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Single molecule manipulation: magnetic tweezers INESC-MN Magnets (NdFeB) Magnets (NdFeB) Resolution 5 nm [ ] Seidel et al, Nature Structural & Molecular Biology 11, 838-843 (2004) 52nd MMM Conference – Tampa FL November 2007 FA-05 3/38 EcoR124I
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Single molecule manipulation: magnetic tweezers

Feb 24, 2016

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Single molecule manipulation: magnetic tweezers. Magnets (NdFeB). Magnets (NdFeB). EcoR124I . Resolution 5 nm. [ ] Seidel et al, Nature Structural & Molecular Biology 11, 838-843 (2004). 3 /38. INESC-MN. FA-05. 52nd MMM Conference – Tampa FL November 2007. - PowerPoint PPT Presentation
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Page 1: Single molecule manipulation: magnetic tweezers

Single molecule manipulation: magnetic tweezers

INESC-MN

Magnets(NdFeB)

Magnets(NdFeB)

Resolution5 nm

[ ] Seidel et al, Nature Structural & Molecular Biology 11, 838-843 (2004)

52nd MMM Conference – Tampa FL November 2007 FA-05 3/38

EcoR124I

Page 2: Single molecule manipulation: magnetic tweezers

INESC-MN53rd MMM Conference – Austin TX November 2008

CG-05Micro Fabricated Structures (Without Fluidic Chamber)Spin Valves & Magnetic Tunnel Junctions

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Page 3: Single molecule manipulation: magnetic tweezers

Magnetic Tweezer, DNA manipulation, DNA translocation

IAC

IDC

V+, I+ V-, I-

10m

M.R.

ATP

FP6 BioMolSwitch

Page 4: Single molecule manipulation: magnetic tweezers

INESC-MN

Optical Scope – Vertical Switch

52nd MMM Conference – Tampa FL November 2007 FA-05 28/38

45 mA

IMT

0 mA

Page 5: Single molecule manipulation: magnetic tweezers

INESC-MN53rd MMM Conference – Austin TX November 2008

CG-05

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Micro Fabricated Structures (Without Fluidic Chamber)Spin Valves & Magnetic Tunnel Junctions

Page 6: Single molecule manipulation: magnetic tweezers

INESC-MN53rd MMM Conference – Austin TX November 2008

CG-05Bead DetectionIntermixing frequency

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