers,K.H., Campbell,G.A., McKenzie,A.N. and Lloyd,C.M. (2013) IL-25 drives remodelling in allergic airways disease induced by house dust mite. Thorax, 68, 82-90.

Murine Colon

Guan,Q., Burtnick,H.A., Qing,G., Weiss,C.R., Ma,A.G., Ma,Y., Warrington,R.J. and Peng,Z. (2013) Employing an IL-23 p19 vaccine to block IL-23 ameliorates chronic murine colitis. Immunotherapy, 5, 1313-1322.

Rat Skeletal Muscle

Gupta,A.R., Dey,S., Swarup,D., Sainid,M. and Izatnagar,I. (2013) Effects of excessive fluoride ingestion on collagen protein and expression of type 1 collagen gene in skeletal muscles of rats. Fluoride 46, 149 – 155.

Rat Lung

Gustafsson,A., SvenssonElfsmark,L., Lorentzen,J.C. and Bucht,A. (2013) Strain differences influence timing and magnitude of both acute and late inflammatory reactions after intratracheal instillation of an alkylating agent in rats. Journal of Applied Toxicology doi: 10.1002/jat2878.

Engineered Fibrocartilage

Hadidi,P. and Athanasiou,K.A. (2013) Enhancing the mechanical properties of engineered tissue through matrix remodeling via the signaling phospholipid lysophosphatidic acid. Biochemical and Biophysical Research Communications 433, 133 – 138.

Rat Myocardial Tissue

Hamdani,N., Franssen,C., Lourenço,A., Falão-Pires,I., Fontoura,D., Leite,S., Plettig,L., López,B.a., Ottenheijm,C.A. and Becher,P.M. (2013) Myocardial Titin Hypophosphorylation Importantly Contributes to Heart Failure With Preserved Ejection Fraction in a Rat Metabolic Risk Model. Circulation: Heart Failure, 6, 1239-1249.

Porcine Aortic Valve Leaflets

Hammer,P.E., Pacak,C.A., Howe,R.D. and del Nido,P.J. (2013) Straightening of curved pattern of collagen fibers under load controls aortic valve shape. Journal of Biomechanics http://dx.doi.org/10.1016/j.jbiomech.2013.11.032.

Porcine Aortic Valves

Hammer,P.E., Pacak,C.A., Howe,R.D. and Pedro,J. (2013) Collagen Bundle Orientation Explains Aortic Valve Leaflet Coaptation. In Functional Imaging and Modeling of the Heart, pp. 409-415. Springer.

Murine Lung

Hartopo,A.B., Emoto,N., Vignon-Zellweger,N., Suzuki,Y., Yagi,K., Nakayama,K. and Hirata,K.i. (2013) Endothelin-

Converting Enzyme1 Gene Ablation Attenuates Pulmonary Fibrosis via CGRP-cAMP/EPAC1 Pathway. American Journal of Respiratory Cell and Molecular Biology, 48, 465-476.

Primary Human Osteoblast Cell Line

Hasan,M.S., Ahmed,I., Parsons,A.J., Walker,G.S. and Scotchford,C.A. (2013) The influence of coupling agents on mechanical property retention and long-term cytocompatibility of phosphate glass fibre reinforced PLA composites. Journal of the mechanical behavior of biomedical materials, 28, 1-14.

Human Osteosarcoma (MG63) and Primary Human Osteoblast Cell Lines

Hasan,S., Ahmed,I., Parsons,A.J., Walker,G.S. and Scotchford,C.A. (2013) Cytocompatibility assessment of chemical surface treatments for phosphate glass to improve adhesion between glass and polyester. Journal of Biomedical Materials Research Part A, 101, 3301-3310.

Murine Lung

Hasan,S.A., Eksteen,B., Reid,D., Paine,H.V., Alansary,A., Johannson,K., Gwozd,C., Goring,K.A., Vo,T. and Proud,D. (2013) Role of IL-17A and neutrophils in fibrosis in experimental hypersensitivity pneumonitis. Journal of Allergy and Clinical Immunology 131, 1663 – 1673.e5.

Microporous Elastic Patch on Rat left Ventricular Lesions

Hashizume,R., Hong,Y., Takanari,K., Fujimoto,K.L., Tobita,K. and Wagner,W.R. (2013) The effect of polymer degradation time on functional outcomes of temporary elastic patch support in ischemic cardiomyopathy. Biomaterials 34, 7353 – 7363.

Murine Lung

Henderson Jr,W.R., Ye,X., Lai,Y., Ni,Z., Bollinger,J.G., Tien,Y.T., Chi,E.Y. and Gelb,M.H. (2013) Key Role of Group V Secreted Phospholipase A2 in Th2 Cytokine and Dendritic Cell-Driven Airway Hyperresponsiveness and Remodeling. PloS one, 8, e56172.

Human Bone Marrow-Derived Mesenchymal Stem Cells

Hegner,B., Schaub,T., Catar,R., Kusch,A., Wagner,P., Essin,K., Lange,C., Riemekasten,G., Dragun,D. and Berlin,C.U. Deregulated vascular smooth muscle cell differentiation with increased propensity towards myofibroblastic phenoconversion of mesenchymal stem cells from patients with systemic sclerosis. essinek.com/pdfs/Hegner_B_submitted_2013.pdf

Murine Lung Tissue

Hirata,H., Arima,M., Fukushima,Y., Sugiyama,K., Tokuhisa,T. and Fukuda,T. (2013) Leukotriene C4 aggravates

bleomycininduced pulmonary fibrosis in mice. Respirology, 18, 674-681.

Murine Bone Marrow-Derived Mast Cells

Hong,G.U., Park,B.S., Park,J.W., Kim,S.Y. and Ro,J.Y. (2013) IgE production in CD40/CD40L cross-talk of B and mast cells and mediator release via TGase 2 in mouse allergic asthma. Cellular Signalling 25, 1514 – 1525.

Murine Skin after Infusion with Bone Marrow-Derived Mesenchymal Stem Cells

Horton,J.A., Hudak,K.E., Chung,E.J., White,A.O., Scroggins,B.T., Burkeen,J.F. and Citrin,D.E. (2013) Mesenchymal

stem cells inhibit cutaneous radiationinduced fibrosis by suppressing chronic inflammation. Stem Cells, 31, 2231-2241.

Murine Hind Limb

Horton,J., Li,F., Chung,E.J., Hudak,K., White,A., Krausz,K., Gonzalez,F. and Citrin,D. (2013) Quercetin Inhibits Radiation-Induced Skin Fibrosis. Radiation Research, http://dx.doi.org/10.1667/RR3237.1.

Rabbit Medial Collateral Ligament

Hsu,W., Peng,K., Lai,L., Hung,C. and Chang,P. (2013) Cellular senescence occurring in the rabbit medial collateral ligament during healing. Journal of Orthopaedic Research, 31, 81-90.

Murine Lung

Huang,J., Li,Z., Yao,X., Li,Y., Reng,X., Li,J., Wang,W., Gao,J., Wang,C. and Tankersley,C.G. (2013) Altered Th1/Th2 commitment contributes to lung senescence in CXCR3-deficient mice. Experimental Gerontology 48, 717 – 726.

Human Murine Lung

Huang,L.S., Berdyshev,E., Mathew,B., Fu,P., Gorshkova,I.A., He,D., Ma,W., Noth,I., Ma,S.F. and Pendyala,S. (2013) Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis. The FASEB Journal, 27, 1749-1760.

Murine Lung

Huang,L.S., Fu,P., Patel,P., Harijith,A., Sun,T., Zhao,Y., Garcia,J.G., Chun,J. and Natarajan,V. (2013) Lysophosphatidic Acid Receptor 2 Deficiency Confers Protection Against Bleomycin-Induced Lung Injury and Fibrosis in Mice. American journal of respiratory cell and molecular biology 49, 912 – 922.

Rabbit Osteoarthritis Model

Huh,J.E., Park,Y.C., Seo,B.K., Lee,J.D., Baek,Y.H., Choi,D.Y. and Park,D.S. (2013) Cartilage Protective and Chondrogenic Capacity of WIN-34B, a New Herbal Agent, in the Collagenase-Induced Osteoarthritis Rabbit Model and in Progenitor Cells from Subchondral Bone. Evidence-Based Complementary and Alternative Medicine, http://dx.doi.org/10.1155/2013/527561.

Murine Skin

Huu,D.L., Matsushita,T., Jin,G., Hamaguchi,Y., Hasegawa,M., Takehara,K. and Fujimoto,M. (2013) FTY720

Ameliorates Murine Sclerodermatous Chronic GraftÇÉVersusÇÉHost Disease by Promoting Expansion of Splenic Regulatory Cells and Inhibiting Immune Cell Infiltration Into Skin. Arthritis & Rheumatism, 65, 1624-1635.

Murine Aortic Root Lesions

Ishibashi,M., Sayers,S., Armiento,D., Tall,A.R. and Welch,C.L. (2013) TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaques. Atherosclerosis 229, 52 – 61.

Polyvinyl Alcohol Sponge from Tail Wound of a Mouse

Iwamoto,S., Lin,X., Ramirez,R., Carson,P., Fiore,D., Goodrich,J., Yufit,T. and Falanga,V. (2013) Bone Marrow Cell Mobilization by the Systemic Use of Granulocyte Colony-Stimulating Factor (GCSF) Improves Wound Bed Preparation. The International Journal of Lower Extremity Wounds, doi: 10.1177/1534734613513401.

Rat Abdominal Aorta, Mesenteric and Femoral Arteries.

Jelinic,M., Leo,C.H., Uiterweer,E.D.P., Sandow,S.L., Gooi,J.H., Wlodek,M.E., Conrad,K.P., Parkington,H., Tare,M. and Parry,L.J. (2013) Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment. The FASEB Journal, doi: 10.1096/fj.13-233429.

Monkey Selected Chondrogenic Clonal Mesenchymal Stem Cells

Jiang,L., Ma,A., Song,L., Hu,Y., Dun,H., Daloze,P., Yu,Y., Jiang,J., Zafarullah,M. and Chen,H. (2013) Cartilage

regeneration by selected chondrogenic clonal mesenchymal stem cells in the collagenaseinduced monkey osteoarthritis model. Journal of tissue engineering and regenerative medicine, doi: 10.1002/term.1676.

Murine Lung

Jonasson,S., Wigenstam,E., Koch,B. and Bucht,A. (2013) Early treatment of chlorine-induced airway hyperresponsiveness and inflammation with corticosteroids. Toxicology and applied pharmacology 271, 168 – 174.

Sheep Liver Tissue

Kajbafzadeh,A.M., Javan-Farazmand,N., Monajemzadeh,M. and Baghayee,A. (2013) Determining the Optimal Decellularization and Sterilization Protocol for Preparing a Tissue Scaffold of a Human-Sized Liver Tissue. Tissue Engineering Part C: Methods 19, 642 – 651.

Rat Hepatic Stellate Cells

Kaji,K., Yoshiji,H., Ikenaka,Y., Noguchi,R., Aihara,Y., Douhara,A., Moriya,K., Kawaratani,H., Shirai,Y. and Yoshii,J. (2013) Dipeptidyl peptidase-4 inhibitor attenuates hepatic fibrosis via suppression of activated hepatic stellate cell in rats. Journal of Gastroenterology, doi: 10.1007/s00535-013-0783-4.

Nasal Polyp Derived Fibroblasts

Kang,J.S., Park,I., Cho,J., Hong,S., Kim,T.H., Lee,S.H. and Lee,H. (2013) Epigallocatechin3Gallate Inhibits

Collagen Production of Nasal PolypDerived Fibroblasts. Phytotherapy Research, doi: 10.1002/ptr.4971.

Myofibroblast Cells

Kang,Y., Choi,Y., Yun,C., Park,J., Suk,K., Kim,H., Park,M., Lee,B., Lee,H. and Moon,S. (2013) Downregulation of collagen synthesis and matrix metalloproteinase expression in myofibroblasts from dupuytren nodule using

adenovirusmediated relaxin gene therapy. Journal of Orthopaedic Research, doi: 10.1002/jor.22535.

Murine Skin Tissue

Kanno,Y., Kawashita,E., Kokado,A., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2013) Alpha2antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F2+¦ synthesis through adipose

triglyceride lipase/calciumindependent phospholipase A2. Arthritis & Rheumatism, 65, 492-502.

Murine Lung

Kao,S.T. (2013) The Chinese Herbal Medicine Formula Sheng-Fei-Yu-Chuan-Tang Suppresses Th2 Responses and Increases IFNγ in Dermatophagoides pteronyssinus Induced Chronic Asthmatic Mice. Evidence-Based Complementary and Alternative Medicine, http://dx.doi.org/10.1155/2013/984121.

Neonatal Rat Cardiac Fibroblast Cells and Cardiomyocytes

Kharaziha,M., Nikkhah,M., Shin,S.R., Annabi,N., Masoumi,N., Gaharwar,A.K., Camci-Unal,G. and Khademhosseini,A. (2013) PGS: Gelatin nanofibrous scaffolds with tunable mechanical and structural properties for engineering cardiac tissues. Biomaterials 34, 6355 – 6366.

Murine Liver, Human Hepatic Stellate Cells LX-2 and Rat Primary Hepatic Stellate Cells

Kim,J.H., Jeong,Y.J., Hong,J.M., Kim,H.R., Kang,J.S., Lee,W.J. and Hwang,Y.i. (2014) Chronic vitamin C insufficiency aggravated thioacetamide-induced liver fibrosis in gulo-knockout mice. Free Radical Biology and Medicine, 67, 81-90.

Fibroblasts and Murine Models of Dermal Fibrosis

Krämer,M., Dees,C., Huang,J., Schlottmann,I., Palumbo-Zerr,K., Zerr,P., Gelse,K., Beyer,C., Distler,A. and Marquez,V.E. (2013) Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis. Annals of the Rheumatic Diseases, 72, 614-620.

Rat HSC and Lx-2 Cells and Rat Liver Tissue

Kubo,N., Saito,R., Hamano,K., Nagasawa,M., Aoki,F., Takei,I., Umezawa,K., Kuwano,H. and Kojima,I. (2013)

Conophylline suppresses hepatic stellate cells and attenuates thioacetamideinduced liver fibrosis in rats. Liver International doi: 10.1111/liv.12328.

Umbilical Cord Blood Derived Mesenchymal Stem Cells

Kumar Mekala,N., Raju Baadhe,R., Rao Parcha,S. and Devi,Y. (2013) Enhanced Proliferation and Osteogenic Differentiation of Human Umbilical Cord Blood Stem Cells by L-Ascorbic Acid, In Vitro. Current Stem Cell Research & Therapy, 8, 156-162.

Bovine Intervertebral Disc Cells

Kwon,Y.J., Lee,J.W., Moon,E.J., Chung,Y.G., Kim,O.S. and Kim,H.J. (2013) Anabolic Effects of Peniel 2000, a Peptide That Regulates TGF-β1 Signaling on Intervertebral Disc Degeneration. Spine, 38, E49-E58.

Human Adipose Stem Cells

Kyllönen,L., Haimi,S., Säkkinen,J., Kuokkanen,H., Mannerström,B., Sándor,G.K. and Miettinen,S. (2013) Exogenously added BMP-6, BMP-7 and VEGF may not enhance the osteogenic differentiation of human adipose stem cells. Growth Factors, 31, 141-153.

Porcine Myocardium

Ladage,D., Yaniz-Galende,E., Rapti,K., Ishikawa,K., Tilemann,L., Shapiro,S., Takewa,Y., Muller-Ehmsen,J., Schwarz,M. and Garcia,M.J. (2013) Stimulating Myocardial Regeneration with Periostin Peptide in Large Mammals Improves Function Post-Myocardial Infarction but Increases Myocardial Fibrosis. PloS one, 8, e59656.

Murine Skin

Le Huu,D., Matsushita,T., Jin,G., Hamaguchi,Y., Hasegawa,M., Takehara,K. and Fujimoto,M. (2013) FTY720

ameliorates murine SclcGVHD by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin. Arthritis & Rheumatism, doi: 10.1002/art.37933.

Murine Lung

Lee,E.h., Lee,E.j., Kim,H.j., Jang,A.s., Koh,E.s., Uh,S.t., Kim,Y.h., Park,S.w. and Park,C.s. (2013) Overexpression of Apolipoprotein A1 in the Lung Abrogates Fibrosis in Experimental Silicosis. PloS one, 8, e55827.

Nasal Mucosae

Lee,H.M. (2013) Tissue Remodeling in Rhinosinusitis. Korean Journal of Otorhinolaryngology-Head and Neck Surgery, 56, 327-331.

Nasal Polyp-Derived Fibroblasts

Lee,H.M. and Hong,S.M. (2013) Epigenetic Regulation of Myofibroblast Differentiation and Extracellular Matrix Production in Nasal Polyp-Derived Fibroblasts. Journal of Allergy and Clinical Immunology, 131, AB329.

Rabbit Articular Chondrocytes

Lee,S.Y., Wee,A.S., Lim,C.K., Abbas,A.A., Selvaratnam,L., Merican,A.M., Ahmad,T.S. and Kamarul,T. (2013) Supermacroporous poly (vinyl alcohol)-carboxylmethyl chitosan-poly (ethylene glycol) scaffold: an in vitro and in vivo pre-assessments for cartilage tissue engineering. Journal of Materials Science: Materials in Medicine, 24, 1561 – 1570.

Murine Inferior Vena Cava

Lee,Y.U., Naito,Y., Kurobe,H., Breuer,C.K. and Humphrey,J.D. (2013) Biaxial mechanical properties of the inferior vena cava in C57BL/6 and CB-17 SCID/bg mice. Journal of Biomechanics, 46, 2277-2282.

Biomacromolecule Blend of Atelocollagen, Hyaluronan and Native Gellan.

Lefter,C.M., Maier,S.S., Maier,V., Popa,M. and Desbrieres,J. (2013) Engineering preliminaries to obtain reproducible mixtures of atelocollagen and polysaccharides. Materials Science and Engineering: C 33, 2323 – 2331.

Murine Lung

Le Saux,C.J., Davy,P., Brampton,C., Ahuja,S.S., Fauce,S., Shivshankar,P., Nguyen,H., Ramaseshan,M., Tressler,R. and Pirot,Z. (2013) A Novel Telomerase Activator Suppresses Lung Damage in a Murine Model of Idiopathic Pulmonary Fibrosis. PloS one, 8, e58423.

Murine Colon, Terminal Ileum, Lung and Liver tissue

Leung,G., Wang,A., Fernando,M., Phan,V.C. and McKay,D.M. (2013) Bone marrow-derived alternatively activated macrophages reduce colitis without promoting fibrosis: participation of IL-10. American Journal of Physiology-Gastrointestinal and Liver Physiology, 304, G781-G792.

MG63 Cells Human Osteosarcoma Cell Line

Li,J., Wei,L., Sun,J. and Guan,G. (2013) Effect of ionic products of dicalcium silicate coating on osteoblast differentiation and collagen production via TGF-β1 pathway. Journal of Biomaterials Applications, 27, 595-604.

Renal Tissue and Fibroblasts

Li,L., Shen,Y., Ding,Y., Liu,Y., Su,D. and Liang,X. (2013) Hrd1 participates in the regulation of collagen I synthesis in renal fibrosis. Molecular and cellular biochemistry, doi: 10.1007/s11010-013-1843-2.

Human Embryonic Stem Cells

Li,M., Li,X., Meikle,M.C., Islam,I. and Cao,T. (2013) Short periods of cyclic mechanical strain enhance triple-supplement directed osteogenesis and bone nodule formation by human embryonic stem cells in vitro. Tissue Engineering Part A 19, 2130 – 2137.

L929 Fibroblast Cells, Murine Fibrosarcoma Cell Line

Lin,H.Y., Peng,C.W. and Wu,W.W. (2013) Fibrous hydrogel scaffolds with cells embedded in the fibers as a potential tissue scaffold for skin repair. Journal of Materials Science: Materials in Medicine, doi: 10.1007/s10856-013-5065-4.

Pulmonary Tissue

Li,R., Wang,X., Ji,Z., Sun,B., Zhang,H., Chang,C.H., Lin,S., Meng,H., Liao,Y.P. and Wang,M. (2013) The Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity. ACS Nano 7, 2352 – 2368.

Osteoblasts

Lin,H.Y. and Chen,J.H. (2013) Osteoblast Differentiation and Phenotype Expressions on Chitosan-coated Ti-6Al-4V. Carbohydrate Polymers 97, 618 – 626.

Murine Fibroblast Cells (L929)

Lin,H.Y., Chen,H.H., Chang,S.H. and Ni,T.S. (2013) Pectin-chitosan-PVA nanofibrous scaffold made by electrospinning and its potential use as a skin tissue scaffold. Journal of Biomaterials Science, Polymer Edition, 24, 470-484.

Murine Decellularised Adipose Tissue

Lu,Q., Li,M., Zou,Y. and Cao,T. (2013) Delivery of basic fibroblast growth factors from heparinized decellularized adipose tissue stimulates potent de novo adipogenesis. Journal of Controlled Release, doi: 10.1016/j.jconrel.2013.11.007.

Murine Lung

Luzina,I.G., Kopach,P., Lockatell,V., Kang,P.H., Nagarsekar,A., Burke,A.P., Hasday,J.D., Todd,N.W. and Atamas,S.P. (2013) Interleukin-33 Potentiates Bleomycin-induced Lung Injury. American Journal of Respiratory Cell and Molecular Biology 49, 999 – 1008.

Mesenchymal Stem Cell-Loaded Monkey Acellular Dermal Matrix

Ma,A., Jiang,L., Song,L., Hu,Y., Dun,H., Daloze,P., Yu,Y., Jiang,J., Zafarullah,M. and Chen,H. (2013) Reconstruction of cartilage with clonal mesenchymal stem cell-acellular dermal matrix in cartilage defect model in nonhuman primates. International immunopharmacology 16, 399 – 408.

Murine Lung

Ma,Y., Halayko,A.J., Basu,S., Guan,Q., Weiss,C.R., Ma,A.G., HayGlass,K.T., Becker,A.B., Warrington,R.J. and Peng,Z. (2013) Sustained Suppression of IL-13 by a Vaccine Attenuates Airway Inflammation and Remodeling in Mice. American Journal of Respiratory Cell and Molecular Biology, 48, 540-549.

Co-Cultures of Meniscus Cells and Articular Chondrocytes

MacBarb,R.F., Chen,A.L., Hu,J.C. and Athanasiou,K.A. (2013) Engineering functional anisotropy in fibrocartilage neotissues. Biomaterials 34, 9980-9989.

Murine Lung

Makino,H., Aono,Y., Azuma,M., Kishi,M., Yokota,Y., Kinoshita,K., Takezaki,A., Kishi,J., Kawano,H. and Ogawa,H. (2013) Antifibrotic effects of CXCR4 antagonist in bleomycin-induced pulmonary fibrosis in mice. The Journal of Medical Investigation, 60, 127 – 137.

Engineered Neo Cartilage

Makris,E.A., MacBarb,R.F., Responte,D.J., Hu,J.C. and Athanasiou,K.A. (2013) A copper sulfate and hydroxylysine treatment regimen for enhancing collagen cross-linking and biomechanical properties in engineered neocartilage. The FASEB Journal, 27, 2421-2430.

Human Vascular Smooth Muscle Cells, Endothelial Cells and Bone Marrow-Derived Mesenchymal Stem Cells

Martinez,C., Henao,A., Rodriguez,J.E., Padgett,K.R. and Ramaswamy,S. (2013) Monitoring steady flow effects on cell distribution in engineered valve tissues by magnetic resonance imaging. Molecular Imaging, 12, 1 - 13.

Human Periodontal Ligament Cells

Martinez,C., Rath,S., Van Gulden,S., Pelaez,D., Alfonso,A., Fernandez,N., Kos,L., Cheung,H. and Ramaswamy,S. (2013) Periodontal Ligament Cells Cultured under Steady Flow Environments Demonstrate Potential for Use in Heart Valve Tissue Engineering. Tissue Engineering 19, 458 – 466.

Murine Skin and Lung

Marut,W., Jamier,V., Kavian,N., Servettaz,A.l., Winyard,P.G., Eggleton,P., Anwar,A., Nicco,C., Jacob,C. and Chéreau,C. (2013) The natural organosulfur compound dipropyltetrasulfide prevents HOCl-induced Systemic sclerosis in the mouse. Arthritis research & therapy, 15, R167.

Murine Skin and Lung Tissue

Marut,W., Kavian,N., Servettaz,A.l., HuaHuy,T., Nicco,C., Chóreau,C., Weill,B., DinhXuan,A.T. and Batteux,F.d.r. (2013) Amelioration of Systemic Fibrosis in Mice by Angiotensin II Receptor Blockade. Arthritis & Rheumatism, 65, 1367-1377.

Microfabricated Scaffolds Cultivated with Fibroblasts

Masoumi,N., Jean,A.l., Zugates,J.T., Johnson,K.L. and Engelmayr,G.C. (2013) Laser microfabricated poly (glycerol sebacate) scaffolds for heart valve tissue engineering. Journal of Biomedical Materials Research Part A, 101, 104-114.

Porcine Aortic and Pulmonary Valvular Interstitial Cells

Masoumi,N., Johnson,K.L., Howell,M.C. and Engelmayr Jr,G.C. (2013) Valvular interstitial cell seeded poly (glycerol sebacate) scaffolds: Toward a biomimetic in vitro model for heart valve tissue engineering. Acta Biomaterialia 9, 5974 – 5988.

Rat Skin Fibroblasts

Masoumi,N., Jean,A.l., Zugates,J.T., Johnson,K.L. and Engelmayr,G.C. (2013) Laser microfabricated poly (glycerol sebacate) scaffolds for heart valve tissue engineering. Journal of Biomedical Materials Research Part A, 101, 104-114.

Dermal Fibroblasts and Murine Skin

Maurer,B., Distler,A., Suliman,Y.A., Gay,R.E., Michel,B.A., Gay,S., Distler,J.H. and Distler,O. (2013) Vascular endothelial growth factor aggravates fibrosis and vasculopathy in experimental models of systemic sclerosis. Annals of the rheumatic diseases, doi: 10.1136/annrheumdis-2013-203535.

Rat Lung

Miranda,L.F., Rodrigues,C.O., Ramachandran,S., Torres,E., Huang,J., Klim,J., Hehre,D., McNiece,I., Hare,J.M. and Suguihara,C.Y. (2013) Stem cell factor improves lung recovery in rats following neonatal hyperoxia-induced lung injury. Pediatric research 74, 682 – 688.

Porcine Pancreas

Mirmalek-Sani,S.H., Orlando,G., McQuilling,J., Pareta,R., Mack,D., Salvatori,M., Farney,A.C., Stratta,R.J., Atala,A. and Opara,E.C. (2013) Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering. Biomaterials 34, 5488 – 5495.

Murine Lung

Miyamoto,K., Tasaka,S., Nakano,Y., Shinoda,H., Kamata,H., Yamasawa,W., Ishii,M., Hasegawa,N. and Betsuyaku,T. (2013) Differential Mechanisms of the Effect of Peroxisome Proliferator-Activated Receptor Gamma Agonists on Bleomycin-Induced Lung Fibrosis. Oopen Journal of Respiratory Diseases 3, 31 – 38.

Murine Lung

Mizutani,N., Nabe,T. and Yoshino,S. (2013) InterleukinÇÉ33 and alveolar macrophages contribute to the

mechanisms underlying the exacerbation of IgEmediated airway inflammation and remodelling in mice. Immunology, 139, 205-218.

Undetermined Model

Moeinzadeh,S., Barati,D., Sarvestani,S.K., Karaman,O. and Jabbari,E. (2013) Nanostructure Formation and Transition from Surface to Bulk Degradation in Polyethylene Glycol Gels Chain-Extended with Short Hydroxy Acid Segments. Biomacromolecules, 14, 2917-2928.

Nasal Polyp-Derived Fibroblasts

Moon,Y., Park,I., Cho,J., Um,J., Kim,T.H. and Lee,H. (2013) Berberine Inhibits Myofibroblast Differentiation in

Nasal PolypDerived Fibroblasts via the p38 Pathway. Phytotherapy Research, 27, 16-20.

Vascular Smooth Muscle Cells

Mun,C.H., Jung,Y., Kim,S., Kim,H.C. and Kim,S.H. (2013) Effects of Pulsatile Bioreactor Culture on Vascular Smooth

Muscle Cells Seeded on Electrospun Poly (lactidecoεcaprolactone) Scaffold. Artificial Organs 37, E168 – E178.

Tiger Temporomandibular Disc

Murphy,M.K., Arzi,B., Vapniarsky-Arzi,N. and Athanasiou,K.A. (2013) Characterization of Degenerative Changes in the Temporomandibular Joint of the Bengal Tiger (Panthera tigris tigris) and Siberian Tiger (Panthera tigris altaica). Journal of comparative pathology, 149, 495-502.

Porcine Costochondral Cells

Murphy,M.K., Huey,D.J., Reimer,A.J., Hu,J.C. and Athanasiou,K.A. (2013) Enhancing Post-Expansion Chondrogenic Potential of Costochondral Cells in Self-Assembled Neocartilage. PloS one, 8, e56983.

Tissue Engineered Vascular Graft

Naito,Y., Lee,Y.U., Yi,T., Church,S.N., Solomon,D., Humphrey,J.D., Shin'oka,T. and Breuer,C.K. (2013) Beyond Burst Pressure: Initial Evaluation of the Natural History of the Biaxial Mechanical Properties of Tissue-Engineered Vascular Grafts in the Venous Circulation Using a Murine Model. Tissue Engineering Part A. doi: 10.1089/ten.tea.2012.0613.

Polycystic Kidney Rat and Biliary Epithelial Cells (Cholangiocytes)

Nakanuma,Y., Sato,Y. and Harada,K. (2013) Tissue Culture Correlational Study of Genetic Cholangiopathy of Autosomal Recessive Polycystic Kidney Disease. Epithelial Cell Culture Protocols. Methods in Molecular Biology 945, 303 – 318.

Rabbit Adipose Tissue-Derived Mesenchymal Stem Cells

Neo,P.Y., See,E.Y., Toh,S.L. and Goh,J.C. (2013) Temporal profiling of the growth and multilineage potentiality of

adipose tissuederived mesenchymal stem cells cellsheets. Journal of tissue engineering and regenerative medicine, doi: 10.1002/term.1776.

Murine Cardiac Fibroblasts

Novoyatleva,T., Schymura,Y., Janssen,W., Strobl,F., Swiercz,J.M., Patra,C., Posern,G., Wietelmann,A., Zheng,T.S. and Schermuly,R.T. (2013) Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction. Basic research in cardiology, 108, 1-13.

Decellularised Porcine Ileum

Nowocin,A.K., Southgate,A., Shurey,S., Sibbons,P., Gabe,S.M. and Ansari,T. (2013) The development and implantation of a biologically derived allograft scaffold. Journal of tissue engineering and regenerative medicine, doi: 10.1002/term.1722.

Human and Porcine Lung Tissue

O'Neill,J.D., Anfang,R., Anandappa,A., Costa,J., Javidfar,J., Wobma,H.M., Singh,G., Freytes,D.O., Bacchetta,M.D. and Sonett,J.R. (2013) Decellularization of human and porcine lung tissues for pulmonary tissue engineering. The Annals of thoracic surgery, 96, 1046-1056.

Kidney Sheets/Digests

O'Neill,J.D., Freytes,D.O., Anandappa,A.J., Oliver,J.A. and Vunjak-Novakovic,G.V. (2013) The regulation of growth and metabolism of kidney stem cells with regional specificity using extracellular matrix derived from kidney. Biomaterials, 34, 9830-9841.

Primary Rat Osteoblasts

Orriss,I.R., Key,M.L., Hajjawi,M.O. and Arnett,T.R. (2013) Extracellular ATP Released by Osteoblasts Is A Key Local Inhibitor of Bone Mineralisation. PloS one, 8, e69057.

Ovine Nasoseptal Chondrocytes

Oseni,A.O., Butler,P.E. and Seifalian,A.M. (2013) The application of POSS nanostructures in cartilage tissue engineering: the chondrocyte response to nanoscale geometry. Journal of tissue engineering and regenerative medicine, doi: 10.1002/term.1693.

Murine Lung

Park,B.S., Hong,G.U. and Ro,J.Y. (2013) Foxp3+-Treg Cells Enhanced by Repeated Low-Dose Gamma-Irradiation Attenuate Ovalbumin-Induced Allergic Asthma in Mice. Radiation research, 179, 570-583.

Human Hepatic Stellate LX-2 Cells

Park,S.J., Sohn,H.Y. and Park,S.I. (2013) TRAIL Regulates Collagen Production through HSF1-dependent Hsp47 Expression in Activated Hepatic Stellate Cells. Cellular signalling 25, 1635 – 1643.

Fibroblasts

Park,S.J., Jun,Y.J., Kim,T.H., Jung,J.Y., Hwang,G.H., Jung,K.J., Lee,S.H., Lee,H.M. and Lee,S.H. (2013) Increased expression of YKL-40 in mild and moderate/severe persistent allergic rhinitis and its possible contribution to remodeling of nasal mucosa. American Journal of Rhinology & Allergy, 27, 372-380.

Chondrocytes

Park,Y.J. and Kim,J.K. (2013) The Effect of Negative Poisson’s Ratio Polyurethane Scaffolds for Articular Cartilage Tissue Engineering Applications. Advances in Materials Science and Engineering, http://dx.doi.org/10.1155/2013/853289.

Native Trachea

Partington,L., Mordan,N.J., Mason,C., Knowles,J.C., Kim,H.W., Lowdell,M.W., Birchall,M.A. and Wall,I. (2013) Biochemical changes caused by decellularization may compromise mechanical integrity of tracheal scaffolds. Acta Biomaterialia 9, 5251 – 5261.

Human Trabecular Meshwork Cells

Pattabiraman,P.P., Maddala,R. and Rao,P.V. (2013) Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling. Journal of Cellular Physiology doi: 10.1002/jcp.24524.

Engineered Collagen Fibres

Paten,J.A., Tilburey,G.E., Molloy,E.A., Zareian,R., Trainor,C.V. and Ruberti,J.W. (2013) Utility of an optically-based, micromechanical system for printing collagen fibers. Biomaterials 34, 2577 – 2587.

Human Aorta

Phillippi,J.A., Green,B.R., Eskay,M.A., Kotlarczyk,M.P., Hill,M.R., Robertson,A.M., Watkins,S.C., Vorp,D.A. and Gleason,T.G. (2013) Mechanism of aortic medial matrix remodeling is distinct in patients with bicuspid aortic valve. The Journal of thoracic and cardiovascular surgery, doi: 10.1016/j.jtcvs.2013.04.028.

Human Mesenchymal Stem Cells

Prewitz,M.C., Seib,F.P., von Bonin,M., Friedrichs,J., Sti+el,A., Niehage,C., Müller,K., Anastassiadis,K., Waskow,C. and Hoflack,B. (2013) Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments. Nature methods 10, 788 – 794.

Rat Cardiac Fibroblasts

Purnomo,Y., Piccart,Y., Coenen,T., van Pelt,J., Prihadi,J.S. and Lijnen,P.J. (2013) Oxidants and Antioxidants in Medical Science 2, 5 – 10.

Cardiac Progenitor Cells

Rajabi-Zeleti,S., Jalili-Firoozinezhad,S., Azarnia,M., Khayyatan,F., Vahdat,S., Nikeghbalian,S., Khademhosseini,A., Baharvand,H. and Aghdami,N. (2014) The behavior of cardiac progenitor cells on macroporous pericardium-derived scaffolds. Biomaterials, 35, 970-982.

Murine and Human Lung

Reilkoff,R.A., Peng,H., Murray,L.A., Peng,X., Russell,T., Montgomery,R., Feghali-Bostwick,C., Shaw,A., Homer,R.J. and Gulati,M. (2013) Semaphorin 7a+ Regulatory T Cells Are Associated with Progressive Idiopathic

Pulmonary Fibrosis and Are Implicated in Transforming Growth Factor-+¦1Çôinduced Pulmonary Fibrosis. American journal of respiratory and critical care medicine, 187, 180-188.

Primary Human Dermal Fibroblasts

Remoué,N.l., Molinari,J., Andres,E., Lago,J.C., Barrichello,C. and Moreira,P.L. (2013) Development of an in vitro model of menopause using primary human dermal fibroblasts. International journal of cosmetic science, 35, 546-554.

Mouse Respiratory Tract

Ronzani,C., Casset,A. and Pons,F. (2013) Exposure to multi-walled carbon nanotubes results in aggravation of airway inflammation and remodeling and in increased production of epithelium-derived innate cytokines in a mouse model of asthma. Archives of toxicology, doi: 10.1007/s00204-013-1116-3.

Primary Human Airway Smooth Muscle Cells

Roth,M., Zhong,J., Zumkeller,C., S’ng,C.T., Goulet,S. and Tamm,M. (2013) The Role of IgE-Receptors in IgE-Dependent Airway Smooth Muscle Cell Remodelling. PloS one, 8, e56015.

Murine Lung

Rothemund,S., Sönnichsen,F.D. and Polte,T. (2013) Therapeutic Potential of the Peptide Leucine Arginine As a New

Nonplant BowmanBirk-Like Serine Protease Inhibitor. Journal of medicinal chemistry, 56, 6732-6744.

Murine Lung

Ruiz,D.B., D'Alessandro-Gabazza,C.N., Toda,M., Takagi,T., Naito,M., Matsushima,Y., Matsumoto,T., Kobayashi,T., Gil-Bernabe,P. and Chelakkot-Govindalayathil,A.L. (2013) Differential Role of Regulatory T Cells in Early and Late Stages of Pulmonary Fibrosis. Immunobiology 218, 245 – 254.

Rat Pancreatic Stellate Cells

Ryu,G.R., Lee,E., Chun,H.J., Yoon,K.H., Ko,S.H., Ahn,Y.B. and Song,K.H. (2013) Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells. Biochemical and biophysical research communications, 439, 258-263.

Murine Lung

Saglani,S., Lui,S., Ullmann,N., Campbell,G.A., Sherburn,R.T., Mathie,S.A., Denney,L., Bossley,C.J., Oates,T. and Walker,S.A. (2013) IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. Journal of Allergy and Clinical Immunology 132, 676 – 685.e13.

Murine Lung

Sakai,M., Kubota,T., Ohnishi,H. and Yokoyama,A. (2013) A Novel Lung Injury Animal Model Using KL-6-Measurable Human MUC1-Expressing Mice. Biochemical and Biophysical Research Communications 432, 460 – 465.

Murine Lung

Sayers,B.C., Taylor,A.J., Glista-Baker,E.E., Shipley-Phillips,J.K., Dackor,R.T., Edin,M.L., Lih,F.B., Tomer,K.B., Zeldin,D.C. and Langenbach,R. (2013) Role of COX-2 in Exacerbation of Allergen-Induced Airway Remodeling by Multi-Walled Carbon Nanotubes. American Journal of Respiratory Cell and Molecular Biology 49, 525 – 535.

Murine Lung

Scotton,C.J., Hayes,B., Alexander,R., Datta,A., Forty,E.J., Mercer,P.F., Blanchard,A. and Chambers,R.C. (2013) Ex vivo μCT analysis of bleomycin-induced lung fibrosis for pre-clinical drug evaluation. European Respiratory Journal, doi: 10.1183/09031936.00182412.

Pleural Mesothelial Cells

Serve,K.M., Black,B., Szeinuk,J. and Pfau,J.C. (2013) Asbestos-associated mesothelial cell autoantibodies promote collagen deposition in vitro. Inhalation Toxicology, 25, 774-784.

Cartilage Scaffold Analogs

Sharma,S., Panitch,A. and Neu,C.P. (2013) Incorporation of an Aggrecan Mimic Prevents Proteolytic Degradation of Anisotropic Cartilage Analogs. Acta Biomaterialia 9, 4618 – 4625.

Adult Mouse Cardiac Fibroblasts

Siddesha,J.M., Valente,A.J., Sakamuri,S.S., Yoshida,T., Gardner,J.D., Somanna,N., Takahashi,C., Noda,M. and Chandrasekar,B. (2013) Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK. Journal of molecular and cellular cardiology, 65, 9-18.

Human Breast Cancer Cells (HMLER)

Simic,P., Williams,E.O., Bell,E.L., Gong,J.J., Bonkowski,M. and Guarente,L. (2013) SIRT1 Suppresses the Epithelial-to-Mesenchymal Transition in Cancer Metastasis and Organ Fibrosis. Cell reports 3, 1175 – 1186.

Mouse Fibroblast L929 Cells and Human Keratinocyte Cell Line (HaCat)

Siritientong,T., Ratanavaraporn,J., Srichana,T. and Aramwit,P. (2013) Preliminary Characterization of Genipin-Cross-Linked Silk Sericin/Poly (vinyl alcohol) Films as Two-Dimensional Wound Dressings for the Healing of Superficial Wounds. BioMed Research International, http://dx.doi.org/10.1155/2013/904314.

Human Dermal Fibroblasts

Slominski,A., Janjetovic,Z., Tuckey,R.C., Nguyen,M.N., Bhattacharya,K.G., Wang,J., Li,W., Jiao,Y., Gu,W. and Brown,M. (2013) 20S-Hydroxyvitamin D3, Noncalcemic Product of CYP11A1 Action on Vitamin D3, Exhibits Potent Antifibrogenic Activity in Vivo. Journal of Clinical Endocrinology & Metabolism, 98, E298-E303.

Decellularised Rat, Porcine and Human Kidneys

Song,J.J., Guyette,J.P., Gilpin,S.E., Gonzalez,G., Vacanti,J.P. and Ott,H.C. (2013) Regeneration and experimental orthotopic transplantation of a bioengineered kidney. Nature medicine, 19, 646-651.

Human Osteosarcoma-Derived Osteoblasts (MG63)

Stoppato,M., Carletti,E., Sidarovich,V., Quattrone,A., Unger,R.E., Kirkpatrick,C.J., Migliaresi,C. and Motta,A. (2013) Influence of scaffold pore size on collagen I development: A new in vitro evaluation perspective. Journal of Bioactive and Compatible Polymers, 28, 16-32.

Human Mesenchymal Stem Cells

Subramony,S.D., Su,A., Yeager,K. and Lu,H.H. (2013) Combined effects of chemical priming and mechanical stimulation on mesenchymal stem cell differentiation on nanofiber scaffolds. Journal of Biomechanics, http://dx.doi.org/10.1016/j.jbiomech.2013.10.016.

Murine Macrophage RAW264.7 Cells and Mouse Fibroblast L929 Cells

Sudsai,T., Wattanapiromsakul,C., Nakpheng,T. and Tewtrakul,S. (2013) Evaluation of the wound healing property of Boesenbergia longiflora rhizomes. Journal of Ethnopharmacology, 150, 223-231.

Mouse Osteoblastic Cell Line (MC3T3-E1)

Suh,K.S., Rhee,S.Y., Jung,W.W., Kim,N.J., Jang,Y.P., Kim,H.J., Kim,M.K., Choi,Y.K. and Kim,Y.S. (2013) Chrysanthemum zawadskii extract protects osteoblastic cells from highly reducing sugar-induced oxidative damage. International journal of molecular medicine, 32, 241.

Rat Lung

Sung,D.K., Kong,W.H., Park,K., Kim,J.H., Kim,M.Y., Kim,H. and Hahn,S.K. (2012) Noncovalenly PEGylated CTGF siRNA/PDMAEMA complex for pulmonary treatment of bleomycin-induced lung fibrosis. Biomaterials 34, 1261 – 1269.

Murine Lung

Sunaga,H., Matsui,H., Ueno,M., Maeno,T., Iso,T., Syamsunarno,M.R.A., Anjo,S., Matsuzaka,T., Shimano,H. and Yokoyama,T. (2013) Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice. Nature communications, doi:10.1038/ncomms3563.

Murine Skin Fibroblast Scratch Wound

Tam,K., Suganya,C., Venugopal,J., Biswas,A., Choolani,M., Ramakrishna,S., Bongso,A. and Fong,C. (2013) A Nanoscaffold Impregnated with Human Wharton's Jelly Stem Cells or Its Secretions Improves Healing of Wounds. Journal of Cellular Biochemistry, doi: 10.1002/jcb.24723.

Human Fibrotic Livers

Tan,Z., Qian,X., Jiang,R., Liu,Q., Wang,Y., Chen,C., Wang,X., Ryffel,B. and Sun,B. (2013) IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. The Journal of Immunology, 191, 1835-1844.

Murine Lung

Tang,N., Zhao,Y., Feng,R., Liu,Y., Wang,S., Wei,W., Ding,Q., An,M.S., Wen,J. and Li,L. (2013) Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts. Journal of cellular and molecular medicine, doi: 10.1111/jcmm.12178.

Human Scleral Fibroblasts

Tao,Y., Pan,M., Liu,S., Fang,F., Lu,R., Lu,C., Zheng,M., An,J., Xu,H. and Zhao,F. (2013) cAMP Level Modulates Scleral Collagen Remodeling, a Critical Step in the Development of Myopia. PloS one, 8, e71441.

Mesenchymal Stem Cells

Teh,T.K., Toh,S.L. and Goh,J.C. (2013) Aligned Fibrous Scaffolds for Enhanced Mechanoresponse and Tenogenesis of Mesenchymal Stem Cells. Tissue Engineering Part A, 19, 1360-1372.

Murine Primary Calvarial Osteoblasts

Thiele,F., Cohrs,C.M., Przemeck,G.K., Wurst,W., Fuchs,H. and de Angelis,M.H. (2013) In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system. Journal of bone and mineral metabolism, 31, 293 – 303.

Vascular Smooth Muscle Cells

Thomas,L.V. and Nair,P.D. (2013) The Effect of Pulsatile Loading and Scaffold Structure for the Generation of a Medial Equivalent Tissue Engineered Vascular Graft. BioResearch open access, 2, 227-239.

Human Adipose Stem Cells

Tirkkonen,L., Haimi,S., Huttunen,S., Wolff,J., Pirhonen,E., S+índor,G.K. and Miettinen,S. (2013) Osteogenic medium is superior to growth factors in differentiation of human adipose stem cells towards bone-forming cells in 3D culture. European Cells and Materials, 25, 144 – 158.

Murine Skin and Cultured Fibroblasts

Tomcik,M., Zerr,P., Pitkowski,J., Palumbo-Zerr,K., Avouac,J., Distler,O., Becvar,R., Senolt,L., Schett,G. and Distler,J.H. (2013) Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis. Annals of the rheumatic diseases, doi: 10.1136/annrheumdis-2012-203095.

Human Lung Fibroblasts

Tseng,C.M., Hsiao,Y.H., Su,V.Y.-F., Su,K.C., Wu,Y.C., Chang,K.T. and Perng,D.W. (2013) The Suppression Effects of Thalidomide on Human Lung Fibroblasts: Cell Proliferation, Vascular Endothelial Growth Factor Release, and Collagen Production. Lung 191, 361 - 368.

Murine Lung Upper Right Lobe

Tully,J.E., Hoffman,S.M., Lahue,K.G., Nolin,J.D., Anathy,V., Lundblad,L.K., Daphtary,N., Aliyeva,M., Black,K.E.

and Dixon,A.E. (2013) Epithelial NF-κB Orchestrates House Dust MiteInduced Airway Inflammation, Hyperresponsiveness, and Fibrotic Remodeling. The Journal of Immunology, 191, 5811-5821.

Murine Primary Cardiac Fibroblasts

Valente,A.J., Sakamuri,S.S., Siddesha,J.M., Yoshida,T., Gardner,J.D., Prabhu,R., Siebenlist,U. and Chandrasekar,B. (2013) TRAF3IP2 mediates interleukin-18-induced cardiac fibroblast migration and differentiation. Cellular signalling, 25, 2176-2184.

Murine Lung

Veerappan,A., O'Connor,N.J., Brazin,J., Reid,A.C., Jung,A., McGee,D., Summers,B., Branch-Elliman,D., Stiles,B. and Worgall,S. (2013) Mast Cells: A Pivotal Role in Pulmonary Fibrosis. DNA and cell biology, 32, 206-218.

Murine Lung

Walters,D.M., White,K.M., Patel,U., Davis,M.J., Veluci-Marlow,R.M., Sunkesula,S.R.B., Bonner,J.C., Martin,J.R., Gladwell,W. and Kleeberger,S.R. (2013) Genetic susceptibility to interstitial pulmonary fibrosis in mice induced by vanadium pentoxide (V2O5). The FASEB Journal, doi: 10.1096/fj.13-235044.

Rat Tail Intervertebral Discs

Wang,I.C., Liu,H.T., Yu,C.M., Whu,S.W., Lin,S.S., Su,C.I., Chen,C.H. and Chen,W.J. (2013) Effect of hyperbaric oxygenation on intervertebral disc degeneration: An in vivo study with Sprague-Dawley rats. Spine, 38, E137-E142.

Lung Tissue

Wang,X., Ji,Z., Chang,C.H., Zhang,H., Wang,M., Liao,Y., Lin,S., Meng,H., Li,R. and Sun,B. (2013) Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential. Small, doi: 10.1002/smll.201301597.

White Rabbit Bone Marrow Mesenchymal Stem Cells

Wei,B., Jin,C., Xu,T., Tang,C., Hu,W. And Wang.L. (2013) Effect of Bone Marrow Besenchymal Stem Cells-Derived extracellular Matrix Scaffold on Chondrogenic Differentiation of Marrow Clot after Microfracture of Bone Marrow stimulation In Vitro. Chinese Journal of Reparative and Reconstructive Surgery, 27, 464.

Human Myometrial Biopsy Samples

Wendremaire,M., Mourtialon,P., Goirand,F., Lirussi,F.d.r., Barrichon,M., Hadi,T., Garrido,C., Le Ray,I., Dumas,M. and Sagot,P. (2013) Effects of Leptin on Lipopolysaccharide-Induced Remodeling in an In Vitro Model of Human Myometrial Inflammation 1. Biology of Reproduction, 88, Article 45, 1 – 10.

Horse Lung

Williams,K.J., Robinson,N.E., Lim,A., Brandenberger,C., Maes,R., Behan,A. and Bolin,S.R. (2013) Experimental Induction of Pulmonary Fibrosis in Horses with the Gammaherpesvirus Equine Herpesvirus 5. PloS one, 8, e77754.

Human Lung Fibroblasts

Wu,C.S., Hsu,Y.C., Yeh,J.t., Liao,H.T., Jhang,J.J. and Sie,Y.Y. (2013) Biocompatibility and characterization of renewable agricultural residues and polyester composites. Carbohydrate Polymers 94, 584 – 593.

Human Foreskin Fibroblasts

Wu,C.S. and Liao,H.T. (2013) The mechanical properties, biocompatibility and biodegradability of chestnut shell fibre and polyhydroxyalkanoate composites. Polymer Degradation and Stability, http://dx/dpo/prg/10.1016/j.polymdegradstab.2013.10.019.

Osteoprogenitor MC3T3-E1 Cells

Wu,L.C., Liu,H.W., Chen,C.K., Kuo,J.T., Chou,H.K. and Chung,Y.C. (2013) The Effect on a New Sintered Calcium Sulfate Ceramic to Osteoprogenitor MC 3T3-E1. Advanced Materials Research, 677, 201-206.

Murine Skin

Wu,M., Pedroza,M., Lafyatis,R., George,A., Mayes,M.D., Assassi,S., Tan,F.K., Brenner,M.B. and Agarwal,S.K. (2013)

Identification of cadherin11 as a mediator of dermal fibrosis and possible role in systemic sclerosis. Arthritis & Rheumatism, doi:10.1002/art.38275.

Lung

Xi,Y., Tan,K., Brumwell,A.N., Chen,S., Kim,Y.H., Kim,T.J., Wei,Y. and Chapman,H.A. (2013) Inhibition of Epithelial to Mesenchymal Transition and Pulmonary Fibrosis by Methacycline. American Journal of Respiratory Cell and Molecular Biology, http://www.atsjournals.org/doi/abs/10.1165/rcmb.2013-00990c.

Human Lung Fibroblasts (HFL-1)

Yang,M., Zhao,X., Liu,Y., Tian,Y., Ran,X. and Jiang,Y. (2013) A role for WNT1-inducible signaling protein-1 in airway remodeling in a rat asthma model. International immunopharmacology 17, 350 – 357.

Murine Lung

Yang,S., Cui,H., Xie,N., Icyuz,M., Banerjee,S., Antony,V.B., Abraham,E., Thannickal,V.J. and Liu,G. (2013) miR-145 regulates myofibroblast differentiation and lung fibrosis. The FASEB Journal, 27, 2382-2391.

Murine Lung

Yee,M., Buczynski,B.W., Lawrence,B.P. and O'Reilly,M.A. (2013) Neonatal Hyperoxia Increases Sensitivity of Adult Mice to Bleomycin-Induced Lung Fibrosis. American Journal of Respiratory Cell and Molecular Biology, 48, 258-266.

Rat Lung

Yoo,H.S., Chang,Y.S., Kim,J.K., Ahn,S.Y., Kim,E.S., Sung,D.K., Jeon,G.W., Hwang,J.H., Shim,J.W. and Park,W.S. (2013) Antenatal betamethasone attenuates intrauterine infection-aggravated hyperoxia-induced lung injury in neonatal rats. Pediatric research, 73, 726-733.

Anterior Cruciate Ligament on Three-Dimensional Collagen Scaffolds

Yoshida,R. and Murray,M.M. (2013) Peripheral blood mononuclear cells enhance the anabolic effects of plateletrich plasma on anterior cruciate ligament fibroblasts. Journal of Orthopaedic Research, 31, 29-34.

Equine Tendons

Youngstrom,D.W., Barrett,J.G., Jose,R.R. and Kaplan,D.L. (2013) Functional Characterization of Detergent-Decellularized Equine Tendon Extracellular Matrix for Tissue Engineering Applications. PloS one, 8, e64151.

Anterior Cruciate Ligament Fibroblasts

Yoshida,R. and Murray,M.M. (2013) Peripheral blood mononuclear cells enhance the anabolic effects of plateletrich plasma on anterior cruciate ligament fibroblasts. Journal of Orthopaedic Research, 31, 29-34.

Murine Colon Tissue

Yuan,C., Chen,W.X., Zhu,J.S., Chen,N.W., Lu,Y.M., Ou,Y.X. and Chen,H.Q. (2013) IL-10 Treatment Is Associated with Prohibitin Expression in the Crohn’s Disease Intestinal Fibrosis Mouse Model. Mediators of inflammation, http://dx.doi.org/10.1155/2013/617145.

Human Noduels of Fibroblasts from Duchenne Muscular Dystrophy Muscle

Zanotti,S., Gibertini,S., Savadori,P., Mantegazza,R. and Mora,M. (2013) Duchenne muscular dystrophy fibroblast nodules: a cell-based assay for screening anti-fibrotic agents. Cell and tissue research, 352, 659 - 670.

Rat Cardiac Tissue

Zhang,H., Zhong,H., Everett IV,T.H., Wilson,E., Chang,R., Zeng,D., Belardinelli,L. and Olgin,J.E. (2013) Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias one week after myocardial infarction in the rat model. Heart Rhythm, http://dx.doi.org/10.1016/j.hrthm.2013.10.023.

Murine Lung

Zhou,Y., Kang,M.J., Jha,B.K., Silverman,R.H., Lee,C.G. and Elias,J.A. (2013) Role of Ribonuclease L in Viral

Pathogen-Associated Molecular Pattern/Influenza Virus and Cigarette SmokeInduced Inflammation and Remodeling. The Journal of Immunology, 191, 2637-2646.

Neonatal Rat Ventricular Cardiomyocytes and Cardiac Fibroblasts

Zhu,W., Zhao,Y., Xu,Y., Sun,Y., Wang,Z., Yuan,W. and Du,Z. (2013) Dissection of Protein Interactomics Highlights MicroRNA Synergy. PloS one, 8, e63342.

Murine Embryonic Fibroblasts (MEFs) and Rat and Human Idiopathic Pulmonary Fibrosis Lung Fibroblasts

Zimmerman,K.A., Graham,L.V., Pallero,M.A. and Murphy-Ullrich,J.E. (2013) Calreticulin Regulates Transforming Growth Factor-β-stimulated Extracellular Matrix Production. Journal of Biological Chemistry, 288, 14584-14598.

Murine Lung

Ziobro,R., Henry,B., Edwards,M.J., Lentsch,A.B. and Gulbins,E. (2013) Ceramide mediates lung fibrosis in cystic fibrosis. Biochemical and biophysical research communications 434, 705 – 709.

Primary Human Colonic Myofibroblast Cell Line (CCD-18Co Cells)

Ziogas,D.C., Gras-Miralles,B., Mustafa,S., Geiger,B.M., Najarian,R.M., Nagel,J.M., Flier,S.N., Popov,Y., Tseng,Y.H. and Kokkotou,E. (2013) Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 304, G876-G884.

2012

Human Fibroblasts

Akhmetshina,A., Palumbo,K., Dees,C., Bergmann,C., Venalis,P., Zerr,P., Horn,A., Kireva,T., Beyer,C. and Zwerina,J. (2012) Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nature Communications, 3, 735.

Human Mesenchymal Stem Cells

Alvarez Perez,M.A., Guarino,V., Cirillo,V. and Ambrosio,L. (2012) In vitro mineralization and bone osteogenesis in poly ε-caprolactone)/gelatin nanofibers. Journal of Biomedical Materials Research Part A, doi: 10.1002/jbm.a.34233.

Murine Lung

Anathy,V., Roberson,E., Cunniff,B., Nolin,J., Hoffmann,S., Spiess,P., Guala,A.S., Lahue,K., Goldman,D. and Flemer,S. (2012) Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Molecular and Cellular Biology, 32, 3464 - 3478.

Articular Cartilage Tissue

Antipova,O. and Orgel,J.P.R.O. (2012) Non-Enzymatic Decomposition of Collagen Fibers by a Biglycan Antibody and a Plausible Mechanism for Rheumatoid Arthritis. PLoS ONE, 7, e32241.

Rat Lung Tissue

Aoki,Y., Kojo,Y., Yamada,S. and Onoue,S. (2012) Respirable dry powder formulation of bleomycin for developing a pulmonary fibrosis animal model. Journal of Pharmaceutical Sciences, 101, 2074 - 2081.

Murine Lung Tissue

Aono,Y., Ledford,J.G., Mukherjee,S., Ogawa,H., Nishioka,Y., Sone,S., Beers,M.F., Noble,P.W. and Wright,J.R. (2012) Surfactant Protein-D Regulates Effector Cell Function and Fibrotic Lung Remodeling in Response to Bleomycin Injury. American Journal of Respiratory and Critical Care Medicine, 185, 525-536.

Undetermined Model

Azad,N., Iyer,A.K.V., Wang,L., Liu,Y., Lu,Y. and Rojanasakul,Y. (2012) Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses. Nanotoxicology, doi: 10.3109/17435390.2011.647929.

Human Colon Adenocarcinoma Cell Line (SW480)

Baker,A.M., Bird,D., Lang,G., Cox,T.R. and Erler,J.T. (2012) Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. Oncogene, doi: 10.1038/onc.2012.202.

Porcine Aortic Valve Cusps

Balachandran,K., Hussain,S., Yap,C.H., Padala,M., Chester,A.H. and Yoganathan,A.P. (2012) Elevated cyclic stretch and serotonin result in altered aortic valve remodeling via a mechanosensitive 5-HT2Areceptor-dependent pathway. Cardiovascular Pathology, 21, 206-213.

Murine Fibroblast Cell Line (L929 Cells)

Balekar,N., Katkam,N.G., Nakpheng,T., Jehtae,K. and Srichana,T. (2012) Evaluation of the wound healing potential of Wedelia trilobata (L.) leaves. Journal of Ethnopharmacology, 141, 817 – 824.

Murine Lung

Banerjee,E.R., Laflamme,M.A., Papayannopoulou,T., Kahn,M., Murry,C.E. and Henderson,W.R. (2012) Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model. PloS one, 7, e33165.

Murine Lung

Banerjee,E.R. and Henderson,W.R. (2012) Characterization of lung stem cell niches in a mouse model of bleomycin-induced fibrosis. Stem Cell Research & Therapy, 3, 21.

Murine Lung

Banerjee,E.R., Laflamme,M.A., Papayannopoulou,T., Kahn,M., Murry,C.E. and Henderson,W.R. (2012) Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model. PLoS One, 7, e33165.

Fibroblasts

Bhattacharyya,S., Kelley,K., Melichian,D., Tamaki,Z., Fang,F., Su,Y., Feng,G., Pope,R.M., Budinger,G.R. and Mutlu,G.M. (2012) Toll-Like Receptor 4 Signaling Augments Transforming Growth Factor-β Responses: A Novel Mechanism for Maintaining and Amplifying Fibrosis in Scleroderma. The American journal of pathology 182, 192 – 205.

Human Dermal Fibroblasts

Beyer,C., Reich,N., Schindler,S.C., Akhmetshina,A., Dees,C., Tomcik,M., Hirth-Dietrich,C., von Degenfeld,G., Sandner,P. and Distler,O. (2012) Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis. Annals of the Rheumatic Diseases, 71, 1019 - 1026.

Fibroblasts and Lung Tissue

Bolaños,A.L., Milla,C.M., Lira,J.C., Ram+¡rez,R., Checa,M., Barrera,L., García-Alvarez,J., Carbajal,V., Becerril,C. and Gaxiola,M. (2012) Role of Sonic Hedgehog in idiopathic pulmonary fibrosis. American Journal of Physiology-Lung Cellular and Molecular Physiology, 303, L978-L990.

Human Dermal Decellularised Membrane

Bondioli,E., Fini,M., Veronesi,F., Giavaresi,G., Tschon,M., Cenacchi,G., Cerasoli,S., Giardino,R. and Melandri,D. (2012) Development and evaluation of a decellularized membrane from human dermis. Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.1530.

Murine Lung

Bönisch,U., Böhme,A., Kohajda,T., Mögel,I., Schütze,N., von Bergen,M., Simon,J.C., Lehmann,I. and Polte,T. (2012) Volatile Organic Compounds Enhance Allergic Airway Inflammation in an Experimental Mouse Model. PloS one, 7, e39817.

Murine Lung

Buczynski,B.W., Yee,M., Paige Lawrence,B. and O'Reilly,M.A. (2012) Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice. American Journal of Physiology-Lung Cellular and Molecular Physiology, 302, L1078-L1087.

Adipose Tissue Derived Mesenchymal Stem Cells

Carvalho,L.R.P., Breyner,N.M., Hell,R.C.R., Valério,P., Novikoff,S. and Goes,A.M. (2012) Healing Pattern in Calvarial Bone Defects Following Bone Regeneration in Rats Guided by Chitosan Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells. Open Tissue Engineering and Regenerative Medicine Journal, 5, 25-34.

Rat Cardiac Fibroblasts and Myofibroblasts

Catalán,M., Smolic,C., Contreras,A., Ayala,P., Olmedo,I., Copaja,M., Boza,P., Vivar,R., Avalos,Y. and Lavandero,S. (2012) Differential regulation of collagen secretion by kinin receptors in cardiac fibroblast and myofibroblast. Toxicology and Applied Pharmacology 261, 300 – 308.

Murine Skeletal Muscle Fibroblasts (NOR-10) and Myoblasts (C2C12) Cells

Cha,M.C. and Purslow,P.P. (2012) Expressions of matrix metalloproteinases and their inhibitor are modified by beta-adrenergic agonist Ractopamine in skeletal fibroblasts and myoblasts. Canadian Journal of Animal Science, 92, 159 - 166.

Mouse Cardiac Fibroblasts

Chan,E.C., Peshavariya,H.M., Liu,G.S., Jiang,F., Lim,S.Y. and Dusting,G.J. (2012) Nox4 modulates collagen production stimulated by transforming growth factor β1 in vivo and in vitro. Biochemical and Biophysical Research Communications, http://dx.doi.org/10.1016/j.bbrc.2012.11.138.

Rabbit Tibia Periosteal Progenitor Cells

Chang,C., Chen,C., Liu,H., Whu,S., Chen,S., Tsai,C. and Hsiue,G. (2012) Bioengineered periosteal progenitor cell sheets to enhance tendon-bone healing in a bone tunnel. Biomedical Journal, 35, 473 - 480.

Bone Marrow-Derived Mesenchymal Stem Cell (BMSC)

Chen,K., Sahoo,S., He,P., Ng,K.S., Toh,S.L. and Goh,J.C.H. (2012) A Hybrid Silk/RADA-Based Fibrous Scaffold with Triple Hierarchy for Ligament Regeneration. Tissue Engineering Part A. 18, 1399 - 1409.

Rabbit Bone Marrow Stromal Cells and Osteoblasts Co-Culture

Chen,K., Teh,T.K.H., Ravi,S., Toh,S.L. and Goh,J.C.H. (2012) Osteochondral Interface Generation by Rabbit Bone Marrow Stromal Cells and Osteoblasts Co-culture. Tissue Engineering 18, 1902 - 1911.

Human Periodontal Ligaments

Chen,Y.J., Jeng,J.H., Chang,H.H., Huang,M.Y., Tsai,F.F. and Jane Yao,C.C. (2012) Differential regulation of

collagen, lysyl oxidase and MMP2 in human periodontal ligament cells by lowand highlevel mechanical stretching. Journal of Periodontal Research, doi: 10.1111/jre.12028.

Dog Articular Cartilage

Cheong-Ho,C. (2012) Cartilage Regeneration Using a Fibrin and Autologous Cultured Chondrocytes Mixture in a Canine Model. Journal of Tissue Science & Engineering 3, 114.

Human Dermal Fibroblasts

Chiang,H.M., Chen,H.C., Lin,T.J., Shih,I. and Wen,K.C. (2012) Michelia alba extract attenuates UVB-induced expression of matrix metalloproteinases via MAP kinase pathway in human dermal fibroblasts. Food and Chemical Toxicology 50, 4260 – 4269.

Human Nasal Polyp-Derived Fibroblasts

Cho,J.S., Moon,Y.M., Park,I.H., Um,J.Y., Moon,J.H., Park,S.J., Lee,S.H., Kang,H.J. and Lee,H.M. (2012) Epigenetic

regulation of myofibroblast differentiation and extracellular matrix production in nasal polypderived fibroblasts. Clinical & Experimental Allergy, 42, 872 - 882.

Osteoblastic MC3T3-E1 Cells

Choi,E.M. (2012) Sunflower seed extract enhances the differentiation of osteoblastic MC3T3-E1 cells. Food and Agricultural Immunology doi: 10.1080/09540105.2012.716399.

Human Placenta-Derived Extracellular Matrix

Choi,J.S., Kim,J.D., Yoon,H.S. and Cho,Y.W. (2012) Full-Thickness Skin Wound Healing Using Human Placenta-Derived Extracellular Matrix Containing Bioactive Molecules. Tissue Engineering Part A. 19, 329 – 339.

Porcine Adipose Tissue

Choi,Y.C., Choi,J.S., Kim,B.S., Kim,J.D., Yoon,H.I. and Cho,Y.W. (2012) Decellularized Extracellular Matrix Derived from Porcine Adipose Tissue as a Xenogeneic Biomaterial for Tissue Engineering. Tissue Engineering Part C: Methods, 18, 866 - 876.

Primary Human Osteoblasts

Chopra,K., Mummery,P.M., Derby,B. and Gough,J.E. (2012) Gel-cast glass-ceramic tissue scaffolds of controlled architecture produced via stereolithography of moulds. Biofabrication, 4, 045002.

Rat Lung Fibroblasts

Chou,H.C., Lang,Y.D., Wang,L.F., Wu,T.Y., Hsieh,Y.F. and Chen,C.M. (2012) Angiotensin II Type 1 Receptor Antagonist Attenuates Lung Fibrosis in Hyperoxia-Exposed Newborn Rats. Journal of Pharmacology and Experimental Therapeutics 340, 169-175.

Human and Murine Skin

Dees,C., Tomcik,M., PalumboZerr,K., Akhmetshina,A., Beyer,C., Lang,V., Horn,A., Zerr,P., Zwerina,J. and

Gelse,K. (2012) JAK2 as a novel mediator of the profibrotic effects of TGFβ in systemic sclerosis. Arthritis & Rheumatism, 64, 3006 - 3015.

Kidney Tissue

Djudjaj,S., Chatziantoniou,C., Raffetseder,U., Guerrot,D., Dussaule,J.C., Boor,P., Kerroch,M., Hanssen,L.,

Brandt,S. and Dittrich,A. (2012) Notch3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury. The Journal of Pathology 228, 286 – 299.

Human Colonic Epithelial Cell lines and Primary Human Colonic Subepithelial Myofibroblasts

Drygiannakis,I., Valatas,V., Sfakianaki,O., Bourikas,L., Manousou,P., Kambas,K., Ritis,K., Kolios,G. and Kouroumalis,E. (2012) Proinflammatory cytokines induce crosstalk between colonic epithelial cells and subepithelial myofibroblasts: Implication in intestinal fibrosis. Journal of Crohn's and Colitis, http://dx.doi.org/10.1016/j.crohns.2012.04.008.

Human Cardiac Tissue

de Jong,S., van Veen,T.A.B., de Bakker,J.M.T. and van Rijen,H.V.M. (2012) Monitoring cardiac fibrosis: a technical challenge. Netherlands Heart Journal 20, 44 – 48.

Wharton’s Jelly-Derived Mesenchymal Stromal Cells

Du,T., Cheng,J., Zhong,L., Zhao,X.F., Zhu,J., Zhu,Y.J. and Liu,G.H. (2012) The alleviation of acute and chronic kidney injury by human Wharton's jelly-derived mesenchymal stromal cells triggered by ischemia-reperfusion injury via an endocrine mechanism. Cytotherapy, 14, 1215 - 1227.

A549 Cells and Human Bronchial Cells, Lung Tissue

Dunmore,R., Carruthers,A.M., Bell,M.J., Zhang,H., Hogaboam,C.M., Peng,X., Herzog,E.L., Knight,D.A., Martinez,F.J. and Sleeman,M.A. (2012) An Assessment of Epithelial and Mesenchymal Phenotypes in Experimental and Clinical Pulmonary Fibrosis doi: 10.5402/2012/153971.

Articular Cartilage Constructs

Eleswarapu,S.V. and Athanasiou,K.A. (2012) TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs. Acta Biomaterialia, http://dx.doi.org/10.1016/j.actbio.2012.10.031.

Human Tendon Fibroblasts

Erisken,C., Zhang,X., Moffat,K.L., Levine,W.N. and Lu,H.H. (2012) Scaffold Fiber Diameter Regulates Human Tendon Fibroblast Growth and Differentiation. Tissue Engineering Part A, 19, 519 – 528.

Murine Liver Tissue

Fairfax,K.C., Amiel,E., King,I.L., Freitas,T.C., Mohrs,M. and Pearce,E.J. (2012) IL-10R Blockade during Chronic Schistosomiasis Mansoni Results in the Loss of B Cells from the Liver and the Development of Severe Pulmonary Disease. PLoS Pathogens, 8, e1002490.

Bone

Ferreira,A.M., Gentile,P., Sartori,S., Pagliano,C., Cabrele,C., Chiono,V. and Ciardelli,G. (2012) Biomimetic soluble collagen purified from bones. Biotechnology Journal 7, 1386 – 1394.

Murine and Human Fibrocytes

Field,J.J., Burdick,M.D., DeBaun,M.R., Strieter,B.A., Liu,L., Mehrad,B., Rose,C.E., Linden,J. and Strieter,R.M. (2012) The Role of Fibrocytes in Sickle Cell Lung Disease. PloS one, 7, e33702.

Murine Lung Tissue

Fujino,N., Kubo,H., Suzuki,T., He,M., Suzuki,T., Yamada,M., Takahashi,T., Ota,C. and Yamaya,M. (2012) Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice. Experimental Lung Research 38, 28 – 36.

Murine Bladder Tissue

Fu,C.L., Odegaard,J.I., De'Broski,R.H. and Hsieh,M.H. (2012) A Novel Mouse Model of Schistosoma haematobium Egg-Induced Immunopathology. PLoS Pathogens, 8, e1002605.

Murine Lung Tissue

Fujino,N., Kubo,H., Suzuki,T., He,M., Suzuki,T., Yamada,M., Takahashi,T., Ota,C. and Yamaya,M. (2012) Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice. Experimental Lung Research, 38, 28 – 36.

Rat Lung

Gao,F., Fish,B.L., Szabo,A., Doctrow,S.R., KMA,L., Molthen,R.C., Moulder,J.E., Jacobs,E.R. and Mdehora,M. (2012) Short-Term Treatment with a SOD/Catalase Mimetic, EUK-207, Mitigates Pneumonitis and Fibrosis after Single-Dose Total-Body or Whole-Thoracic Irradiation. Radiation Research, 178, 468-480.

Murine Lung

Giannandrea,M., Yee,M., O'Reilly,M.A. and Lawrence,B.P. (2012) Memory CD8+ T cells are sufficient to alleviate impaired host resistance to influenza A virus infection caused by neonatal oxygen supplementation. Clinical and Vaccine Immunology, 19, 1432-1441.

Rat Bone Marrow Mesenchymal Stem Cells

Gomide,V.S., Zonari,A., Ocarino,N.M., Goes,A.M., Serakides,R. and Pereira,M.M. (2012) In vitro and in vivo

osteogenic potential of bioactive glassPVA hybrid scaffolds colonized by mesenchymal stem cells. Biomedical Materials, 7, 015004.

Murine Lung Tissue

Gorshkova,I., Zhou,T., Mathew,B., Jacobson,J.R., Takekoshi,D., Bhattacharya,P., Smith,B., Aydogan,B., Weichselbaum,R.R. and Natarajan,V. (2012) Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. Journal of Lipid Research, doi: 10.1194/jlr.M026039.

Lamb Trachea and Amniotic Mesenchymal Stem Cells

Gray,F.L., Turner,C.G., Ahmed,A., Calvert,C.E., Zurakowski,D. and Fauza,D.O. (2012) Prenatal tracheal

reconstruction with a hybrid amniotic mesenchymal stem cellsengineered construct derived from decellularized airway. Journal of Pediatric Surgery, 47, 1072-1079.

Murine Abdominal Wall Wound

Hoffman,A., Baxter,R., Nasar,A., Gardner,T.R., Kumara,S., Cordon-Cardo,C., Ahmed,A., Newman,R.A., Zmora,O. and Whelan,R.L. (2012) Perioperative Polyphenon E, a Green Tea Extract, Does Not Affect the Wound Complication Rate in Mice After Sham Laparotomy yet Has an Inhibitory Effect on Wound Healing. Surgical Innovation, 19, 399 - 406.

Nasal Polyp-Derived Fibroblasts

Hong,S.M., Lee,H.M., Chung,S.W., Park,H., Cho,J.S., Um,J.Y. and Lee,H.R. (2012) Effect of Caffeic Acid on Nasal Polyp Derived Fibroblasts. Otolaryngology--Head and Neck Surgery, 147, 245.

Murine Fibroblasts and Skin

Horn,A., Palumbo,K., Cordazzo,C., Dees,C., Akhmetshina,A., Tomcik,M., Zerr,P., Avouac,J., Gusinde,J. and Zwerina,J. (2012) Hedgehog signaling controls fibroblast activation and tissue fibrosis in systemic sclerosis. Arthritis & Rheumatism, 64, 2724 - 2733.

Human Embryonic Skin Fibroblasts

Hsiao,C.Y., Hung,C.Y., Tsai,T.H. and Chak,K.F. (2012) A Study of the Wound Healing Mechanism of a Traditional Chinese Medicine, Angelica sinensis, Using a Proteomic Approach. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012.467531.

Fibroblasts and Rat Wound

Hsiao,C.Y., Tsai,T.H. and Chak,K.F. (2012) The Molecular Basis of Wound Healing Processes Induced by Lithospermi Radix: A Proteomics and Biochemical Analysis. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012/508972

Human and Murine Skin

Hu,B., Castillo,E., Harewood,L., Ostano,P., Reymond,A., Dummer,R., Raffoul,W., Hoetzenecker,W., Hofbauer,G.F.L. and Dotto,G.P. (2012) Multifocal Epithelial Tumors and Field Cancerization from Loss of Mesenchymal CSL Signaling. Cell, 149, 1207-1220.

Heart Valves

Huang,H.Y.S., Balhouse,B.N. and Huang,S. (2012) Application of Simple Biomechanical and Biochemical Tests to Heart Valve Leaflets: Implications for Heart Valve Characterization and Tissue Engineering. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine doi: 10.1177/0954411912455004.

Human Cartilage Explants Culture and Chondrocytes

Huh,J.E., Seo,B.K., Baek,Y.H., Lee,S., Lee,J.D., Choi,D.Y. and Park,D.S. (2012) Standardized butanol fraction of WIN-34B suppresses cartilage destruction via inhibited production of matrix metalloproteinase and inflammatory mediator in osteoarthritis human cartilage explants culture and chondrocytes. BMC Complementary and Alternative Medicine, 12, 256.

Human Fibroblasts

Iyer,P., Walker,K.J. and Madihally,S.V. (2012) Increased matrix synthesis by fibroblasts with decreased proliferation on synthetic chitosan-gelatin porous structures. Biotechnology and Bioengineering 109, 1314 – 1325.

Porcine Wounds

Jackson,J.E., Kopecki,Z., Adams,D.H. and Cowin,A.J. (2012) Flii neutralizing antibodies improve wound healing in porcine preclinical studies. Wound Repair and Regeneration, 20, 523 – 536.

Chondrogenic-Induced Bone Mesenchymal Stem Cells

Jia,S., Liu,L., Pan,W., Meng,G., Duan,C., Zhang,L., Xiong,Z. and Liu,J. (2012) Oriented cartilage extracellular matrix-derived scaffold for cartilage tissue engineering. Journal of Bioscience and Bioengineering, 113, 647 - 653.

Chondrogenic-Induced Bone Mesenchymal Stem Cells

Jia,S., Liu,L., Pan,W., Meng,G., Duan,C., Zhang,L., Xiong,Z. and Liu,J. (2012) Oriented cartilage extracellular matrix-derived scaffold for cartilage tissue engineering. Journal of Bioscience and Bioengineering, http://dx.doi.org/10.1016/j.jbiosc.2011.12.009.

Human Patellar Tendon Fibroblasts

Jiang,C., Shao,L., Wang,Q. and Dong,Y. (2012) Repetitive mechanical stretching modulates transforming growth factor-β induced collagen synthesis and apoptosis in human patellar tendon fibroblasts. Biochemistry and Cell Biology, 90, 667-674.

Rat Lung

Jiang,J.S., Lang,Y.D., Chou,H.C., Shih,C.M., Wu,M.Y., Chen,C.M. and Wang,L.F. (2012) Activation of the Renin-Angiotensin System in Hyperoxia-Induced Lung Fibrosis in Neonatal Rats. Neonatology, 101, 47-54.

Human Rotator Cuff Tendon Tenocytes

Jo,C.H., Kim,J.E., Yoon,K.S. and Shin,S. (2012) Platelet-Rich Plasma Stimulates Cell Proliferation and Enhances Matrix Gene Expression and Synthesis in Tenocytes From Human Rotator Cuff Tendons With Degenerative Tears. The American Journal of Sports Medicine, 40, 1035-1045.

Rat Bone Marrow Stromal Cells

Joiner,D.M., Tayim,R.J., Kadado,A. and Goldstein,S.A. Bone marrow stromal cells from aged male rats have delayed mineralization and reduced response to mechanical stimulation through nitric oxide and ERK1/2 signaling during osteogenic differentiation. Biogerontology, 13, 467 - 478.

Murine Lung Tissue

Jonasson,S., Koch,B. and Bucht,A. (2012) Inhalation of chlorine causes long-standing lung inflammation and airway hyperresponsiveness in a murine model of chemical-induced lung injury. Toxicology 303, 34 – 42.

Murine Lung Tissue

Jones,C.P., Gregory,L.G., Causton,B., Campbell,G.A. and Lloyd,C.M. (2012) Activin A and TGF-β promote TH9

cellmediated pulmonary allergic pathology. Journal of Allergy and Clinical Immunology, 129, 1000 – 1010.e3.

Murine Lung and Skin

Jun,J.B., Kim,J.K., Na,Y.I., Han,H., Paik,S.S., Kim,S.H. and Kim,Y.H. (2012) Dietary Flavonoid Apigenin is not Effective in Preventing Development of a Bleomycin-Induced Murine Model of Scleroderma. Journal of Rheumatic Diseases, 19, 206-211.

Decellularised Sheep Liver

Kajbafzadeh,A.M., Javan-Farazmand,N., Monajemzadeh,M. and Baghayee,A. (2012) Determining the Optimal Decellularization and Sterilization Protocol for Preparing a Tissue Scaffold of a Human-sized Liver Tissue. Tissue Engineering, doi: 10.1089/ten.TEC.2012.0334.

Murine Lung

Kang,M.J., Choi,J.M., Kim,B.H., Lee,C.M., Cho,W.K., Choe,G., Kim,D.H., Lee,C.G. and Elias,J.A. (2012) IL-18 Induces Emphysema, and Airway and Vascular Remodeling via IFN-γ, IL-17A and IL-13. American Journal of Respiratory and Critical Care Medicine, 185, 1205 - 1217.

Human Prostate Cancer Cell Line PC-3

Kapinas,K., Lowther,K.M., Kessler,C.B., Tilbury,K., Lieberman,J.R., Tirnauer,J.S., Campagnola,P. and Delany,A.M. (2012) Bone matrix osteonectin limits prostate cancer cell growth and survival. Matrix Biology 31, 299 – 307.

Bronchoalveolar Lavage Fluid

Karmouty-Quintana,H., Zhong,H., Acero,L., Weng,T., Melicoff,E., West,J.D., Hemnes,A., Grenz,A., Eltzschig,H.K. and Blackwell,T.S. (2012) The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. The FASEB Journal, 26, 2546-2557.

Murine Lung

Kass,D.J., Yu,G., Loh,K.S., Savir,A., Borczuk,A., Kahloon,R., Juan Guardela,B., Deiuliis,G., Tedrow,J. and Choi,J. (2012) Cytokine-Like Factor 1 Gene Expression Is Enriched in Idiopathic Pulmonary Fibrosis and Drives the Accumulation of CD4+ T Cells in Murine Lungs: Evidence for an Antifibrotic Role in Bleomycin Injury. The American journal of pathology, 180, 1963 – 1978.

Lung And Cardiovascular Tissue

Katwa,P., Wang,X., Urankar,R.N., Podila,R., Hilderbrand,S.C., Fick,R.B., Rao,A.M., Ke,P.C., Wingard,C.J. and

Brown,J.M. (2012) A Carbon Nanotube Toxicity Paradigm Driven by Mast Cells and the IL33/ST2 Axis. Small 8, 2904 – 2912.

Murine Skin

Kavian,N., Marut,W., Servettaz,A., Laude,H., Nicco,C., Ch+®reau,C., Weill,B. and Batteux,F. (2012) Arsenic Trioxide Prevents Murine Sclerodermatous Graft-versus-Host Disease. The Journal of Immunology, 188, 5142-5149.

Murine Skin and Lung

Kavian,N., Marut,W., Servettaz,A., Nicco,C., Chéreau,C., Lemaréchal,H., Borderie,D., Dupin,N., Weill,B. and

Batteux,F. (2012) ROSmediated killing of activated fibroblasts by arsenic trioxide ameliorates fibrosis in a murine model of SSc. Arthritis & Rheumatism 64, 3430 - 3440.

Murine Skin and Lung Tissue

Kavian,N., Servettaz,A., Marut,W., Nicco,C., Chéreau,C., Weill,B. and Batteux,F. (2012) Sunitinib inhibits the

phosphorylation of plateletderived growth factor receptor β in the skin of mice with sclerodermalike features and prevents the development of the disease. Arthritis & Rheumatism, 64, 1990-2000.

Human Marrow Derived Stromal Cells

Khan,M.R., Donos,N., Salih,V. and Brett,P.M. (2012) The enhanced modulation of key bone matrix components by modified Titanium implant surfaces. Bone 50, 1 – 8.

Human Adipose Tissue

Kim,B.S., Choi,J.S., Kim,J.D., Yoon,H.I., Choi,Y.C. and Cho,Y.W. (2012) Human collagen isolated from adipose tissue. Biotechnology Progress 28, 973 - 980.

Murine Lung

Kinjo,T., Tomaru,K., Haines,D.C. and Klinman,D.M. (2012) The counter regulatory response induced by CpG oligonucleotides prevents bleomycin induced pneumopathy. Respiratory Research, 13, 47.

Rat Lung

Kma,L., Gao,F., Fish,B.L., Moulder,J.E., Jacobs,E.R. and Medhora,M. (2012) Angiotensin Converting Enzyme Inhibitors Mitigate Collagen Synthesis Induced by a Single Dose of Radiation to the Whole Thorax. Journal of Radiation Research, 53, 10-17.

Human Hepatic Stellate Cells

Knight,V., Tchongue,J., Lourensz,D., Tipping,P. and Sievert,W. (2012) Proteaseactivated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells. Hepatology 55, 879 – 887.

Porcine Skin

Kono,A., Oguri,A., Yokoo,K. and Watanabe,H. (2012) YAG laser treatment causes rapid degeneration and regeneration of collagen fibres in pig skin and facilitates fibroblast growth. Journal of Plastic Surgery and Hand Surgery, 46, 308-312.

Rat Hepatic Stellate Cells and LX-2, a Human HSC Cell Line

Kuo,J.J., Wang,C.Y., Lee,T.F., Huang,Y.T. and Lin,Y.L. (2012) Paeoniae Radix Reduces PDGF-Stimulated Hepatic Stellate Cell Migration. Planta medica, 78, 341 – 348.

Human Lung Tissue

Lagares,D., Busnadiego,O., GarcíaFernández,R.A., Kapoor,M., Liu,S., Carter,D.E., Abraham,D., ShiWen,X., Carreira,P. and Fontaine,B.A. (2012) Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation. Arthritis & Rheumatism, 64, 1653-1664.

Murine Lung

Lee,C.G., Herzog,E.L., Ahangari,F., Zhou,Y., Gulati,M., Lee,C.M., Peng,X., Feghali-Bostwick,C., Jimenez,S.A. and Varga,J. (2012) Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling. The Journal of Immunology, 189, 2635-2644.

Nasal Polyp-Derived Fibroblasts

Lee,H. and Park,I.H. (2012) 239 Berberine Inhibits Myofibroblast Differentiation in Nasal Polyp-derived Fibroblast via P-38 Pathway. World Allergy Organization Journal, 5, S78.

Rat Heart Tissue

Lee,J.E., Yi,C., Jeon,B.T., Shin,H.J., Kim,S.K., Jung,T.S., Choi,J.Y. and Roh,G.S. (2012) Alpha-lipoic acid attenuates cardiac fibrosis in Otsuka Long-Evans Tokushima Fatty rats. Cardiovascular Diabetology, 11, 111.

Bone Marrow Mesenchymal Stem Cells

Lin,B.N., Whu,S.W., Chen,C.H., Hsu,F.Y., Chen,J.C., Liu,H.W., Chen,C.H. and Liou,H.M. (2012) Bone marrow

mesenchymal stem cells, plateletrich plasma and nanohydroxyapatitetype I collagen beads were integral parts of biomimetic bone substitutes for bone regeneration. Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.1472.

Murine Lung

Li,L.F., Chu,P.H., Hung,C.Y., Kao,W.Y., Lin,M.C., Liu,Y.Y. and Yang,C.T. (2012) Lumican Regulates Ventilation-Induced Epithelial-Mesenchymal Transition through Extracelluar Signal-Regulated Kinase Pathway. CHEST Journal, doi: 10.1378/chest.12-3058.

Murine Heart and Cardiac Fibroblasts

Liang,H., Zhang,C., Ban,T., Liu,Y., Mei,L., Piao,X., Zhao,D., Lu,Y., Chu,W. and Yang,B. (2012) A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis. The International Journal of Biochemistry & Cell Biology 44, 2152 – 2160.

Rabbit Cranial Cruciate Ligaments

Light,V.A., Montgomery,R.D. and Akingbemi,B.T. (2012) Sex hormone regulation of collagen concentrations in cranial cruciate ligaments of sexually immature male rabbits. American Journal of Veterinary Research, 73, 1186-1193.

Fibroblast Cells (L929)

Lin,H.Y., Chen,H.H., Chang,S.H. and Ni,T.S. (2012) Pectin-chitosan-PVA nanofibrous scaffold made by electrospinning and its potential use as a skin tissue scaffold, doi: 10.1080/09205063.2012.693047.

Murine Lung

Lin,L.J., Lin,C.C., Wang,S.D., Chao,Y.P. and Kao,S.T. (2012) The Immunomodulatory Effect of You-Gui-Wan on Dermatogoides-pteronyssinus-Induced Asthma. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012/476060.

Human Gingival Fibroblasts

Lin,S.J., Lu,H.K., Lee,H.W., Chen,Y.C., Li,C.L. and Wang,L.F. (2012) Nitric oxide inhibits androgen

receptormediated collagen production in human gingival fibroblasts. Journal of Periodontal Research, doi: 47, 701 - 710.

Murine Adult Fibroblasts/Smooth Muscle

Liu,S. and Leask,A. (2012) Integrin β1 is required for maintenance of vascular tone in postnatal mice. Journal of cell communication and signaling, 6, 175 - 180.

Murine Lung Tissue

MacKinnon,A.C., Gibbons,M.A., Farnworth,S.L., Leffler,H., Nilsson,U.J., Delaine,T., Simpson,A.J., Forbes,S.J., Hirani,N. and Gauldie,J. (2012) Regulation of TGF-β1 Driven Lung Fibrosis by Galectin-3. American Journal of Respiratory and Critical Care Medicine, 185, 537-546.

Murine Intestine

Månsson,L.E., Montero,M., Zarepour,M., Bergstrom,K.S., Ma,C., Huang,T., Man,C., Grassl,G.A. and Vallance,B.A. (2012) MyD88 signaling promotes both mucosal homeostatic and fibrotic responses during Salmonella-induced colitis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 303, G311-G323.

Meniscus Cell/Articular Chondrocyte Co-Culture

MacBarb,R.F., Makris,E.A., Hu,J.C. and Athanasiou,K.A. (2012) A chondroitinase-ABC and TGF-β1 treatment regimen for enhancing the mechanical properties of tissue engineered fibrocartilage. Acta Biomaterialia 9, 4626 – 4634.

Rat Lung

Mahmood,J., Jelveh,S., Zaidi,A., Doctrow,S.R. and Hill,R.P. (2012) Mitigation of Radiation-Induced Lung Injury with EUK-207 and Genistein: Effects in Adolescent Rats. Radiation Research, http://dx.doi.org/10.1667/RR2954.1.

Murine Skin and Lungs

Marut,W.K., Kavian,N., Servettaz,A., Nicco,C., Ba,L.A., Doering,M., Chéreau,C., Jacob,C., Weill,B. and Batteux,F. (2012) The Organotelluride Catalyst (PHTE)2NQ Prevents HOCl-Induced Systemic Sclerosis in Mouse. Journal of Investigative Dermatology, 132, 1125 – 1132.

Brain and Spinal Cord ECM Scaffolds

Medberry,C.J., Crapo,P.M., Siu,B.F., Carruthers,C.A., Wolf,M.T., Nagarkar,S.P., Agrawal,V., Jones,K.E., Kelly,J. and Johnson,S.A. (2012) Hydrogels derived from central nervous system extracellular matrix. Biomaterials 34, 1033 – 1040.

Human Lung Fibroblasts

Mendoza,C., Jiménez,A.V., Rangel,C., Lozano,A., Morales,V., Becerril,C., Chavira,R., Ruiz,V., Barrera,L. and Montaño,M. (2012) DHEA has strong antifibrotic effects and is decreased in idiopathic pulmonary fibrosis. European Respiratory Journal, doi: 10.1183/0903/936.00027412.

Human Adipose Tissue-Derived MSCs

Merceron,C., Portron,S., VignesColombeix,C., Rederstorff,E., Masson,M., Lesoeur,J., Sourice,S., Sinquin,C.,

ColliecJouault,S. and Weiss,P. (2012) Pharmacological Modulation of Human Mesenchymal Stem Cell Chondrogenesis by a Chemically Oversulfated Polysaccharide of Marine Origin: Potential Application to Cartilage Regenerative Medicine. Stem Cells, 30, 471-480.

Human Lung Tissue

Milara,J., Navarro,R., Juan,G., Peiró,T., Serrano,A., Ramón,M., Morcillo,E. and Cortijo,J. (2012) Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition. Thorax, 67, 147-156.

Human Tenocytes

Millar,N.L., Reilly,J.H., Kerr,S.C., Campbell,A.L., Little,K.J., Leach,W.J., Rooney,B.P., Murrell,G.A.C. and McInnes,I.B. (2012) Hypoxia: a critical regulator of early human tendinopathy. Annals of the Rheumatic Diseases, 71, 302-310.

Human Lung Fibroblast Cells

Mishra,A., Rojanasakul,Y., Chen,B.T., Castranova,V., Mercer,R.R. and Wang,L. (2012) Assessment of Pulmonary Fibrogenic Potential of Multiwalled Carbon Nanotubes in Human Lung Cells. Journal of Nanomaterials, doi: 10.1155/2012/930931.

Human Retinoblastoma (RB) Cell Line Y79

Mitra,M., Mohanty,C., Harilal,A., Maheswari,U.K., Sahoo,S.K. and Krishnakumar,S. (2012) A novel in vitro three-dimensional retinoblastoma model for evaluating chemotherapeutic drugs. Molecular Vision, 18, 1361.

Rat Lung Tissue

Miyake,K., Tani,K., Kakiuchi,S., Suzuka,C., Toyoda,Y., Kishi,J., Tezuka,T., Yuasa,S., Hanibuchi,M. and Aono,Y. (2012) Epidermal growth factor receptor-tyrosine kinase inhibitor (gefitinib) augments pneumonitis, but attenuates lung fibrosis in response to radiation injury in rats. The Journal of Medical Investigation, 59, 175.

Murine Lung

Miyoshi,K., Yanagi,S., Kawahara,K., Nishio,M., Tsubouchi,H., Imazu,Y., Koshida,R., Matsumoto,N., Taguchi,A. and Yamashita,S. (2012) Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity. American journal of respiratory and critical care medicine, doi: 10.1164/rccm.201205-08510c.

Rat Dermal Wound

Mohanty,C., Das,M. and Sahoo,S.K. (2012) Sustained Wound Healing Activity of Curcumin Loaded Oleic Acid Based Polymeric Bandage in a Rat Model. Molecular Pharmaceutics 9, 2801 – 2811.

Human Skin Biopsies

Moinzadeh,P., Denton,C.P., Abraham,D., Ong,V., Hunzelmann,N., Eckes,B. and Krieg,T. (2012) Biomarkers for skin involvement and fibrotic activity in scleroderma. Journal of the European Academy of Dermatology and Venereology 26, 267 – 276.

Normal Human Lung Fibroblasts

Montes,E., Ruiz,V., Checa,M., Maldonado,V., Melendez-Zajgla,J., Montaño,M., Ordoñez-Razo,R., Cisneros,J., García-de-Alba,C. and Pardo,A. (2012) Renin is an angiotensin-independent profibrotic mediator: role in pulmonary fibrosis. European Respiratory Journal, 39, 141-148.

Normal Human Lung Fibroblasts

Montes,E., Ruiz,V., Checa,M., Maldonado,V., Zajgla,J.M., Montaño,M., Razo,R.O., Cisneros,J., García-de-Alba,C. and Pardo,A. (2012) Renin is an angiotensin-independent profibrotic mediator. Role in pulmonary fibrosis. European Respiratory Journal, 39, 141-148.

Scaffold Seeded with Rat Bone Marrow Stromal Cells

Muhammad,K.B., Abas,W.A.B.W., Kim,K.H., Pingguan-Murphy,B., Zain,N.M. and Akram,H. (2012) In vitro comparative study of white and dark polycaprolactone trifumarate in situ cross-linkable scaffolds seeded with rat bone marrow stromal cells. Clinics, 67, 629.

Bovine Chondrocytes

Mujeeb,A., Miller,A.F., Saiani,A. and Gough,J.E. (2012) Self-assembled octapeptide scaffolds for in vitro chondrocyte culture. Acta Biomaterialia 9, 4609 – 4617.

Murine Lung

Murray,A.R., Kisin,E.R., Tkach,A.V., Yanamala,N., Mercer,R., Young,S.H., Fadeel,B., Kagan,V.E. and Shvedova,A.A. (2012) Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos. Particle and Fibre Toxicology, 9, 10.

Alveolar Septa

Ohta,H., Chiba,S., Ebina,M., Furuse,M. and Nukiwa,T. (2012) Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis. American Journal of Physiology-Lung Cellular and Molecular Physiology, 302, L193-L205.

A Skin Fibroblast Cell Line

Okamoto,Y., Hasegawa,M., Matsushita,T., Hamaguchi,Y., Huu,D.L., Iwakura,Y., Fujimoto,M. and Takehara,K. (2012) Potential roles of interleukin 17A in the development of skin fibrosis. Arthritis & Rheumatism 64, 3726 – 3735.

Primary Rat Osteoblasts

Orriss,I.R., Key,M.L., Brandao-Burch,A., Patel,J.J., Burnstock,G. and Arnett,T.R. (2012) The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors. Bone, 51, 389 – 400.

Human Skin Fibroblasts

Oyoshi,M.K., He,R., Kanaoka,Y., ElKhal,A., Kawamoto,S., Lewis,C.N., Austen,K.F. and Geha,R.S. (2012) Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. Proceedings of the National Academy of Sciences, 109, 4992-4997.

Murine Colon

Oz,H.S., Zhong,J. and de Villiers,W.J.S. (2012) Osteopontin ablation attenuates progression of colitis in TNBS model. Digestive diseases and sciences, 57, 1554 - 1561.

Human Renal Mesangial Cells

Paccosi,S., Musilli,C., Mangano,G., Guglielmotti,A. and Parenti,A. (2012) The monocyte chemotactic protein synthesis inhibitor bindarit prevents mesangial cell proliferation and extracellular matrix remodeling. Pharmacological Research 66, 526 – 535.

Cardiomyocytes

Panse,K.D., Felkin,L.E., López-Olañeta,M.M., Gómez-Salinero,J., Villalba,M., Muñoz,L., Nakamura,K., Shimano,M., Walsh,K. and Barton,P.J.R. (2012) Follistatin-Like 3 Mediates Paracrine Fibroblast Activation by Cardiomyocytes. Journal of Cardiovascular Translational Research, 5, 814 – 826.

Murine Lung and Lung Fibroblasts

Park,C.S., Bang,B.R., Kwon,H.S., Moon,K.A., Kim,T.B., Lee,K.Y., Moon,H.B. and Cho,Y.S. (2012) Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase. Biochemical Pharmacology 84, 1660 – 1670.

Nasal Polyp-Derived Fibroblasts

Park,I.H. and Lee,H. (2012) 153 Effect of Simvastatin on Transforming Growth Factor BETA-1-Induced Myofibroblast Differentiation and Collagen Production in Nasal Polyp-Derived Fibroblasts. World Allergy Organization Journal, 5, S51.

Nasal Polyp-Derived Fibroblasts

Park,I.H., Park,S.J., Cho,J.S., Moon,Y.M., Moon,J.H., Kim,T.H., Lee,S.H. and Lee,H.M. (2012) Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. American Journal of Rhinology & Allergy, 26, 7-11.

Nasal Polyp-Derived Fibroblasts

Park,I.H., Park,S.J., Cho,J.S., Moon,Y.M., Kim,T.H., Lee,S.H. and Lee,H.M. (2012) Role of Reactive Oxygen Species in Transforming Growth Factor Beta1-Induced Alpha Smooth-Muscle Actin and Collagen Production in Nasal Polyp-Derived Fibroblasts. International Archives of Allergy and Immunology, 159, 278 – 286.

Porcine Liver

Park,K.M., Park,S.M., Yang,S.R., Hong,S.H. and Woo,H.M. (2012) Preparation of immunogen-reduced and biocompatible extracellular matrices from porcine liver. Journal of Bioscience and Bioengineering 115, 207 – 215.

Nasal Polyp-Derived Fibroblasts

Park,S.A., Park,I.H., Cho,J.S., Moon,Y.M., Lee,S.H., Kim,T.H., Lee,S.H. and Lee,H.M. (2012) Effect of [6]-gingerol on myofibroblast differentiation in transforming growth factor beta 1-induced nasal polyp-derived fibroblasts. American Journal of Rhinology & Allergy, 26, 97-103.

Murine Lung

Park,S.J., Lee,K.S., Lee,S.J., Kim,S.R., Park,S.Y., Jeon,M.S., Lee,H.B. and Lee,Y.C. (2012) l-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κ(NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF). International Journal of Molecular Sciences, 13, 7915-7937.

Rat Cervical Tissue

Poellmann,M.J., Chien,E.K., McFarlin,B.L. and Johnson,A.J.W. (2012) Mechanical and structural changes of the rat cervix in late-stage pregnancy. Journal of the Mechanical Behavior of Biomedical Materials 17, 66 – 75.

Murine MLO-A5 Pre-Osteocyte Cell Line

Prideaux,M., Loveridge,N., Pitsillides,A.A. and Farquharson,C. (2012) Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation. PloS one, 7, e36786.

Murine Lung

Qin,X.J., Zhang,G.S., Zhang,X., Qiu,Z.W., Wang,P.L., Li,Y.W., Li,W., Xie,Q.M., Ke,Y.H. and Lee,J.J. (2012) Protein

tyrosine phosphatase SHP2 regulates TGFβ1 production in airway epithelia and asthmatic airway remodeling in mice. Allergy 67, 1547 – 1556.

Human Mesenchymal Stem Cells

Re-em,T., Witte,F., Willbold,E., Ruvinov,E. and Cohen,S. (2012) Simultaneous regeneration of articular cartilage and subchondral bone induced by spatially-presented TGF-beta and BMP-4 in a bi-layer affinity binding system. Acta Biomaterialia, 8, 3283 - 3293.

Murine Systemic Sclerosis Fibroblasts

Reich,N., Tomcik,M., Zerr,P., Lang,V., Dees,C., Avouac,J., Palumbo,K., Horn,A., Akhmetshina,A. and Beyer,C. (2012) Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis. Annals of the Rheumatic Diseases, 71, 737 - 745.

Rat Liver

Ricci,E., Vanosi,G., Lindenmair,A., Hennerbichler,S., Peterbauer-Scherb,A., Wolbank,S., Cargnoni,A., Signoroni,P.B., Campagnol,M. and Gabriel,C. (2012) Anti-fibrotic effects of fresh and cryopreserved human amniotic membrane in a rat liver fibrosis model. Cell and Tissue Banking, doi: 10.1007/s10561-012-9337-x.

Rat Aorta

Roan,J.N., Tsai,Y.C., Chen,I.W., Chang,S.W., Huang,C.C. and Lam,C.F. (2012) Inhibition of cyclooxygenase-2 modulates phenotypic switching of vascular smooth muscle cells during increased aortic blood flow. Heart and vessels, 27, 307 - 315.

Murine Lung Tissue

Rey-Parra,G.J., Vadivel,A., Coltan,L., Hall,A., Eaton,F., Schuster,M., Loibner,H., Penninger,J.M., Kassiri,Z. and Oudit,G.Y. (2012) Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury. Journal of Molecular Medicine, 90, 637 – 647.

Rat Lung Tissue

Roberts,J.R., Mercer,R.R., Chapman,R.S., Cohen,G.M., Bangsaruntip,S., Schwegler-Berry,D., Scabilloni,J.F., Castranova,V., Antonini,J.M. and Leonard,S.S. (2012) Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats. Journal of Nanomaterials, doi: 10.1155/2012/398302.

Murine Lung Tissue

Ronzani,C., Spiegelhalter,C., Vonesch,J.L., Lebeau,L. and Pons,F. (2012) Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse. Archives of toxicology, 86, 137 - 149.

Human Mesenchymal Stromal Cells

Sadr,N., Pippenger,B.E., Scherberich,A., Wendt,D., Mantero,S., Martin,I. and Papadimitropoulos,A. (2012) Enhancing the biological performance of synthetic polymeric materials by decoration with engineered, decellularized extracellular matrix. Biomaterials, 33, 5085 – 5093.

Pancreatic Stellate Cells

Saito,R., Yamada,S., Yamamoto,Y., Kodera,T., Hara,A., Tanaka,Y., Kimura,F., Takei,I., Umezawa,K. and Kojima,I. (2012) Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats. Endocrinology, 153, 621-630.

Lung Tissue

Sakamoto,K., Hashimoto,N., Kondoh,Y., Imaizumi,K., Aoyama,D., Kohnoh,T., Kusunose,M., Kimura,M., Kawabe,T. and Taniguchi,H. (2012) Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury. American Journal of Physiology-Lung Cellular and Molecular Physiology, 303, L43-L53.

Rat Pancreatic Stellate Cells

Saito,R., Yamada,S., Yamamoto,Y., Kodera,T., Hara,A., Tanaka,Y., Kimura,F., Takei,I., Umezawa,K. and Kojima,I. (2012) Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats. Endocrinology, 153, 621-630.

Murine Bronchoalveolar (BAL) Lavage Fluid

Schneider,D.J., Wu,M., Le,T.T., Cho,S.H., Brenner,M.B., Blackburn,M.R. and Agarwal,S.K. (2012) Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition. The FASEB Journal, 26, 503-512.

Murine Lung

Serra,M.F., Anjos-Valotta,E.A., Olsen,P.C., Couto,G.C., Jurgilas,P.B., Cotias,A.C., Pão,C.R., Ferreira,T.P.T., Arantes,A.C.S. and Pires,A.L.A. (2012) Nebulized Lidocaine Prevents Airway Inflammation, Peribronchial Fibrosis, and Mucus Production in a Murine Model of Asthma. Anesthesiology, 117, 580-591.

Osteoblasts

Shainberg,A.P.M., Valério,P., Zonari,A., Oktar,F.N., Ozyegin,L.S., Leite,M.F. and Goes,A.M. (2012) Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites. Advances in Materials Science and Engineering, doi: 10.1155/2012/650574.

Induced Pluripotent Stem Cell- and Human Embryonic Stem Cell-Derived Fibroblasts

Shamis,Y., Hewitt,K.J., Bear,S.E., Alt-Holland,A., Qari,H., Margvelashvilli,M., Knight,E.B., Smith,A. and Garlick,J.A. (2012) iPSC-derived fibroblasts demonstrate augmented production and assembly of extracellular matrix proteins. In Vitro Cellular & Developmental Biology-Animal, 48, 112 - 122.

Human Patellar Tendon Fibroblasts

Shao,L., Wang,Q. and Dong,Y. (2012) Repetitive mechanical stretching modulates transforming growth factor-induced collagen synthesis and apoptosis in human patellar tendon fibroblasts. Biochemistry and Cell Biology, 90, 667-674.

Murine Lung

Shvedova,A.A., Kapralov,A.A., Feng,W.H., Kisin,E.R., Murray,A.R., Mercer,R.R., Croix,C.M.S., Lang,M.A., Watkins,S.C. and Konduru,N.V. (2012) Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. PLoS One, 7, e30923.

Fibroblasts

Smith,A.M., Hunt,N.C., Shelton,R.M., Birdi,G. and Grover,L.M. (2012) Alginate hydrogel has a negative impact on in vitro collagen 1 deposition by fibroblasts. Biomacromolecules 13, 4032 – 4038.

Biodegradable Collagen Films

Sommer,I. and Kunz,P.M. Improving the water resistance of biodegradable collagen films. Journal of Applied Polymer Science, 125, E27 – E41.

Murine Kidney

Sugiyama,N., Kohno,M. and Yokoyama,T. (2012) Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model. Nephrology Dialysis Transplantation, 27, 1351-1358.

Porcine Kidney

Sullivan,D.C., Mirmalek-Sani,S.H., Deegan,D.B., Baptista,P.M., Aboushwareb,T., Atala,A. and Yoo,J.J. (2012) Decellularization methods of porcine kidneys for whole organ engineering using a high-throughput system. Biomaterials 33, 7756 – 7764.

Osteoblasts

Syberg,S., BrandaoBurch,A., Patel,J.J., Hajjawi,M., Arnett,T.R., Schwarz,P., Jorgensen,N.R. and Orriss,I.R. (2012) Clopidogrel (Plavix), a P2Y12 receptor antagonist, inhibits bone cell function in vitro and decreases trabecular bone in vivo. Journal of Bone and Mineral Research 27, 2373 – 2386. Human Vaginal Smooth Muscle Cells

Takacs,P., Zhang,Y., Candiotti,K., Jaramillo,S. and Medina,C.A. (2012) Effects of PPAR-delta agonist and zinc on vaginal smooth muscle cells collagen and tropoelastin production. International Urogynecology Journal, 23, 1775 - 1779.

Murine Lung Tissue

Takemasa,A., Ishii,Y. and Fukuda,T. (2012) A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice. European Respiratory Journal, doi: 10.1183/09031936.

Human Bone Marrow-Derived Mesenchymal Stem Cells (hMSCs)

Tan,S.L., Ahmad,R.E., Ahmad,T.S., Merican,A.M., Abbas,A.A., Ng,W.M. and Kamarul,T. (2012) Effect of Growth Differentiation Factor 5 on the Proliferation and Tenogenic Differentiation Potential of Human Mesenchymal Stem Cells in vitro. Cells Tissues Organs, 196, 325 - 338.

Smooth Muscle Cells

Thomas,L.V. and Nair,P.D. (2012) Influence of Mechanical Stimulation in the Development of a Medial Equivalent Tissue-Engineered Vascular Construct using a Gelatin-g-Vinyl Acetate Co-Polymer Scaffold. Journal of Biomaterials Science, Polymer Edition, 23, 2069-2087.

Murine Colon Tissue

Thoua,N.M.,Derrett-Smith,E.C., Khan,K., Dooley,A., Shi-Wen,X. and Denton,C.P. (2012) Gut fibrosis with altered colonic contractility in a mouse model of scleroderma. Rheumatology doi: 10.1093/rheumatology/kes191.

Murine Embryo Lung

Tiozzo,C., Carraro,G., Al Alam,D., Baptista,S., Danopoulos,S., Li,A., Lavarreda-Pearce,M., Li,C., De Langhe,S. and Chan,B. (2012) Mesodermal Pten inactivation leads to alveolar capillary dysplasia-like phenotype. The Journal of Clinical Investigation, 122, 3862.

Rat Small Intestine

Totonelli,G., Maghsoudlou,P., Garriboli,M., Riegler,J., Orlando,G., Burns,A.J., Sebire,N.J., Smith,V.V., Fishman,J.M. and Ghionzoli,M. (2012) A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration. Biomaterials 33, 3401 – 3410.

Human Tenocytes

Tucker,R. (2012) Validated Cyclic Shear Stress Significantly Up-Regulates ECM Secretion By Human Tenocytes. Journal of Biomechanics, 45, S437.

Human Alveolar Periosteal Sheets

Uematsu,K., Kawase,T., Nagata,M., Suzuki,K., Okuda,K., Yoshie,H., Burns,D.M. and Takagi,R. (2012) Tissue culture

of human alveolar periosteal sheets using a stem-cell culture medium (MesenPRO-RS): In vitro expansion of CD146-positive cells and concomitant upregulation of osteogenic potential in vivo. Stem Cell Research 10, 1 – 19.

Rat Cardiac Cells (H9C2(2-1))

Umadevi,S., Gopi,V., Simna,S.P., Parthasarathy,A., Yousuf,S.M.J. and Elangovan,V. (2012) Studies on the Cardio Protective Role of Gallic Acid Against AGE-Induced Cell Proliferation and Oxidative Stress in H9C2 (2-1) Cells. Cardiovascular Toxicology, 12, 304 - 311.

Rodent Unilateral Ureteral Obstruction Model

Veerappan,A., Reid,A.C., O'Connor,N., Mora,R., Brazin,J.A., Estaphan,R., Kameue,T., Chen,J., Felsen,D. and Seshan,S. (2012) Mast Cells are Required for the Development of Renal Fibrosis in the Rodent Unilateral Ureteral Obstruction Model. American Journal of Physiology-Renal Physiology 302, F192 - 204.

Human Adipose-Derived Stem Cells

Wang,C., Guo,f.f., Zhou,H., Zhang,Y., Xiao,Z. and Cui,L. (2012) Proteomic profiling of tissue-engineered blood vessel walls constructed by adipose-derived stem cells. Tissue Engineering 19, 415 – 425.

Murine Lung Tissue

Wang,S.D., Lin,L.J., Chen,C.L., Lee,S.C., Lin,C.C., Wang,J.Y. and Kao,S.T. (2012) Xiao-Qing-Long-Tang attenuates allergic airway inflammation and remodeling in repetitive Dermatogoides pteronyssinus challenged chronic asthmatic mice model. Journal of Ethnopharmacology 142, 531 – 538.

Bovine Corneal Endothelial Cells

Wang,T.J., Wang,I., Chen,Y.H., Lu,J.N. and Young,T.H. (2012) Polyvinylidene fluoride for proliferation and preservation of bovine corneal endothelial cells by enhancing type IV collagen production and deposition. Journal of Biomedical Materials Research Part A 100A, 252 – 260.

Lung Tissue

Wang,X., Xia,T., Duch,M.C., Ji,Z., Zhang,H., Li,R., Sun,B., Lin,S., Meng,H. and Liao,Y.P. (2012) Pluronic F108 Coating Decreases the Lung Fibrosis Potential of Multiwall Carbon Nanotubes by Reducing Lysosomal Injury. Nano Letters 12, 3050 – 3061.

Human Foreskin Fibroblasts

Wen,K.C., Fan,P.C., Tsai,S.Y., Shih,I. and Chiang,H.M. (2012) Ixora parviflora Protects against UVB-Induced Photoaging by Inhibiting the Expression of MMPs, MAP Kinases, and COX-2 and by Promoting Type I Procollagen Synthesis. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2012/417346.

Murine Lung Tissue

Wigenstam,E., Jonasson,S., Koch,B. and Bucht,A. (2012) Corticosteroid treatment inhibits airway hyperresponsiveness and lung injury in a murine model of chemical-induced airway inflammation. Toxicology 301, 66 – 71.

Human Smooth Muscle and Mesenchymal Stem Cells

Williams,C., Xie,A.W., Emani,S., Yamato,M., Okano,T., Emani,S.M. and Wong,J.Y. (2012) A Comparison of Human Smooth Muscle and Mesenchymal Stem Cells as Potential Cell Sources for Tissue-Engineered Vascular Patches. Tissue Engineering Part A, 18, 986 – 998.

Decellularised Porcine Dermis and Urinary Bladder Tissue

Wolf,M.T., Daly,K.A., Brennan-Pierce,E.P., Johnson,S.A., Carruthers,C.A., D'Amore,A., Nagarkar,S.P., Velankar,S.S. and Badylak,S.F. (2012) A hydrogel derived from decellularized dermal extracellular matrix. Biomaterials 33, 7028 – 7038.

Murine Dermal Fibroblasts and Skin

Wu,M., Schneider,D.J., Mayes,M.D., Assassi,S., Arnett,F.C., Tan,F.K., Blackburn,M.R. and Agarwal,S.K. (2012) Osteopontin in Systemic Sclerosis and Its Role in Dermal Fibrosis. Journal of Investigative Dermatology, 132, 1605 – 1614.

Regenerated and Native Arteries

Wu,W., Allen,R.A. and Wang,Y. (2012) Fast-degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neoartery. Nature Medicine 18, 1148 – 1153.

Murine Colon Cancer CT-26 Cells

Yan,X., Gardner,T.R., Grieco,M., Herath,S.A.C., Jang,J.H., Kirchoff,D., Njoh,L., Shantha Kumara,H.M.C., Naffouje,S. and Whelan,R.L. (2012) Perioperative polyphenon E-and siliphos-inhibited colorectal tumor growth and metastases without impairment of gastric or abdominal wound healing in mouse models. Surgical Endoscopy, 26, 1856 – 1864.

Cardiac Tissue

Yaniz-Galende,E., Chen,J.Q., Chemaly,E.R., Liang,L., Hulot,J.S., McCollum,L.T., Arias,T., Fuster,V., Zsebo,K. and Hajjar,R.J. (2012) Stem Cell Factor Gene Transfer Promotes Cardiac Repair After Myocardial Infarction via In Situ Recruitment and Expansion of c-kit+ Cells. Circulation Research doi: 10.1161/CIRCRESAHA.111.263830.

Rat Nasal Cavity and Sinus

Yeo,S.W., Bae,S.C., Kim,D.H., Jeon,E.J., Park,S.N. and Park,K.H. (2012) Effects of a TNF-α Antagonist on Rhinosinusitis Model. Otolaryngology--Head and Neck Surgery, 147, 245-246.

Human Lung Tissue

Yasui,M., Miyazaki,Y., Mitaka,K., Ishizuka,M., Unoura,K., Tamaoka,M., Sumi,Y. and Inase,N. (2012) Epithelial-Mesenchymal Transition in Chronic Hypersensitivity Pneumonitis. Journal of medical and dental sciences, 59, 29-41.

Murine Lung

Young,L.R., Gulleman,P.M., Bridges,J.P., Weaver,T.E., Deutsch,G.H., Blackwell,T.S. and McCormack,F.X. (2012) The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. American journal of respiratory and critical care medicine, 186, 1014-1024.

Murine Lung

Zaidi,A., Jelveh,S., Mahmood,J. and Hill,R.P. (2012) Effects of lipopolysaccharide on the response of C57BL/6J mice to whole thorax irradiation. Radiotherapy and Oncology 105, 341 – 349.

Fibroblasts

Zerr,P., Palumbo-Zerr,K., Distler,A., Tomcik,M., Vollath,S., Munoz,L.E., Beyer,C., Dees,C., Egberts,F. and Tinazzi,I. (2012) Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease. Blood doi: 10.1182/blood-2012-01-403428.

Rat Dermal Wound

Zhang,Q., O’Hearn,S., Kavalukas,S.L. and Barbul,A. (2012) Role of High Mobility Group Box 1 (HMGB1) in Wound Healing. Journal of Surgical Research, 176, 343-347.

Murine Alveolar Epithelia

Zhang,X., Zhang,Y., Tao,B., Teng,L., Li,Y., Cao,R., Gui,Q., Ye,M., Mou,X. and Cheng,H. (2012) Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis. The FASEB Journal, 26, 2338-2350.

Murine Airways

Zhao,J., Lloyd,C.M. and Noble,A. (2012) Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling. Mucosal Immunology, doi: 10.1038/mi.2012.76.

Human Dermal Fibroblasts

Zheng,J., Lai,W., Zhu,G., Wan,M., Chen,J., Tai,Y. and Lu,C. (2012) 10Hydroxy2decenoic acid prevents

ultraviolet Ainduced damage and matrix metalloproteinases expression in human dermal fibroblasts. Journal of the European Academy of Dermatology and Venereology doi: 10.1111/j.1468-3083.2012.04707.x.

Murine Lung and Lung Fibroblasts

Zhou,Y., Lee,J.Y., Lee,C.M., Cho,W.K., Kang,M.J., Koff,J.L., Yoon,P.O., Chae,J., Park,H.O. and Elias,J.A. (2012) Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis. Journal of Biological Chemistry, 287, 41991-42000.

Rat Auricular Cartilage Chondrocytes

Zhu,J., Cai,B., Ma,Q., Chen,F. and Wu,W. (2012) Cell bricksenriched plateletrich plasma gel for injectable

cartilage engineeringan in vivo experiment in nude mice. Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.1475.

2011

Human and Murine Left Atria

Adam,O., Theobald,K., Lavall,D., Grube,M., Kroemer,H.K., Ameling,S., Schafers,H.J., Bohm,M. and Laufs,U. (2011) Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation. Journal of Molecular and Cellular Cardiology, 50, 678 – 685.

Murine Lung Tissue Ahangari,F., Takyar,S.S., Lee,C.G., Vasavada,H.H. and Elias,J.A. (2011) Chitotriosidase (Chitinase 1) Plays An

Essential Role In IL-13-Induced Inflammation, Fibrosis And Alternative (M2) Macrophage Activation. American Journal of Respiratory and Critical Care Medicine, 183, A2868.

Murine Lung Tissue

Ahmad,T., Mabalirajan,U., Hasija,K., Ghosh,B. and Agrawal,A. (2011) Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice. International immunopharmacology, 11, 74-78.

Bovine Tendons

Alexander,J.C., Pandit,A., Bao,G., Connolly,D. and Rochev,Y. (2011) Monitoring mRNA in living cells in a 3D in vitro model using TAT-peptide linked molecular beacons. Lab Chip, 11, 3908 – 3914.

Human Skin Fibroblasts

Allanore,Y., Saad,M., DieudéP., Avouac,J., Distler,J.H.W., Amouyel,P., Matucci-Cerinic,M., Riemekasten,G., Airo,P. and Melchers,I. (2011) Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB as Novel Risk Loci for Systemic Sclerosis. PLoS Genetics, 7, e1002091.

Human Fetal Cardiac Fibroblasts

Alvarez,D., Briassouli,P., Clancy,R.M., Zavadil,J., Reed,J.H., Abellar,R.G., Halushka,M., Fox-Talbot,K., Barrat,F.J. and Buyon,J.P. (2011) A Novel Role of Endothelin-1 in Linking Toll-like Receptor 7-mediated Inflammation to Fibrosis in Congenital Heart Block. Journal of Biological Chemistry, 286, 30444-30454.

Human Dental Pulp Cells

Anpo,M., Shirayama,K. and Tsutsui,T. (2011) Cytotoxic effect of eugenol on the expression of molecular markers related to the osteogenic differentiation of human dental pulp cells. Odontology, 99, 188 – 192.

Bovine Intramuscular Fibroblasts

Archile-Contreras,A.C., Cha,M.C., Mandell,I.B., Miller,S.P. and Purslow,P.P. (2011) Vitamins E and C May Increase Collagen Turnover by Intramuscular Fibroblasts. Potential for Improved Meat Quality. Journal of agricultural and food chemistry 59, 608 – 614.

Rat Renal Cortical Tissue

Asanuma,H., Vanderbrink,B.A., Campbell,M.T., Hile,K.L., Zhang,H., Meldrum,D.R. and Meldrum,K.K. (2011) Arterially delivered mesenchymal stem cells prevent obstruction-induced renal fibrosis. Journal of Surgical Research, 168, e51-e59.

Rat Endomyocardial Samples

Ayala,P., Montenegro,J., Vivar,R., Letelier,A., Urroz,P.A., Copaja,M., Pivet,D., Humeres,C., Troncoso,R. and Vicencio,J.M. (2011) Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol. Experimental and Molecular Pathology 92, 97 – 104.

Murine Lung Tissue

Atochina-Vasserman,E.N., Bates,S.R., Zhang,P., Abramova,H., Zhang,Z., Gonzales,L., Tao,J.Q., Gochuico,B.R., Gahl,W. and Guo,C.J. (2011) Early Alveolar Epithelial Dysfunction Promotes Lung Inflammation in a Mouse Model of Hermansky Pudlak Syndrome. American Journal of Respiratory and Critical Care Medicine, 184, 449 – 458.

Porcine Aortic Valve Cusps

Balachandran,K., Hussain,S., Yap,C.H., Padala,M., Chester,A.H. and Yoganathan,A.P. (2011) Elevated cyclic stretch and serotonin result in altered aortic valve remodeling via a mechanosensitive 5-HT2A receptor-dependent pathway. Cardiovascular Pathology, doi: 10.1016/j.carpath.2011.07.005.

Murine Cardiac Ventricular Fibroblasts

Benamer,N., Fares,N., Bois,P. and Faivre,J.F. (2011) Electrophysiological and Functional effects of sphingosine-1-phosphate in mouse ventricular fibroblasts. Biochemical and Biophysical Research Communications, 408, 6 – 11.

Murine Lung Tissue

Bitencourt,C.S., Pereira,P.A.T., Ramos,S.G., Sampaio,S.V., Arantes,E.C., Aronoff,D.M. and Faccioli,L.H. (2011) Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis. Fibrogenesis & Tissue Repair, 4, 3.

Murine Lung Tissue

Bogatkevich,G.S., Ludwicka Bradley,A., Nietert,P.J., Akter,T., van Ryn,J. and Silver,R.M. (2011) Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease. Arthritis & Rheumatism, 63, 1416-1425.

Rat Renal Fibroblasts

Boor,P., Celec,P., Martin,I.V., Villa,L., Hodosy,J., KlenovicsováK., Esposito,C., Schäfer,S., Albrecht-Küpper,B. and Ostendorf,T. (2011) The peroxisome proliferator-activated receptor- agonist, BAY PP1, attenuates renal fibrosis in rats. Kidney International 80, 1182 – 1197.

Human Archeological Bones

Caputo,I., Lepretti,M., Scarabino,C., Esposito,C. and Proto,A. (2011) An acetic acid-based extraction method to obtain high quality collagen from archeological bone remains. Analytical Biochemistry, http://dx.doi.org/10.1016/j.ab.2011.10.024.

Human Lung Tissue

Carnesecchi,S., Deffert,C., Donati,Y., Basset,O., Hinz,B., Preynat-Seauve,O., Guichard,C., Arbiser,J.L., Banfi,B. and Pache,J.C. (2011) A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxidants & Redox Signaling 15, 607 – 619.

Murine Lung Tissue

Chen,C.M., Wu,M.Y., Chou,H.C., Lang,Y.D. and Wang,L.F. (2011) Downregulation of Caveolin-1 in a Murine Model of Acute Allergic Airway Disease. Pediatrics & Neonatology, 52, 5 – 10.

Human Fibroblasts

Chiang,H.M., Lin,T.J., Chiu,C.Y., Chang,C.W., Hsu,K.C., Fan,P.C. and Wen,K.C. (2011) Coffea Arabica extract and its constituents prevent photoaging by suppressing MMPs expression and MAP kinase pathway. Food and Chemical Toxicology, 49, 309-318.

Human Adipose Tissue Stem Cells

Choi,J.S., Kim,B.S., Kim,J.D., Choi,Y.C., Lee,H.Y. and Cho,Y.W. (2011) In Vitro Cartilage Tissue Engineering Using Adipose-Derived Extracellular Matrix Scaffolds Seeded with Adipose-Derived Stem Cells. Tissue Engineering Part A, 18, 80 – 92.

Human Adipose Tissue

Choi,J.S., Kim,B.S., Kim,J.Y., Kim,J.D., Choi,Y.C., Yang,H.J., Park,K., Lee,H.Y. and Cho,Y.W. (2011) Decellularized extracellular matrix derived from human adipose tissue as a potential scaffold for allograft tissue engineering. Journal of Biomedical Materials Research Part A 97A, 292 – 299.

Rat Hepatic Stellate Cells

Chong,L.W., Hsu,Y.C., Chiu,Y.T., Yang,K.C. and Huang,Y.T. (2011) Antifibrotic Effects of Triptolide on Hepatic

Stellate Cells and Dimethylnitrosamineintoxicated Rats. Phytotherapy Research 25, 990 – 999.

Rat Right Ventricle

Choudhary,G., Troncales,F., Martin,D., Harrington,E.O. and Klinger,J.R. (2011) Bosentan Attenuates Right Ventricular Hypertrophy and Fibrosis in Normobaric Hypoxia Model of Pulmonary Hypertension. The Journal of Heart and Lung Transplantation, 30, 827 – 833.

Human Colonic Myofibroblasts (HCMFs)

Chrysanthopoulou,A., Mitroulis,I., Kambas,K., Skendros,P., Kourtzelis,I., Vradelis,S., Kolios,G., Aslanidis,S.,

Doumas,M. and Ritis,K. (2011) Tissue factorthrombin signaling enhances the fibrotic activity of

myofibroblasts in systemic sclerosis through upregulation of endothelin receptor A. Arthritis & Rheumatism, 63, 3586-3597.

Neonatal Mice Cardiac Fibroblasts

Chu,W.F., Li,X.X., Li,C., Wan,L., Shi,H., Song,X.H., Liu,X.Y., Chen,X., Zhang,C. and Shan,H.L. (2011) TGFBR3, a

potential negative regulator of TGF-β signaling, protects cardiac fibroblasts from hypoxiainduced apoptosis. Journal of cellular physiology, 226, 2586-2594.

Rat Hepatic Stellate Cells (HSC-6)

Chuang,H.Y., Ng,L.T., Lin,L.T., Chang,J.S., Chen,J.Y., Lin,T.C. and Lin,C.C. (2011) Hydrolysable tannins of tropical

almond show antifibrotic effects in TGFβinduced hepatic stellate cells. Journal of the Science of Food and Agriculture 91, 2777 – 2784.

Ti6Al7Nb Alloy

Cimenoglu,H., Meydanoglu,O., Baydogan,M., Bermek,H., Huner,P. and Kayali,E.S. (2011) Characterization of thermally oxidized Ti6Al7Nb alloy for biological applications. Metals and Materials International, 17, 765-770.

Human Lung Fibroblasts

Conte,E., Fruciano,M., Fagone,E., Gili,E., Caraci,F., Iemmolo,M., Crimi,N. and Vancheri,C. (2011) Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms. PloS one, 6, e24663.

Rat Lung Tissue

Cui,Y.,Robertson,J., Maharaj,S., Waldhauser,L., Niu,J., Wang,J., Farkas,L., Kolb,M. and Gauldie,J. (2011) Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis. The International Journal of Biochemistry & Cell Biology, 43, 1122 – 1133.

Rat Lung Tissue

Curley,G.F., Contreras,M., Higgins,B., O'Kane,C., McAuley,D.F., O'Toole,D. and Laffey,J.G. (2011) Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat. Anesthesiology, 115, 1022 – 1032.

Murine Lung Tissue

Dackor,R.T., Cheng,J., Voltz,J.W., Card,J.W., Ferguson,C.D., Garrett,R.C., Bradbury,J.A., DeGraff,L.M., Lih,F.B. and Tomer,K.B. (2011) Prostaglandin E2 protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction. American Journal of Physiology-Lung Cellular and Molecular Physiology, 301, L645-L655.

Murine Small Renal Arteries

Debrah,D.O., Debrah,J.E., Haney,J.L., McGuane,J.T., Sacks,M.S., Conrad,K.P. and Shroff,S.G. (2011) Relaxin regulates vascular wall remodeling and passive mechanical properties in mice. Journal of Applied Physiology, 111, 260.

Undetermined Model

de Cogan,F., Booth,A., Gough,J.E. and Webb,S.J. (2011) Conversion of Magnetic Impulses into Cellular Responses by

SelfAssembled NanoparticleVesicle Hydrogels. Angewandte Chemie International Edition 50, 12290 – 12293.

Human Dermal Fibroblasts

Dees,C., Tomcik,M., Zerr,P., Akhmetshina,A., Horn,A., Palumbo,K., Beyer,C., Zwerina,J., Distler,O. and Schett,G. (2011) Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis. Annals of the Rheumatic Diseases, 70, 1304.

Skin Samples and Cell Culture Supernatants

Dees,C., Akhmetshina,A., Zerr,P., Reich,N., Palumbo,K., Horn,A., Jüngel,A., Beyer,C., Kr÷nke,G. and Zwerina,J. (2011) Platelet-derived serotonin links vascular disease and tissue fibrosis. The Journal of Experimental Medicine, 208, 961 – 972.

Human Dermal Fibroblasts

Dees,C., Tomcik,M., Zerr,P., Akhmetshina,A., Horn,A., Palumbo,K., Beyer,C., Zwerina,J., Distler,O. and Schett,G. (2011) Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis. Annals of the Rheumatic Diseases, doi: 10.1136/ard.2010.134742.

Human Gut Mucosa

Di Sabatino,A., Battista,N., Biancheri,P., Rapino,C., Rovedatti,L., Astarita,G., Vanoli,A., Dainese,E., Guerci,M. and Piomelli,D. (2011) The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease. Mucosal Immunology, 4, 574-583.

Murine Lung Tissue

Ditt,V., Lüsebrink,J., Tillmann,R.L., Schildgen,V., Schildgen,O. and Martin,D. (2011) Respiratory Infections by HMPV and RSV Are Clinically Indistinguishable but Induce Different Host Response in Aged Individuals. PloS one, 6, 719-724.

Self-Assembled Articular Cartilage Constructs

Eleswarapu,S.V., Chen,J.A. and Athanasiou,K.A. (2011) Temporal assessment of ribose treatment on self-assembled articular cartilage constructs. Biochemical and Biophysical Research Communications 414, 431 – 436.

Murine Lung Tissue

Fritz,D.K., Kerr,C., Fattouh,R., Llop-Guevara,A., Khan,W.I., Jordana,M. and Richards,C.D. (2011) A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent. The Journal of Immunology, 186, 1107.

Lung Tissue

Gaggini,F., Laleu,B., Orchard,M., Fioraso-Cartier,L., Cagnon,L., Houngninou-Molango,S., Gradia,A., Duboux,G., Merlot,C. and Heitz,F. (2011) Design, Synthesis and Biological Activity of Original Pyrazolo-Pyrido-Diazepine,-Pyrazine and-Oxazine Dione Derivatives as Novel Dual Nox4/Nox1 inhibitors. Bioorganic & Medicinal Chemistry 19, 6989 – 6999.

Murine Lung Tissue

Gan,Y., Reilkoff,R., Peng,X., Russell,T., Chen,Q., Mathai,S.K., Homer,R., Gulati,M., Siner,J. and Elias,J. (2011) Role of semaphorin 7a signaling in TGF 1 induced lung fibrosis and scleroderma related interstitial lung disease. Arthritis & Rheumatism, 63, 2484 – 2494.

Murine Lung Tissue

Gan,Y., Reilkoff,R., Peng,X., Russell,T., Chen,Q., Mathai,S.K., Homer,R., Gulati,M., Siner,J. and Elias,J. (2011) Role of semaphorin 7a signaling in TGF 1 induced lung fibrosis and scleroderma related interstitial lung disease. Arthritis & Rheumatism, 63, 2484 – 2494.

Murine Lung Tissue

Garibaldi,B.T., D'Alessio,F.R., Files,D.C., Mock,J., Chau,E., Sidhaye,V. and King,L. (2011) Regulatory T Cell Depletion Increases CXCL12-Dependent Fibroproliferation After LPS Injury. American Journal of Respiratory and Critical Care Medicine, 183, A3982.

Murine Lung Tissue

Gasse,P., Riteau,N., Vacher,R., Michel,M.L., Fautrel,A., di Padova,F., Fick,L., Charron,S., Lagente,V. and Eberl,G. (2011) IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis. PloS one, 6, e23185.

Murine Heart Tissue

Georgescu,S.P., Aronovitz,M.J., Iovanna,J.L., Patten,R.D., Kyriakis,J.M. and Goruppi,S. (2011) Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8. American Journal of Physiology-Cell Physiology, 301, C1046-C1056.

Human Lung Tissue

Gibbons,M.A., MacKinnon,A.C., Ramachandran,P., Dhaliwal,K., Duffin,R., Phythian-Adams,A.T., van Rooijen,N., Haslett,C., Howie,S.E. and Simpson,A.J. (2011) Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis. American Journal of Respiratory and Critical Care Medicine, 184, 569.

Human Carotic Plaques

Goncalves,I., Stollenwerk,M.M., Lindholm,M.W., Dias,N., Pedro,L.M., Moses,J., Fredrikson,G.N., Nilsson,J. and Ares,M.P.S. (2011) Activator protein-1 in carotid plaques is related to cerebrovascular symptoms and cholesteryl ester content. Cardiovascular Pathology, 20, 36-43.

Human Adipose Tissue-Derived Stem Cells

Gomide,V., Zonari,A.A.C., Breyner,N.M., de Goes,A.M. and Pereira,M.M. (2011) Attachment and Proliferation of Human-Adipose-Tissue-Derived Stem Cells on Bioactive Glass/PVA Hybrid Scaffolds. ISRN Materials Science, doi: 10.5402/2011/240864.

Murine Lung Homogenate

González-López,A., Astudillo,A., Garcia-Prieto,E., Fernández-García,M.S., López-Vazquez,A., Batalla-Solís,E., Taboada,F., Fueyo,A. and Albaiceta,G.M. (2011) Inflammation and Matrix remodelling during repair of Ventilator-induced lung injury. American Journal of Physiology-Lung Cellular and Molecular Physiology, 301, L500-L509.

Murine Colon Tissue

Guan,Q., Ma,Y., Hillman,C.L., Qing,G., Ma,A.G., Weiss,C.R., Zhou,G., Bai,A., Warrington,R.J. and Bernstein,C.N. (2011) Targeting IL-12/IL-23 by employing a p40 peptide-based vaccine ameliorates TNBS-induced acute and chronic murine colitis. Molecular Medicine, 17, 646.

Murine Lung Tissue

Hoyles,R.K., Derrett-Smith,E.C., Khan,K., Shiwen,X., Howat,S.L., Wells,A.U., Abraham,D.J. and Denton,C.P. (2011) An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor {beta} Receptor. American Journal of Respiratory and Critical Care Medicine, 183, 249.

Murine Myofibroblasts

Huang,X., Gai,Y., Yang,N., Lu,B., Samuel,C.S., Thannickal,V.J. and Zhou,Y. (2011) Relaxin Regulates Myofibroblast Contractility and Protects against Lung Fibrosis. The American Journal of Pathology, http://dx.doi.org/10.1016/j.ajpath.2011.08.018.

Murine Diaphragm

Huang,P., Cheng,G., Lu,H., Aronica,M., Ransohoff,R.M. and Zhou,L. (2011) Impaired respiratory function in mdx and mdx/utrn+/- mice. Muscle & Nerve, 43, 263-267.

Human Fibroblasts

Imaizumi,K., Hashimoto,N., Hashimoto,I., Imai,N., Tomita,Y., Kounou,T., Sakamoto,K., Aoyama,D., Ogawa,M.T. and Kusunose,S.I. (2011) The Role Of Interleukin-17/th17 In Human Interstitial Pneumonia. Am J Respir Crit Care Med, 183, A4282.

Murine Lung Tissue

Imazu,Y., Yanagi,S., Miyoshi,K., Tsubouchi,H., Yamashita,S., Matsumoto,N., Ashitani,J., Kangawa,K. and Nakazato,M. (2011) Ghrelin ameliorates bleomycin-induced acute lung injury by protecting alveolar epithelial cells and suppressing lung inflammation. European Journal of Pharmacology 672, 153 – 158.

Fibroblasts

Iyer,P., Walker,K.J. and Madihally,S.V. (2011) Increased matrix synthesis by fibroblasts with decreased proliferation

on synthetic chitosangelatin porous structures. Biotechnology and Bioengineering doi: 10.1002/bit.24396.

Decellularised Porcine-Heart Valves and Autologous Endothelial Progenitor Cell Derived Endothelial Cells

Jordan,J.E., Williams,J.K., Lee,S.J., Raghavan,D., Atala,A. and Yoo,J.J. (2011) Bioengineered self-seeding heart valves. The Journal of Thoracic and Cardiovascular Surgery 143, 201 – 208.

Human Periodontal Ligament Stem cells (hPDLSCs)

Jung,I.H., Park,J.C., Kim,J.C., Jeon,D.W., Choi,S.H., Cho,K.S., Im,G.I., Kim,B.S. and Kim,C.S. (2011) Novel Application of Human Periodontal Ligament Stem Cells and Water-Soluble Chitin for Collagen Tissue Regeneration: In Vitro and In Vivo Investigations. Tissue Engineering Part A, doi: 10.1089/ten.tea.2011.0164.

Murine Lung Tissue

Kamata,H., Tasaka,S., Inoue,K., Miyamoto,K., Nakano,Y., Shinoda,H., Kimizuka,Y., Fujiwara,H., Ishii,M. and Hasegawa,N. (2011) Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice. Experimental Biology and Medicine, 236, 315.

Myofibroblasts

Kambas,K., Chrysanthopoulou,A., Kourtzelis,I., Skordala,M., Mitroulis,I., Rafail,S., Vradelis,S., Sigalas,I., Wu,Y.Q. and Speletas,M. (2011) Endothelin-1 Signaling Promotes Fibrosis In Vitro in a Bronchopulmonary Dysplasia Model by Activating the Extrinsic Coagulation Cascade. The Journal of Immunology, 186, 6568.

Murine Dorsal Tissue

Kavalukas,S.L., Uzgare,A.R., Bivalacqua,T.J. and Barbul,A. (2011) Arginase inhibition promotes wound healing in mice. Surgery, http://dx.doi.org/10.1016/j.surg.2011.07.012.

Murine Skin and Lung

Kavian,N., Servettaz,A., Marut,W., Nicco,C., Chéreau,C., Weill,B. and Batteux,F. (2011) Sunitinib inhibits the

phosphorylation of PDGFreceptor beta in the skin of mice with sclerodermalike features and prevents the development of the disease. Arthritis & Rheumatism, doi: 10.1002/art.34354.

Murine Tissue and Cultured Mesangial Cells

Kang,Y.S., Lee,M.H., Song,H.K., Hyun,Y.Y., Cha,J.J., Ko,G.J., Kim,S.H., Lee,J.E., Han,J.Y. and Cha,D.R. (2011) Aliskiren improves insulin resistance and ameliorates diabetic vascular complications in db/db mice. Nephrology Dialysis Transplantation, 26, 1194 – 1204.

Human Myocardial Tissue

Kasner,M., Westermann,D., Lopez,B., Gaub,R., Escher,F., Kuhl,U., Schultheiss,H.P. and Tschope,C. (2011) Diastolic Tissue Doppler Indexes Correlate With the Degree of Collagen Expression and Cross-Linking in Heart Failure and Normal Ejection Fraction. Journal of the American College of Cardiology, 57, 977-985.

Rat and Murine Lung Tissue

Kass,D., Loh,K., Borczuk,A., Tedrow,J., Juan Guardela,B., Kaminski,N. and Greenberg,S. (2011) Cytokine-Like Factor I (CLF1) Expression Is Increased In Idiopathic Pulmonary Fibrosis (IPF) And Promotes Inflammation But Decreases Fibrosis In Bleomycin Injury. American Journal of Respiratory and Critical Care Medicine, 183, A2710.

Murine Lung Tissue

Kearley,J., Erjefalt,J.S., Andersson,C., Benjamin,E., Jones,C.P., Robichaud,A., Pegorier,S., Brewah,Y., Burwell,T.J. and Bjermer,L. (2011) IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. American Journal of Respiratory and Critical Care Medicine, 183, 865.

Lung Tissue

Kelly,M.M., Hasan,S.A., Gwozd,C., Kooi,C. and Oyelusi,W. (2011) Corticosteroid Treatment Significantly Reduces Neutrophilic Airway Inflammation And Remodeling In A Model Of Severe Asthma. American Journal of Respiratory and Critical Care Medicine, 183, A2544.

Murine Lung Tissue

Khalifah,A.P., Young,S.K., Campbell,M., Briones,N., Yamashita,C. and Downey,G.P. (2011) Protein Tyrosine Phosphatase-± Deficiency In Mice Protects Against Bleomycin-Induced Lung Fibrosis And Causes Aberrant Response To TGF {superscript 2}. American Journal of Respiratory and Critical Care Medicine, 183, A6431.

Human Marrow Derived Stromal Cells

Khan,M.R., Donos,N., Salih,V. and Brett,P.M. (2011) The enhanced modulation of key bone matrix components by modified Titanium implant surfaces. Bone, doi: 10.1016/j.bone.2011.07.040.

Chondrocytes

Khanarian,N.T., Jiang,J., Wan,L.Q., Mow,V.C. and Lu,H.H. (2011) A Hydrogel-Mineral Composite Scaffold for Osteochondral Interface Tissue Engineering. Tissue Engineering, Part A, doi: 10.1089/ten.TEA.2011.0279.

Murine Lung Tissue

Kim,D.Y., Kwon,E.Y., Hong,G.U., Lee,Y.S., Lee,S.H. and Ro,J.Y. (2011) Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells. Respiratory Research, 12, 49.

Murine Skin Tissue

Kim,S.E., Lee,J.O., Kwon,H.B., Ahn,B.J. and Lee,A-Y. (2011) Greater Collagen Deposition with the Microneedle Therapy System Than with Intense Pulsed Light. Dermatologic Surgery 37, 336 – 341.

Murine Lung Tissue

Kim,T.H., Kim,S.H., Seo,J.Y., Chung,H., Kwak,H.J., Lee,S.K., Yoon,H.J., Shin,D.H., Park,S.S. and Sohn,J.W. (2011) Blockade of the Wnt/ β-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis. The Tohoku Journal of Experimental Medicine, 223, 45-54.

Murine and Human Lung Fibroblasts

Kitamura,H., Cambier,S., Somanath,S., Barker,T., Minagawa,S., Markovics,J., Goodsell,A., Publicover,J., Reichardt,L. and Jablons,D. (2011) Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest. 121, 2863 – 2875.

Murine Lung Tissue

Kneidinger,N., Yildirim,A.O., Callegari,J., Takenaka,S., Stein,M.M., Dumitrascu,R., Bohla,A., Bracke,K.R., Morty,R.E. and Brusselle,G.G. (2011) Activation of the WNT/β-Catenin Pathway Attenuates Experimental Emphysema. American Journal of Respiratory and Critical Care Medicine, 183, 723.

Human Auricular Perichondrium

Kobayashi,S., Takebe,T., Inui,M., Iwai,S., Kan,H., Zheng,Y.W., Maegawa,J. and Taniguchi,H. (2011) Reconstruction of human elastic cartilage by a CD44+ CD90+ stem cell in the ear perichondrium. Proceedings of the National Academy of Sciences, 108, 14479-14484.

Porcine Annulus Fibrosus Cells

Koepsell,L., Remund,T., Bao,J., Neufeld,D., Fong,H. and Deng,Y. Tissue engineering of annulus fibrosus using electrospun fibrous scaffolds with aligned polycaprolactone fibers. Journal of Biomedical Materials Research Part A, doi: 10.1002/jbm.a.33216.

Primary Porcine Annulus Fibrosus Cells

Koepsell,L., Zhang,L., Neufeld,D., Fong,H. and Deng,Y. (2011) Electrospun nanofibrous polycaprolactone scaffolds for tissue engineering of annulus fibrosus. Macromolecular bioscience, 11, 391 – 399.

Murine Lung Tissue

Kramer,E.L., Hardie,W.D., Mushaben,E.M., Acciani,T.H., Pastura,P.A., Korfhagen,T.R., Hershey,G.K., Whitsett,J.A. and Le Cras,T.D. (2011) Rapamycin Decreases Airway Remodeling and Hyperreactivity in a Transgenic Model of Noninflammatory Lung Disease. Journal of Applied Physiology, doi: 10.1152/japplphysiol.00737.2011.

Lung Fibroblasts

Lam,A.P., Sennello,J.A., Flozak,A.S., Russell,S.R. and Gottardi,C.J. (2011) Loss Of Wnt/beta-Catenin Signaling Alters Lung Fibroblast Response To Fibrotic Injury. American Journal of Respiratory and Critical Care Medicine, 183, A2702.

Rat Kidney Tissue

Lan,H., Yanfei,Q., Xianglu,R., Jianmin,J., Qinglin,Y., Johji,Y., Michael,M. and Yuhao,L. (2011) The Ayurvedic Medicine Salacia oblonga Attenuates Diabetic Renal Fibrosis in Rats: Suppression of Angiotensin II/AT1 Signaling. Evidence-Based Complementary and Alternative Medicine, doi: 10.1093/ecam.nep095.

Human Adult Hepatocytes

Lang,R., Stern,M.M., Smith,L., Liu,Y., Bharadwaj,S., Liu,G., Baptista,P.M., Bergman,C.R., Soker,S. and Yoo,J.J. (2011) Three-dimensional culture of hepatocytes on porcine liver tissue-derived extracellular matrix. Biomaterials, 32, 7042 – 7052.

Fibroblasts

Lecca,M.R., Maag,C., Berger,E.G. and Hennet,T. (2011) Fibrotic response in fibroblasts from congenital disorders of glycosylation. Journal of Cellular and Molecular Medicine, 15, 1788-1796.

Nasal Polyp-Derived Fibroblasts

Lee,H.M., Park,I.H., Choi,H. and Kim,Y.D. (2011) Effect Of Caffeic Acid On Myofibroblast Differentiation And Collagen Production In Nasal Polyp-Derived Fibroblast. American Journal of Respiratory and Critical Care Medicine, 183, A2806.

Rat Lung Tissue

Lee,S.H., Jang,A.S., Kwon,J.H., Park,S.K., Won,J.H. and Park,C.S. (2011) Mesenchymal Stem Cell Transfer Suppresses Airway Remodeling in a Toluene Diisocyanate-Induced Murine Asthma Model. Allergy, Asthma & Immunology Research, 3, 205.

Human Dermal Fibroblasts

Lee,T.H., Lee,S.M., Lee,D.Y., Son,Y., Chung,D.K., Baek,N.I. and Kim,J. (2011) A glycosidic spinasterol from Koreana stewartia promotes procollagen production and inhibits matrix metalloproteinase-1 expression in UVB-irradiated human dermal fibroblasts. Biological & Pharmaceutical Bulletin, 34, 768-773.

Ligament-Bone (LTB) Relevant Cells

Lee,J., Choi,W.I., Tae,G., Kim,Y.H., Kang,S.S., Kim,S.E., Kim,S.H., Jung,Y. and Kim,S.H. (2011) Enhanced regeneration of the ligament–bone interface using a poly(l-lactide–co-ε-caprolactone) scaffold with local delivery of cells/BMP-2 using a heparin-based hydrogel. Acta Biomaterialia, 7, 244 – 257.

Human Osteoblastic MG63 Cells

Li,J., Wei,L., Sun,J. and Guan,G. (2011) Effect of ionic products of dicalcium silicate coating on osteoblast differentiation and collagen production via TGF-β pathway. Journal of Biomaterials Applications doi: 10.1177/08853282114/6393.

Murine Lung Tissue

Li,M., Krishnaveni,M.S., Li,C., Zhou,B., Xing,Y., Banfalvi,A., Li,A., Lombardi,V., Akbari,O. and Borok,Z. (2011) Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis. J Clin Invest., 121, 277 – 287.

Human Fibroblasts

Lindahl,K., Barnes,A.M., FratzlZelman,N., Whyte,M.P., Hefferan,T.E., Makareeva,E., Brusel,M., Yaszemski,M.J.,

Rubin,C.J. and Kindmark,A. (2011) COL1 Cpropeptide cleavage site mutations cause high bone mass osteogenesis imperfecta. Human Mutation 32, 598 – 609.

Rat Hepatic Stellate Cells

Lo,Y.T., Tsai,Y.H., Wu,S.J., Chen,J.R. and Chao,J.C.J. (2011) Ginsenoside Rb1 Inhibits Cell Activation and Liver Fibrosis in Rat Hepatic Stellate Cells. Journal of Medicinal Food 14, 1135 – 1143.

Murine Fibroblasts

Lu,H., Hoshiba,T., Kawazoe,N. and Chen,G. (2011) Autologous extracellular matrix scaffolds for tissue engineering. Biomaterials, 32, 2489 – 2499.

Primary Mouse Lung Fibroblasts

Luchsinger,L.L., Patenaude,C.A., Smith,B.D. and Layne,M.D. (2011) Myocardin Related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts. Journal of Biological Chemistry, doi 10.1074/jbc.M111.276931.

Murine Lung

Luckhardt,T.R., Coomes,S.M., Trujillo,G., Stoolman,J.S., Vannella,K.M., Bhan,U., Wilke,C.A., Moore,T.A., Toews,G.B. and Hogaboam,C. (2011) TLR9-induced interferon is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis. Fibrogenesis & Tissue Repair, 4, 18.

Murine Lung Tissue

Luzina,I.G., Lockatell,V., Todd,N.W., Keegan,A.D., Hasday,J.D. and Atamas,S.P. (2011) Splice isoforms of human interleukin 4 are functionally active in mice in vivo. Immunology 132, 385 – 393.

Murine Lung Tissue

Luzina,I.G., Lockatell,V., Todd,N.W., Highsmith,K., Keegan,A.D., Hasday,J.D. and Atamas,S.P. (2011) Alternatively spliced variants of interleukin-4 promote inflammation differentially. Journal of leukocyte biology, 89, 763.

Lung Tissue

Madala,S., Davidson,C., Schmidt,S., LeCras,T., Korfhagen,T., Ikegami,M. and Hardie,W. (2011) Pharmacologic Inhibition Of MEK Reverses Transforming Growth Factor-Alpha Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 183, A5979.

Rat Lung Tissue

Mahmood,J., Jelveh,S., Calveley,V., Zaidi,A., Doctrow,S.R. and Hill,R.P. (2011) Mitigation of Lung Injury after Accidental Exposure to Radiation. Radiation Research 176, 770 – 780.

Murine Lung Tissue

Manali,E., Moschos,C., Triantafillidou,C., Kotanidou,A., Psallidas,I., Karabela,S., Roussos,C., Papiris,S., Armaganidis,A. and Stathopoulos,G. (2011) Static and dynamic mechanics of the murine lung after intratracheal bleomycin. BMC Pulmonary Medicine, 11, 33.

Osteoblastic MC3T3-E1 Cell Cultures

Manzano,M., Lozano,D., Arcos,D., Portal-N· ez,S., Orden,C.L., Esbrit,P. and Vallet-RegíM. (2011) Comparison of the osteoblastic activity conferred on Si-doped hydroxyapatite scaffolds by different osteostatin coatings. Acta Biomaterialia, 7, 3555 – 3562.

Human Mesenchymal Stromal/Stem Cells

Mariner,P.D., Johannesen,E. and Anseth,K.S. (2011) Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds. Journal of Tissue Engineering and Regenerative Medicine doi: 10.1002/term.435.

Rat Joint Regions and Non-Joint Regions of Median and Sciatic Nerves

Mason,S. and Phillips,J.B. (2011) An ultrastructural and biochemical analysis of collagen in rat peripheral nerves: the relationship between fibril diameter and mechanical properties. Journal of the Peripheral Nervous System, 16, 261-269.

Murine Model of Chronic Eosinophilic Ileitis

Masterson,J.C., McNamee,E.N., Jedlicka,P., Fillon,S., Ruybal,J., Hosford,L., Rivera-Nieves,J., Lee,J.J. and Furuta,G.T. (2011) CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling. The American Journal of Pathology 179, 2302 – 2314.

Lung Tissue

McCart,E., Day,R.M. and Mungunsukh,O. (2011) Effect Of Exogenous Hgf And Nk2 Expression In A Bleomycin Model Of Pulmonary Fibrosis. Am J Respir Crit Care Med, 183, A5994.

Murine Distal Ileum

McLarren,K.W., Cole,A.E., Weisser,S.B., Voglmaier,N.S., Conlin,V.S., Jacobson,K., Popescu,O., Boucher,J.L. and Sly,L.M. (2011) SHIP-Deficient Mice Develop Spontaneous Intestinal Inflammation and Arginase-Dependent Fibrosis. The American Journal of Pathology, 179, 180 – 188.

Rodent Lung Tissue

McDonald,J., Doyle-Eisele,M., Sheller,M., Crowther,R. and Liu,Y. (2011) AZX100, An HSP20 Mimic, Decreases Fibrosis And Alters The Circadian Rhythm And Cytoskeleton Remodeling Molecular Pathways In The Bleomycin Induced Fibrosis Model. American Journal of Respiratory and Critical Care Medicine, 183, A6444.

Murine Distal Ileum

McLarren,K.W., Cole,A.E., Weisser,S.B., Voglmaier,N.S., Conlin,V.S., Jacobson,K., Popescu,O., Boucher,J.L. and Sly,L.M. (2011) SHIP-Deficient Mice Develop Spontaneous Intestinal Inflammation and Arginase-Dependent Fibrosis. The American Journal of Pathology, doi: 10.1016/j.ajpath.2011.03.018.

Alveolar Epithelial Cells

Mi,S., Li,Z., Yang,H.Z., Liu,H., Wang,J.P., Ma,Y.G., Wang,X.X., Liu,H.Z., Sun,W. and Hu,Z.W. (2011) Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1β-Dependent and -Independent Mechanisms. The Journal of Immunology, 187, 3003-3014.

Murine Lung

Mitaka,K., Miyazaki,Y., Yasui,M., Furuie,M., Miyake,S., Inase,N. and Yoshizawa,Y. (2011) Th2-Biased Immune Responses Are Important in a Murine Model of Chronic Hypersensitivity Pneumonitis. International archives of allergy and immunology, 154, 264-274.

Lung Tissue

Mungunsukh,O., McCart,E. and Day,R.M. (2011) Effect Of Exogenous HGF And NK2 Expression In A Bleomycin Model Of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 183, A5994.

Murine Lower Muscle

Nevo,Y., Aga-Mizrachi,S., Elmakayes,E., Yanay,N., Ettinger,K., Elbaz,M., Brunschwig,Z., Dadush,O., Elad-Sfadia,G. and Haklai,R. (2011) The Ras Antagonist, Farnesylthiosalicylic Acid (FTS), Decreases Fibrosis and Improves Muscle Strength in dy2J/dy2J Mouse Model of Muscular Dystrophy. PLoS One 6(3): e18049.

Murine Lung Tissue

Nicola,T., Ambalavanan,N., Zhang,W., James,M.L., Rehan,V.K., Halloran,B.A., Olave,N., Bulger,A., Oparil,S. and Chen,Y.F. (2011) Hypoxia-Induced Inhibition of Lung Development is Attenuated by the Peroxisome Proliferator-Activated Receptor- γAgonist Rosiglitazone. American Journal of Physiology-Lung Cellular and Molecular Physiology, 301, L125.

Murine Lung

Ogawa,H., Azuma,M., Muto,S., Nishioka,Y., Honjo,A., Tezuka,T., Uehara,H., Izumi,K., Itai,A. and Sone,S. (2011)

Iκβ-kinase β inhibitor IMD0354 suppresses airway remodelling in a Dermatophagoides

pteronyssinussensitized mouse model of chronic asthma. Clinical & Experimental Allergy, 41, 104-115.

Human Fibroblasts

Oh,E.J., Kim,T.K., Shin,J.H., Choi,J.H. and Chung,H.Y. (2011) Biologic Filler Using Human Fibroblasts and Placenta Extracts. Journal of Craniofacial Surgery, 22, 1557.

Murine Lung Tissue

Oh,K., Park,H.B., Byoun,O.J., Shin,D.M., Jeong,E.M., Kim,Y.W., Kim,Y.S., Melino,G., Kim,I.G. and Lee,D.S. (2011) Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice. The Journal of Experimental Medicine 208,1707.

Human Fibroblasts

Ogawa,T., Imaizumi,K., Hashimoto,N., Hashimoto,I., Imai,N., Tomita,Y., Kounou,T., Sakamoto,K., Aoyama,D. and Kusunose,M. (2011) The Role Of Interleukin-17/Th17 In Human Interstitial Pneumonia. American Journal of Respiratory and Critical Care Medicine, 183, A4282.

Human Skin Samples

Oh,M.H., Oh,S.Y., Yu,J., Myers,A.C., Leonard,W.J., Liu,Y.J., Zhu,Z. and Zheng,T. (2011) IL-13 Induces Skin Fibrosis in Atopic Dermatitis by Thymic Stromal Lymphopoietin. The Journal of Immunology, 186, 7232.

Murine Skin Tissue

Olaso,E., Lin,H.C., Wang,L.H. and Friedman,S.L. (2011) Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling. Fibrogenesis & Tissue Repair, 4, 5.

Hamster Peritoneal Macrophages

Osorio,Y., Travi,B.L., Renslo,A.R., Peniche,A.G., Melby,P.C. and Geary,T.G. (2011) Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System. PLoS Neglected Tropical Diseases, 5, 111-126.

Murine Colonic Tissue

Oz,H.S., Zhong,J. and de Villiers,W.J.S. (2011) Osteopontin Ablation Attenuates Progression of Colitis in TNBS Model. Digestive Diseases and Sciences, doi: 10.1007/s10620-011-2009-z.

Murine Colonic Tissue

Oz,H.S., Zhong,J. and de Villiers,W.J.S. (2011) Osteopontin Ablation Attenuates Progression of Colitis in TNBS Model. Digestive Diseases and Sciences, doi: 10.1007/s10620-011-2009-z.

Collagen Type I Isolated from Rabbit, Lamb and Human Skin

Pacak,C.A., Powers,J.M. and Cowan,D.B. (2011) Ultrarapid Purification of Collagen Type I for Tissue Engineering Applications. Tissue Engineering Part C: Methods, 17, 879 – 885.

Rat Hepatic Stellate Cells HSC-T6

Pan,T.L., Wang,P.W., Leu,Y.L., Wu,T.H. and Wu,T.S. (2011) Inhibitory effects of Scutellaria baicalensis extract on hepatic stellate cells through inducing G2/M cell cycle arrest and activating ERK-dependent apoptosis via Bax and caspase pathway. Journal of Ethnopharmacology, http://dx.doi.org/10.1016/j.jep.2011.12.028.

Nasal Polyp-Derived Fibroblasts

Park,I.H., Choi,H., Lee,H.M. and Kim,Y.D. (2011) Effect of Berberine on Nasal Polyp-derived Fibroblast. Otolaryngology--Head and Neck Surgery, 145, 119.

Rat Lung Tissue

Pauluhn,J. and Wiemann,M. (2011) Siderite (FeCO3) and magnetite (Fe3O4) overload-dependent pulmonary toxicity is determined by the poorly soluble particle not the iron content. Inhalation Toxicology, 23, 763-783.

Murine Fibrosarcoma L929 Fibroblasts and Primary Lung Fibroblasts

Pfau,J.C., Li,S., Holland,S. and Sentissi,J.J. (2011) Alteration of fibroblast phenotype by asbestos-induced autoantibodies. Journal of Immunotoxicology, 8, 159 – 169.

Murine Bronchoalveolar Lavage Fluid

Pedroza,M., Schneider,D.J., Karmouty-Quintana,H., Coote,J., Shaw,S., Corrigan,R., Molina,J.G., Alcorn,J.L., Galas,D. and Gelinas,R. (2011) Interleukin-6 Contributes to Inflammation and Remodeling in a Model of Adenosine Mediated Lung Injury. PloS one, 6, e22667.

Murine Lung Tissue

Peng,X., Mathai,S.K., Murray,L.A., Russell,T., Reilkoff,R., Chen,Q., Gulati,M., Elias,J.A., Bucala,R. and Gan,Y. (2011) Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis. Fibrogenesis & Tissue Repair, 4, 12.

L929 Fibroblasts and Primary Lung Fibroblasts

Pfau,J.C., Li,S., Holland,S. and Sentissi,J.J. (2011) Alteration of fibroblast phenotype by asbestos-induced autoantibodies. Journal of Immunotoxicology, 8, 159 - 169.

Primary Human Tenocytes

Poulsen,R.C., Carr,A.J. and Hulley,P.A. (2011) Protection against Glucocorticoid-Induced Damage in Human Tenocytes by Modulation of ERK, Akt, and Forkhead Signaling. Endocrinology, 152, 503.

Accellularised Human Flexor Tendons

Pridgen,B.C., Woon,C.Y.L., Kim,M., Thorfinn,J., Lindsey,D., Pham,H. and Chang,J. (2011) Flexor Tendon Tissue Engineering: Acellularization of Human Flexor Tendons with Preservation of Biomechanical Properties and Biocompatibility. Tissue Engineering Part C: Methods, 17, 819 – 828.

Murine Lung Tissue

Przybyszewska,M., Miłoszewska,J., Rzońca,S., Trembacz,H., Pyśniak,K., Kotlarz,A., Swoboda,P., Zalewska,M. and Małecki,M. (2011) Soluble TNF-α Receptor I Encoded on Plasmid Vector and Its Application in Experimental Gene Therapy of Radiation-Induced Lung Fibrosis. Archivum immunologiae et therapiae experimentalis, 59, 315 - 326.

Murine Lung Tissue

Rabolli,V., Re,S.L., Uwambayinema,F., Yakoub,Y., Lison,D. and Huaux,F. (2011) Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice. Toxicology Letters, 203, 127 – 134.

Dog Articular Chondrocytes

Rai,M.F., Graeve,T., Twardziok,S. and Schmidt,M.F.G. (2011) Evidence for Regulated Interleukin-4 Expression in Chondrocyte-Scaffolds under In Vitro Inflammatory Conditions. PloS one, 6, e25749.

Murine Lung

Ravichandran,P., Baluchamy,S., Gopikrishnan,R., Biradar,S., Ramesh,V., Goornavar,V., Thomas,R., Wilson,B.L., Jeffers,R. and Hall,J.C. (2011) Pulmonary Biocompatibility Assessment of Inhaled Single-wall and Multiwall Carbon Nanotubes in BALB/c Mice. Journal of Biological Chemistry, 286, 29725-29733.

Murine Colon

Reardon,C., Lechmann,M., Brüstle,A., Gareau,M.G., Shuman,N., Philpott,D., Ziegler,S.F. and Mak,T.W. (2011) Thymic Stromal Lymphopoetin-Induced Expression of the Endogenous Inhibitory Enzyme SLPI Mediates Recovery from Colonic Inflammation. Immunity, 35, 223 – 235.

Human Mesenchymal Cells

Re’em,T., Kaminer-Israeli,Y., Ruvinov,E. and Cohen,S. (2011) Chondrogenesis of hMSC in affinity-bound TGF-beta scaffolds. Biomaterials 33, 751 – 761.

Murine Lung Tissue

Reilkoff,R., Russell,T., Peng,X., Gulati,M., Homer,R., Elias,J.A. and Herzog,E. (2011) Semaphorin 7A Expression On Lymphocytes Promotes Alternative Macrophage Activation In Murine Models Of Lung Fibrosis And Human IPF. American Journal of Respiratory and Critical Care Medicine, 183, A5575.

Murine Lung Tissue

Reinke,C., Bevans-Fonti,S., Grigoryev,D.N., Drager,L.F., Myers,A.C., Wise,R.A., Schwartz,A.R., Mitzner,W. and Polotsky,V.Y. (2011) Chronic intermittent hypoxia induces lung growth in adult mice. American Journal of Physiology-Lung Cellular and Molecular Physiology, 300, L266.

Rat Aorta

Roan,J.N., Tsai,Y.C., Chen,I.W., Chang,S.W., Huang,C.C. and Lam,C.F. (2011) Inhibition of cyclooxygenase-2 modulates phenotypic switching of vascular smooth muscle cells during increased aortic blood flow. Heart and Vessels, doi: 10.1007/s00380-011-0148-y.

Murine Lung Tissue

Russo,R.C., Garcia,C.C., Barcelos,L.S., Rachid,M.A., Guabiraba,R., RoffE., Souza,A.L.S., Sousa,L.P., Mirolo,M. and Doni,A. (2011) Phosphoinositide 3-kinase plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice. Journal of Leukocyte Biology, 89, 269.

Human Dermal Fibroblasts

Saito,S., Takayama,Y., Mizumachi,K. and Suzuki,C. (2011) Lactoferrin promotes hyaluronan synthesis in human dermal fibroblasts. Biotechnology letters, 33, 33 – 39.

Coprothermobacter proteolyticus and Methanothermobacter thermautotrophicus

Sasaki,K., Morita,M., Sasaki,D., Nagaoka,J., Matsumoto,N., Ohmura,N. and Shinozaki,H. (2011) Syntrophic degradation of proteinaceous materials by the thermophilic strains Coprothermobacter proteolyticus and Methanothermobacter thermautotrophicus. Journal of Bioscience and Bioengineering 112, 469 – 472.

Murine Lung Tissue

Satish,K. (2011) Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice. Pulmonary Medicine, doi: 10.1155/2011/653524.

Co-Culture of Fibrocytes with Airway Smooth Muscle

Saunders,R., Kaur,D., Doe,C., Siddiqui,S., Wardlaw,A., Bradding,P. and Brightling,C.E. (2011) Co-Culture Of Fibrocytes With Airway Smooth Muscle Effects Fibrocyte Phenotype And Composition Of The Extracellular Milieu. American Journal of Respiratory and Critical Care Medicine, 183, A4055.

Rat HSC-T6 Hepatic Stellate Cells

Shin,E., Lee,C., Sung,S.H., Kim,Y.C., Hwang,B.Y. and Lee,M.K. (2011) Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells. Journal of Natural Medicines, 65, 370 - 374.

Different Cell Lines

Shona Pek,Y. and Wan,A.C.A. (2011) Characterization of early extracellular matrix secretions in a three-dimensional thixotropic cell culture system. Acta Biomaterialia 7, 3981 – 3987.

Human Periodontal Ligament Stem Cells

Song,D., Park,J., Jung,I., Choi,S., Cho,K. and Kim,C. (2011) Enhanced adipogenic differentiation and reduced collagen synthesis induced by human periodontal ligament stem cells might underlie the negative effect of

recombinant human bone morphogenetic protein2 on periodontal regeneration. Journal of periodontal research 46, 193 – 203.

Murine Lung Tissue

Sugino,K., Ito,T., Muramatsu,Y., Tatebe,J., Morita,T., Matsuda,K., Azuma,A. and Homma,S. (2011) N-Acetylcysteine And Pirfenidone Attenuate Expression Of Epithelial Mesenchymal Transition In Murine Bleomycin-Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 183, A4288.

Murine Kidney

Sugiyama,N., Kohno,M. and Yokoyama,T. (2011) Inhibition of the p38 MAPK pathway ameliorates renal fibrosis in an NPHP2 mouse model. Nephrology Dialysis Transplantation doi: 10.1093/ndt/gfr550.

Rodent Models of Lung and Kidney Fibrosis and Wound Healing

Swaney,J.S., Chapman,C., Correa,L.D., Stebbins,K.J., Broadhead,A.R., Bain,G., Santini,A.M., Darlington,J., King,C.D. and Baccei,C.S. (2011) Pharmacokinetic and Pharmacodynamic Characterization of an Oral Lysophosphatidic Acid Type 1 Receptor-Selective Antagonist. Journal of Pharmacology and Experimental Therapeutics, 336, 693.

Human MG63 Osteosarcoma Cells

Tan,F., Naciri,M. and AlRubeai,M. (2011) Osteoconductivity and growth factor production by MG63 osteoblastic

cells on bioglasscoated orthopedic implants. Biotechnology and Bioengineering 108, 454 – 464.

Murine Lung Tissue

Teeguarden,J.G., Webb-Robertson,B.J., Waters,K.M., Murray,A.R., Kisin,E.R., Varnum,S.M., Jacobs,J.M., Pounds,J.G., Zanger,R.C. and Shvedova,A.A. (2011) Comparative Proteomics and Pulmonary Toxicity of Instilled Single-Walled Carbon Nanotubes, Crocidolite Asbestos, and Ultrafine Carbon Black in Mice. Toxicological Sciences, 120, 123 – 135.

Mesenchymal Stem Cells

Teh,T.K.H., Toh,S.L. and Goh,J.C.H. (2011) Aligned Hybrid Silk Scaffold for Enhanced Differentiation of Mesenchymal Stem Cells into Ligament Fibroblasts. Tissue Engineering Part C: Methods, 17, 687 – 703.

Human Adipose Stem Cells

Tirkkonen,L., Halonen,H., Hyttinen,J., Kuokkanen,H., Sievänen,H., Koivisto,A.M., Mannerström,B., Sándor,G.K.B., Suuronen,R. and Miettinen,S. (2011) The effects of vibration loading on adipose stem cell number, viability and differentiation towards bone-forming cells. Journal of The Royal Society Interface, 8, 1736-1747.

Porcine Chondrocytes

Tran,S.C., Cooley,A.J. and Elder,S.H. (2011) Effect of a mechanical stimulation bioreactor on tissue engineered,

scaffoldfree cartilage. Biotechnology and Bioengineering 108, 1421 – 1429.

Osteoblast Cell Cultures

Tulyaganov,D., Agathopoulos,S., Valerio,P., Balamurugan,A., Saranti,A., Karakassides,M. and Ferreira,J. (2011) Synthesis, bioactivity and preliminary biocompatibility studies of glasses in the system CaO-MgO-SiO2-Na2O-P2O5-CaF2. Journal of Materials Science: Materials in Medicine, 22, 217-227.

Murine Colonic Tissue

Turner,J.D., Jenkins,G.R., Hogg,K.G., Aynsley,S.A., Paveley,R.A., Cook,P.C., Coles,M.C. and Mountford,A.P. (2011) CD4+ CD25+ Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection. PLoS Neglected Tropical Diseases, 5, e1269.

Primary Mesangial Cells, Parietal Epithelial Cells and Macrophages

Urushihara,M., Ohashi,N., Miyata,K., Satou,R., Acres,O.W. and Kobori,H. (2011) Addition of Angiotensin II Type 1 Receptor Blocker to CCR2 Antagonist Markedly Attenuates Crescentic Glomerulonephritis. Hypertension, 57, 586-593.

Porcine Anterior Cruciate Ligament Fibroblasts

Vavken,P., Joshi,S.M. and Murray,M.M. (2011) Fibrin concentration affects ACL fibroblast proliferation and collagen synthesis. The Knee, 18, 42-46.

Primary Human Tenocytes

Vetrano,M., d’Alessandro,F., Torrisi,M.R., Ferretti,A., Vulpiani,M.C. and Visco,V. (2011) Extracorporeal shock wave therapy promotes cell proliferation and collagen synthesis of primary cultured human tenocytes. Knee Surgery, Sports Traumatology, Arthroscopy, 19, 2159 – 2168.

Murine Lung Tissue

Wang,X., Katwa,P., Podila,R., Chen,P., Ke,P.C., Rao,A.M., Walters,D.M., Wingard,C.J. and Brown,J.M. (2011) Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice. Particle and fibre toxicology, 8, 24.

Murine Lung Tissue

Wang,X., Xia,T., Ntim,S.A., Ji,Z., Lin,S., Meng,H., Chung,C.H., George,S., Zhang,H. and Wang,M. (2011) The Dispersal State of Multi-walled Carbon Nanotubes Elicits Pro-Fibrogenic Cellular Responses that Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung. ACS Nano 5, 9772 – 9787.

Horse Mid-Metacarpal Superficial Digital Flexor Tendon

Watts,A.E., Nixon,A.J., Yeager,A.E. and Mohammed,H.O. (2011) A collagenase gel/physical defect model for controlled induction of superficial digital flexor tendonitis. Equine Veterinary Journal, doi: 10.1111/j.2042-3306-2011.00471.x.

Male, Fetal Derived Embryonic-Like Stem Cells

Watts,A.E., Yeager,A.E., Kopyov,O.V. and Nixon,A.J. (2011) Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model. Stem Cell Research & Therapy, 2, 4.

Murine Skin Tissue and Murine Skin Fibroblasts

Wei,J., Melichian,D., Komura,K., Hinchcliff,M., Lam,A.P., Lafyatis,R., Gottardi,C.J., MacDougald,O.A. and Varga,J. (2011) Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma? Arthritis & Rheumatism, 63, 1707 – 1717.

Rat Hepatic Stellate Cells (HSC-T6)

Weng,T.C., Shen,C.C., Chiu,Y.T., Lin,Y.L. and Huang,Y.T. (2011) Effects of Armepavine Against Hepatic Fibrosis Induced by Thioacetamide in Rats. Phytotherapy Research doi: 10.1002/ptr.3539.

Human Smooth Muscle and Mesenchymal Stem Cells

Williams,C., Xie,A., Emani,S., Yamato,M., Okano,T., Emani,S.M. and Wong,J. (2011) A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue engineered vascular patches. Tissue Engineering doi: 10.1089/ten.TEA.2011.0172.

Human Fibroblasts

Wong,V.W., Rustad,K.C., Akaishi,S., Sorkin,M., Glotzbach,J.P., Januszyk,M., Nelson,E.R., Levi,K., Paterno,J. and Vial,I.N. (2011) Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling. Nature Medicine doi: 10.1038/nm.2574.

Fibroblasts

Woon,C.Y.L., Pridgen,B.C., Kraus,A., Bari,S., Pham,H. and Chang,J. (2011) Optimization of Human Tendon Tissue Engineering: Peracetic Acid Oxidation for Enhanced Reseeding of Acellularized Intrasynovial Tendon. Plastic and Reconstructive Surgery, 127, 1107.

Bone Marrow Mesenchymal Mononuclear Cells

Wu,W., Allen,R., Gao,J. and Wang,Y. (2011) Artificial Niche Combining Elastomeric Substrate and Platelets Guides Vascular Differentiation of Bone Marrow Mononuclear Cells. Tissue Engineering Part A, 17, 1979 – 1992.

Macrophages and Whole Tissues

Wynn,T.A., Barron,L., Thompson,R.W., Madala,S.K., Wilson,M.S., Cheever,A.W. and Ramalingam,T. (2011) Quantitative Assessment of Macrophage Functions in Repair and Fibrosis. Current Protocols in Immunology, Current Protocols in Immunology, 14, 1-14.

Osteoblastic MC3T3-E1 Cells

Xu,Z.S., Wang,X.Y., Xiao,D.M., Hu,L.F., Lu,M., Wu,Z.Y. and Bian,J.S. (2011) Hydrogen sulfide protects MC3T3-E1 osteoblastic cells against H2O2-induced oxidative damage-Implication for treatment of osteoporosis. Free Radical Biology and Medicine, 50, 1314 – 1323.

Murine Monocyte/Macrophage Cell Line (RAW264.7)

Yahyouche,A., Zhidao,X. and Czernuszka,J. (2011) Macrophage-Mediated Degradation of Crosslinked Collagen Scaffolds. Acta Biomaterialia, 7, 278 – 286.

Murine Lung Tissue

Yamauchi,K., Kasuya,Y., Kuroda,F., Tanaka,K., Tsuyusaki,J., Ishizaki,S., Matsunaga,H., Iwamura,C., Nakayama,T. and Tatsumi,K. (2011) Attenuation of lung inflammation and fibrosis in CD69-deficient mice after intratracheal bleomycin. Respiratory Research, 12, 131.

Murine Lung Tissue

Yang,S., Banerjee,S., de Freitas,A., Sanders,Y.Y., Ding,Q., Matalon,S., Thannickal,V.J., Abraham,E. and Liu,G. (2011) Participation of miR-200 in Pulmonary Fibrosis. The American Journal of Pathology doi: org/10.1016/j.ajpath.2011.10.005.

Murine Lung Tissue

Young,S.K., Campbell,M., Briones,N., Yamashita,C., Downey,G.P. and Khalifah,A.P. (2011) Protein Tyrosine Phosphatase- ±Deficiency In Mice Protects Against Bleomycin-Induced Lung Fibrosis And Causes Aberrant Response To TGF2. Am J Respir Crit Care Med, 183, A6431.

Murine Lung Tissue

Yu,M., Eckart,M.R., Morgan,A.A., Mukai,K., Butte,A.J., Tsai,M. and Galli,S.J. (2011) Identification of an IFN- /mast cell axis in a mouse model of chronic asthma. J Clin Invest., 121, 3133 – 3143.

Human Fibroblasts

Yun,J.S., Pahk,J.W., Lee,J.S., Shin,W.C., Lee,S.Y. and Hong,E.K. (2011) Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence. Molecules and Cells, 31, 423 – 429.

Human Mesenchymal Stem Cells

Zhang,B., Yang,S., Sun,Z., Zhang,Y., Xia,T., Xu,W. and Ye,S. (2011) Human Mesenchymal Stem Cells Induced by Growth Differentiation Factor 5: An Improved Self-Assembly Tissue Engineering Method for Cartilage Repair. Tissue Engineering Part C: Methods 17, 1189 – 1199.

Rat Proximal Tubule Cell Line

Zhang,D., Yang,H., Kong,X., Wang,K., Mao,X., Yan,X., Wang,Y., Liu,S., Zhang,X. and Li,J. (2011) Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. American Journal of Physiology-Endocrinology And Metabolism, 300, E287.

Rat Ventricular Fibroblasts

Zhang,P., Su,J., King,M.E., Maldonado,A.E., Park,C. and Mende,U. (2011) Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses. American Journal of Physiology-Heart and Circulatory Physiology, 301, H147.

Rat Fibroblasts

Zhang,Q., O'Hearn,S., Kavalukas,S.L. and Barbul,A. (2011) Role of High Mobility Group Box 1 (HMGB1) in Wound Healing. Journal of Surgical Research, doi: 10.1016/j.jss.2011.06.069.

Primary Human Cardiac Fibroblasts

Zhong,H., Belardinelli,L. and Zeng,D. (2011) Pro-Fibrotic Role of the A2B Adenosine Receptor in Human Cardiac Fibroblasts. Journal of Cardiac Failure, 17, S65.

Human Vocal Fold Fibroblasts

Zhou,H., Felsen,D., Sandulache,V.C., Amin,M.R., Kraus,D.H. and Branski,R.C. (2011) Prostaglandin (PG) E2 exhibits antifibrotic activity in vocal fold fibroblasts. The Laryngoscope, doi: 10.1002/lary.21795.

Human Vocal Fold Fibroblasts

Zhou,H., Sivasankar,M., Kraus,D.H., Sandulache,V.C., Amin,M. and Branski,R.C. Glucocorticoids regulate extracellular matrix metabolism in human vocal fold fibroblasts. The Laryngoscope 121, 1915 – 1919.

Murine Lung Tissue

Zhou,Y., Schneider,D.J., Morschl,E., Song,L., Pedroza,M., Karmouty-Quintana,H., Le,T., Sun,C.X. and Blackburn,M.R. (2011) Distinct Roles for the A2B Adenosine Receptor in Acute and Chronic Stages of Bleomycin-Induced Lung Injury. The Journal of Immunology, 186, 1097.

2010

Murine Lung Tissue Ahmad,T., Mabalirajan,U., Hasija,K., Ghosh,B. and Agrawal,A. (2010) Mepacrine treatment attenuates allergic

airway remodeling segregated from airway inflammation in mice. International Immunopharmacology, doi: 10.1016/j.intimp.2010.10.008.

Murine MC3T3-E1 Pre-Osteoblasts

Alford,A.I., Terkhorn,S.P., Reddy,A.B. and Hankenson,K.D. (2010) Thrombospondin-2 regulates matrix mineralization in MC3T3-E1 pre-osteoblasts. Bone, 46, 464-471.

Murine Fibroblast Cell Line L929

Aramwit,P., Kanokpanont,S., Nakpheng,T. and Srichana,T. (2010) The Effect of Sericin from Various Extraction Methods on Cell Viability and Collagen Production. Int. J. Mol. Sci. 11, 2200 – 2211.

Bovine Muscle Tissue

Archile-Contreras,A.C. and Purslow,P.P. (2010) Oxidative stress may affect meat quality by interfering with collagen turnover by muscle fibroblasts. Food Research International, doi: 10.1016/j.foodres.2010.12.002.

Rat Kidney Tissue

Asanuma,H., Vanderbrink,B.A., Campbell,M.T., Hile,K.L., Zhang,H., Meldrum,D.R. and Meldrum,K.K. (2010) Arterially Delivered Mesenchymal Stem Cells Prevent Obstruction-Induced Renal Fibrosis. Journal of Surgical Research, doi: 10.1016/j.jss.2010.06.022.

Mammalian Articular Cartilage

Bae,J.Y., Han,D.W., Matsumura,K., Wakitani,S., Nawata,M. and Hyon,S.H. (2010) Nonfrozen Preservation of Articular Cartilage by Epigallocatechin-3-Gallate Reversibly Regulating Cell Cycle and NF- κB Expression. Tissue Engineering Part A, 16, 595.

Murine Lung Dendritic Cells

Bantsimba-Malanda,C., Marchal-Somme,J., Goven,D., Freynet,O., Michel,L., Crestani,B. and Soler,P. (2010) A Role for Dendritic Cells in Bleomycin-induced Pulmonary Fibrosis in Mice? American Journal of Respiratory and Critical Care Medicine, 182, 385 - 395.

Human Fibroblasts

Bendersky,A., Markovits,N. and Bank,I. (2010) V γ9+γδT cells in systemic sclerosis patients are numerically and functionally preserved and induce fibroblast apoptosis. Immunobiology, 215, 380-394.

Human Skin Samples

Boisnic,S. and Branchet,M.C. (2010) Ex vivo study of the home-use TriPollar RF device using an experimental human skin model. Journal of Dermatological Treatment, 21, 301 - 335.

Human Gingival Tissue

Boisnic,S., Ben Slama,L. and Branchet-Gumila,M.C. (2010) Comparaison de l'effet anti-inflammatoire et rparateur

de deux dentifrices sur un mod le exprimental de muqueuse gingivale humaine. Revue de Stomatologie et de Chirurgie Maxillo-faciale, 111, 291 – 295.

Murine Lung Tissue

Busse,P.J., Schofield,B., Birmingham,N., Yang,N., Wen,M.C., Zhang,T.F., Srivastava,K. and Li,X.M. (2010) The traditional Chinese herbal formula ASHMI inhibits allergic lung inflammation in antigen-sensitized and antigen-challenged aged mice. Annals of Allergy, Asthma & Immunology, 104, 236-246.

Rat Lung Tissue

Calveley,V.L., Jelveh,S., Langan,A., Mahmood,J., Yeung,I.W.T., Van Dyk,J. and Hill,R.P. (2010) Genistein Can Mitigate the Effect of Radiation on Rat Lung Tissue. Radiation Research, 173, 602-611.

Rat Hepatic Stellate Cells

Cao,S., Yaqoob,U., Das,A., Shergill,U., Jagavelu,K., Huebert,R.C., Routray,C., Abdelmoneim,S., Vasdev,M. and

Leof,E. (2010) Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF- β

signaling in hepatic stellate cells. J Clin Invest. 120, 2379–2394.

Murine Dorsal Tissue

Chang,P.J., Chen,M.Y., Huang,Y.S., Lee,C.H., Huang,C.C., Lam,C.F. and Tsai,Y.C. (2010) Morphine enhances tissue content of collagen and increases wound tensile strength. Journal of Anesthesia, 24, 240-246.

Hepatic Stellate Cells (HSC-T6)

Chen,B.Y., Qu,P., Tie,R., Zhu,M.Z., Zhu,X.X. and Yu,J. (2010) Protecting effects of vasonatrin peptide against carbon tetrachloride-induced liver fibrosis. Regulatory Peptides, 164, 139 – 143.

Mesenchymal Stem Cells

Cheng,H., Luk,K.D.K., Cheung,K. and Chan,B.P. (2010) In vitro generation of an osteochondral interface from mesenchymal stem cell-collagen microspheres. Biomaterials, 32, 1526 – 1535.

Murine Aorta

Cheng,S.L., Shao,J.S., Halstead,L.R., Distelhorst,K., Sierra,O. and Towler,D.A. (2010) Activation of Vascular Smooth Muscle Parathyroid Hormone Receptor Inhibits Wnt/β-Catenin Signaling and Aortic Fibrosis in Diabetic Arteriosclerosis. Circulation research, 107, 271 – 282.

Fibroblasts

Chiang,H.M., Lin,T.J., Chiu,C.Y., Chang,C.W., Hsu,K.C., Fan,P.C. and Wen,K.C. (2010) Coffea arabica extract and its constituents prevent photoaging by suppressing MMPs expression and MAPK pathway. Food and Chemical Toxicology, 49, 309 – 318.

Human Fibroblasts

Choi,H., Kim,D., Kim,J.W., Ngadiran,S., Sarmidi,M.R. and Park,C.S. (2010) Labisia pumila extract protects skin cells from photoaging caused by UVB irradiation. Journal of Bioscience and Bioengineering, 109, 291-296.

Rat Liver Tissue

Choi,J.H., Hwang,Y.P., Choi,C.Y., Chung,Y.C. and Jeong,H.G. (2010) Anti-fibrotic effects of the anthocyanins isolated from the purple-fleshed sweet potato on hepatic fibrosis induced by dimethylnitrosamine administration in rats. Food and Chemical Toxicology, 48, 3137 - 3143.

Human Tenon's Fibroblasts

Choritz,L., Grub,J., Wegner,M., Pfeiffer,N. and Thieme,H. (2010) Paclitaxel inhibits growth, migration and collagen production of human Tenon's fibroblastsùpotential use in drug-eluting glaucoma drainage devices. Graefe's Archive for Clinical and Experimental Ophthalmology, 248, 197-206.

Bovine Thoracic Aortic Tissue

Chow,M.J. and Zhang,Y. (2010) The Change in Mechanical and Biochemical Properties of Aortic Tissue Due to Cold Storage. Journal of Surgical Research, doi:10.1016/j.jss.2010.04.007.

Fetal Cardiac Fibroblasts

Clancy,R.M., Alvarez,D., Komissarova,E., Barrat,F.J., Swartz,J. and Buyon,J.P. (2010) Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block. The Journal of Immunology, 184, 2148.

Murine Lung Tissue

Cowden,J.M., Riley,J.P., Ma,J.Y., Thurmond,R.L. and Dunford,P.J. (2010) Histamine H 4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th 2 cytokines. Respiratory Research, 11, 86.

Murine Tail Tissue

Damodarasamy,M., Vernon,R.B., Karres,N., Chang,C.H., Bianchi-Frias,D., Nelson,P.S. and Reed,M.J. (2010) Collagen Extracts Derived from Young and Aged Mice Demonstrate Different Structural Properties and Cellular Effects in Three-Dimensional Gels. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Series A, 65, 209 - 218.

Rat Bone Marrow Mesenchymal Stem Cells

de Melo Ocarino,N., Boeloni,J.N., Jorgetti,V., Gomes,D.A., Goes,A.M. and Serakides,R. (2010) Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats. Connective Tissue Research, 51, 426 - 433.

Murine Model of Scleroderma

Derrett-Smith,E., Dooley,A., Khan,K., Shi-wen,X., Abraham,D. and Denton,C. (2010) Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma. Arthritis Research & Therapy, 12, R69.

Human Oral Submucosal Tissue

Dhariwal,R. and Mukherjee,S. (2010) Zinc and vitamin A can minimise the severity of oral submucous fibrosis. (2010) BMJ Case Reports, doi:10.1136/bcr.10.2009.2348.

Rat Neonatal Calvarial Osteoblasts

Dias,R.C.M., Góes,A.M., Serakides,R., Ayres,E. and Oréfice,R.L. (2010) Porous biodegradable polyurethane nanocomposites: preparation, characterization, and biocompatibility tests. Materials Research, 13, 211-218.

Lung Fibroblast Cells

Du,X., Jiang,S., Liu,H., Xin,X., Li,J., Geng,M. and Jiang,H. (2010) MS80, a novel sulfated polysaccharide, inhibits CD40-NF- B pathway via targeting RIP2. Molecular and Cellular Biochemistry, 337, 277-285.

Human Dermal Tissue

Eberli,D., Rodriguez,S., Atala,A. and Yoo,J.J. (2010) In vivo evaluation of acellular human dermis for abdominal wall repair. Journal of Biomedical Materials Research Part A, 93, 1527-1538.

Murine Lung Tissue

Ekstrand-Hammarström,B., Wigenstam,E. and Bucht,A. (2010) Inhalation of alkylating mustard causes long-term T cell-dependent inflammation in airways and growth of connective tissue. Toxicology, doi: 10.1016/j.tox.2010.11.012.

Murine Retinal Pigment Epithelial Cells

Elliot,S.J., Catanuto,P., Espinosa-Heidmann,D.G., Fernandez,P., Hernandez,E., Saloupis,P., Korach,K., Karl,M. and Cousins,S.W. (2010) Estrogen receptor β protects against in vivo injury in RPE cells. Experimental eye research, 90, 10-16.

Human Anterior Cruciate Ligament (ACL) Cells

Fallouh,L., Nakagawa,K., Sasho,T., Arai,M., Kitahara,S., Wada,Y., Moriya,H. and Takahashi,K. (2010) Effects of Autologous Platelet-Rich Plasma on Cell Viability and Collagen Synthesis in Injured Human Anterior Cruciate Ligament. The Journal of Bone and Joint Surgery, 92, 2909 – 2916.

Bronchial Epithelial Cell Line RL-65

Felton,V.M., Inge,L.J., Willis,B.C., Bremner,R.M. and Smith,M.A. (2010) Immunosuppression-induced bronchial epithelial-mesenchymal transition: A potential contributor to obliterative bronchiolitis. The Journal of Thoracic and Cardiovascular Surgery, doi: 10.1016/j.jtcvs.2010.10.006.

Murine Lung Tissue

Fukumoto,J., Harada,C., Kawaguchi,T., Suetsugu,S., Maeyama,T., Inoshima,I., Hamada,N., Kuwano,K. and Nakanishi,Y. (2010) Amphiregulin attenuates bleomycin-induced pneumopathy in mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, 298, L131 – L138.

Fibrocytes

Garcia-de-Alba,C., Becerril,C., Ruiz,V., Gonzalez,Y., Reyes,S., Garcia-Alvarez,J., Selman,M. and Pardo,A. (2010) Expression of Matrix Metalloproteases by Fibrocytes. Possible Role in Migration and Homing. American Journal of Respiratory and Critical Care Medicine,182, 1144 –1152.

Murine Lung Tissue

García-Prieto,E., González-López,A., Cabrera,S., Astudillo,A., Gutiérrez-Fernández,A., Fanjul-Fernandez,M., Batalla-Solís,E., Puente,X.S., Fueyo,A. and López-Otín,C. (2010) Resistance to Bleomycin-Induced Lung Fibrosis in MMP-8 Deficient Mice Is Mediated by Interleukin-10. PloS one, 5, 835-839.

Lung Tissue

Garibaldi,B.T., D'Alessio,F.R., Files,D.C., Chau,E., Sidhaye,V., Fraig,M. and King,L.S. (2010) Regulatory T-lymphocytes Play A Key Role In The Fibroproliferative Response To Acute Lung Injury. American Journal of Respiratory and Critical Care Medicine, 181, A3772.

Murine Lung Tissue

Gill,S.E., Huizar,I., Bench,E.M., Sussman,S.W., Wang,Y., Khokha,R. and Parks,W.C. (2010) Tissue Inhibitor of Metalloproteinases 3 Regulates Resolution of Inflammation following Acute Lung Injury. American Journal of Pathology, 176, 64.

Human Mesenchymal Stromal Cells from Adipose Tissue

Giusta,M.S., Andrade,H., Santos,A.V., Castanheira,P., Lamana,L., Pimenta,A.M.C. and Goes,A.M. (2010) Proteomic analysis of human mesenchymal stromal cells derived from adipose tissue undergoing osteoblast differentiation. Cytotherapy, 12, 478-490.

Murine Airway Epithelial Tissue

Gregory,L.G., Mathie,S.A., Walker,S.A., Pegorier,S., Jones,C.P. and Lloyd,C.M. (2010) Overexpression of SMAD2 Drives House Dust Mite- Mediated Airway Remodeling and Airway Hyperresponsiveness via Activin and Il-25. American Journal of Respiratory and Critical Care Medicine, 182, 143.

Lung Tissue

Hardie,W., LeCras,T., Korfhagen,T., Davidson,C., Schmidt,S., Ikegami,M. and Whitsett,J.A. (2010) Inhibition Of PI3K Reverses Transforming Growth Factor-alpha Induced Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 181, A1058.

Human Hepatic Stellate Cell Line (LX-2)

Hasegawa,D., Fujii,R., Yagishita,N., Matsumoto,N., Aratani,S., Izumi,T., Azakami,K., Nakazawa,M., Fujita,H. and Sato,T. (2010) E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis. PloS one, 5, 209-218.

Rat Model for Abdominal Wall Replacement

Hashizume,R., Fujimoto,K.L., Hong,Y., Amoroso,N.J., Tobita,K., Miki,T., Keller,B.B., Sacks,M.S. and Wagner,W.R. (2010) Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffold. Biomaterials, 31, 3253 – 3265.

Inner Annulus Fibrosus (AF) and Nucleus Pulposus (NP) Tissues

Hee,H.T., Zhang,J. and Wong,H.K. (2010) Effects of cyclic dynamic tensile strain on previously compressed inner annulus fibrosus and nucleus pulposus cells of human intervertebral disc-an in vitro study. Journal of Orthopaedic Research, 28, 503-509.

Human Inner Annulus Fibrosus (AF) and Nucleus Pulposus (NP) Cells.

Hee,H.T., Zhang,J. and Wong,H.K. (2010) An in vitro study of dynamic cyclic compressive stress on human inner

annulus fibrosus and nucleus pulposus cells. The Spine Journal, 10, 795 – 801.

Human Smooth Muscle Cells Derived From Neurogenic Bladders

Hodges,S.J., Yoo,J.J., Mishra,N. and Atala,A. (2010) The Effect of Epigenetic Therapy on Congenital Neurogenic Bladders - A Pilot Study. Urology, 75, 868 – 872.

Murine Colon, Liver and Lung Tissue

Hunter,M.M., Wang,A., Parhar,K.S., Johnston,M.J.G., van Rooijen,N., Beck,P.L. and McKay,D.M. (2010) In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice. Gastroenterology, 138, 1395-1405.

Rat Bone Marrow Stromal Cells (MSC) and MC3T3-E1 Cells

Ichinohe,N., Nakano,T., Mitaka,T., Umakoshi,Y. and Tabata,Y. (2010) Proliferation and osteogenic differentiation of rat bone marrow stromal cells on bioapatite with different crystalline facets. Journal of Biomedical Materials Research Part A, 93, 646-655.

Rat Achilles Tendon Fibroblasts

Irie,T., Takahata,M., Majima,T., Abe,Y., Komatsu,M., Iwasaki,N. and Minami,A. (2010) Effect of selective estrogen receptor modulator/raloxifene analogue on proliferation and collagen metabolism of tendon fibroblast. Connective Tissue Research, 51, 179-187.

Murine Achilles and Tail Tendons

Ito,Y., Toriuchi,N., Yoshitaka,T., Ueno-Kudoh,H., Sato,T., Yokoyama,S., Nishida,K., Akimoto,T., Takahashi,M. and Miyaki,S. (2010) The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proceedings of the National Academy of Sciences, 107, 10538.

Hepatocellular Carcinoma Cell Lines

Ji,J., Zhao,L., Budhu,A., Forgues,M., Jia,H.L., Qin,L.X., Ye,Q.H., Yu,J., Shi,X. and Tang,Z.Y. (2010) Let-7g targets collagen type I α2 and inhibits cell migration in hepatocellular carcinoma. Journal of Hepatology, 52, 690 - 697.

Primary Human Lung Fibroblasts

Jones,B., Bucks,C., Wilkinson,P., Pratta,M., Farrell,F. and Sivakumar,P. (2010) Development of Cell Based Immunoassays to Measure Type I Collagen in Cultured Fibroblasts. The International Journal of Biochemistry & Cell Biology, 42, 1808 – 1815.

Mesenchymal Stem Cells

Kalfa,D., Bel,A., Chen-Tournoux,A., la Martina,A., Rochereau,P., Coz,C., Bellamy,V., Bensalah,M., Vanneaux,V. and Lecourt,S. (2010) A polydioxanone electrospun valved patch to replace the right ventricular outflow tract in a growing lamb model. Biomaterials, 31, 4056 – 4063.

Rat Renal Cells

Kang,Y.S., Song,H.K., Lee,M.H., Ko,G.J., Han,J.Y., Han,S.Y., Han,K.H., Kim,H.K. and Cha,D.R. (2010) Visfatin is upregulated in type-2 diabetic rats and targets renal cells. Kidney International, 78, 170-181.

Murine Skin Tissue

Kanno,Y., Kawashita,E., Minamida,M., Kaneiwa,A., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2010) α2-Antiplasmin Is Associated with the Progression of Fibrosis. American Journal of Pathology, 176, 238.

Murine and Human Skin and Lung Tissue

Kavian,N., Servettaz,A., Mongaret,C., Wang,A., Nicco,C., Chéreau,C., Grange,P., Vuiblet,V., Birembaut,P. and Diebold,M.D. (2010) Targeting ADAM17-Notch signalling abrogates the development of systemic sclerosis in a murine model. Arthritis Rheum., 62, 3477 - 3487.

Murine Skin Tissue

Kawada,S., Ohtani,M. and Ishii,N. (2010) Increased oxygen tension attenuates acute ultraviolet-B-induced skin angiogenesis and wrinkle formation. American Journal of Physiology- Regulatory, Integrative and Comparative Physiology, 299, R694 – R701.

Murine Lung Tissue

Kearley,J., Erjefalt,J.S., Andersson,C., Benjamin,E., Jones,C.P., Robichaud,A., Pegorier,S., Brewah,Y., Burwell,T.J. and Bjermer,L. (2010) IL-9 Governs Allergen-induced Mast Cell Numbers in the Lung and Chronic Remodeling of the Airways. American Journal of Respiratory and Critical Care Medicine, doi: 10.1164/rccm.200909-1462OC.

Fibrocytes

Keeley,E.C., Mehrad,B. and Strieter,R.M. (2010) The Role of Fibrocytes in Lung Repair and Fibrosis. Stem Cells in the Respiratory System, doi:10.1007/978-1-60761-775-4_4.

Human Osteoarticular Cartilages and Chondrocytes

Kim,J.H., Huh,J.E., Baek,Y.H., Lee,J.D., Choi,D.Y. and Park,D.S. (2010) Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes. Journal of Ethnopharmacology, doi: 10.1016/j.jep.2010.12.005.

Murine Lung Tissue

Kim,J.S., Kim,D.Y., Lee,J.K., Ro,J.Y. and Chung,M.H. (2010) 8-oxo-2'-deoxyguanosine suppresses allergy-induced lung tissue remodeling in mice. European Journal of Pharmacology, 651, 218 – 226.

Murine Lung Tissue

Kim,T.H., Lee,Y.H., Kim,K.H., Lee,S.H., Cha,J.Y., Shin,E.K., Jung,S., Jang,A.S., Park,S.W. and Uh,S.T. (2010) Role of Lung Apolipoprotein A1 in Idiopathic Pulmonary Fibrosis: Anti-inflammatory and Anti-fibrotic Effect on Experimental Lung Injury/Fibrosis. American Journal of Respiratory and Critical Care Medicine, 182, 633 - 642.

Murine Embryonic Fibroblast Cell Line (NIH-3T3 Cells) and Primary Colonic Myofibroblasts

Kitamura,H., Yamamoto,S., Nakase,H., Matsuura,M., Honzawa,Y., Matsumura,K., Takeda,Y., Uza,N., Nagata,K. and Chiba,T. (2010) Role of Heat Shock Protein 47 in Intestinal Fibrosis of Experimental Colitis. Biochemical and Biophysical Research Communications, doi: 10.1016/j.bbrc.2010.12.006.

Fibroblast Cells

Klass,B.R., Branford,O.A., Grobbelaar,A.O. and Rolfe,K.J. (2010) The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor- ß1-stimulated wound contraction. Wound Repair and Regeneration, 18, 80-88.

Murine Lung Fibroblasts

Kohan,M., Muro,A.F., Bader,R. and Berkman,N. (2010) The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice. Journal of Allergy and Clinical Immunology, doi: 10.1016/j.jaci.2010.10.021.

Human Lung Fibroblasts

Kohan,M., Puxeddu,I., Reich,R., Levi-Schaffer,F. and Berkman,N. (2010) Eotaxin-2/CCL24 and eotaxin-3/CCL26 exert differential profibrogenic effects on human lung fibroblasts. Annals of Allergy, Asthma & Immunology, 104, 66-72.

Primary Lung Fibroblasts

Kohan,M., Muro,A.F., White,E.S. and Berkman,N. (2010) EDA-containing cellular fibronectin induces fibroblast differentiation through binding to α4 ß7 integrin receptor and MAPK/Erk 1/2-dependent signaling. The FASEB Journal, 24, 4503 - 4512.

Rat Lung Tissue

Kohno,M., Haramoto,M., Nakajima,O., Yang,L., Hinotsu,S., Yokohira,M., Imaida,K. and Kawakami,K. (2010) Antedrug Budesonide by Intrapulmonary Treatment Attenuates Bleomycin-Induced Lung Injury in Rats with Minimal Systemic Adverse Effects. Biological & Pharmaceutical Bulletin, 33, 1206-1211.

Murine Lung Tissue

Königshoff,M., Dumitrascu,R., Udalov,S., Amarie,O.V., Reiter,R., Grimminger,F., Seeger,W., Schermuly,R.T. and Eickelberg,O. (2010) Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax, doi:10.1136/thx.2009.134353.

Murine embryo Fibroblast Cell Line (NIH-3T3)

Kramer,M. (2010) The WNT/beta-catenin pathway: Profibrotic signaling in fibroblasts in Idiopathic Pulmonary Fibrosis. http://geb.uni-giessen.de/geb/volltexte/2010/7829.

Murine Lung Tissue

Krishnaveni,M., Li,C., Borok,Z., Minoo,P. and Li,M. (2010) Epithelial-Specific Deletion Of Transforming Growth Factor- (TGF- ) Receptor Type II (T RII) In The Lung Confers Relative Resistance To Bleomycin Injury. Am J Respir Crit Care Med, 181, A3525.

Murine Chondrocytic Cell Line

Kushibiki,T., Tajiri,T., Ninomiya,Y. and Awazu,K. (2010) Chondrogenic mRNA expression in prechondrogenic cells after blue laser irradiation. Journal of Photochemistry and Photobiology B: Biology, 98, 211 – 215.

Murine and Human Lung Fibroblasts (MRC-5)

Lang,Y.D., Chang,S.F., Wang,L.F. and Chen,C.M. (2010) Chymase mediates paraquat-induced collagen production in human lung fibroblasts. Toxicology letters, 193, 19-25.

Human Lung Fibroblasts

Lang,Y.D., Hung,C.L., Wu,T.Y., Wang,L.F. and Chen,C.M. (2010) The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts. Free Radical Biology and Medicine, 1,88-95.

Human Embryonic Lung Fibroblasts (WI-38 Cell Line) and Human Keloid Cadaveric Skin Tissues

Lareu,R.R., Zeugolis,D.I., bu-Rub,M., Pandit,A. and Raghunath,M. (2010) Essential modification of the Sircol Collagen Assay for the accurate quantification of collagen content in complex protein solutions. Acta biomaterialia, 6, 3146 – 3151.

Murine Brain Capillary Endothelial Cells

Lecht,S., rien-Zakay,H., Kohan,M., Lelkes,P.I. and Lazarovici,P. (2010) Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells. Molecular and Cellular Biochemistry, 339, 201-213.

Murine Lung Tissue

Le Cras,T.D., Korfhagen,T.R., Davidson,C., Schmidt,S., Fenchel,M., Ikegami,M., Whitsett,J.A. and Hardie,W.D. (2010) Inhibition of PI3K by PX-866 Prevents Transforming Growth Factor-α-Induced Pulmonary Fibrosis. American Journal of Pathology, 176, 679 - 686.

Ligament-Bone (LTB) Relevant Cells

Lee,J., Choi,W.I., Tae,G., Kim,Y.H., Kang,S.S., Kim,S.E., Kim,S.H., Jung,Y. and Kim,S.H. (2011) Enhanced regeneration of poly (L-lactide-co-ε-caprolactone) scaffold to ligament-to-bone interface by local delivery of cells/BMP-2 using a heparin-based hydrogel. Acta Biomaterialia, 7, 244 – 257.

Bone Marrow Derived Mesenchymal Stem Cells

Lee,S.H., Jang,A.S., Kim,Y.E., Cha,J.Y., Kim,T.H., Jung,S., Park,S.K., Lee,Y.K., Won,J.H. and Kim,Y.H. (2010) Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis. Resp. Res. 11, 16.

Murine Lung Tissue

Liu,G., Friggeri,A., Yang,Y., Milosevic,J., Ding,Q., Thannickal,V.J., Kaminski,N. and Abraham,E. (2010) miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. The Journal of experimental medicine, 207, 1589.

Lung Tissue

Li,M., Krishnaveni,M.S., Li,C., Borok,Z. and Minoo,P. (2010) Epithelial-Specific Deletion Of Transforming Growth Factor-2 TGF2) Receptor Type II (T2RII) In The Lung Confers Relative Resistance To Bleomycin Injury. American Journal of Respiratory and Critical Care Medicine, 181, A3525.

Fibroblasts and Connective Tissue

Lin,Y.K. and Kuan,C.Y. (2010) Development of 4-hydroxyproline analysis kit and its application to collagen quantification. Food Chemistry, 119, 1271-1277.

Porcine Chondrocytes and Osteoblasts

Lin,Y.Y., Tanaka,N., Ohkuma,S., Iwabuchi,Y., Tanne,Y., Kamiya,T., Kunimatsu,R., Huang,Y.C., Yoshioka,M. and Mitsuyoshi,T. (2010) Applying an excessive mechanical stress alters the effect of subchondral osteoblasts on chondrocytes in a co-culture system. European Journal of Oral Sciences, 118, 151-158.

Murine Lung Tissue

Liu,X., Li,F., Sun,S.Q., Thangavel,M., Kaminsky,J., Balazs,L. and Ostrom,R.S. (2010) Fibroblast specific expression of AC6 enhances ss-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology,298, L819 – L829.

Murine Lung Tissue and Fibroblasts

Liu,F., Mih,J.D., Shea,B.S., Kho,A.T., Sharif,A.S., Tager,A.M. and Tschumperlin,D.J. (2010) Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. The Journal of Cell Biology, 190, 693 – 706.

Murine Lung Tissue

Lo Re,S., Dumoutier,L., Couillin,I., Van Vyve,C., Yakoub,Y., Uwambayinema,F., Marien,B., van den Brûle,S., Van Snick,J. and Uyttenhove,C. (2010) IL-17A-Producing γδ T and Th17 Lymphocytes Mediate Lung Inflammation but Not Fibrosis in Experimental Silicosis. The Journal of Immunology, 184, 6367.

Osteoblastic Cell Cultures

Lozano,D., Manzano,M., Doadrio,J.C., Salinas,A.J., Vallet-RegíM., Gómez-Barrena,E. and Esbrit,P. (2010)

Osteostatin-loaded bioceramics stimulate osteoblastic growth and differentiation. Acta Biomaterialia, 6, 797-803.

Human Gingival Fibroblasts

Lu,H.K., Tseng,C.C., Lee,Y.H., Li,C.L. and Wang,L.F. (2010) Flutamide inhibits nifedipine-and interleukin-1 -induced collagen overproduction in gingival fibroblasts. Journal of Periodontal Research, 45, 451 - 457.

Rat Aortic Endothelial Cells and Rat Aortic Smooth Muscle Cells

Lu,J., Khang,D. and Webster,T.J. (2010) Greater endothelial cell responses on submicron and nanometer rough titanium surfaces. Journal of Biomedical Materials Research Part A, 94, 1042-1049.

Human Lung Fibroblasts

Lu,Y., Azad,N., Wang,L., Iyer,A.K.V., Castranova,V., Jiang,B-H. and Rojanasakul,Y. (2010) Phosphatidylinositol-3-Kinase/Akt Regulates Bleomycin-Induced Fibroblast Proliferation and Collagen Production. American Journal of Respiratory Cell and Molecular Biology, 42, 432 – 441.

Murine Colonic Tissue

Ma,Y., Guan,Q., Bai,A., Weiss,C.R., Hillman,C.L., Ma,A., Zhou,G., Qing,G. and Peng,Z. (2010) Targeting TGF- ß1 by employing a vaccine ameliorates fibrosis in a mouse model of chronic colitis. Inflammatory Bowel Diseases, 16, 1040-1050.

Lung Tissue

McDonald,J., Wright,M.R., Wright,C.D., Kuehl,P.J., Duncan,M. and Doyle-Eisele,M. (2010) GS-9450 A Novel Caspase Inhibitor Provides Protection Against Bleomycin Induced Pulmonary Fibrosis By Inhibition Of Apoptosis. American Journal of Respiratory and Critical Care Medicine, 181, A1053.

Murine Colon Extracts

Melon,A. and Wang,A. (2010) Infection with Hymenolepis diminuta Is More Effective than Daily Corticosteroids in

Blocking Chemically Induced Colitis in Mice. J Biomed Biotechnol., 2010, 384523.

Pancreatic Stellate Cells

Morishita,K., Shimizu,K., Haruta,I., Kawamura,S., Kobayashi,M. and Shiratori,K. (2010) Engulfment of Gram-Positive Bacteria by Pancreatic Stellate Cells in Pancreatic Fibrosis. Pancreas, 39, 1002 – 1007.

Murine Lung Tissue

Murray,L.A., Chen,Q., Kramer,M.S., Hesson,D.P., Argentieri,R.L., Peng,X., Gulati,M., Homer,R.J., Russell,T. and van Rooijen,N. (2010) TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. The International Journal of Biochemistry & Cell Biology, 43, 154 – 162.

Developing Tissue Engineered Cartilage Constructs

Natoli,R.M., Skaalure,S., Bijlani,S., Chen,K.X., Hu,J. and Athanasiou,K.A. (2010) Intracellular Na+ and Ca2+ modulation increases the tensile properties of developing engineered articular cartilage. Arthritis & Rheumatism, 62, 1097-1107.

Human and Murine Lung Tissue

Odajima,N., Betsuyaku,T., Nagai,K., Moriyama,C., Wang,D.H., Takigawa,T., Ogino,K., Nishimura,M., Xu,D.Q. and Luo,Y. (2010) The role of Catalase in Pulmonary Fibrosis. Respiratory Research, 11, 183.

Murine Lung Tissue

Ohbayashi,M., Suzuki,M., Yashiro,Y., Fukuwaka,S., Yasuda,M., Kohyama,N., Kobayashi,Y. and Yamamoto,T. (2010) Induction of pulmonary fibrosis by methotrexate treatment in mice lung in vivo and in vitro. The Journal of Toxicological Sciences, 35, 653-661.

Nasal Polyp-Derived Fibroblasts

Park,H.H., Cho,J.S., Park,I.H., Kim,Y.D. and Lee,H.M. (2010) The Effect Of Macrolides On Myofibroblast Differentiation And Collagen Production In Nasal Polyp-Derived Fibroblasts. American Journal of Respiratory and Critical Care Medicine, 181, A4213.

Nasal Polyp-Derived Fibroblasts

Park,H.H., Park,I.H., Cho,J.S., Lee,Y.M. and Lee,H.M. (2010) The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. American Journal of Rhinology & Allergy, 24, 348-353.

Murine MC3T3-E1 Calvarial Preosteoblasts

Pedraza,C.E., Marelli,B., Chicatun,F., McKee,M.D. and Nazhat,S.N. (2010) An In Vitro Assessment of a Cell-Containing Collagenous Extracellular Matrix-like Scaffold for Bone Tissue Engineering. Tissue Engineering Part A, 16, 781.

Human Lung Fibroblasts

Pegorier,S., Campbell,G.A., Kay,A.B. and Lloyd,C.M. (2010) Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-ß1 in normal human lung fibroblasts (NHLF). Respir Res. 2010; 11, 85.

Murine Lung Tissue

Phillips,J.E., Anand,M. and Chapman,R.W. (2010) Combined Cigarette Smoke And Viral Challenge Produces Synergistic Effects On Mouse Pulmonary Pathology. American Journal of Respiratory and Critical Care Medicine, 181, A1995.

Rat Mesenchymal Stem Cells

Pereira,I.H.L., Ayres,E., Patrício,P.S., Góes,G., Gomide,V.S., Junior,E.P. and Oréfice,R.L. (2010)

Photopolymerizable and injectable polyurethanes for biomedical applications: synthesis and biocompatibility. Acta Biomaterialia, 6, 3056 - 3066.

Bone Marrow Derived Mesenchymal Stem Cells

Ramaswamy,S., Gottlieb,D., Engelmayr Jr,G.C., Aikawa,E., Schmidt,D.E., Gaitan-Leon,D.M., Sales,V.L., Mayer Jr,J.E. and Sacks,M.S. (2010) The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials, 31, 1114-1125.

Murine Skin Tissue

Rankin,A.L., Mumm,J.B., Murphy,E., Turner,S., Yu,N., McClanahan,T.K., Bourne,P.A., Pierce,R.H., Kastelein,R. and Pflanz,S. (2010) IL-33 Induces IL-13-Dependent Cutaneous Fibrosis. The Journal of Immunology, 184, 1526.

Collagen Gels and Cellularized (Normal Human Lung Fibroblasts) Collagen Gels

Raub,C.B., Putnam,A.J., Tromberg,B.J. and George,S.C. (2010) Predicting bulk mechanical properties of

cellularized collagen gels using multiphoton microscopy. Acta Biomaterialia, 6, 4657 - 4665.

Murine Fibroblasts

Reich,N., Maurer,B., Akhmetshina,A., Venalis,P., Dees,C., Zerr,P., Palumbo,K., Zwerina,J., Nevskaya,T. and Gay,S. (2010) The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis. Arthritis & Rheumatism, 62, 280-290.

Murine Lung Tissue

Riteau,N., Gasse,P., Fauconnier,L., Gombault,A., Couegnat,M., Fick,L., Kanellopoulos,J., Quesniaux,V.F.J., Marchand-Adam,S. and Crestani,B. (2010) Extracellular ATP is a Danger Signal Activating P2X7 Receptor in Lung Inflammation and Fibrosis. American Journal of Respiratory and Critical Care Medicine, 182, 774 - 783.

Murine Lung Tissue

Ryu,J., Heldt,G.P., Nguyen,M., Gavrialov,O. and Haddad,G.G. (2010) Chronic hypercapnia alters lung matrix composition in mouse pups. Journal of Applied Physiology, 109, 203.

Rabbit Bone Marrow Stem Cells

Sahoo,S., Ang,L.T., Goh,J.C.H. and Toh,S.L. (2010) Bioactive nanofibers for fibroblastic differentiation of mesenchymal precursor cells for ligament/tendon tissue engineering applications. Differentiation, 79, 102-110.

Biohybrid Scaffold Containing Mesenchymal Progenitor Cells

Sahoo,S., Toh,S.L. and Goh,J.C.H. (2010) A bFGF-releasing silk/PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells. Biomaterials, 31, 2990 – 2998.

Bone Marrow Stem Cells

Sahoo,S., Ang,L.T., Goh,J.C.H. and Toh,S.L. (2010) Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications. Journal of Biomedical Materials Research Part A, 93, 1539-1550.

Ovine Peripheral Blood Endothelial Progenitor Cells

Sales,V.L., Mettler,B.A., Engelmayr Jr,G.C., Aikawa,E., Bischoff,J., Martin,D.P., Exarhopoulos,A., Moses,M.A., Schoen,F.J. and Sacks,M.S. (2010) Endothelial Progenitor Cells as a Sole Source for Ex Vivo Seeding of Tissue-Engineered Heart Valves. Tissue Engineering Part A, 16, 257.

Rabbit Patella Tendon Fibroblasts

Sawaguchi,N., Majima,T., Funakoshi,T., Shimode,K., Harada,K., Minami,A. and Nishimura,S.I. (2010) Effect of cyclic three-dimensional strain on cell proliferation and collagen synthesis of fibroblast-seeded chitosan-hyaluronan hybrid polymer fiber. Journal of Orthopaedic Science, 15, 569-577.

Murine Equine Suspensory Ligament

Schnabel,L.V., Mohammed,H.O., Jacobson,M.S. and Fortier,L.A. (2010) Effects of platelet rich plasma and acellular bone marrow on gene expression patterns and DNA content of equine suspensory ligament explant cultures. Equine Veterinary Journal, 40, 260-265.

Bronchiolar Lavage Fluid

Schneider,D.J., Lindsay,J.C., Zhou,Y., Molina,J.G. and Blackburn,M.R. (2010) Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease. The FASEB Journal, 24, 70.

Murine Lung Tissue

Schütze,N., Lehmann,I., Bonisch,U., Simon,J.C. and Polte,T. (2010) Exposure to Mycotoxins Increases the Allergic Immune Response in a Murine Asthma Model. American Journal of Respiratory and Critical Care Medicine, 181, 1188 – 1199.

Human Lung Tissue

Senoo,T., Hattori,N., Tanimoto,T., Furonaka,M., Ishikawa,N., Fujitaka,K., Haruta,Y., Murai,H., Yokoyama,A. and Kohno,N. (2010) Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis. British Medical Journal, 65, 334.

Human Fibroblasts

Seo,Y.K., Jung,S.H., Song,K.Y., Park,J.K. and Park,C.S. (2010) Anti-photoaging effect of fermented rice bran extract on UV-induced normal skin fibroblasts. European Food Research and Technology, 231, 163-169.

Murine Skin and Lung Tissue

Servettaz,A., Kavian,N., Nicco,C., Deveaux,V., Chereau,C., Wang,A., Zimmer,A., Lotersztajn,S., Weill,B. and Batteux,F. (2010) Targeting the Cannabinoid Pathway Limits the Development of Fibrosis and Autoimmunity in a Mouse Model of Systemic Sclerosis. American Journal of Pathology, 177, 187 – 196.

Human Airway Fibroblasts

Sidhu,S.S., Yuan,S., Innes,A.L., Kerr,S., Woodruff,P.G., Hou,L., Muller,S.J. and Fahy,J.V. (2010) Roles of epithelial cell-derived periostin in TGF- activation, collagen production, and collagen gel elasticity in asthma. Proceedings of the National Academy of Sciences, 107, 14170 – 14175.

Murine Lung Tissue

Smith,M.R., Gangireddy,S.R., Narala,V.R., Hogaboam,C.M., Standiford,T.J., Christensen,P.J., Kondapi,A.K. and Reddy,R.C. (2010) Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury. American Journal of Physiology- Lung Cellular and Molecular Physiology,298, L616 – L625.

Murine Lung Tissue

Song,J.S., Kang,C.M., Kang,H.H., Yoon,H.K., Kim,Y.K., Kim,K.H., Moon,H.S. and Park,S.H. (2010) Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis. Experimental & molecular medicine, 42, 465.

Human Left Diaphragmatic Tendon

Steigman,S.A., Oh,J.T., Almendinger,N., Javid,P., LaVan,D. and Fauza,D. (2010) Structural and biomechanical characteristics of the diaphragmatic tendon in infancy and childhood: an initial analysis. Journal of pediatric surgery, 45, 1455-1458.

Murine Lung Tissue

Stockmann,C., Kerdiles,Y., Nomaksteinsky,M., Weidemann,A., Takeda,N., Doedens,A., Torres-Collado,A.X., Iruela-Arispe,L., Nizet,V. and Johnson,R.S. (2010) Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis. Proceedings of the National Academy of Sciences, 107, 4329.

Fibroblasts and Myofibroblasts

Suresh,M.V., Adapala,R.K., Hogaboam,C.M., Narala,V.R. and Reddy,R.C. (2010) Nitrated Fatty Acids Inhibit Fibroblast-to-Myofibroblast Transdifferentiation Through PPAR-3 And SMAD 2/3 Signaling Pathways. American Journal of Respiratory and Critical Care Medicine, 181, A3534.

Normal Human Dermal Fibroblasts

Suwantong,O., Ruktanonchai,U. and Supaphol,P. (2010) In vitro biological evaluation of electrospun cellulose acetate fiber mats containing asiaticoside or curcumin. Journal of Biomedical Materials Research Part A, 94, 1216-1225.

Surgical Sponges Impregnated with Plasmid

Sweetwyne,M.T., Pallero,M.A., Lu,A., Van Duyn Graham,L. and Murphy-Ullrich,J.E. (2010) The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling. American Journal of Pathology,177, 1710 - 1724.

Articular Cartilage

Szarko,M., Muldrew,K. and Bertram,J.E.A. (2010) Freeze-thaw effects on the dynamic mechanical properties of articular cartilage. BMC Musculoskeletal Disorders, 11, 231.

Human Tenon’s Fibroblasts

Tappeiner,C., Meyenberg,A., Goldblum,D., Mojon,D., Zingg,J.M., Nesaretnam,K., Kilchenmann,M. and Frueh,B.E. (2010) Antifibrotic effects of tocotrienols on human Tenon’s fibroblasts. Graefe's Archive for Clinical and Experimental Ophthalmology, 248, 65-71.

Rat Skin Tissue

Tsuda,K., Nakatani,T., Sugama,J., Okuwa,M. and Sanada,H. (2010) Influence of the timing of switching a protein-free to a protein-containing diet on the wound healing process in a rat all-layer skin defect. International Wound Journal, 7, 135-146.

Normal Human dermal Fibroblasts (NHDFs)

Tsuji-Naito,K., Ishikura,S., Akagawa,M. and Saeki,H. (2010) α-Lipoic acid induces collagen biosynthesis involving prolyl hydroxylase expression via activation of TGF-ß-Smad signaling in human dermal fibroblasts. Connective Tissue Research, 51, 378-387.

Human Lung Fibroblasts (MRC-5)

Tung,J.N., Lang,Y.D., Wang,L.F. and Chen,C.M. (2010) Paraquat increases connective tissue growth factor and collagen expression via angiotensin signaling pathway in human lung fibroblasts. Toxicology in Vitro, 24, 803-808.

Lamb Cervical Trachea

Turner,C.G.B., Klein,J.D., Ahmed,A., Zurakowski,D. and Fauza,D.O. (2010) A Large Animal Model of the Fetal Tracheal Stenosis/Atresia Spectrum. Journal of Surgical Research, doi: 10.1016/j.jss.2010.02.037.

Murine Lung Tissue

Turpin,E.A., Antao-Menezes,A., Cesta,M.F., Mangum,J.B., Wallace,D.G., Bermudez,E. and Bonner,J.C. (2010) Respiratory syncytial virus infection reduces lung inflammation and fibrosis in mice exposed to vanadium pentoxide. Respiratory Research, 11, 20.

Murine Lung Tissue

Udalov,S., Dumitrascu,R., Pullamsetti,S.S., Al-tamari,H.M., Weissmann,N., Ghofrani,H.A., Guenther,A., Voswinckel,R., Seeger,W. and Grimminger,F. (2010) Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice. BMC Pulmonary Medicine, 10, 26.

Bovine Primary Fibroblasts

Urciuolo,F., Imparato,G., Palmiero,C., Trilli,A. and Netti,P.A. (2010) Effect of process conditions on the growth of 3D dermal-equivalent tissue obtained by micro tissue precursor assembly. Tissue Engineering Part C, doi:10.1089/ten.TEC.2010.0355.

Rat Glomeruli and Cultured Mesangial Cells

Urushihara,M., Takamatsu,M., Shimizu,M., Kondo,S., Kinoshita,Y., Suga,K., Kitamura,A., Matsuura,S., Yoshizumi,M. and Tamaki,T. (2010) ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis. American Journal of Physiology- Renal Physiology, 298, F167 – F176.

Murine Lung Tissue, Murine Lung Primary Fibroblasts, Human Fetal Lung Fibroblasts HFL-1 Cell Line

van den Brule,S., Wallemme,L., Uwambayinema,F., Huaux,F. and Lison,D. (2010) The D prostanoid (DP) receptor agonist BW245C ((4S)-(3-[(3R, S)-3-cyclohexyl-3-hydroxypropyl]-2, 5-dioxo)-4-imidazolidineheptanoic acid) inhibits fibroblast proliferation and bleomycin-induced lung fibrosis in mice. Journal of Pharmacology and Experimental Therapeutics, doi:10.1124/jpet.110.169250.

Mouse Embryonic Fibroblasts

Van Duyn Graham,L., Sweetwyne,M.T., Pallero,M.A. and Murphy-Ullrich,J.E. (2010) Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix. Journal of Biological Chemistry, 285, 7067 - 7078.

Murine Lung Tissue

Vannella,K.M., Luckhardt,T.R., Wilke,C.A., van Dyk,L.F., Toews,G.B. and Moore,B.B. (2010) Latent Herpesvirus Infection Augments Experimental Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 181, 465.

Porcine Fibroblasts

Vavken,P., Joshi,S.M. and Murray,M.M. (2010) Fibrin concentration affects ACL fibroblast proliferation and collagen synthesis. The Knee,18, 42 - 46.

Murine Skin Fibroblasts

Wang,J.C., Lai,S., Guo,X., Zhang,X., de Crombrugghe,B., Arnett,F. and Zhou,X. (2010) Attenuation of fibrosis in vitro and in vivo with Sparc siRNA. Arthritis Research & Therapy, 12, R60.

Human Lung Fibroblasts

Wang,L., Castranova,V., Mishra,A., Chen,B., Mercer,R.R., Schwegler-Berry,D. and Rojanasakul,Y. (2010) Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies. Particle and Fibre Toxicology, 7, 31.

Murine Lung Tissue

Wang,Q., Li,H., Yao,Y., Xia,D. and Zhou,J. (2010) The Overexpression of Heparin-Binding Epidermal Growth Factor Is Responsible for Th17-Induced Airway Remodeling in an Experimental Asthma Model. The Journal of Immunology, 185, 834 -841.

Porcine Aortic Heart Valve Leaflets

Warnock,J.N., Gamez,C.A.P., Metzler,S.A., Chen,J., Elder,S.H. and Liao,J. (2010) Vasoactive Agents Alter the Biomechanical Properties of Aortic Heart Valve Leaflets in a Time-Dependent Manner. Journal of Heart Valve Disease, 19, 86-96.

Human Primary Osteoblast Cells

Whiteside,P., Matykina,E., Gough,J.E., Skeldon,P. and Thompson,G.E. (2010) In vitro evaluation of cell proliferation and collagen synthesis on titanium following plasma electrolytic oxidation. Journal of Biomedical Materials Research Part A, 94, 38-46.

Murine Bronchoalveolar Lavage Fluid

Wilson,M.S., Madala,S.K., Ramalingam,T.R., Gochuico,B.R., Rosas,I.O., Cheever,A.W. and Wynn,T.A. (2010) Bleomycin and IL-1β-mediated pulmonary fibrosis is IL-17A dependent. Journal of Experimental Medicine, 207, 535 – 552.

Rabbit Bone Marrow Mesenchymal Stem Cells

Xie,J., Han,Z., Naito,M., Maeyama,A., Kim,S.H., Kim,Y.H. and Matsuda,T. (2010) Articular cartilage tissue engineering based on a mechano active scaffold made of poly (L lactide co caprolactone): In vivo performance in adult rabbits. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 94, 80-88.

Murine Monocyte/Macrophage Cell Line (RAW264.7)

Yahyouche,A., Zhidao,X. and Czernuszka,J. (2011) Macrophage-Mediated Degradation of Crosslinked Collagen Scaffolds. Acta Biomaterialia, 7, 278 - 286.

Kidney Epithelial Cells

Yang,L., Besschetnova,T.Y., Brooks,C.R., Shah,J.V. and Bonventre,J.V. (2010) Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nature Medicine, 16, 535-543.

Primary Fibroblasts and Myofibroblasts

Zanotti,S., Gibertini,S. and Mora,M. (2010) Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF- ß1 treatment. Cell and Tissue Research, 339, 397-410.

Murine Tendon Stem Cells (TSCs) and Tenocytes

Zhang,J., Pan,T., Liu,Y. and Wang,J.H. (2010) Mouse treadmill running enhances tendons by expanding the pool of tendon stem cells (TSCs) and TSC related cellular production of collagen. Journal of Orthopaedic Research, 28, 1178-1183.

Murine Tendon Stem Cells

Zhang,J. and Wang,J.H.C. (2010) Platelet-Rich Plasma Releasate Promotes Differentiation of Tendon Stem Cells Into Active Tenocytes. The American Journal of Sports Medicine, doi: 10.1177/0363546510376750.

Murine Lung Samples

Zhang,T., Srivastava,K., Wen,M.C., Yang,N., Cao,J., Busse,P., Birmingham,N., Goldfarb,J. and Li,X.M. (2010) Pharmacology and immunological actions of a herbal medicine ASHMITM on allergic asthma. Phytotherapy Research, 24, 1047-1055.

Human Scleral Fibroblasts

Zhou,X., Huang,Q., An,J., Lu,R., Qin,X., Jiang,L., Li,Y., Wang,J., Chen,J. and Qu,J. (2010) Genetic Deletion of the Adenosine A2A Receptor Confers Postnatal Development of Relative Myopia in Mice. Investigative Ophthalmology & Visual Science, 51, 4362 – 4370.

Murine Embryo Fibroblasts

Zito,E., Melo,E.P., Yang,Y., Wahlander,A., Neubert,T.A. and Ron,D. (2010) Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin. Molecular Cell, 40, 787-797.

2009

Allograft Collagen

Abreu,E.L., Palmer,M.P. and Murray,M.M. (2009) Storage conditions do not have detrimental effect on allograft collagen or scaffold performance. Cell and Tissue Banking, 10, 333-340.

Murine Colon

Alexandra,M., Arthur,W., Van,P. and Derek,M. (2009) Infection with Hymenolepis diminuta Is More Effective than Daily Corticosteroids in Blocking Chemically Induced Colitis in Mice. Journal of Biomedicine and Biotechnology, doi: 10.1155/2010/384523.

Fibroblast Cells

Aramwit,P., Kanokpanont,S., De-Eknamkul,W., Kamei,K. and Srichana,T. (2009) The Effect of Sericin with Variable Amino-Acid Content from Different Silk Strains on the Production of Collagen and Nitric Oxide. Journal of Biomaterials Science, Polymer Edition, 20, 1295-1306.

Fibroblast Populated Fibrin Gels

Balestrini,J.L. and Billiar,K.L. (2009) Magnitude and Duration of Stretch Modulate Fibroblast Remodeling. Journal of Biomechanical Engineering, 131, 051005.

Osteoblasts

Ball,M.D., O’Connor,D. and Pandit,A. (2009) Use of tissue transglutaminase and fibronectin to influence osteoblast responses to tricalcium phosphate scaffolds. Journal of Materials Science: Materials in Medicine, 20, 113-122.

Murine Lung Tissue

Banerjee,E.R., Jiang,Y., Henderson,W.R., Latchman,Y. and Papayannopoulou,T. (2009) Absence of α4 but not ß2 integrins restrains development of chronic allergic asthma using mouse genetic models. Experimental Hematology, 37, 715-727.

Murine Renal Tissue and a Proximal Tubule Epithelial Cell Line (HK-2 Cells)

Bani-Hani,A.H., Leslie,J.A., Asanuma,H., Dinarello,C.A., Campbell,M.T., Meldrum,D.R., Zhang,H., Hile,K. and Meldrum,K.K. (2009) IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis. Kidney International, 76, 500-511.

Mesenchymal Stem Cells on Chitosan Scaffold

Breyner, N.M., Hell, R.C.R., Carvalho, L.R.P., Machado, C.B., Peixoto Filho, I.N., Valério, P., Pereira, M.M. and Goes, A.M. (2009) Effect of a Three-Dimensional Chitosan Porous Scaffold on the Differentiation of Mesenchymal Stem Cells into Chondrocytes. Cells Tissues Organs, doi: 10.1159/000231472.

NIH 3T3 Fibroblasts

Chen,M., Michaud,H. and Bhowmick,S. (2009) Controlled Vacuum Seeding as a Means of Generating Uniform Cellular Distribution in Electrospun Polycaprolactone (PCL) Scaffolds. Journal of Biomechanical Engineering, 131, 074521.

Rat Dorsal Tissue

Chung,P.S., Shin,J.I., Chang,S.Y. and Ahn,J.C. (2009) Histological Change and Collagen Formation on Laser Wounded Rat using 808 Diode Laser and CO2 Laser. Science for the Life of Issue 1, 15, 81-86.

Murine Lung Tissue

Couillin,I., Vasseur,V., Charron,S., Gasse,P., Tavernier,M., Guillet,J., Lagente,V., Fick,L., Jacobs,M. and Coelho,F.R. (2009) IL-1R1/MyD88 Signaling Is Critical for Elastase-Induced Lung Inflammation and Emphysema. The Journal of Immunology, 183, 8195.

Human Mucosal Myofibroblasts

Di Sabatino,A., Jackson,C.L., Pickard,K.M., Buckley,M., Rovedatti,L., Leakey,N.A.B., Picariello,L., Cazzola,P., Monteleone,G. and Tonelli,F. (2009) Transforming growth factor ß signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures. British Medical Journal, 58, 777-789.

Murine Lung Tissue

Du,G., Jin,L., Han,X., Song,Z., Zhang,H. and Liang,W. (2009) Naringenin: A Potential Immunomodulator for Inhibiting Lung Fibrosis and Metastasis. Cancer Research, 69, 3205.

Porcine Bone Marrow-Derived Mesenchymal Cells (bMSCs)

Elder,S.H., Cooley Jr,A.J., Borazjani,A., Sowell,B.L., To,H. and Tran,S.C. (2009) Production of Hyaline-like Cartilage by Bone Marrow Mesenchymal Stem Cells in a Self-Assembly Model. Tissue Engineering Part A, 15, 3025 – 3036.

Murine Lung Tissue

Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E. and Crimi,N. (2009) 16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-Induced Lung Injury and Fibrosis. American Journal of Respiratory Cell and Molecular Biology, 41, 50 – 58.

Skeletal Muscle Construct from C2C12 Myoblast Cell Line

Fujita,H., Shimizu,K. and Nagamori,E. (2009) Novel method for fabrication of skeletal muscle construct from the C2C12 myoblast cell line using serum-free medium AIM-V. Biotechnology and Bioengineering, 103, 1034-1041.

Murine Lung Tissue

Glass,W.G., Argentieri,R.L., Bracht,M., Farrell,F.X., Das,A.M., Del Vecchio,A.M., Hogaboam,C.M. and Murray,L.A.

(2009) Generation of bleomycin-induced lung fibrosis is independent of IL-16. Cytokine, 46, 17–23.

Atherosclerotic Carotid Plaques

Gonçalves,I., Stollenwerk,M.M., Lindholm,M.W., Dias,N., Pedro,L.M., Fernandes,J.F., Moses,J., Fredrikson,G.N., Nilsson,J. and Ares,M.P.S. (2009) Activator protein-1 in carotid plaques is related to cerebrovascular symptoms and cholesteryl ester content. Cardiovascular Pathology, doi: 10.1016/j.carpath.2009.09.003.

Human Bone Marrow Stromal Cells

Green,D.W., Bolland,B.J.R.F., Kanczler,J.M., Lanham,S.A., Walsh,D., Mann,S. and Oreffo,R.O.C. (2009) Augmentation of skeletal tissue formation in impaction bone grafting using vaterite microsphere biocomposites. Biomaterials, 30, 1918-1927.

Murine Colon Tissue

Guan,Q., Ma,Y., Hillman,C.L., Ma,A., Zhou,G., Qing,G. and Peng,Z. (2009) Development of recombinant vaccines against IL-12/IL-23 p40 and in vivo evaluation of their effects in the downregulation of intestinal inflammation in murine colitis. Vaccine, 27, 7096 – 7104.

Articular Cartilages from Human Knee Joint

Han,D.W., Bae,J.Y. and Hyon,S.H. (2009) Biochemical and Histological Evaluations of Articular Cartilages Preserved in Cold Storage Solution Containing Green Tea Catechin, EGCG. Tissue Engineering and Regenerative Medicine, 6, 380-387.

Murine Asthma Model

Hansen,G. (2009) Different role of CD30 in the development of acute and chronic airway inflammation in a murine asthma model. Eur.J.Immunol, 39, 1736-1742.

Bladder Smooth Muscle Cells

Heise,R.L., Ivanova,J., Parekh,A. and Sacks,M.S. (2009) Generating Elastin-Rich Small Intestinal Submucosa-Based Smooth Muscle Constructs Utilizing Exogenous Growth Factors and Cyclic Mechanical Stimulation. Tissue Engineering Part A, 15, 3951-3960.

Rat Renal Tissue

He,L., Qi,Y., Rong,X., Jiang,J., Yang,Q., Yamahara,J., Murray,M. and Li,Y. (2009) The Ayurvedic medicine Salacia oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling. Evidence-based Complementary and Alternative Medicine, doi: 10.1093/ecam/nep095.

Murine Lung Mesenchymal Cells and Myofibroblasts

Hecker,L., Vittal,R., Jones,T., Jagirdar,R., Luckhardt,T.R., Horowitz,J.C., Pennathur,S., Martinez,F.J. and Thannickal,V.J. (2009) NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nature Medicine, 15, 1077-1081.

Human Skin Fibroblasts

Hemmatazad,H., Rodrigues,H.M., Maurer,B., Brentano,F., Pileckyte,M., Distler,J.H.W., Gay,R.E., Michel,B.A., Gay,S. and Huber,L.C. (2009) Histone deacetylase 7, a potential target for the antifibrotic treatment of systemic sclerosis. Arthritis & Rheumatism, 60, 1519-1529.

Rabbit Subcutaneous Implant Model

Henry,J.A., Burugapalli,K., Neuenschwander,P. and Pandit,A. (2009) Structural variants of biodegradable polyesterurethane in vivo evoke a cellular and angiogenic response that is dictated by architecture. Acta Biomaterialia, 5, 29-42.

Rat Cardiac Fibroblasts

Hermida,N., Lopez,B., Gonzalez,A., Dotor,J., Lasarte,J.J., Sarobe,P., Borras-Cuesta,F. and Diez,J. (2009) A synthetic peptide from transforming growth factor-β 1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats. Cardiovascular Research, 81, 601.

Murine Embryonic Fibroblasts and Primary Hepatocytes

Hosui,A., Kimura,A., Yamaji,D., Zhu,B., Na,R. and Hennighausen,L. (2009) Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-ß and STAT3 activation. Journal of Experimental Medicine, 206, 819 - 831.

Human Osteoarthritis Cartilage explants and a Rabbit Model of Osteoarthritis

Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2009) Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.

Mouse Osteoclasts

Idris,A.I., Greig,I.R., Bassonga-Landao,E., Ralston,S.H. and van't Hof,R.J. (2009) Identification of Novel Biphenyl Carboxylic Acid Derivatives as Novel Antiresorptive Agents that Do Not Impair Parathyroid Hormone-Induced Bone Formation. Endocrinology, 150, 5-13.

Human Term Fetal Membranes

Jabareen,M., Mallik,A.S., Bilic,G., Zisch,A.H. and Mazza,E. (2009) Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis. European Journal of Obstetrics and Gynecology, 144, 134-141.

Murine Lung Tissue

Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and Ishizaka,A. (2009) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual Lung of Mice. Journal of Surgical Research, 154, 336-344.

Murine Lung Tissue

Kanda,A., Driss,V., Hornez,N., Abdallah,M., Roumier,T., Abboud,G., Legrand,F., Staumont-SalléD., Quéant,S. and Bertout,J. (2009) Eosinophil-derived IFN- induces airway hyperresponsiveness and lung inflammation in the absence of lymphocytes. The Journal of Allergy and Clinical Immunology, 124, 573-582.

Rat Renal Tissue and Cultured Mesangial Cells

Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2009) Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrology Dialysis Transplantation, 24, 73-84.

Human Dermal Fibroblasts

Kim,H.J., Song,S.B., Lee,J.Y., Cho,B.K., Cho,D.H. and Park,H.J. (2009) Interleukin-18 Downregulates Collagen Production in Human Dermal Fibroblasts via ERK pathway. The Journal of Immunology, 182, 98-14.

Rat Ear Fibroblast Cells

Kim, J.-H. and Choi, J.-Y. (2009) Study on thermosensitivity of chitosan scaffold and on its effects on fibroblast proliferation in cell therapy for soft tissue augmentation. J. Kor. Oral Maxillofac. Surg., 35, 146-152.

Rat Common Bile Duct Fibroblasts

Kim,T.H., Moon,J.H., Savard,C.E., Kuver,R. and Lee,S.P. (2009) Effects of lipopolysaccharide on platelet-derived growth factor isoform and receptor expression in cultured rat common bile duct fibroblasts and cholangiocytes. Journal of Gastroenterology and Hepatology, 24, 1218-1225.

Osteoblastic MC3T3-E1 Cells

Kim,Y.H. and Choi,E.M. (2009) Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Phytotherapy Research, 23, 737-739.

Immobilised Matrix Vesicle Model

Kinugawa,M., Fukuzawa,S. and Tachibana,K. (2009) Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine. Journal of Bone and Mineral Metabolism, 27, 303-314.

Mouse and Human Lung Fibroblasts

Königshoff,M., Kramer,M., Balsara,N., Wilhelm,J., Amarie,O.V., Jahn,A., Rose,F., Fink,L., Seeger,W. and Schaefer,L. (2009) WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. The Journal of Clinical Investigation, 119, 772-787.

Murine Bone Marrow Mesenchymal Stem Cells

Kumamoto,M., Nishiwaki,T., Matsuo,N., Kimura,H. and Matsushima,K. (2009) Minimally-cultured Bone Marrow mesenchymal stem cells ameliorate fibrotic lung injury. European Respiratory Journal, doi:10.1183/ 09031936-00128508.

Mouse Breast Cell Line

Lee,C.G., Hartl,D., Lee,G.R., Koller,B., Matsuura,H., Da Silva,C.A., Sohn,M.H., Cohn,L., Homer,R.J. and Kozhich,A.A. (2009) Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. Journal of Experimental Medicine, 206, 1149-1166.

Chondrocytes

Lee,N.K., Oh,H.J., Hong,C.M., Suh,H. and Hong,S.H. (2009) Comparison of the synthetic biodegradable polymers, polylactide (PLA), and polylactic-co-glycolic acid (PLGA) as scaffolds for artificial cartilage. Biotechnology and Bioprocess Engineering, 14, 180-186.

Murine Lung Tissue

Lee,J., Reddy,R., Barsky,L., Scholes,J., Chen,H., Shi,W. and Driscoll,B. (2009) Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, 296, L57.

Human Dermal Fibroblasts

Lefler,A. and Ghanem,A. (2009) Development of bFGF-Chitosan Matrices and Their Interactions with Human Dermal Fibroblast Cells. Journal of Biomaterials Science, Polymer Edition, 20, 1335-1351.

Connective Tissue and Fibroblasts

Lin,Y.K. and Kuan,C.Y. (2009) Development of 4-hydroxyproline analysis kit and its application to collagen quantification. Food Chemistry, doi: 10.1016/j.foodchem.2009.08.009.

Rat Hepatic Stellate Cells

Lin,Y.L., Lin,C.Y., Chi,C.W. and Huang,Y.T. (2009) Study on antifibrotic effects of curcumin in rat hepatic stellate cells. Phytotherapy Research, 23, 927-932.

Rat Hepatic Stellate Cell Line (HSC-T6)

Lin,Y.L., Wu,C.F. and Huang,Y.T. (2009) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of Gastroenterology and Hepatology, 24, 453-461.

Human Myocardium

Lopez,B., Querejeta,R., Gonzalez,A., Beaumont,J., Larman,M. and Diez,J. (2009) Impact of Treatment on Myocardial Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure. Hypertension, 53, 236-242.

Bone Marrow Cultures and Osteoblastic MC3T3-E1 Cells

Lozano,D., de Castro,L.F., Dapía,S., Andrade-Zapata,I., Manzarbeitia,F., Ayvarez-Arroyo,M., Gómez-Barrena,E. and Esbrit,P. (2009) Role of Parathyroid Hormone-Related Protein in the Decreased Osteoblast Function in Diabetes-Related Osteopenia. Endocrinology, 150, 2027-2035.

Murine Lung Tissue

Manicone,A.M., Huizar,I. and McGuire,J.K. (2009) Matrilysin (Matrix Metalloproteinase-7) Regulates Anti-Inflammatory and Antifibrotic Pulmonary Dendritic Cells That Express CD103 αE ß7-Integrin). American Journal of Pathology, 175, 2319 – 2331.

Murine Lung Tissue

Markart,P., Luboeinski,T., Korfei,M., Schmidt,R., Wygrecka,M., Mahavadi,P., Mayer,K., Wilhelm,J., Seeger,W. and Guenther,A. (2009) Alveolar Oxidative Stress is Associated with Elevated Levels of Nonenzymatic Low-Molecular-Weight Antioxidants in Patients with Different Forms of Chronic Fibrosing Interstitial Lung Diseases. Antioxidants & Redox Signaling, 11, 227-240.

Human Fibrocytes

Mehrad,B., Burdick,M.D. and Strieter,R.M. (2009) Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis. International Journal of Biochemistry and Cell Biology, 41, 1708-1718.

Human Retinal Pigment (ARPE-19) Cell Line

Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2009) FAK Activation and the Role of Epithelial Membrane Protein 2 (EMP2) in Collagen Gel Contraction. Investigative Ophthalmology & Visual Science, 50, 462-469.

EpiDerm FT Engineered Skin, Murine Epidermal Cells (JB6 P+) and Immune-Competent Hairless SKH-1

Mice

Murray,A.R., Kisin,E., Leonard,S.S., Young,S.H., Kommineni,C., Kagan,V.E., Castranova,V. and Shvedova,A.A. (2009) Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology, 257, 161-171.

Murine Peritoneal Fibroblasts

Nakav,S., Kachko,L., Vorobiov,M., Rogachev,B., Chaimovitz,C., Zlotnik,M. and Douvdevani,A. (2009) Blocking adenosine A2A receptor reduces peritoneal fibrosis in two independent experimental models. Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfp041.

Bovine Chondrocytes Seeded in Non-Adherent Agarose Molds

Natoli,R.M., Revell,C.M. and Athanasiou,K.A. (2009) Chondroitinase ABC Treatment Results in Increased Tensile Properties of Self-Assembled Tissue Engineered Articular Cartilage. Tissue Engineering.Part A, 15, 3119 – 3128.

Murine Lung Tissue

Nicola,T., Hagood,J.S., James,M.L., MacEwen,M.W., Williams,T.A., Hewitt,M.M., Schwiebert,L., Bulger,A., Oparil,S. and Chen,Y.F. (2009) Loss of Thy-1 inhibits alveolar development in the newborn mouse lung. American Journal of Physiology- Lung Cellular and Molecular Physiology, 296, L738-L750.

Murine Lung Tissue

Niese,K.A., Collier,A.R., Hajek,A.R., Cederbaum,S.D., O'Brien,W.E., Wills-Karp,M., Rothenberg,M.E. and Zimmermann,N. (2009) Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunology, 10, 33.

Murine Lung Fibroblasts

Oga,T., Matsuoka,T., Yao,C., Nonomura,K., Kitaoka,S., Sakata,D., Kita,Y., Tanizawa,K., Taguchi,Y. and Chin,K. (2009) Prostaglandin F2 αreceptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-ß. Nature medicine, 15, 1426-1430.

Human Lung Fibroblasts

Okada,M., Suzuki,K., Matsumoto,M., Takada,K., Nakanishi,T., Horikoshi,H., Higuchi,T., Hosono,Y., Nakayama,M. and Ohsuzu,F. (2009) Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts. Journal of Clinical Pharmacy & Therapeutics, 34, 289-299.

Rat Calvariae Osteoblasts

Orriss,I.R., Key,M.L., Colston,K.W. and Arnett,T.R. (2009) Inhibition of osteoblast function in vitro by aminobisphosphonates. Journal of Cellular Biochemistry, 106, 109-118.

Swiss Mouse Intraplantar Region

Pareja-Santos,A., Saraiva,T.C., Costa,E.P., Santos,M.F., Zorn,T.T., Souza,V.M.O., Lopes-Ferreira,M. and Lima,C. (2009) Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation. International Journal of Experimental Pathology, 90, 34-43.

Human Dermal Fibroblasts

Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2009) Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. The Journal of investigative dermatology, 129, 843-850.

Rat Respiratory Tract

Pauluhn,J. (2009) Subchronic 13-week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects are determined by Density of Agglomerate Structures, not fibrillar Structures. Toxicological Sciences, doi: 10.1093/toxsci/kfp247.

Tissue Engineered Valve Constructs Seeded With Mesenchymal Stem Cells

Ramaswamy,S., Gottlieb,D., Engelmayr,G.C., Aikawa,E., Schmidt,D.E., Gaitan-Leon,D.M., Sales,V.L., Mayer,J.E. and Sacks,M.S. (2010) The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials, 31, 1114-1125.

Murine Lung Tissue

Ryman-Rasmussen,J.P., Tewksbury,E.W., Moss,O.R., Cesta,M.F., Wong,B.A. and Bonner,J.C. (2009) Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. American Journal of Respiratory Cell and Molecular Biology, 40, 349-358.

Dermal Fibroblasts

Saesoo,S., Sramala,I., Soottitantawat,A., Charinpanitkul,T. and Ruktanonchai,U.R. (2009) Enhanced stability and in vitro bioactivity of surfactant-loaded liposomes containing Asiatic Pennywort extract. Journal of Microencapsulation, doi: 10.3109/02652040903447686.

Human Heart Valves

Schenke-Layland,K., Stock,U.A., Nsair,A., Xie,J., Angelis,E., Fonseca,C.G., Larbig,R., Mahajan,A., Shivkumar,K., Fishbein,M.C. and MacLellan, W.R. (2009) Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix. European Heart Journal, 30, 2254-2265.

Human Foreskin Fibroblasts

Schenke-Layland,K., Rofail,F., Heydarkhan,S., Gluck,J.M., Ingle,N.P., Angelis,E., Choi,C.H., MacLellan,W.R., Beygui,R.E. and Shemin,R.J. (2009) The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix for regenerative medicine strategies. Biomaterials, 30, 4665-4675.

Mesenchymal Stem Cells

Schnabel,L.V., Lynch,M.E., van der Meulen,M.C.H., Yeager,A.E., Kornatowski,M.A. and Nixon,A.J. (2009) Mesenchymal stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons. Journal of Orthopaedic Research, 27, 1392-1398.

Anterior Cruciatge Ligament Cell and T-Lymophocytes on Composite Silk Scaffolds

Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2009) Increase in cell migration and angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research, 27, 495-503.

Murine Skin and Lung Tissue

Servettaz,A., Goulvestre,C., Kavian,N., Nicco,C., Guilpain,P., Chereau,C., Vuiblet,V., Guillevin,L., Mouthon,L. and Weill,B. (2009) Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse. The Journal of Immunology, 182, 5855-5864.

Murine Conjunctival Tissue

Shii,D., Nakagawa,S., Shinomiya,K., Yoshimi,M., Katsuta,O., Oda,T. and Nakamura,M. (2009) Cyclosporin A Eye Drops Inhibit Fibrosis and Inflammatory Cell Infiltration in Murine Type I Allergic Conjunctivitis without Affecting the Early-Phase Reaction. Current Eye Research, 34, 426-437.

Smooth Muscle Cells

Shin,J.W., Lee,Y.J., Heo,S.J., Park,S.A., Kim,S.H., Kim,Y.J., Kim,D.H. and Shin,J.W. (2009) Manufacturing of Multi-Layered Nanofibrous Structures Composed of Polyurethane and Poly (ethylene oxide) as Potential Blood Vessel Scaffolds. Journal of Biomaterials Science, Polymer Edition, 20, 5, 757-771.

Rat Myogenic Cells from Large Thigh Muscle

Stern,M.M., Myers,R.L., Hammam,N., Stern,K.A., Eberli,D., Kritchevsky,S.B., Soker,S. and Van Dyke,M. (2009) The influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of myogenic progenitor cells ex vivo. Biomaterials, 30, 2393-2399.

Mesenchymal Progenitor Cells (Fibrocytes)

Strieter,R.M., Keeley,E.C., Hughes,M.A., Burdick,M.D. and Mehrad,B. (2009) The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. Journal of leukocyte biology, 86, 1111-1118.

Mouse Osteoblastic Cell Line (MC3T3-E1)

Suh,K.S., Choi,E.M., Kwon,M., Chon,S., Oh,S., Woo,J.T., Kim,S.W., Kim,J.W. and Kim,Y.S. (2009) Kaempferol Attenuates 2-Deoxy-D-ribose-Induced Oxidative Cell Damage in MC3T3-E1 Osteoblastic Cells. Biological & Pharmaceutical Bulletin, 32, 746-749.

Rat Pancreatic Tissue

Suzuki,N., Masamune,A., Kikuta,K., Watanabe,T., Satoh,K. and Shimosegawa,T. (2009) Ellagic Acid Inhibits Pancreatic Fibrosis in Male Wistar Bonn/Kobori Rats. Digestive Diseases and Sciences, 54, 802-810.

Murine Patellar Tendons

Szczodry,M., Zhang,J., Lim,C., Davitt,H.L., Yeager,T., Fu,F.H. and Wang,J.H.C. (2009) Treadmill running exercise results in the presence of numerous myofibroblasts in mouse patellar tendons. Journal of Orthopaedic Research, 27, 1373-1378.

Human Embryonic Stem Cells (hESCs)

Toh,W.S., Guo,X-M., Choo,A.B., Lu,K., Lee,E.H. and Cao,T. (2009) Differentiation and Enrichment of Expandable Chondrogenic Cells from Human Embryonic Stem Cells in Vitro. Journal of Cellular and Molecular Medicine, doi:10.1111/j.1582-4934.2009.00762.x.

Murine Hepatic Tissue

Tong,Z.Y., Chen,R., Alt,D.S., Kemper,S., Perbal,B. and Brigstock,D.R. (2009) Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. Hepatology, 50, 939-947.

Rat Liver Tissue

Tsai,P.C., Fu,T.W., Chen,Y.M.A., Ko,T.L., Chen,T.H., Shih,Y.H., Hung,S.C. and Fu,Y.S. (2009) The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis. Liver Transplantation, 15, 484-495.

Rat Glomeruli and Cultured Mesangial Cells

Urushihara,M., Takamatsu,M., Shimizu,M., Kondo,S., Kinoshita,Y., Suga,K., Kitamura,A., Matsuura,S., Yoshizumi,M. and Tamaki,T. (2010) ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis. American Journal of Physiology- Renal Physiology, 298, F167 – F176.

Primary Human Cardiac Fibroblasts

Venkatachalam,K., Venkatesan,B., Valente,A.J., Melby,P.C., Nandish,S., Reusch,J.E.B., Clark,R.A. and Chandrasekar,B. (2009) Wisp1, a pro-mitogenic, pro-survival factor, mediates TNF-alpha stimulated cardiac fibroblast proliferation, but inhibits TNF-alpha-induced cardiomyocyte death. Journal of Biological Chemistry, 284, 14414-14427.

Murine Diaphragm

Vetrone,S.A., Montecino-Rodriguez,E., Kudryashova,E., Kramerova,I., Hoffman,E.P., Liu,S.D., Miceli,M.C. and Spencer,M.J. (2009) Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-ß. The Journal of Clinical Investigation, 119, 1583-1594.

Human Palmar Fascia Cells

Vi,L., Njarlangattil,A., Wu,Y., Gan,B.S. and O'Gorman,D.B. (2009) Type-1 collagen differentially alters beta-catenin accumulation in primary Dupuytren's Disease cord and adjacent palmar fascia cells. BMC Musculoskeletal Disorders, 10, 72.

Human Palmar Fascia Cells

Vi,L., Feng,L., Zhu,R.D., Wu,Y., Satish,L., Gan,B.S. and O'Gorman,D.B. (2009) Periostin differentially induces proliferation, contraction and apoptosis of primary Dupuytren's disease and adjacent palmar fascia cells. Experimental Cell Research, 315, 3574 – 3586.

Human Smooth Muscle Cells

Wang,C., Cen,L., Yin,S., Liu,Q., Liu,W., Cao,Y. and Cui,L. (2010) A small diameter elastic blood vessel wall prepared under pulsatile conditions from polyglycolic acid mesh and smooth muscle cells differentiated from adipose-derived stem cells. Biomaterials, 31, 621-630.

Murine Colonic Fibroblast Cells

Wang,H., Zhang,R., Wen,S., McCafferty,D.M., Beck,P.L. and MacNaughton,W.K. (2009) Nitric oxide increases Wnt-induced secreted protein-1 (WISP-1/CCN4) expression and function in colitis. Journal of Molecular Medicine, 87, 435-445.

Murine Calf Muscle

Watanuki,M., Kishimoto,K.N., Kotajima,S., Iwabuchi,S. and Kokubun,S. (2009) Effect of low-intensity pulsed ultrasound on scaffold-free ectopic bone formation in skeletal muscle. Upsala Journal of Medical Sciences, 114, 242-248.

Rat Stellate Liver Cell Line (HSC-T6)

Weng,T.C., Shen,C.C., Chiu,Y.T., Lin,Y.L., Kuo,C.D. and Huang,Y.T. (2009) Inhibitory effects of armepavine against hepatic fibrosis in rats. Journal of Biomedical Science, 16, 78.

Murine Lung Tissue

Wigenstam,E., Rocksén,D., Ekstrand-Hammarström,B. and Bucht,A. (2009) Treatment with dexamethasone or liposome-encapsuled vitamin E provides beneficial effects after chemical-induced lung injury. Inhalation Toxicology, 11, 958-964.

Murine Skin and Lung Tissue

Wu,M., Melichian,D.S., de la Garza,M., Gruner,K., Bhattacharyya,S., Barr,L., Nair,A., Shahrara,S., Sporn,P.H.S. and Mustoe,T.A. (2009) Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and Wound Healing. American Journal of Pathology, 175, 1041.

Murine Model of Scleroderma

Wu,M., Melichian,D.S., Chang,E., Warner-Blankenship,M., Ghosh,A.K. and Varga,J. (2009) Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ. American Journal of Pathology, 174, 519.

Rat Liver Tissue

Yasoshima,M., Sato,Y., Furubo,S., Kizawa,K., Sanzen,T., Ozaki,S., Harada,K. and Nakanuma,Y. (2009) Matrix proteins of basement membrane of intrahepatic bile ducts are degraded in congenital hepatic fibrosis and Caroli's disease No conflicts of interest were declared. The Journal of Pathology, 217, 442-451.

Porcine Hind Leg Tibial Osteochondral Explants

Yeow,C.H., Lau,S.T., Lee,P.V.S. and Goh,J.C.H. (2009) Damage and degenerative changes in menisci-covered and exposed tibial osteochondral regions after simulated landing impact compression-a porcine study. Journal of Orthopaedic Research, 27, 1100-1108.

Equine Tendon Tissue

Young,N.J., Becker,D.L., Fleck,R.A., Goodship,A.E. and Patterson-Kane,J.C. (2009) Maturational alterations in gap junction expression and associated collagen synthesis in response to tendon function. Matrix Biology, 28, 311-323.

Mouse Embryonic Fibroblast Cell Line (NIH 3T3)

Zhang,W., Rong,J., Wang,Q. and He,X. (2009) The encapsulation and intracellular delivery of trehalose using a thermally responsive nanocapsule. Nanotechnology, 20, 275101.

Mouse Model of Atopic Dermatitis

Zheng,T., Oh,M., Oh,S., Wu,F., Myers,A. and Zhu,Z. (2009) IL-13 Regulation of Skin Remodeling in a Mouse Model of Atopic Dermatitis. The Journal of Allergy and Clinical Immunology, 123, 35.

Murine Lung Tissue

Zhou,Y., Mohsenin,A., Morschl,E., Young,H.W.J., Molina,J.G., Ma,W., Sun,C.X., Martinez-Valdez,H. and Blackburn,M.R. (2009) Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A2B Adenosine Receptor. The Journal of Immunology, 182, 8037-8046.

2008

Mouse Model of Dermal Fibrosis

Akhmetshina,A., Dees,C., Pileckyte,M., Maurer,B., Axmann,R., Jungel,A., Zwerina,J., Gay,S., Schett,G. and Distler,O. (2008) Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis. The FASEB Journal, 22, 2214-2222.

Scleroderma Fibroblasts

Akhmetshina,A., Dees,C., Pileckyte,M., Szucs,G., Spriewald,B.M., Zwerina,J., Distler,O., Schett,G. and Distler,J.H. (2008) Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts. Arthritis Rheum, 58, 2553-2564.

Rabbit Bone Marrow Cells Seeded on Porcine Small Intestine Submucosa

Almarza,A.J., Yang,G., Woo,S.L.Y., Nguyen,T. and Abramowitch,S.D. (2008) Positive Changes in Bone Marrow-Derived Cells in Response to Culture on an Aligned Bioscaffold. Tissue Engineering, 14, 1489-1495.

Human Lung Fibroblasts

Antao-Menezes,A., Turpin,E.A., Bost,P.C., Ryman-Rasmussen,J.P. and Bonner,J.C. (2008) STAT-1 Signaling in Human Lung Fibroblasts Is Induced by Vanadium Pentoxide through an IFN-beta Autocrine Loop. The Journal of Immunology, 180, 4200-4207.

Cultured Human Intrahepatic (Myo) Fibroblasts (hIHFs)

Aoudjehane,L., Pissaia,A., Scatton,O., Podevin,P., Massault,P.P., Chouzenoux,S., Soubrane,O., Calmus,Y. and Conti,F. (2008) Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway. Laboratory Investigation, 88, 973-985.

Human Dermal Fibroblasts

Bhogal, R.K. and Bona, C.A. (2008) Regulatory Effect of Extracellular Signal- Regulated Kinases (ERK) on Type I Collagen Synthesis in Human Dermal Fibroblasts Stimulated by IL-4 and IL-13. International Reviews of Immunology, 27, 472 – 496.

Porcine Valvular Interstitial Cells from Various Regions of the Mitral Valve

Blevins,T.L., Peterson,S.B., Lee,E.L., Bailey,A.M., Frederick,J.D., Huynh,T.N., Gupta,V. and Grande-Allen,K. (2008) Mitral Valvular Interstitial Cells Demonstrate Regional, Adhesional, and Synthetic Heterogeneity. Cells Tissues Organs, 187, 113-122.

Human Lung Fibroblasts and Mouse Bleomycin Induced Lung Fibrosis

Borie,R., Fabre,A., Prost,F., Marchal-Somme,J., Lebtahi,R., Marchand-Adam,S., Aubier,M., Soler,P. and Crestani,B. (2008) Activation of somatostatin receptors attenuates pulmonary fibrosis. Thorax, 63, 251-258.

An Alloxan Rabbit Ear Ulcer Model

Breen,A.M., Dockery,P., O'Brien,T. and Pandit,A.S. (2008) The use of therapeutic gene eNOS delivered via a fibrin scaffold enhances wound healing in a compromised wound model. Biomaterials, 29, 3143-3151.

Polycarbonate Track-Etched Membranes

Bueno,E.M. and Ruberti,J.W. (2008) Optimizing collagen transport through track-etched nanopores. Journal of Membrane Science, 321, 250-263.

Human Lung Fibroblasts

Caraci,F., Gili,E., Calafiore,M., Failla,M., La Rosa,C., Crimi,N., Sortino,M.A., Nicoletti,F., Copani,A. and Vancheri,C. (2008) TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. Pharmacological Research, 57, 274-282.

Fetal Rat Lung Tissue

Chen,C.M., Chou,H.C., Wang,L.F. and Lang,Y.D. (2008) Experimental Oligohydramnios Decreases Collagen in Hypoplastic Fetal Rat Lungs. Experimental Biology and Medicine, 233, 1334-1340.

Rabbit Digitorum Extensor Tendon

Chen,C.H., Liu,H.W., Tsai,C.L., Yu,C.M. and Lin,I. (2008) Photoencapsulation of Bone Morphogenetic Protein-2 and Periosteal Progenitor Cells Improve Tendon Graft Healing in a Bone Tunnel. The American Journal of Sports Medicine, 36, 461-473.

Murine Osteoblastic MC3T3-E1 Cells

Choi,E.M. and Kim,Y.H. (2008) Hesperetin attenuates the highly reducing sugar-triggered inhibition of osteoblast differentiation. Cell Biology and Toxicology, 24, 225-231.

Bone Marrow Derived Mesenchymal Stem Cells (MSCs)

Choi,K.M., Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S. and Park,J.K. (2008) Effect of ascorbic acid on bone marrow-derived mesenchymal stem cell proliferation and differentiation. Journal of Bioscience and Bioengineering, 105, 586-594.

Rabbit Autologous Cells from Vaginal Biopsy

De Philippo,R.E., Bishop,C.E., Freitas Filho,L., Yoo,J.J. and Atala,A. (2008) Tissue Engineering a Complete Vaginal Replacement From a Small Biopsy of Autologous Tissue. Transplantation, 86, 208-214.

Human Fibroblasts from Systemic Sclerotic Patients

Distler,J.H.W., Akhmetshina,A., Schett,G. and Distler,O. (2008) Monocyte chemoattractant proteins in the pathogenesis of systemic sclerosis. Rheumatology, 48, 98-103.

Atherosclerotic Lesions in Apo-E-Deficient Mice

Do,G.M., Kwon,E.Y., Kim,H.J., Jeon,S.M., Ha,T.Y., Park,T. and Choi,M.S. (2008) Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice. Biochemical and Biophysical Research Communications, 374, 55-59.

Rat Lung Tissue

Elgrabli,D., bella-Gallart,S., Robidel,F., Rogerieux,F., Boczkowski,J. and Lacroix,G. (2008) Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes. Toxicology, 253, 131-136.

Murine Lung Tissue

Fabre,A., Marchal-Somme,J., Marchand-Adam,S., Quesnel,C., Borie,R., Dehoux,M., Ruffie,C., Callebert,J., Launay,J.M. and Henin,D. (2008) Modulation of bleomycin induced lung fibrosis by serotonin receptor antagonists in mice. European Respiratory Journal, doi:10.1183/09031936-00126907.

Murine Lung Tissue

Failla,M., Genovese,T., Mazzon,E., Fruciano,M., Fagone,E., Gili,E., Barera,A., La Rosa,C., Conte,E., Crimi,N., Cuzzocrea, S. and Vaneheri, C. (2008) 16, 16-Dimethyl Prostaglandin E2 Efficacy on Prevention and Protection from Bleomycin-induced Lung Injury and Fibrosis. American Journal of Respiratory Cell and Molecular Biology, doi:10.1165/rcmb.2007-04380C.

Mesenchymal Stem Cells

Fan,H., Liu,H., Toh,S.L. and Goh,J.C.H. (2008) Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. Biomaterials, 29, 1017-1027.

Mesenchymal Stem Cells and Silk Scaffold

Fan,H., Liu,H., Wong,E.J.W., Toh,S.L. and Goh,J.C.H. (2008) In vivo study of anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold. Biomaterials, 29, 3324-3337.

Murine Intestinal Myofibroblasts

Fichtner-Feigl,S., Young,C.A., Kitani,A., Geissler,E.K., Schlitt,H.J. and Strober,W. (2008) IL-13 Signaling via IL-13Ra2 Induces Major Downstream Fibrogenic Factors Mediating Fibrosis in Chronic TNBS Colitis. Gastroenterology, 135, 2003-2013.e7.

Bone Marrow Samples

Freyman, T. (2008) Decellularized bone marrow extracellular matrix. US Patent 7326571.

Cartilage Tissue

Furukawa,K.S., Imura,K., Tateishi,T. and Ushida,T. (2008) Scaffold-free cartilage by rotational culture for tissue engineering. Journal of Biotechnology, 133, 134-145.

Collagen Based Scaffolds

Garcia,Y., Wilkins,B., Collighan,R.J., Griffin,M. and Pandit,A. (2008) Towards development of a dermal rudiment for enhanced wound healing response. Biomaterials, 29, 857-868.

Hepatic Stellate Cells

Gardi,C., Arezzini,B., Monaco,B., De Montis,M.G., Vecchio,D. and Comporti,M. (2008) F 2-isoprostane receptors on hepatic stellate cells. Laboratory Investigation, 88, 124-131.

ECM Model of Fibroblast Monolayer and Endothelial Cell-Coated Beads

Ghajar,C.M., Chen,X., Harris,J.W., Suresh,V., Hughes,C.C.W., Jeon,N.L., Putnam,A.J. and George,S.C. (2008) The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis. Biophysical Journal, 94, 1930-1941.

Human Carotid Plaques

Gonçalves, I., Ares, M.P.S., Moberg, A., Moses, J., To, F., Montan, J., Pedro, L.M., Dias, N., e Fernandes, J.F., Fredrikson, G.N., Nilsson, J., Jovinge, S. and Bengtsson, E. (2008) Elastin- and Collagen-Rich Human Carotid Plaques Have Increased Levels of the Cysteine Protease Inhibitor Cystatin C. Journal of Vascular Research, 45, 395 – 401.

Murine Intestinal Tissue

Grassl,G.A., Valdez,Y., Bergstrom,K.S.B., Vallance,B.A. and Finlay,B.B. (2008) Chronic Enteric Salmonella Infection in Mice Leads to Severe and Persistent Intestinal Fibrosis. Gastroenterology, 134,768-780.e2.

293 T-Rex Cell Line

Greenspan,D., Zhang,Y. and GE,G. (2008) Method and composition for treating a fibrotic disorder. WIPO Patent Application WO/2008/024767.

Porcine Valvular Interstitial Cells from Distinct Regions of Mitral Valve

Gupta,V., Werdenberg,J.A., Mendez,J.S. and Jane Grande-Allen,K. (2008) Influence of strain on proteoglycan synthesis by valvular interstitial cells in three-dimensional culture. Acta Biomaterialia, 4, 88-96.

Porcine Valvular Interstitial Cells from Valve Leaflet and Chordae

Gupta,V., Werdenberg,J.A., Lawrence,B.D., Mendez,J.S., Stephens,E.H. and Grande-Allen,K.J. (2008) Reversible Secretion of Glycosaminoglycans and Proteoglycans by Cyclically Stretched Valvular Cells in 3D Culture. Annals of Biomedical Engineering, 36, 1092-1103.

Demineralized Bone Matrix

Han,B., Yang,Z. and Nimni,M. (2008) Effects of gamma irradiation on osteoinduction associated with demineralized bone matrix. Journal of Orthopaedic Research, 26, 75-82.

Murine Lung Tissue

Hardie,W.D., Davidson,C., Ikegami,M., Leikauf,G.D., Le Cras,T.D., Prestridge,A., Whitsett,J.A. and Korfhagen,T.R. (2008) EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-α-induced pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L1217-L1225.

Rabbit Fibrocartilaginous Tissues

Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2008) Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Research and Therapy, 8, R98.

Murine Lung Tissue

Hashimoto,S., Amaya,F., Matsuyama,H., Ueno,H., Kikuchi,S., Tanaka,M., Watanabe,Y., Ebina,M., Ishizaka,A. and Tsukita,S. (2008) Dysregulation of lung injury and repair in moesin-deficient mice treated with intratracheal bleomycin. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L566-L574.

Human Annulus Fibrosus (HAF) Cells

Helen,W. and Gough,J.E. (2008) Cell viability, proliferation and extracellular matrix production of human annulus fibrosus cells cultured within PDLLA/Bioglass® composite foam scaffolds in vitro. Acta Biomaterialia, 4, 230-243.

Murine Lung Tissue

Hirata,H., Arima,M., Fukushima,Y., Ishii,Y., Tokuhisa,T. and Fukuda,T. (2008) Effects of Th2 pulmonary inflammation in mice with bleomycin-induced pulmonary fibrosis. Respirology, 13, 788-798.

Murine Liver Tissue

Hisamori,S., Tabata,C., Kadokawa,Y., Okoshi,K., Tabata,R., Mori,A., Nagayama,S., Watanabe,G., Kubo,H. and Sakai,Y. (2008) All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production. Liver International, 28, 1217-1225.

Rat Mesenchymal Stem Cells and Porcine Aortic Valve Leaflets.

Hong,H., Dong,G.N., Shi,W.J., Chen,S., Guo,C. and Hu,P. (2008) Fabrication of Biomatrix/Polymer Hybrid Scaffold for Heart Valve Tissue Engineering in Vitro. ASAIO Journal, 54, 627-632.

Murine Dorsum

Hong,H.J., Jin,S.E., Park,J.S., Ahn,W.S. and Kim,C.K. (2008) Accelerated wound healing by smad3 antisense oligonucleotides-impregnated chitosan/alginate polyelectrolyte complex. Biomaterials, 29, 4831-4837.

Mouse Model of Scleroderma

Hoyles,R.K., Khan,K., Shiwen,X., Howat,S.L., Lindahl,G.E., Leoni,P., du Bois,R.M., Wells,A.U., Black,C.M. and Abraham,D.J. (2008) Fibroblast-Specific Perturbation of Transforming Growth Factor Signaling Provides Insight Into Potential Pathogenic Mechanisms of Scleroderma-Associated Lung Fibrosis. Arthritis & Rheumatism, 58, 1175-1188.

Mouse Cardiac Fibroblasts

Hu,C., Dandapat,A., Sun,L., Khan,J.A., Liu,Y., Hermonat,P.L. and Mehta,J.L. (2008) Regulation of TGF β1-mediated Collagen Formation by LOX-1: Studies Based on Forced Overexpression of TGF β1 in Wild-Type and LOX-1 Knock-Out Mouse Cardiac Fibroblasts. Journal of Biological Chemistry, 283, 10226-10231.

Human Cartilage Culture and a Rabbit Model of Osteoarthritis

Huh,J.E., Baek,Y.H., Ryu,S.R., Lee,J.D., Choi,D.Y. and Park,D.S. (2008) Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. International Immunopharmacology, 9, 230-240.

Osteoblasts In Vitro and Calvarial Osteoblasts In Vivo

Idris,A.I., Rojas,J., Greig,I.R., van’t Hof,R.J. and Ralston,S.H. (2008) Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro. Calcified Tissue International, 82, 191-201.

Murine Cardiac Tissue

Inagaki,K., Koyanagi,T., Berry,N.C., Sun,L. and Mochly-Rosen,D. (2008) Pharmacological Inhibition of ε-Protein Kinase C Attenuates Cardiac Fibrosis and Dysfunction in Hypertension-Induced Heart Failure. Hypertension, 51, 1565.

Human Periodontal Ligament Cell Line (HPL)

Inubushi,T., Tanaka,E., Rego,E.B., Kitagawa,M., Kawazoe,A., Ohta,A., Okada,H., Koolstra,J.H., Miyauchi,M. and Takata,T. (2008) Effects of Ultrasound on the proliferation and differentiation of Cementoblast lineage Cells. Journal of Periodontology, 79, 1-2.

Primary Hepatic Stellate Cells from Wild Type and Sept 4-/-Mice

Iwaisako,K., Hatano,E., Taura,K., Nakajima,A., Tada,M., Seo,S., Tamaki,N., Sato,F., Ikai,I. and Uemoto,S. (2008) Loss of Sept4 exacerbates liver fibrosis through the dysregulation of hepatic stellate cells. Journal of Hepatology, 49, 768-778.

Murine Lung Tissue

Kakizaki,T., Kohno,M., Watanabe,M., Tajima,A., Izumi,Y., Miyasho,T., Tasaka,S., Fukunaga,K., Maruyama,I. and Ishizaka,A. (2008) Exacerbation of Bleomycin-Induced Injury and Fibrosis by Pneumonectomy in the Residual Lung of Mice. Journal of Surgical Research, doi:10.1016/j.jss.2008.06.021.

Rat Renal Tissue and Cultured Mesangial Cells

Kang,Y.S., Ko,G.J., Lee,M.H., Song,H.K., Han,S.Y., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrology Dialysis Transplantation, doi:10.1093/ndt/gfn448.

Murine Skin

Kanno,Y., Kaneiwa,A., Minamida,M., Kanno,M., Tomogane,K., Takeuchi,K., Okada,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2008) The Absence of uPAR Is Associated with the Progression of Dermal Fibrosis. Journal of Investigative Dermatology, doi:10.1038/jid.2008.157.

Human Gingival Fibroblasts

Kim,J.Y., Park,S.H., Cho,K.S., Kim,H.J., Lee,C.K., Park,K.K., Choi,S.H. and Chung,W.Y. (2008) Mechanism of Azithromycin Treatment on Gingival Overgrowth. Journal of Dental Research, 87, 1075.

Mouse Primary and NIH/3T3 Fibroblasts

Kitowska,K., Zakrzewicz,D., Königshoff,M., Chrobak,I., Grimminger,F., Seeger,W., Bulau,P. and Eickelberg,O. (2008) Functional role and species-specific contribution of arginases in pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L34-L45.

Rat Renal Tissue and Cultured Mesangial Cells

Ko,G.J., Kang,Y.S., Han,S.Y., Lee,M.H., Song,H.K., Han,K.H., Kim,H.K., Han,J.Y. and Cha,D.R. (2008) Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrology Dialysis Transplantation, 23, 2750-2760.

Lung Epithelial Cells

Königshoff,M., Balsara,N., Pfaff,E.M., Kramer,M., Chrobak,I., Seeger,W. and Eickelberg,O. (2008) Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis. PLoS ONE, 3 (5) e2142.doi:1371/journal.pone.0002142.

Rat Bone Marrow-Derived Mesenchymal Stromal Cells (BMSCs)

Kwon,D.S., Gao,X., Liu,Y.B., Dulchavsky,D.S., Danyluk,A.L., Bansal,M., Chopp,M., McIntosh,K., Arbab,A.S. and Dulchavsky,S.A. (2008) Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats. International Wound Journal, 5, 453-463.

Mouse Osteoblastic MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2008) Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells. European Journal of Pharmacology, 591, 1-6.

Murine Lung Tissue

Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Lee,K.Y., Choe,Y.H., Hong,S.H., Lee,Y.R., Kim,J.S. and Hong,S.J. (2008) Inhibition of VEGF blocks TGF-β1 production through a PI3K/Akt signalling pathway. European Respiratory Journal, 31, 523-531.

Murine Tissue

Lee,S.J., Van Dyke,M., Atala,A. and Yoo,J.J. (2008) Host Cell Mobilization for In Situ Tissue Regeneration. Rejuvenation Research, 11, 747-756.

Murine Lung Tissue

Le Saux,O., Teeters,K., Miyasato,S., Choi,J., Nakamatsu,G., Richardson,J.A., Starcher,B., Davis,E.C., Tam,E.K. and Jourdan-Le Saux,C. (2008) The role of caveolin-1 in pulmonary matrix remodeling and mechanical properties. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L1007-L1017.

Renal Tissue of Zucker Diabetic Fatty Rats

Li,Y., Qi,Y., Kim,M.S., Xu,K.Z., Huang,T.H., Rong,X., Murray,M. and Yamahara,J. (2008) Increased renal collagen cross-linking and lipid accumulation in nephropathy of Zucker diabetic fatty rats. Diabetes Metab Res Rev., 24, 498-506.

Cardiac Fibroblasts

Lijnen,P., Petrov,V., van Pelt,J. and Fagard,R. (2008) Inhibition of Superoxide Dismutase Induces Collagen Production in Cardiac Fibroblasts. American Journal of Hypertension, 21, 1129-1136.

Human Lung Tissue from Patients with Idiopathic Pulmonary Fibrosis and Human Fibroblasts

Lin,L., Zhou,Z., Zheng,L., Alber,S., Watkins,S., Ray,P., Kaminski,N., Zhang,Y. and Morse,D. (2008) Cross Talk between Id1 and Its Interactive Protein Dril1 Mediate Fibroblast Responses to Transforming Growth Factor-β in Pulmonary Fibrosis. American Journal of Pathology, 173, 337-346.

Rat Hepatic Stellate Cell Line (HSC-T6)

Lin,Y.L., Wu,C.F. and Huang,Y.T. (2008) Effects of rhubarb on migration of rat hepatic stellate cells. Journal of Gastroenterology and Hepatology, doi:10.1111/j.1440-1746.2008.05573.x.

Osteoblasts

Liu,H., Yazici,H., Ergun,C., Webster,T.J. and Bermek,H. (2008) An in vitro evaluation of the Ca/P ratio for the cytocompatibility of nano-to-micron particulate calcium phosphates for bone regeneration. Acta Biomaterialia, 4, 1472-1479.

Normal Human Bronchial Epithelial Cells

Malavia,N.K., Mih,J.D., Raub,C.B., Dinh,B.T., George,S.C., Tirumurugaan,K.G., Kang,B.N., Panettieri,R.A., Foster,D.N. and Walseth,T.F. (2008) IL-13 induces a bronchial epithelial phenotype that is profibrotic. Respiratory Research, 9, 27.

Leiomyoma and Myometrial Cells

Malik,M., Webb,J. and Catherino,W.H. (2008) Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells. Clinical Endocrinology, 69, 462-470.

Rat Cardiomyocytes

Mancuso,P., Rahman,A., Hershey,S.D., Dandu,L., Nibbelink,K.A. and Simpson,R.U. (2008) 1, 25-Dihydroxyvitamin-D3 Treatment Reduces Cardiac Hypertrophy and Left Ventricular Diameter in Spontaneously Hypertensive Heart Failure-prone (cp/+) Rats Independent of Changes in Serum Leptin. Journal of Cardiovascular Pharmacology, 51, 559-564.

Murine Model of Plexiform Neurofibroma

McDaniel,A.S. (2008) The role of PAK1 in the cellular and molecular components of plexiform neurofibromas.

http://hdl.handle.net/1805/1696.

Human Lung Fibroblasts and Myofibroblasts

Milam,J.E., Keshamouni,V.G., Phan,S.H., Hu,B., Gangireddy,S.R., Hogaboam,C.M., Standiford,T.J., Thannickal,V.J. and Reddy,R.C. (2008) PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 294, L891-L901.

Human Retinal Pigment Epithelial (ARPE-19) Cell Line

Morales,S.A., Mareninov,S., Wadehra,M., Zhang,L., Goodglick,L., Braun,J. and Gordon,L.K. (2008) Epithelial Membrane Protein 2 (EMP2) Controls Collagen Gel Contraction in ARPE-19 Cells by Modulating FAK Activation. Investigative Ophthalmology & Visual Science, doi:10:1167/iovs.07-1598.

Murine Lung Tissue

Mozaffarian,A., Brewer,A.W., Trueblood,E.S., Luzina,I.G., Todd,N.W., Atamas,S.P. and Arnett,H.A. (2008) Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis. The Journal of Immunology, 181, 7243.

Human IPF/UIP Fibroblasts

Murray,L.A., Argentieri,R.L., Farrell,F.X., Bracht,M., Sheng,H., Whitaker,B., Beck,H., Tsui,P., Cochlin,K. and Evanoff,H.L. (2008) Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2. International Journal of Biochemistry and Cell Biology, 40, 2174-2182.

Human Lung Fibroblasts

Murray,L.A., Hackett,T.L., Warner,S.M., Shaheen,F., Argentieri,R.L., Dudas,P., Farrell,F.X. and Knight,D.A. (2008) BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis. PLoS ONE, 3,e4039.

Bovine Articular Cartilage

Natoli,R.M., Scott,C.C. and Athanasiou,K.A. (2008) Temporal Effects of Impact on Articular Cartilage Cell Death, Gene Expression, Matrix Biochemistry, and Biomechanics. Annals of Biomedical Engineering, 36, 780-792.

Murine Model of Liver Cirrhosis

Nishibe,Y., Kaneko,H., Suzuki,H., Abe,T., Matsuura,Y. and Takaku,H. (2008) Baculovirus-mediated interferon alleviates dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model. Gene Therapy, 15, 990-997.

Horse Superficial Digital Flexor Tendon

Nixon,A.J., Dahlgren,L.A., Haupt,J.L., Yeager,A.E. and Ward,D.L. (2008) Effect of adipose-derived nucleated cell fractions on tendon repair in horses with collagenase-induced tendinitis. American Journal of Veterinary Research, 69, 928-937.

Rat Mesenchymal Stem Cells

Ocarino,N.M., Boeloni,J.N., Goes,A.M., Silva,J.F., Marubayashi,U. and Serakides,R. (2008) Osteogenic differentiation of mesenchymal stem cells from osteopenic rats subjected to physical activity with and without nitric oxide synthase inhibition. Nitric Oxide, 19,320-325.

Murine Intestinal Tissue

Okoshi,K., Kubo,H., Nagayama,S., Tabata,C., Kadokawa,Y., Hisamori,S., Yonenaga,Y., Fujimoto,A., Mori,A. and Onodera,H. (2008) All-trans-Retinoic Acid Attenuates Radiation-Induced Intestinal Fibrosis in Mice. Journal of Surgical Research, 150, 53-59.

Normal Human Lung Fibroblast (NHLF) Cells

Pandey, A., Scarborough, R. M., and Venkatraman, M. S. (2008) Compositions and methods for inhibiting TGF-β. US Patent 7314939.

Human Dermal Fibroblasts

Park,H.J., Cho,D.H., Kim,H.J., Lee,J.Y., Cho,B.K., Bang,S.I., Song,S.Y., Yamasaki,K., Di Nardo,A. and Gallo,R.L. (2008) Collagen Synthesis Is Suppressed in Dermal Fibroblasts by the Human Antimicrobial Peptide LL-37. Journal of Investigative Dermatology, doi:10.1038/jid.2008.320.

Rabbit Mesenchymal Cells

Park,K.H. and Na,K. (2008) Effect of growth factors on chondrogenic differentiation of rabbit mesenchymal cells embedded in injectable hydrogels. Journal of Bioscience and Bioengineering, 106, 74-79.

Human Mesenchymal Stem Cells

Richardson,S.M., Hughes,N., Hunt,J.A., Freemont,A.J. and Hoyland,J.A. (2008) Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels. Biomaterials, 29, 85-93.

Normal Human Lung Fibroblast (NHLF) Cells

Scarborough, R. M., Pandey, A., and Mehrotra, M. (2008) Compositions and method for inhibiting TGF-β. US Patent 7361669.

Lacrimal Gland Extra Cellular Matrix from Healthy (BALB/C) and Diseased (NOD) Mice

Schenke-Layland,K., Xie,J., Angelis,E., Starcher,B., Wu,K., Riemann,I., MacLellan,W.R. and Hamm-Alvarez,S.F. (2008) Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome. Matrix Biology, 27, 53-66.

Human Anterior Cruciate Ligament Cell and T-Lymphocyte Cultures

Seo,Y.K., Yoon,H.H., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S. and Park,J.K. (2008) Increase in cell migration and angiogenesis in a composite silk scaffold for tissue-engineered ligaments. Journal of Orthopaedic Research: doi:1002/jor.20752.

Mouse Model of Dermal Fibrosis

Shibusawa,Y., Negishi,I., Tabata,Y. and Ishikawa,O. (2008) Mouse model of dermal fibrosis induced by one-time injection of bleomycin-poly (L-lactic acid) microspheres. Rheumatology, 47, 454-457.

Several Tumor Cell Lines

Shimazaki,M. and Kudo,A. (2008) Impaired capsule formation of tumors in periostin-null mice. Biochemical and Biophysical Research Communications, 367, 736-742.

Murine Lung Tissue

Shofer,S., Badea,C., Qi,Y., Potts,E., Foster,W.M. and Johnson,G.A. (2008) A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury. Journal of Applied Physiology, 105, 669-677.

Murine Lung Tissue

Shvedova,A.A., Kisin,E., Murray,A.R., Johnson,V.J., Gorelik,O., Arepalli,S., Hubbs,A.F., Mercer,R.R., Keohavong,P. and Sussman,N. (2008) Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. American Journal of Physiology- Lung Cellular and Molecular Physiology, 295, L552-L565.

Human Fibroblast Cultures from Healthy Patients and Patients with Systemic Sclerosis (SSC)

Skhirtladze,C., Distler,O., Dees,C., Akhmetshina,A., Busch,N., Venalis,P., Zwerina,J., Spriewald,B., Pileckyte,M. and Schett,G. (2008) Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis. Arthritis and Rheumatism, 58, 1475-1484.

Cultured Mesangial Cells

Song,H.K., Lee,M.H., Kim,B.K., Park,Y.G., Ko,G.J., Kang,Y.S., Han,J.Y., Han,S.Y., Han,K.H. and Kim,H.K. (2008) Visfatin: A New Player in Mesangial Cell Physiology and Diabetic Nephropathy. American Journal of Physiology- Renal Physiology, doi:10:1152/ajprenal.90231.2008.

Osteoblasts

Souza,D.M., Andrade,A.L., Fabris,J.D., Valério,P., Góes,A.M., Leite,M.F. and Domingues,R.Z. (2008) Synthesis and in vitro evaluation of toxicity of silica-coated magnetite nanoparticles. Journal of Non-Crystalline Solids, 354, 4894-4897.

Primary Cultures of Dermal Papilla Cells, Dermal Sheath Cells and Interfollicular Dermal Fibroblasts from Female Temporo-Occipital Scalp

Stevenson,S., Taylor,A.H., Meskiri,A., Sharpe,D.T. and Thornton,M.J. (2008) Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion. Wound Repair and Regeneration, 16, 243-253.

Dermis Extracellular Matrix

Sun,W.Q. and Leung,P. (2008) Calorimetric study of extracellular tissue matrix degradation and instability after gamma irradiation. Acta Biomaterialia, 4, 817-826.

Rat Pancreatic Stellate Cells and Rat Pancreatic Acinar Cells

Tahara,J., Shimizu,K. and Shiratori,K. (2008) Engulfment of Necrotic Acinar Cells by Pancreatic Stellate Cells Inhibits Pancreatic Fibrogenesis. Pancreas, 37, 69-74.

Murine Lung Tissue

Tourdot,S., Mathie,S., Hussell,T., Edwards,L., Wang,H., Openshaw,P.J.M., Schwarze,J. and Lloyd,C.M. (2008) Respiratory syncytial virus infection provokes airway remodelling in allergen-exposed mice in absence of prior allergen sensitization. Clinical & Experimental Allergy, 38, 1016-1024.

Murine Cardiac Tissue from Transgenic Mice

Ueno,M., Suzuki,J., Zenimaru,Y., Takahashi,S., Koizumi,T., Noriki,S., Yamaguchi,O., Otsu,K., Shen,W.J. and Kraemer,F.B. (2008) Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice. American Journal of Physiology- Endocrinology and Metabolism, 294, E1109-E1118.

Murine Lung Tissue

Walters, D.M. and Kleeberger, S.R. (2008) Mouse Models of Bleomycin-Induced Pulmonary Fibrosis. Current Protocols in Pharmacology, doi: 10.1002/0471141755.ph0546s40.

Murine Lung Tissue

Wang,C., Abe,S., Matsuda,K., Yu,C., Li,Y., Usuki,J., Azuma,A. and Kudoh,S. (2008) Effects of Gefitinib on Radiation-induced Lung Injury in Mice. Journal of Nippon Medical School, 75, 96-105.

Human Primary Lung Fibroblasts and Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis

Xia,H., Diebold,D., Nho,R., Perlman,D., Kleidon,J., Kahm,J., Avdulov,S., Peterson,M., Nerva,J. and Bitterman,P. (2008) Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis. Journal of Experimental Medicine, doi:10.1084/jem.20080001.

Murine Lung Tissue

Yamauchi,E., Shoji,S., Nishihara,M., Shimoda,T. and Nishima,S. (2008) Contribution of Lung Fibroblast Migration in the Fibrotic Process of Airway Remodelling in Asthma. Allergology International, 57, 73-78.

Canine Chondrocytes

Yanez,J.A., Remsberg,C.M., Vega-Villa,K.R., Miranda,N.D., Navas,J., Ohgami,Y., McCormick,D., Hughes,K., Temple,C. and Martinez,S.A. (2008) Pharmacological Evaluation of Glyco-Flex® III and its Constituents on Canine Chondrocytes. Journal of Medical Sciences, 8, 98-101.

Murine Lung Tissue

Zheng,T., Liu,W., Oh,S.Y., Zhu,Z., Hu,B., Homer,R.J., Cohn,L., Grusby,M.J. and Elias,J.A. (2008) IL-13 Receptor α2 Selectively Inhibits IL-13-Induced Responses in the Murine Lung. The Journal of Immunology, 180, 522-529.

Skin

Zheng,T., Oh,M.H., Oh,S.Y., Schroeder,J.T., Glick,A.B. and Zhu,Z. (2008) Transgenic Expression of Interleukin-13 in the Skin Induces a Pruritic Dermatitis and Skin Remodeling. Journal of Investigative Dermatology, doi:10.1038/jid.2008.295.

2007

Dermal Fibroblasts

Ahlfors,J.E.W. and Billiar,K.L. (2007) Biomechanical and biochemical characteristics of a human fibroblast-produced and remodeled matrix. Biomaterials, 28, 2183-2191.

Murine Vascular and Pulmonary Cells

Ambalavanan,N., LI,P., Bulger,A., Murphy-Ullrich,J., Oparil,S. and Chen,Y.F. (2007) Endothelin-1 Mediates Hypoxia-Induced Increases in Vascular Collagen in the Newborn Mouse Lung. Pediatr Res, 61, 559-564.

Murine Lung Tissue

Azuma,M., Nishioka,Y., Aono,Y., Inayama,M., Makino,H., Kishi,J., Shono,M., Kinoshita,K., Uehara,H., Ogushi,F., Izumi,K. and Sone,S. (2007) Role of alpha1-acid glycoprotein in therapeutic antifibrotic effects of imatinib with macrolides in mice. Am J Respir Crit Care Med., 176, 1243 – 1250.

Human Uterine Leiomyomas

Britten,J.L., Malik,M., Payson,M., Norian,J., Joseph,D. and Catherino,W.H. (2007) All-trans retinoic acid regulates collagen synthesis in human uterine leiomyomas. Fertility and Sterility, 88, 218.

Equine Tendon-Derived Fibrillar Collagen Constructs

Butler,L.M., Metson-Scott,T., Felix,J., Abhyankar,A., Rainger,G.E., Farndale,R.W., Watson,S.P. and Nash,G.B. (2007) Sequential adhesion of platelets and leukocytes from flowing whole blood onto a collagen-coated surface: Requirement for a GpVI-binding site in collagen. Thromb Haemost, 97, 814-821.

Rat Lung Tissue

Chen,C.M., Wang,L.F., Chou,H.C., Lang,Y.D. and Lai,Y.P. (2007) Up-regulation of Connective Tissue Growth Factor in Hyperoxia-Induced Lung Fibrosis. Pediatric Research, 62, 128 – 133.

Murine Osteoblastic MC3T3-E1 Cell Line

Choi,E.M. (2007) Modulatory effects of luteolin on osteoblastic function and inflammatory mediators in osteoblastic MC3T3-E1 cells. Cell Biology International, 31, 870-877.

Murine Osteoblastic MC3T3-E1 Cell Line

Choi,E.M. (2007) Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-α-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells. Pharmazie, 62, 216-220.

Human Mesenchymal Stem Cells

Choi,K.M., Yoon,H.H., Seo,Y.K., Song,K.Y., Kwon,S.Y., Lee,H.S., Park,Y.S., Kim,Y.J. and Park,J.K. (2007) Effect of essential and nonessential amino acid compositions on the in vitro behavior of human mesenchymal stem cells. Korean Journal of Chemical Engineering, 24, 1058-1063.

Murine Cardiac Fibroblasts

Colston,J.T., de la Rosa,S.D., Koehler,M., Gonzales,K., Mestril,R., Freeman,G.L., Bailey,S.R. and Chandrasekar,B. (2007) Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. American Journal of Physiology- Heart and Circulatory Physiology, 293, H1839.

Rat Hepatic Stellate Cells

Comporti,M., Signorini,C., Arezzini,B., Vecchio,D., Monaco,B. and Gardi,C. (2007) F2-isoprostanes are not just

markers of oxidative stress. Free Radical Biology and Medicine, 44, 247-256.

Mouse Lung Tissue

Denis,O., van den Brûle,S., Heymans,J., Havaux,X., Rochard,C., Huaux,F. and Huygen,K. (2007) Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling. Immunology, 122, 268-278.

Human Colonic Myofibroblasts

Di Sabatino,A., Pender,S.L.F., Jackson,C.L., Prothero,J.D., Gordon,J.N., Picariello,L., Rovedatti,L., Docena,G., Monteleone,G. and Rampton,D.S. (2007) Functional Modulation of Crohn’s Disease Myofibroblasts by Anti-Tumor Necrosis Factor Antibodies. Gastroenterology, 133, 137-149.

Human Dermal Fibroblasts

Digel,I., Kurulgan,E., Linder,P., Kayser,P., Porst,D., Braem,G.J., Zerlin,K., Artmann,G.M. and Artmann,A.T. (2007) Decrease in extracellular collagen crosslinking after NMR magnetic field application in skin fibroblasts. Medical and Biological Engineering and Computing, 45, 91-97.

Murine Muscle Samples

DuBay,D.A., Choi,W., Urbanchek,M.G., Wang,X., Adamson,B., Dennis,R.G., Kuzon Jr,W.M. and Franz,M.G. (2007) Incisional Herniation Induces Decreased Abdominal Wall Compliance via Oblique Muscle Atrophy and Fibrosis. Ann Surg, 245, 140-146.

Murine Kidney Samples

El Chaar,M., Chen,J., Seshan,S.V., Jha,S., Richardson,I., Ledbetter,S.R., Vaughan Jr,E.D., Poppas,D.P. and Felsen,D. (2007) Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction. American Journal of Physiology- Renal Physiology, 292, F1291-F1301.

Murine Lung Tissue

Faress,J.A., Nethery,D.E., Kern,E.F.O., Eisenberg,R., Jacono,F.J., Allen,C.L. and Kern,J.A. (2007) Bleomycin Induced Pulmonary Fibrosis is Attenuated by a Monoclonal Antibody Targeting HER2. Journal of Applied Physiology, 103, 2077-2083.

Murine Colon Samples

Fichtner-Feigl,S., Fuss,I.J., Young,C.A., Watanabe,T., Geissler,E.K., Schlitt,H.J., Kitani,A. and Strober,W. (2007) Induction of IL-13 Triggers TGF-beta1-Dependent Tissue Fibrosis in Chronic 2, 4, 6-Trinitrobenzene Sulfonic Acid Colitis. The Journal of Immunology, 178, 5859.

Leporine Mesenchymal Stem Cells

Hannouche,D., Terai,H., Fuchs,J.R., Terada,S., Zand,S., Nasseri,B.A., Petite,H., Sedel,L. and Vacanti,J.P. (2007) Engineering of implantable cartilaginous structures from bone marrow-derived mesenchymal stem cells. Tissue Eng. 13, 87-99.

Human Embryonic Stem Cells (hESCs) – Cell Lines H9 and BG01V

Hoben,G.M., Koay,E.J. and Athanasiou,K.A. (2007) Fibrochondrogenesis in Two Embryonic Stem Cell Lines: Effects of Differentiation Timelines. Stem Cells, 26, 422- 430.

Murine Liver Tissues

Hsu,Y.C., Chiu,Y.T., Cheng,C.C., Wu,C.F., Lin,Y.L. and Huang,Y.T. (2007) Antifibrotic effects of tetrandrine on hepatic stellate cells and rats with liver fibrosis. Journal of Gastroenterology and Hepatology, 22, 99-111.

Human Primary Keloid Fibroblast Culture Supernatant

Hsu,Y.C., Hsiao,M., Chien,Y.W. and Lee,W.R. (2007) Exogenous nitric oxide stimulated collagen type I expression and TGF-β1 production in keloid fibroblasts by a cGMP-dependent manner. Nitric Oxide, 16, 258-265.

Murine Pulmonary Lysates, Macrophage Cell Line RAW 264.7 and Human Normal Lung Fibroblast MRC-5 Cell Line

Hsu,Y.C., Wang,L.F. and Chien,Y.W. (2007) Nitric oxide in the pathogenesis of diffuse pulmonary fibrosis. Free Radical Biology and Medicine, 42, 599-607.

Human Primary Fibroblast Culture and Murine Dermal Tissue Samples

Huber,L.C., Distler,J.H., Moritz,F., Hemmatazad,H., Hauser,T., Michel,B.A., Gay,R.E., Matucci-Cerinic,M., Gay,S. and Distler,O. (2007) Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis. Arthritis Rheum, 56, 2755-2764.

Murine Bladder Tissue

Imamura,M., Kanematsu,A., Yamamoto,S., Kimura,Y., Kanatani,I., Ito,N., Tabata,Y. and Ogawa,O. (2007) Basic fibroblast growth factor modulates proliferation and collagen expression in urinary bladder smooth muscle cells. American Journal of Physiology- Renal Physiology, 293, F1007-F1017.

Dog Cardiovascular Tissue

Jugdutt,B.I., Idikio,H. and Uwiera,R.R.E. (2007) Angiotensin receptor blockade and angiotensin-converting-enzyme inhibition limit adverse remodeling of infarct zone collagens and global diastolic dysfunction during healing after reperfused ST-elevation myocardial infarction. Molecular and Cellular Biochemistry, 303, 27-38.

Murine Lung Tissue

Kai,Y., Yoneyama,H., Koyama,J., Hamada,K., Kimura,H. and Matsushima,K. (2007) Treatment with chondroitinase ABC alleviates bleomycin-induced pulmonary fibrosis. Medical Molecular Morphology, 40, 128-140.

Murine Pancreatic Stellate Cells

Kaku,T., Oono,T., Zhao,H., Gibo,J., Kawabe,K., Ito,T. and Takayanagi,R. (2007) IS-741 Attenuates Local Migration of Monocytes and Subsequent Pancreatic Fibrosis in Experimental Chronic Pancreatitis Induced by Dibutyltin Dichloride in Rats. Pancreas, 34, 299-309.

Murine Lung Homogenates

Kang,H.R., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) Semaphorin 7A plays a critical role in TGF-β1-induced pulmonary fibrosis. J. Exp. Med., 204, 1083.

Murine Lung Tissue

Kang,H.R., Cho,S.J., Lee,C.G., Homer,R.J. and Elias,J.A. (2007) TGF-beta 1 stimulates pulmonary fibrosis and inflammation via a bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12. Journal of Biological Chemistry, 282, 7723-7732.

Murine Lung Tissue

Kanno,Y., Kuroki,A., Okada,K., Tomogane,K., Ueshima,S., Matsuo,O. and Matsuno,H. (2007) α2-Antiplasmin is involved in the production of transforming growth factor β1 and fibrosis. Journal of Thrombosis and Haemostasis, 5, 2266-2273.

Human Stem Cells

Kim,S.G., Jeon,C.H., Suh,H., Choe,J.Y. and Shin,I.H. (2007) P-glycoprotein expression in extracellular matrix formation of chondrogenic differentiation of human adult stem cells. Cell Biology International, 31, 1042-1048.

Human Myocardial Samples

Klotz,S., Danser,A.H., Foronjy,R.F., Oz,M.C., Wang,J., Mancini,D., D'Armiento,J. and Burkhoff,D. (2007) The Impact of Angiotensin-Converting Enzyme Inhibitor Therapy on the Extracellular Collagen Matrix During Left Ventricular Assist Device Support in Patients With End-Stage Heart Failure. Journal of the American College of Cardiology, 49, 1166.

Murine Lung Tissue

Kohan, M., Bader,R., Puxeddu,I., Levi-Schaffer,F., Breuer,R. and Berkman,N. (2007) Enhanced osteopontin expression in a murine model of allergen-induced airway remodelling. Clinical & Experimental Allergy, 37, 1444-1454.

Ovine Mesenchymal Progenitor Cells

Kunisaki,S.M., Fuchs,J.R., Steigman,S.A. and Fauza,D.O. (2007) A comparative analysis of cartilage engineered from different perinatal mesenchymal progenitor cells. Tissue Eng. 13, 2633 – 2644.

Human Fibroblast Cell Lines

Lareu,R.R., Arsianti,I., Subramhanya,H.K., Yanxian,P., Raghunath,M. (2007) In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering; a preliminary study. Tissue Eng. 13, 385-391.

Murine Cementoblastic Cell Line, OCCM-30

La-Bona,D.A., Tanaka,E., Inubushi,T., Oka,H., Ohta,A., Okada,H., Miyauchi,M., Takata,T. and Tanne,K. (2007) Cementoblast response to low-and high-intensity ultrasound. Archives of Oral Biology, 53, 318-323.

Ovine Bone Marrow Mesenchymal Cells

Luo,Z.J. and Seedhom,B.B. (2007) Light and low-frequency pulsatile hydrostatic pressure enhances extracellular matrix formation by bone marrow mesenchymal cells: an in-vitro study with special reference to cartilage repair. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 221, 499-507.

Murine Lung Tissue

Maret,M., Ruffie,C., Periquet,B., Campo,A.M., Menevret,M., Phelep,A., Dziewiszek,K., Druilhe,A. and Pretolani,M. (2007) Liposomal Retinoic Acids Modulate Asthma Manifestations in Mice. Journal of Nutrition, 137, 2730 – 2736.

Murine Dermal Biopsies

Matsushita,T., Fujimoto,M., Hasegawa,M., Matsushita,Y., Komura,K., Ogawa,F., Watanabe,R., Takehara,K. and Sato,S. (2007) BAFF Antagonist Attenuates the Development of Skin Fibrosis in Tight-Skin Mice. Journal of Investigative Dermatology, 127, 2772-2780.

Murine Lung Tissue

Mishra,A., Wang,M., Schlotman,J., Nikolaidis,N.M., DeBrosse,C.W., Karow,M.L. and Rothenberg,M.E. (2007) Resistin-like molecule-beta is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung. American Journal of Physiology- Lung Cellular and Molecular Physiology, 293, L305.

Murine Lung Homogenates

Misson,P., Brombacher,F., Delos,M., Lison,D. and Huaux,F. (2007) Type 2 immune response associated with silicosis is not instrumental in the development of the disease. American Journal of Physiology- Lung Cellular and Molecular Physiology, 292, L107-L113.

Murine Bronchoalveolar Lavage Fluid

Morschl,E., Volmer,J.B., Molina,J.G., Lee,J.J., Ochkur,S.I. and Blackburn,M.R. (2007) A3 Adenosine Receptors Modulate Eosinophil Function In Bleomycin-Induced Lung Injury. The Journal of Allergy and Clinical Immunology, 119, 218.

Murine Fibroblast NIH3T3 Cell Line

Nishi,Y., Sano,H., Kawashima,T., Okada,T., Kuroda,T., Kikkawa,K., Kawashima,S., Tanabe,M., Goto,T. and Matsuzawa,Y. (2007) Role of Galectin-3 in Human Pulmonary Fibrosis. Allergology International, 1, 57-65.

Murine Lung Tissue

Niu,N., Le Goff,M.K., Li,F., Rahman,M., Homer,R.J. and Cohn,L. (2007) A Novel Pathway That Regulates Inflammatory Disease in the Respiratory Tract. The Journal of Immunology, 178, 3846.

Murine Pancreatic Stellate Cells

Nomiyama,Y., Tashiro,M., Yamaguchi,T., Watanabe,S., Taguchi,M., Asaumi,H., Nakamura,H. and Otsuki,M. (2007) High Glucose Activates Rat Pancreatic Stellate Cells Through Protein Kinase C and p38 Mitogen-Activated Protein Kinase Pathway. Pancreas, 34, 364-372.

Human Epithelial Cells

Ornatowski,W., Poschet,J.F., Perkett,E., Taylor-Cousar,J.L. and Deretic,V. (2007) Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A induced cytotoxicity. Journal of Clinical Investigation, 117, 3489.

Murine Primary Osteoblasts

Orriss,I.R., Utting,J.C., Brandao-Burch,A., Colston,K., Grubb,B.R., Burnstock,G. and Arnett,T.R. (2007) Extracellular Nucleotides Block Bone Mineralization in Vitro: Evidence for Dual Inhibitory Mechanisms Involving Both P2Y2 Receptors and Pyrophosphate. Endocrinology, 148, 4208.

Murine Pulmonary Tissue

Pena,A.M., Fabre,A., Débarre,D., Marchal-Somme,J., Crestani,B., Martin,J.L., Beaurepaire,E. and Schanne-Klein,M.C. (2007) Three-dimensional investigation and scoring of extracellular matrix remodeling during lung fibrosis using multiphoton microscopy. Microsc.Res.Tech. 70, 162 – 170.

Murine Lung Tissue

Pilling,D., Roife,D., Wang,M., Ronkainen,S.D., Crawford,J.R., Travis,E.L. and Gomer,R.H. (2007) Reduction of Bleomycin-Induced Pulmonary Fibrosis by Serum Amyloid P. The Journal of Immunology, 179, 4035.

Human Primary Fetal and Postnatal Dermal Fibroblasts

Rolfe,K., Grobbelaar,A.O. and Linge,C. (2007) Is TGF-B1 signalling active in fetuses? Journal of Plastic, Reconstructive & Aesthetic Surgery, 60, S11.

Human Fetal and Postnatal Fibroblasts

Rolfe,K.J., Richardson,J., Vigor,C., Irvine,L.M., Grobbelaar,A.O. and Linge,C. (2007) A Role for TGF-bold italic beta 1-Induced Cellular Responses during Wound Healing of the Non-Scarring Early Human Fetus? Journal of Investigative Dermatology, 127, 2656-2667.

Ovine Blood-Derived Endothelial Progenitor Cells

Sales,V.L., Engelmayr Jr,G.C., Johnson Jr,J.A., Gao,J., Wang,Y., Sacks,M.S. and Mayer Jr,J.E. (2007) Protein Precoating of Elastomeric Tissue-Engineering Scaffolds Increased Cellularity, Enhanced Extracellular Matrix Protein Production, and Differentially Regulated the Phenotypes of Circulating Endothelial Progenitor Cells. Circulation, 116, 155-163.

Rat Choloangiocytes

Sato,Y., Harada,K., Ozaki,S., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ikeda,H., Sasaki,M. and Nakanuma,Y. (2007) Cholangiocytes with Mesenchymal Features Contribute to Progressive Hepatic Fibrosis of the Polycystic Kidney Rat. American Journal of Pathology, 171, 1859 – 1871.

Equine Flexor Digitorum Superficialis Tendon (SDFT) Explants

Schnabel,L.V., Mohammed,H.O., Miller,B.J., McDermott,W.G., Jacobson,M.S., Santangelo,K.S. and Fortier,L.A. (2007) Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons. J Orthop Res, 25, 230-240.

Murine Lung Tissue

Shvedova,A.A., Kisin,E.R., Murray,A.R., Gorelik,O., Arepalli,S., Castranova,V., Young,S.H., Gao,F., Tyurina,Y.Y., Oury,T.D. and Kagan,V.E. (2007) Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. Toxicology and Applied Pharmacology, 221, 339-348.

Murine Lung Homogenate

Swain,S.D., Han,S., Harmsen,A., Shampeny,K. and Harmsen,A.G. (2007) Pulmonary Hypertension Can Be a Sequela of Prior Pneumocystis Pneumonia. American Journal of Pathology, 171, 790-799.

Murine Sponge Implants

Tkalcević,V.I., Cuzić,S., Brajsa,K., Mildner,B., Bokulić,A., Situm,K., Perović,D., Glojnarić,I. and Parnham,M.J. (2007) Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expression. European Journal of Pharmacology, 570, 212-221.

Murine Lung Homogenate

Vittal,R., Zhang,H., Han,M.L.K., Moore,B.B., Horowitz,J.C. and Thannickal,V.J. (2007) Effects of the Protein Kinase Inhibitor, Imatinib Mesylate, on Epithelial/Mesenchymal Phenotypes: Implications for Treatment of Fibrotic Diseases. Journal of Pharmacology and Experimental Therapeutics, 321, 35-44.

Murine Lung Tissue

Wallach-Dayan,S.B., Golan-Gerstl,R. and Breuer,R. (2007) Evasion of myofibroblasts from immune surveillance: A mechanism for tissue fibrosis. Proceedings of the National Academy of Sciences, 104, 20460.

Leporine Chondrocyte

Xie,J.U.N., Han,Z., Kim,S.O.O.H., Kim,Y.H.A. and Takehisa Matsuda,P.D. (2007) Mechanical Loading-Dependence of mRNA Expressions of Extracellular Matrices of Chondrocytes Inoculated into Elastomeric Microporous Poly (L-lactide-co-e-caprolactone) Scaffold. Tissue Engineering, 13, 29-40.

Bovine Decellularised Vocal Fold Lamina and Human Vocal Fold Fibroblast Primary Culture

Xu,C.C., Chan,R.W. and Tirunagari,N. (2007) A Biodegradable, Acellular Xenogeneic Scaffold for Regeneration of the Vocal Fold Lamina Propria. Tissue Engineering, 13, 551-566.

Murine Dermal Biopsy

Yamamoto,T., Yokozeki,H. and Nishioka,K. (2007) Fas-and FasL-deficient mice are resistant to the induction of bleomycin-induced scleroderma. Archives of Dermatological Research, 298, 465-468.

Murine Dermal Tissue

Yoshioka,T., Imura,K., Hikita,I., Hirasawa,T., Sakata,T., Matsutani,T., Horikawa,T. and Arimura,A. (2007) Impact of T-cell receptor V haplotypes on the development of dermatitis in DS-Nh mice: synergistic production of interleukin-13 caused by staphylococcal enterotoxin C and peptide glycans from Staphylococcus aureus. Immunology, 121, 51-61.

Murine Lung Tissue

Young,L.R., Pasula,R., Gulleman,P.M., Deutsch,G.H. and McCormack,F.X. (2007) Susceptibility of Hermansky-Pudlak Mice to Bleomycin-Induced Type II Cell Apoptosis and Fibrosis. Am J Respir Cell Mol Biol, 37 67 – 74.

2006

Murine Pacreatic Stellate Cells

Asaumi,H., Watanabe,S., Taguchi,M., Tashiro,M., Nagashio,Y., Nomiyama,Y., Nakamura,H. and Otsuki,M. (2006) Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits ethanol-induced activation of pancreatic stellate cells. European Journal of Clinical Investigation, 36, 113-122.

Leporine cartilage and Chondrocyte Explants

Baek,Y.H., Huh,J.E., Lee,J.D., Choi,D.Y. and Park,D.S. (2006) Effect of Aralia cordata Extracts on Cartilage Protection and Apoptosis Inhibition. Biological & Pharmaceutical Bulletin, 29, 1423-1430.

Porcine Aortic Valves

Balachandran,K., Konduri,S., Sucosky,P., Jo,H. and Yoganathan,A.P. (2006) An Ex Vivo Study of the Biological Properties of Porcine Aortic Valves in Response to Circumferential Cyclic Stretch. Annals of Biomedical Engineering, 34, 1655-1665.

Human Articular Chondrocytes

Banu,N., Tsuchiya,T. and Sawada,R. (2006) Effects of a biodegradable polymer synthesized with inorganic tin on the chondrogenesis of human articular chondrocytes. J Biomed Mater Res A. 77, 84-89.

Murine Collagen Deposition on Polypropylene Tapes

Bogusiewicz,M., Wrobel,A., Jankiewicz,K., Adamiak,A., Skorupski,P., Tomaszewski,J. and Rechberger,T. (2006) Collagen deposition around polypropylene tapes implanted in the rectus fascia of female rats. European Journal of Obstetrics & Gynecology and Reproductive Biology, 124, 106-109.

Human Ventricular Tissue Samples

Bruggink,A.H., van Oosterhout,M.F.M., de Jonge,N., Ivangh,B., van Kuik,J., Voorbij,R.H.A.M., Cleutjens,J.P.M., Gmelig-Meyling,F.H.J. and de Weger,R.A. (2006) Reverse Remodeling of the Myocardial Extracellular Matrix After Prolonged Left Ventricular Assist Device Support Follows a Biphasic Pattern. Journal of Heart and Lung Transplantation, 25, 1091-1098.

Human Dermal Fibroblasts

Chan,E.S.L., Fernandez,P., Merchant,A.A., Montesinos,M.C., Trzaska,S., Desai,A., Tung,C.F., Khoa,D.N., Pillinger,M.H. and Reiss,A.B. (2006) Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma. Arthritis & Rheumatism, 54, 2632-2642.

Murine Lung Samples

Cho,S.J., Kang,M.J., Homer,R.J., Kang,H.R., Zhang,X., Lee,P.J., Elias,J.A. and Lee,C.G. (2006) Role of Early Growth Response-1 (Egr-1) in Interleukin-13-induced Inflammation and Remodeling. Journal of Biological Chemistry, 281, 8161.

Leporine Articular Cartilage

Cho,Y.J., Huh,J.E., Kim,D.Y., Kim,N.J., Lee,J.D., Baek,Y.H., Cho,E.M., Yang,H.R., Choi,D.Y. and Park,D.S. (2006) Effect of Betula platyphylla var. japonica on Proteoglycan Release, Type II Collagen Degradation, and Matrix Metalloproteinase Expression in Rabbit Articular Cartilage Explants. Biological & Pharmaceutical Bulletin, 29, 1408-1413.

Murine Hepatic Stellate Cells HSC-T6 and Liver Samples

Chong,L.W., Hsu,Y.C., Chiu,Y.T., Yang,K.C. and Huang,Y.T. (2006) Anti-Fibrotic Effects of Thalidomide on Hepatic Stellate Cells and Dimethylnitrosamine-Intoxicated Rats. Journal of Biomedical Science, 13, 403-418.

Murine Liver Tissue

Chou,W-Y., Lu,C-n., Lee,T-h., Wu,C-l., Hung,K-s., Concejero,A.M., Jawan,B. and Wang,C-h. (2006) Electroporative interleukin-10 gene transfer ameliorates carbon tetrachlo-ride-induced murine liver fibrosis by MMP and TIMP modulation. Acta Pharmacologica Sinica 27, 469-476.

Murine Bronchial Lavages

Chunn,J.L., Mohsenin,A., Young,H.W.J., Lee,C.G., Elias,J.A., Kellems,R.E. and Blackburn,M.R. (2006) Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations. American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 579-587.

Human Dermal Fibroblasts

Distler,J.H., Jüngel,A., Caretto,D., Schulze-Horsel,U., Kowal-Bielecka,O., Gay,R.E., Michel,B.A., Müller-Ladner,U., Kalden,J.R., Gay,S. and Distler,O. (2006) Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells. Arthritis Rheum, 54, 214-225.

Human Dermal Fibroblasts

Distler,J.H., Jüngel,A., Huber,L.C., Schulze-Horsel,U., Zwerina,J., Gay,R.E., Michel,B.A., Hauser,T., Schett,G. and Gay,S. (2006) Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum, 56, 311-322.

Murine Abdominal Wall Samples

DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and Franz,M.G. (2006) Mesh incisional herniorrhaphy increases abdominal wall elastic properties: A mechanism for decreased hernia recurrences in comparison with suture repair. Surgery, 140, 14-24.

Human Normal and Keloid Fibroblasts

Duong,H.S., Zhang,Q.Z., Le,A.D., Kelly,A.P., Kamdar,R. and Messadi,D.V. (2006) Elevated prolidase activity in keloids: correlation with type I collagen turnover. Br J Dermatol 154, 820-828.

Ovine Bone Marrow-Derived Mesenchymal Stem Cells

Engelmayr Jr,G.C., Sales,V.L., Mayer Jr,J.E. and Sacks,M.S. (2006) Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues. Biomaterials, 27, 6083-6095.

Murine Lung Samples

Fichtner-Feigl,S., Strober,W., Kawakami,K., Puri,R.K. and Kitani,A. (2006) IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β production and fibrosis. Nature Medicine, 12, 99-106.

Murine Bronchoalveolar Lavage Fluid

Fujimoto, H., Gabazza, E. C., Taguchi, O., Nishii, Y., Nakahara, H., Bruno, N. E., Alessandro-Gabazza, C. N., Kasper, M., Yano, Y., and Nagashima, M. (2006) Thrombin-Activatable Fibrinolysis Inhibitor Deficiency Attenuates Bleomycin-Induced Lung Fibrosis. American Journal of Pathology 168, 1086-1096.

Porcine Aortic Smooth Muscle Cells

Gavish,L., Perez,L. and Gertz,S.D. (2006) Low-level laser irradiation modulates matrix metalloproteinase activity and gene expression in porcine aortic smooth muscle cells. Lasers Surg Med., 38, 779-786.

Porcine Bone Marrow Stromal Cells

Goh,J.C.H., Te Tay,P.D. and Sl Toh,P.D. (2006) Characterization of a Novel Polymeric Scaffold for Potential Application in Tendon/Ligament Tissue Engineering. Tissue Engineering, 12, 91-99.

Murine Mesangial and Proximal Tubular Cell Culture Supernatants

Han,K.H., Kang,Y.S., Han,S.Y., Jee,Y.H., Lee,M.H., Han,J.Y., Kim,H.K., Kim,Y.S. and Cha,D.R. (2006) Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats. Kidney International, 70, 111-120.

Human Kidney-2 Cell Culture Supernatants

Han,S.Y., Jee,Y.H., Han,K.H., Kang,Y.S., Kim,H.K., Han,J.Y., Kim,Y.S. and Cha,D.R. (2006) An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy. Nephrology Dialysis Transplantation, 21, 2406.

Human Keratinocyte and Fibroblast Artificial Dermis

Harrison,C.A., Gossiel,F., Layton,C.M., Bullock,A.J., Johnson,T., Ubrey Blumsohn,P.D. and Sheila Macneil,P.D. (2006) Use of an in Vitro Model of Tissue-Engineered Skin to Investigate the Mechanism of Skin Graft Contraction. Tissue Engineering, 12, 3119-3113.

Leporine Temporomandibular Joint Disc Fibrocartilage, Knee Meniscus Fibrocartilage, Knee Articular Cartilage and Pubic Symphysis

Hashem,G., Zhang,Q., Hayami,T., Chen,J., Wang,W. and Kapila,S. (2006) Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss. Arthritis Res Ther., 8, R98.

Equine Superficial Digital Flexor Tendon in Explant Culture

Haupt,JL., Donnelly,BP. and Nixon,AJ. (2006) Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explants culture. Am J Vet Res, 67, 1595-1600.

Human Osteoblast-Like SaOS-2 Cell Line

Huh,J.E., Yang,H.R., Park,D.S., Choi,D.Y., Baek,Y.H., Cho,E.M., Cho,Y.J., Kang-Il,K., Kim,D.Y. and Lee,J.D. (2006) Puerariae radix promotes differentiation and mineralization in human osteoblast-like SaOS-2 cells. J Ethnopharmacol, 104, 345-350.

Murine Pulmonary Myofibroblasts

Izumi,N., Mizuguchi,S., Inagaki,Y., Saika,S., Kawada,N., Nakajima,Y., Inoue,K., Suehiro,S., Friedman,S.L. and Ikeda,K. (2006) BMP-7 opposes TGF-β1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2. American Journal of Physiology- Lung Cellular and Molecular Physiology, 290, 120-126.

Murine Lung Homogenates

Jacono,F.J., Peng,Y.J., Nethery,D., Faress,J.A., Lee,Z., Kern,J.A. and Prabhakar,N.R. (2006) Acute lung injury augments hypoxic ventilatory response in the absence of systemic hypoxemia. Journal of Applied Physiology, 101, 1795.

Human Gingival Fibroblasts

Kato,T., Okahashi,N., Ohno,T., Inaba,H., Kawai,S. and Amano,A. (2006) Effect of phenytoin on collagen accumulation by human gingival fibroblasts exposed to TNF-ain vitro. Oral Diseases, 12, 156-162.

Human Alveolar Epithelial (A549) and Akata Cell Lines

Keating,D.T., Sadlier,D.M., Patricelli,A., Smith,S.M., Walls,D., Egan,J.J. and Doran,P.P. (2006) Microarray identifies ADAM family members as key responders to TGF-beta 1 in alveolar epithelial cells. Respiratory Research, 7, 114.

Murine Kidneys

Kellner,D., Chen,J., Richardson,I., Seshan,S.V., EL Chaar,M., Vaughan Jr,E.D., Poppas,D. and Felsen,D. (2006) Angiotensin receptor blockade decreases fibrosis and fibroblast expression in a rat model of unilateral ureteral obstruction. J Urol, 176, 806-812.

Murine Kidney Cortex

Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2006) Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-beta type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds. J Control Release, 110, 610-617.

Murine Tracheal Homogenates

Lama,V.N., Harada,H., Badri,L.N., Flint,A., Hogaboam,C.M., McKenzie,A., Martinez,F.J., Toews,G.B., Moore,B.B. and Pinsky,D.J. (2006) Obligatory Role for Interleukin-13 in Obstructive Lesion Development in Airway Allografts. American Journal of Pathology, 169, 47.

Human ER-Positive Breast Cancer MCF-7 Cell Line and Murine Osteoblast-Like MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2006) Stimulatory effects of extract prepared from the bark of Cinnamomum cassia blume on the function of osteoblastic MC3T3-E1 cells. Phytother.Res, 20, 952-960.

Murine Osteoblast-Like MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2006) Rubus coreanus Miq. Extract Promotes Osteoblast Differentiation and Inhibits Bone-Resorbing Mediators in MC3T3-E1 Cells. The American Journal of Chinese Medicine, 34, 643-654.

Murine Lung Homogenate

Lee,K.S., Park,S.J., Kim,S.R., Min,K.H., Jin,S.M., Lee,H.K. and Lee,Y.C. (2006) Modulation of Airway Remodeling and Airway Inflammation by Peroxisome Proliferator-Activated Receptor γ in a Murine Model of Toluene Diisocyanate-Induced Asthma. The Journal of Immunology, 177, 5248.

Murine Liver Tissue

Lee,T.H., Jawan,B., Chou,W.Y., Lu,C.N., Wu,C.L., Kuo,H.M., Concejero,A.M. and Wang,C.H. (2006) alpha-Melanocyte-stimulating hormone gene therapy reverses carbon tetrachloride induced liver fibrosis in mice. J Gene Med, 8, 764-772.

Human Dermal Fibroblasts

Lee,J.H., Roh,M.R. and Lee,K.H. (2006) Effects of Infrared Radiation on Skin Photo-Aging and Pigmentation. Yonsei Med J., 47, 485-490.

Murine Bone Marrow Stromal Cells and Osteoblasts

Leivo,J., Meretoja,V., Vippola,M., Levanen,E., Vallittu,P. and Mantyla,T.A. (2006) Sol-gel derived aluminosilicate coatings on alumina as substrate for osteoblasts. Acta Biomater. 2, 659-668.

Human Skin Fibroblasts

Li,B., Chen,J. and James,H.C.W. (2006) RGD peptide-conjugated poly (dimethylsiloxane) promotes adhesion, proliferation, and collagen secretion of human fibroblasts. Mater Res, 79, 989-998.

Murine Cardiac Fibroblasts

Lijnen,P., Papparella,I., Petrov,V., Semplicini,A. and Fagard,R. (2006) Angiotensin II-stimulated collagen production in cardiac fibroblasts is mediated by reactive oxygen species. J Hypertens, 24, 757-766.

Murine Hepatocytes and Hepatic Stellate Cells

Lin,Y.L., Wu,C.H., Luo,M.H., Huang,Y.J., Wang,C.N., Shiao,M.S. and Huang,Y.T. (2006) In vitro protective effects of salvianolic acid B on primary hepatocytes and hepatic stellate cells. Journal of Ethnopharmacology, 105, 215-222.

Murine Lung Tissue

Liu,H., Liu,L., Fletcher,B.S. and Visner,G.A. (2006) Sleeping Beauty-based gene therapy with indoleamine 2, 3-dioxygenase inhibits lung allograft fibrosis. The FASEB Journal, 20, 2384.

Murine Lung Tissue

Lopez,E., del Pozo,V., Miguel,T., Sastre,B., Seoane,C., Civantos,E., Llanes,E., Baeza,M.L., Palomino,P. and Cardaba,B. (2006) Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine Model 1. The Journal of Immunology, 176, 1943-1950.

Murine Lung Tissue

Ma,B., Blackburn,M.R., Lee,C.G., Homer,R.J., Liu,W., Flavell,R.A., Boyden,L., Lifton,R.P., Sun,C.X. and Young,H.W. (2006) Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. Journal of Clinical Investigation, 116, 1274-1283.

Human Dermal Fibroblast Primary and CRL-2127 Cell Cultures

Makareeva,E., Cabral,W.A., Marini,J.C. and Leikin,S. (2006) Molecular Mechanism of Alpha 1(I)-Osteogenesis Imperfecta/Ehlers-Danlos Syndrome: Unfolding of an N-Anchor Domain at the N-Terminal End of the Type I Collagen Triple Helix. Journal of Biological Chemistry, 281, 6463.

Murine Lung Tissue

Manoury,B., Nenan,S., Guenon,I., Boichot,E., Planquois,J.M., Bertrand,C.P. and Lagente,V. (2006) Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice. J Inflamm (Lond), 3, 2.

Murine Dermal Tissue

McFarlin,K., Gao,X., Liu,Y.B., Dulchavsky,D.S., Kwon,D., Arbab,A.S., Bansal,M., Li,Y., Chopp,M. and Dulchavsky,S.A. (2006) Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat. Wound Repair and Regeneration, 14, 471-478.

Leporine Bone Marrow-Derived Mesenchymal Stem Cells

Medrado,G.C.B., Machado,C.B., Valerio,P., Sanches,M.D. and Goes,A.M. (2006) The effect of a chitosan-gelatin matrix and dexamethasone on the behavior of rabbit mesenchymal stem cells. Biomedical Materials, 1, 155-161.

Murine Rectal Tissue

Motomura,Y., Khan,W.I., El-Sharkawy,R.T., Verma-Gandhu,M., Verdu,E.F., Gauldie,J. and Collins,S.M. (2006) Induction of a fibrogenic response in mouse colon by overexpression of monocyte chemoattractant protein 1. Gut, 55, 662-670.

Human Lung Fibroblastic Cell Line TIG-3-20

Nagano, J., Iyonaga, K., Kawamura, K., Yamashita, A., Ichiyasu, H., Okamoto, T., Suga, M., Sasaki, Y., and Kohrogi, H. (2006) Use of tacrolimus, a potent antifibrotic agent, in bleomycin-induced lung fibrosis. European Respiratory Journal, 27, 460-469.

Murine Osteoblast-Like MC3T3-E1 Cell Line

Narita,Y., Nomura,J., Ohta,S., Inoh,Y., Suzuki,K.M., Araki,Y., Okada,S., Matsumoto,I., Isohama,Y. and Abe,K. (2006) Royal Jelly Stimulates Bone Formation: Physiologic and Nutrigenomic Studies with Mice and Cell Lines. Bioscience, Biotechnology, and Biochemistry, 70, 2508-2514.

Murine Lung Tissue

Oikonomou,N., Harokopos,V., Zalevsky,J., Valavanis,C., Kotanidou,A., Szymkowski,D.E., Kollias,G. and Aidinis,V. (2006) Soluble TNF Mediates the Transition from Pulmonary Inflammation to Fibrosis. PLoS ONE, 1, e108.

Murine Osteoblast Primay Cultures

Oktar,F.N., Valério,P., Goller,G., Agathopoulos,S., Goes,A.M. and Leite,M.F. (2006) Biocompatibility of the Outer Prismatic and the Inner Nacreous Layers of Four Different Molluscs. Key Engineering Materials, 309, 449.

Human Ligament Fibroblasts Primary Culture

Park,S.A., Kim,I.A., Lee,Y.J., Shin,J.W., Kim,C.R., Kim,J.K., Yang,Y.I. and Shin,J.W. (2006) Biological Responses of Ligament Fibroblasts and Gene Expression Profiling on Micropatterned Silicone Substrates Subjected to Mechanical Stimuli. Journal of Bioscience and Bioengineering, 102, 402-412.

Murine Hepatic Stellate Cells

Patella,S., Phillips,D.J., Tchongue,J., de Kretser,D.M. and Sievert,W. (2006) Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis. American Journal of Physiology- Gastrointestinal and Liver Physiology, 290, 137-144.

Human Fibroblast HFL-1 and Epithelial A549 Cell Line Co-Cultures

Phillips,R.J., Blatt,L.M. and Ozes,O.N. (2006) Pirfenidone and Interferon Gamma-1b Inhibit the Profibrotic Effects of Osteopontin. Chest, 130, 229S.

Murine Lung Tissue

Polte,T., Foell,J., Werner,C., Hoymann,H.G., Braun,A., Burdach,S., Mittler,R.S. and Hansen,G. (2006) CD137-mediated immunotherapy for allergic asthma. Journal of Clinical Investigation, 116, 1025-1036.

Human Mesenchymal Populations and Articular Chondrocytes

Pound,J.C., Green,D.W., Chaudhuri,J.B., Mann,S., Roach,H.I. and Oreffo,R.O.C. (2006) Strategies to Promote Chondrogenesis and Osteogenesis from Human Bone Marrow Cells and Articular Chondrocytes Encapsulated in Polysaccharide Templates. Tissue Engineerig, 12, 2789-2799.

Murine Cardiac Tissue

Reyes,M., Steinhelper,M.E., Alvarez,J.A., Escobedo,D., Pearce,J., Valvano,J.W., Pollock,B.H., Wei,C.L., Kottam,A. and Altman,D. (2006) Impact of physiological variables and genetic background on myocardial frequency-resistivity relations in the intact beating murine heart. American Journal of Physiology- Heart and Circulatory Physiology, 291, H1659.

Murine Fibroblast and Macrophage Co-Cultures

Saika, S., Ikeda, K., Yamanaka, O., Flanders, K. C., Okada, Y., Miyamoto, T., Kitano, A., Ooshima, A., Nakajima, Y., and Ohnishi, Y. (2006) Loss of Tumor Necrosis Factor α Potentiates Transforming Growth Factor β-mediated Pathogenic Tissue Response During Wound Healing. American Journal of Pathology 168, 1848-1860.

Ovine Blood-Derived Endothelial Progenitor Cells

Sales,V.L., Engelmayr Jr,G.C., Mettler,B.A., Johnson Jr,J.A., Sacks,M.S. and Mayer Jr,J.E. (2006) Transforming Growth Factor-β1 Modulates Extracellular Matrix Production, Proliferation, and Apoptosis of Endothelial Progenitor Cells in Tissue-Engineering Scaffolds. Circulation, 114, 1193-1199.

Murine Liver Tissue

Sato,Y., Harada,K., Furubo,S., Kizawa,K., Sanzen,T., Yasoshima,M., Ozaki,S., Isse,K., Sasaki,M. and Nakanuma,Y. (2006) Inhibition of Intrahepatic Bile Duct Dilation of the Polycystic Kidney Rat with a Novel Tyrosine Kinase Inhibitor Gefitinib. American Journal of Pathology, 169, 1238.

Porcine Cardiac Valve Leaflets

Schenke-Layland, K., Madershahian, N., Riemann, I., Starcher, B., Halbhuber, K. J., Konig, K., and Stock, U. A. Impact of Cryopreservation on Extracellular Matrix Structures of Heart Valve Leaflets. The Annals of Thoracic Surgery 81, 918-926.

Human Primary Fibroblast Cultures from Scleroderma Patients

Sherriff-Tadano,R., Ohta,A., Morito,F., Mitamura,M., Haruta,Y., Koarada,S., Tada,Y., Nagasawa,K. and Ozaki,I. (2006) Antifibrotic effects of hepatocyte growth factor on scleroderma fibroblasts and analysis of its mechanism. Modern Rheumatology, 16, 364-371.

Murine Lung Tissue

Shim,Y.M., Zhu,Z., Zheng,T., Lee,C.G., Homer,R.J., Ma,B. and Elias,J.A. (2006) Role of 5-Lipoxygenase in IL-13-Induced Pulmonary Inflammation and Remodeling. The Journal of Immunology, 177, 1918.

Porcine Heart Valves

Stock,U.A., Degenkolbe,I., Attmann,T., Schenke-Layland,K., Freitag,S. and Lutter,G. (2006) Prevention of device-related tissue damage during percutaneous deployment of tissue-engineered heart valves. The Journal of Thoracic and Cardiovascular Surgery, 131, 1323-1330.

Murine Lung Tissue and Bronchoalveolar Lavage Fluid

Sun,C.X., Zhong,H., Mohsenin,A., Morschl,E., Chunn,J.L., Molina,J.G., Belardinelli,L., Zeng,D. and Blackburn,M.R. (2006) Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury. Journal of Clinical Investigation, 116, 2173-2182.

Human Tendon Fibroblasts

Talwalkar,S.C., Evans,C.E., Trail,I.A. and McGrouther,D.A. (2006) Does Anatomical Location of a Tendon (Hand or Forearm) Influences Fibroblast Function in the Presence of Physical Forces. Journal of Bone and Joint Surgery – British Volume 88-B Supp. III:411.

Murine Lung Homogenate

Volmer,J.B., Thompson,L.F. and Blackburn,M.R. (2006) Ecto-5'-Nucleotidase (CD73)-Mediated Adenosine Production Is Tissue Protective in a Model of Bleomycin-Induced Lung Injury. The Journal of Immunology, 176, 4449-4458.

Murine Liver Tissue

Wang,C.H., Lee,T.H., Lu,C.N., Chou,W.Y., Hung,K.S., Concejero,A.M. and Jawan,B. (2006) Electroporative alpha-MSH gene transfer attenuates thioacetamide-induced murine hepatic fibrosis by MMP and TIMP modulation. Gene Therapy, 13, 1000-1009.

Bovine Annulus Fibrosus Primary Cell Culture

Wilda,H. and Gough,J.E. (2006) In vitro studies of annulus fibrosus disc cell attachment, differentiation and matrix production on PDLLA/45S5 Bioglass composite films. Biomaterials, 27, 5220-5229.

Murine Dermal Biopsy

Wu,G.L.D.M. and Varga,J. (2006) Increased Bleomycin-Induced Skin Fibrosis in Mice Lacking the Th1-Specific Transcription Factor T-bet. Pathobiology, 73, 224-237.

Murine Dermal Tissue

Yasuoka,H., Jukic,D.M., Zhou,Z., Choi,A.M. and Feghali-Bostwick,C.A. (2006) Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis. Arthritis Rheum, 54, 3001-3010.

2005

Murine Lung Explant

Aono,Y., Nishioka,Y., Inayama,M., Ugai,M., Kishi,J., Uehara,H., Izumi,K. and Sone,S. (2005) Imatinib as a Novel Antifibrotic Agent in Bleomycin-induced Pulmonary Fibrosis in Mice. American Journal of Respiratory and Critical Care Medicine, 171, 1279.

Murine Lung Explants

Azuma,A., Li,Y.J., Abe,S., Usuki,J., Matsuda,K., Henmi,S., Miyauchi,Y., Ueda,K., Izawa,A. and Sone,S. (2005) Interferon-β Inhibits Bleomycin-Induced Lung Fibrosis by Decreasing Transforming Growth Factor-β and Thrombospondin. American Journal of Respiratory Cell and Molecular Biology, 32, 93-98.

Murine Lung Explants

Barbarin,V., Xing,Z., Delos,M., Lison,D. and Huaux,F. (2005) Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles. American Journal of Physiology- Lung Cellular and Molecular Physiology, 288, 841-848.

Murine Lung Explants

Beamer,C.A. and Holian,A. (2005) Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure. American Journal of Physiology- Lung Cellular and Molecular Physiology, 289, 186-195.

Murine Lung Homogenates

Burdick,M.D., Murray,L.A., Keane,M.P., Xue,Y.Y., Zisman,D.A., Belperio,J.A. and Strieter,R.M. (2005) CXCL11 Attenuates Bleomycin-induced Pulmonary Fibrosis via Inhibition of Vascular Remodeling. American Journal of Respiratory and Critical Care Medicine, 171, 261.

Human Fibroblasts

Cabral,W.A., Makareeva,E., Colige,A., Letocha,A.D., Ty,J.M., Yeowell,H.N., Pals,G., Leikin,S. and Marini,J.C. (2005) Mutations Near Amino End of alpha 1(I) Collagen Cause Combined Osteogenesis Imperfecta/Ehlers-Danlos Syndrome by Interference with N-propeptide Processing. Journal of Biological Chemistry, 280, 19259-19269.

Human to Mouse Cardiac Allografts

Campbell,L.G., Ramachandran,S., Liu,W., Shipley,J.M., Itohara,S., Rogers,J.G., Moazami,N., Senior,R.M. and Jaramillo,A. (2005) Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection. Am J Transplant, 5, 517-528.

Human Dental Pulp Cells

Chan,C.P., Lan,W.H., Chang,M.C., Chen,Y.J., Lan,W.C., Chang,H.H. and Jeng,J.H. (2005) Effects of TGF-βs on the growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro. Archives of Oral Biology, 50, 469-479.

Murine Lung Homogenate

Chen,Q., Rabach,L., Noble,P., Zheng,T., Lee,C.G., Homer,R.J. and Elias,J.A. (2005) IL-11 Receptor a in the Pathogenesis of IL-13-Induced Inflammation and Remodeling 1. The Journal of Immunology, 174, 2305-2313.

Human Periodontal Fibroblasts

Chen,Y.J., Jeng,J.H., Jane Yao,C.C., Chen,M.H., Hou,L.T. and Lan,W.H. (2005) Long-term effect of pulsed Nd: YAG laser irradiation on cultured human periodontal fibroblasts. Lasers in Surgery and Medicine, 36, 225-233.

Murine Osteoblastic MC3T3-E1 Cell Line

Choi,E.M. (2005) The licorice root derived isoflavan glabridin increases the function of osteoblastic MC3T3-E1 cells. Biochem Pharmacol, 70, 363-368.

Murine Lung Homogenates

Chunn,J.L., Molina,J.G., Mi,T., Xia,Y., Kellems,R.E. and Blackburn,M.R. (2005) Adenosine-Dependent Pulmonary Fibrosis in Adenosine Deaminase-Deficient Mice 1. The Journal of Immunology, 175, 1937-1946.

Murine Hepatic Stellate Cells

Comporti,M., Arezzini,B., Signorini,C., Sgherri,C., Monaco,B. and Gardi,C. (2005) F2-isoprostanes stimulate collagen synthesis in activated hepatic stellate cells: a link with liver fibrosis?’ Laboratory Investigation, 85, 1381-1391.

Equine Tendons

Dahlgren,L., Mohammed,H. and Nixon,A. (2005) Temporal expression of growth factors and matrix molecules in healing tendon lesions. Journal of Orthopaedic Research, 23, 84-92.

Murine Thrombi

Deatrick,K.B., Eliason,J.L., Lynch,E.M., Moore,A.J., Dewyer,N.A., Varma,M.R., Pearce,C.G., Upchurch,G.R., Wakefield,T.W. and Henke,P.K. (2005) Vein wall remodeling after deep vein thrombosis involves matrix metalloproteinases and late fibrosis in a mouse model. J Vasc Surg, 42, 140-148.

Murine Abdominal Wall Samples

DuBay,D.A., Wang,X., Adamson,B., Kuzon,W.M., Dennis,R.G. and FRANZ,M.G. (2005) Progressive fascial wound failure impairs subsequent abdominal wall repairs: A new animal model of incisional hernia formation. Surgery, 137, 463-471.

Simian Renal Fibroblasts (NRK-49F)

El Chaar,M., Attia,E., Chen,J., Hannafin,J., Poppas,D.P. and Felsen,D. (2005) Cyclooxygenase-2 Inhibitor Decreases Extracellular Matrix Synthesis in Stretched Renal Fibroblasts. Nephron Exp Nephrol, 100, 150-155.

Ovine Vascular Smooth Muscle Cells

Engelmayr,G.C., Mayer,J.E., Rabkin,E., Sacks,M.S., Schoen,F.J. and Sutherland,F.W.H. (2005) The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials, 26, 175-187.

Murine Colon Homogenate

Fichtner-Feigl,S., Fuss,I.J., Preiss,J.C., Strober,W. and Kitani,A. (2005) Treatment of murine Th1-and Th2-mediated inflammatory bowel disease with NF-κB decoy oligonucleotides. Journal of Clinical Investigation, 115, 3057-3071.

Ovine Mesenchymal Progenitor Cells and Fetal Chondrocytes

Fuchs, J. R., Hannouche, D., Terada, S., Zand, S., Vacanti, J. P., and Fauza, D. O. (2005) Cartilage Engineering from Ovine Umbilical Cord Blood Mesenchymal Progenitor Cells. Stem Cells 23, 958-964.

Murine Fibroblasts and Mesenchymal Stem Cells

Ge,Z., Goh,J.C.H. and Lee,E.H. (2005) Selection of Cell Source for Ligament Tissue Engineering. Cell Transplantation, 14, 573-583.

Murine Lung Biopsies

Genovese,T., Cuzzocrea,S., Di Paola,R., Failla,M., Mazzon,E., Sortino,M.A., Frasca,G., Gili,E., Crimi,N. and Caputi,A.P. (2005) Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir Res, 6, 58.

Porcine Anterior Cruciate Ligaments

Harrison,R.D. (2005) Effect of Extraction Protocols and Epidermal Growth Factor on the Cellular Repopulaton of Decellularized Anterior Cruciate Ligament Allografts. Biomed Mater Res A,75, 841-854.

Murine Hepatic Stellate cells (HSC-T6) and Liver Samples

Hsu,Y.C., Lin,Y.L., Chiu,Y.T., Shiao,M.S., Lee,C.Y. and Huang,Y.T. (2005) Antifibrotic effects of Salvia miltiorrhiza on dimethylnitrosamine-intoxicated rats. Journal of Biomedical Science, 12, 185-195.

Rat Left Ventricle

Iwata,K., Sawa,Y., Kitagawa-Sakakida,S., Kawaguchi,N., Matsuura,N., Nakamura,T. and Matsuda,H. (2005) Gene transfection of hepatocyte growth factor attenuates the progression of cardiac remodeling in the hypertrophied heart. The Journal of Thoracic and Cardiovascular Surgery, 130, 719-725.

Human Gingival Fibroblasts

Kato,T., Okahashi,N., Kawai,S., Kato,T., Inaba,H., Morisaki,I. and Amano,A. (2005) Impaired Degradation of Matrix Collagen in Human Gingival Fibroblasts by the Antiepileptic Drug Phenytoin. J Periodontol, 76, 941-950.

Human Periodontal Ligament Cell Cultures

Kawase,T., Okuda,K., Saito,Y. and Yoshie,H. (2005) In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. J Periodontol, 76, 760-767.

Cadaveric Human Lumbar Intervertebral Discs

Keshari,K.R., Lotz,J.C., Kurhanewicz,J. and Majumdar,S. (2005) Correlation of HR-MAS Spectroscopy Derived Metabolite Concentrations With Collagen and Proteoglycan Levels and Thompson Grade in the Degenerative Disc. Spine, 30, 2683-2688.

Human Myocardial Samples

Klotz, S., Foronjy, R. F., Dickstein, M. L., Gu, A., Garrelds, I. M., Jan Danser, A. H., Oz, M. C., D'Armiento, J., and Burkhoff, D. (2005) Mechanical Unloading During Left Ventricular Assist Device Support Increases Left Ventricular Collagen Cross-Linking and Myocardial Stiffness. Circulation 112, 364-374.

Porcine Aortic Valves in Culture

Konduri,S., Xing,Y., Warnock,J.N., He,Z. and Yoganathan,A.P. (2005) Normal Physiological Conditions Maintain the Biological Characteristics of Porcine Aortic Heart Valves: An Ex Vivo Organ Culture Study. Annals of Biomedical Engineering, 33, 1158-1166.

Murine Kidney Cortex

Kushibiki,T., Nagata-Nakajima,N., Sugai,M., Shimizu,A. and Tabata,Y. (2005) Delivery of plasmid DNA expressing small interference RNA for TGF-beta type II receptor by cationized gelatin to prevent interstitial renal fibrosis. J Control Release, 105, 318-331.

Murine Dermal Fibroblasts

Lateef,H., Aslam,M.N., Stevens,M.J. and Varani,J. (2005) Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds. Archives of Dermatological Research, 297, 75-83.

Murine Granulomas

Layland,L.E., Wagner,H. and Prazeres da Costa,C. (2005) Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/-mice. Eur.J.Immunol, 35, 3248-3257.

Human Ligament Fibroblasts

Lee,C.H., Shin,H.J., Cho,I.H., Kang,Y.M., Kim,I.A., Park,K.D. and Shin,J.W. (2005) Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials, 26, 1261-1270.

Murine Osteoblast-Like MC3T3-E1 Cell Line

Lee,K.H. and Choi,E.M. (2005) Biochanin A Stimulates Osteoblastic Differentiation and Inhibits Hydrogen Peroxide-Induced Production of Inflammatory Mediators in MC3T3-E1 Cells. Biological & Pharmaceutical Bulletin, 28, 1948-1953.

Murine Lung Tissue Supernatant

Liu,H., Drew,P., Gaugler,A.C., Cheng,Y. and Visner,G.A. (2005) Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway. Am J Transplant, 5, 1256-1263.

Murine Dermal Biopsies

Matsushita,M., Yamamoto,T. and Nishioka,K. (2005) Plasminogen activator inhibitor-1 is elevated, but not essential, in the development of bleomycin-induced murine scleroderma. Clinical and Experimental Immunology, 139, 429-438.

Human Venous Myofibroblasts

Mol,A., van Lieshout,M.I., Dam-de Veen,C.G., Neuenschwander,S., Hoerstrup,S.P., Baaijens,F.P. and Bouten,C.V.C. (2005) Fibrin as a cell carrier in cardiovascular tissue engineering applications. Biomaterials, 26, 3113-3121.

Murine Lung Homogenate

Moore,B.B., Ballinger,M.N., White,E.S., Green,M.E., Herrygers,A.B., Wilke,C.A., Toews,G.B. and Peters-Golden,M. (2005) Bleomycin-Induced E Prostanoid Receptor Changes Alter Fibroblast Responses to Prostaglandin E2 1. The Journal of Immunology, 174, 5644-5649.

Cricetine Left Ventricles

Nakamura,T., Matsumoto,K., Mizuno,S., Sawa,Y., Matsuda,H. and Nakamura,T. (2005) Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts. American Journal of Physiology- Heart and Circulatory Physiology, 288, 2131-2139.

Human Lung Fibroblast Culture Supernatants

Nakoman,C., Resmi,H., Ay,O., Acikel,U., Atabey,N. and Güner,G. (2005) Effects of basic fibroblast factor (bFGF) on MMP-2, TIMP-2, and type-I collagen levels in human lung carcinoma fibroblasts. Biochimie, 87, 343-351.

Leporine Temporomandibular Joint Discs

Naqvi,T., Duong,T.T., Hashem,G., Shiga,M., Zhang,Q. and Kapila,S. (2005) Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants. Arthritis Res Ther, 7, R1-11.

Murine Lung Homogenate

Nethery,D.E., Moore,B.B., Minowada,G., Carroll,J., Faress,J.A. and Kern,J.A. (2005) Expression of mutant human epidermal receptor 3 attenuates lung fibrosis and improves survival in mice. Journal of Applied Physiology, 99, 298-307.

Human Atheromatous Plaques

Penz, S., Reininger, A. J., Brandl, R., Goyal, P., Rabie, T., Bernlochner, I., Rother, E., Goetz, C., Engelmann, B., and Smethurst, P. A. (2005) Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. The FASEB Journal 19, 898-909. 2005.

Porcine Chordae Tendineae

Ritchie, J., Warnock, J. N., and Yoganathan, A. P. (2005) Structural Characterization of the Chordae Tendineae in Native Porcine Mitral Valves. The Annals of Thoracic Surgery 80, 189-197.

Murine Osteoblast Primary Cultures

Sampaio,B.V., Göller,G., Oktar,F.N., Val rio,P., Goes,A.M. and Leite,M.F. (2005) Biocompatibility Evaluation of Three Different Titanium-Hydroxyapatite Composites. Key Eng.Mater, 284, 639-642.

Murine Dermal Biopsies

Santiago,B., Gutierrez-Cañas,I., Dotor,J., Palao,G., Lasarte,J.J., Ruiz,J., Prieto,J., Borrbs-Cuesta,F., Pablos,J.L. and Biotech,D. (2005) Topical Application of a Peptide Inhibitor of Transforming Growth Factor-bold beta 1 Ameliorates Bleomycin-Induced Skin Fibrosis. Journal of Investigative Dermatology, 125, 450-455.

Murine Osteoblast Primary Cultures

Schainberg,APM., Özyeğin,LS., Kursuoğlu,P., Valério,P., Goes,AM. and Leite,MF. (2005) Biocompatibility evaluation of Zeolite compared to bone HA, calcium phosphate (Ca2PO4) and Eugenol Paste. Key Engineering Materials 284-286, 561-564.

Murine Lung Tissue

Strieter,R.M., Keane,M.P., Burdick,M.D., Sakkour,A., Murray,L.A. and Belperio,J.A. (2005) The role of CXCR2/CXCR2 ligands in acute lung injury. Curr.Drug Targets Inflamm.Allergy, 4, 299-303.

Human Hepatic Stellate LI90 Cell Line

Sugimoto,R., Enjoji,M., Nakamuta,M., Ohta,S., Kohjima,M., Fukushima,M., Kuniyoshi,M., Arimura,E., Morizono,S. and Kotoh,K. (2005) Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cells. Liver International, 25, 420-428.

Ovine Fetal and Adult Chondrocytes

Terada,S., Fuchs,J.R., Yoshimoto,H., Fauza,D.O. and Vacanti,J.P. (2005) In Vitro Cartilage Regeneration From Proliferated Adult Elastic Chondrocytes. Annals of Plastic Surgery, 55, 196-201.

Ovine Chondrocytes

Terada,S., Yoshimoto,H., Fuchs,J.R., Sato,M., Pomerantseva,I., Selig,M.K., Hannouche,D. and Vacanti,J.P. (2005) Hydrogel optimization for cultured elastic chondrocytes seeded onto a polyglycolic acid scaffold. J.Biomed.Mater.Res.75A, 907-916.

Murine Osteoblast Primary Culture

Valério,P., Guimarbes,M.H.R., Pereira,M.M., Leite,M.F. and Goes,A.M. (2005) Primary osteoblast cell response to sol-gel derived bioactive glass foams. Journal of Materials Science: Materials in Medicine, 16, 851-856.

Human Fibroblast Primary Culture

Vancheri,C., Gili,E., Failla,M., Mastruzzo,C., Salinaro,E.T., LoFurno,D., Pistorio,M.P., La Rosa,C., Caruso,M. and Crimi,N. (2005) Bradykinin differentiates human lung fibroblasts to a myofibroblast phenotype via the B2 receptor. The Journal of Allergy and Clinical Immunology, 116, 1242-1248.

Murine Lung Homogenate

Vittal, R., Horowitz, J. C., Moore, B. B., Zhang, H., Martinez, F. J., Toews, G. B., Standiford, T. J., and Thannickal, V. J. (2005) Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury. American Journal of Pathology 166, 367-375.

Canine Arterial Tissue

Yamaguchi-Okada,M., Nishizawa,S., Koide,M. and Nonaka,Y. (2005) Biomechanical and phenotypic changes in the vasospastic canine basilar artery after subarachnoid hemorrhage. Journal of Applied Physiology, 99, 2045-2052.

Murine Pancreatic Tissue

Yoo,B.M., Yeo,M., Oh,T.Y., Choi,J.H., Kim,W.W., Kim,J.H., Cho,S.W., Kim,S.J. and Hahm,K.B. (2005) Amelioration of pancreatic fibrosis in mice with defective TGF-beta signaling. Pancreas, 30, e71-e79.

Murine Pancreatic Tissue

Yoo,B.M., Oh,T.Y., Kim,Y.B., Yeo,M., Lee,J.S., Surh,Y.J., Ahn,B.O., Kim,W.H., Sohn,S. and Kim,J.H. (2005) Novel Antioxidant Ameliorates the Fibrosis and Inflammation of Cerulein-Induced Chronic Pancreatitis in a Mouse Model. Pancreatology, 5, 165-176.

Murine Hepatic Stellate Cells

Zhou,Y-j., Yin,D-m., Chen,H-s., Shi,J-h., Sha,B-x. and Wang,X. (2005) Inhibitory effects of idoxifene on hepatic fibrosis in rats. Acta Pharmacologia Sinica, 26, 581-586.

2004

Murine Lung Homogenate

Barbarin, V., Arras, M., Misson, P., Delos, M., McGarry, B., Phan, S. H., Lison, D., and Huaux, F. (2004) Characterization of the Effect of Interleukin-10 on Silica-Induced Lung Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology 31, 78-85. 299.

Murine Lung Homogenates

Belperio,J.A., Dy,M., Murray,L., Burdick,M.D., Xue,Y.Y., Strieter,R.M. and Keane,M.P. (2004) The Role of the Th2 CC Chemokine Ligand CCL17 in Pulmonary Fibrosis 1. The Journal of Immunology, 173, 4692-4698.

Human Lung Tissue Samples and Murine Lung Homogenates

Berman,J.S., Serlin,D., Li,X., Whitley,G., Hayes,J., Rishikof,D.C., Ricupero,D.A., Liaw,L., Goetschkes,M. and O'Regan,A.W. (2004) Altered bleomycin-induced lung fibrosis in osteopontin-deficient mice. American Journal of Physiology- Lung Cellular and Molecular Physiology, 286, 1311-1318.

Murine Mammary Carcinoma MCa Cell Line

Casarsa,C., Mischis,M.T. and Sava,G. (2004) TGFbeta1 regulation and collagen-release-independent connective tissue re-modelling by the ruthenium complex NAMI-A in solid tumours. Journal of Inorganic Biochemistry, 98, 1648-1654.

Murine Lung Samples

Cho,J. (2004) ISS inhibits expression of MMP-9 and MMP-2 in a mouse model of airway remodeling. The Journal of Allergy and Clinical Immunology, 113, 92.

Human Patellar Tendon Fibroblasts

Cilli,F., Khan,M., Fu,F. and Wang,J.H. (2004) Prostaglandin E2 affects proliferation and collagen synthesis by human patellar tendon fibroblasts. Clin J Sport Med, 14, 232-236.

Human Pediatric Aortic Cells

Fu,P., Sodian,R., Luders,C., Lemke,T., Kraemer,L., Hubler,M., Weng,Y., Hoerstrup,S.P., Meyer,R. and Hetzer,R. (2004) Effects of basic fibroblast growth factor and transforming growth factor-beta on maturation of human pediatric aortic cell culture for tissue engineering of cardiovascular structures. ASAIO J, 50, 9-14.

Murine Bronchoalveolar Lavage Fluid

Hattori, N., Mizuno, S., Yoshida, Y., Chin, K., Mishima, M., Sisson, T. H., Simon, R. H., Nakamura, T., and Miyake, M. (2004) The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism. American Journal of Pathology, 164, 1091-1098.

Murine Lung Samples

Honda,K., Marquillies,P., Capron,M. and Dombrowicz,D. (2004) Peroxisome proliferator-activated receptor γ is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. The Journal of Allergy and Clinical Immunology, 113, 882-888.

Murine Liver Tissues

Hsu,Y.C., Chiu,Y.T., Lee,C.Y., Lin,Y.L. and Huang,Y.T. (2004) Increases in fibrosis-related gene transcripts in livers of dimethylnitrosamine-intoxicated rats. Journal of Biomedical Science, 11, 408-417.

Murine Periodontal Ligament Cells

Inoue,M., LeGeros,R.Z., Hoffman,C., Diamond,K., Rosenberg,P.A. and Craig,R.G. (2004) Effect of enamel matrix proteins on the phenotype expression of periodontal ligament cells cultured on dental materials. Journal of Biomedical Materials Research, 69, 172-179.

Murine Osteoblast-like (MC3T3-E1) and Odontoblast-like (MDPC23) Cell Lines

Inoue,M., LeGeros,R.Z., Inoue,M., Tsujigiwa,H., Nagatsuka,H., Yamamoto,T. and Nagai,N. (2004) In vitro response of osteoblast-like and odontoblast-like cells to unsubstituted and substituted apatites. Journal of Biomedical Materials Research, 70, 585-593.

Murine Lung Homogenates

Kolodsick,J.E., Toews,G.B., Jakubzick,C., Hogaboam,C., Moore,T.A., McKenzie,A., Wilke,C.A., Chrisman,C.J. and Moore,B.B. (2004) Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts 1. The Journal of Immunology, 172, 4068-4076.

Murine Hepatic Stellate Cells and Liver Tissue and Human Hepatic Stellate (TWNT-4) Cell Line

Kotoh,K., Nakamuta,M., Kohjima,M., Fukushima,M., Morizono,S., Kobayashi,N., Enjoji,M. and Nawata,H. (2004) Arg-Gly-Asp (RGD) peptide ameliorates carbon tetrachloride-induced liver fibrosis via inhibition of collagen production and acceleration of collagenase activity. Int J Mol Med, 14, 1049-1053.

Human Fibroblast (NHDF) Cell Line

Koya-Miyata,S., Okamoto,I., Ushio,S., Iwaki,K., Ikeda,M. and Kurimoto,M. (2004) Identification of a Collagen Production-promoting Factor from an Extract of Royal Jelly and Its Possible Mechanism. Bioscience, Biotechnology, and Biochemistry, 68, 767-773.

Human Dermal Biopsy

Lateef, H., Stevens, M. J., and Varani, J. (2004) All-trans-Retinoic Acid Suppresses Matrix Metalloproteinase Activity and Increases Collagen Synthesis in Diabetic Human Skin in Organ Culture. American Journal of Pathology 165, 167-174.

Human and Murine Bone Marrow Stromal Fibroblasts

Lawson,M.A., Barralet,J.E., Wang,L., Shelton,R.M. and Triffitt,J.T. (2004) Adhesion and Growth of Bone Marrow Stromal Cells on Modified Alginate Hydrogels. Tissue Engineering, 10, 1480-1491.

Murine Lung Homogenates

Lee,C.G., Link,H., Baluk,P., Homer,R.J., Chapoval,S., Bhandari,V., Kang,M.J., Cohn,L., Kim,Y.K. and McDonald,D.M. (2004) Vascular endothelial growth factor (VEGF) induces remodeling and enhances T H 2-mediated sensitization and inflammation in the lung. Nature Medicine, 10, 1095-1103.

Leporine Chondrocytes

Lee,J. and Son,Y. (2004) TGF-beta Stimulates Conversion of Fibrocartilage Phenotype of Costal Chondrocytes. Tissue Eng.Reg.Med, 1, 171-177.

Human Embryonic Kidney (HEK-293, 293-EBNA and 293-T) Cell Lines and Human Fibrosarcoma (HT-1080) Cell Line

Leitinger,B., Steplewski,A. and Fertala,A. (2004) The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2. J Mol Biol, 344, 993-1003.

Human Cardiac Left Ventricle Tissue

Liang,H., Müller,J., Weng,Y.G., Wallukat,G., Fu,P., Lin,HS, Bartel,S., Knosalla,C., Pregla,R. and Hetzer,R.(2004) Changes in myocardial collagen content before and after left ventricular assist device

application in dilated cardiomyopathy. Chinese Medical Journal, 117, 401-407.

Murine Lung Homogenate

Mcmillan,S.J. and Lloyd,C.M. (2004) Prolonged allergen challenge in mice leads to persistent airway remodelling. Clinical & Experimental Allergy, 34, 497-507.

Human Colonic Tissue

Mimura,T., Bateman,A.C., Lee,R.L., Johnson,P.A., McDonald,P.J., Talbot,I.C., Kamm,M.A., MacDonald,T.T. and Pender,S.L.F. (2004) Up-Regulation of Collagen and Tissue Inhibitors of Matrix Metalloproteinase in Colonic Diverticular Disease. Diseases of the Colon & Rectum, 47, 371-379.

Murine Dermal Tissue

Nomura,Y., Taniguchi,M., Miyata,M., Ariyasu,T., Yamauchi,H., Ikeda,M. and Kurimoto,M. (2004) Interferon-gamma liniment protects hairless mice against ultraviolet irradiation-induced skin damage. Biomedical Research, 25, 277-285.

Murine Lung Tissue

Ono, M., Sawa, Y., Mizuno, S., Fukushima, N., Ichikawa, H., Bessho, K., Nakamura, T., and Matsuda, H. (2004) Hepatocyte Growth Factor Suppresses Vascular Medial Hyperplasia and Matrix Accumulation in Advanced Pulmonary Hypertension of Rats. Circulation, 110, 2896-2902.

Murine Gingival Fibroblasts

Paik,J.W., Kim,C.S., Cho,K.S., Chai,J.K., Kim,C.K. and Choi,S.H. (2004) Inhibition of cyclosporin A-induced gingival overgrowth by azithromycin through phagocytosis: an in vivo and in vitro study. J Periodontol, 75, 380-387.

Murine Lung Tissue

Phillips,R.J., Burdick,M.D., Hong,K., Lutz,M.A., Murray,L.A., Xue,Y.Y., Belperio,J.A., Keane,M.P. and Strieter,R.M. (2004) Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. Journal of Clinical Investigation, 114, 438-446.

Leporine Bronchoalveolar Lavage Fluid

Schmidt,R., Ruppert,C., Markart,P., Lubke,N., Ermert,L., Weissmann,N., Breithecker,A., Ermert,M., Seeger,W. and Gunther,A. (2004) Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis. Toxicology and Applied Pharmacology, 195, 218-231.

Ovine, Leporine and Murine Tissue Constructs

Shieh,S.J. and Terada,S. (2004) Tissue engineering auricular reconstruction: in vitro and in vivo studies. Biomaterials, 25, 1545-1557.

Bovine Collagen

Skilbeck,C.A., Walker,P.G., David,T. and Nash,G.B. (2004) Disturbed flow promotes deposition of leucocytes from flowing whole blood in a model of a damaged vessel wall. British Journal of Haematology, 126, 418-427.

Human Fibrosarcoma (HT-1080) Cell Line Procollagen

Steplewski,A., Ito,H., Rucker,E., Brittingham,R.J., Alabyeva,T., Gandhi,M., Ko,F.K., Birk,D.E., Jimenez,S.A. and Fertala,A. (2004) Position of single amino acid substitutions in the collagen triple helix determines their effect on structure of collagen fibrils. J Struct Biol, 148, 326-337.

Murine Lung Homogenates

Sue,R.D., Belperio,J.A., Burdick,M.D., Murray,L.A., Xue,Y.Y., Dy,M.C., Kwon,J.J., Keane,M.P. and Strieter,R.M. (2004) CXCR2 Is Critical to Hyperoxia-Induced Lung Injury 1. The Journal of Immunology, 172, 3860-3868.

Human Lymphoblast-like Jurkat D1.1 and E6-1 Cell Lines and Human Primary Fibroblast Lines

Suppl,A., Yurovsky,V.V. and White,B. (2004) Effect of CD154-CD40 interactions on collagen production by fibroblasts. Arthritis Res. 3A, P062.

Human Dermal Fibroblasts

Suzuki,M., Tanabe,F., Nakamura,S., Motoda,R. and Orita,K. (2004) NK-355, an aminovinyl photosensitizing dye, enhances collagen production through TGF-β1 upregulation. Journal of Dermatological Science, 34, 56-58.

Murine Brain Tissue

Tang,J., Liu,J., Zhou,C., Alexander,J.S., Nanda,A., Granger,D.N. and Zhang,J.H. (2004) MMP-9 Deficiency Enhances Collagenase-Induced Intracerebral Hemorrhage and Brain Injury in Mutant Mice. Journal of Cerebral Blood Flow & Metabolism, 24, 1133-1145.

Murine Osteoblast Primary Culture

Valerio,P., Pereira,M.M., Goes,A.M. and Leite,M.F. (2004) The effect of ionic products from bioactive glass dissolution on osteoblast proliferation and collagen production. Biomaterials, 25, 2941-2948.

Murine Thrombi

Varma,M.R., Moaveni,D.M., Dewyer,N.A., Varga,A.J., Deatrick,K.B., Kunkel,S.L., Upchurch Jr,G.R., Wakefield,T.W. and Henke,P.K. (2004) Deep vein thrombosis resolution is not accelerated with increased neovascularization. J Vasc Surg, 40, 536-542.

Murine Primary Hepatic Stellate Cell Line

Wada,W., Kuwano,H., Hasegawa,Y. and Kojima,I. (2004) The Dependence of Transforming Growth Factor-β-Induced Collagen Production on Autocrine Factor Activin A in Hepatic Stellate Cells. Endocrinology, 145, 2753-2759.

Murine Pancreatic Stellate Cells

Watanabe,S., Nagashio,Y., Asaumi,H., Nomiyama,Y., Taguchi,M., Tashiro,M., Kihara,Y., Nakamura,H. and Otsuki,M. (2004) Pressure activates rat pancreatic stellate cells. American Journal of Physiology- Gastrointestinal and Liver Physiology, 287, 1175-1181.

Murine Dermal Biopsy

Yamamoto,T. and Nishioka,K. (2004) Animal model of sclerotic skin. VI: Evaluation of bleomycin-induced skin sclerosis in nude mice. Archives of Dermatological Research, 295, 453-456.

Murine Dermal Biopsy

Yamamoto,T. and Nishioka,K. (2004) Possible Role of Apoptosis in the Pathogenesis of Bleomycin-Induced Scleroderma. Journal of Investigative Dermatology, 122, 44-50.

Human Left Ventricle Tissue Biopsies

Zhang,J. and Narula,J. (2004) Molecular biology of myocardial recovery. Surg Clin North Am, 84, 223-242.

Human Pulmonary Fibroblasts

Zhang,L., Keane,M.P., Zhu,L.X., Sharma,S., Rozengurt,E., Strieter,R.M., Dubinett,S.M. and Huang,M. (2004) Interleukin-7 and Transforming Growth Factor-{beta} Play Counter-regulatory Roles in Protein Kinase C-{delta}-dependent Control of Fibroblast Collagen Synthesis in Pulmonary Fibrosis. Journal of Biological Chemistry, 279, 28315-28319.

2003

Murine Lung Homogenates

Blackburn,M.R., Lee,C.G., Young,H.W.J., Zhu,Z., Chunn,J.L., Kang,M.J., Banerjee,S.K. and Elias,J.A. (2003) Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. Journal of Clinical Investigation, 112, 332-344.

Trout Plasma, Endolymph and Otolith Explant

Borelli,G., Guibbolini,M.E., Mayer-Gostan,N., Priouzeau,F., De Pontual,H., Allemand,D., Puverel,S., Tambutte,E. and Payan,P. (2003) Daily variations of endolymph composition: relationship with the otolith calcification process in trout. Journal of Experimental Biology, 206, 2685-2692.

Human Fibroblasts

Cabral,W.A., Mertts,M.V., Makareeva,E., Colige,A., Tekin,M., Pandya,A., Leikin,S. and Marini,J.C. (2003) Type I Collagen Triplet Duplication Mutation in Lethal Osteogenesis Imperfecta Shifts Register of a Chains throughout the Helix and Disrupts Incorporation of Mutant Helices into Fibrils and Extracellular Matrix. Journal of Biological Chemistry, 278, 10006-10012.

Murine Lung Samples

Chung,MP., Monick,MM., Hamzeh,NY., Butler,NS., Powers,LS. and Hunninghake,GW. (2003) Role of repeated lung injury and genetic background in bleomycin-induced fibrosis. American Journal of Respiratory Cell and Molecular Biology 29, 375-380.

Murine Dermal Biopsy

Denton,C.P., Zheng,B., Evans,L.A., Shi-wen,X., Ong,V.H., Fisher,I., Lazaridis,K., Abraham,D.J., Black,C.M. and de Crombrugghe,B. (2003) Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice. Journal of Biological Chemistry, 278, 25109-25119.

Human Atherosclerotic Plaques

Goncalves, I., Moses, J., Dias, N., Pedro, L. M., Fernandes e Fernandes, Nilsson, J., and Ares, M. P. S. (2003) Changes Related to Age and Cerebrovascular Symptoms in the Extracellular Matrix of Human Carotid Plaques. Stroke 34, 616-622.

Murine Lung Homogenates

Huaux,F., Liu,T., McGarry,B., Ullenbruch,M., Xing,Z. and Phan,S.H. (2003) Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis 1. The Journal of Immunology, 171, 5470-5481.

Murine Fibroblasts

Huaux,F., Liu,T., McGarry,B., Ullenbruch,M. and Phan,S.H. (2003) Dual Roles of IL-4 in Lung Injury and Fibrosis 1. The Journal of Immunology, 170, 2083-2092.

Murine Lung Hydrolysates

Hutson,P.R., Crawford,M.E. and Sorkness,R.L. (2003) Liquid chromatographic determination of hydroxyproline in tissue samples. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 791, 427-430.

Leporine Chondrocytes

Ibusuki,S., Fujii,Y., Iwamoto,Y. and Matsuda,T. (2003) Tissue-Engineered Cartilage Using an Injectable and in Situ Gelable Thermoresponsive Gelatin: Fabrication and in Vitro Performance. Tissue Engineering, 9, 371-384.

Murine Osteoblast-like MC3T3-E1 Cell Line

Luppen,C.A., Smith,E., Spevak,L., Boskey,A.L. and Frenkel,B. (2003) Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. J Bone Miner Res, 18,1186-1197.

Murine Osteoblast-like MC3T3-E1 Subclone Cell Line

Luppen,C.A., Leclerc,N., Noh,T., Barski,A., Khokhar,A., Boskey,A.L., Smith,E. and Frenkel,B. (2003) Brief Bone Morphogenetic Protein 2 Treatment of Glucocorticoid-inhibited MC3T3-E1 Osteoblasts Rescues Commitment-associated Cell Cycle and Mineralization without Alteration of Runx2. Journal of Biological Chemistry, 278, 44995-45003.

Murine Pancreatic Stellate Cells

Ohnishi, N., Miyata, T., Ohnishi, H., Yasuda, H., Tamada, K., Ueda, N., Mashima, H., and Sugano, K. (2003) Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis. Gut 52, 1487-1493.

Porcine, Ovine and Tissue-Engineered Cardiac Valve Leaflets

Schenke-Layland,K., Opitz,F., Gross,M., Döring,C., Halbhuber,K.J., Schirrmeister,F., Wahlers,T. and Stock,U.A. (2003) Complete dynamic repopulation of decellularized heart valves by application of defined physical signals - an in vitro study. Cardiovascular Research, 60, 497-509.

Murine Lung Homogenate

Suzuki, H., Aoshiba, K., Yokohori, N., and Nagai, A. (2003) Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Augments a Murine Model of Pulmonary Fibrosis 1. Cancer Research 63, 5054-5059.

Murine Thrombi

Thanaporn,P., Myers,D.D., Wrobleski,S.K., Hawley,A.E., Farris,D.M., Wakefield,T.W. and Henke,P.K. (2003) P-selectin inhibition decreases post-thrombotic vein wall fibrosis in a rat model. Surgery, 134, 365-371.

Murine Osteoblast Primary Culture

Valério,P., Goes,A.M., Pereira,M.M. and Leite,M.F. (2003) Cytological and biochemical evaluation of osteoblast in contact with ionic products of bioactive ceramics. Key Engineering Materials, 240, 703-706.

Murine Plasma

Vergnes,L., Phan,J., Strauss,M., Tafuri,S. and Reue,K. (2003) Cholesterol and Cholate Components of an Atherogenic Diet Induce Distinct Stages of Hepatic Inflammatory Gene Expression. Journal of Biological Chemistry, 278, 42774-42784.

Murine Dermal Biopsy

Yamamoto,T. and Nishioka,K. (2003) Role of Monocyte Chemoattractant Protein-1 and its Receptor, CCR-2, in the Pathogenesis of Bleomycin-Induced Scleroderma. Journal of Investigative Dermatology, 121, 510-516.

Human Lung Fibroblast (8F1024, 8F1608 and 9F0892) Cell Lines

Yurovsky,VV. (2003) Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Enhances Collagen Production by Human Lung Fibroblasts. American Journal of Respiratory Cell and Molecular Biology, 28, 225-231.

2002

Murine Lung Homogenates

Blease, K., Schuh, J. M., Jakubzick, C., Lukacs, N. W., Kunkel, S. L., Joshi, B. H., Puri, R. K., Kaplan, M. H., and Hogaboam, C. M. (2002) Stat6-Deficient Mice Develop Airway Hyperresponsiveness and Peribronchial Fibrosis during Chronic Fungal Asthma. American Journal of Pathology 160(2), 481-490.

Human Pulmonary Fibrosis Fibroblasts, Normal Fibroblasts, U4A, U3A, and U4A/JAK1 Cell Lines and Murine Lung Samples

Huang,M., Sharma,S., Zhu,L.X., Keane,M.P., Luo,J., Zhang,L., Burdick,M.D., Lin,Y.Q., Dohadwala,M. and Gardner,B. (2002) IL-7 inhibits fibroblast TGF-β production and signaling in pulmonary fibrosis. Journal of Clinical Investigation, 109, 931-937.

Murine Lung Homogenates

Jain,V.V., Kitagaki,K., Businga,T., Hussain,I., George,C., O'Shaughnessy,P. and Kline,J.N. (2002) CpG-oligodeoxynucleotides inhibit airway remodeling in a murine model of chronic asthma. The Journal of Allergy and Clinical Immunology, 110, 867-872.

Murine Liver Samples

Kitamura,K., Nakamoto,Y., Akiyama,M., Fujii,C., Kondo,T., Kobayashi,K., Kaneko,S. and Mukaida,N. (2002) Pathogenic Roles of Tumor Necrosis Factor Receptor p55-Mediated Signals in Dimethylnitrosamine-Induced Murine Liver Fibrosis. Lab Invest, 82, 571-584.

Cultured Neonatal Heart Smooth-Muscle Cells

Langford,S.D., Trent,M.B. and Boor,P.J. (2002) Semicarbazide-sensitive amine oxidase and extracellular matrix deposition by smooth-muscle cells. Cardiovascular Toxicology, 2, 141-150.

Murine Lung Homogenates

Lanone,S., Zheng,T., Zhu,Z., Liu,W., Lee,C.G., Ma,B., Chen,Q., Homer,R.J., Wang,J. and Rabach,L.A. (2002) Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and-12 in IL-13-induced inflammation and remodeling. Journal of Clinical Investigation, 110, 463-474.

Murine Cardiac Samples

Li,Y.Y., Kadokami,T., Wang,P., McTiernan,C.F. and Feldman,A.M. (2002) MMP inhibition modulates TNF-a transgenic mouse phenotype early in the development of heart failure. American Journal of Physiology- Heart and Circulatory Physiology, 282, 983-989.

Murine Glomerular Mesangial Cells

Routh,R., McCarthy,K. and Welbourne,T. (2002) Troglitazone inhibits glutamine metabolism in rat mesangial cells. American Journal of Physiology- Endocrinology and Metabolism, 282, 231-238.

Murine Lung Tissue

Schuh,JM., Power,CA., Proudfoot,AE., Kunkel,SL, Lukacs,NW and Hogaboam,CM. (2002) Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to aspergillus in CCR4-/- mice. FASEB J. 16, 1313-1315.

Murine Lung Tissue

Suhara, H., Sawa, Y., Fukushima, N., Kagisaki, K., Yokoyama, C., Tanabe, T., Ohtake, S., and Matsuda, H. (2002) Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats. The Journal of Thoracic and Cardiovascular Surgery 123, 855-861.

Murine Dermal Tissue

Takeda,U., Utani,A., Wu,J., Adachi,E., Koseki,H., Taniguchi,M., Matsumoto,T., Ohashi,T., Sato,M. and Shinkai,H. (2002) Targeted Disruption of Dermatopontin Causes Abnormal Collagen Fibrillogenesis. Journal of Investigative Dermatology, 119, 678-683.

Murine Dermal Biopsy

Yamamoto,T. and Nishioka,K. (2002) Analysis of the effect of halofuginone on bleomycin-induced scleroderma. Rheumatology, 41, 594-596.

2001

Bovine Chondrocytes

Amiel,G.E., Yoo,J.J., Kim,B.S. and Atala,A. (2001) Tissue engineered stents created from chondrocytes. J Urol, 165, 2091-2095.

Human Granulosa Cells

Aston,K.E., Stamouli,A., Thomas,E.J., Vyas,S., Iredale,J.P., Arthur,M.J.P. and Richardson,M.C. (2001) Endocrinology and paracrinology Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases and their inhibitor in cultured human granulosa cells modelling corpus luteum function. Molecular Human Reproduction, 2, 26-30.

Murine Lung Homogenates

Blease,K., Jakubzick,C., Schuh,J.M., Joshi,B.H., Puri,R.K. and Hogaboam,C.M. (2001) IL-13 Fusion Cytotoxin Ameliorates Chronic Fungal-Induced Allergic Airway Disease in Mice 1. The Journal of Immunology, 167, 6583-6592.

Trout and Turbot Endolymph and Otoliths

Borelli,G., Mayer-Gostan,N., De Pontual,H., Boeuf,G. and Payan,P. (2001) Biochemical Relationships Between Endolymph and Otolith Matrix in the Trout (Oncorhynchus mykiss) and Turbot (Psetta maxima). Calcified Tissue International, 69, 356-364.

Human Dermal Fibroblasts

Bouma,P., Cabral,W.A., Cole,W.G. and Marini,J.C. (2001) COL5A1 Exon 14 Splice Acceptor Mutation Causes a Functional Null Allele, Haploinsufficiency of a1 (V) and Abnormal Heterotypic Interstitial Fibrils in Ehlers-Danlos Syndrome II. Journal of Biological Chemistry, 276, 13356-13364.

Leporine Lens Epithelial Cells

Ishida,I., Saika,S. and Ohnishi,Y. (2001) Effect of minoxidil on rabbit lens epithelial cell behavior in vitro and in situ. Graefe's Archive for Clinical and Experimental Ophthalmology, 239, 770-777.

Leporine Lens Epithelial Cells

Ishida,I.K.U. (2001) Experimental study on the efficacy of minoxidil in preventing postoperative capsular opacification. Journal of the Wakayama Medical Society, 52, 207-215.

Murine Lung Homogenates

Lee,C.G., Homer,R.J., Zhu,Z., Lanone,S., Wang,X., Koteliansky,V., Shipley,J.M., Gotwals,P., Noble,P. and Chen,Q. (2001) Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1. Journal of Experimental Medicine, 194, 809-822.

Human Left Ventricle Samples

Li, Y. Y., Feng, Y., McTiernan, C. F., Pei, W., Moravec, C. S., Wang, P., Rosenblum, W., Kormos, R. L., and Feldman, A. M. (2001) Downregulation of Matrix Metalloproteinases and Reduction in Collagen Damage in the Failing Human Heart After Support With Left Ventricular Assist Devices. Circulation 104, 1147-1152.

Murine Renal Tissue

Mizuno,S., Matsumoto,K. and Nakamura,T. (2001) Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney International, 59, 1304-1314.

Rat Fetal Lung Fibroblast (RFL-6) Cell Line

Samimi,A. and Last,J.A. (2001) Inhibition of Lysyl Hydroxylase by Malathion and Malaoxon. Toxicology and Applied Pharmacology, 172, 203-209.

2000

Rat Aortic Smooth Muscle Cells and Pig Auricular Chondrocytes

Brown, AN., Kim, BS., Alsberg,E. And Mooney,DJ.(2000) Combining Chondrocytes and Smooth Muscle Cells to Engineer Hybrid Soft Tissue Constructs. Tissue Engineering, 6, 297-305.

Human Primary Fibroblast Cultures

Kurasawa,K., Hirose,K., Sano,H., Endo,H., Shinkai,H., Nawata,Y., Takabayashi,K. and Iwamoto,I. (2000) Increased interleukin-17 production in patients with systemic sclerosis. Arthritis & Rheumatism, 43, 2455-2463.

Murine Cardiac Left Ventricles

Li,Y.Y., Feng,Y.Q., Kadokami,T., McTiernan,C.F., Draviam,R., Watkins,S.C. and Feldman,A.M. (2000) Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy. Proceedings of the National Academy of Sciences, 97, 12746.

Murine Renal Tissue

Mizuno,S. (2000) Reciprocal balance of hepatocyte growth factor and transforming growth factor-β 1 in renal fibrosis in mice. Kidney International, 57, 937.

Murine Lung Homogenate

Tokuda,A., Itakura,M., Onai,N., Kimura,H., Kuriyama,T. and Matsushima,K. (2000) Pivotal Role of CCR1-Positive Leukocytes in Bleomycin-Induced Lung Fibrosis in Mice 1. The Journal of Immunology, 164, 2745-2751.

1999

Bovine Articular Chondrocyte Cultures

Ioannidis,N., Kurz,B., Hansen,U. and Schünke,M. (1999) Influence of fulvic acid on the collagen secretion of bovine chondrocytes in vitro. Cell and Tissue Research, 297, 141-147.

Murine Dermis Samples

Jimenez,P.A. and Rampy,M.A. (1999) Keratinocyte Growth Factor-2 Accelerates Wound Healing in Incisional Wounds. Journal of Surgical Research, 81, 238-242.

Murine Tail Tendon

Kuznetsova,N. and Leikin,S. (1999) Does the Triple Helical Domain of Type I Collagen Encode Molecular Recognition and Fiber Assembly while Telopeptides Serve as Catalytic Domains? Effect of Proteolytic Cleavage On Fibrillogenesis And On Collagen-Collagen Interaction In Fibers. Journal of Biological Chemistry, 274, 36083-36088.

Murine Liver Tissue

Natsume, M. (1999) Attenuated liver fibrosis and depressed serum albumin levels in carbon tetrachloride-treated IL-6-deficient mice. Journal of Leukocyte Biology 66, 601-608.

Murine Bone Marrow Stromal Cells

Notoya,K., Nagai,H., Oda,T., Gotoh,M., Hoshino,T., Muranishi,H., Taketomi,S., Sohda,T. and Makino,H. (1999) Enhancement of Osteogenesis In Vitro and In Vivo by a Novel Osteoblast Differentiation Promoting Compound, TAK-778. Journal of Pharmacology and Experimental Therapeutics, 290, 1054-1064.

Murine Liver Tissue

Shimizu,I., Mizobuchi,Y., Yasuda,M., Shiba,M., Ma,Y.R., Horie,T., Liu,F. and Ito,S. (1999) Inhibitory effect of oestradiol on activation of rat hepatic stellate cells in vivo and in vitro. Gut, 44, 127-136.

Murine Liver Tissue and Primary cultures of Stellate cells and Hepatocytes

Shimizu,I., Ma,Y.R., Mizobuchi,Y., Liu,F., Miura,T., Nakai,Y., Yasuda,M., Shiba,M., Horie,T. and Amagaya,S. (1999) Effects of sho-saiko-to, a japanese herbal medicine, on hepatic fibrosis in rats. Hepatology, 29, 149-160.

Murine Liver Homogenate

Yasuda,M., Shimizu,I., Shiba,M. and Ito,S. (1999) Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis of the liver in rats. Hepatology, 29, 719-727.

1998

Human Osteoblasts

Andrade,A.L., Valqrio,P., Goes,A.M., Leite,M.F. and Domingues,R.Z. (1998) Behavior of Osteoblasts Cultured on Collagen Coated Bioactive Glass. Biomaterials, 19, 1019 – 1025.

Murine Tail Tendon

Knight,D.P., Nash,L., Hu,X.W., Haffegee,J. and Ho,M.W. (1998) In vitro formation by reverse dialysis of collagen gels containing highly oriented arrays of fibrils. Journal of Biomedical Materials Research, 41, 185-191.

Human Bone Marrow Fibroblastic Cells

Oreffo,R.O., Driessens,F.C., Planell,J.A. and Triffitt,J.T. (1998) Effects of novel calcium phosphate cements on human bone marrow fibroblastic cells. Tissue Eng, 4, 293-303.

Murine Aortic Explants

Tang,J., O'Callaghan,D., Rouy,S. and Godlewski,G. (1998) Quantitative changes in collagen levels following 830-nm diode laser welding. Lasers in Surgery and Medicine, 22, 207-211.

1997

Human Amniotic Membrane Samples

Hampson,V., Liu,D., Billett,E. and Kirk,S. (1997) Amniotic membrane collagen content and type distribution in women with preterm premature rupture of the membranes in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 104, 1087-1091.

Murine Cardiac Ventricles

Lubec,B., Hjelm,M., Hoeger,H., Gialamas,J. and Lubec,G. (1997) 4-Thiaproline reduces heart lipid peroxidation and collagen accumulation in the diabetic db/db mouse. Amino Acids, 12, 343-351.

Murine Articular Cartilage

Nakamura,M., Watanabe,J., Ogawa,R. and Kanamura,S. (1997) Immunohistochemical localization of type II and type I collagens in articular cartilage of the femoral head of dexamethasone-treated rats. The Histochemical Journal, 29, 645-654.

Addendum (Citations with Undetermined Experimental Model)

Asaumi,H., Watanabe,S., Taguchi,M., Nagashio,Y., Nomiyama,Y., Tashiro,M., Kihara,Y. and Otsuki,M. (2004) Inhibition of pancreatic stellate cell activation by green tea catechin through anti-oxidative effect. Pancreas, 29, 351.

Heemskerk,J.W., Siljander,P., Vuist,W.M., Breikers,G., Reutelingsperger,C.P., Barnes,M.J., Knight,C.G., Lassila,R. and Farndale,R.W. (1999) Function of glycoprotein VI and integrin alpha2beta1 in the procoagulant response of single, collagen-adherent platelets. Thromb Haemost, 81, 782-792.

Hsia-Wei Liu,P.D., Chen,C.H.W.A., Tsai,C.L.I.N., Lin,I.H. and Hsiue,G.H.O. (2007) Heterobifunctional poly(ethylene glycol)-tethered bone morphogenetic protein-2-stimulated bone marrow mesenchymal stromal cell differentiation and osteogenesis. Tissue Eng., 13, 1113-1124.

Gomperts,B.N. and Strieter,R.M. (2007) Fibrocytes in Lung Disease. Journal of Leukocyte Biology, 82, 449.

Ito,H., Steplewski,A., Alabyeva,T. and Fertala,A. (2006) Testing the utility of rationally engineered recombinant collagen-like proteins for applications in tissue engineering. J.Biomed.Mater.Res, 76, 551-560.

Li,Y.Y. and Feldman,A.M. (2001) Matrix metalloproteinases in the progression of heart failure: potential therapeutic implications. Drugs, 61, 1239-1252.

Tüyel,A.U., Valério,P., Öner,E.T. and Oktar,F.N. (2009) Biological activities of bioceramic powders of various natural biological origins. New Biotechnology, 25, S28.