www.le.ac.uk Why do we need an EM research into ageing network? Simon Conroy Geriatrician & Honorary Senior Lecturer
Jul 16, 2015
www.le.ac.uk
Why do we need an EM research into ageing network?
Simon ConroyGeriatrician & Honorary Senior Lecturer
Outline
• Why ageing research at all?
• Existing support for research & delivery
• UK Clinical Research Network
• Ageing speciality group
• Possible roles for EMRAN
Why do we need research into older people?
• To improve patient care
• To test interventions
– Valid findings
– Intervention effect & health economics
– Generalisability
• Old & frail vs. old & fit
Why do we need research into older people?
• Historically older people have been excluded from clinical trials (PREDICT study)
– Ageism – societal & clinicians/researchers
– Practical features to support participation
– Study design – excluding people who can’t give consent
Leading to treatments that are not tested in the populations for whom they are given (OR not given)
Older people & research participation
• http://www.crn.nihr.ac.uk/ageing/pcpie/
Frailty related evidence base
Existing support - EM
• Support for portfolio development
– http://www.rds-eastmidlands.nihr.ac.uk/
• Funding for portfolio development
– http://www.clahrc-em.nihr.ac.uk/clahrc-em-nihr/index.aspx
• Research delivery
– http://www.enrich.dendron.nihr.ac.uk/news-item.php?ID=141
– http://www.crn.nihr.ac.uk/ageing/
Existing support - EM
• Translating research into practice
– http://emahsn.org.uk/
• Patient & public involvement
– http://emahsn.org.uk/public-involvement/
– Local groups
UK Clinical Research Network
• Recruited over 600k study participants in 2013/14
• Infrastructure
– Set up clinical studies
– Support delivery
– Research training
– Patient & public involvement
NIHR CRN: East Midlands
• Population: 4.5 M
• Derbyshire, Lincolnshire, Nottinghamshire, Leicestershire & Rutland, Northamptonshire
• 10 NIHR hosted research networks
• 15 NHS Trusts
• 19 CCGs
• 8 universities
• Budget £23 M
0 2000 4000 6000 8000 10000 12000
Ageing
Dermatology
Health services and delivery research
Musculoskeletal disorders
Oral and Dental Health
Primary Care
Public Health
Recruitment by County & Specialty in 21014-15
Derby City & County Lincolnshire
LLR Leicester City & County & Rutland Northamptonshire
Notts City & County Non-NHS - East Midlands LCRN
Ageing speciality group - remit
• Healthy ageing and frailty
• Organising and delivering interventions for health promotion
• Ageing process and early markers of ill health
• Modelling links between disease and functioning
• Education and lifelong learning
• Environmental conditions for ageing well
• Effectiveness of clinical and social care
Acronym Active Status Trust Name Local Investigator Lead Specialty
CLOTS-3
Closed - in follow-
up
Chesterfield Royal Hospital NHS Foundation
Trust Dennis, Prof M Stroke
CLOTS-3
Closed - in follow-
up
Sherwood Forest Hospitals NHS Foundation
Trust Cooke, Dr Justin Stroke
CLOTS-3
Closed - in follow-
up United Lincolnshire Hospitals NHS Trust
Leach, Dr Simon; Mangion, Dr
David Stroke
PD REHAB
Closed - in follow-
up University Hospitals of Leicester NHS Trust
Dementias and
neurodegeneration
Survey of Older Adults' views on Advance Care Planning in UK &
Japan
Closed - in follow-
up University Hospitals of Leicester NHS Trust Musa, Irfan Primary Care
Survey of Older Adults' views on Advance Care Planning in UK &
Japan
Closed - in follow-
up Formerly Nottingham City PCT Musa, Dr Irfana Primary Care
Survey of Older Adults' views on Advance Care Planning in UK &
Japan
Closed - in follow-
up Formerly Nottinghamshire County Teaching PCT Musa, Dr Irfana Primary Care
Hypertension in Dementia - Feasibility Study In Set-Up Nottingham University Hospitals NHS Trust Van Der Wardt, Dr Veronika Primary Care
The FINOF Study Open Nottingham University Hospitals NHS Trust Sahota, Prof Opinder Musculoskeletal disorders
IVANOF1 Study Open Nottingham University Hospitals NHS Trust Moppett, Dr Iain K Injuries and emergencies
The effect (s) of routine administration of Fluoxetine in patients
with a recent stroke - FOCUS Open United Lincolnshire Hospitals NHS Trust
Mangion, Dr David; Leach, Dr
Simon Stroke
PRoBaND: Parkinson's Repository of Biosamples and Network
Datasets Open University Hospitals of Leicester NHS Trust Critchley, Peter
Dementias and
neurodegeneration
PRoBaND: Parkinson's Repository of Biosamples and Network
Datasets Open Derby Hospitals NHS Foundation Trust Bajaj, Dr Nin
Dementias and
neurodegeneration
PRoBaND: Parkinson's Repository of Biosamples and Network
Datasets Open United Lincolnshire Hospitals NHS Trust Sharma, Prof Jagdish
Dementias and
neurodegeneration
Clinical Trial for Elderly Patients with Multiple Diseases (CHROMED) Open Formerly Lincolnshire Teaching PCT
Siriwardena, Prof Aloysius
Niroshan Respiratory disorders
Clinical Trial for Elderly Patients with Multiple Diseases (CHROMED) Open NHS Lincolnshire East CCG
Siriwardena, Prof Aloysius
Niroshan Respiratory disorders
Clinical Trial for Elderly Patients with Multiple Diseases (CHROMED) Open NHS Lincolnshire West CCG
Siriwardena, Prof Aloysius
Niroshan Respiratory disorders
Clinical Trial for Elderly Patients with Multiple Diseases (CHROMED) Open NHS South Lincolnshire CCG
Siriwardena, Prof Aloysius
Niroshan Respiratory disorders
Increasing physical activity in older adults Open Lincolnshire Partnership NHS Foundation Trust Collins, Dr Iheanyichukwu Esiwe Primary Care
Hypertension in Dementia - Feasibility Study Open Leicester City PCT Primary Care
Hypertension in Dementia - Feasibility Study Open Formerly Derby City PCT Van Der Wardt, Dr Veronika Primary Care
Hypertension in Dementia - Feasibility Study Open Formerly Derbyshire County PCT Van Der Wardt, Dr Veronika Primary Care
Hypertension in Dementia - Feasibility Study Open Formerly Lincolnshire Teaching PCT Van Der Wardt, Dr Veronika Primary Care
Hypertension in Dementia - Feasibility Study Open Formerly Nottinghamshire County Teaching PCT Van Der Wardt, Dr V Primary Care
Hypertension in Dementia - Feasibility Study Open NHS Mansfield and Ashfield CCG Van Der Wardt, Dr V Primary Care
Hypertension in Dementia - Feasibility Study Open NHS Nottingham City CCG Van Der Wardt, Dr V Primary Care
OPTIMAL: Better health for care homes Open NHS Nottingham City CCG Pitchford, Russell
Dementias and
neurodegeneration
OPTIMAL: Better health for care homes Open Nottinghamshire Healthcare NHS Trust Pithford, Richard
Dementias and
neurodegeneration
Psychobehavioural Factors Associated with Optimal Vaccine
Possible roles for EMRAN
• Navigation & translation
• Connection & coordination
• Peer-support
• ‘Memory’