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SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

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Page 1: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your
Page 2: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

259a_13_CT

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Page 3: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

Advanced Sample & Assay Technologies

Better results — on any sequencing platform

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Page 4: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

Sample & Assay Technologies

Page 5: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

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Page 7: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

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Page 8: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

Join Keystone Symposia for Two Unique Events

HIV/AIDS:Strategies for an EndgameDecember 13, 2013 | 1:00–2:30 PMESTOur frst FREE, LIVEwebcast.

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Scientifc Organizers: Lincoln D. Stein,DoreenWare andMichael Schatz

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Discounted Abstract Deadline:November 19, 2013Student/Postdoc Scholarship ApplicationDeadline:November 19, 2013Abstract Deadline:December 18, 2013Discounted RegistrationDeadline: January 21, 2014

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CONFIRMED SPEAKERS(as of November 4, 2013):

Laura Clarke, EuropeanBioinformatics InstituteMarkGerstein, Yale UniversityDavid Haussler*, UC Santa CruzJill P. Mesirov, Broad InstituteJohnOverington, EuropeanMolecular Biology LaboratoryAjay Royyuru, IBMT.J.WatsonResearch CenterMichael Schatz, Cold SpringHarbor LaboratoryDan Stanzione, Universityof Texas at AustinLincoln D. Stein, OntarioInstitute for Cancer ResearchSusan Sunkin, Allen Institutefor Brain ScienceJason Swedlow, Universityof DundeeMattWood, AmazonWebServices, Inc.

*Keynote Speaker

www.keystonesymposia.org | 970.262.1230 | 800.253.0685

Page 9: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

PNASwww.pnas.org

Call for 2013

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The PNAS Editorial Board is nowaccepting nominations throughJanuary 10, 2014 for the 2013 CozzarelliPrize. This award recognizes scientificexcellence and will be given to six paperspublished in PNAS during 2013.

Nominations should be sent [email protected] and should include acitation and brief explanation of themerits of the work. The award recipientswill be recognized during the PNASEditorial Board Meeting and the NASAnnual Meeting Awards Ceremony onApril 27, 2014 in Washington, DC.

For more information and a list of previous winnersvisit www.pnas.org/cozzarelliprize.

ImagecourtesyofUniversity

ofCalifornia,B

erkeley.

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Page 10: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

Eppendorf®, the Eppendorf logo, Eppendorf PhysioCare Concept® and Eppendorf Reference® are registered Trademarks of Eppendorf AG, Germany.

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Page 12: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

Brought to you by the

Science/AAAS Custom

Publishing OfficeWebinar sponsored by

Exome Sequencing in Today’s Lab:Shifting the Paradigm in Translational and Clinical Research

REGISTER NOW!webinar.sciencemag.org

Next generation sequencing technologies have enabled a rapid expansion

toward the understanding of inherited disorders, cancer biology, drug devel-

opment, and treatment resistance. Exome sequencing has been increasingly

and successfully applied in the clinical research setting for identifying com-

mon single nucleotide variants, copy number variations, and small insertions

or deletions as well as rare de novo mutations that may explain Mendelian,

complex, and rare genetic disorders. Recent advancement in rapid and

low-cost exome sequencing make it an attractive alternative to traditional

targeted gene panel sequencing for clinical research, while maintaining the

possibility of discovering mutations in genes previously not associated with

a disorder. Furthermore, the exome encompasses approximately 1% of

the genome, yet contains approximately 85% of disease-causing muta-

tions, making exome sequencing easier and cheaper than whole genome

sequencing for identifying disease-causing variants in research.

Researchers are now applying proband-father-mother (trio) exome

sequencing to uncover variants that potentially either cause or modify the

condition under study. In this webinar, the audience will learn about the cur-

rent applications of exome sequencing in clinical research and its impact on

the future of health care.

During the webinar, the speakers will:

• Detail their clinical research exome workflow from DNA to data analysis

• Compare exome sequencing to other variant screening approaches

• Shed light on the current paradigm shift to exome sequencing for clinical

research

• Discuss how this shift may impact future clinical applications of exome

sequencing

• Answer your questions live on air!

Wednesday, December 4, 201312 noon Eastern, 9 a.m. Pacific, 5 p.m. UK, 6 p.m. Central Europe

Christian Marshall, Ph.D.

The Hospital for Sick Children

Toronto, Canada

Christian Gilissen, Ph.D.

Radboud University Medical Centre

Nijmegen, The Netherlands

Speakers

Page 13: SimpleStep life easier · 2013-12-16 · kits – make your life easier. Advanced Sample & Assay Technologies Better results — on any sequencing platform Get the most from your

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